LOCUS       c00040_gnlPro..        14079 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LJKGGHGH_40.
ACCESSION   c00040_gnlPro..
VERSION     c00040_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:23:19
            Original ID  :: gnl|Prokka|LJKGGHGH_40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14079
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1074
                     /locus_tag="ctg40_1"
                     /transl_table=11
                     /translation="VPQEEKPAAAPAPEAQVNLSPEEQAMVDQFAQKIDITNSQQVLQY
                     GSACQKKIGDFSEAALSKVSTKDLGEVGDMITNLIGELKSFDANEEQQKGIMGFFKKKT
                     SQLDALKTKYDKTETNVEKIQSMLEAHQVQLLKDIAMLDKMYELNMAYFKELSMYILAG
                     KKKLADVRANELQQAMDKAKVSGLPEDAQAARDLADQCERFEKKLYDLELTRNISLQMG
                     PQIRLLQNNNTMMAEKIQSTIVNTIPLWKNQMVLALGLAHSQQAMQAERAVTNMTNDLL
                     KKNAEALKLGTIETAKESQRGIVDIETLQQTNKSLIETLDELNKIQSEGRAKRAAAEQE
                     LTRIEDELKTKMMEIRS"
     protocluster    1..14079
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2887:11671]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2888..11671
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14079
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14079
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             1076..1834
                     /locus_tag="ctg40_2"
                     /transl_table=11
                     /translation="MANADFSQNKQTAPGGFDAGSYREKAKPEQAVTLTPRQQKLAALE
                     AKLPAALSTRAAALALSVVVMLAAFFGFGSAKLRGKYNTARQWFTAGVAADNGYNLSEE
                     LTTRENTAANILTTASNTLGADSAEVLAAQTALNDFSACLQAVQNGGKSQSLTSLPYYQ
                     GSAMHALYQADQALGAAIDQLYAKLQEQAADPMKMGAVQGQYGQFNSAATIIGTLQYNT
                     AVYEYQKEVGGFPASVLGALSGVKEVEPFA"
     CDS             1831..2745
                     /locus_tag="ctg40_3"
                     /transl_table=11
                     /translation="MKNFAKRISALVLAVVLSAAVLCPAAFAAQLPSLPKDQCVVDGAG
                     VLSSSTVQTITELNAQLESSCSGAQIGVLTVEYTGNDSTEDYATQAFNAWGIGSSSNNN
                     GVLILLVMESAQYADGDYYLTYGDGFRNTTLAKQSSAIAQTMEDQFAAKNYDGAVTTCA
                     RNVANTIADIYGVSLSGGTGNTVQPGYQGSQSRGGSTLTDILTLVVSVVLLIVIIRSMA
                     YVFASPCGWLWCFGGPRPPRGRRRGPHNPPPPGGFYGGFGGMGGGSFGGGAGRGGFGGG
                     SFGGGFGGMGSGSSHGGGGGRGR"
     CDS             2888..4093
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_4"
                     /sec_met_domain="PALP (E-value: 5.1e-93, bitscore: 301.5,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLDKIYHAAFVLKDVARKTDLIEAPKLSKDCQLYLKTENLQAT
                     GSFKVRGAYYKISQLSEEESAKGVIACSAGNHAQGVALAATRRSIRSIVCMPDGAPLMK
                     VENTKNLGAEVCLVPGTYDEAHDKAVQLQKEYDMTFIHPYDDEQVIAGQGTIGLEILDQ
                     LPDVDAVVVPVGGGGLISGIAFAIKTLRPEVKVYGVQAEGAPSMYRSLHEHKYQTLKSA
                     STFADGIQVKTPGELTYQLCEQYVDDIVTVTEDETAAAILSLMENQKLVAEGAGAVPVA
                     AVLFHKLPVEGKKVACVISGGNIDVNILNRVITRGLVMSGRKANLTIALEDKPGQLKKV
                     AEVVSRCGSNVVSVQHDGSDPNMPISSCFLKLTLETRDAAQIEQIRTELTKAGFQLVTE
                     RV"
     CDS             4280..4654
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ribonuc_L-PSP"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1038:Endoribonuclease L-PSP (Score: 150.2; E-value:
                     8.5e-47)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg40_5"
                     /sec_met_domain="Ribonuc_L-PSP (E-value: 1.9e-47, bitscore:
                     150.2, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVSTANAPAAIGPYSQALDLGNMVFVSGQIPVDPATGTMADTV
                     EQQAAQSLANLKAILAEAGLSMNNVVKTVIFLADINDFAAVNAEYAKAFAEPFPARSCV
                     QVAAIPKGAKLEIECIAVRD"
     CDS             complement(4743..5960)
                     /locus_tag="ctg40_6"
                     /transl_table=11
                     /translation="MKLREWNAHLHGLVVFRALLNDPVVAKLLDLTDRMEAGCSSYGPV
                     CDAVAAFEAALFEYTTNWGSYLSNAVLEAETICVRQAAAGQLDALLQSALDSELQFLQQ
                     LCGLTLDELFQTAYSEQAQRPELAFLPRWQTCELDLAAAYAQRMSEVGKKGYGMFAKHH
                     VFTVENGQLVPVKYPDPQRLSELPGYEKEREKVIANTKALLAGMPANNVLLYGDAGTGK
                     SSAVKAIANEFAPEGLRLVEVKKNQLYQIPDLMDKLAANPLKFILFIDDLSFTANDDNF
                     AALKAILEGSVGGRAQNIAVYATSNRRHLIKETLSDRTGDDIHEADTRQELMSLSARFG
                     LTVTFQRPEKARFETILEELAKQHNIQMPTEQLLLKAEAFALRAGGRSPRVAKQFIEQC
                     EAGVQK"
     CDS             6486..8150
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-51, bitscore:
                     163.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLNGSQIFVEVLCEQGVDTLFGYPGGAVLNLYDELYKNADRITH
                     VLTAHEQGAAHAADGYARATGRTGVVLATSGPGATNLVTGIATAYMDSVPMVAFTGNVP
                     TSSIGKDGFQEAYIEGITVPITKHNFTVRRVEDLADTMRAAFRIAQSGRKGPVLVDIPK
                     DVTAAVCEFTPKQPEPIRTVTTYNEEQVHWAADLINAAQRPLVYFGGGVRSAASCQPLR
                     DLLHKAEIPATYTLMAAGVVPYGDPMNLGMLGMHGCYTSNRAVAECDVLIAVGTRFSDR
                     VALNPKTFAKNATIIQIDIDASELGKNVDVDLSIVGDAAYVLNAMLPQIKPAKHPDWMT
                     MIQSWQAQDYHPVSDPTRLMPHQVIGEVCNQCGPDAVYVTDVGQHQMWAAQYLRHTKSR
                     GFITSGGLGTMGFGYGAAIGAQMALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIIT
                     VIFNNSVLGMVRQWQTSFYGKRYSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFA
                     DALQQKGPTWIECIIDKDEKVLPMIPGGGDINDIIME"
     CDS             8166..8729
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_8"
                     /sec_met_domain="ALS_ss_C (E-value: 1.8e-28, bitscore:
                     88.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDSEKALERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHIQKPPQEVRSVQLPPPGARRA"
     CDS             8828..9847
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_9"
                     /sec_met_domain="IlvN (E-value: 7.1e-75, bitscore: 240.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1e-65, bitscore: 210.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHDNFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVSELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGFSKMRYSISNTAEYGDYRTGKRLITEETRKEM
                     KKVLTEIQDGTFASEFLTEMSPKGGRKVHFLAKRRMEAELPIEKVGAELRSMMSWLKK"
     CDS             10013..11671
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_10"
                     /sec_met_domain="ILVD_EDD (E-value: 3.2e-224, bitscore:
                     735.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDNVTKGSERAPNRSLFYALGYTPEELERPLIGVVSAYSEIVP
                     GHMNLDKIAEAVKAGVQMAGGTPILIPAIGVCDGIAMGHVGMKYSLASRELICDSVETM
                     LMAHQLDGLVLVPNCDKIVPGMVMAAVRMDVPAVVCSGGPMLAGTYGGEEVSLSKMFEA
                     VGAYKAGMITDEQLEDCTCNCCPSCGSCSGMYTANSMNCLCEAIGIALPGNGTIPAVYS
                     KRLQLAKHAGMAVMEMVRKGITARQIINERSIRNALTCDMALGCSTNTVLHLLAIAYEA
                     GVPIDLKLFNEISAKTPNLCHLAPAGPTHMPDLYAAGGIPAVQAELAKKGLLDLDVPTV
                     TGKTLGENIKGAHILNEKAIRPIENPYSETGGLQILWGNIAPDGCVVKRSAVAPEMQQH
                     SGPARVFNSEEEAIAAIYAGKIVPGDVVVIRYEGPKGGPGMREMLNPTSALAGMKLDKT
                     VALITDGRFSGASRGAAIGHVSPEAASGGPIGLIEEGDTISIDIPNASITLEVSDAVLA
                     ERKAKYVAPEPNIKTGWLSRYARMVTSANLGAVLK"
     CDS             complement(11718..12389)
                     /locus_tag="ctg40_11"
                     /transl_table=11
                     /translation="MESTISAAPQISIDREKTLRSHRRYWVLRRAQDIVFSLLALILLA
                     PLALLISLAIVLDSPGDGAIFRQRRVGRDGKLFWLYKFRTMCPDAEEQLNELLSQNQMD
                     GPVFKIKGDPRITRVGRFLRKTSLDELPQLLNVLQGDMSIVGPRPALPREVELYSDYQR
                     QRLYVTPGLSCYWQIAPHRNEMSFDEWVALDMKYIQERSFWVDWKIIFLTVRAMLMKYG
                     E"
     CDS             12832..13083
                     /locus_tag="ctg40_12"
                     /transl_table=11
                     /translation="MKYDERACKFNIDTGCVELLLRDGRKISINCTGVEDALDVTMAQQ
                     TELDYLIYNDPLGYADLILNGDPEEYLKNAAGSHGLED"
     CDS             complement(13182..13358)
                     /locus_tag="ctg40_13"
                     /transl_table=11
                     /translation="LNKKKKSNKSGYPDEAIKTLARCFYPSMVEFFNSEEGQREYEEWL
                     KEQEALQALPVAA"
     CDS             complement(13376..14077)
                     /locus_tag="ctg40_14"
                     /transl_table=11
                     /translation="RSKKWASKPLLDDAGKPVLQKNGKPVLKKSYSVLQDDFFHYMHNA
                     GYTDVERGERGSTEEHLTVTQFKVQREQERLDSLTAQIDQKEQHLTQTNKTLSKTEKEL
                     AAVQKKATLTKEALIHVRDLDYIGKRTFLGNYSLTEEEFSKLKKQADHGYMMDVENRRL
                     KEELSTAKKEAVRWSNKYHDLWYDVKPYLDALHRAPELVRGFLEKILAPKQERTMNVPQ
                     RSRKRGQDMEL"
ORIGIN
        1 gtgccgcagg aggaaaagcc cgccgctgcc cctgccccgg aggcacaggt gaacctgagc
       61 cccgaggagc aggccatggt ggatcagttt gcccagaaga tcgatatcac caacagccag
      121 caggtgctgc agtacggctc tgcctgccag aagaagatcg gcgatttctc cgaagcagcc
      181 ctctccaagg tgtccaccaa ggatctgggc gaggtgggcg atatgatcac caacctcatt
      241 ggcgagctga agagctttga tgccaacgag gagcagcaga agggcattat gggcttcttc
      301 aagaagaaaa ccagccagct ggatgccctc aagaccaagt acgacaagac cgagaccaac
      361 gtggaaaaga tccagtccat gctggaagcc catcaggtgc agctgctcaa ggatatcgct
      421 atgctggaca agatgtacga gctgaacatg gcctacttca aggaactgag catgtatatc
      481 cttgccggca agaaaaagct ggctgatgtg cgtgccaacg aattgcagca ggctatggac
      541 aaggccaagg tctccggtct gccggaggat gcacaggccg cccgcgacct tgccgaccag
      601 tgcgagcgct ttgagaaaaa gctgtatgat ctggagctga cccgcaacat cagtttgcag
      661 atgggcccac agatccgtct gctgcagaac aacaacacca tgatggcgga aaagatccag
      721 tccaccatcg tgaacaccat cccgctgtgg aagaaccaga tggtgctggc actggggctg
      781 gcacacagcc agcaggccat gcaggccgag cgcgccgtga ccaacatgac caacgacctg
      841 ctgaagaaga acgccgaggc gctgaagctg ggcaccattg agactgccaa ggagagccag
      901 cgcggcatcg tggatatcga gacgctacag cagaccaaca agagcctgat cgagacgctg
      961 gacgaactga acaagatcca gagcgagggc cgcgcaaagc gcgccgccgc cgagcaggag
     1021 ctgacccgca tcgaggacga actgaaaacc aaaatgatgg agatccggag ctgaaatggc
     1081 aaacgctgat ttttctcaga acaaacaaac cgctcccggc ggctttgacg cgggcagcta
     1141 ccgcgaaaaa gcaaagccgg agcaggccgt aacgctgacc ccgcgccagc agaagctggc
     1201 cgcactggaa gcaaagctgc ccgctgcgct ttccacccgg gcggcggcgc tggccttgag
     1261 cgtagtggtg atgctggccg cctttttcgg ctttggcagc gccaagctgc gcggcaagta
     1321 caacactgcc cgtcagtggt tcaccgcagg ggtcgccgcc gacaacggtt ataacctgag
     1381 cgaggagctg accacccggg agaatacggc ggcgaatatt ctgaccactg cctccaacac
     1441 ccttggcgca gacagcgccg aggtgctggc tgcacagacg gcgctgaacg atttctccgc
     1501 ttgtctgcag gcggtgcaga acggcggtaa aagccagtcg ctgacctcgc tgccctatta
     1561 tcagggcagc gcgatgcacg cgctgtatca ggccgatcag gcactgggcg ctgccatcga
     1621 ccagctgtat gcaaagttgc aggagcaggc cgccgacccc atgaagatgg gcgcggtgca
     1681 ggggcagtac ggtcagttca acagcgcagc caccatcatt ggtactttgc agtacaatac
     1741 ggcggtgtat gaatatcaga aggaagtcgg cggcttcccg gccagtgtgc tgggcgcttt
     1801 gtccggcgtg aaggaggttg aacccttcgc atgaaaaact ttgcaaaacg tatcagcgca
     1861 ctggtgctgg ccgtggtgct cagcgcggcg gtgctgtgcc cggcggcctt tgccgcccag
     1921 ctgcccagcc tgcccaaaga tcagtgcgtg gtggatggtg ctggtgtgct gagcagcagc
     1981 accgtgcaga ccatcaccga actgaacgcc cagttggaat ccagctgcag cggcgcgcag
     2041 atcggtgtac tgacagtaga atacacaggc aatgattcca cagaggatta cgccacacag
     2101 gctttcaacg cctggggtat cggttcgtcc tccaacaata acggtgttct gatcctgctt
     2161 gtgatggagt cggcacagta tgcggacggc gactactacc tgacctatgg cgacggcttc
     2221 cgcaacacca cgctggcaaa gcagtccagc gccatcgccc agaccatgga agaccagttc
     2281 gccgcaaaga attatgacgg cgcggtgacc acctgtgccc gcaacgtggc aaacaccatc
     2341 gcggatattt acggggtcag cctttccggc ggcaccggca acaccgtgca gcccggctat
     2401 cagggcagcc agagccgcgg cggcagcacc ctgaccgaca tcctgaccct tgtggtcagc
     2461 gttgtgttgc tcatcgtcat catccggtcg atggcctatg tttttgccag tccctgcggc
     2521 tggctgtggt gcttcggtgg gccgcggcct ccccgtggac ggcggcgcgg cccgcataac
     2581 ccgcccccgc cgggcggctt ctacggcggc tttggcggca tgggcggcgg ctccttcggg
     2641 ggcggtgccg ggcgcggcgg tttcggcggc ggcagctttg gcggcggctt cggtggcatg
     2701 ggcagcggtt ccagccatgg cggcggtggt ggccgtgggc ggtaatgaga ataaaaagag
     2761 aaaggcggtg gctttaccac tgcctttctc ttttttacgc cttttatcgt gaatggaatt
     2821 catttgacaa aacaattttt gtaacttata ctggatgaca tcacgaaaaa taaaggaagt
     2881 atctgtcatg ctgactctgg ataagatcta ccacgccgcc tttgtactga aggacgtagc
     2941 gcgcaagacc gacctcatcg aagcccccaa gctgtccaag gactgccagc tgtaccttaa
     3001 gaccgagaac ctgcaggcca ccggcagctt taaggtgcga ggcgcttact ataaaatcag
     3061 ccagctttct gaggaggaga gcgccaaggg cgtcattgcc tgctctgcgg gcaaccatgc
     3121 gcagggggtg gcgctggcgg ctacccggcg cagcatccgc agcatcgtct gtatgccgga
     3181 cggcgcaccc ctgatgaagg tggaaaacac caaaaatctg ggcgcggagg tctgtcttgt
     3241 gcccggcacc tacgacgaag cccacgacaa ggccgtgcag ctgcaaaagg agtacgacat
     3301 gacctttatc cacccctacg atgacgagca ggtcatcgcc gggcagggta ccatcggctt
     3361 ggagatcctt gaccagctgc cggatgtgga cgctgtggtg gtgccggtgg gcggcggcgg
     3421 actgatttcc ggtattgcct ttgccatcaa gaccctgcgc ccggaggtca aggtgtacgg
     3481 cgtacaggcc gagggtgccc ccagtatgta ccgcagcctg cacgagcaca agtaccagac
     3541 cctgaaatct gcttccacct ttgcggacgg tattcaggtc aagaccccgg gcgagctgac
     3601 ctatcagcta tgcgagcagt atgtggacga tatcgttacc gtgaccgagg acgagacggc
     3661 ggcggccatt ctctccctga tggagaacca gaagctggtg gctgagggtg caggcgctgt
     3721 gccggtggca gcagtactgt tccacaagct gccggtggag ggcaaaaagg tggcctgcgt
     3781 catctccggc ggcaacattg atgtgaacat cctgaaccgc gtcatcaccc gcggtcttgt
     3841 gatgagcggc cgcaaggcaa acctgaccat cgcgctggag gacaagcccg gccagctgaa
     3901 aaaggtggcc gaggtggtat cccgctgcgg cagcaatgtg gtgtcggtgc agcatgacgg
     3961 ctccgacccc aatatgccca tctccagctg cttcctcaag ctgacgctgg agacccgcga
     4021 tgccgcccag atcgagcaga tccgcaccga gctgaccaag gccggtttcc agctggtcac
     4081 cgagcgggtg taaacttcat cgtttgcaag agtgaaagcc ttcccccgga cggggaaggt
     4141 ggatgcgaac gtagtgagca gacggatgag ggcgcaggca agcagcagct tacgggaaat
     4201 taccccctcg tctggctcta tccgaagaaa aaagcgaatt tgttctaaac ttgatgtaat
     4261 ataaaggaga aaatatacta tgaaagtcgt atctaccgcc aacgcacctg ccgccatcgg
     4321 cccttacagt caggcactgg atctgggcaa catggtgttt gtttccgggc agatcccggt
     4381 agaccccgcc accggcacca tggccgatac cgtggagcag caggccgccc agagccttgc
     4441 taacctgaag gcgattctgg ccgaggcggg gctttccatg aacaacgtgg tcaagacggt
     4501 gatctttctg gccgatatca acgattttgc cgcagtgaac gcagagtacg ccaaggcctt
     4561 tgccgagccg ttccccgccc gcagctgcgt gcaggtggca gccatcccca agggcgcaaa
     4621 gctggagatc gagtgcatcg ccgtgcggga ctgagcgaaa aataagacaa gaaaagcggg
     4681 acaccggagc atctgcggat gctttggtgt cccgtttttg ataacgttta aaactggtgc
     4741 atttacttct gcacaccggc ctcgcattgc tcgatgaact gcttggccac ccgggggctg
     4801 cggccgccgg cacgcagggc aaaggcctcg gccttgagca gcagctgctc ggtgggcatc
     4861 tggatgttgt gctgctttgc cagctcctcc agaatggtct cgaaccgtgc cttctccggc
     4921 cgctggaagg tgaccgtaag gccgaaccgg gcggaaaggc tcatcaactc ctgccgggtg
     4981 tcggcttcat ggatgtcgtc gccggtgcgg tccgagaggg tttccttgat gaggtggcgg
     5041 cggttggagg tggcgtacac cgcaatgttc tgagcgcgtc cgcctacgct gccctccaag
     5101 atggccttca aggcggcaaa gttgtcgtcg ttggcggtaa agctcagatc gtcgatgaac
     5161 aaaatgaact tgagcgggtt tgccgccagc ttgtccatca ggtcggggat ctgatacagc
     5221 tggttctttt ttacctctac cagccgcagt ccctcgggcg caaactcgtt ggcaatggcc
     5281 tttaccgcgc tggatttgcc ggtaccggcg tcaccgtaca gcagcacatt gttggcgggc
     5341 atcccggcta gcagtgcctt tgtgttggcg atcacctttt cccgctcctt ctcgtagccg
     5401 ggcagctcgg aaaggcgctg cgggtcgggg tattttaccg gcacaagctg gccgttctcc
     5461 accgtgaata catggtgctt tgcaaacata ccgtagccct ttttgcccac ctcgctcatg
     5521 cgctgggcgt aggcggcggc aaggtcgagc tcacaggtct gccaccgggg caggaaagcc
     5581 agttccggcc gctgcgcctg ctccgagtag gcggtctgga acagctcgtc cagcgtcagc
     5641 ccgcacagct gctgcaaaaa ctgcagctcg ctgtccaagg cgctttgcag cagcgcgtcc
     5701 agctgcccgg cagcggcctg ccgcacgcag atggtctcgg cctccagcac agcattgctc
     5761 aggtagctgc cccagttggt ggtgtactcg aacaaagcgg cctcaaaggc ggctacggca
     5821 tcgcataccg ggccgtagga ggagcagccc gcctccatgc ggtcggtcag gtctaaaagc
     5881 tttgccacaa cagggtcgtt cagcagggcg cggaacacaa caagcccatg cagatgggca
     5941 ttccattctc ttaatttcat aggtcgatcc cttttcctct ccaatagcac ataccctaca
     6001 aaacgcaggt acgcggatat caaaagtata cagcggttcg ggcggggatg caaggggtgt
     6061 taaaaatgct tcatctttgg gctgattcag gttacaaatt gtcgattgac aaaagcccgg
     6121 tttatagtat aatttacatc aacaaatgcg cagatgggaa aaagtaccac acgatcccca
     6181 ctgttcagag agctgccgtc tggtgcaagg cagtcagcgt ttcgtgcgga aaatcatccc
     6241 ggagcagcct gcccaacggg tgcaaacccc tgtaagcagc gccggttgca gccgttaccg
     6301 tgcagggctt tgttggaagc ccgtgagagg gtgtgcacag cacgccaacg agagtggtac
     6361 cgcagagagc ttgatgttac aaggtctttg tctcttgaag aaagcagggg acaagggctt
     6421 tttctttttc aaaagctctc cctgagggaa tggataagaa gtggaacagg aataggagca
     6481 acaccatgca gttgaatggt tctcagatct ttgtagaggt cctgtgcgag cagggagtgg
     6541 acactctttt tggctacccc ggcggcgctg tgctgaacct ttacgacgag ctgtataaga
     6601 atgccgaccg catcacccat gtgcttaccg cccacgagca gggcgcagcc catgcagcgg
     6661 acggctacgc ccgcgccacc ggccgcaccg gcgtggtgct ggccaccagc ggcccgggtg
     6721 ccaccaatct ggtcaccggc attgcaaccg cctatatgga ctcggtgccc atggtggcct
     6781 ttaccggcaa cgtgcccacc agcagtatcg gcaaagacgg ctttcaggaa gcttacatcg
     6841 agggcattac ggtgcccatc acaaagcata acttcacggt gcgccgggta gaggacttgg
     6901 ctgacaccat gcgggcagcc ttccgcattg cgcagagcgg ccgcaagggc ccggtgctgg
     6961 tggatatccc caaggacgtg accgcagcag tgtgcgagtt cacccccaag cagccggagc
     7021 ccatccgcac cgtaactacc tataatgagg agcaggtgca ctgggcggca gacctcatca
     7081 acgccgcaca gcgcccgctg gtgtactttg gcggcggcgt gcgcagcgca gccagctgcc
     7141 agccgctgcg ggatctgctg cacaaggcgg agatccccgc cacctacacc ctgatggccg
     7201 caggcgttgt gccctatggc gacccgatga atctgggcat gctggggatg cacggctgct
     7261 acacctccaa ccgggcggtg gcagagtgcg atgtgctcat cgcggtgggt acccgcttct
     7321 ccgaccgtgt ggcgctgaac cccaagacct ttgccaaaaa cgccaccatc atccagatcg
     7381 acattgacgc cagcgagctg ggcaagaacg tggacgtgga tctttccatc gtgggcgatg
     7441 cagcctatgt gctgaacgcc atgctgcccc agatcaagcc cgccaagcac ccggactgga
     7501 tgacgatgat ccagagctgg caggcacagg attaccatcc tgtgtccgac cccacccggc
     7561 tgatgcccca tcaggtcatc ggcgaggtgt gcaaccagtg cggccccgac gccgtgtatg
     7621 ttaccgatgt gggtcaacac cagatgtggg cggcgcagta cctgcgccac accaagagcc
     7681 gtggctttat caccagcggc ggccttggca ccatgggctt tggctacggc gctgccattg
     7741 gtgcccagat ggcactggga cgccagcagc gtgtggtgat gtttaccggt gacgcctcct
     7801 tccacatgaa cctgaacgaa gcctgcaccg ccgtcagcta cgagctgccc atcatcacgg
     7861 tcatcttcaa taactcggtg ctgggcatgg tgcgccagtg gcagaccagc ttttacggca
     7921 agcgttacag ccagaccgac ccccaccgca agaccgattt tgtcaagctg gcagacggct
     7981 ttggcctgaa gggctaccgc tgcaccaatc tgccggagtt tcaggaagcc tttgcagatg
     8041 ccttgcagca gaaaggcccc acttggatcg agtgcatcat tgacaaggac gaaaaggtgc
     8101 tgcccatgat ccccggcggc ggcgatatca acgacatcat catggaataa ggaggacaca
     8161 gcatcatgaa atctgatcag cgcagggtca tcagcctgct ggtggacaac cagagcggcg
     8221 ttctggcccg ggtgtccagc ctgttctgcc gccgcggctt caatatcgac agccttacgg
     8281 tgtccgccac caacgacccg gcagtcagcc gcatcacagt gaccattacc agcgatgaaa
     8341 aggccttgca gcagctggta ttgcagaccg agcggctgga agtcacccgg caggtgttcg
     8401 tgctggacag cgaaaaagcg ctggagcggg agctgctgct gctcaaggtg gaatcggacg
     8461 tgcacaaccg cacagagctg cgggagatcg cctgcatcta caaggcaaag atcatcgatc
     8521 tttccccgga cagcatggtg tttgagttga tcggccggcc ggacaagctg gacgcatttt
     8581 tgaaaatgtt cgagggctac aacatccttg agcagtgccg caccggcgtt actgcactgg
     8641 agcgcggcgg gatgcaccag catatccaga agccgccgca ggaggtgcgc tccgtccagc
     8701 tgcccccgcc gggcgcaaga cgggcataat tacattgctt ttccgctcag ggtgagcgaa
     8761 agatagaaca gagcatacaa gaccggaaga taaaccaacc agttaatgta aaaggagact
     8821 aacgattatg gctatcaaga aatactacga ttccgactgc aacctcggcg tgctggacgg
     8881 caagaccgtc gctgtcatcg gcttcggcag ccagggtcat gcacactctg agaatctggc
     8941 tgagagcggc gtcaacgttg tggtcggcct gcgcaagggt tctgctcact gggcaaaggc
     9001 ttctgagttc gctgccaccc atgacaactt caaggtcatg gaggtggaag aggctgccaa
     9061 ggccggcgat gttgtcatga tgctggtgcc cgatgagctg tgcgccgata tctacaacac
     9121 ccaggttgct ccctacatga ccgagggcaa ggcactggcc tttgcacacg gcttcaacat
     9181 ccacttcaag accatcactg ctcccaagaa tgtggacgtt atcatgatcg ctcccaaggg
     9241 ccccggccac atcgtccgcc gcctgtacac cgagggcgag ggctgcccct ctctgatctg
     9301 cgtggagcag gactacaccg gtaaggccaa ggatatcgca ctggcttatg cttccggcat
     9361 cggcgcaggc cgtgcaggca ttctgcagac caccttcaag gaggagaccg agaccgatct
     9421 gttcggcgag caggccgtgc tgtgcggcgg tgtttccgag ctgatccacg ccggcttcga
     9481 tacgctggtg gaggccggct acgagcccga gatggcctac tttgagacct gccacgagat
     9541 gaagctgatc gttgacctga tcaacgaggg cggcttctcc aagatgcgct actccatctc
     9601 caacactgcc gagtacggcg actaccgcac cggcaagcgc ctgatcaccg aggagacccg
     9661 caaggagatg aagaaggttc tgaccgagat ccaggacggc acctttgctt ctgagttcct
     9721 gaccgagatg agccccaagg gcggccgcaa ggtgcacttc cttgccaagc gccgcatgga
     9781 ggctgagctg cccatcgaga aggtgggtgc tgagctgcgc agcatgatga gctggctgaa
     9841 gaagtaagag gagaaccctc tcagaccgct tttcggcggt cagctccccc gaaaggggga
     9901 gtttttgttg aaaagggaac cttatagctc ctccgcgaaa cctctccctc tcgggagagg
     9961 tggcacggcg caaccgtgac ggagagggct ttatcagaaa agaggatttg caatgagaag
    10021 tgacaacgtg accaagggct cggagcgcgc gcccaaccgc agcctgtttt atgcgctggg
    10081 ctacaccccg gaggaactgg agcgccccct catcggcgtg gtaagcgcct acagcgagat
    10141 cgtgcccgga cacatgaatc tggataagat cgccgaggct gtcaaggccg gtgtgcagat
    10201 ggccggtggt acccccatcc tgatccccgc catcggtgta tgcgatggca tcgctatggg
    10261 tcatgtgggc atgaagtact ctttggcctc ccgtgaactg atctgcgaca gcgtggagac
    10321 catgctgatg gcacaccagc tggacggcct tgtgctggtg cccaactgcg ataagatcgt
    10381 gcccggcatg gtgatggcag cggtgcgcat ggatgtgccc gccgtggtct gctccggcgg
    10441 ccccatgctg gccggtactt acggcggcga ggaagtgagc ctttccaaga tgttcgaggc
    10501 cgtgggtgcc tataaggccg gtatgatcac cgacgagcag ctggaggact gcacctgcaa
    10561 ctgctgtccc agctgcggca gctgctccgg tatgtacacc gccaacagca tgaactgcct
    10621 gtgcgaggcc atcggcatcg cactgcccgg caacggcacc atcccggctg tgtactccaa
    10681 gcgtctgcag ctggcaaagc acgccggtat ggccgtaatg gagatggtgc gcaagggcat
    10741 caccgcgcgc cagatcatca acgagcgctc catccgcaac gcactgacct gtgatatggc
    10801 gctgggctgc tccaccaaca cggtgctgca cctgctggct atcgcctacg aggccggtgt
    10861 gcctatcgac ctgaagctgt tcaacgagat cagcgccaag acccccaacc tgtgccatct
    10921 ggcaccggca ggtcccaccc atatgccgga tctgtacgca gcgggcggca tcccggcagt
    10981 acaggcggag ctggccaaga agggcctgct ggatctggat gtgcccaccg tcaccggcaa
    11041 gacccttggc gagaatatca agggtgccca tatcctgaac gaaaaggcca tccgtcccat
    11101 cgagaacccc tactctgaga ccggcggtct gcagatcctg tggggcaaca ttgccccgga
    11161 cggctgcgtt gtcaagcgca gcgctgtcgc cccggagatg cagcagcatt ccggcccggc
    11221 gcgggtgttc aacagcgagg aggaggccat tgccgccatc tacgcgggca agatcgtccc
    11281 gggcgatgtg gtggtcatcc gctacgaagg ccccaagggc ggcccgggca tgcgggagat
    11341 gctcaacccc acctctgcgc tggcaggcat gaagctggat aagacggtgg ccctcatcac
    11401 ggatggccgc ttctccggcg catcccgcgg tgctgccatc ggccatgtca gcccggaggc
    11461 ggcctccggc ggccccatcg gcctgatcga agaaggggat accatttcca ttgatatccc
    11521 caacgcctcc atcacgctgg aggtcagcga tgcagtgctg gccgagcgca aggcaaagta
    11581 cgttgcgccc gagcccaaca tcaagaccgg ctggctgagc cgttacgccc gcatggtcac
    11641 cagtgcaaat ctgggtgcag tgctgaaata aacgtaacga aagcgcctgt tgtgcggatg
    11701 cacaacaggc gcttttgtca ctctccgtat ttcatgagca tggcgcggac ggtgaggaag
    11761 atgatcttcc agtccaccca gaagctgcgc tcctggatgt atttcatatc cagcgccacc
    11821 cactcgtcaa agctcatctc gttacggtgg ggtgcaatct gccagtagca gctcagtccg
    11881 ggggtgacgt acagccgctg gcgctggtag tcgctgtaca gctctacctc ccggggcagt
    11941 gcggggcgcg gccccacgat gctcatatcg ccctgcagca cgttgagcag ctgtggcagc
    12001 tcgtccagac tggtcttgcg cagaaaacgt cccacccggg taatgcgggg gtcgcccttg
    12061 atcttgaaca ccgggccgtc catctggttc tggctcagca gctcattcag ctgctcctcg
    12121 gcgtccgggc acatggtacg aaacttatac agccagaaca gcttgccgtc ccgtcctacc
    12181 cgccgctgcc ggaaaatagc tccgtctccg gggctgtcca gcacgatggc aaggctgatc
    12241 agcagtgcca gcggcgcaag caggatcagc gccagcaggg agaatacgat gtcctgtgca
    12301 cgccgcagca cccagtaacg ccggtggctg cgcagcgtct tttcccggtc gatagaaatt
    12361 tgcggggcgg cgctgattgt tgactccatg caatgaccca ctcctgcctg taaaatgtgt
    12421 agaatcttta cattatttta acataaaaca ggacgcaatt caaccggatg aagcgcggcg
    12481 ggcgggggac agtaagcctg ctgaaaaaaa gtgaaaaaag gtggttgaca aaaccctttt
    12541 ctcatgctaa aataaacaag tcgtccggcg cacggatgca caacaactga atatgggcgt
    12601 gttcccgagt ggccaatggg gacagactgt aaatctgctg ctttcagctt cggtggttcg
    12661 aatccacccg cgcccaccaa acaagaaaaa tccgaacctg tttccgattg gagaagggtt
    12721 cggatttttc gttttcttcg ggtacaacaa cgaaggctcc cgtggacggc gcaaaacccc
    12781 gataccttgt cataggccgt aagacaatca caagatttgg agggtatgat tatgaagtac
    12841 gatgaaagag cctgcaagtt taatatagac actggctgtg tggagctgct gctccgggat
    12901 gggagaaaga tttccatcaa ttgcaccggg gtcgaggatg cgctggatgt gaccatggcg
    12961 cagcagacgg agctggatta ccttatttac aatgacccac tgggctatgc ggatttgatt
    13021 ctgaacggtg acccagagga atatttgaaa aatgcagccg ggagccatgg gttagaagat
    13081 taagggcaaa aaaataagag gtgtgcccaa ctggacacac ctcggtgaga tacatctata
    13141 taaggcaggg cgttcccttt actgggagcg tcctgctgtt tttatgctgc aacaggcaag
    13201 gcttgtagag cttcctgctc tttcagccat tcctcatatt cacgctggcc ttcctcgctg
    13261 ttgaaaaact caaccatgga gggataaaag caacgcgcaa gggtcttgat tgcttcatcc
    13321 gggtagccgg atttgttcga cttcttcttt ttgttcaaat ggtatcctcc gaaaatcaaa
    13381 gttccatatc ctgcccacgc ttgcggcttc gctgcggcac attcatggtg cgctcctgct
    13441 tgggagcaag aatcttttcc agaaaaccgc gcaccagttc aggagcacgg tggagagcat
    13501 ccagataggg ctttacatcg taccacaggt cgtggtactt gttgctccaa cgaacggcct
    13561 ccttcttggc ggtggaaagt tcttctttca ggcggcggtt ctccacgtcc atcatatagc
    13621 cgtggtcggc ttgctttttc agcttggaaa attcttcttc ggtcagcgag tagttaccga
    13681 gaaaggtgcg cttgccgata taatccagat cgcgcacatg aatgagggct tcttttgtga
    13741 gcgtggcctt tttctgcaca gcagcaagtt ccttttcggt cttggagagg gttttgttgg
    13801 tttgggtgag gtgctgctct ttctggtcaa tctgggcggt caggctgtcc agccgctcct
    13861 gctcccgctg gactttgaac tgggtgacgg tcaggtgttc ttcggtactg ccgcgctcgc
    13921 cgcgctctac atcggtatac ccagcattgt gcatatagtg gaagaaatcg tcttgcagga
    13981 cgctgtacga cttcttcagg actggcttgc cgttcttttg caacacaggc tttccggcat
    14041 cgtccagcag gggcttggat gcccacttct tgctccggc
//
