LOCUS       c00003_gnlPro..        16158 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LAIFGBKF_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:25:32
            Original ID  :: gnl|Prokka|LAIFGBKF_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16158
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16158
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3165:6158]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3166..6158
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16158
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16158
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             142..513
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="MISAPTDKQQLSYIKNSREDDVLHFANRLPDIHFTFSIFHFQFKI
                     SVRASLFSLLRNYLLKLTAAVYCTVTVIVTLDVLLSTSVTEYVTLYLPFRVVTTLPKTS
                     IFDVMSLPQVSTAVTPARA"
     CDS             complement(339..974)
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MICSTGLDNSTITGDYTIGIKSEWLFLVGDVFGRYISGISGDYLF
                     HSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSIYDDAENA
                     GPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPIISGANDYTIKSGGEFYALAGVTAV
                     DTCGNDITSNIEVFGNVVTTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             1201..1434
                     /locus_tag="ctg3_3"
                     /transl_table=11
                     /translation="MAEIRAVPSLRASTLPPSSTVTILLSELVHLVTDFAFSDDSSISF
                     DSPTFNVSESTLLGNVIFSVTAVSGVCGFGEF"
     CDS             1691..2227
                     /locus_tag="ctg3_4"
                     /transl_table=11
                     /translation="MVIIMAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSP
                     TEFIPGAKYFQGTRSPNEKERELYGYSQAWLHHKGRNRHHYEYWNDYNPKTKQIENVEM
                     PVKYVIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRD
                     EGEEKTFAYIRSMKK"
     CDS             2408..2899
                     /locus_tag="ctg3_5"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYENIDTLPYRILVEADFLVNLYEDDSSRSAAEQAYDKLFRTKTGKNLLKIMFLIP
                     "
     CDS             3166..5403
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_6"
                     /sec_met_domain="Gly_radical (E-value: 4.4e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6.6e-272, bitscore:
                     894.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQKNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGIAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             5403..6158
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_7"
                     /sec_met_domain="Radical_SAM (E-value: 2.2e-30, bitscore:
                     97.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLYRLADFIRSLRNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGINPPTKERVKNAEMILNGEKTRD"
     CDS             6704..6922
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPQAAVTAEELAEEE"
     CDS             7497..9362
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MKKIQKKLSVVLAVMMVLCMFTALPFSASAAETSEETSAGNKINV
                     TSNVTDPVSYDYNAQTEQVVVTYLLKADHMIVDTQSSLTYDSKVLKLASTTTTNTKNKV
                     FPVFQSSIVWNPSLTNQVLFNCSSLDLFNFKSENVYCTFTFDVVGSGDTTVNLSVDYLT
                     GTEADTYDELFESEKKDIDYIYNSANKVAGAAFTAKAVLVQGEEPTTAPQPTTATQPTT
                     VTQPTTAPATKPTQPATEPTQPQSGVSVTGDIALPLADDGNGIYTGSTELEAGSYTFKM
                     SVNGVAFGNGSTFTDKTTNATYSSKWKSSTTLKATGGKYTFKFNTAKNTLTIEYLAPSK
                     ASIVGDINLDLQATKDANVYSASVKLNKGNYEFRVMNQDVRYCCGYTYKDFTVGSQFSS
                     KWSSASTLAASGGTYTFSYDIDTNKLTISYLPSGAEVSVVGNFTLALAKTDKENVYSGT
                     KTLKAGKYQIKMNNYGKLCGTSAVVKDATPGLVFSPKWSKYTTFVATGGTYTFTYNTAT
                     NKLVVTADKGDIPVKVTGDINLTLKKSDTNVFTGSVKLKRGDHSFKMNVNGTDFCSGAT
                     IRNATTGTVKYNSKFTSATTLVAIGGTYTFTYNTLTNQLSVKYSK"
     CDS             complement(9903..10484)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_10"
                     /sec_met_domain="Hexapep (E-value: 2.4e-13, bitscore: 40.9,
                     seeds: 216, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLFALRSIFLLPHFFVFKLCEKHDVLCKDLESWRKLCPKKNNC
                     SYTYLFFYMMCHFKEFRNVFYLRLGNIKYFLKIFCKPLDSLYLTSKNMGPGLFIQHGFS
                     TIVGVESMGSNCWINQQVTVGHTEKGRPKIGNNVKIMTGAKVLGNVTIGDNVIIGAGAI
                     IVKDVPSDCVVVGSRAYIVKRNGKKVREEL"
     CDS             complement(10538..11668)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_11"
                     /sec_met_domain="Fer4_7 (E-value: 1.8e-09, bitscore: 29.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIFPSKSECCGCSACKQICPKGAIAMKPDSEGFLYPQIDVSLCI
                     ECGACQKICAFQNGYEKNHSKTAYAIKHKDFNTRFTSRSGAAFVALSDYILNKKGSVYG
                     AAFQDDFSVSHIRATDRYVRDKFKGSKYVQSDMKDTFKSVKNDLNNDMYVMFSGTACQV
                     AGLKRYLGKCDTSKLYTCDIACHGVPSPIIWKEYLKHCEKKFCGKVTKADFRDKTIGWN
                     THKEAIWIDDNKHILNGYTYLFYEDDIERPSCYNCKYSNLDRPADLTLADFWGIDRVVE
                     NFNDNKGVSLLLVNSEKGSRILNKVIGNIHCVECDLNASIKSNPNLSCPTAKPDSREDF
                     WNFYYKNGFEKTFKKYYNKIIIKKIKRRIMNKDEVL"
     CDS             complement(11671..12756)
                     /locus_tag="ctg3_12"
                     /transl_table=11
                     /translation="MKKIGIITFHRAKNYGAVLQAYALQHTLKQLGSDCEIVDYKCENI
                     DNGYKPFQFSKTDPIKSILKSIVMYRKRAKKIEQFSSFYNNYLKISNKTYSNSDISECK
                     NLYDAFISGSDQVWGPGKEGINPDSIYFLSFADDNQKYSYAASFGVADISDVKAMQLRP
                     LLKNFQSFSVREKSALNIVKKITGKNGVCHIDPTLLLNKDEWQKISVKKIDKPYILVFN
                     VKPVKSLIDFAEKLSKKTGIPVVYITDNPQKKRKNFTYVSAPTVEEFLGYFANADYTVT
                     NSFHGTAFSVIFHKNMFVEYETAKGFNHRAKNLLQTIGINREIKDGEAVTTDIDWNKVD
                     NILQAERKLSLDYLKDIIKGE"
     CDS             complement(12772..13674)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_13"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.7e-31,
                     bitscore: 98.8, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNVEITVFTPSYNRAKTLPRVFECLKKQTYKSFEWIIIDDGSED
                     NTKDVVDGFLKEDNFFDIIYVYQKNQGKHIATNNAVKMCSGNFFITLDSDDTCTNDALE
                     TFVNEWNKIPKQEQKKYYGISCRTYDKDGKINGTQMNVPYIDSNDLDLRFKLNITGELW
                     GMIRTDIMREFPFPAVEGYHFYPENVIWHNVGRKYICRYLSTALRYYIQDQENAVTNVN
                     RKKASKEKFVMHLHYINDCWDYRKYNRKRYLEHIVAITRDGLANGYKLSEILTMLKTKP
                     RRLLVLLTSPIGYLLYKHS"
     CDS             complement(13688..15217)
                     /locus_tag="ctg3_14"
                     /transl_table=11
                     /translation="MPKSAGKQMSINIIASIVSFAVTVGINFFLTPYLVKEVGSDAYGF
                     IGLANNFVQYATIVTTALNSISGRFISIAYHKGDVEKSSKIFSSVLVADLFLAAVMLIL
                     SSIFVCFLDTVLKIPSNLVSGVKITFAFAFLTFVVSTVTAIFTTAAFVKNRIDINSIRD
                     IISNLIKVALIVLLFAIFPAQLYFVTLASFGSGIFLLLANITVKKKVLPEVKADIRKFD
                     IKIVKTLLASGIWLSLAQLCQVLLSGLDLLICNLTLGTALMGLLSIAKTVPNSIGNLTV
                     ILGSVFTPHYTILYAKKKIPELIIEAKFSTKIVSFILSTPIAGFIAFGRQFYILWQPTK
                     SPEEITMIQFMSVLTCITFLCSSQTQSLMMINTVCNKLRLPVFVNLTVGIVSVIVAIAA
                     CNLTDYGVYFVAGTSSVLMGLRALIFTPAYSAYILKQKLSIFFPTVIRDCVGFIIILVL
                     FSIISNLITVTGWSSFIFICAICGILAYTLSLPLLFNKAELCKLKNKLTKK"
ORIGIN
        1 aaactgtata ctatgtcttt gcactgttgt atactatgtt actacactgc acacacggtt
       61 catccataca ttattacagt tgctttgcag catttataaa atttgtatta atatgtagtc
      121 tgtaccgttg cttgcgggcg aatgatatcc gccccaacag ataaacaaca actttcatat
      181 ataaaaaaca gtcgggaaga cgatgttttg cattttgcaa accgtcttcc cgacattcat
      241 tttacatttt caattttcca ttttcaattt aaaatctccg ttcgggcatc tttattttcg
      301 cttttgcgga actatcttct taaattgact gcggcggttt actgcaccgt taccgtaatc
      361 gttacgcttg atgttctttt aagcacatcg gtgactgaat atgttacctt gtacttgcct
      421 tttcgggtgg ttactacatt gccgaaaact tcgatattcg atgttatgtc gttgccgcag
      481 gtgtcaacgg ctgttactcc tgcaagggcg taaaattcgc cgccgctttt gattgtgtaa
      541 tcgtttgcac cgctgattat tggtgttgct tttgcatatg ggcatttttt attgctgtct
      601 gtcggatccc atttgttggt gaaatcggtg attttgattg catccggttt tccgagaggg
      661 cctgcatttt ctgcgtcgtc atatatgctt acattcgtgc ctgtggggca gttgtcataa
      721 acccactttg catccgaaac cgcaagtctt acgcatcctt gtgatgcctg ttcgccaagc
      781 ttgttgaact cctcaagctc caaatcttct tcgctcattg agtagtaggg aacggagtgg
      841 aaaagataat cgcccgaaat tccgctgatg tatcttccga aaacatcgcc cacaaggaaa
      901 agccattcgg acttgattcc gattgtgtag tcacccgtga ttgtcgaatt gtcaagacct
      961 gtggagcaaa tcatcgccct tacagggatt gtgtacttgc ccttttcgtc atatgtgtaa
     1021 accgtcacgc agtttgccgt gcggttgacc ttgattgcgt acaggttttt tgccgtgtta
     1081 cgcttattgc tttcaagctt gtcaagattt gccgttatac aggttgagta gctttgctgt
     1141 tttttcgtgg ttgattttgc caccgtaacc tgaaattccg actttgattt gtcttttgaa
     1201 atggcagaaa tcagagccgt accctctttg agagcgtcaa cccttccgcc gtcatcaacg
     1261 gtaacaattt tactgtccga gcttgtccat ttggtaacgg attttgcttt ttcggatgac
     1321 agttcaataa gctttgattc gccgactttt aatgtgagcg aatcgacctt gctcggaaat
     1381 gtcatatttt cggttactgc cgtatcgggc gtctgcggtt ttggagaatt ttgagaatca
     1441 tttccgaaaa ttcccgtcag accgcataat atgcaggttg caatgaggac aacacaaagt
     1501 aaaagaatga aaattttctt tttcatagat tacctatcct tatagaattt aacattaaat
     1561 ggttacaaaa ttttaacctt tgtatattat aacttttttt cgacaatctt gcaagtgcta
     1621 ttttaaatcg gcgagaaatg tggtaaaatg tcagtcggag aatgttttgt attttccaaa
     1681 ctaacaattt atggtgataa ttatggcaca tccgattaaa catttcagaa caataacccg
     1741 tcacaggcac aaggtaattg ccaactgtgc aagggcagga attctcagac agggattaat
     1801 acacgatttg tcaaagtatt cgcctacaga atttattccg ggtgcaaagt attttcaggg
     1861 cacgagaagt cccaatgaaa aggaaagaga gctgtacggc tattcacagg cgtggctgca
     1921 tcacaagggc agaaaccgtc accattacga atactggaac gattacaacc caaagacaaa
     1981 gcagattgaa aatgttgaaa tgcctgtaaa atatgttatc gaaatgttct gcgaccgagt
     2041 tgccgcaagc aagatctaca acggcaaaaa ttacacggac ggcgctccgt ttacatattt
     2101 ttgcagaatc agaggcaaac accgtatgca ccccaacacc gaggctttgc ttgaaaaatt
     2161 attggttatg ctgagagatg agggtgaaga aaagaccttt gcatatataa gaagtatgaa
     2221 aaagtgattg tttgtgcgaa tcctcccgtc tgaaatatag tcgcaatgcg ttgtacataa
     2281 atgtactgcc ttttgctccc tttatccgcc acaggcggcg gtcgcaaggc tacccctaca
     2341 gaattgcaca aacaaaaaaa ctgtctacac gaatagggaa cggcggctcg ccgtaaggag
     2401 tgataatatg aaaaccgaca gggttataac tgctatgatt gaatattttg gaagtgacaa
     2461 gaaaagaatt caccattttc tcaaggttta ttcattcgca aagacaatcg gtgaaagtga
     2521 aaatcttttg cccgacgatc aggagcttct tgaaatctcc gcaatcgttc acgacatcgg
     2581 cataaaggtg agcgaagaaa agtacaattc gtccgccgga aagtatcagg aacttgaagg
     2641 tcctcacgag gctgaaaagt tgcttgctgc tctcggctac gaaaaaacat ttattgacaa
     2701 agtttgttac cttgtgggac accatcacac ctatgaaaat attgatactt tgccgtaccg
     2761 aattttggta gaggcagact tccttgtgaa cctttacgag gacgattcaa gccgcagtgc
     2821 agcagagcag gcatatgaca aactattccg cacaaaaacg ggaaaaaatc tgctgaaaat
     2881 aatgttcctc ataccctaaa attgtactca tttaccatag tattttgagt gtgaaaaagt
     2941 ggtgtaaaaa gtatcccaaa atgcttgaca acgcccttaa aaagtgttat tttaatggtg
     3001 ttggttatat gattataaaa gtgaataaat gacagaatac aaggatgtat gacgattttt
     3061 tcaaggagct gaccttaccg ggcgtctgct tggaattgag tcggcatttt tttgtgtcat
     3121 atacaaaatt cagtattaat tatcattatc ggaggtttta cagtaatgag agaagaatgg
     3181 acaaattttg caggtggcaa atgggagtcc gacattgatg tcagagactt cattcagaaa
     3241 aactacacac cttatgacgg cgaccagtct ttccttgaag gtcctacaga agctacagac
     3301 aagctctggg gcgagctcaa ggaactccag aaggaagaaa gagccaaggg cggcgttctt
     3361 gatatggaaa ctgaggttgt aagcggcatc acagcttacg gcgctgcata tcttgataaa
     3421 gaccttgaaa aggttgtagg tcttcagaca gacaagcctc tcaagcgtgc atttatgcct
     3481 tacggcggta tcaaaatggc tgagcagtca tgccagatgt atggctacac tccaagccct
     3541 aaactccacg aaatctttac aaaatatcac aagactcaca accagggtgt attcgatatc
     3601 tatactcccg agatgaagct tgcccgtcac aacaagattc ttacaggtct tcccgacaca
     3661 tacggcagag gcagaatcgt cggtgactac agaagagttg ctctttacgg tattgaccgt
     3721 cttatcgaag gcaagaaaga ggactttgca gaaacaaacc gtcagggtat gagaagaggc
     3781 gacttccagc ttcgtgaaga aatcgccgat cagattcgtg ctcttaacga tatgaaggaa
     3841 atggcacttt cttacggctt tgatatttca cagcctgcta agaacgctgc agaggcagtt
     3901 cagtggctct acttcggcta tcttgctgct atcaagactc agaacggcgc tgcaatgagc
     3961 gttggtcgtg tatcaacatt cctcgacatc tacatcgagc gtgaccttga gaacggtaca
     4021 cttacagaat cacaggctca ggaactcgtt gaccactttg ttatgaagtg ccgtatggtt
     4081 aagtttgcaa gaattgagtc ttacaaccag ctcttctcgg gcgaccctgt atgggctaca
     4141 ctcgaagttg caggtcttgg cattgacggc cgttcaatgg ttacaaagaa cgactaccgt
     4201 ttcctccaca cacttgagaa tatgggacct tcacctgagc caaacctcac agttctttat
     4261 tcttcaagac ttcccgagaa cttcaagaag tatgctgctc atatttcagt tacaacaagc
     4321 tcaattcagt acgagaacga tgatgtaatg cgtcctgtat ggggcgatga ttactcaatc
     4381 tgctgctgcg tatccgcaac acagacaggt aaggaaatcc agttcttcgg tgcaagagct
     4441 aaccttgcta agtgccttct ctacgctatc aacggcggta ttgatgaaaa gacaaagatg
     4501 caggttggtc ctgaatatac acctatcaca tcagagtacc ttgattatga cgaagttatc
     4561 aagaagtatg acacaatgat ggattggctt gctcacctct atgtaggcac acttaacatg
     4621 attcactaca tgcatgataa gtactactat gaggcagcag aaatggctct tatcgataca
     4681 gatgtaagaa gaacatttgc aacaggtatt gcaggcttct cacatgttgt tgactcactc
     4741 agcgctatta agtacgctaa ggttaaggtt atccgtgacg aggacggtat tgctgttgac
     4801 tttgaaacag agggcgactt cccaagatac ggtaacaatg acgagagagc agataagatt
     4861 gccgttgatc ttctcaagac attcatggct aagctcaagt attgccacac atacagagat
     4921 tcagagccta caacttctat ccttacaatc acatcaaatg ttgtttacgg taaggctaca
     4981 ggttcacttc ctgacggcag aaaagcaggc gagccgcttt caccgggtgc taacccaagc
     5041 tacggcgcag agcagaacgg tcttcttgct tcacttaact ctgttgctaa gcttccttac
     5101 gagtacgctc ttgacggtat ttcaaatact cagacaatca acccgggtgc tctcggacac
     5161 aacgatgacg agcgtgttga caacctcgtt aatgttatgg acggctactt tgatcagggc
     5221 gcacaccacc tcaatgtaaa tgtattcggt acagaaaaac tcattgacgc tatggagcat
     5281 cctgagaagg aagagtatgc taacttcaca atccgtgtat cgggttatgc tgttaagttc
     5341 atcgacctta caagagagca gcagctggat gttattgcca gaacctgcca cgacagaatg
     5401 taatgtcgga caacgctgtt aaaggctttg tacactcaat agaaactttt ggctctgttg
     5461 acggtccggg cgtgagattt gtgatttttc tgagcggttg cgcaatgcgt tgccagttct
     5521 gccacaatcc cgacacctgg aaacacgatg aaaacaccgt ggaatacacc gccgacgagt
     5581 tgcttaataa agcgcttgca taccgcccct attggaaaaa taagggcggt atcacagtaa
     5641 gcggaggtga gccactttta cagattgact ttttgcttga tttgtttaag aaggctaaaa
     5701 agcagggcgt taatacctgt attgacacaa gcgccaaccc gtttacaacc aaagagccgt
     5761 tctattcaaa gtggaaagag ctaatggaat atacggattt gctgttgctt gatataaagc
     5821 atatcgacaa cgaacagcac aaaatcctta caggacagcc aaacaccaat attcttgaaa
     5881 tggcaagaca gctttccgat atgggcaagc ccgtatggat aagacatgtt cttgtgcctg
     5941 aaagaaatga taaggacgag tatctttaca gacttgccga ctttatccgt tcgctcagga
     6001 atgttgaaag agttgaagtt cttccgtatc acacacttgg tgtgtacaag tggaaggctc
     6061 tcggttatga ctatcctctc gagggcatta atcccccgac aaaagagcgt gttaagaatg
     6121 cggaaatgat tcttaacggc gaaaaaacaa gagattaatt tcttatataa caacggcagt
     6181 accgattttt ttggtactgc cgtttttgtt ttgattttta tttgttattc tgcttttgtt
     6241 gtttcttctt cagcaaaatt gatgaatcaa aggtgtattc aaagattttt gagccgtcct
     6301 tgttgagaaa tcgtcaccgt cggaagaacc gactgctact caggaacaga ctgttcagac
     6361 tgctccgacg ggtgagcctg caactgtcgg tacaacctct gtaaatccga cttcggcaac
     6421 aggcggtgcc gcaacatcgg acagcactcc ttcacagcct gataaaaacg gcagtgttca
     6481 gacaggagtg acagcaacgg ctgttatgat gcttgttgta atttcgggcg gagtgctttt
     6541 tgcccttgca gagcgtaaaa agagaatata acacactgac agccatttgt gcaaagatta
     6601 tcagttgtct attgaaaaat ttgtaaaaat gatataaaat atcaataagt agaaaaatac
     6661 ggtttttccg ctgatttata ttaatactga aagaggtgcc ggaatggata aaaacaaaaa
     6721 attattctac acaatcatcg gtgcaatctc tgcacttgcg gctgccacag cagcatttct
     6781 cgctttaaaa aagcacagat gcgcagaaca gaagcttatt gaggaaattg acgatattgt
     6841 ttccgaaaaa gagcctgagg aggctgcaaa ggaagaaccg caggcagcag ttacagccga
     6901 ggagcttgct gaggaagaat aagcaacaag ttgttgcacc aaattcgggt agcagtattt
     6961 gcatgtgcga aagttaaata cccgagcggt gctttcaatt aagaattgaa agttgaaaac
     7021 agaaaatgat gtcagcggtg tgccaccgca gtctattcaa aaaaacagtt taaaaaagaa
     7081 aatgcatcag ttgcccgaaa aggtctgatg catttttgtt ttgttaggct gttttgtcac
     7141 agccccatcg aaattgctct tgatgcagac ttttttgtta caaaacaatt gttgtaaaaa
     7201 ttaaatacga tagtattatt atcagttatt tctgaactga ggaacatgga ttagacaata
     7261 tccacaataa tcagacaatg aatttgtgta taatagcaaa cttaccgtta atttgcacat
     7321 attttagggc aaaaaatttt cgctaaaaga ataacagatt cattgcccga acaacttaaa
     7381 tgtgctataa tttaaatgtc ctcggaaatt ttgtactgtt aaagtttccg aagctagaag
     7441 tattgccaca aaactgtggc gaacggtaat tttattttat taaaggagca gcaagtatga
     7501 aaaaaattca gaaaaagctt tctgtggttc ttgcggtaat gatggtgctg tgcatgttca
     7561 cagctctgcc tttctcagca agtgctgccg aaacaagcga agaaacaagt gcaggcaaca
     7621 agatcaatgt tacatcaaat gtgacagatc ctgtttcgta tgattacaat gcacagacag
     7681 agcaggttgt tgttacttac cttctcaagg cagatcacat gatcgttgat acacagagca
     7741 gccttacata cgacagtaag gttctcaagc ttgcatcaac aacaacaaca aatacaaaga
     7801 ataaggtttt ccctgtattc cagagcagca tcgtttggaa tccaagcctt acaaatcagg
     7861 ttctcttcaa ctgctcaagc cttgatcttt tcaacttcaa gtcagagaat gtttattgca
     7921 catttacatt tgatgttgta ggcagcggtg acacaacagt aaatctcagt gttgattatc
     7981 ttacaggtac agaggctgac acatatgatg agctcttcga aagcgaaaag aaggacatcg
     8041 attatattta caatagtgct aacaaagtag caggtgctgc atttactgca aaggcagttc
     8101 tcgttcaggg cgaagagcct acaacagctc ctcagccgac aacagcaaca cagcccacaa
     8161 ctgtaacaca gcccacaaca gctcccgcaa caaagccgac tcagcctgca acagagccga
     8221 cacagccaca gagcggagta agtgtaacag gagatatcgc actcccgctt gcagatgacg
     8281 gcaacggcat ttatacaggc tcaactgagc ttgaagcagg ttcatacaca ttcaagatga
     8341 gtgtaaacgg agttgcattc ggtaacggtt caacattcac agataaaaca acaaacgcaa
     8401 catacagttc aaagtggaaa agttctacaa cgcttaaggc aacaggcggt aagtacacat
     8461 ttaagtttaa tactgcaaag aataccctta caattgaata tcttgcacct tcaaaggctt
     8521 caatagtcgg cgatatcaac cttgatcttc aggcaacaaa ggatgcaaat gtttattcgg
     8581 catcagttaa gcttaacaag ggcaactatg aattcagagt aatgaatcag gatgttcgtt
     8641 attgttgcgg ttacacatac aaggacttta cagtcggaag ccagttcagc tcaaagtggt
     8701 cgagtgcgtc aacgcttgca gcatcaggcg gtacatatac attcagctat gatattgata
     8761 caaacaagct tacaatatca tatcttcctt caggagcaga agtaagtgta gtaggtaact
     8821 ttacacttgc ccttgcaaag acagataaag aaaatgtata ttcaggtaca aagacactta
     8881 aggcaggaaa atatcagata aagatgaata actacggcaa gctctgcgga acatcagcgg
     8941 tagtaaagga tgcaacaccg ggtcttgtat tcagtccaaa gtggagcaag tacacaacat
     9001 ttgtagcaac aggcggaaca tacacattca catacaacac agcaacaaat aaacttgtag
     9061 tgacagcaga taagggagat attccggtaa aggtaacagg agatatcaac cttacactca
     9121 agaagagcga tacaaatgta tttacaggtt cggtaaagct taaaaggggt gaccactcgt
     9181 ttaagatgaa tgttaacggt acagatttct gcagcggtgc aacaatcaga aatgcaacaa
     9241 caggtactgt taagtacaac tcaaagttta caagtgcaac aacacttgta gcaattggcg
     9301 gtacttacac atttacttat aatacactta caaatcagct ttctgtgaag tattctaagt
     9361 aaatcggctt agcatcaaca gaatataatt tcaagcactc cgcacatcag tgtggggtgc
     9421 ttttttttgc tcaatatcaa tagttagttg ggctaacccg aaaaaacgga atctgcgctt
     9481 cttgagaaac aaatttttcg aatgcaggaa tgatcttgat tatatgtttc cgataatcgt
     9541 gaatattatc agtgtgtttt ccacacacag gatattcgtg catttttagt tcaagcttgc
     9601 agtaaatatg aatggtgctg tcaatttctt cgatgtttta aattaaaatg ttttgcaatg
     9661 ccaagcgttt ttctgtaaaa tatctttaga gcatattttt cctccgtttc aggtttttaa
     9721 gcaattccat tttaacggat tttggtaaaa taagctctac ttttttgctt ttcatttgta
     9781 ggcttttttc tacccaaact tttattatag agccgaaata aataatattg caaaaatcag
     9841 taaaataata cgcatactca gtgtaaattg caccgaggat gcgtttcttg aattattgat
     9901 atttaaagtt cttctctgac ttttttaccg tttcgtttta caatatatgc cctactgccg
     9961 acaacaacac aatctgaagg gacatcttta acgattattg ctcctgcacc gattatgaca
    10021 ttgtcaccaa tagtaacatt tccgagaact tttgcacctg tcattatttt aacattgttt
    10081 ccgatttttg gtctgccttt ttctgtgtga ccaaccgtaa cttgctgatt tatccaacaa
    10141 ttacttccca tagattcaac ccctacaatt gtagaaaatc catgttgtat aaataagccg
    10201 ggtcccatat ttttactggt taagtacagc gaatccaagg gcttgcaaaa aattttcaaa
    10261 aaatatttta tatttccaag acgcagataa aatacatttc tgaattcctt aaaatgacac
    10321 atcatataga aaaataagta tgtataactg caattgtttt ttttaggaca aagttttctc
    10381 caactttcaa gatccttgca tagaacatcg tgtttttcac agagtttaaa tacaaagaaa
    10441 tgcggaagaa gaaaaattga gcgtaaggca aataataatt tcataaatcc tcctgaggtt
    10501 caataatcaa tgaagcttgg ataccttgtt ttttaggcta taaaacttca tctttattca
    10561 ttattcttct tttgattttc tttattataa ttttgttgta atatttttta aatgtctttt
    10621 caaaaccgtt tttataatag aaattccaga aatcttctcg actgtcgggt tttgcggtag
    10681 ggcatgacag attagggtta gactttattg aagcgttaag gtcacattct acacaatgaa
    10741 tattgccgat tactttgttg agaatacgag atcctttttc ggaatttacc aacaataaag
    10801 aaactccctt gttgtcattg aaattttcaa ctacacggtc gattccccag aagtcagcaa
    10861 gtgtgagatc ggcgggtcta tcaaggtttg aatacttaca attatagcag gatggacgct
    10921 caatatcgtc ttcgtagaat agatatgtgt agccgttaag aatatgctta ttgtcatcaa
    10981 tccaaatcgc ttccttgtgg gtattccagc ctatagtttt atcacgaaaa tctgccttgg
    11041 ttacttttcc gcaaaacttt ttttcacaat gtttgaggta ctctttccat ataataggag
    11101 agggaactcc gtgacaggca atgtcacatg tatagagttt tgaggtgtcg catttaccaa
    11161 gatatctttt aagtccggca acttgacagg ctgttccgga aaacatgaca tacatatcgt
    11221 tatttaaatc atttttgaca gatttaaatg tgtctttcat atcgctctgg acatattttg
    11281 agcccttaaa cttatctctg acataacgat ccgttgctct tatgtggctg actgagaaat
    11341 catcctgaaa cgcagcaccg taaacagaac cttttttatt aagaatataa tcggataagg
    11401 ctacaaatgc agcaccgctg cggcttgtaa agcgagtatt aaagtcttta tgcttgattg
    11461 catatgctgt ctttgaatgg ttcttttcat aaccgttctg aaatgcgcat attttttggc
    11521 aggcgccgca ttcaatacag agtgagacat caatttgtgg gtagagaaaa ccttctgaat
    11581 caggcttcat agctatagcg cctttaggac atatctgttt acaggctgaa catccgcagc
    11641 attcactttt tgaaggaaaa atctgcatat ttattcccct ttaattatat ctttaaggta
    11701 atcaagcgag agtttgcgct ctgcttgaag tatgttatcg actttattcc agtcaatatc
    11761 tgttgtaacg gcttccccgt ctttaatttc tcggtttatg cctattgtct gaagaagatt
    11821 ttttgcacgg tgattaaatc cttttgctgt ttcatattca acaaacatat ttttgtgaaa
    11881 aattacagaa aaagcagttc cgtgaaatga attggttacc gtataatctg cgtttgcaaa
    11941 ataaccaaga aattcttcaa ctgttggggc agatacatag gtgaaatttt tacgcttttt
    12001 ttgtggatta tctgttatat aaacaacggg aattccggtc ttttttgaaa gtttttccgc
    12061 aaaatctatc agtgatttta caggttttac attaaataca agaatatatg gcttatcaat
    12121 tttttttaca gaaatctttt gccattcatc tttgttcaga agaagtgtag ggtcaatatg
    12181 acacacaccg ttcttaccgg ttatcttctt tacaatattt aatgcgcttt tttcacgaac
    12241 tgaaaaagac tgaaaatttt taagtaaagg tctgagctgc attgccttta catcgcttat
    12301 atctgcaaca ccaaaacttg ctgcataact gtatttttgg ttatcgtctg caaagctcag
    12361 aaaatagatg gaatcaggat ttattccttc cttaccggga ccccacacct gatcgcttcc
    12421 gctgatgaaa gcatcataaa gatttttgca ttctgatata tccgaattac tataggtttt
    12481 attgctgatt ttaagataat tgttgtagaa gcttgaaaac tgttcaattt ttttagctct
    12541 cttgcgatac ataacaatgg atttcaaaat tgacttaata ggatcagttt tgctaaactg
    12601 aaacggtttg tagccattgt cgatattttc acatttataa tctacgattt cacagtcact
    12661 tccaagctgt ttaagggtgt gttgaagtgc atacgcctgg agaacagcgc cgtaattttt
    12721 ggcacgatga aaagtaatta ttccaatttt tttcatatcc gttaaatctc cttatgaatg
    12781 cttgtacagc aggtaaccga tagggcttgt taggagaacg agcaatctgc ggggcttagt
    12841 cttgagcata gtcaatattt cactaagttt gtagccgttt gcaagtccat cacgggttat
    12901 tgccacgatg tgttcaaggt aacgctttcg attgtatttt ctgtaatccc aacagtcatt
    12961 tatataatgc agatgcatga caaatttttc ttttgatgcc ttttttctgt tgacatttgt
    13021 aacagcattt tcctgatctt gaatatagta tctcaatgct gtgcttaaat atctgcatat
    13081 atattttctt ccaacattat gccagataac attttccggg tagaagtgat agccttcgac
    13141 agcaggaaat ggaaattcac gcataatatc ggttctaatc ataccccata attcccctgt
    13201 gatattgagt ttaaaacgca aatcaaggtc attgctgtca atatacggaa cattcatttg
    13261 tgttccgtta attttaccat ccttatcata tgtacggcag gatataccgt aatatttttt
    13321 ttgctcctgt ttaggaattt tattccattc atttacaaat gtttcaaggg cgtcatttgt
    13381 acaggtatca tcagagtcaa gcgtaatgaa aaagtttccg ctgcacattt ttacagcatt
    13441 gtttgtggct atatgcttgc cttgattttt ttgataaaca taaataatgt caaaaaaatt
    13501 atcttctttc agaaatccgt cgacaacatc ctttgtatta tcttcactgc cgtcatctat
    13561 aattatccat tcaaagcttt tataggtttg ttttttcaaa cattcaaaaa ctcttggaag
    13621 agtttttgca cgattatatg atggggtaaa tacagttatt tcaacattac tcataattaa
    13681 ctccatttca tttttttgta agcttatttt tgagcttgca aagttccgct ttattaaata
    13741 acaacggcaa ggacaaggta tatgcaagga ttccgcatat agcacatatg aatataaatg
    13801 aactccaacc ggttactgta attaaattgc tgataattga gaataatacc aatataatga
    13861 taaatccaac acaatctcgg attactgtcg ggaaaaatat tgaaagtttt tgctttagta
    13921 tgtatgcaga atatgcaggg gtaaagatga gtgcacgcag tcccataaga acggaactcg
    13981 ttcctgctac aaaatatacg ccatagtcgg tgaggttaca ggctgcaatt gcaactataa
    14041 cgctgacaat gccaactgta aggtttacaa atacaggtaa tctaagttta ttacatacgg
    14101 tgtttatcat cataagcgac tgagtttgac tggaacaaag aaatgtaata caagtcaaca
    14161 ccgacataaa ctgaatcatt gtaatctcct ccggtgactt tgtcggttgc cataatatgt
    14221 agaactgtct gccaaaggca ataaaaccgg caataggagt cgagagtata aagcttacaa
    14281 ttttggtact gaatttcgcc tcgataatta gctccggtat ttttttcttt gcataaagaa
    14341 ttgtgtaatg aggagtaaat actgaaccta aaattacagt taggttgccg atactgttcg
    14401 gtacggtttt tgcgatagag agaagtccca tcagtgccgt tccaagggtt aggttgcata
    14461 tcagaagatc aagaccgctt agaagcacct gacaaagttg tgcaagtgaa agccaaatgc
    14521 cggacgcaag aagtgtttta actattttaa tgtcaaattt tctaatatca gcctttactt
    14581 ccgggagtac cttcttttta acagtaatat ttgccagcaa aaggaaaata ccgcttccaa
    14641 aacttgcaag ggtaacaaag taaagctgtg cagggaaaat tgcaaataaa agtactatga
    14701 gtgcaacttt tataaggttg gatataatat ctcgtataga atttatatca attctgtttt
    14761 ttacaaaggc tgctgttgtg aaaatagcag taactgtgct gacaacaaat gtgagaaaag
    14821 caaaagcaaa ggttattttt acgccggata caagatttga aggtatttta agcacagtgt
    14881 caagaaaaca aacaaaaatt gacgacagaa tcaacattac tgcagcgagg aacaaatcgg
    14941 caacgagaac cgaactgaat atttttgatg atttctcaac atcgccctta tggtatgcaa
    15001 tcgaaataaa tctgcctgaa attgaattca aagcggttgt aacgatggta gcatactgta
    15061 caaagttatt agcaagaccg ataaaaccat aggcatcact gccgacctct tttacaagat
    15121 acggtgtcag aaaaaagtta attccaacag taactgcaaa tgaaacgata cttgcaatta
    15181 tgtttatcga catttgtttt ccggcggatt ttggcattaa acggtcacct ctgaagattc
    15241 gttctgtatc agttccttta ttttgtttat atattccttt gatttatttc tttcctttaa
    15301 aagtacattg tcaacccttt cccaattaac cgcaccgttt atatttggaa aaacatcatt
    15361 tgttatctcg cgatcattga ttccaagatt gttaagaagt tcttcagcac ggatgtttct
    15421 gccaccgata tgttgcaatt caactgcaaa attcttttta tagattaccg aaaaggcagt
    15481 gccgtgaaat gaatttgtgc aaatatattc tgcgtttttt attaaaccta caaattcagt
    15541 ggcattcacc ggatcgaggt actctatacc gtcaatctta tggagcctct ccttttgcag
    15601 gtagtagatt ttgtatccgg tttttttaga aagttcaaga gcgtagctga taagtttaat
    15661 tggctttctt acgctgaaca gaaaaatata cggttctttt ggtacaggac atctgcttat
    15721 tttatcccaa tcatcttcag taagcaacaa cgagggatca atactgattt cagcttttct
    15781 gttgataaga ttttcaataa tatctgctcc gcttttttca cgaactgaaa agagctgaaa
    15841 ttgtgataac aactctttat atgtatgttc cttatcagca ggaagcttat caactgcaaa
    15901 gcttgccgca taggagtatt tttgctttgg ttttgcaaaa tcaagtaaat ataccgtatc
    15961 aaagccaacg cagatgggac tccacacctg atcgctccct gcaataaatg ctgcatattc
    16021 attggaggct tccccaatgt ttttggcatc aaaaggacga ctgaggttta aaaattcgtt
    16081 tctgaatgta acggactttt ttctgtcaat tcctacttga cgcatagtga tgagtgaacg
    16141 gataaatgac ttcaactt
//
