LOCUS       c00006_gnlPro..        13912 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ENJKBHIJ_6.
ACCESSION   c00006_gnlPro..
VERSION     c00006_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:30:12
            Original ID  :: gnl|Prokka|ENJKBHIJ_6
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13912
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13912
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[351:3912](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(352..3912)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13912
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13912
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(352..3912)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_1"
                     /sec_met_domain="PFOR_II (E-value: 7.4e-19, bitscore: 59.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.2e-81, bitscore: 265.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.3e-32, bitscore: 104.7,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.6e-14, bitscore:
                     43.0, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 5.7e-11, bitscore: 34.7,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.5e-07, bitscore: 21.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3e-09, bitscore: 28.2,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00017, bitscore: 13.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 8.9e-21, bitscore: 65.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LARKMKTMDGNSAVAHVSYAFTDVAAIYPITPSSVMADLTDKFSA
                     QGAKNLFGRQVQVTEMQSEGGASGAVHGSLAAGALTTTYTASQGLLLMIPNMYKMAGEL
                     LPGVIHVSARALTSHALSIFGDHSDIYACRQTGYAMLCSNNPQECMDLAAVAHLAAIEG
                     RVPFLHFFDGFRTSHEIQKIEEWDYADLADMLNWDAVEAFRRRALNPEHPVTRGTAQND
                     DIFFQAREACNKYYDAVPEVVVKYMDKVNAKIGTDYKPFNYYGAEDAEHVIVAMGSVCD
                     CTEEVVDYLNAAGEKVGLLKVHLYRPFVADYMLRELPKTVKTISVLDRTKEPGSIGEPL
                     YLDVLAAINGSDFAGVKVYTGRYGLGSKDTTPGDIIAVYRNAESETPKRRFTIGIVDDV
                     TNLSLPIVENPDTTPKGTHSCKFWGLGADGTVGANKNSIKIIGDNTDMYAQGYFAYDSK
                     KSGGLTVSHLRFGKTPIKSTYYISKADFVACHNPSYVDKYDIVDDLKEGGSFLLNCPWD
                     TEELSERLPGKMKKILAERHINFYTIDGIKIGKEIGLGGRINTVLQSAFFKIADIIPAD
                     KAKELMKAAAKKSYMKKGQAIVDMNYAAIDRGMEDLKKVEIPADWANAVDNSTADKAEG
                     NGALVEYVNEILKPVNAYKGNKLPVSTFMDHVDGTAPNGSAAYEKRGIAVDVPEWNPEN
                     CIQCNRCAIVCPHAVIRPVAMTADELAKAPEGTKSLPMMGLKDLNFVMTVSTLDCTGCG
                     ACAQVCPGKKGAKALTMQPIDSQRPKQAVFDYALTLEDKPEVHEKFKFTTVKGSQFKQP
                     LLEFSGACAGCGETPYAKLVTQLFGDRMFIANATGCSSIWGASAPATPYTKNKKGYGPA
                     WQNSLFEDNAEFGLGMALGQKAIRNRLIEYVEGIQKDTDSADLKTACQNYLDTVTDSTS
                     SRPATDALIAELEKNTEDAKVGELVKKTLVDKDELAKKSMWIFGGDGWAYDIGFGGLDH
                     VIASGENVNILVFDTEVYSNTGGQASKATPVGSVAQFAAAGKAVKKKDLAAIAMSYGYV
                     YVAQCAMGADNNQVLKAMVEAESYNGPSLVICYAPCINHGIKGGMGIAQLEEKKAVEAG
                     YWNIFRYDPRLADEGKNPFMLDGKAPSASYRDFIMGEVRYNSLTRSFPERAEKLFEKAE
                     KVAADKYAHLEKLASLPDAE"
     CDS             complement(4298..4705)
                     /locus_tag="ctg6_2"
                     /transl_table=11
                     /translation="LQRNDFVVKLNKNRDLTTGSITGGLRSFAVPLMLCNVFQQFYNLA
                     DTWMVGKYAGDNALAAVGSSYTLLTFLNSVIIGLEPVDCVAFEDSINGIKSAHAAGMTT
                     VMVPDLSEPTDEIKPMIDFLCTDLSEAIKHL"
     CDS             complement(4721..5137)
                     /locus_tag="ctg6_3"
                     /transl_table=11
                     /translation="MRGLFNRFANFMQGRYGTDKLNNALWVLLLILWFVNIFVWNRVAR
                     YIIDGIMLLIIVLICFRMFSRNIVARSAENRKFLPIYNAVTGWFKLTFKKIRDRKDYRY
                     IKCPVCKAQLRVRNKKGNHTVRCPKCGSEFNKKI"
     CDS             complement(5247..7661)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) B12-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pterin_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_4"
                     /sec_met_domain="B12-binding (E-value: 2.3e-21, bitscore:
                     67.5, seeds: 91, tool: rule-based-clusters)"
                     /sec_met_domain="Pterin_bind (E-value: 8.8e-42, bitscore:
                     134.8, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNIVVFKNFSNFSEYLNQKNFILLDGATGTLIQKSGVKYDHVPE
                     VLNITHPELIESFHRRYIDAGSDIVYANTFGANAYKLQDSGYSVEEIIGAGVKIARKAV
                     EGTDALVALDIGPIGQLLEPAGSMKFDEAYEYYKQQILAGKDADVIVFETMTDLYELKA
                     AVLAAKENCDKPILTTMTFERNGRTFTGVSPACAAVTLTGLGVDALGVNCSLGPDELEP
                     VVSEMSKYTNLPLVIKANAGLPDPNSNEYNIMPDKFAECVCSLLKYGVKVIGGCCGTNP
                     DYIAKIKSEVADREYQPQTKSVDTTVCSSTTVVEINGPRIIGERINPTGKKLFKQALVE
                     NNIDYILTQALSQVQGGAEILDVNVGHPEIDEKKMMVRVLKAIQSVCDVPLQIDSTKPE
                     VIEAGLRYYNGKPILNSVNGEEQSLATVLPLVKKYGASVVGLALDENGIPKTAEGRFEI
                     AKRIVERAEAVGIDRKDVYIDCLTLTVSAEQAACRQTLEALHRVKTELGCKTCLGVSNI
                     SFGLPNRELVNRTFLTMAMEQGLDLPIINPNVESMTGAVRAFRVLNGIDKNSLEFINAY
                     NDAVPAAPVKKADSNVDIFAAVYNGLKNEGAAATAKLLETTDAMQVVNEMLIPALDRVG
                     EDFEKNKIFLPQLIQSANTAQECFDVIKKHLTKTSGTPVSKGKIIVATVKGDIHDIGKN
                     IVKVLLDNYGYTVVDLGRDVDPQLIVDTAVEQNITMIGLSALMTTTLKSMEDTIRLVRE
                     CKELQNPDGSSKCTIFVGGAVLTKDYAMKIGADYYCRDAKESVDTAKLVLG"
     CDS             complement(7639..8283)
                     /locus_tag="ctg6_5"
                     /transl_table=11
                     /translation="MITLDRLNRKEAIRYLGGAGISLNYRMDVLMDECEKEILKTAEPR
                     FLYVERKAPFDDILLGNDIKKHLEGCHTAVMMCATIGSEIDKLIRISQISDMARAVVLD
                     SFASVAVEQVCQKVDEILAEKYSGKYMTFRFSPGYGDYPIEMQKEYLRILDAPRKIGLT
                     TGDSCLLVPSKSVTAVLGISDNPIERRKRGCAICSMKGKCRFRRNGEHCGV"
     CDS             complement(8280..9140)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MTHFR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_6"
                     /sec_met_domain="MTHFR (E-value: 1.8e-85, bitscore: 278.1,
                     seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISNLFNGGKTVFSFEVFPPKKTSPIESVYGKLEEISALKPDFI
                     SVTYSAGGSGSKSRTCEIATKIKRDFGVESVAHLTCINSTKADIDRNLALFKENGIENI
                     LALRGDRVEGVEPQKDFTYASDLCRYIASQGDFDIAGACYPEVHSEATDEVEDIHNLRK
                     KVESGASHLISQLFFDNSAYYRFLERAKIAGVNVPIEAGIMPVTSKSQIERMVSMCGAS
                     LPAKFAKIMQKYDTRPEALRDAGIAYAVDQIVDLIAHGVDGIHLYTMNNPYVARKITEA
                     VSSLL"
     CDS             complement(9536..10903)
                     /locus_tag="ctg6_7"
                     /transl_table=11
                     /translation="MEQVNVTLTETIKVLLDDKKFSTLRDILITMKPFDIAAVFENLQD
                     EKMPILFRILPKELAAETFVEMDDETQEFLIHGFSDSELKEVVDELFVDDAVDLIEEMP
                     ANVVKRILRQADKDMRKQINELLKYPEDSAGSIMTTEFIVLRPDMTAEMAIKRIRRTGV
                     DKETIYTCYVTDANNKLIGITTVKDLLLAEDDELVKSIMEENVISVTTLADQEQVAQMF
                     SNYNFLALPVVDNENRLVGIVTIDDAIDVIQEEATEDIEKMAAVLPSDKPYMKTSVFGL
                     YKKRAPWLLILMLSATFTSAIISSFEAVLANVLILSSFIPMITGSGGNAGSQASVSVIR
                     ALSLGEIHFRSIFLVLWKEFRVSILCGITLAAANFVKLLLFDLNGQENAFMIALVISLT
                     LVGTIIMAKLVGSSLPLLASKVGFDPAVMANPLISTVCDSLSLLIYFGVAKLILHL"
     CDS             11327..11968
                     /locus_tag="ctg6_8"
                     /transl_table=11
                     /translation="MTDMVKKYVPYAVIILLVYMLLPLVFIPGAMQKFSPVAYDFVFPI
                     TAIGCSAHYCSKHGLDFLFALIAPIIYLPSMLIYNGGFSSSTLSTNLILLVVYLVAGIF
                     GLFLGDLAFGDKRRQKEKAEQEEAEEMLLEAKRREKEELENMTSSSKKSEKKAPYRQER
                     KPARRPSPAPQKTETADDDDFDYDKYLSGIDRKQDPNESEIDDILNEYGH"
     CDS             complement(12475..13383)
                     /locus_tag="ctg6_9"
                     /transl_table=11
                     /translation="MKNIIKKITAIAMCGVLTVGSVLMTGAVSEYEDRKDFEVTGTTQK
                     ISNNQLFVTTTGYTENTAKNFGAMFISTDYQKYSVMFKDCIDAPKFVNLPKNQEFTRHM
                     ITANNRYFGNTGMKFNYDSTGGEYVKMRIKLSDYFPDVFNDDGTMTGKLSDGTYKNFDF
                     TYEDFGTDSSGKPCYATSGAYFVSGGAVTSFVPDKNGYAEFYISRQLGEDTGLMAYKYC
                     RLKNGAECKTTIGGKLNCLTCGDVYPDGNITVVDATSVQKYVAGIVEFGKTQLFNSDVN
                     HDGEISVVDATLIQKYIVGLI"
ORIGIN
        1 tcatttttat ataataaaaa ctgtgtatat gttcgatttg tttttgcaaa caaaccgatt
       61 ggcgaacacg gttcgccgct actgaattgt aatatttata aaaattgtat ataacaaaac
      121 ttttctgcca ttacttactg gcggataata tccgccccta cagacgatac atagctttca
      181 ttacatcaaa aaatatttgt taaacataaa atttcatcaa ggcgggcgtc caatgaacgc
      241 ccctactgat aaactttcat ctaaacaaaa tctcccgaac acggcaaatg ccatattcgg
      301 gagaattttt tatttattca catattcact ttgtacaagc tttagccaaa attattcggc
      361 atcgggaagg cttgcaagct tttcaaggtg agcatactta tcagcagcaa ccttttcagc
      421 cttttcaaag agtttttctg ctctttcggg gaatgaacga gtgagtgagt tataacgaac
      481 ttcgcccatg atgaagtcac gatatgatgc agaaggagct ttaccgtcaa gcatgaacgg
      541 attctttcct tcgtctgcaa gacgaggatc gtaacggaag atgttccagt aacctgcctc
      601 aacagccttt ttctcctcaa gctgagcaat gcccatgccg cccttgatac cgtggttgat
      661 acacggagca tagcagatta cgagtgacgg accgttgtag ctttcagcct caaccatagc
      721 cttgagaacc tgattgttgt cagcacccat agcgcactgt gcaacataaa catagccgta
      781 gctcattgca atagcggcga ggtctttctt cttaacagcc ttacctgcgg cggcaaactg
      841 tgcaaccgaa cctacaggag tagcctttga agcctgaccg cctgtgttag aataaacctc
      901 agtatcgaat acaaggatat taacattttc gcctgatgcg attacatggt caagaccgcc
      961 gaaaccgata tcgtaagccc aaccgtcacc gccgaagatc cacattgact tcttagcaag
     1021 ttcgtccttg tcaacgagtg ttttcttaac aagttcgcca acctttgcat cctctgtgtt
     1081 cttttcgagt tcagcgataa gagcgtctgt tgcaggacgg cttgaagttg aatctgttac
     1141 tgtgtcgaga tagttctggc aagctgtctt gaggtcagcg ctgtctgtat ccttctgaat
     1201 accctcaaca tactcgataa gtctgttgcg gatagccttc tgaccgagag ccataccaag
     1261 accgaactct gcgttatctt caaagagtga gttctgccaa gcaggaccgt aacccttctt
     1321 attctttgta taaggtgttg caggagcaga tgcaccccaa attgatgaac aacctgtcgc
     1381 gttagcgata aacattctgt caccgaaaag ctgtgtaaca agctttgcat acggtgtttc
     1441 accgcagcct gcgcaagcgc ctgagaattc aagcaacggc tgtttgaact gactgccctt
     1501 aactgtagtg aacttgaact tctcgtgaac ttcaggctta tcttcaagtg tgagagcgta
     1561 gtcaaatact gcctgcttag gacgctgtga gtcgattggc tgcattgtga gagccttagc
     1621 gcccttctta cccggacaaa cctgagcaca agcgccgcaa ccagtacagt cgagtgttga
     1681 aactgtcatt acaaagttga ggtccttgag tcccatcatc gggaggctct ttgtaccctc
     1741 gggagctttt gcaagctcat cggctgtcat ggcaacagga cggattacag cgtgaggaca
     1801 tacgattgca catctgttac actgaataca gttttcagga ttccattcgg gaacatcaac
     1861 tgcgatacct ctcttttcat aagcggcaga accgttagga gcagtaccgt caacatgatc
     1921 cataaatgtt gaaacaggga gcttgttacc cttatatgca tttacaggct tgaggatttc
     1981 gtttacatac tcaacgagag caccgttacc ctctgccttg tcggcagttg aattatcaac
     2041 agcgttagcc caatcagcag gaatttcaac cttcttgagg tcttccatac cacggtcgat
     2101 agcggcgtag ttcatatcta cgatagcctg acctttcttc atgtatgact tcttagcggc
     2161 agccttcata agctccttag ccttgtcggc aggaatgata tctgcaatct tgaagaatgc
     2221 tgactgaaga actgtgttga tacgaccgcc gagaccgatt tccttaccga tcttgatacc
     2281 gtcaattgtg tagaagttga tgtgtctttc agcgagaatc ttcttcatct tacccgggag
     2341 acgctcggaa agctcttctg tatcccatgg gcagttaaga agaaatgaac cgccttcttt
     2401 aaggtcatca acaatatcgt acttgtcaac ataagacgga ttgtgacagg caacaaagtc
     2461 tgcctttgaa atgtagtatg ttgacttaat aggagtttta ccgaaacgaa ggtgagaaac
     2521 tgtaagaccg cccgacttct ttgagtcata tgcaaagtag ccctgagcgt acatatcggt
     2581 gttatcgccg ataatcttga ttgagttctt gttagcaccg acagtaccgt cagcaccaag
     2641 accccagaac ttacagctgt gtgtaccctt cggagttgta tcgggatttt caacaatcgg
     2701 aagtgagagg tttgtaacat catcaacgat gccgattgta aatcttctct taggtgtttc
     2761 gctttcagcg tttctgtaaa cagcgatgat gtcgcctggt gttgtatcct ttgaaccaag
     2821 accgtatctg cctgtgtaaa cctttacacc tgcaaagtcc gaaccgttga tagcggcgag
     2881 aacatcaaga taaagaggtt cgccgattga accgggttcc tttgttctgt caagaacaga
     2941 gattgtctta acagtcttag gaagctctct gagcatatag tcggcaacga aaggtctgta
     3001 aaggtgaact ttaagaagac cgaccttttc gcctgcggca ttgaggtagt caacaacttc
     3061 ttccgtacag tcacagacag aacccatagc aacgataaca tgctctgcat cctctgcacc
     3121 gtagtagttg aatggcttgt agtcagtgcc gattttagca ttaaccttgt ccatgtactt
     3181 aacaacaact tcgggaactg cgtcataata cttgttacaa gcttctcttg cctggaagaa
     3241 gatatcgtcg ttctgagcag tacctcttgt tacaggatgc tcagggttaa gagcacgacg
     3301 acggaaagcc tcaactgcat cccagttaag catatcggcg aggtctgcgt aatcccactc
     3361 ctcaatcttc tgaatttcgt gagaagttct gaaaccgtca aagaaatgaa ggaaaggaac
     3421 tctgccttca atagctgcaa ggtgagcaac agcggcaagg tccatacatt cctgaggatt
     3481 gtttgaacaa agcattgcat aacctgtctg acggcaagcg tagatatctg agtggtcacc
     3541 aaaaatagaa agtgcgtggc ttgtgagcgc acgggctgat acatgaataa cgcccggaag
     3601 gagctcgcct gccatcttgt acatattcgg aatcataagg agcaggccct gtgatgctgt
     3661 gtaagttgtg gtcaaagcac ctgctgcgag tgagccgtga acagcacctg atgcgccgcc
     3721 ctccgactgc atttccgtta cctgaacctg tctgccgaaa aggttcttgg caccctgtgc
     3781 cgagaacttg tcggtaaggt cagccattac ggaagaaggt gtaataggat agatagccgc
     3841 aacatcggta aacgcataag aaacatgagc tactgcgctg ttaccatcca tagttttcat
     3901 ttttcttgcc aatggaatcg tcctcctttt taatcaaagc ggcaaaggaa atgatgccgc
     3961 ataaattttc gatacccgtt aattacgcac cgtaaatcaa caagcggtac ggatactttg
     4021 tatcatctta aattttatca cttaaacacc gatttgtaaa gtgttttaca caagaaattc
     4081 aaagcaggat atatattttt gtttcgtttt ttacaaaaaa gtttttatat ttacttgttc
     4141 ctgtcaaaat actttgttgt tgatttttta aaaatcaata acaaaggttt tggttatttg
     4201 tacgaacggt tgcaatacta cgctcgggca taatatgttt tttacattac aaactgtctg
     4261 cacgaattgg gaacggcggc tcgccgtaat tttcaattta caaatgcttt atcgcttcgc
     4321 ttaaatccgt acacaaaaaa tctatcatcg gtttaatttc gtctgtcggc tctgacaaat
     4381 cgggtaccat aaccgtggtc atacctgcgg catgtgcaga ttttatgccg ttaatgctgt
     4441 cctcaaacgc aacgcagtcc actggctcaa gtccgattat aaccgaattg agaaaggtca
     4501 aaagtgtata tgacgagccg actgccgcaa gggcattgtc gcccgcatat tttccgacca
     4561 tccatgtatc ggcaaggttg taaaactgct gaaacacatt gcagagcata agcggtactg
     4621 caaaagaccg caggccgcct gttatactgc ctgtggtcaa atctctgttt ttatttagtt
     4681 ttaccacaaa atcattccgt tgcaaccgca gattctgcgg tcatattttt ttgttaaatt
     4741 cacttccgca tttcggacag cgaacagtat gattgccttt tttgttgcga acacgaagct
     4801 gcgccttgca cacgggacac ttgatataac ggtagtcctt gcggtcacga attttcttga
     4861 aggtcagttt gaaccaacct gttaccgcat tgtaaatcgg aagaaatttt ctgttttcgg
     4921 cacttcttgc aacaatgttg cgtgagaaca tacgaaaaca gataagcacg ataatcaaga
     4981 gcattattcc gtcaatgatg tatcttgcaa cacggttcca cacaaaaata ttcacgaacc
     5041 acagtatgag caacagcacc cagagtgcat tgttgagctt atccgtgccg tatctgccct
     5101 gcataaaatt ggcgaatctg ttaaataatc ctcgcataaa gttcatcctt tccgcaaaaa
     5161 gcggtaatta caaaaatcat ccttccacca ttttatcaca ggcagggcgt acattcaata
     5221 aacatttgac gatatatgtc actaaatcag ccgagaacaa gctttgccgt gtcaacgctt
     5281 tcttttgcgt cacggcagta gtagtcagcg ccgattttca tagcgtagtc ctttgtaaga
     5341 accgcaccgc cgacaaatat tgtacatttg cttgagccgt cgggattctg aagttcctta
     5401 cattctctta caagccttat tgtatcttcc atgctcttga gggttgttgt cataagagcc
     5461 gaaagtccta tcattgtaat attctgttca acggcagtat caacaataag ctgaggatca
     5521 acatcacgac cgaggtcaac aactgtgtag ccgtagttat caagaagaac ctttacaatg
     5581 ttcttgccga tatcgtgaat gtcacccttt acggttgcca caataatttt acccttgctt
     5641 acgggagttc cgcttgtctt tgtaaggtgc tttttaatta catcaaagca ctcctgagct
     5701 gtgtttgcac tttggataag ctgtggaagg aagattttat tcttttcaaa atcttcaccc
     5761 actctgtcaa gtgcagggat aagcatttcg tttacaacct gcattgcatc ggttgtttca
     5821 agaagctttg cggttgcggc tgcaccttcg tttttaagtc cgttataaac agccgcaaaa
     5881 atatcaacat tgctgtctgc ctttttaacg ggagcagcag gaacagcatc gttatatgcg
     5941 ttgataaatt caagcgagtt cttgtcaatg ccgttaagca cacggaatgc tcttacagcg
     6001 cctgtcatcg actcaacatt tgggttgata atcggcaaat caagtccctg ttccatagcc
     6061 attgtaagga aagttctgtt gacaagctca cggttcggaa gtccgaacga aatgtttgat
     6121 acaccgagac aggttttaca gccaagttcc gtttttactc tgtgcaaggc ctcaagagtc
     6181 tgacggcaag cagcctgttc tgcggaaacc gtaagagtaa gacagtcgat atatacatct
     6241 tttctgtcaa tgccgacagc ctcggctctt tcaacaattc gttttgcaat ctcaaatctg
     6301 ccctcggcgg ttttcgggat accgttttcg tcaagtgcaa gtccgacaac agacgcaccg
     6361 tactttttga ctagaggaag aaccgttgca aggctctgtt cctcaccgtt tacggagttc
     6421 agaatcggtt tgccgttgta gtagcggagt cctgcctcaa taacctcggg ctttgtggag
     6481 tcaatctgga gcggaacatc acacacactc tgaatagcct tgagaacacg caccatcatc
     6541 tttttttcgt caatttcggg atggcctaca ttgacatcaa gaatttccgc accgccctga
     6601 acctgactga gagcctgagt gaggatatag tcaatattat tttcaacaag cgcctgctta
     6661 aacagctttt tacctgtggg gttaattctt tcgccgataa ttctcggacc gttgatttcg
     6721 acaaccgtcg ttgaactgca aacggttgtg tcaacgcttt ttgtctgagg ctgatattct
     6781 ctgtcggcaa cctccgactt aatttttgca atataatcgg gattcgttcc gcagcatccg
     6841 ccgataacct taacaccgta tttgaggagt gaacaaacgc actcggcaaa tttatcgggc
     6901 ataatgttgt actcgttgct gttaggatcg ggcaaacctg cgttagcctt gattacaagg
     6961 ggaagatttg tgtatttcga catctcggaa acaacgggtt caagctcatc cggaccgagt
     7021 gaacagttga caccgagagc gtcaacaccg agtcccgtaa gagtgacagc cgcacaggca
     7081 ggggatacac ccgtaaatgt tcgtccgttt ctctcaaagg tcattgttgt gaggataggc
     7141 ttgtcgcagt tttcctttgc ggcaaggact gcggctttaa gctcataaag gtcggtcatt
     7201 gtttcaaaaa ctatgacatc ggcatcttta ccggcaagaa tctgctgttt gtaatactca
     7261 taagcctcgt caaatttcat tgaaccggca ggttcaagca actgacctat cggaccgata
     7321 tcaagggcaa cgagggcatc tgtaccctca acggcttttc ttgcaatctt aacaccggcg
     7381 ccgatgattt cttcaacgct gtaaccgctg tcctgaagct tgtaggcatt tgcaccgaag
     7441 gtgtttgcgt acacaatgtc agatccggca tcaatatacc tcctgtgaaa gctctcgata
     7501 agctcggggt gagtaatgtt cagcacctca ggcacatgat cgtactttac accgcttttc
     7561 tgaatgagag ttcctgttgc accgtcaagc agaataaaat tcttttggtt gagatattca
     7621 ctaaagtttg aaaaattctt aaacaccaca atgttcccca tttcttctga agcgacattt
     7681 gcctttcata ctgcaaattg cacaccctcg ttttcttcgt tcaatcggat tgtctgaaat
     7741 tccgagaacc gccgtaaccg actttgacgg cacaagcaga cagctgtcgc ctgttgtaag
     7801 acctattttt ctcggagcgt caagtattct cagatactcc ttctgcatct caataggata
     7861 gtccccatag ccggggctga aacggaaggt catatacttt ccgctgtatt tttcggcaag
     7921 gatttcgtca accttttgac acacctgttc aacggcaacg cttgcaaagc tgtcaagcac
     7981 aaccgccctt gccatatcgg aaatctgact tatacggata agcttgtcaa tttccgaacc
     8041 gattgtagca cacatcataa cggctgtgtg acagccctca aggtgctttt ttatatcatt
     8101 gccgagtaaa atatcgtcaa acggagcttt gcgttcaaca tagagaaatc tcggctctgc
     8161 tgttttcaat atttcttttt cgcattcatc catcagcaca tccatgcggt aattaaggct
     8221 gattcctgca ccgccgaggt agcgtatagc ctctttgcgg tttaatctgt caagcgttat
     8281 cataaaagac ttgacaccgc ctccgtaatt tttcttgcaa catacgggtt gttcattgta
     8341 tagaggtgga tgccgtcaac accgtgtgcg ataaggtcaa caatctggtc aaccgcatat
     8401 gcaatgcctg cgtcacgcaa agcctcgggc cttgtatcat acttctgcat aatctttgca
     8461 aattttgcag gaaggcttgc accgcacatt gaaaccattc tttcaatctg acttttgctt
     8521 gttacaggca taatacctgc ctcaatcgga acattcacgc ctgcaatctt cgctctttca
     8581 agaaaacgat agtaagcgga gttgtcaaag aaaagctgtg aaataaggtg gcttgcaccc
     8641 gactcaacct ttttgcgaag gttgtgaatg tcctcaacct catcggttgc ctcgctgtga
     8701 acctcgggat aacaagcgcc ggcaatgtca aaatcaccct gtgacgcaat atatctgcac
     8761 aaatcgcttg cataagtaaa atccttctgc ggttcaacac cttcaaccct gtcaccacgg
     8821 agtgcaagaa tattctcaat gccgttctct ttaaaaagcg caaggttgcg gtcaatatca
     8881 gcctttgtgc tgttaatgca ggtgaggtgt gccacggatt caactccgaa atctctcttg
     8941 atttttgttg cgatttcgca ggtacggctc tttgaaccgc tgccgcctgc gctgtatgtt
     9001 acgctgatga agtcaggctt taaagccgaa atttcttcaa gcttgccgta aaccgattca
     9061 atcggagagg tctttttagg cggaaatact tcaaaagaaa aaactgtttt tccgccgtta
     9121 aataaattgc ttattttcat atataaacac ctcggtaatg gttttgttaa acttgattaa
     9181 ttatagcata aataattttt gcatacaata ctgttttggt gggttttgtc gtttaagact
     9241 atcatttttt gggaggtttg gatataagca aaaattatat caaagagttt tataataatt
     9301 ataattttgt taacaaacca aattcaccat tatatctgta tatctgtaga ggagaaccgt
     9361 gttctccact acagagtata aattcacttt cataataaag caaaaattgc atcaatgccg
     9421 tattctggca tctgatgcaa ttcctttatc cgagtatctt ctcgaataga ttgcggtggc
     9481 acaccgccga cctcaatttt caattttcca ttttcaactt tcaattttaa aaaaatcaca
     9541 aatgcaaaat caactttgca acgccgaaat agataagcaa tgaaagcgag tcgcagactg
     9601 ttgaaatgag cggattcgcc ataacggcag ggtcaaagcc gaccttgctt gccaaaagag
     9661 gcagactgct gccgacaagc tttgccataa taattgtacc gacaagcgta agcgaaatta
     9721 caagggcaat cataaatgcg ttttcctgac cgttgagatc aaacaaaagc agttttacaa
     9781 agtttgccgc cgcaagcgta ataccgcaaa gaattgacac cctgaattct ttccacagca
     9841 caaggaaaat gctcctgaaa tgaatttcac cgagcgacaa cgcacggatt acggaaaccg
     9901 acgcctgaga acctgcgtta ccgcccgaac ccgtaatcat cgggataaac gatgagagaa
     9961 tcaaaacatt tgcaagcaca gcctcaaatg atgagataat cgcacttgta aaggttgccg
    10021 aaagcatgag tataagcagc cacggcgctc tctttttgta cagaccgaaa acgcttgttt
    10081 tcatatacgg tttgtcagat ggcaatacgg ctgccatctt ttcgatatcc tcggtagcct
    10141 cttcctgaat aacatcaata gcgtcgtcaa ttgttacgat accgacaagt cggttttcgt
    10201 tatcaacaac aggaagagca aggaagttat agtttgagaa catctgggca acctgctcct
    10261 gatcggcaag agtagttacc gagataacat tttcctccat aatcgacttt acaagctcgt
    10321 catcttcggc aagcaaaagg tcttttacag tggtaatacc gataagcttg ttgttggcat
    10381 cggtcacata gcaggtgtag attgtttcct tgtcaacacc tgttcttctg attcttttaa
    10441 tagccatttc agccgtcata tcgggacgaa gcacaataaa ctcggttgtc ataatcgagc
    10501 ctgcgctgtc ctcgggatat ttcaaaagct cgttaatctg ctttctcata tccttgtcgg
    10561 cctgtcttaa aatacgcttt acaacattgg caggcatttc ctcaataagg tcaacggcgt
    10621 catcgacaaa taactcatcg acaacctctt tcagttcgct gtcgctgaag ccgtggataa
    10681 ggaattcctg agtttcgtca tccatttcga caaaggtttc cgccgcaagc tcctttggca
    10741 gaatacgaaa cagaatcggc attttttcat cctgtagatt ttcaaaaacc gccgcaatgt
    10801 caaacggttt catcgtaatc aaaatgtcac gcaaagtgct gaactttttg tcatcaagca
    10861 acactttgat agtttcggta agggttacgt taacctgttc catcatcttt tcctcctttt
    10921 taattcaatt ggaagtaaag acggtgtcac cctgagtatt aaattaaatc aattcaaatt
    10981 aaaataaaaa tacaaagcaa aatcaataaa acaaaatgaa cgcacaagcg cacattctgt
    11041 tgcaacttcg cccgggtaca gcgcctttat taccgtctgc gtccattaag ttttcacctc
    11101 attcgcattt aaattcgggc aaaagcccgt acatatttat tttattcttt tttatgtccg
    11161 atgtcaacgg atttatccgc taaaaatcca ctttgcaaac attttacatt atcctctgta
    11221 acagcttggt aactcggtat aatatttctt gcttttttaa gtgtatcaat gtataataaa
    11281 tatgcatgat ttaaaataaa atttcaaaga ttggagatta accgttatga cagatatggt
    11341 taaaaaatat gttccctatg cggtaataat tttgcttgtt tatatgctgt tgccgcttgt
    11401 gtttattccg ggcgcaatgc aaaagttttc acccgttgca tatgactttg tgttcccgat
    11461 tacagcaatc ggctgttcgg cacactactg ctcaaaacac ggacttgact ttctctttgc
    11521 actcattgcg ccgattattt atcttccgag tatgctcatc tacaacggtg gattttcttc
    11581 aagcacactt tcaacaaacc ttattctcct cgtagtttat cttgttgccg gaattttcgg
    11641 acttttcctc ggcgaccttg ctttcggtga caagcgccgt cagaaagaaa aggcagaaca
    11701 ggaagaagca gaggaaatgc tccttgaggc aaagcgccgt gaaaaggaag agcttgagaa
    11761 catgacttca tcaagcaaaa agtccgaaaa aaaagcacct tacagacagg aacgcaagcc
    11821 tgcacgcaga ccgtcgcctg caccgcagaa aaccgaaaca gcagatgacg atgattttga
    11881 ttatgacaag tacctttccg gtattgacag aaagcaagat ccgaacgaaa gcgaaattga
    11941 cgatatctta aacgaatacg gacactaacg gcgagccgcc gttcccagtt cgtgcagata
    12001 gtatttataa gggcgaaaat aaaatgcccg agcaaaactt tatagctaaa aatgtaaaat
    12061 taaagtcggg aagacaattt gcgaaatgca aagcattgtc ttcccgactg tttttgttta
    12121 atcatcaggg gtgttcatcg gacacccgtt ttgattaaat tttatgttta aataagatta
    12181 tgtgatgtta tggaagttgt gtatgatttt gtagggaaga accgtattct cccgcacggc
    12241 gagccgccgt tcccgattcg tgtagatagt ttgtaatata aaaaaacata tcatgcccga
    12301 gcgtagcatt gcaatttttc gcacaatccc gtaggggcgt tcattggacg cccgccaagt
    12361 aatgacagaa aatttatgat gaaaataaac tgtataaatg agatacagaa ttgcagttac
    12421 tttgtaacat ttatatcatt taatttacaa tattatttgt accattattt ttgtttaaat
    12481 caacccaacg atatacttct gaatcaaggt tgcgtcaaca acactgattt caccgtcatg
    12541 gtttacatcg ctgttaaaaa gctgagtctt gccgaattct acaatacctg caacatattt
    12601 ctgaacagat gttgcatcta caaccgtaat gtttccgtct ggatatacat caccgcaagt
    12661 caggcagttc aatttgccac caatcgttgt tttacactct gcgccgtttt taagtctgca
    12721 atatttataa gccataaggc ccgtatcctc gccaagctgt cttgaaatat aaaactccgc
    12781 atagccgttc ttatcgggga caaaagatgt taccgcacct ccgctgacaa aatatgcgcc
    12841 cgaggttgca tagcaaggtt tgccgctgct gtctgtaccg aaatcctcat atgtaaagtc
    12901 aaaattcttg tatgtgccat cgctgagttt tccggtcatt gtgccatcat cattaaagac
    12961 atcaggaaaa tagtcggaga gtttaatcct catcttaaca tattctccgc ctgttgaatc
    13021 ataattgaat ttcatacccg tattaccaaa ataacgatta ttcgctgtta tcatatggcg
    13081 agtaaattcc tgatttttcg ggagatttac aaacttcggt gcatcaatac agtccttaaa
    13141 catcacgctg tacttttgat aatccgttga tatgaacatt gccccgaaat tctttgccgt
    13201 attttcggta tatcccgttg ttgtaacaaa aagctgattg tttgagattt tctgcgttgt
    13261 acctgtaact tcaaagtcct tgcgatcttc atactcgctt accgcacctg tcataagaac
    13321 cgaaccgacg gtaagcacac cgcacattgc gattgcagtt atttttttaa ttatattttt
    13381 cattgttttt cctctttcta tcagtagggg cgctcattgt gtcaagtgca acatggacgc
    13441 ccgatttgat tgaattttat gttttcgcaa aatcagttga tgttatggaa gttgtgcgta
    13501 attggcgaca tatatataat tatataatct gtcttatcaa aaagattgta ccattacttc
    13561 gtcagtttgc ttttatatga aattttcatt taactcaacc ctacaatata cttctgaatc
    13621 aaggttgcgt caacaacact gatttcgccg tcatcgttta catcactgtt aaaaagctga
    13681 agcttgtcaa agtcctcaat acctgcaaca tatttttgaa caagagttgc atcagtaaca
    13741 gaaatgtatc cgcttaaatc cgtatcaccg caagttaaac cgaccagagt atctccgatt
    13801 attccgtaat cgcaatgagc tccgtcttta agtctgcaat agcggtatga cattactttt
    13861 gtatctacgc caagctgtct tgaaacatat atttcagcat agccgtcctt at
//
