LOCUS       gnlProkkaACPGNNMH_181  10656 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ACPGNNMH_181.
ACCESSION   gnlProkkaACPGNNMH_181
VERSION     gnlProkkaACPGNNMH_181
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:01:36
            Original ID  :: gnl|Prokka|ACPGNNMH_181
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 7904
            Orig. end    :: 18560
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10656
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10258]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10258
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10656
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10656
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             4..990
                     /locus_tag="ctg181_8"
                     /transl_table=11
                     /translation="MQNKNKPLLLRPSGKDYLWGGSRLNDEFEKNIDLTPLAETWECST
                     HPDGPSYVVGGAFDGQELAEVLRAHPEYLGERHKGENTLPILIKFIDAKKDLSVQVHPT
                     DAYAQEHENGQLGKTEMWYVLDAGREARLVYGLKQNCTKAEMRRAIADGTVMKYLQKVP
                     IHKDDLFFIQAGTVHAIGAGALVAEIQENSNLTYRLYDYDRVGKDGKKRELHIDKALDV
                     ANLKSSAEPKQPLRVLKYRQGIASELLTRCKYFEVYRMIVNTERRQKVHYRADEIAFRV
                     LLCVNGCGTISYEGGNLPFYKGDCIFVPADSEVLTIHGQAQFLDVRG"
     CDS             996..2669
                     /locus_tag="ctg181_9"
                     /transl_table=11
                     /translation="MDIKKEYERWLANATADADVVAELKTLDDAKIEDAFYRDLAFGTG
                     GLRGVIGAGTNRMNVYTVAKASQGLADYLKKNFAEPSVAIGYDSRIKSDVFAKVAAGVF
                     AANGVKVNIWPTLMPVPTVSFATRYLHTSAGVMVTASHNPSKYNGYKVYGADGCQITTE
                     AAAEILAEIEKLDIFADVKTGDFEAGVADGSIQYIPDEVYTAFVEQVKNQSVLFGEEVN
                     KNVAIVYSPLNGTGLKPVTRTLKEMGYTNITVVKEQEQPDGKFPTCSYPNPEIKEAMAL
                     GMEYAKKCNADLLLATDPDCDRVGIAVKNKAGEYELLTGNQTGMLLLDYICSQRVKHGK
                     MPADPVMVKTIVTMDMGEQIATHYGLRTINVLTGFKFIGEQIGKLEQQGKADSYVFGFE
                     ESYGYLTGSYVRDKDGVDGAYMICEMFSYYATKGIGLLDKLDELYKTYGYCLNTLHSYE
                     FDGSAGFAKMQSIMQAFRGNIKEFGGKKVVELLDYAPGLDGLPKSDVLKFLLEDNCSIV
                     VRPSGTEPKLKTYISVSAEYKEAAEAVEAEICKSAEEFLK"
     CDS             3388..3717
                     /locus_tag="ctg181_10"
                     /transl_table=11
                     /translation="MPRTKGSKNKPKTVTADFATQIAEKQSAKETLTAEIASITANIDT
                     LKADLKEKKTALKKAEKEVATLEAKKAKADAKAAEEAKKAEAESVLKKLLAEGMSADEI
                     LEKLK"
     CDS             complement(3789..4343)
                     /locus_tag="ctg181_11"
                     /transl_table=11
                     /translation="MDSILIYQAANDLVQNTGTRNIKRIARSCSLDILETPRFKDVLGF
                     LSLHFDKPLILINRQLDKQTKQMVCGYALGHYLEHQLLMDLHTLNKFLTIKDKHILLYE
                     HNAFTSHLMLDSDEVYQMTKRGLDAVQISTAKRIHLNLVLVKLLELHHLGYDLRHYHAQ
                     HHAFIKQFNLPAHFQFDVAAG"
     CDS             complement(4389..4790)
                     /locus_tag="ctg181_12"
                     /transl_table=11
                     /translation="MKFGEKVRDLRKKHSLTQDELAKCLGVSKRTVIGWERDGRYPRNV
                     ETLEKMADIFHVPLTYIQPDQSLFIERAAATYGKKGKIEAQHLAFELTELFASGELTAQ
                     DMDGIMYEMHKAYFKYREQEREKNRILSL"
     CDS             5084..5290
                     /locus_tag="ctg181_13"
                     /transl_table=11
                     /translation="MSNGEHEIRTPKGLRIGNRSVVDGKNMLQIKRGGCEDYISAESLV
                     ERIHGLPVKSIEFITEEDQRKDA"
     CDS             5702..6349
                     /locus_tag="ctg181_14"
                     /transl_table=11
                     /translation="MLTLKKVKELVEAPVHTKRVPSPKVLLEEGLILMRKEFDHGSHLT
                     VYQSGYVLFSAGKRNTVFHIHDCCGDYAHDAAAGRGDVIKEEYFENCEWHIRALFEGER
                     KMEESQWKCEGAGQGNVCVSYHAVAEDWGEIADRTINVLEKIVEKEALHAMMEVLTKKQ
                     RRLIHQQFVLGKTHQEIADDMGISRGSVTRAVNQALERIRRKFDFETHYGCL"
     CDS             6666..6983
                     /locus_tag="ctg181_15"
                     /transl_table=11
                     /translation="MKLTFEEKKLLYTYGCADLELTHKRLCGVTGLTVDPDQNKLVLDF
                     CRKLEDETLADWYDQMFYFVRSEMEHYTMMQKMSRDIEEDEDWGPTIFDESKEEELIDD
                     V"
     CDS             6970..7182
                     /locus_tag="ctg181_16"
                     /transl_table=11
                     /translation="MTMFKLETMIYASEDGTNSVFTLNLALQKQLDTLASQHPEVCQRK
                     ARGEAGGVTYQVRGTALTVQPVRVS"
     CDS             complement(7410..7871)
                     /locus_tag="ctg181_17"
                     /transl_table=11
                     /translation="MKSKALSIVVLLLTVVLFGLLFVNQRQEQRQTAYMQQLQKEAMPY
                     EQEINDIRLELAQKQRAINIEEDTSGILFGFVPASADDFTEIDKLAAEHSITPVILLDC
                     SQEKEQLAQILEKAVAKDYEVVLAGLQIDESILQTADEMKDLLAQIGMI"
     CDS             complement(7868..9589)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 270.8; E-value:
                     4.1e-82)"
                     /gene_kind="transport"
                     /locus_tag="ctg181_18"
                     /transl_table=11
                     /translation="MKQKHTLQWLSAVTGRAKGLVGLLVVVQTVLSVSSIAFAFVLRRI
                     INMAVDGVRGGFWASLALLVGILLGQIVLSAAGRFLSEYTSATVENRFKHRLFSALLTG
                     DYASVAAVHSGEWMNRLTSDTTVVAGGVTQIVPGLIGMLVRLLGAVTAILWLEPRFLYI
                     LLPGGAAMMLLTYAFRKILKRLHKRIQETDGALRVFLQERLESLVIVRTFAKEEQMTRQ
                     ADALMDAHKAARMKRSNFSNLCNIGFAGAMDGAYLLGIGFCGYGILTGTMSYGNLMAIM
                     QLVGQVQSPFANLTGYLPRYYSMLASAERLMEAEAFAPDSTETVPEEQTLNFYQTELQS
                     LQLEHVCFTYQPPVQTKGEPPAMPVVLQDVSLTVRKGEYIAFTGPSGCGKSTLLKLLMC
                     LYPLDSGQRFLSTKTGNQPLTPAWKSLFAYVPQGNQLLSGSIRSIVAFGDEDRAQDENA
                     IYNALKIACADDFVRRLENGLDTVLGERGAGLSEGQMQRIAIARAVYSNHPILLLDEAT
                     SALDEATALRLLNNLRKMTDKTVILVTHRMNQAGFFDAELAFSKDGICVRERKTCK"
     CDS             complement(9586..10008)
                     /locus_tag="ctg181_19"
                     /transl_table=11
                     /translation="MPKLTLEESLAKNGFLTYRIRGVSMQPMLRQGRDLFTVVPKGAER
                     CKKYDVVLYRRPSDPYVLHRIIEVRPDSYVILGDNCIAKEYGIRDEDILGVLTSFQHNG
                     HTVSVSDWRYRLYSRGWVFFQPVRIFYKRVKGKLHR"
     CDS             complement(10001..10258)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg181_20"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.9e-11,
                     bitscore: 33.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.7e-14, bitscore: 43.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 1.6e-08,
                     bitscore: 25.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDTFVTQEMDGEQVMVEADGGFAGMVRSNATAAFIIDQLKTE
                     TTKEAILDAMCKKYDAPRAVMAEDVDMVLGNLKKIGALDA"
     CDS             complement(10322..10489)
                     /locus_tag="ctg181_21"
                     /transl_table=11
                     /translation="MEKYTKAQMEVIEFEAEDVITESIPIDHCPYDGGCKIEDLFCTPD
                     GDCASVLWGE"
ORIGIN
        1 gctatgcaaa acaagaataa gcctcttttg ctccgaccgt ccggcaagga ttatctttgg
       61 ggcggcagcc gtttaaatga tgaatttgaa aaaaatatcg acctgacccc gctggcagag
      121 acatgggagt gctccaccca ccccgatggt cccagctatg tggtaggcgg tgcctttgat
      181 ggacaggaac tggcagaggt gctgagagcg cacccggagt atctggggga gcgccataag
      241 ggcgaaaaca cgctgccgat cctcatcaaa ttcatcgatg ccaagaaaga cctgtcggtg
      301 caggtgcatc ccaccgatgc ctacgcacag gagcacgaga acggtcagct gggcaagacc
      361 gagatgtggt atgtgctgga tgccggacgc gaggcgaggc tggtctacgg actcaagcag
      421 aactgcacaa aggccgagat gcgcagggcg atcgcagacg gcacagtgat gaaatatctg
      481 caaaaggtcc ccatccacaa ggatgatctg ttcttcattc aggccgggac agtccacgcc
      541 atcggagcgg gtgcattggt ggccgaaatt caggaaaact ccaacctgac ctaccgcctg
      601 tacgattatg accgtgtggg caaggacggc aaaaagcggg agctgcacat cgacaaggcg
      661 ctggatgtgg cgaacctgaa gagcagcgca gagccgaagc agccccttcg ggtgctgaaa
      721 taccggcagg gcattgcctc tgagctgctg acccgctgca agtattttga agtgtaccgg
      781 atgatcgtca ataccgaacg gcggcagaag gtgcactacc gggcggatga gatcgccttc
      841 cgggtgctgc tctgcgtcaa cggctgcggc acgatctcct atgagggcgg caatcttccg
      901 ttctataagg gagactgcat ctttgtcccg gcggattccg aggtgctgac catccatgga
      961 caggcacaat ttctggatgt gagagggtaa acgatatgga tattaaaaag gaatacgagc
     1021 gctggctggc aaatgccacc gccgatgccg atgtagtggc agaactgaag acgctggacg
     1081 atgccaaaat cgaggacgct ttttaccgtg acctcgcctt tggcacgggc ggtctgcgcg
     1141 gcgtcatcgg cgcaggcacc aaccggatga acgtctacac cgtggcgaag gcctctcagg
     1201 gtctggccga ctatctgaag aagaactttg cagagccgtc ggtggccatc ggttacgaca
     1261 gccgcatcaa gagcgatgtg tttgcaaagg tggctgcagg tgtgttcgcg gccaatggcg
     1321 ttaaggtcaa catctggccg accctgatgc cggttcctac cgtgtccttt gcgacccgct
     1381 atctgcacac ctctgccggt gtcatggtga cggcgtccca caaccccagc aagtacaacg
     1441 gctataaggt ctacggcgcg gacggctgtc agatcaccac cgaggccgca gcagaaattc
     1501 tggctgagat cgagaagctg gacatctttg ccgacgtcaa gaccggcgat tttgaggcag
     1561 gtgtggcaga cggcagtatc cagtacatcc cggatgaggt ctacaccgca ttcgtggagc
     1621 aggtcaagaa tcagtctgtt ctgtttggcg aagaggtcaa caagaacgtg gctattgtgt
     1681 atagcccgct gaacggtacc ggcttgaagc ctgtgacccg caccctgaag gagatgggct
     1741 acaccaacat cacggtggtc aaggagcagg agcagccgga cgggaagttc ccgacctgct
     1801 cgtaccccaa cccggagatc aaagaagcta tggcgcttgg catggaatac gccaagaagt
     1861 gcaacgccga cctgctgctg gcgaccgacc ccgactgtga ccgtgtggga atcgccgtca
     1921 agaacaaggc aggggagtac gaattgctga ccggcaacca gactggtatg ctgttgctag
     1981 attatatttg cagccagcgc gtcaagcacg gcaagatgcc cgcagacccg gtcatggtca
     2041 agaccattgt caccatggat atgggcgaac agattgccac ccactatggc ctgcgcacca
     2101 tcaacgtgct gaccggcttc aagttcatcg gggagcagat cggcaagctg gaacagcagg
     2161 gcaaggccga cagctatgtg ttcggctttg aggagagcta tggctacctg accggctcct
     2221 acgtccggga caaggacggc gtggacggtg cctatatgat ctgcgagatg tttagctact
     2281 atgccaccaa gggcatcggc ctgctggaca agctggatga gctgtacaag acctatggct
     2341 actgcctgaa taccctgcac agctatgagt tcgacggaag cgccggtttt gctaagatgc
     2401 agagcatcat gcaggcattc cggggtaata tcaaggagtt tggcggcaag aaagtcgttg
     2461 aactgctgga ctacgctccg ggtctggatg gtctgcctaa gtccgatgtg ctcaagttct
     2521 tgctggaaga taactgctcc atcgtggtgc gcccctccgg taccgagccg aagctcaaga
     2581 cctatatctc tgtcagcgca gagtacaagg aagccgccga agctgtggaa gcagaaattt
     2641 gtaagagtgc ggaagagttc ttgaagtaaa tgtttacata caaagttttg ttaaaaagtc
     2701 catatgcaac attacggttg tccgacgcga ttactcgata taacgacaaa ccctctggcc
     2761 gcgctttatt ttgcgtgtgc tggagaaaat gacagtgatg gtgcaattta tatttttgct
     2821 gttaataagc gtgatgtgcg atatgccaat agtgatagag tccagatgct tgcaaccctt
     2881 gctgagttta gagcatctga acaagaattg ctttggaata ctgcctacga aaatgtggta
     2941 gagaataaat ttcctcagca gagtaacgga aaatatcgtg aaaaaatgtt tgaacaattt
     3001 taatatgcga taaaaaggca taatgctgca ttgaaaggga aattgttcca ttgaatcttc
     3061 ttacaccaca gttcgttcag ccgaatagag ataatccaag aattctaaaa caggatggag
     3121 catttattat atccggcttg gatgcgagtg ataaggaaag cgataataaa atacgtgaat
     3181 ttcttgttaa ggagctcata attccaaaag aagcaaagaa acagttaaga aaagaacttg
     3241 agtatgttgg aatcaatcaa gcatcgctct tcccagaagt tgataaagta gcagattatt
     3301 taagatgaat ggcttgagta gttgccgttt tttcataatg atgctatact aaacttggaa
     3361 ttatacataa ttcggaggtg tgcaacgatg cccagaacta aaggtagcaa gaataagccc
     3421 aaaactgtga ctgctgattt cgcaacgcag attgcagaaa agcagtccgc aaaggaaacg
     3481 ctcacagcgg aaatcgcatc tatcaccgcc aacattgaca ctttaaaggc tgacctgaaa
     3541 gagaagaaga ctgctctgaa gaaggccgaa aaagaagtgg caacgctgga agcaaaaaag
     3601 gcgaaggcag atgctaaggc tgcagaggaa gcaaagaaag cagaggcaga atctgttctg
     3661 aaaaagctgc ttgctgaagg catgagtgct gatgaaatcc tcgaaaaact gaaataacac
     3721 gaaaaacccg tgatggacag gcgtaacgcg ccgttcatta cgggttttag ggttataaga
     3781 acataagttc atccggcggc aacatcaaac tgaaaatgtg caggaagatt gaactgtttg
     3841 ataaacgcat ggtgctgggc gtgatagtgc cgtagatcgt atcccaaatg atgcagctca
     3901 agaagtttca ccagaaccag attgaggtga atccgtttgg ctgtagagat ttgcacagcg
     3961 tccaacccac gcttcgtcat ttgatagact tcatcactgt ccagcatcag gtgggatgtg
     4021 aaagcgttat gctcataaag aaggatgtgc ttatccttaa tggtcagaaa tttgttcagg
     4081 gtatgcaagt ccataagcag ctgatgctcc agataatgac cgagcgcata gccgcacacc
     4141 atctgcttcg tctgtttgtc caactggcga ttgataagaa tcaatggctt atcaaagtgg
     4201 agtgaaagaa aacccagcac atctttgaag cgaggtgttt caaggatgtc caggctgcag
     4261 cttcgcgcaa tccgtttgat gttgcgggtg ccggtatttt ggacgaggtc attggcagct
     4321 tggtaaataa gaatggaatc cataatgtgc tctcctttcg aggatggcat agtgaatgga
     4381 acggaatttt acaggctcaa tattcggttc ttttctcgtt cttgctcgcg gtacttaaaa
     4441 taggctttgt gcatttcata catgatgccg tccatatcct gcgcggtcaa ctctccgctg
     4501 gcaaaaagct cagtaagctc gaatgcgaga tgctgggctt ctattttgcc tttttttccg
     4561 taggttgctg cagcgcgttc aatgaataaa gactgatccg gttgtatgta ggtcagaggc
     4621 acatggaata tatcggccat tttttcaagt gtttcaacat tgcgagggta gcgaccatca
     4681 cgttcccatc cgatgactgt tcgtttgctg acacccagac actttgccaa ttcgtcctgt
     4741 gttaaggaat gcttctttcg taaatcacga actttctctc caaatttcat gtttgcaacc
     4801 tttctatgga gcagttatcg tactgtaaca atgtgcaacg gaatttgtaa atattcaatt
     4861 cagaatgtgc aataaaattt cacattttcc tcttgacacc gcaacactac ttgcatataa
     4921 tatatgctat attctttcaa cttttatggc tattatactg gaaaatgcgt aaatatgcaa
     4981 gtgaaaaaga tgaaattcaa gaaaagttca gaaaagtcca taagttgaaa tcgaatgaac
     5041 gaaaaggtga aattcaaacc agaaaaagga ggccgtgaaa aagatgagta atggagaaca
     5101 tgagatccgc actccgaagg gattgcggat tggaaatcgc agtgtcgttg atgggaaaaa
     5161 tatgcttcag atcaagcgtg gaggctgtga agattacatt tctgctgaat ctctggtgga
     5221 gcgcattcac ggtctgcccg tgaagagtat cgagtttatc acagaggagg atcagcgaaa
     5281 agacgcctga agcagaatcc ttcatcggac actgagagtg cagaggtgga agtttaggcg
     5341 gcacttagtt agccgaccag ctccatcaga tgttcttttg ggtctacaat ataatatctg
     5401 tttgtttaga gcgataccgt agcaatatgt gatattggcc ggaacagaat gagcgaaagc
     5461 agcgcagaag tgcgcctgca agtagttcat cctgttccgg ccttttttgt ttttcaaaaa
     5521 atatttttaa aactgtattc caaaatgccc ctgcggattc ctattagtat agggacttcc
     5581 caaaagtaga aagcagcaag aggaatctta gattcccgtt taaaaaaaac gggtgaatct
     5641 gagacgattt ctgctgcttt tttcagttca cccggagccg aacggcagaa aggtggacaa
     5701 aatgcttaca ttgaaaaagg tcaaggaact ggtagaagca cctgtacata ccaagcgcgt
     5761 accttctccg aaggtgcttt tggaagaagg tctgattctg atgcgtaaag aatttgatca
     5821 tggcagtcat ctgacggtct atcaaagcgg ctacgttttg ttctctgccg gaaagagaaa
     5881 caccgtgttt cacattcacg actgctgtgg ggattatgcc catgatgcag cggcggggag
     5941 aggcgatgtg atcaaggagg aatactttga aaactgcgag tggcatatcc gcgcactgtt
     6001 tgagggtgaa cggaaaatgg aagaatccca gtggaaatgc gagggagcag gtcagggtaa
     6061 tgtgtgcgtt tcgtatcatg ctgtggcgga agattggggc gagattgcag accgcacgat
     6121 caatgtgctg gagaaaatcg ttgagaagga agcacttcat gcaatgatgg aggttctgac
     6181 gaagaagcag cgcaggctga tccatcagca gttcgtcctc ggtaagaccc accaggaaat
     6241 tgcagatgat atgggaatct cgcggggatc ggttacaagg gcggtcaacc aggctcttga
     6301 gcggattcgc cgcaaatttg actttgaaac acattatgga tgtctatgaa ttttacggat
     6361 agttcctttg aacgaatgat gcgccagcgt ccgggaacgg acagtggcca tccctgcaag
     6421 caccgccgcc acaaatggga gtgtggctat ctgctgcacc agtgccgcaa gaagtttcgc
     6481 tcggttctgg gcgataccgc accgcctgca gccggggcag tccgcccctg atgcagcggg
     6541 aagggaggtg agcaaccgtg caggaagaag tcactgagaa aaccatcgcg ctatgtatca
     6601 aaggaggaaa aatcaccgca cagattttga aagcaggccc ttttttaata cggaggtaca
     6661 agcctatgaa actgacgttt gaagaaaaaa agctgctcta cacctatggc tgcgccgatc
     6721 tggaactgac tcacaagcgg ctgtgcggag ttaccgggct gacggttgac cccgaccaga
     6781 acaagctggt gcttgacttc tgccggaagt tggaggacga aacactggca gactggtacg
     6841 accagatgtt ctactttgtc cgttccgaga tggagcatta taccatgatg cagaaaatgt
     6901 cacgggacat cgaggaggac gaggactggg ggccgaccat ctttgacgaa tccaaggagg
     6961 aagaactgat tgacgatgtt taagctggaa accatgatct acgccagcga ggacggaaca
     7021 aacagcgtgt tcacgctgaa tctcgccttg caaaagcagc tggataccct tgcatcgcag
     7081 cacccggagg tgtgccagag gaaagcaagg ggcgaagctg gcggggtgac gtatcaggtc
     7141 aggggcactg cgctgactgt ccagccggtg cgggtatcct gaaagcgata cccgatctgc
     7201 tatggtagaa taaagaacaa cgggcaaagc gtcgggaggg atgctttgcc cgttttacat
     7261 acctgtatgc aattatgcgg aacttttaga gcagtgatgg ctgctcatcc agacaaagag
     7321 cattgaagcg gcgaaaaaac acgggcatcc gtcttggttg cccgcgcata aaaagaatga
     7381 tacacagaag gagggtgcac gggtgttctt tatatcatgc ctatctgcgc caacaggtct
     7441 ttcatctcgt ccgctgtctg caaaatggat tcgtcaattt gcaggcccgc caacacaact
     7501 tcatagtctt ttgcaacggc tttttccaaa atctgggcca gctgttcttt ttcctgcgaa
     7561 cagtccagaa ggatcaccgg ggtgatggaa tgttctgcag ccagtttatc gatctcggta
     7621 aaatcgtccg ccgatgcagg aacaaaacca aaaaggatgc cggaagtatc ttcttcaatg
     7681 ttgatggcac gttgcttttg tgcaagctcc aaacgaatat cgttgatctc ttgctcatat
     7741 ggcattgctt ccttttgaag ctgctgcata tacgctgtct gccgctgttc ctgacgttgg
     7801 tttacaaaga gcagtccgaa cagcacgaca gtaagaagaa ggactacgat cgataatgct
     7861 ttgcttttca tttgcacgtt ttcctttccc tcacgcaaat gccatccttc gagaacgcca
     7921 gttctgcatc aaagaacccg gcctgattca tccggtgcgt gaccagaatc accgttttgt
     7981 ccgtcatctt tcgcaaatta ttcagcagtc gaagggctgt tgcttcgtcc aatgcgctgg
     8041 tcgcctcgtc caacagcaga attggatggt tggaatatac cgcccgggca atggcgatgc
     8101 gctgcatctg cccttcggac agacctgcgc cgcgctcacc cagcacggta tctagcccgt
     8161 tttccagcct gcgtacaaaa tcatccgcac aggcgatttt cagtgcgtta taaattgcat
     8221 tctcatcctg cgccctatct tcatccccaa atgcaacaat gctgcggatg gaaccggaca
     8281 aaagctggtt cccctgcggc acataggcaa acagactttt ccatgctggg gtcagcggtt
     8341 ggttcccggt tttcgtggaa aggaaccgct ggccggaatc cagcggatac aggcacatga
     8401 gcagtttgag gagggtgctt ttgccgcagc cggacggccc ggtgaacgcg atgtactcgc
     8461 ccttgcggac ggtcagactg acatcctgca aaaccaccgg catggcgggc ggttcgccct
     8521 tggtctgcac cgggggctga taggtaaaac agacatgttc cagctgaagg gactgcaatt
     8581 cggtctgata aaaattcaag gtctgttctt caggcaccgt ttcggtgctg tctggcgcaa
     8641 aggcttccgc ttccatcagg cgctcagcgc tggccagcat ggaataatac cgcggcagat
     8701 accccgtcag gttggcaaac ggactttgca cctgccccac cagctgcata atggccatca
     8761 ggttgccgta gctcatggta ccggtcagga tgccgtatcc gcaaaagccg atgcccagca
     8821 gatacgcccc gtccatggca ccggcaaagc cgatgttgca caggttggaa aaattgctgc
     8881 gcttcatccg ggcggctttg tgggcgtcca tcagggcgtc tgcctgccgc gtcatctgtt
     8941 cttccttggc aaaagtgcgg acgatgacaa gactttccag ccgctcctgc aagaacaccc
     9001 ggagcgcacc gtctgtttct tgaatcctct tgtgcagtcg tttcaatatc ttgcggaacg
     9061 cataggtcag cagcatcatg gccgcgccgc cagggagaag gatgtacaaa aaacgcggct
     9121 cgagccacaa aatagcggtc actgcgccca gcaagcgcac cagcattccg atcagcccgg
     9181 gcacgatctg ggtcacgccg cccgctacca cggtggtatc cgaggtcagg cggttcatcc
     9241 actcgccgga gtgcaccgcc gccactgacg cataatcgcc ggtaagcagg gcggagaaga
     9301 gccggtgctt gaagcggttt tccacagtgg cgctggtgta ctcactcaaa aaacggcccg
     9361 ccgcgctcaa cacgatctgc cccagcagga tgcccaccag cagcgccagc gatgcccaaa
     9421 aaccgccccg tactccgtcc acggccatgt tgatgatgcg ccgcagtaca aacgcaaagg
     9481 cgatgctgga aacgctcagc acggtctgca ccactaccag cagccccacc agccctttgg
     9541 cacggccggt gacggcgctg agccattgca gggtatgttt ctgtttcatc ggtgcagttt
     9601 tcctttcaca cgcttgtaga agatgcgcac cggctgaaaa aagacccagc cacggctgta
     9661 aagccgatac cgccagtcgg acacggacac cgtatggccg ttgtgttgga aagaagtcag
     9721 cacgcccaaa atgtcctcgt cccggatgcc gtattctttt gcaatgcagt tgtcacccag
     9781 aatcacatag ctgtccgggc gcacttcaat gatgcggtgc agcacatacg ggtcagacgg
     9841 cctgcggtac agtaccacgt catatttttt gcagcgttcc gcgccttttg ggactacggt
     9901 aaacaggtct cgcccctgcc ggagcatcgg ctgcatactt acgccccgga tgcggtaggt
     9961 caaaaagcca tttttcgcaa ggctttcttc caatgtaagc ttaggcatcc agcgcaccaa
    10021 tttttttcag gttgcccagc accatatcca catcctcggc catcacagcg cggggggcat
    10081 cgtacttttt gcacatggcg tccagaatgg cttccttggt ggtttcggtt ttgagctggt
    10141 cgatgataaa ggcggcggtg gcattgctgc gcaccatgcc ggcaaagccg ccgtccgctt
    10201 ccaccatcac ctgctcgccg tccatctcct gcgtcacaaa ggtatctttc agtttcatat
    10261 cgtgtcgtcc tttcttccat accaaaagaa ggcaggcagc caaaaactgc ctgcctttga
    10321 attactcacc ccacagcacg ctcgcacagt caccgtccgg agtacagaag aggtcctcaa
    10381 tcttacaacc gccatcgtag gggcagtgat caatcggtat gctttccgtg atgacatctt
    10441 cggcctcaaa ctcgatgact tccatctgag ccttggtata cttttccatt ggtttttccc
    10501 tcctttcgtg agaagattct ctatgtgaag cagtttttac accgcatcac gcgaaagaag
    10561 gggttgacag aaaaccgggc tcaggacata atttaacttg cttgcttgct tgcttgcttg
    10621 ctaagcatta tcgctgtttg cttcataaag tcaagt
//
