LOCUS       gnlProkkaENJKBHIJ_8    13335 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ENJKBHIJ_8.
ACCESSION   gnlProkkaENJKBHIJ_8
VERSION     gnlProkkaENJKBHIJ_8
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:44:49
            Original ID  :: gnl|Prokka|ENJKBHIJ_8
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13335
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..387
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="MSKVKSHTNELNWIGNGMYDGSIGQFFELYFNFYMQILFIAFAAG
                     IYFLFINRKTNIETVLLPLVILGAFGYHLLFEGKSQYVLTYIILMIPTASFAFECILNG
                     KYTKIKEFVGKLKEIPDGKESEKA"
     protocluster    1..13335
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3071:3335]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3072..3335
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13335
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13335
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(409..1275)
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MVRIITDSAADFEHSESEKFGISTVPLAVYIDGKEYKDDFLHSKE
                     RFYRLAKLSKTLPKTSQPSPYVYECALKKARDNGESVVVITVSSALSGSYQSAVLARDL
                     LGYEGCYVIDSKSASAGQKLLVNEALRLRDNGFTAKEIAEHLLRFRSRIMVYACIDDMK
                     YLYGGGRHTNAAALLGSTGRIKPVISITGSGSVAFEAKTIGMRHGMNHMLMSLKKLGID
                     QNYPLYIMHTNAKNQALYLSKLIISKGIPFVEGSIVSVGSVVGSHIGEGSTGIAFVKKE
                     QRKSGHD"
     CDS             complement(1512..2600)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.5e-38, bitscore:
                     123.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKHLNDNEKIEFKYLLELVSSSVNGTAPPIPYEGIKWQSIKMLA
                     NYCSVESFVANAVLSLDKKYVSPEVYEKFKQDLSVEMLIDGNLSYETEKILKAFDENKI
                     KNIPLKGYFMKKEYPRSDFRSVSDVDILFDRKQADLVKKVFSKLGYTFLNEDDNQYHFE
                     KKPMMNIEMHATLVHENEESYPLLVNQLDRSTRRDGYSYSYEMSHEDFYIYMLVHNSNH
                     FRIGGMGIRMVLDSYVFLKNHQSELDYDYLNVMLEKIGIAKYEKRVREIAFNWFSKPQA
                     ELKFDDIEEYILLSGTLGRVDVGTMINSHKTITENNKSKFSYLVSSIFPPKSEMQYKYP
                     YVKKHRSFYRFHGVICGEKGFL"
     CDS             complement(2597..3085)
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MSLNKEVGLDDVMQIIAEKLEAGGSVTFNPKGTSMLPMLRDGDDT
                     VVLSKPKGRLHLFDLPLYRRKDGSYVLHRVVNFGSDGSYTMCGDNQFAVEKGITDDDVI
                     GVVTAFYRKGKPYTVDSMKYRAYLEFMFYSKPLRKVIASTVSRSKNAFSKLKTKKGEK"
     CDS             complement(3072..3335)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_5"
                     /sec_met_domain="PF05402 (E-value: 3.4e-17, bitscore: 54.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.2e-13,
                     bitscore: 42.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKEDFVLRKVADSYVVVPVNKLTLDFNGIINLNETGAFLFEKL
                     QNDCEKADLLKAMLDEYEVSEEKASADIDTFIQKLREADVLE"
     CDS             complement(3490..5118)
                     /gene_functions="other (smcogs) SMCOG1299:chaperonin GroEL
                     (Score: 814.4; E-value: 5.8e-247)"
                     /gene_kind="other"
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MAKQIAYGEDARKALMKGIDQLADTVKITLGPKGRNVVLDKKFGA
                     PLITNDGVTIAKEIELEDPFENMGAQLVKEVSIKTNDIAGDGTTTATLLAQALIREGMK
                     NVTAGANPMVLKKGIADAVNVAVEAVKKNSKQVSGTDDIARVATVSSQDEFIGKLIAEA
                     MEKVTTDGVITVEESKTAETYSEVVEGMMFDRGYIAPYMVTDTDKMVAELDNPLILITD
                     KKISTTQEILPLLEQIVQMGKKLLIIAEDVEGEALTTLVLNKLRGTFTCVAVKAPGFGD
                     RRKEMLQDIATLTGGTVITSDLGLELKDTTVDQLGTARQVKIEKENTIIVDGSGDKEAI
                     KGRVAQIRQQIETTTSDFDREKLQERLAKLAGGVAVIKVGAATEVEMKEKKLRIEDALA
                     ATKAAVEEGIVAGGGIACMNAIPAVAEFVDTLEGDAKTGAKIVLKALEEPLRQIVANAG
                     LEGSVICDNVKKANKVGYGFNALTEEYTDMVSAGIVDPTKVTRSALQNASSVAAMVLTT
                     ESLVTDIKEPAAPAAPAAPDMGGMY"
     CDS             complement(5147..5431)
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MTIKPLLDRVVLKVEEAEEKTKSGIILSSAAQEKPQFASVVAVGP
                     GGVVDGKEVKMYVSVGDKVIASKYAGTQVKIDGEEYTIVNQSDILATLE"
     CDS             complement(5695..7332)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 81.3;
                     E-value: 1.4e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_8"
                     /sec_met_domain="Pkinase (E-value: 1.2e-13, bitscore: 42.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLCMGCMQEIGDNKICPSCGFDTTEKQQAPFLPYGTILQNRYIV
                     GAGIDTNGESTRYISHDKQTGDIVIICEFLPIGLFSREEGTTEVRINYENRLVYNKLKD
                     DFLNYYRILSELRELSALMNVHNIFEENNTVYVVEENEDLIPFEEYVERSNGHLEWDIA
                     RPLFMPVISALEALHKRGVGHYAIAPKNMYITASGKIKISGFASENERKRGTPLKSQLF
                     SGAAAPEQYDDNFPLDDITDIYGFCATLFYALTGHMPKSAVERRKDSRLLMSTTTVKRL
                     PPHVVSALANGLQVERENRITDFDELRSQLSVAHTAKAIQDEISRTASMNLTKSERTRK
                     TSNGMSHASIIIIAAAITVLVLGIAGVFWLMQNPLAGMFSNNTDASVSSTQSTEWTGAT
                     VPNYIGMTYEEAVKSVDSNSSITIYRTFNDEYSDDYAEGKIMSQTPAAGSKITQEDSVV
                     VSVCVSKGSQMRTLPKVEGEKLDTVASDIAAQGLLATAEYEYSDKVAEGRVIRYKEHVE
                     GDTLEYGSTVVLVVSKGKKQTSSQSSNR"
     CDS             complement(7642..8292)
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MADKGVIMRCVIIAGSPDTNSDFLSEVIKPDDYVICADRGCNFAK
                     QAGITPNLVVGDFDSEPDVLFPNCETVRLIPEKDDTDTMHSVDLALEKRFDEIAILGAL
                     GGRFDHSFANVAVLSYIHEHGSKGVLLSEKEKIEFLPVGHYEYKNFKGKTFSLFPFGCP
                     SVCVSYSGTKYPLEKYCVSSSVTLGVSNVFTSDMTTIDIYDGNAILIINLIDC"
     CDS             complement(8274..9137)
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MKSIGGFYYVRADGEDYECKARGSFRKSGNSPVAGDKVNISVPND
                     GFCAIEEILPRKNKLRRPALANLDILLLVCSTVEPLPNFTIIDKMTAAAVNNNMEPVIV
                     VTKNDLENGDKIADIYRHAGFEVFLCSEDDSSQTEELKSYLSGKVSAFIGNSGVGKSTL
                     LNKLFPSLSLETGQTSKKLGRGRHTTRVVELFELDGCFVADTPGFSTVDLQRYEMIDKS
                     RLQYCFPEFEKYLGECMFTSCSHTCEKGCRILEALSDGEIEETRHRSYVQMYNEVKDIK
                     SWQIKE"
     CDS             complement(9172..11277)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 259.2;
                     E-value: 6.9e-79)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_11"
                     /sec_met_domain="Pkinase (E-value: 3.8e-61, bitscore:
                     198.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKYLGKRLDGRYEIHELIGVGGMANVYRCTDTVDDREVAVKILK
                     DEYLNNEEFIRRFKNESKAIAMLSHPNIVKVYDVSFGDMIQYIVMEYIDGITLKEYIDQ
                     QGIIEWKDAIHLTAQILKALQHAHECGIVHRDIKPQNIMLLQDGTIKVTDFGIARFSDK
                     STRTMTEQAIGSVHYIAPEQARGDATDGKTDIYSVGVMLYEMLTGKLPFDGDSAVTIAL
                     MQLQSTPKHPREINPGIPIGLEQITMKAMEKLPSDRYTSAAEMLSDIERFRLNPSIVFD
                     YGNKSFVDNQPTKFVHSLRDGRVRNKIDNEATKVVDMPQDDVVVKEEQFADEDFVKEHK
                     PSYYAVKGIVIAAVAVCAIFFALAMFRGCSTSQAKDVEVPDYVGKSFVSIKENNPNDFK
                     FEVKSEYDESKEMGVILDQEPKGGSMKVKSGSTITVTVNGTDTEVSVPYVTNYSEKEAS
                     QALKEKNLIPEIVYVENTKTPKGYTIECFPKAGVKTTIGSTVYVYIASGERTKQVTLPS
                     VDGLMLSEAKQTLVDLGLTVETVQDDESKEPKDTVLGMSPLQYGKVDAGSVVTLTVSSG
                     LGDENTVNIFVDLPSDVEDSVDMTVIVDGAVDSRNSKTLVPKYNKTYTLELKGSGTSTV
                     VIQLDGQAYREYSVDFASAAVTTTASHDYVRATTAPPETEPSTQYYTDPYVAPDTTVQP
                     VTDDPEL"
     CDS             complement(11296..12021)
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MEVFSKSDIGLVRNQNQDDCRFGVISPSCVWAVVCDGMGGANGGN
                     IASATAVDYISTKITDLYKDDMTKEQIGELMAEIVVNANMKVFEMSMKDPELTGMGTTC
                     EFVFVKDTTVHVVHVGDSRTYAIRGGKIKQLTEDHSVVQEMVRRGELTYEQAQNHPNKN
                     FITRALGIKPSVRLDYIEANFIYGDVLLICTDGLSNCVTTGDMVKICHENRGEGLITKL
                     VDKAKDGGGSDNITATVIY"
     CDS             complement(12023..13039)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_13"
                     /sec_met_domain="PF04055 (E-value: 8.8e-26, bitscore: 82.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDELTEFVTENGFPKFRAKQIYDWLYKNVTDFDNMRNIPADLK
                     AFLKSSSYISVANIEKKLVSRYDKTVKYLFSFNDGECVESVVMSYKHGYSICISTQVGC
                     KMGCTFCATGKSGFSRSLAPSEMLGQIEAAQRDLNIRISNIVLMGMGEPLDNFDNVVKF
                     LRLVSSDNGLNIGMRHITLSTCGIVPKIYELAKLHLGITLSVSLHAPNDEIRQRTMPIA
                     RKYSIEELLKACSDYFKATGRRVTFEYSMISGVNDSDENARELAKRLEGTQSHVNLIPV
                     NTVEGTGYLKSNIKRQQAFINILAAKNIGATVRRTLGSDINASCGQLKRKHIEEGGK"
ORIGIN
        1 gttagcaagg tcaaatctca tacaaacgag cttaattgga tcggcaatgg aatgtatgac
       61 ggcagtatcg gacagttctt tgaactgtac ttcaacttct atatgcagat tcttttcatt
      121 gcgtttgcgg caggaattta cttcttgttc attaacagaa agacaaatat tgaaaccgta
      181 cttctccctc ttgttattct gggagcgttc ggatatcacc tcttatttga aggcaagtcg
      241 cagtatgtgc tgacttacat aattcttatg attcctactg cgtcttttgc atttgagtgt
      301 attcttaacg gcaaatatac aaaaatcaaa gaatttgtcg gaaaactgaa agaaattccc
      361 gacggtaaag aaagcgaaaa agcctgataa aatgattgaa gcggacagtt aatcatgtcc
      421 gctttttctt tgctcttttt tgacaaatgc aatacccgta ctgccctctc ctatatgact
      481 gccgacaacg gaacccacgc tgacaatact gccctcaaca aaaggaattc cttttgatat
      541 tatgagcttt gataaataca atgcctgatt ttttgcgttt gtgtgcatta tatacagcgg
      601 ataattttgg tctatgccaa gctttttcag cgacatcagc atatgattca taccgtggcg
      661 cattccaatt gttttcgcct caaaggctac actgcccgaa cccgtaatgc tgattacggg
      721 ttttattctt cctgttgagc cgagtaatgc ggcggcattt gtatgtctgc cacccccata
      781 gaggtacttc atatcgtcaa tacaggcata taccataatt ctgcttctga acctcagaag
      841 atgttcggca atttcttttg ctgtaaaccc gttgtcacgc aagcgaagtg cctcgtttac
      901 aagaagcttc tgacctgccg aagcagattt gctgtctatc acataacacc cctcatatcc
      961 gagcaaatct cttgcaagaa ctgcactctg atatgaaccg ctcaatgccg aagaaacagt
     1021 tatcaccaca accgattcgc cgttatctct cgcctttttc aaagcacatt cgtagacata
     1081 cggcgagggc tgagaggttt tcggcaaagt tttcgacagc tttgcaagcc tgtaaaagcg
     1141 ttcctttgaa tgtaaaaaat catccttata ttcttttccg tcaatatata cagctaacgg
     1201 aactgtagaa attccgaatt tttcactttc tgaatgttca aaatcggcgg ctgaatcggt
     1261 aataattctg accatttagg tatcacctca aaaataatat cttaaaatat tattttcaaa
     1321 tttgccttta ttatgcaaaa atcccgacag caaaaactgt cgggaggttg atttgcatat
     1381 tcaatttccg aaattattta tcccaatacc gtcaaagccc atttcatcca aaagggactt
     1441 gtacaaattt acatcttcat ccgtgtatga catacggttt ttgatacccg atttaaaatt
     1501 gatatttctg tctacaaaaa gcctttttcc ccacatatga caccatgaaa tcggtaaaag
     1561 gaacggtgtt tttttacata tggatactta tactgcattt cggattttgg tggaaatatt
     1621 gaggacacaa gatatgagaa ttttgatttg ttattttctg taattgtctt gtgagaattt
     1681 atcatcgtgc caacatctac cctgccgagt gtaccgctga gcagaatata ttcttcgata
     1741 tcatcaaatt taagttcagc ctgtggcttt gaaaaccagt tgaacgcaat ctcacgaaca
     1801 cgcttttcat actttgcaat accgattttt tcaagcatca cattaagata gtcataatca
     1861 agctcagatt gatgattttt caagaagaca tagctgtcaa gcaccattcg gattcccatt
     1921 ccaccgattc tgaaatgatt tgagttatga acaagcatat agatataaaa gtcctcatgg
     1981 ctcatttcat atgaatagct gtagccgtca cgccttgttg aacggtcaag ctgattaaca
     2041 agcaacggat aggattcctc gttttcgtgg acaagagttg catgcatttc aatgttcatc
     2101 atcggttttt tttcaaaatg atactggttg tcatcttcat tcagaaaagt gtatccaagt
     2161 ttggaaaata cttttttgac caaatcagcc tgttttctgt caaaaaggat atctacatcg
     2221 gacacggaac gaaagtcgga gcgaggatat tcctttttca taaaatagcc ctttaaggga
     2281 atattcttga ttttgttttc atcaaaagcc ttgagaattt tctcggtttc atatgagaga
     2341 tttccatcaa tcagcatttc aaccgacaaa tcctgcttga atttttcata tacttcgggt
     2401 gaaacatact ttttgtcgag cgacaaaacc gcattggcaa caaacgattc aacactgcaa
     2461 tagtttgcaa gcatttttat cgactgccat tttatcccct cgtaaggaat cggaggtgct
     2521 gttccgttta cagacgatga aacaagctca agcagatact taaattcaat tttttcgtta
     2581 tcgttaagat gtttcctcat ttttcccctt ttttcgtttt aagctttgag aatgcatttt
     2641 tacttcttga cacagttgat gcaataacct ttcttagcgg ttttgaatag aacataaatt
     2701 caaggtatgc tctgtacttc attgagtcaa ccgtgtaggg cttgcccttt ctgtaaaaag
     2761 ctgttaccac tccgattaca tcatcatcgg taataccttt ttcaacggca aactgattgt
     2821 caccgcacat agtataactg ccatcacttc cgaaattgac aacacggtgc aatacatacg
     2881 agccgtcttt tcgcctgtat aaaggcaagt caaaaagatg aagtctgccc ttcggttttg
     2941 ataaaacaac agtatcgtca ccgtctcgga gcattgggag catacttgtt cccttcggat
     3001 tgaaagtaac cgatcctcca gcctcaagct tttcggctat aatctgcatt acatcatcaa
     3061 gacctacttc tttattcaag gacatcagcc tctcttagct tttgaataaa tgtatcaata
     3121 tcggcactcg ccttttcttc gctcacttca tactcatcaa gcattgcttt gagcaaatca
     3181 gccttttcgc aatcgttttg gagcttttca aaaaggaatg cacccgtttc attgaggttg
     3241 ataattccgt taaaatcaag cgtcagcttg tttacaggaa ctacaacata tgaatctgca
     3301 acctttcgca ggacaaaatc ttcttttatc ttcataaaat cacctgtttt ccgtgtgaat
     3361 tttttcatca atatttaaat tataatatac ctttcgacaa aaagcaagaa aaaggatttg
     3421 agcataaaat taccgcagac cttttgagtc tgcggtaaaa tttatctaca atattataag
     3481 cttacgggat tagtacattc cgcccatatc aggtgctgcg ggagctgccg gagctgccgg
     3541 ctctttgatg tctgtaacaa gtgattctgt tgtaagaacc attgctgcaa cagagcttgc
     3601 gttctggaga gctgaacgag taacctttgt tgggtcaacg atacctgccg aaaccatatc
     3661 tgtgtattcc tctgtaagag cgttgaagcc atagccaacc ttgttagcct tcttaacatt
     3721 atcgcagatt acgctgccct caagacctgc gttagcaaca atctgacgga gcggttcttc
     3781 aagtgcttta agaacaatct tagcacctgt cttagcgtca ccctcgagag tgtcaacaaa
     3841 ctcagcaaca gccggaatag cgttcatgca agcgataccg ccgcctgcta cgataccctc
     3901 ttcaacagca gcctttgtag cggcaagagc atcctcaata cggagcttct tttctttcat
     3961 ttcaacttct gttgcagcac caaccttgat aactgctacg ccgcctgcga gctttgcaag
     4021 acgctcctga agtttttcac ggtcaaagtc agatgttgtt gtttcaatct gctgtctgat
     4081 ctgagcaact ctgcccttga tagcttcctt gtcacctgag ccgtcaacga tgattgtgtt
     4141 ttccttttca atcttaacct gacgggcagt accgagctga tcaactgttg tatccttgag
     4201 ttcaagaccg aggtcagatg tgattactgt accacctgtg agtgttgcga tatcctgaag
     4261 catttctttt cttctgtcac caaagcccgg agcctttacg gcaacacaag tgaatgtacc
     4321 tctgagtttg ttaagtacga gagttgtaag agcctcgcct tcaacatctt cagcgataat
     4381 aaggagcttc ttacccatct gaacaatctg ctcaagaagt gggagaattt cctgtgtagt
     4441 agaaatcttc ttatctgtga taaggataag cggattgtca agctctgcaa ccatcttatc
     4501 tgtatctgtt accatataag gagcgatgta acctctgtca aacatcatac cttcaacaac
     4561 ctcgctgtat gtttcggctg tctttgactc ctcaactgtg ataacaccgt ctgttgtaac
     4621 cttttccata gcctcggcaa taagcttgcc gatgaattca tcctgtgatg aaactgttgc
     4681 aactcttgcg atatcatctg taccggatac ctgcttgctg ttcttcttta cagcctcaac
     4741 tgcaacattt acagcgtctg caataccctt tttaagtacc attgggttag cgcctgcagt
     4801 tacattcttc ataccctctc tgatgagagc ctgagcaaga agtgtggcag ttgttgtacc
     4861 gtcgcctgcg atatcgttag tcttgataga aacttccttt acaagctgag cgcccatatt
     4921 ttcaaaagga tcttcaagtt caatttcctt agcgattgtt acaccgtcat ttgtgatgag
     4981 cggagcaccg aacttcttat caagaacaac atttctgccc ttaggtccga gtgtgatttt
     5041 aacggtatca gcgagctggt cgataccttt cattaaagct tttcttgcat cttcgccgta
     5101 tgcgatttgt ttagccattg taaattacct ccgtatattt agttaattat tcaagagttg
     5161 caagtatatc cgactggttt acgattgtgt attcttcgcc gtcaatcttt acctgtgtgc
     5221 ctgcatattt acttgcgata accttatcgc ctacgctaac atacatcttt acttccttgc
     5281 cgtcaacaac accgccgggg ccaacagcaa caactgatgc gaactgtggc ttttcctgag
     5341 cagcagatga aagaatgata ccgctctttg ttttctcttc agcctcttca acttttaaaa
     5401 cgactctgtc gagtaatggt ttgattgtca taaatacagc ctcctgtaaa aattttaaat
     5461 tgcttttaat caattagcac tcttgttccc tgagtgctaa ttatatttta taccattttc
     5521 aagaaaagtc aagagaaatt tgactatttt tgacctttat tttgtgacag ttttctgaaa
     5581 ctttttccaa tctctatttt atcgagtatt ttaagataat cagtaactat aactgttttg
     5641 tatcaataaa aaagacggac tgcaaaaagt ccgtcttaaa cattgttatt aattctatct
     5701 gtttgatgat tgagaacttg tctgtttctt gcccttgctg acaacaagaa ctaccgttga
     5761 accgtattcg agagtatcac cctcaacatg ttctttgtag cggattaccc ttccctcagc
     5821 aaccttgtca ctgtactcat attctgctgt tgcaagaagt ccctgagcgg caatgtcgga
     5881 tgcaacggta tcaagttttt caccctcaac cttcggcaga gtcctcatct gtgatccctt
     5941 gcttacgcaa acactcacta ctacggaatc ttcctgagta atttttgaac ctgcggcagg
     6001 agtctgtgac ataatcttac cttctgcata atcatcgctg tactcatcgt taaaggttct
     6061 gtagattgtg atactgctgt tgctgtcaac actcttaaca gcctcttcat atgtcattcc
     6121 gatatagtta ggaacagtag cacctgtcca ctctgtgctt tgagttgagc ttacactcgc
     6181 atcagtatta ttcgaaaaca ttccggcaag cggattctgc ataagccaga acacaccggc
     6241 aataccgaga acaagaaccg tgatagcagc cgcaataata ataattgaag cgtgtgacat
     6301 accgtttgaa gtcttgcgtg tacgctctga ctttgtgagg ttcatgcttg ctgttcttga
     6361 aatttcgtcc tgaattgcct ttgctgtatg agcaacggaa agctgtgaac gaagctcgtc
     6421 aaaatctgta atacggtttt cacgctcaac ctgcaaaccg ttagcaagag ccgaaacaac
     6481 atgcggagga agtctcttta cggttgttgt actcataaga agtcggctgt ccttacggcg
     6541 ttctaccgca ctctttggca tatgacccgt gagggcatag aaaagggttg cacaaaatcc
     6601 atagatatcc gtaatatcgt caagaggaaa attatcgtca tactgttcgg gagccgcagc
     6661 gcctgagaaa agctgagatt tgagaggcgt gcctctttta cgctcatttt ccgacgcaaa
     6721 gcctgaaatt ttaattttac ccgatgctgt gatatacata ttcttaggtg cgatagcata
     6781 gtgaccgaca cctctcttgt gaagagcctc aagcgcagaa attacaggca taaaaagcgg
     6841 acgggcaata tcccattcaa gatgaccgtt actgcgttca acatactcct caaaaggaat
     6901 aagatcctcg ttttcctcaa caacataaac tgtgttattt tcttcaaaaa tgttgtgaac
     6961 attcataaga gcggaaagct cacggagttc tgaaagaatc ctgtaatagt taagaaaatc
     7021 gtccttgagt ttattatata caaggcggtt ttcataattt attctgacct cggtagttcc
     7081 ttcttcacga gaaaaaagtc cgataggaag aaattcgcag atgattacaa tgtcacctgt
     7141 ctgcttgtcg tggcttatat agcgtgtgct ttcgccgttg gtatcaattc ccgcacctac
     7201 gatatagcgg ttctgaagaa ttgttccgta cggtaaaaaa ggagcttgct gtttttcagt
     7261 tgtatcaaat ccgcaggacg gacaaatctt gttgtcacct atttcctgca tgcatcccat
     7321 acacaatgac atattattac tcaactccaa ataagtatca atttcaaatt ttgtctgaaa
     7381 agaattatac cataaaaaca tatttctttt caagacttaa aggtgttaat atagttacaa
     7441 ttttgttatt gcaaagcctt ataaagcaaa ttctttgcaa atattgttgt ataaaaaatg
     7501 tggtggagat aacggggctc gaacccgtga ccttctgact gccagtcaga cactctccca
     7561 gctgagctat acccccatat aatgttgaca ttgcttttga catatacaag atacatttgc
     7621 aaacaatgtc aagctgtaat tttaacagtc tatcaaatta attataagta ttgcatttcc
     7681 gtcatatatg tcaattgttg tcatatcgga agtgaataca tttgaaacac ccagagtaac
     7741 gctgctcgaa acacaatatt tttcaagagg atactttgtt cccgaatagc ttacacagac
     7801 actcggacat ccgaaaggga aaagcgaaaa tgttttgcct ttaaagtttt tatattcata
     7861 atgacctacg ggaagaaatt ctattttctc tttttcagaa aggagaacgc ccttacttcc
     7921 gtgttcgtga atataagaga gaactgccac atttgcaaag ctgtggtcaa agcgaccgcc
     7981 caatgcaccg agaattgcta tttcgtcaaa ccttttttca agtgcaaggt caacagagtg
     8041 cattgtgtcg gtatcatcct tttcgggaat aagtcggacc gtttcgcagt ttggaaacag
     8101 tacatcaggc tcggaatcaa aatctcctac aacaaggttc ggagtaatgc ctgcctgttt
     8161 tgcaaaattg cagcctctgt cggcacatat cacatagtca tcaggtttta taacctcgga
     8221 caaaaaatcc gaatttgtgt caggcgagcc tgcaataatc acacaacgca taattactcc
     8281 tttatctgcc atgatttaat gtccttgacc tcgttataca tctgaacata actgcgatga
     8341 cgggtttctt caatttcacc gtcagagagc gcctcaagaa tcctgcagcc tttttcacag
     8401 gtatgcgaac atgaagtaaa catacactcc cctaaatatt tctcaaattc aggaaagcaa
     8461 tattgcagcc ggcttttgtc aatcatttcg taacgctgaa gatcaacggt tgaaaatccg
     8521 ggtgtgtctg ccacaaaaca accgtcaagt tcaaacaatt caacaactct tgttgtatgt
     8581 cttcctctgc cgagtttttt gcttgtctgc cctgtttcaa gagaaagcga tggaaaaagc
     8641 ttattgagca atgtggactt gccgacaccg ctgttaccga taaaggctga aaccttgccg
     8701 gacagatagc ttttgagttc ttcggtttgt gaagaatcat cttccgaaca gagaaaaacc
     8761 tcaaaacctg cgtgtctgta gatatcggca atcttatctc cgttttccag atcatttttt
     8821 gtaacgacaa ttacgggttc catattattg tttaccgccg ccgcagtcat tttgtcaata
     8881 atcgtaaaat tcggcaacgg ttcaacagtt gaacacacga gaagaagaat atcaagattt
     8941 gcaagagcag gtctgcggag cttgtttttg cgtggaagaa tttcttctat cgcacaaaaa
     9001 ccgtcattcg gaacagatat atttaccttg tcccccgcta cgggagagtt tccgcttttg
     9061 cgaaagctcc cccttgcctt acattcgtaa tcctcaccat cggcacggac atagtaaaat
     9121 ccgccgattg atttcattaa aattccgctt ttagtatcca tacttcaccg attaaagttc
     9181 aggatcatcc gtaaccggct gaacggtcgt gtcaggcgct acatacggat ctgtgtaata
     9241 ctgtgtcgac ggttcggttt cgggaggagc ggttgtcgca cggacataat catgtgacgc
     9301 cgtagtggtt accgctgccg atgcaaagtc aaccgaatac tctctgtacg cctgaccgtc
     9361 aagctgaatt actacagttg aagtgcctga gcccttgagt tcaagagtat aggtcttgtt
     9421 atatttcgga acaagcgtct ttgaattgcg ggaatcaacc gcaccgtcaa caattacagt
     9481 catatcgact gaatcttcaa catccgacgg aaggtcaacg aagatattaa ccgtgttttc
     9541 gtcaccgagt cccgagctta cagtcagggt tacaacagag cctgcgtcaa ccttgccgta
     9601 ctggagaggc gacataccga ggactgtatc ctttggttct ttgctttcat catcctgtac
     9661 tgtttcaacg gtaagtccga gatcaacaag agtctgcttt gcttcggaaa gcataagtcc
     9721 gtcaaccgac gggagtgtaa cctgtttggt tctctcaccg cttgcaatat atacatatac
     9781 cgttgaaccg attgtagttt ttacacctgc tttcgggaag cactcaattg tgtagccctt
     9841 tggtgtttta gtgttttcta catagacaat ttcaggaata agattctttt ccttgagagc
     9901 ctgagaagcc tctttttcgc tgtaattggt tacataagga acagaaacct ctgtgtccgt
     9961 tccgtttacg gttaccgtga ttgttgagcc tgacttaacc ttcattgaac cgcccttagg
    10021 ctcttgatca agaattacgc ccatttcctt tgactcatca tattcactct taacctcaaa
    10081 cttgaaatca ttcgggttat tttcttttat tgaaacaaag gatttgccga cataatcggg
    10141 aacttcaaca tccttagcct gtgaggttga gcagcctctg aacattgcaa gtgcaaagaa
    10201 aattgcacat actgcaacag ccgcaattac aatacccttg actgcatagt aggaaggctt
    10261 atgttccttt acaaaatcct catcggcaaa ctgttcttct ttaacaacaa catcgtcctg
    10321 cggcatatca actactttgg ttgcctcgtt gtcaatttta tttcttaccc tgccgtcacg
    10381 cagagagtga acaaactttg tgggctgatt atcaacaaaa gacttgttgc cgtaatcaaa
    10441 aacgattgac ggattaagtc tgaatctttc gatatcagaa agcatttctg cggcagaagt
    10501 gtatctgtcg gacggaagct tttccattgc cttcatagta atctgctcaa gacctatcgg
    10561 gattcccgga ttgatttcac ggggatgctt cggtgttgac tgcaactgca taagcgcaat
    10621 tgtaacggca ctgtcaccgt caaacggaag ctttcccgta agcatttcat agagcattac
    10681 accgacagaa taaatgtctg tttttccgtc agttgcgtca cctcttgcct gttcaggggc
    10741 aatgtagtga acagagccga ttgcctgttc tgtcattgtg cgtgttgatt tatcggaaaa
    10801 tcttgcaata ccgaaatcgg taactttgat tgtaccgtcc tgcaacagca taatattttg
    10861 cggctttata tcacggtgta caattccgca ctcgtgagcg tgctgtaaag cctttagaat
    10921 ttgtgcagtc aggtggattg cgtctttcca ctcaataatg ccctgctgat caatatattc
    10981 tttgagggta atgccgtcaa tatattccat tacaatatac tgaatcatat cgccaaagct
    11041 tacatcatat acctttacga tattcggatg tgaaagcatt gcgatggctt ttgattcatt
    11101 tttgaaacgg cggataaact cctcattgtt gagatactcg tctttaagaa tttttacggc
    11161 aacttcacgg tcatcgactg tgtcggtaca acggtaaaca tttgccatac cgccgacacc
    11221 gataagctcg tggatttcat atcttccgtc aagtcttttg cccaaatatt tatccaaaac
    11281 ggtcaactcc tatccttagt aaattacggt agctgtgata ttatcagaac ctccgccgtc
    11341 tttcgccttg tcaacaagct ttgtgataag accttcgcca cggttttcat ggcagatttt
    11401 gaccatatct cctgttgtga cgcaatttga aagtccgtcg gtacagatga gaagaacatc
    11461 accgtaaata aagttggctt caatatagtc aaggcgaacg gacggtttta tgccgagcgc
    11521 ccttgttata aagttcttgt tcggatgatt ttgcgcctgc tcatatgtaa gctcgcctct
    11581 tcgaaccatt tcctgaacaa cggaatgatc ctctgtaagc tgcttgattt taccgcctct
    11641 gatagcgtat gtgcgactgt caccgacatg aacaacatga acggttgtat cttttacaaa
    11701 gacaaattca catgtagttc ccatacccgt gagttcggga tctttcatgg acatttcaaa
    11761 gactttcata ttggcattaa caacaatttc tgccataagc tcgccaatct gctccttggt
    11821 catatcatct ttgtacaaat cggtaatttt ggtgctgata taatcaacgg ccgttgcgct
    11881 ggcaatatta ccgccgtttg caccacccat tccgtcacac acaactgccc agacacagct
    11941 gggagaaata actccgaagc gacagtcatc ctgattctga ttacgaacaa gtccgatatc
    12001 acttttgctg aatacttcca agttatttac ctccttcttc aatatgcttt cttttgagct
    12061 gaccgcacga tgcgtttatg tcacttccga gtgttctgcg cacggttgct ccgatatttt
    12121 tagcagcaag aatatttatg aatgcctgct gtcttttaat attgcttttt aagtagcctg
    12181 ttccctcaac agtattgacg gggatcagat taacatggct ttgtgtaccc tcaagtcgtt
    12241 ttgcaagctc tcttgcgttt tcatcgctgt cattaactcc gcttatcata gagtattcaa
    12301 atgtaactct gcgacctgtt gctttgaaat aatctgaaca agcctttaat aattcttcaa
    12361 tagaatattt tcttgcaatg ggcattgttc gctgtcttat ctcatcgttc ggcgcgtgta
    12421 atgaaacgga aagcgttatt ccgagatgaa gttttgcaag ctcataaatt ttcggaacta
    12481 taccgcaggt tgagagcgta atatgtcgca ttccaatgtt aagaccgttg tcggacgaaa
    12541 caagtcggag aaattttact acattatcaa aattatcaag cggttcaccc attcccataa
    12601 gaacaatgtt agaaattctt atgttaaggt cacgctgtgc ggcctcaatc tgtccgagca
    12661 tttccgacgg tgcaagactc cgtgaaaaac cgcttttgcc tgttgcacaa aatgtacaac
    12721 ccattttaca gccaacctgt gttgagatac agattgaata tccgtgtttg taactcatta
    12781 caacagactc tacacattcg ccgtcattaa acgaaaaaag gtacttgact gttttatcat
    12841 accttgaaac aagttttttt tcaatatttg caacagaaat gtaactactt gatttcaaaa
    12901 aagcctttaa atcggcagga atgttacgca tattgtcaaa atcggtcaca tttttgtaca
    12961 accaatcata aatctgcttt gctctgaact ttggaaaacc gttttctgtg acaaattcag
    13021 tcagctcatc aagcgtcatt gacttgatat ccgttaaatt attcaatttg acgccttctt
    13081 tccgaataag ctgatgtaaa atccgtctgt tccgcaggtg tgcggcataa gtgttatttc
    13141 gtatggttct tcatcaaatg cacgggtaat tccgtttgga agttttaacg gtattccgta
    13201 aaaatcggga tgttcctcaa gaaaacgctt tgtgttttta ttgttttcat caggattcaa
    13261 tgtacaggta gaatagacaa gcttaccgcc tactgcaaga ttatccgcac ttgcacagag
    13321 aatcctgtac tgcaa
//
