LOCUS       c00239_gnlPro..         9487 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OPFHCHNF_239.
ACCESSION   c00239_gnlPro..
VERSION     c00239_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:21:51
            Original ID  :: gnl|Prokka|OPFHCHNF_239
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9487
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9487
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:6577]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..6577
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..9487
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9487
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..751)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_1"
                     /sec_met_domain="IlvN (E-value: 2e-75, bitscore: 241.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 5.9e-34, bitscore: 106.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHDNFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVSELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGF"
     CDS             complement(851..1414)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_2"
                     /sec_met_domain="ALS_ss_C (E-value: 1.2e-28, bitscore:
                     88.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDSEKALERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHIQKPPQEVRSVQLPPPGARRA"
     CDS             complement(1430..3094)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-51, bitscore:
                     163.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLNGSQIFVEVLCEQGVDTLFGYPGGAVLNLYDELYKNADRITH
                     VLTAHEQGAAHAADGYARATGRTGVVLATSGPGATNLVTGIATAYMDSVPMVAFTGNVP
                     TSSIGKDGFQEAYIEGITVPITKHNFTVRRVEDLADTMRAAFRIAQSGRKGPVLVDIPK
                     DVTAAVCEFTPKQPEPIRTVTTYNEEQVHWAADLINAAQRPLVYFGGGVRSAASCQPLR
                     DLLHKAEIPATYTLMAAGVVPYGDPMNLGMLGMHGCYTSNRAVAECDVLIAVGTRFSDR
                     VALNPKTFAKNATIIQIDIDASELGKNVDVDLSIVGDAAYVLNAMLPQIKPAKHPDWMT
                     MIQSWQAQDYHPVSDPTRLMPHQVIGEVCNQCGPDAVYVTDVGQHQMWAAQYLRHTKSR
                     GFITSGGLGTMGFGYGAAIGAQMALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIIT
                     VIFNNSVLGMVRQWQTSFYGKRYSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFA
                     DALQQKGPTWIECIIDKDEKVLPMIPGGGDINDIIME"
     CDS             3621..4838
                     /locus_tag="ctg239_4"
                     /transl_table=11
                     /translation="MKLREWNAHLHGLVVFRALLNDPVVAKLLDLTDRMEAGSSSYGPV
                     CDAVAAFEAALFEYTTNWGSYLSSAVLEAETICVRQAAAGQLDALLQSALDSELQFLQQ
                     LCGLTLDELFQTAYSEQAQRPELAFLPRWQTCELDLAAAYTQRMSEVGKKGYGMFAKHH
                     VFTVENGQLVPVKYPDPQRLSELPGYEKEREKVIANTKALLAGMPANNVLLYGDAGTGK
                     SSAVKAIANEFAPEGLRLVEVKKNQLYQIPDLMDKLAANPLKFILFIDDLSFTANDDNF
                     AALKAILEGSVGGRAQNIAVYATSNRRHLIKETLSDRTGDDIHEADTRQELMSLSARFG
                     LTVTFQRPEKARFETILEELAKQHNIQMPTEQLLLKAEAFALRAGGRSPRVAKQFIEQC
                     EAGVQK"
     CDS             complement(4926..5300)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ribonuc_L-PSP"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1038:Endoribonuclease L-PSP (Score: 149.8; E-value:
                     1.2e-46)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg239_5"
                     /sec_met_domain="Ribonuc_L-PSP (E-value: 1.7e-47, bitscore:
                     149.8, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVSTANAPAAIGPYSQALDLGNMVFVSGQLPVDPATGTMADTV
                     EQQAAQSLANLKAILAEAGLSMNNVVKTVIFLADINDFAAVNAEYAKAFAEPFPARSCV
                     QVAAIPKGAKLEIECIAVRD"
     CDS             complement(5372..6577)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_6"
                     /sec_met_domain="PALP (E-value: 2.6e-94, bitscore: 305.1,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLDKIYHAAFVLKDVARKTDLIEAPKLSKDCQLYLKTENLQAT
                     GSFKVRGAYYKISQLSEEESAKGVIACSAGNHAQGVALAATRRGIRSIVCMPDGAPLMK
                     VENTKNLGAEVCLVPGTYDEAHDKAVQLQKEYDMTFIHPYDDEQVIAGQGTIGLEILDQ
                     LPDVDAVVVPVGGGGLISGIAFAIKTLRPEVKVYGVQAEGAPSMYRSLHEHKYQTLKSA
                     STFADGIQVKTPGELTYQLCEQYVDDIVTVTEDETAAAILSLMENQKLVAEGAGAVPVA
                     AVLFHKLPVEGKKVACVISGGNIDVNILNRVITRGLVMSGRKANLTIALEDKPGQLKKV
                     AEVVSRCGSNVVSVQHDGSDPNMPISSCFLKLTLETRDAAQIEQIRTELTKAGFQLVSE
                     RV"
     CDS             complement(6720..7628)
                     /locus_tag="ctg239_7"
                     /transl_table=11
                     /translation="MKNFAKRISALVLAVVVSAAVLCPAAFAAQLPSLPKDQCVVDDAG
                     VLSSSTVQTITELNAQLESSCSGAQIGVLTVEYTGNDSTEEYATQAFNAWGIGSSSKNN
                     GVLILLVMESAQYADGDYYLTYGDGFRNTTLAKQSSAIAQTMEDQFAAKDYDGAVTTCA
                     RNVANTIADIYGVSLSGGTGNGSTVQPGYQGGQSSGGSTLTDILTLVVSVVLLIVIIRS
                     MAYVFASPCGWLWCFGGPRPPRGRRRGPHNPPPPPGGFYGGFGGMGGGSFGGGAGRGGF
                     GGGFGGMGGGSSHGGGGGRGR"
     CDS             complement(7625..8383)
                     /locus_tag="ctg239_8"
                     /transl_table=11
                     /translation="MANADFSQNKQTAPGGFDAGSYREKAKPEQAVRLTPRQQKLAALE
                     AKLPAALSTRAAALALSVVVMLAAFFGFGSAKLRGKYNTARQWFTAGVAADNGYNLSEE
                     LTTRENTAANILTTASNTLGADSAEVLSAQTALNDFSACLQAVQNGGKSQSLTSLPYYQ
                     GSTMHALYQADQALGAAIDQLYAKLQEQAADPMKMGAVQGQYGQFNSAATIIGTLQYNT
                     AVYEYQNEVGGFPASVLGALSGVKEVEPFA"
     CDS             complement(8385..9485)
                     /locus_tag="ctg239_9"
                     /transl_table=11
                     /translation="LTLDPTPAAVPQEEKPAAAPAPEAQVNLTPEEQAMVDQFAQKIDI
                     TNSQQVLQYGSACQKKIGDFSEAALSKVSTKDLGEVGDMITDLIGELKSFDANEEQQKG
                     IMGFFKKKTSQLEALKTKYDKTETNVEKIQSMLEAHQVQLLKDIAMLDKMYELNMAYFK
                     ELSMYILAGKKKLADVRANELQQAMDKAKVSGLPEDAQAARDLADQCERFEKKLYDLEL
                     TRNISLQMGPQIRLLQNNNTMMAEKIQSTIVNTIPLWKNQMVLALGLAHSQQAMQAERA
                     VTNMTNDLLKKNAEALKLGTIETAKESQRGIVDIETLQQTNKSLIETLDELNKIQSEGR
                     AKRVAAEQELTRIEDELKTKMMEIRS"
ORIGIN
        1 agaagccgcc ctcgttgatc aggtcaacga tcagcttcat ctcgtggcag gtctcaaagt
       61 aggccatctc gggctcgtag ccggcctcca ccagcgtatc gaaaccggcg tggatcagct
      121 cggaaacacc gccgcacagc acggcctgct cgccgaacag atcggtctcg gtctcctcct
      181 tgaaggtggt ctgcaggatg cctgcacggc ctgcgccgat gccggaagca taagccagtg
      241 cgatatcctt ggccttaccg gtgtagtcct gctccacgca gatcagagag gggcagccct
      301 cgccctcggt gtacaggcgg cgcacgatgt ggccggggcc cttgggagcg atcatgatga
      361 cgtccacgtt cttgggagcg gtgatggtct tgaagtggat gttgaagccg tgtgcaaagg
      421 ccagtgcctt gccctcggtc atgtagggag caacctgggt gttgtagata tcggcgcaca
      481 gctcatcggg caccagcatc atgacaacat cgccggcctt ggcagcctct tccacctcca
      541 tgaccttgaa gttgtcatgg gtggcagcga actcagaagc ctttgcccag tgggcagagc
      601 ccttgcgcag gccgaccaca acgttgacgc cgctctcggc cagattctca gagtgtgcat
      661 gaccctggct gccgaaaccg atgacagcga cggtcttgcc gtccagcacg ccgaggttgc
      721 agtcggaatc gtagtatttc ttgatagcca taatcgttag tctcctttta ctttttctga
      781 ttggtttatc ttccggtctt gtatgctctg ttctatcttt cgctcaccct gagcggaaaa
      841 gcaatgtgat ttatgcccgt cttgcgcccg gcgggggcag ctggacggag cgcacctcct
      901 gcggcggctt ctggatatgc tggtgcatcc cgccgcgctc cagtgcggta acgccggtgc
      961 ggcactgctc aaggatgttg tagccctcga acattttcag gaaagcgtcc agcttgtccg
     1021 gccggccgat gagttcaaac accatgctgt ccggggaaag atcaatgatc tttgccttgt
     1081 agatgcaggc gatctcccgc agctctgtgc ggttgtgcac gtccgattcc accttgagca
     1141 gcagcagctc ccgctccagc gctttttcgc tgtccagcac gaacacctgc cgggtgactt
     1201 ccagccgctc ggtctgcaat accagctgct gcaaggcctt ttcatcgctg gtaatggtca
     1261 ctgtgatgcg gctgactgcc gggtcgttgg tggcggacac cgtaaggctg tcgatattga
     1321 agccgcggcg gcagaacagg ctggacaccc gggccagaac gccgctctgg ttgtccacca
     1381 gcaggctgat gaccctgcgc tgatcagatt ccatgatgct gtgtcctcct tattccatga
     1441 tgatgtcgtt gatatcgccg ccgccgggga tcatgggcag caccttttcg tccttgtcga
     1501 tgatgcactc gatccaggtg gggcctttct gctgcagggc atctgcaaag gcttcctgaa
     1561 actccggcag gttggtgcag cggtagccct tcaggccaaa gccgtctgcc agcttgacaa
     1621 aatcggtctt gcggtggggg tcggtctggc tgtaacgctt gccgtaaaag ctggtctgcc
     1681 actggcgcac catgcccagc accgagttat tgaagatgac cgtgatgatg ggcagctcgt
     1741 agctgacagc ggtgcaggct tcgttcaggt tcatgtggaa ggaggcgtca ccagtaaaca
     1801 tcaccacacg ctgctggcgt cccagtgcca tctgggcacc aatggcagcg ccgtagccaa
     1861 agcccatggt gccaaggccg ccgctggtga taaagccacg gctcttggtg tggcgcaggt
     1921 actgcgccgc ccacatctgg tgctgaccca cgtcggtaac atacacggcg tcggggccgc
     1981 actggttgca cacctcgccg atgacctgat ggggcatcag ccgggtgggg tcggacacag
     2041 ggtggtaatc ctgtgcctgc cagctctgga tcatcgtcat ccagtccggg tgcttggcgg
     2101 gcttgatctg gggcagcatg gcgttcagca cataggctgc atcgcccacg atggaaagat
     2161 ccacgtccac gttcttgccc agctcgctgg cgtcaatgtc gatctggatg atggtggcgt
     2221 tcttggcaaa ggtcttgggg ttcagcgcca cacggtcgga aaagcgggtg cccaccgcga
     2281 tgagcacatc gcactccgcc actgcccggt tggaggtgta gcagccgtgc atccccagca
     2341 tccccagatt catcgggtcg ccgtagggca caacgcctgc cgccatcagg gtgtaggtag
     2401 cagggatctc cgccttgtgc agcagatccc gcagcggctg gcagctggct gcgctgcgca
     2461 cgccgccgcc aaagtacacc agcggacgct gtgcggcgtt gatgaggtct gccgcccagt
     2521 gcacctgctc ctcattatag gtagttacgg tgcggatggg ctccggctgc ttgggggtga
     2581 actcgcacac cgctgcggtc acgtccttgg ggatgtccac cagcaccggg cccttgcggc
     2641 cgctctgcgc aatgcggaag gccgcccgca tggtgtcagc caagtcctct acccggcgca
     2701 ccgtgaaatt atgctttgtg atgggcacgg tgatgccctc gatgtacgct tcctgaaagc
     2761 cgtccttgcc gatactgctg gtgggcacgt tgccggtaaa ggccaccatg ggcaccgagt
     2821 ccatataggc ggtggcaatg ccggtgacca gattggtggc acccgggccg ctggtggcca
     2881 gcaccacgcc ggtgcggccg gtggcgcggg cgtagccgtc cgctgcatgg gctgcgccct
     2941 gctcgtgggc ggtaagcaca tgggtgatgc ggtcggcatt cttatacagc tcgtcgtaaa
     3001 ggttcagcac agcgccgccg gggtagccaa aaagagtgtc cactccctgc tcgcacagga
     3061 cctctacaaa gatctgagaa ccattcaact gcatggtgtt gctcctattc ctgttccact
     3121 tcttatccat tccctcaggg agagcttttg aaaaagaaaa agcccttgtc ccctgctttc
     3181 ttcaagagac aaagaccttg taacatcaag ctctctgcgg taccactctc gttggcgtgc
     3241 tgtgcacacc ctctcacggg cttccaacaa agccctgcac ggtaacggct gcaaccggcg
     3301 ctgcttacaa gggttttgca cccgttgggc aggctgctcc gggatgattt tccgcacgaa
     3361 acgctgactg ccttgcacca gacggcagct ctctgaacag tggggatcgt gtggtacttt
     3421 ttcccatctg cgcatttgtt gatgtaaatt atactataaa ccgggctttt gtcaatcgac
     3481 aatttgtaac ctgaatcacc cgaaagatga agcattttta acaccccttg catccaagcc
     3541 tgaaccgctg tatacttttg atatccgcgt acctgcgttt tgtagggtat gtgccaatgg
     3601 agaggaaaag ggatcgacct atgaaattaa gagaatggaa tgcccatctg catgggcttg
     3661 ttgtgttccg cgccctgctg aacgaccctg ttgtggcaaa gcttttagac ctgaccgacc
     3721 gcatggaggc cggcagctcc tcctacggcc cggtgtgcga tgccgtagcc gcctttgagg
     3781 ccgctttgtt cgagtacacc accaactggg gcagctacct gagcagcgcc gtgctggagg
     3841 ccgagaccat ctgcgtgcgg caggccgctg ccgggcagct ggacgcgctg ctgcaaagcg
     3901 ccttggacag cgagctgcag tttttgcagc agctgtgcgg gctgacgctg gacgaactgt
     3961 tccagaccgc ctactcggag caggcgcagc ggccggagtt ggcgttcctg ccccggtggc
     4021 agacctgtga gcttgacctt gccgccgcct acacccagcg catgagcgag gtgggcaaaa
     4081 agggctacgg tatgtttgca aagcaccatg tattcacggt ggagaacggc cagcttgtgc
     4141 cggtaaaata ccccgacccg cagcgccttt ccgagctgcc aggctacgag aaggagcggg
     4201 aaaaggtgat tgccaacaca aaggcactgc tagccgggat gcccgccaac aatgtgctgc
     4261 tgtacggtga cgccggtacc ggcaaatcca gcgcggtaaa ggccattgcc aacgagtttg
     4321 cgcccgaggg gctgcggctg gtagaggtga aaaagaacca gctgtaccag atccccgacc
     4381 tgatggacaa gctggcggca aacccgctca agttcatttt gttcatcgac gatctgagct
     4441 ttaccgccaa cgacgacaac tttgccgcct tgaaggccat cctggagggc agcgtaggcg
     4501 gccgcgccca gaacattgcg gtgtacgcca cttccaaccg ccgccatctc atcaaggaga
     4561 ctctctcgga ccgcaccggc gacgacatcc acgaagccga cacccggcag gagctgatga
     4621 gcctttctgc ccggttcggc ctgacggtca ccttccagcg gccggaaaag gcacggttcg
     4681 agaccattct ggaggagctg gcaaagcagc acaacatcca gatgcccacc gagcagctgc
     4741 tgctcaaggc cgaggccttc gctctgcgtg ccggcggccg cagcccccgg gtggccaagc
     4801 aattcatcga gcaatgcgag gccggtgtgc agaagtaaac gcaccagttt taaatgttat
     4861 caaaaagcgg gacaccaaag catccgcaga tgctccggtg tcccgctttt cttgtcttta
     4921 ttcgctcagt cccgcacggc gatgcactcg atctccagct ttgcgccctt ggggatggct
     4981 gccacctgca cacagctgcg ggcggggaac ggctcggcaa aggccttggc gtactctgcg
     5041 ttcactgcgg caaaatcgtt gatgtcggcc agaaagatca ccgtcttgac cacgttgttc
     5101 atggaaagcc ccgcctcggc cagaatcgcc ttcaggttgg caaggctctg ggcggcctgc
     5161 tgctccacgg tatcagccat ggtgccggtg gctgggtcta ccgggagctg cccggaaaca
     5221 aacaccatat tgcccagatc cagtgcctga ctgtaagggc cgatggcggc aggtgcgttg
     5281 gcggtagata cgactttcat agtatatttt ctcctttata ttactttaag tttgatgcaa
     5341 attctctttt cactcaggca aacgatgaag tttacacccg ctcgctgacc agctggaagc
     5401 cggccttggt cagctcggtg cggatctgct cgatctgggc ggcatcgcgg gtctccagcg
     5461 tcagcttgag gaagcagctg gagatgggca tattggggtc ggagccgtca tgctgcaccg
     5521 acaccacatt gctaccgcag cgggatacca cctcggccac ctttttcagc tggccgggct
     5581 tgtcctccag cgcgatggtc aggtttgcct tgcggccgct catcacaaga ccgcgggtga
     5641 tgacgcggtt caggatgttt acatcaatgt tgccgccgga gatgacgcag gccacctttt
     5701 tgccctctac cggcagcttg tggaacagca ctgccgccac cggcacagcg cctgcaccct
     5761 cagccaccag cttctggttc tccatcaggg agagaatggc cgccgccgtc tcgtcctcgg
     5821 tcacggtaac gatatcgtcc acatactgct cgcatagctg ataggtcagc tcgcccgggg
     5881 tcttgacctg aataccgtcc gcaaaggtgg aagcagattt cagggtctgg tacttgtgct
     5941 cgtgcaggct gcggtacata ctgggggcac cctcggcctg tacgccgtac accttgacct
     6001 ccgggcgcag ggtcttgatg gcaaaggcaa taccggaaat cagtccgccg ccgcccaccg
     6061 gcaccaccac agcatccaca tccggcagct ggtcaaggat ctccaagccg atggtaccct
     6121 gcccggcgat gacctgctcg tcatcgtagg ggtggataaa ggtcatgtcg tactcctttt
     6181 gcagctgcac ggccttgtcg tgggcttcgt cgtaggtgcc gggcacaagg cagacctccg
     6241 cgcccagatt tttggtgttt tccaccttca tcaggggtgc gccgtccggc atacagacga
     6301 tgctgcggat gccgcgccgg gtagccgcca gcgccacacc ctgcgcatgg ttgcccgcag
     6361 agcaggcaat gacgcccttg gcgctctcct cctcagaaag ctggctgatt ttatagtaag
     6421 cgccccgcac cttaaagctg ccggtggcct gcaggttctc ggtcttgagg tacagctggc
     6481 agtccttgga cagcttgggg gcttcgatga ggtcggtctt gcgcgccacg tccttcagca
     6541 caaaggcggc gtggtagatc ttatccagag tcagcatgac agatacttcc tttatttttc
     6601 gtgatgtcat ccagtataag ttacaaaaat tgttttgtca aatgaattcc attcacgata
     6661 aaaggcgtaa aaaagagaaa ggcagtggta aagccaccgc ctttctcttt ttattctcat
     6721 taccgcccac ggccaccgcc gccgccatgg ctggaaccac cgcccatgcc accgaagccg
     6781 ccgccgaaac cgccgcggcc ggcaccgccc ccgaaggagc cgccgcccat gccgccaaag
     6841 ccgccgtaga agccgcccgg cgggggcggc gggttatgcg ggccgcgccg ccgtccacgg
     6901 ggaggccggg gcccgccgaa gcaccacagc cagccgcagg ggctggcaaa aacataggcc
     6961 atcgaccgga tgatgacgat gagcagcaca acgctgacca caagggtcag gatgtcggtc
     7021 agggtgctgc cgccgctgct ctgcccgccc tgatagccgg gctgcacggt gctgccgtta
     7081 ccggtgccgc cggaaaggct gacgccgtag atatccgcga tggtgtttgc cacgttgcgg
     7141 gcacaggtgg tcactgcgcc gtcataatcc tttgcggcga actggtcctc catggtctgg
     7201 gcgatggcgc tggactgctt tgccagcgtg gtgttgcgga aaccgtcgcc gtaggtcagg
     7261 tagtagtcgc cgtccgcgta ctgtgccgac tccatcacaa gcaggatcag aacgccgttg
     7321 ttcttggagg aggaaccgat gccccacgcg ttgaaggcct gtgtggcgta ttcctctgtg
     7381 gaatcattgc ctgtatattc tacagtcagt acaccgatct gcgcgccgct gcagctggat
     7441 tccagctggg cgttcagttc ggtgatggtc tgcacggtgc tgctgctcag cacaccggca
     7501 tcgtccacca cgcactgatc cttgggcagg ctgggcagct gggcggcaaa agccgccggg
     7561 cacagcactg ccgcgctgac caccacggcc agcaccagtg cgctgatgcg ttttgcaaag
     7621 tttttcatgc gaagggctca acctccttca cgccggacaa agcgcccagt acactggccg
     7681 ggaagccgcc gacttcattc tgatattcat acaccgccgt attgtactgc aaagtaccaa
     7741 tgatggtggc tgcgctgttg aactggccgt actgcccctg caccgcaccc atcttcatgg
     7801 ggtctgcggc ctgctcctgc aattttgcat acagctggtc gatggcagcg cccagtgcct
     7861 gatcggcctg atacagcgcg tgcatcgtgc tgccctgata atagggcagc gaggtcagcg
     7921 actggctttt gccgccgttc tgcaccgcct gcaggcaagc ggagaaatcg ttcagagccg
     7981 tctgtgcaga cagcacctcg gcgctgtctg caccaagagt attggaggcg gtggtcagga
     8041 tgttcgccgc cgtattctcc cgggtggtca gctcctcgct caggttataa ccgttgtcgg
     8101 cggcgacccc tgcggtgaac cactggcggg cggtgttgta tttgccccgc agcttggcgc
     8161 tgccaaagcc gaaaaaggcg gccagcatca ccaccacact caaagccagc gccgctgccc
     8221 gggtggaaag cgcagcgggc agctttgctt ccagtgcggc cagcttctgc tggcggggcg
     8281 tcagccttac ggcctgctcc ggctttgctt tttcgcgata gctgcccgcg tcaaaaccgc
     8341 cgggagcggt ttgtttgttc tgagaaaaat cagcgtttgc catttcagct ccggatctcc
     8401 atcattttgg ttttcagctc gtcctcgatg cgggtcagct cctgctcggc ggcaacgcgc
     8461 tttgcacggc cctcgctctg gatcttgttc agctcgtcca gcgtctcgat caggctcttg
     8521 ttggtctgct gcaaggtctc gatatccacg atgccgcgct ggctctcctt ggcggtctcg
     8581 atggtgccca gcttcagcgc ctcggcgttc ttcttcagca ggtcgttggt catgttggtc
     8641 acagcgcgct ctgcctgcat ggcctgctgg ctgtgtgcca gacccagtgc cagcaccatc
     8701 tggttcttcc acagagggat ggtgttcacg atggtggact ggatcttttc tgccatcatg
     8761 gtgttgttgt tttgcagcag acggatctgg ggacccatct gcaaactgat gttgcgggtc
     8821 agctccagat catacagctt tttctcaaag cgctcgcact ggtcggcaag gtcgcgggcg
     8881 gcctgtgcgt cctccggcag accggagacc ttggccttat ccatagcctg ctgcaattcg
     8941 ttggcacgca catcggccag ctttttcttg ccggcaagga tatacatgct cagctccttg
     9001 aagtaggcca tgttcagctc gtacattttg tccagcatgg caatgtcctt gagcagctgc
     9061 acctgatggg cttccagcat ggactggatc ttttccacgt tggtctcggt cttgtcgtac
     9121 ttggtcttga gggcctccag ctggctggtt ttctttttga agaagcccat aatgcccttc
     9181 tgctgctcct cgttggcgtc aaagctcttc agctcgccaa tgaggtcggt gatcatatcg
     9241 cccacctcgc ccagatcctt ggtggacacc ttggagaggg ctgcttcgga gaaatcgccg
     9301 atcttcttct ggcaggcaga gccgtattgc agcacctgct ggctgttggt gatatcgatc
     9361 ttctgggcaa actgatccac catggcctgc tcctcggggg tcaggttcac ctgtgcttcc
     9421 ggggcagggg cagcggcggg cttttcctcc tgcggcacag ctgcgggggt ggggtccagc
     9481 gtcaggg
//
