LOCUS       c00199_gnlPro..         9363 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKOAMGFB_199.
ACCESSION   c00199_gnlPro..
VERSION     c00199_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:19:52
            Original ID  :: gnl|Prokka|AKOAMGFB_199
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9363
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9363
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2670:9362]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2671..9362
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..9363
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9363
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..890
                     /locus_tag="ctg199_1"
                     /transl_table=11
                     /translation="KVSTKDLGEVGDMITNLIGELKSFDANEEQQKGIMGFFKKKTSQL
                     DALKTKYDKTETNVEKIQSMLEAHQVQLLKDIAMLDKMYELNMAYFKELSMYILAGKKK
                     LADVRANELQQAMDKAKVSGLPEDAQAARDLADQCERFEKKLYDLELTRNISLQMGPQI
                     RLLQNNNTMMAEKIQSTIVNTIPLWKNQMVLALGLAHSQQAMQAERAVTNMTNDLLKKN
                     AEALKLGTIETAKESQRGIVDIETLQQTNKSLIETLDELNKIQSEGRAKRAAAEQELTR
                     IEDELKTKMMEIRS"
     CDS             892..1650
                     /locus_tag="ctg199_2"
                     /transl_table=11
                     /translation="MANADFSQNKQTAPGGFDAGSYREKAKPEQAVTLTPRQQKLAALE
                     AKLPAALSTRAAALALSVVVMLAAFFGFGSAKLRGKYNTARQWFTAGVAADNGYNLSEE
                     LTTRENTAANILTTASNTLGADSAEVLAAQTALNDFSACLQAVQNGGKSQTLTSLPYYQ
                     GSTMHALYQADQALGTAIDQLYAKLQEQAADPMKMGAVQGQYGQFNSAATIIGTLQYNT
                     AVYEYQKDVGGFPASVLGALSGVKEVEPFA"
     CDS             1647..2528
                     /locus_tag="ctg199_3"
                     /transl_table=11
                     /translation="MKNFAKRISALVLAVVVSAAVLCPAAFAAQLPSLPKGECVVDDAG
                     VLSSSTVQTITELNAQLESSCSGAQIGVLTVEYTGNDSTEDYAVQAANAWGIGSSTGKN
                     GVLILLVMETQQYADGDYYIATGDGFRNTTLEKQASAIAQTMEDQFAAKDYDGAVTTCA
                     RNVANTIADIYGVSLSGSAGNGSTVQPGHQGSQSSGGSALTDILTLVVSVVLLIVIIRS
                     VAYVFASPCGWLWCFGGPRPPRGGGFGGMGGGSFGGGAGRGGFGGGSFGGGGSFGGMGG
                     GSFHGGGGGRGR"
     CDS             2671..3876
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg199_4"
                     /sec_met_domain="PALP (E-value: 2.6e-94, bitscore: 305.1,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLDKIYHAAFVLKDVARKTDLIEAPKLSKDCQLYLKTENLQAT
                     GSFKVRGAYYKISQLSEEESAKGVIACSAGNHAQGVALAATRRGIRSIVCMPDGAPLMK
                     VENTKNLGAEVCLVPGTYDEAHDKAVQLQKEYDMTFIHPYDDEQVIAGQGTIGLEILDQ
                     LPDVDAVVVPVGGGGLISGIAFAIKTLRPEVKVYGVQAEGAPSMYRSLHEHKYQTLKSA
                     STFADGIQVKTPGELTYQLCEQYVDDIVTVTEDETAAAILSLMENQKLVAEGAGAVPVA
                     AVLFHKLPVEGKKVACVISGGNIDVNILNRVITRGLVMSGRKANLTIALEDKPGQLKKV
                     AEVVSRCGSNVVSVQHDGSDPNMPISSCFLKLTLETRDAAQIEQIRTELTKAGFQLVSE
                     RV"
     CDS             4064..4438
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ribonuc_L-PSP"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1038:Endoribonuclease L-PSP (Score: 149.8; E-value:
                     1.2e-46)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg199_5"
                     /sec_met_domain="Ribonuc_L-PSP (E-value: 1.7e-47, bitscore:
                     149.8, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVSTANAPAAIGPYSQALDLGNMVFVSGQLPVDPATGTMADTV
                     EQQAAQSLANLKAILAEAGLSMNNVVKTVIFLADINDFAAVNAEYAKAFAEPFPARSCV
                     QVAAIPKGAKLEIECIAVRD"
     CDS             complement(4526..5743)
                     /locus_tag="ctg199_6"
                     /transl_table=11
                     /translation="MKLREWNAHLHGLVVFRALLNDPVVAKLLDLTDRMEAGCSSYGPV
                     CDAVAAFEAALFEYTTNWGSYLSNAVLEAETICVRQAAAGQLDALLQSALDSELQFLQQ
                     LCGLTLDELFQTAYSEQAQRPELAFLPRWQTCELDLAAAYAQRMSEVGKKGYGMFAKHH
                     VFTVENGQLVPVKYPDPQRLSELPGYEKEREKVIANTKALLAGMPANNVLLYGDAGTGK
                     SSAVKAIANEFAPEGLRLVEVKKNQLYQIPDLMDKLAANPLKFILFIDDLSFTANDDNF
                     AALKAILEGSVGGRAQNIAVYATSNRRHLIKETLSDRTGDDIHEADTRQELMSLSARFG
                     LTVTFQRPEKARFETILEELAKQHNIQMPTEQLLLKAEAFALRAGGRSPRVAKQFIEQC
                     EAGVQK"
     CDS             6270..7934
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg199_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-51, bitscore:
                     163.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLNGSQIFVEVLCEQGVDTLFGYPGGAVLNLYDELYKNADRITH
                     VLTAHEQGAAHAADGYARATGRTGVVLATSGPGATNLVTGIATAYMDSVPMVAFTGNVP
                     TSSIGKDGFQEAYIEGITVPITKHNFTVRRVEDLADTMRAAFRIAQSGRKGPVLVDIPK
                     DVTAAVCEFTPKQPEPIRTVTTYNEEQVHWAADLINAAQRPLVYFGGGVRSAASCQPLR
                     DLLHKAEIPATYTLMAAGVVPYGDPMNLGMLGMHGCYTSNRAVAECDVLIAVGTRFSDR
                     VALNPKTFAKNATIIQIDIDASELGKNVDVDLSIVGDAAYVLNAMLPQIKPAKHPEWMK
                     MIQSWQAQDYHPVSDPTRLMPHQVIGEVCNQCGPDAVYVTDVGQHQMWAAQYLRHTKSR
                     GFITSGGLGTMGFGYGAAIGAQMALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIIT
                     VIFNNSVLGMVRQWQTSFYGKRYSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFA
                     DALQQKGPTWIECIIDKDEKVLPMIPGGGDINDIIME"
     CDS             7950..8513
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg199_8"
                     /sec_met_domain="ALS_ss_C (E-value: 1.2e-28, bitscore:
                     88.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDSEKALERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHIQKPPQEVRSVQLPPPGARRA"
     CDS             8613..9362
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg199_9"
                     /sec_met_domain="IlvN (E-value: 2e-75, bitscore: 241.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 5.9e-34, bitscore: 106.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHDNFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVSELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGF"
ORIGIN
        1 ccaaggtgtc caccaaggat ctgggcgagg tgggcgatat gatcaccaac ctcattggcg
       61 agctgaagag ctttgatgcc aacgaggagc agcagaaggg cattatgggc ttcttcaaga
      121 agaaaaccag ccagctggat gccctcaaga ccaagtacga caagaccgag accaacgtgg
      181 aaaagatcca gtccatgctg gaagcccatc aggtgcagct gctcaaggat atcgctatgc
      241 tggacaagat gtacgagctg aacatggcct acttcaagga actgagcatg tatatccttg
      301 ccggcaagaa aaagctggct gatgtgcgtg ccaacgaatt gcagcaggct atggacaagg
      361 ccaaggtctc cggtctgccg gaggatgcac aggccgcccg cgaccttgcc gaccagtgcg
      421 agcgctttga gaaaaagctg tatgatctgg agctgacccg caacatcagt ttgcagatgg
      481 gcccacagat ccgtctgctg cagaacaaca acaccatgat ggcggaaaag atccagtcca
      541 ccatcgtcaa caccatcccg ctgtggaaga accagatggt gctggcactg gggctggcac
      601 acagccagca ggccatgcag gccgagcgcg ccgtgaccaa catgaccaac gacctgctga
      661 agaagaacgc cgaggcgctg aagctgggca ccattgagac tgccaaggag agccagcgcg
      721 gcatcgtgga tatcgagacg ctacagcaga ccaacaagag cctaatcgag acgctggacg
      781 aactgaacaa gatccagagc gagggccgcg caaagcgcgc cgccgccgag caggagctga
      841 cccgcatcga ggacgaactg aaaaccaaaa tgatggagat ccggagctga aatggcaaac
      901 gctgattttt ctcagaacaa acaaaccgct cccggcggct ttgacgcggg cagctaccgc
      961 gaaaaagcaa agccggagca ggccgtaacg ctgaccccgc gccagcagaa gctggccgca
     1021 ctggaagcaa agctgcccgc tgcgctttcc acccgggcgg cggcgctggc tttgagcgta
     1081 gtggtgatgc tggcggcttt ctttggcttt ggcagcgcca agctgcgcgg caagtacaac
     1141 accgcccgcc agtggttcac cgcaggggtc gccgccgaca atggctataa cctgagcgag
     1201 gaactgacca cccgggagaa cacggccgca aatatcctca ccaccgcctc caacaccctt
     1261 ggtgcagaca gcgccgaggt gctggccgca cagacggcgc tgaatgattt ctccgcttgt
     1321 ctgcaagcgg tgcagaacgg cggcaaaagc cagacgctga cctcgctgcc ctattatcag
     1381 ggcagcacga tgcacgcgct gtatcaggcc gatcaggcac tgggcactgc catcgaccag
     1441 ctgtatgcaa agttgcagga gcaggccgcc gaccccatga agatgggcgc ggtgcagggg
     1501 cagtacggtc aattcaacag cgcagccacc atcatcggca ccttgcagta caatacggcg
     1561 gtgtatgaat atcaaaagga cgtcggcggc ttcccggcca gtgtgctggg agctttgtcc
     1621 ggcgtaaagg aggttgagcc cttcgcatga aaaactttgc aaaacgcatc agcgcactgg
     1681 tgctggccgt ggtggtcagt gcggcggtgc tgtgcccggc ggcctttgct gcccagctgc
     1741 ccagcctgcc caagggcgag tgtgtggtgg acgatgccgg tgtgctgagc agcagcaccg
     1801 tgcagaccat caccgaactg aacgcccagc tggaatccag ctgcagcggc gcacagatcg
     1861 gtgtactgac agtagaatac acaggcaatg attccacaga ggattacgct gtgcaggcgg
     1921 ccaatgcctg gggcattggt tcttctaccg gcaaaaatgg tgtgctgatc ctgttggtaa
     1981 tggagaccca gcagtacgcc gacggcgatt actatattgc cacaggtgac ggcttccgca
     2041 acactacctt ggaaaagcag gccagcgcca ttgcccagac catggaagat cagtttgccg
     2101 caaaggatta tgacggcgca gtgaccacct gtgcccggaa tgtggcaaac accatcgcag
     2161 atatttacgg ggtcagcctt tccggcagcg ccggcaacgg cagcaccgtg cagcccgggc
     2221 atcagggcag ccagagcagc ggcggcagcg ccctgaccga catcctgacc cttgtggtca
     2281 gcgttgtgct gctcatcgtc atcatccggt cggtggccta tgtttttgcc agcccctgcg
     2341 gctggctgtg gtgcttcggc gggccccggc ctccgcgcgg cggcggcttt ggcggcatgg
     2401 gcggcggctc cttcgggggc ggtgccgggc gcggtggttt cggcggcggc agttttggcg
     2461 gtggcggctc cttcgggggc atgggcggcg gcagcttcca cggcggcggc ggtggccgtg
     2521 ggcggtaatg agaataaaaa gagaaaggcg gtggctttac cactgccttt ctctttttta
     2581 cgccttttat cgtgaatgga attcatttga caaaacaatt tttgtaactt atactggatg
     2641 acatcacgaa aaataaagga agtatctgtc atgctgactc tggataagat ctaccacgcc
     2701 gcctttgtgc tgaaggacgt agcgcgcaag accgacctca tcgaagcccc caagctgtcc
     2761 aaggactgcc agctgtacct taagaccgag aacctgcagg ccaccggcag ctttaaggtg
     2821 cggggcgctt actataaaat cagccagctt tccgaggagg agagcgccaa gggcgtcatt
     2881 gcctgctctg cgggcaacca tgcgcagggt gtggcgctgg cggctacccg gcgcggcatc
     2941 cgcagcatcg tctgtatgcc ggacggcgca cccctgatga aggtggaaaa caccaaaaat
     3001 ctgggcgcgg aggtctgcct tgtgcccggc acctacgacg aagcccacga caaggccgtg
     3061 cagctgcaaa aggagtacga catgaccttt atccacccct acgatgacga gcaggtcatc
     3121 gccgggcagg gtaccatcgg cttggagatc cttgaccagc tgccggatgt ggacgctgtg
     3181 gtggtgccgg tgggcggcgg cggactgatc tccggcattg cctttgccat caagaccctg
     3241 cgcccggagg tcaaggtgta cggcgtacag gccgagggtg cccccagtat gtaccgcagc
     3301 ctgcacgagc acaagtacca gaccctgaaa tctgcttcca cctttgcgga cggcattcag
     3361 gtcaagaccc cgggcgagct gacctaccag ctgtgcgagc agtatgtgga cgatatcgtc
     3421 accgtgaccg aggacgagac ggcggcggcc atcctctccc tgatggagaa ccagaagctg
     3481 gtggccgagg gtgcaggcgc tgtgccggtg gcggcggtgc tgttccacaa gctgccggta
     3541 gagggcaaaa aggtggcctg cgtcatctcc ggcggcaaca ttgatgtgaa tatcctgaac
     3601 cgcgttatca cccgcggcct tgtgatgagc ggccgcaagg caaatctgac catcgcactg
     3661 gaggacaaac ccggccagct gaaaaaggtg gccgaggtgg tgtcccgctg cggcagcaac
     3721 gtggtgtcgg tgcagcacga tggctccgac cccaatatgc ccatttccag ctgcttcctc
     3781 aagctgacgc tggagacccg cgatgccgcc cagatcgagc agatccgcac agagctgacg
     3841 aaggccggtt tccagctggt cagcgagcgg gtgtaaactt catcgtttgc aagagtgaaa
     3901 accttccccc ggacggggga aggtggatgc gaacggagtg agcagacgga tgagggcaca
     3961 ggcaagcagc ggcttacggg aaattacccc ctcatctggc tctatccgaa gaaaaaagcg
     4021 aatttgttct aaacctgatg taatataaag gagaaaatat accatgaaag tcgtatctac
     4081 cgccaacgca cctgccgcca tcggccctta cagtcaggca ctggatctgg gcaatatggt
     4141 gtttgtttcc gggcagctcc cggtagaccc cgccaccggc accatggccg ataccgtgga
     4201 gcagcaggcc gcacagagcc ttgccaacct gaaagcgatt ctggccgagg cggggctttc
     4261 catgaacaac gtggtcaaga cggtgatctt tctggccgac atcaacgatt ttgccgcagt
     4321 gaacgcagag tacgccaagg cctttgccga gccgttcccc gcccgcagct gcgtgcaggt
     4381 ggcagccatc cccaagggcg caaagctgga gattgagtgc atcgccgtgc gggactgagc
     4441 gaataaagat aggaaaaacg ggacgccgaa gcatctgcgg atgctttggt gtcccgtttt
     4501 ttgataacgc ttaaaactgg tgcatttact tctgcacccc ggcctcgcat tgctcgatga
     4561 actgcttggc cacccggggg ctgcggccgc cggcacgcag ggcaaaggcc tcggccttga
     4621 gcagcagctg ctcggtgggc atctggatgt tgtgctgctt tgccagctcc tccagaatgg
     4681 tctcgaaccg tgccttttcc ggccgctgga aggtgaccgt caggccgaac cgggcggaaa
     4741 ggctcatcag ctcctgccgg gtgtcggctt cgtggatgtc gtcgccggtg cggtctgaga
     4801 gagtctcctt gatgaggtgg cggcggttgg aggtggcgta caccgcaatg ttctgggcac
     4861 ggccgcctac gctgccctcc aaaatggcct tcagggcggc aaagttgtcg tcgttggcgg
     4921 taaagctcag gtcgtcgatg aacaaaatga acttgagcgg gtttgccgcc agcttatcca
     4981 tcaggtcggg gatctggtac agctggttct tttttacctc taccagccgc agtccctcgg
     5041 gcgcaaactc gttggcaatg gcctttaccg cgctggattt gccggtaccg gcgtcaccgt
     5101 acagcagcac attgttggcg ggcatcccgg ctagcagtgc ctttgtgttg gcgatcacct
     5161 tttcccgctc cttctcgtag cctggcagct cggaaaggcg ctgcgggtcg gggtatttta
     5221 ccggcacaag ctggccgttc tccaccgtga atacatggtg ctttgcaaac ataccgtagc
     5281 cctttttgcc cacctcgctc atgcgctggg cgtaggcggc ggcaaggtca agctcacagg
     5341 tctgccaccg gggcaggaac gccaactccg gccgctgcgc ctgctccgag taggcggtct
     5401 gaaacagctc gtccagcgtc agcccgcaca gctgctgcaa aaactgcagc tcgctgtcca
     5461 aggcgctttg cagcagcgcg tccaactgcc cggcagcggc ctgccgcaca cagatggtct
     5521 cggcctccag cacagcattg ctcaggtagc tgccccagtt ggtggtgtac tcgaacagcg
     5581 cagcctcaaa ggcggctacg gcatcgcaca ccgggccgta ggaggagcag cctgcctcca
     5641 tgcggtcggt caggtctaaa agctttgcca caacagggtc gttcagcagg gcgcggaaca
     5701 caacaagccc atgcagatgg gcattccatt ctcttaattt cataggttga tcccttttcc
     5761 tctccattgg cacataccct acaaaacgca ggtacgcgga tatcaaaagt atacagcggt
     5821 tcaggtgtgg atgcaagagg tgttaaaaat gcttcatctt tgggctgatt caggttacaa
     5881 attgtcgatt gacaaaagcc cggtttatag tataatttac atcaacaaat gcgcagatgg
     5941 gaaaaagtac cacacgatcc ccactgttca gagagctgcc gtctggtgca aggcagtcag
     6001 cgtttcgtgc ggaaaatcat cccggagcag cctgcccaac gggtgcaaaa cccttgtaag
     6061 cagcgccggt tgcagccgtt accgtgcagg gctttgttgg aagcccgtga gagggtgtgc
     6121 acagcacgcc aacgagagtg gtaccgcaga gagcttgatg ttacaaggtc tttgtctctt
     6181 gaagaaagca ggggacaagg gctttttctt tttcggaagc tctccctgag ggaatggata
     6241 agaagtggaa caggaatagg agcaacacca tgcagttgaa tggttctcag atctttgtag
     6301 aggtcctgtg cgagcaggga gtggacactc tttttggcta ccccggcggc gctgtgctga
     6361 acctttacga cgagctgtat aagaatgccg accgcatcac ccatgtgctt accgcccacg
     6421 agcagggcgc agcccatgca gcggacggct acgcccgcgc caccggccgc accggcgtgg
     6481 tgctggctac cagcggcccg ggtgctacca atctggtcac cggcattgcc accgcctata
     6541 tggactcggt gcccatggtg gcctttaccg gcaatgtgcc caccagcagt atcggcaagg
     6601 acggctttca ggaagcgtac atcgagggca tcacagtgcc catcacaaag cataatttca
     6661 cggtgcgccg ggtagaggat ctggctgaca ccatgcgggc agctttccgc attgcgcaga
     6721 gcggccgcaa gggcccggtg ctggtggata tccccaagga cgtgaccgca gcggtgtgcg
     6781 agttcacccc caagcagccg gagcccatcc gcaccgtaac tacctataat gaggagcagg
     6841 tgcactgggc ggcagacctc atcaacgccg cacagcgtcc gctggtgtac tttggcggcg
     6901 gcgtgcgcag cgcagccagc tgccagccct tgcgggatct gctgcacaag gcagagatcc
     6961 ccgccaccta caccctgatg gccgcaggcg ttgtgcccta tggcgacccg atgaatctgg
     7021 ggatgctggg gatgcacggc tgctacacct ccaaccgggc ggtggcagag tgcgatgtac
     7081 tcatcgcggt gggtacccgc ttttccgacc gcgtggcgct gaaccccaag acctttgcca
     7141 aaaacgccac catcatccag atcgacattg acgccagcga gctgggcaag aacgtggacg
     7201 tggatctttc catcgtgggc gatgcagcct atgtgctgaa cgccatgctg ccccagatca
     7261 agcccgccaa gcacccggaa tggatgaaga tgatccagag ctggcaggcg caggattacc
     7321 accctgtgtc cgaccccacc cggctgatgc cccatcaggt catcggtgag gtgtgcaacc
     7381 agtgcggccc cgacgccgtg tatgttaccg atgtgggtca gcaccagatg tgggcggcgc
     7441 agtacctgcg ccacaccaag agccgcggct ttatcaccag cggcggcctt ggcaccatgg
     7501 gctttggcta cggtgccgcc attggtgccc agatggcact gggacgccag cagcgtgtgg
     7561 tgatgtttac cggcgacgcc tccttccaca tgaacctgaa cgaagcctgc accgccgtca
     7621 gctacgagct gcccatcatc acggtcatct tcaataactc ggtgctgggc atggtacgtc
     7681 agtggcagac cagcttttac ggcaagcgct acagccagac cgacccccac cgcaagaccg
     7741 attttgtcaa gctggcagac ggctttggcc tgaagggcta ccgctgcacc aatctgccgg
     7801 agtttcagga agcgtttgca gatgccctgc agcagaaggg ccccacttgg atcgagtgca
     7861 tcatcgacaa ggacgaaaag gtgctgccca tgatccccgg cggcggcgat atcaacgaca
     7921 tcatcatgga ataaggagga cacagcatca tggaatctga tcagcgcagg gtcatcagcc
     7981 tgctggtgga caaccagagc ggcgttctgg cccgggtgtc cagcctgttc tgccgccgcg
     8041 gcttcaacat cgacagcctt acggtgtccg ccaccaacga cccggcagtc agccgcatca
     8101 cagtgaccat taccagcgat gaaaaggcct tgcagcagct ggtattgcag accgagcggc
     8161 tggaagtcac ccggcaggtg ttcgtgctgg acagcgaaaa agcgctggag cgggagctgc
     8221 tgctgctcaa ggtggaatcg gacgtgcaca accgcacaga gctgcgggag atcgcctgca
     8281 tctacaaggc aaagatcatt gatctttccc cggacagcat ggtgtttgaa ctcatcggcc
     8341 ggccggacaa gctggatgct ttcctgaaaa tgttcgaggg ctacaacatc cttgagcagt
     8401 gccgcaccgg cgttaccgca ctggagcgcg gcgggatgca ccagcatatc cagaagccgc
     8461 cgcaggaggt gcgctccgtc cagctgcccc cgccgggcgc aagacgggca taaatcacat
     8521 tgcttttccg ctcagggtga gcgaaagata gaacagagca tacaagaccg gaagataaac
     8581 caaccagaaa aagtaaaagg agaataacga ttatggctat caagaaatac tacgattccg
     8641 actgcaacct cggcgtgctg gacggcaaga ccgtcgctgt catcggcttc ggcagccagg
     8701 gtcatgcaca ctctgagaat ctggccgaga gcggcgtcaa cgttgtggtc ggcctgcgca
     8761 agggttctgc tcactgggca aaggcttctg agttcgctgc cacccatgac aacttcaagg
     8821 tcatggaggt ggaagaggct gccaaggccg gcgatgttgt catgatgctg gtgcccgatg
     8881 agctgtgcgc cgatatctac aacacccagg ttgctcccta catgaccgag ggcaaggcac
     8941 tggcctttgc acacggcttc aacatccact tcaagaccat caccgcgccc aagaacgtgg
     9001 acgtcatcat gatcgctccc aagggccccg gccacatcgt gcgccgcctg tacaccgagg
     9061 gcgagggctg cccctctctg atctgcgtgg agcaggacta caccggtaag gccaaggata
     9121 tcgcactggc ttatgcttcc ggcatcggcg caggccgtgc aggcattctg cagaccacct
     9181 tcaaggagga gaccgagacc gatctgttcg gcgagcaggc cgtgctgtgc ggcggtgttt
     9241 ccgagctgat ccacgccggc ttcgatacgc tggtggaggc cggctacgag cccgagatgg
     9301 cctactttga gacctgccac gagatgaagc tgatcgttga cctgatcaac gagggcggct
     9361 tct
//
