LOCUS       c00032_gnlPro..        15380 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LAIFGBKF_32.
ACCESSION   c00032_gnlPro..
VERSION     c00032_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:25:32
            Original ID  :: gnl|Prokka|LAIFGBKF_32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15380
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..147)
                     /locus_tag="ctg32_1"
                     /transl_table=11
                     /translation="MIFERYAFNRVHRTRTGEHGSPLQFFTFNFQLARGQSHCRDCPLA
                     FGDI"
     protocluster    1..15380
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1133:5380]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1134..5380
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..15380
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15380
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(193..990)
                     /locus_tag="ctg32_2"
                     /transl_table=11
                     /translation="MKKRLKGFFQRLARWLNVREMRQHRVKAGVYIIIRLILVSLLTAG
                     ILNGKWENVMTCVLTLGLLMLPLFIDRKLSVALPSVLETIVVLFVFAANVMGELGAFYE
                     KIPIWDSLLHTVNGFICAGVGFGLTDILNRSERVKLSLSPMFVCLFSFCFSMTVGVVWE
                     FFEFGADMLFEKDMQKDTVITAIHSGLISGKPNVIMHIRDITSTVVNGENLGINGYLDI
                     GLIDTMKDLLVNFVGAVVFDTIGWFYLKGRSAGFLRNFIPVKK"
     CDS             complement(1134..2459)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_3"
                     /sec_met_domain="HGD-D (E-value: 2.6e-27, bitscore: 86.4,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELKYDKKTGRLLFTKQMKKEYTILMPNMAPIHFKILEKVFNYY
                     GYKSDLLDTTGPEIAQTGLKYVHNDTCYPALLVIGQFINALQSGKYDVHKVALMITQTG
                     GGCRASNYIFLLRKALKKAGFEFVPVISLSFGMEHNSGFSLTLPLIRRFVGGLVYGDQL
                     MLLSNQTKPYEVNKGESMALVDEWTDKISDMLIKGKGYTLEEIDETLDKITKSFTKIEL
                     NKVPKVKVGIVGEIYVKYSKMANNGLEDFLADQDCEVCVPGLMGFASFKVDNRIEDYKM
                     FGGSRVKYKFCSMLLNYLTKLEGLMVDAAEKYGFVPPHRYAHTKELVNGVIGYGSKMGE
                     GWLLTAEMIELADTGYENIVCTQPFGCLPNHINGKGAIRKIKEIRPNANIVTIDYDPGA
                     PKVNQENRIKLMLAVGKEELKKKLEAEKNGEKAESSEKSEKK"
     CDS             complement(2477..5380)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_4"
                     /sec_met_domain="HGD-D (E-value: 6.4e-18, bitscore: 55.6,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 6.9e-39, bitscore:
                     123.9, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKLGLDIGSTTIKCVVLDDENKLIYSTYERHYSRITEKIAEILAL
                     VRTRIDGVENASVALSGSAGMGVAESVGVDFIQEVYATRVAANTFIPGTDVIIELGGED
                     AKILFLTNGLEVRMNGTCAGGTGAFIDQMATLLNVKLEDMDELAKQHEKTYTIASRCGV
                     FAKTDIQPLLNQGARKSDIAESIFNAVVSQTVAGLAQGREIEGQIVYLGGPLTFMSELR
                     NCFDRTLGTKGICPENSLYYVACGAALCAEKTIDFDEVIEKVKNYRGSGNFAFNQPLFK
                     NEEEYKEFCDRHAKADVKQKELKGYTGKAYIGMDAGSTTVKGVVLNDDGELLYSKYLPS
                     KGNPVEIMKQFLDEVYEINPEINVVSSAVTGYGEDIVKNAFAVDYGIVETIAHFTAAKY
                     FMPDVEFIIDIGGQDIKCFKIHNGAIDNIFLNEACSSGCGSFLQTFANALGYEIADFAK
                     LGLFAKRPVDLGSRCTVFMNSSVKQAQKDGATIEDISAGLSLSVVKNALYKVIRASSPD
                     ELGKRVVVQGGTFLNDAVLRAFEQEMGVEVVRPNIAGLMGAYGAALYAKKKSKGIGKST
                     ITDKKGLDEFVHEIKVANCGMCNNNCRLTINSFGKGRKFIAGNRCERPITKKAPANDMN
                     MYAYKLNLIDSYKPVEGIRGKLGIPMALNMYELYPFWYRFFTELKFEVFHSPYSTRKLY
                     QRGQQTIPSDTVCFPAKLVHGHIQTLIDMGAETIFYPCLSYNFDEHLGDNHYNCPVVAY
                     YPEVIKNNMKDIRKVHFIKEYFGIHRPNDFPKKAYERLSFHFPDLTLNEVRNAAKLAYQ
                     EQENYRKKVIDKGNEIIAKAEKEGKKIFVLAGRPYHIDPEINHGIDRLISGFDVAIVSE
                     DVISPRVEHFRTHVLNQWTYHARLYAAAKYVTTRKDMELVQLVSFGCGVDAITTDEVRE
                     ILESKNKIYTQIKIDEITNLGAVKIRIRSLLAALEND"
     CDS             complement(5666..6271)
                     /locus_tag="ctg32_5"
                     /transl_table=11
                     /translation="MTILDSVKGTVNTAVDTISSVAQTIVEKNRTNAKLNRLRLVMKSE
                     SELMNRAYIALGKIMYDSRKKGAEINDAECEKLLKVIDTSKAKIAKARECYRKIVNSSN
                     DIFYGNPEVAPEVKKDDIVDITVACSNEGDYKSSPFKEEKPVEKQPEAVTEEKADPEPL
                     TNICDLKAELEAKREEGFSESADSDEADDGEAPHGELF"
     CDS             6464..7162
                     /locus_tag="ctg32_6"
                     /transl_table=11
                     /translation="MPEKKITKAIVCPMCGEMSKADVYTSINPSVTKGVRRRALDGELF
                     AWKCPSCGYSARLTYPILYNDMKNRFMVYFIPKIDHFQLCDNELEEKYSNLRNISKRIV
                     PTFNSFKEKIFIFESGLDDMSVELTKLAISQTVSKKLNGAEIHDGYLSMYDRERNTMGF
                     TYFTGEKHTPYVQTARLEIYVKSKKIVDSLAYKDKKLKGFLKIDREWAENILYRYKRMK
                     HIEKLNKLKE"
     CDS             complement(7460..8464)
                     /locus_tag="ctg32_7"
                     /transl_table=11
                     /translation="MAVTFEGMERRMPKIEKCLAEYGIANLEEARKICNDLGFDPYDIV
                     KGVQPIAFENAGWAYTLGCAVAVKKGAKTASEAAEAIGIGLEAFCIPGSVAEQRNVGRG
                     HGNLGAMLLRDETKCFAFLAGHESFAAAEGAIGIARNANKARKEPLRVILNGLGKDAAY
                     IISRINGFTYVKTQFDYFTSELKIVEERAFSDGERAAVRCYGADDVREGVAIMQHENVG
                     VSITGNSTNPTRFQHLVAGTYKKWANENGVKYFSVASGGGTGRTLHPDNMGAGPASYGL
                     TDSMGRMHGDAQFAGSSSVPAHVEMMGLIGMGNNPMVGATVACAVAVYEAVNK"
     CDS             complement(8486..9178)
                     /locus_tag="ctg32_8"
                     /transl_table=11
                     /translation="MIYSKEVENMCTVAKGPKHGPAPIPEEGKWVKSYDIKDISGLSHG
                     IGWCAPQQGACKLTLNVKDGIVEEALVETIGCSGMTHSAAMAAEILPNKTLLECLNTDL
                     VCDAINTAMKNIFEQLVYGRSQTAFSEGGLPIGAGMEDLGKGLRSQVGTMYSTNAKGVR
                     YMEMAEGYVLKTALDENDEVIGYQFVKLGKMLEDIRHGVEPNEAYKNNIGQYGRFDGAA
                     KYIDPREE"
     CDS             complement(9392..9586)
                     /locus_tag="ctg32_9"
                     /transl_table=11
                     /translation="MKNLRLKSARAAKDLSQQQLAELVKVSRQTISAIEKGDYNPTINL
                     CIAICKALDKTLDELFWEE"
     CDS             complement(9583..10104)
                     /locus_tag="ctg32_10"
                     /transl_table=11
                     /translation="MGEKYYWVLGFCCGFIAVVIVTLIIANIKRKKNTYTEYDERQVLA
                     RGKAYKSAFFVLIGYIIACALVNVLEINWAELSVQMFIGLFLSTAVFVGISIFNDAYFT
                     SNKGRKSLLGVLVFIAGAEYLGIAFGKKTFVTNGIANLDIIPIIVMIWAISIFVMVVIK
                     TIIDKKAVEE"
     CDS             complement(10400..10597)
                     /locus_tag="ctg32_11"
                     /transl_table=11
                     /translation="MAENKNSRARIEANNRYNAKAYDRINVAVPKGRKDIIKAHAEKNG
                     ESVNGFVNRAINETIQRDGE"
     CDS             11744..12352
                     /locus_tag="ctg32_12"
                     /transl_table=11
                     /translation="MKAKGVGNKPAPYLLVFTLFLGAVYLSAIFRTGYFCRQEGSEFMA
                     KSKGGVTVSKVWELCQPIVEGFGLSLWDVRYVKEGADRFLRVYIDKPEGIDINDCENVS
                     RAINGPLDELDPIEEAYCLEVCSPGIERELIRDEHFMQFIGADIMVKMLRPIDGIGREF
                     KGVLKDYSDGKVTIEDHSGENEITISKKDAAWIKLDDFD"
     CDS             12434..13594
                     /locus_tag="ctg32_13"
                     /transl_table=11
                     /translation="MTNKDLFEALRTFEKEKGIPMDYMLQNIEKAISVACKNYYGGNEN
                     VVFKVDPEKNSFDAKLVKTVVDEVFDPNFEVTVEEAQQINKRKKFIVGDEIEVPIDPKH
                     LGWTSVSSARNVIRQGIRQGEKGQTLIEFQSKLGEIVTATVERIDPKSGVATIKIGKSE
                     ATLPKSEQLGHDDLKEGDHIKVYIADVKDNERGPHAIISRTHPGLVKRLFEQEVPEIYD
                     GVVEIKSISREAGSRTKMAVYSSNPDVDAIGSCIGNKGARVNKIVEELGGEKIDIVLYS
                     DDPEKYISAALSPASVCKVEITDEETKSCRATVPDGQLSLAIGNKGQNARLAARLTGWR
                     IDIRPESGFYGEDEDDEPKTEEKSEDVLDLDESTEGETVVSDETEE"
     CDS             13619..13927
                     /locus_tag="ctg32_14"
                     /transl_table=11
                     /translation="MKQRKMPLRKCTGCGEMKEKRELIRVVKAPDTKDENGEIIAKGEI
                     SLDLTGRKAGRGAYVCRNLACFEKARKARRFERSLSCKIPDEVYEQMQSELAAADSK"
     CDS             13943..14275
                     /locus_tag="ctg32_15"
                     /transl_table=11
                     /translation="MNDRILSLLGICKRAGKLITGADTTIDSIRKSKAKLVIFANDFSK
                     SSKKSVQTAADECNVKALTMNRSKEEIGFALGKICGVMTTEDKGFADKLEQLIENESGG
                     ELYDKI"
ORIGIN
        1 aatatcacca aaagcaagag ggcagtcacg gcaatgtgac tgccctcttg ctaattgaaa
       61 attaaaagta aaaaattgca ggggtgaacc gtgttcgccc gttcgtgtgc gatgcacacg
      121 attgaacgca tagcgttcaa atatcatatg caactcattt atataatttg attttacata
      181 aacattgcgt cattattttt taacggggat aaaattccgc aaaaatcctg cacttcttcc
      241 tttcaggtaa aaccaaccta tggtgtcaaa aactaccgct cctacaaaat taacaagcaa
      301 atctttcatt gtatcgatca gaccgatgtc aaggtaaccg ttaataccga gattttcacc
      361 gttcacaacg gttgatgtta tatctctgat gtgcattatc acattcggct tgcccgaaat
      421 caaacccgaa tgtattgccg tgattacggt gtccttttgc atatcctttt caaaaagcat
      481 atccgcacca aactcaaaaa actcccacac aacaccgact gtcattgaaa agcagaacga
      541 aaacaggcac acaaacatgg gcgagaggct caatttcacc cgctcgcttc tgttcaaaat
      601 atcggtcagt ccaaaaccaa cgcctgcaca gataaagccg ttcacagtat ggagcaatga
      661 atcccatatc ggaatctttt cgtagaacgc accgagctca cccataacat ttgccgcaaa
      721 cacgaacagc acaacaatcg tttcaagcac actcggcaac gctaccgaca gctttcggtc
      781 gatgaacaac ggaagcatca acagtccgag cgttaacacg caggtcatga cattctccca
      841 ttttccgttt aaaatgccgg cagtcaaaag tgacacaagt atgagcctta taatgatgta
      901 aacgcctgcc ttaactctgt gctgtcgcat ttcacgcaca ttcagccacc gtgcaagcct
      961 ttgaaaaaat cctttaagtc gttttttcat aatatccccc gatttttaca cttatttttt
     1021 ccttaaaaac gagataaacc cctgtaaaat tgtattagct gtttctgcct gatattaccg
     1081 caaaataaaa aagccaccgc catctgcgat gactcataag cattgatatt aaattacttt
     1141 ttctctgact tctctgacga ttcggctttt tcgccatttt tttcagcctc aagctttttc
     1201 ttgagttcct ctttgccgac agcaagcatc agcttgatac ggttctcctg atttaccttc
     1261 ggcgcacccg gatcatagtc gatggtaacg atattggcat tcggtctgat ttctttaatc
     1321 tttctgattg cgcccttacc gttgatatga ttcggcagac aaccgaaagg ctgtgtgcat
     1381 acgatattct catagcctgt atcggcaagt tcaatcatct cggctgtcag caaccaaccc
     1441 tcgcccatct tactgccgta gccgataaca ccgtttacca gctcctttgt gtgagcatat
     1501 ctgtgaggcg gaacaaagcc gtacttttca gcggcatcaa ccataagtcc ctcaagcttt
     1561 gtgaggtagt taagaagcat cgaacagaat ttgtatttaa ctctgcttcc tccgaacatc
     1621 ttgtagtcct caatacggtt atcaacctta aatgatgcaa aacccataag accgggtacg
     1681 caaacctcgc aatcctgatc tgcaagaaag tcctcaagac cgttgttagc cattttggag
     1741 tattttacat agatttcgcc gacaataccg actttaacct tcggcacttt gttaagctca
     1801 atttttgtga atgactttgt aattttatca agggtttcgt caatttcttc aagagtgtag
     1861 cccttgccct ttatgagcat atcggaaatc ttatccgtcc actcatcaac aagcgccata
     1921 ctttcgccct tgttcacctc atagggcttt gtctggtttg aaagcagcat taactggtcg
     1981 ccgtacacaa gaccgccgac aaatctgcga ataagcggga gtgtgagcga aaaaccgctg
     2041 ttgtgctcca taccgaatga aagcgaaatt acgggaacga actcaaagcc tgcctttttg
     2101 agagcctttc tcaaaaggaa aatgtagttt gacgcacgac atccgccgcc tgtctgagta
     2161 atcatcaggg caaccttgtg aacatcatac tttccgcttt gcagagcatt gatgaactga
     2221 cctataacca gcaaagccgg ataacaggta tcgttgtgaa catatttaag acctgtctgc
     2281 gcaatctccg gacccgttgt gtcgagcaaa tcagacttat agccgtagta gttgaacacc
     2341 ttttcaagta ttttaaaatg aataggcgcc atattgggca taagaattgt gtattccttt
     2401 ttcatctgct ttgtaaacag caaacgacct gtttttttgt catacttcaa ctctgccata
     2461 acagaatttc ctttcatcaa tcgttttcaa gcgcagcaag caaactgcgg attcggattt
     2521 taactgctcc gaggtttgta atttcatcta tcttaatctg agtgtaaatc ttatttttgc
     2581 tttcaagaat ttctcttacc tcatcggttg taatcgcatc aacaccgcag ccgaaggata
     2641 caagctgaac aagctccatg tcctttcttg ttgtaacata ttttgccgcc gcataaagtc
     2701 ttgcgtggta tgtccactgg ttgagaacat gagtccggaa atgttcaact ctcggagaaa
     2761 taacatcttc gctgacgatt gcaacatcaa agcctgagat aagtctgtcg attccgtggt
     2821 taatttcggg atcaatatga tatggtctgc ctgcaagaac aaaaatcttt ttgccctctt
     2881 tttcagcctt ggcaataatc tcgttgccct tgtcgataac cttttttctg taattttcct
     2941 gttcctgata tgcaagctta gccgcatttc ttacctcgtt aagagtgagg tcggggaagt
     3001 ggaacgaaag tctttcatag gctttcttag gaaaatcgtt cgggcggtga ataccgaagt
     3061 attcctttat gaagtgaacc ttgcgtatat ccttcatatt gtttttgata acctcggggt
     3121 agtaagcaac aacaggacag ttgtaatggt tatctccgag atgctcgtca aaattatagg
     3181 aaagacaggg gtagaaaatt gtttctgcac ccatatcaat aagagtctga atgtgaccgt
     3241 gaacaagctt tgcagggaag caaacggtat cgctcggaat tgtctgctga cctctctgat
     3301 aaagctttct tgttgaatac ggtgagtgga acacctcaaa tttaagttct gtaaagaatc
     3361 tgtaccagaa cggataaagc tcatacatat tgagcgccat aggaattcca agcttacctc
     3421 ttatgccttc aacaggcttg taggaatcaa tgagattcag cttataggca tacatattca
     3481 tatcgtttgc aggagccttc tttgtgattg gtctttcaca acggtttccc gcaataaact
     3541 ttctgccctt gccgaatgaa tttattgtaa gacggcagtt gttgttgcac ataccgcagt
     3601 ttgcaacctt gatttcgtga acgaattcat caagtccctt tttgtcggta attgtactct
     3661 tgccaatgcc ctttgacttt ttctttgcgt aaagagccgc accgtaagca cccataagtc
     3721 ctgcaatgtt aggacggaca acttcaacgc ccatttcctg ttcaaatgca cgcaaaacag
     3781 cgtcgttaag gaaagtacca ccctgaacta caacacgctt gccgagttcg tcggggcttg
     3841 acgcacgaat aaccttgtaa agggcattct ttacaacgct gagtgaaaga cctgccgaga
     3901 tatcttcaat tgtagcgccg tctttctgag cctgcttaac gcttgaattc ataaatacgg
     3961 tacagcgtga gccgaggtca acgggacgct ttgcaaaaag tccgagcttt gcaaagtcgg
     4021 caatctcata tccgagagcg tttgcaaaag tctgcaaaaa gcttccgcaa cccgatgaac
     4081 aagcctcatt aaggaatata ttgtcaattg caccgttatg tatcttaaag catttgatat
     4141 cctgtccgcc gatatcgatg ataaattcaa catcgggcat aaagtatttt gcggcggtaa
     4201 agtgggcgat tgtttcaaca atgccgtaat caaccgcaaa tgcgttcttt acaatgtcct
     4261 ctccgtaacc tgttacggca gaagaaacaa catttatttc gggatttatt tcgtaaacct
     4321 cgtcaaggaa ttgcttcata atctcaacgg ggtttccctt tgatggcaga tattttgaat
     4381 agagcagctc accgtcatca ttgaggacaa cgccctttac ggttgttgag cctgcgtcca
     4441 ttcctatata agccttgcct gtgtatccct ttagctcctt ctgcttaaca tcagcctttg
     4501 catgacggtc gcagaattcc ttgtactcct cttcgttttt aaagagcggc tgattgaacg
     4561 caaagttacc gctgccacgg tagttcttta ccttttcgat aacctcgtca aaatcaatag
     4621 tcttttcggc acacaaagcc gcaccgcagg caacataata aagtgaattt tcggggcaga
     4681 tgccctttgt tccgagcgtg cggtcaaagc agtttcgcag ttcgctcata aatgtaagag
     4741 gtccgccgag atatacaatc tgaccttcaa tttctctgcc ctgtgcaaga cctgcaacag
     4801 tctggcttac aaccgcattg aaaatactct ctgcgatgtc gctcttcctc gcaccctgat
     4861 taaggagcgg ctgaatatcg gtctttgcaa acacaccgca tcttgatgcg attgtgtatg
     4921 tcttttcgtg ctgttttgca agctcgtcca tatcctcaag cttaacattc agaagtgttg
     4981 ccatctggtc aataaacgca cccgtgccac cggcgcaggt accgttcatt cttacctcaa
     5041 gtccgtttgt gaggaacaat atctttgcat cctcaccgcc gagttcaatt ataacatctg
     5101 tacccggaat aaaagtattg gcggcaactc ttgttgcgta aacctcctga ataaaatcaa
     5161 cgccgacaga ctcggcaaca cccattccgg cagaacccga aagagccacc gaggcatttt
     5221 caacgccgtc aatccttgtc cgtacaagtg caagaatttc tgcaatcttt tccgtaattc
     5281 gggaataatg cctttcatat gtgctgtata ttaatttgtt ttcgtcgtca agcacaacac
     5341 attttattgt tgttgagcca atatccaatc ctaatttcaa cttgtgcctc cgaaatcaat
     5401 acatagtaat ctcattgtgc atatctaatt aattatagta ttttttgtca agaaaataat
     5461 tctaatttgg aatattttca cctttgatga attttaccat ttttatcaca aaaattcaat
     5521 acacataaag ggcataatgt ataatctact gcatataatt tgccctcaaa agcgaagcgg
     5581 agcattgttc cgactttaat atatcttaaa aatgcagaaa aacctgccga aatcggcagg
     5641 tctttagctt taagtattta aattatcaga aaagttcacc gtgaggagct tcaccgtcat
     5701 ctgcctcgtc tgaatctgcg gactcggaga atccctcttc acgctttgcc tcaagctctg
     5761 ccttgaggtc gcagatgttt gtaagaggct cggggtctgc cttttcttcg gtaacagcct
     5821 cgggctgttt ttcaacaggc ttttcctctt taaaaggaga ggacttgtag tcgccctcat
     5881 ttgagcaagc tactgtaata tcaacaatat catccttttt aacctcggga gcaacctcgg
     5941 gattgccgta gaaaatatcg tttgagctgt tgacaatctt tctgtaacac tctcttgctt
     6001 ttgcgatttt ggcctttgaa gtgtcaataa ccttcaaaag cttttcgcac tcggcgtcat
     6061 taatttcagc gcctttcttt ctgctgtcgt acataatctt tccgagagca atatatgctc
     6121 tgttcataag ctcgctttcg cttttcataa caagtcttaa tctattgagc tttgcgtttg
     6181 ttctgttctt ttctactatt gtctgagcta ccgatgaaat tgtatcaacg gctgtattta
     6241 ctgttccttt tacactgtca agtatcgtca tagtaaattt ctcctttaaa accgctttgg
     6301 cacaaacact ctgacacatt ctgccgtggc gaataatatt aaacttattt ctattattat
     6361 gacagatttt tttgataaaa tcaacatttt tttaaaattt acttgttaaa atcacggtca
     6421 attgctataa ttagtttcat agagtgttaa agaggtggtt tggatgcctg aaaagaaaat
     6481 taccaaggca atcgtctgcc caatgtgcgg tgaaatgagc aaggctgatg tttacaccag
     6541 catcaacccg tccgtaacaa agggtgtgcg cagaagagcg cttgacggtg agctttttgc
     6601 gtggaaatgt ccgtcatgtg gatactccgc aaggctcaca tatccgattc tctacaatga
     6661 tatgaagaat cgttttatgg tgtatttcat tcctaaaatt gatcattttc agctctgcga
     6721 caacgagctt gaagaaaaat acagcaatct ccgcaacata agcaaacgaa ttgttccgac
     6781 cttcaattcg ttcaaggaga aaatttttat ctttgagtcg ggacttgacg atatgtcggt
     6841 tgagcttaca aagctcgcaa tcagccaaac ggtttcaaaa aagcttaacg gtgcagaaat
     6901 tcatgacgga tacctttcaa tgtacgatcg tgaacgcaac acaatgggat ttacatattt
     6961 tacaggtgaa aagcatacgc cgtatgttca gacagcaaga cttgaaattt atgttaaatc
     7021 gaagaaaatt gtcgattcgc ttgcgtataa agacaaaaag ttaaagggct ttcttaaaat
     7081 tgaccgtgaa tgggcagaaa acattctcta ccgctacaag cgcatgaagc atattgaaaa
     7141 gcttaacaaa ctgaaagagt aagctgttac tgtagtcagt caattctttt ggcttaaaaa
     7201 gcacctgcaa ataagtgaca tatgcactgt aaagaaaaca gctaaagaat attcgtaaac
     7261 ataaactcgt taaagcaaaa atgcataaaa atttccgcca ttacgattgg ggcggcggaa
     7321 tcattcagct taatattttt tgtatttgca attcaaactt gtcagaatgc tgatacaatc
     7381 ggggattttc gttgcacaaa aaaatcaggg atcgactcaa agagccgacc cctttttaat
     7441 ttattgaaaa gattggtaat tacttgttaa cagcttcata aactgcaact gcgcaagcaa
     7501 ctgtagcacc aaccatcggg ttgttaccca taccgataag acccatcatt tcaacatgag
     7561 caggaacaga agatgaacct gcgaactgag cgtcaccgtg cattctgccc attgagtctg
     7621 taagaccgta tgatgcagga cctgcaccca tgttatcggg gtgaagtgta cggcctgtgc
     7681 cgccgcctga tgcaaccgag aaatacttaa cgccgttctc atttgcccac ttcttgtatg
     7741 tacctgcaac gaggtgctgg aaacgagtcg ggttagtaga gttacctgtg atagatacac
     7801 ctacattctc atgctgcatg attgcaacac cttcacgaac atcgtcagcg ccgtagcagc
     7861 gaactgcagc tctttcaccg tctgagaaag ctctctcttc aacgatttta agctctgatg
     7921 tgaaatagtc aaactgagtc tttacatatg taaagccgtt gattcttgaa ataatgtaag
     7981 cagcatcctt gccaagaccg ttaaggataa cacggagcgg ctcttttctt gctttgttag
     8041 cgttacgagc gataccgata gcaccctctg ctgctgcaaa gctttcgtga cctgcgagga
     8101 atgcaaagca ctttgtttca tctctgagga gcattgcgcc gaggttaccg tgaccacggc
     8161 caacatttct ctgctcagct actgagccgg gaatacagaa agcctcaaga ccgataccga
     8221 tagcttctgc tgcctctgaa gcagtctttg cgcccttctt aactgcaact gcacaaccga
     8281 gtgtgtaagc ccagcctgcg ttttcaaatg cgatcggctg aacgcccttt acgatgtcgt
     8341 agggatcaaa accgagatcg ttacaaattt ttcttgcctc ttcaagattt gcaataccgt
     8401 attcggcaag gcacttctca attttaggca ttcttctttc cataccttca aatgttactg
     8461 ccattatggt gtcctcctta ccgaattatt cttcacgagg gtcaatgtac ttagctgcgc
     8521 cgtcaaaacg accgtactga ccgatgttgt tcttgtatgc ttcgtttggc tcaacgccgt
     8581 gacgaatgtc ctcgagcatt ttgccgagct ttacgaactg atagccgata acttcatcgt
     8641 tctcgtcaag tgctgtcttg agaacatagc cttcagccat ttccatgtaa cgaacgccct
     8701 tagcgtttgt gctgtacatt gtaccaacct ggctgcgaag acccttaccg agatcctcca
     8761 tacctgcgcc gatcggaaga ccgccctctg agaaagctgt ctggcttctg ccgtaaacga
     8821 gctgctcaaa gatgttcttc atagctgtgt tgatagcgtc acaaacgagg tctgtgttaa
     8881 gacactcaag gagtgttttg ttaggaagaa tttctgctgc catagctgca gagtgagtca
     8941 tacccgaaca accgattgtt tcaacaagag cctcttcaac gataccgtct ttaacattaa
     9001 gtgtaagctt gcaggcaccc tgctgaggag cacaccagcc aatgccgtgt gaaagacctg
     9061 aaatgtcttt aatgtcataa gattttaccc atttgccctc ttcgggaata ggtgcaggac
     9121 cgtgcttagg tccctttgct acagtgcaca tattttcaac ttcttttgaa taaatcatgt
     9181 gtacttctcc tttcaataaa ttgtatgagt ccgaaatcct caaacaccta tattatacgg
     9241 cttaacccga catttttcaa gcatttttcg ttaattttta caattccccc acattgtaat
     9301 atttcccgta gcaatttccc gtttgatttt gaaacgggaa aaataaaaac ggcaaccgag
     9361 aaataaatca ccgactgccg ttaaaatttg cttattcttc ccaaaacaat tcgtcaaggg
     9421 ttttgtcaag cgctttacat attgctatac aaaggttaat tgtgggattg tagtcgccct
     9481 tttcaattgc gcttattgtc tgtcttgaca cctttacaag ttccgcaagc tgttgctgtg
     9541 acaaatcctt tgcggcacgg gcacttttta atcttaaatt cttcattctt caactgcctt
     9601 tttgtcaatt attgttttga tgacaaccat cacaaaaata cttattgccc aaatcattac
     9661 aatgatagga ataatgtcaa gatttgctat tccgtttgta acaaaggttt ttttgccgaa
     9721 agcaattccc aaatattctg ctcccgcaat aaataccaaa acgcctaaaa gactctttct
     9781 gcctttattt gatgtaaaat atgcgtcatt gaaaatgctt attccgacga atacggcagt
     9841 tgaaagaaac agtcctatga acatttgaac gctgagttca gcccaattaa tctccaaaac
     9901 attaactaaa gcgcaggcaa ttatgtaccc gataagcaca aaaaatgccg atttataagc
     9961 cttgccccgt gcaagaacct gtcgttcatc gtattctgtg taagtgttct ttttcctttt
    10021 aatgtttgcg ataatgagcg ttacgataac tacggcaata aaaccgcaac aaaaaccaag
    10081 cacccaatag tatttttctc ccataataac atctcccaaa taaatcagcc aatttgcaga
    10141 tttattcgtc cagccgataa tccgcaaata atattaaaaa attttatgtg tttagatgtg
    10201 aatacttaaa aaatccacaa tgcgtacaaa aagctttacg taccattata gtacattaaa
    10261 agttacttat tgtcaagtat attttacata atttcaaaaa tacttttatt tggctgtttt
    10321 gggaaattaa atccgttaaa aaacctgtca actaaaacaa aataagacaa gcccatattt
    10381 cagagcttgc cttgtggaat tactcaccgt cacgctgtat tgtttcatta atagcacgat
    10441 taacaaagcc gttcacgctt tcgccgttct tttctgcgtg ggctttgata atatcctttc
    10501 gacctttcgg cacagcaaca ttgatacggt catatgcttt agcgttatat cggttgtttg
    10561 cctcaattct cgccctgctg ttcttatttt ctgccatttc ttcaccgcct aaaatctatt
    10621 gacatcaaat tattgttgtt gtataatata agtgaaaagg aacggcttta gctgtttcgc
    10681 atttgcgtat tttttttatt aaaaaccgct ctgtattgcg actacagggc ggttatttct
    10741 ttatattctt aatgacttca ttaaaagcca cgaaaacaat tgcgagaaca aacaagtatg
    10801 taatctctgc cattggaata cacccccttt cgcaagggag tcgaaacagc cgccaccgtt
    10861 cctttacaag tattattata gcatacccct ttacacttaa caagtaccaa tatgtaaaaa
    10921 ttacacactt aagcattgta tattatgcca attgaatgca cttaaacatt gtagtataat
    10981 atagtcacag gataaggaaa gaggaaagcg ataatcagta tgaccgcaac gcaattgcag
    11041 tatatgcaag atagattgta caagaataat attaatcagt ttggatttgg caacggtatt
    11101 gttttctaaa caacaataaa aaggtatcag tctttttaac caataccctt ttatggagct
    11161 gataactatt ctgtgcattg caaggagtgc atacctcgct tgttgcttgc ggtgcaaatt
    11221 ctgaacgctc atcaacgcta cgccctaaaa acgctttact aaagcgtttt ctaaacgggc
    11281 tttcgaatcc cttatcttaa tctgaaacaa caataaaaag gtatcggtct ttttaaccaa
    11341 taccctttta tggagctgat aacgggattc gaacccgtga cctcgtcctt accaaggacg
    11401 cactctgcct actgagctat atcagcatat ttaattgtaa ggttgcaacc tttataatgt
    11461 taatcccgca aaatttcgga cattaacagc caaatcattg atataaaaaa cagtaaaaat
    11521 ccaacaataa caaaatcaaa attaatttta cttttttcac acggtcgcaa aaccacggtg
    11581 attatatcac aaaaacatcg taatgtaaag tgtccacgaa atataataac acatttgcac
    11641 ggtgatttca aatgtttttt taaacttttt tgtaaaaaat acgaaaagat ttgaaaaaca
    11701 cttgattata agccgttttg gtgctataat tttcttgtaa ataatgaaag ctaaaggagt
    11761 gggcaacaaa cccgctcctt atttattagt tttcactttg ttcctcggtg cggtttatct
    11821 gtctgcaata tttcgcacag ggtatttttg cagacaggaa ggcagtgaat ttatggcaaa
    11881 aagcaaaggc ggtgtaaccg tatcaaaagt atgggagctt tgtcagccga ttgttgaagg
    11941 cttcggactt tcactttggg atgtgcgtta tgtcaaggaa ggtgcagacc gtttcctgcg
    12001 tgtttacatt gacaagcccg aaggcattga cattaacgat tgcgaaaatg tttcccgtgc
    12061 aatcaacggt cctcttgatg agcttgatcc gattgaggag gcgtactgtc ttgaggtctg
    12121 ctctcccgga attgagcgtg agcttatccg tgacgaacat tttatgcagt tcatcggtgc
    12181 ggatattatg gttaagatgc tccgccccat tgacggcata ggcagagaat tcaaaggagt
    12241 tttaaaggat tattccgacg gtaaggtcac aattgaggat cacagcggtg agaatgaaat
    12301 cacaatcagc aaaaaggacg ccgcatggat taagcttgac gattttgatt aaaaattgca
    12361 gtttgaacac tacggataca cataacagca taacaatata taaccgaaaa ataagaaaag
    12421 gatgatttgg aaaatgacta acaaagattt atttgaggca ttgagaacat ttgaaaagga
    12481 aaagggcatt cctatggact atatgcttca aaacattgaa aaggcaattt ccgttgcctg
    12541 caagaactac tacggcggta atgaaaatgt tgtattcaag gttgatccgg aaaagaacag
    12601 ctttgatgca aagcttgtca aaacagtagt tgacgaggtt tttgatccta actttgaggt
    12661 tactgttgag gaggctcagc agattaacaa gagaaagaaa tttattgtcg gcgatgagat
    12721 tgaagttccg attgatccca agcacctcgg ttggacatct gtttcttctg caagaaatgt
    12781 tatccgtcag ggcattcgtc agggagaaaa aggtcagact cttatcgagt ttcagagcaa
    12841 gctcggtgaa attgttactg caaccgttga aagaattgat cctaagtcgg gtgttgcaac
    12901 aatcaaaatc ggcaagagcg aagctactct gccaaagagc gaacagctcg gtcatgacga
    12961 ccttaaagaa ggcgaccaca ttaaggttta tattgcagat gtcaaagaca acgaaagagg
    13021 tcctcacgca atcatttcaa gaacacatcc cggtcttgta aagcgtttgt ttgaacagga
    13081 agttcctgaa atctatgacg gcgttgttga aataaagtca atctcccgtg aggcaggcag
    13141 tcgtacaaaa atggctgttt acagctcaaa tcccgatgtt gacgcaatcg gttcatgtat
    13201 cggcaacaag ggcgcccgtg taaacaagat tgttgaagaa ctcggcggtg aaaaaatcga
    13261 catcgtgctt tacagcgatg atcccgaaaa gtacatttcg gcggctctct ctcctgcaag
    13321 cgtttgcaag gttgaaatta cagatgaaga aacaaagagc tgccgtgcaa ccgttcccga
    13381 cggtcagctt tcacttgcta tcggcaacaa aggacagaat gcccgtcttg ccgcaagact
    13441 tacaggctgg agaattgaca tccgtcccga aagcggtttc tacggcgaag atgaggacga
    13501 tgaaccaaag acagaagaaa agtccgaaga tgttctcgac cttgacgaaa gcacagaagg
    13561 cgaaacagtt gtttcggatg aaacagagga ataatcagat taaacagaga gggattttat
    13621 gaagcaaaga aaaatgccgt tgcgtaaatg tacgggttgc ggagagatga aagaaaagcg
    13681 tgagcttatc cgtgttgtca aagcacccga caccaaagat gaaaacggtg aaatcattgc
    13741 aaaaggcgaa atttcgcttg acctcacagg tcgcaaggca ggcagaggcg catatgtgtg
    13801 cagaaatctt gcctgctttg aaaaggctcg caaggcacgc cgctttgaac gctcgttaag
    13861 ctgtaaaatc cctgatgaag tatatgagca gatgcaaagt gaacttgccg cagcagacag
    13921 caagtaggcg aaaggatttt ttatgaacga caggattttg tcgctgcttg gcatttgcaa
    13981 gagggcaggc aagctgatta caggtgccga cacgacgatt gactcaatac gaaaaagcaa
    14041 ggcaaagctt gttatttttg caaatgattt ttcaaagagc agtaagaaaa gcgtgcagac
    14101 agccgctgat gaatgcaatg taaaagcatt gacaatgaac cgaagcaaag aggaaatcgg
    14161 atttgctctc ggaaaaatct gcggagttat gacaaccgaa gacaaaggct ttgcagataa
    14221 gcttgaacag cttattgaaa acgaatcggg aggagaattg tatgataaaa tataaggtaa
    14281 aggacgcagc agcagatctc ggagtttcaa acaaggaaat tattgagatt ctcgaaaaac
    14341 attgcggtgt tacaaagaaa acaatgacaa cactcgagga aagcgaactc gatgtgattt
    14401 ttgatgtaat cacaaagaag aacaaggttg aaaactttga cgaatacttt gcggcacgca
    14461 acaacaagct tgacaacgaa agcaagccac agcaggaaga taagcccgca aagcagaatg
    14521 caaaggctga caatcagaag aaaaagaccg ataaaaacga caaaaagcct aacaacaagg
    14581 atgcaaagcc tgcatcaaaa caggaaaaga ttgaagttgc tcaggaaaag agcgttgagg
    14641 agtctgctcc ccgcaagcgc agagtaattg acacccgtgc aacaaatgtt gatgttgagc
    14701 gttacaacca gaagtatgat gaccttgcaa gcgacagctc aaagggcaga agcacggaca
    14761 acattgttaa aaagcagaaa ttcacaaacc gtacccagcg tcaaaagggc agacgacaga
    14821 agcgtgaaac agagcaggag cgtctgaacc gtattgctct tgagcgtaag cagaaaccga
    14881 ttacagttca gattcctgac gaaatcgtag tttcggagct tgctctcaga cttaaggcta
    14941 ccgttgccga ggttgttaaa aaggcattcc ttatgggtac aatggtaaca gcaacagata
    15001 caatcgactt tgacacagcg tcacttatcg ccatggaatt ccacgcaaag gttgaaaagg
    15061 aagttgttgt tacaatcgaa gaacagatta ttgatgacag cgaggacgat gaggcaaatc
    15121 tcgttgagag agctccggtt gttgttgtta tgggtcatgt tgaccacggt aaaacttcaa
    15181 tcctcgacgc tatccgtcac gcaaatgtaa cagcaggcga ggccggcggt atcactcagc
    15241 atatcggtgc ttacagagtt atggtaaacg gcaagcctgt tacattcctc gacacacccg
    15301 gacatgaggc attcacaaca atgcgtgcaa gaggtgctca ggttaccgat attgcaatcc
    15361 tcgttgtagc cgccgatgac
//
