GCA_014870065.1 - 3 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaENJKBHIJ_8 (original name was: gnl|Prokka|ENJKBHIJ_8)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	RRE-containing	1	13,335

gnlProkkaENJKBHIJ_11 (original name was: gnl|Prokka|ENJKBHIJ_11)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	ranthipeptide	4,865	26,238

gnlProkkaENJKBHIJ_50 (original name was: gnl|Prokka|ENJKBHIJ_50)

Region	Type	From	To	Most similar known cluster		Similarity
Region 50.1	HR-T2PKS,NRPS	1	75,373	leucomycin	Polyketide	3%

Region	Type	From	To	Most similar known cluster	Similarity
Region 8.1	RRE-containing	1	13,335
Region 11.1	ranthipeptide	4,865	26,238
Region 50.1	HR-T2PKS,NRPS	1	75,373	leucomycin	Polyketide	3%

No secondary metabolite regions were found in these records:: gnlProkkaENJKBHIJ_1 (original name was: gnl|Prokka|ENJKBHIJ_1); gnlProkkaENJKBHIJ_2 (original name was: gnl|Prokka|ENJKBHIJ_2); gnlProkkaENJKBHIJ_3 (original name was: gnl|Prokka|ENJKBHIJ_3); gnlProkkaENJKBHIJ_4 (original name was: gnl|Prokka|ENJKBHIJ_4); gnlProkkaENJKBHIJ_5 (original name was: gnl|Prokka|ENJKBHIJ_5); gnlProkkaENJKBHIJ_6 (original name was: gnl|Prokka|ENJKBHIJ_6); gnlProkkaENJKBHIJ_7 (original name was: gnl|Prokka|ENJKBHIJ_7); gnlProkkaENJKBHIJ_9 (original name was: gnl|Prokka|ENJKBHIJ_9); gnlProkkaENJKBHIJ_10 (original name was: gnl|Prokka|ENJKBHIJ_10); gnlProkkaENJKBHIJ_12 (original name was: gnl|Prokka|ENJKBHIJ_12); gnlProkkaENJKBHIJ_13 (original name was: gnl|Prokka|ENJKBHIJ_13); gnlProkkaENJKBHIJ_14 (original name was: gnl|Prokka|ENJKBHIJ_14); gnlProkkaENJKBHIJ_15 (original name was: gnl|Prokka|ENJKBHIJ_15); gnlProkkaENJKBHIJ_16 (original name was: gnl|Prokka|ENJKBHIJ_16); gnlProkkaENJKBHIJ_17 (original name was: gnl|Prokka|ENJKBHIJ_17); gnlProkkaENJKBHIJ_18 (original name was: gnl|Prokka|ENJKBHIJ_18); gnlProkkaENJKBHIJ_19 (original name was: gnl|Prokka|ENJKBHIJ_19); gnlProkkaENJKBHIJ_20 (original name was: gnl|Prokka|ENJKBHIJ_20); gnlProkkaENJKBHIJ_21 (original name was: gnl|Prokka|ENJKBHIJ_21); gnlProkkaENJKBHIJ_22 (original name was: gnl|Prokka|ENJKBHIJ_22); gnlProkkaENJKBHIJ_23 (original name was: gnl|Prokka|ENJKBHIJ_23); gnlProkkaENJKBHIJ_24 (original name was: gnl|Prokka|ENJKBHIJ_24); gnlProkkaENJKBHIJ_25 (original name was: gnl|Prokka|ENJKBHIJ_25); gnlProkkaENJKBHIJ_26 (original name was: gnl|Prokka|ENJKBHIJ_26); gnlProkkaENJKBHIJ_27 (original name was: gnl|Prokka|ENJKBHIJ_27); gnlProkkaENJKBHIJ_28 (original name was: gnl|Prokka|ENJKBHIJ_28); gnlProkkaENJKBHIJ_29 (original name was: gnl|Prokka|ENJKBHIJ_29); gnlProkkaENJKBHIJ_30 (original name was: gnl|Prokka|ENJKBHIJ_30); gnlProkkaENJKBHIJ_31 (original name was: gnl|Prokka|ENJKBHIJ_31); gnlProkkaENJKBHIJ_32 (original name was: gnl|Prokka|ENJKBHIJ_32); gnlProkkaENJKBHIJ_33 (original name was: gnl|Prokka|ENJKBHIJ_33); gnlProkkaENJKBHIJ_34 (original name was: gnl|Prokka|ENJKBHIJ_34); gnlProkkaENJKBHIJ_35 (original name was: gnl|Prokka|ENJKBHIJ_35); gnlProkkaENJKBHIJ_36 (original name was: gnl|Prokka|ENJKBHIJ_36); gnlProkkaENJKBHIJ_37 (original name was: gnl|Prokka|ENJKBHIJ_37); gnlProkkaENJKBHIJ_38 (original name was: gnl|Prokka|ENJKBHIJ_38); gnlProkkaENJKBHIJ_39 (original name was: gnl|Prokka|ENJKBHIJ_39); gnlProkkaENJKBHIJ_40 (original name was: gnl|Prokka|ENJKBHIJ_40); gnlProkkaENJKBHIJ_41 (original name was: gnl|Prokka|ENJKBHIJ_41); gnlProkkaENJKBHIJ_42 (original name was: gnl|Prokka|ENJKBHIJ_42); gnlProkkaENJKBHIJ_43 (original name was: gnl|Prokka|ENJKBHIJ_43); gnlProkkaENJKBHIJ_44 (original name was: gnl|Prokka|ENJKBHIJ_44); gnlProkkaENJKBHIJ_45 (original name was: gnl|Prokka|ENJKBHIJ_45); gnlProkkaENJKBHIJ_46 (original name was: gnl|Prokka|ENJKBHIJ_46); gnlProkkaENJKBHIJ_47 (original name was: gnl|Prokka|ENJKBHIJ_47); gnlProkkaENJKBHIJ_48 (original name was: gnl|Prokka|ENJKBHIJ_48); gnlProkkaENJKBHIJ_49 (original name was: gnl|Prokka|ENJKBHIJ_49); gnlProkkaENJKBHIJ_51 (original name was: gnl|Prokka|ENJKBHIJ_51); gnlProkkaENJKBHIJ_52 (original name was: gnl|Prokka|ENJKBHIJ_52)

Compact view

gnlProkkaENJKBHIJ_8 - Region 1 - RRE-containing

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Location: 1 - 13,335 nt. (total: 13,335 nt) Show pHMM detection rules used

Region on contig edge.

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaENJKBHIJ_11 - Region 1 - ranthipeptide

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Location: 4,865 - 26,238 nt. (total: 21,374 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaENJKBHIJ_50 - Region 1 - HR-T2PKS,NRPS

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Location: 1 - 75,373 nt. (total: 75,373 nt) Show pHMM detection rules used

Region on contig edge.

HR-T2PKS: (hr-t2pks-ksa and (t2fas or APE_KS2 or ketoacyl-synt))
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 75373:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 28041 - 75373:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg50_48

Search NORINE for peptide: strict or relaxed

AMP-binding (457..845): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DASFLGGVYK
Nearest Stachelhaus code(s):: Ile DALFMGGVYK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (1479..1869): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMKNLGTVSK
Nearest Stachelhaus code(s):: Asp DMKDLGMVDK (53% 8Å match)
Stachelhaus code match:: 70% (weak)