LOCUS       c00070_gnlPro..         3945 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LAIFGBKF_70.
ACCESSION   c00070_gnlPro..
VERSION     c00070_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:25:32
            Original ID  :: gnl|Prokka|LAIFGBKF_70
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3945
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3945
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[390:3618]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      391..3618
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3945
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3945
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..98
                     /locus_tag="ctg70_1"
                     /transl_table=11
                     /translation="YGDNSVWGENTTAENKQSLLDAYNSFSYEKY"
     CDS             complement(391..1431)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_2"
                     /sec_met_domain="IlvN (E-value: 2.4e-84, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.7e-61, bitscore: 194.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKIAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(1492..1983)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_3"
                     /sec_met_domain="ALS_ss_C (E-value: 5.4e-31, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             complement(1996..3618)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.7e-44, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
ORIGIN
        1 gttatggtga taacagcgta tggggtgaga acactaccgc tgagaataag cagtctttgc
       61 ttgacgctta taattctttc tcctatgaga agtattgatt atttaaaaat tgataagttt
      121 taactgcaaa agggttcagc cgtaaaaagc tgaacccttt tattgcacaa caaaaaacgg
      181 ttcagccaaa ttgactgaac ccttaatctg tactatgtta agctcgggaa caagtagttg
      241 taaattatca caaactacct acacgaactg cgggcgaggt actcgcaaaa agggtagctt
      301 gaaaatcaag ctaccctaaa ttcgtactat gttaaagctc gggtgacaga agtttgaata
      361 tatcaaacta acttcacgaa ctaaaaaaca ttagttgttg atgagcttat cttcgtcaga
      421 ccagctgtag agctttctaa cttccttacc gaatacttcg gcaggagctt cggcagcgat
      481 ctttctcata gccttgaagt gaacctgtga accggcatcg ctcatgtcaa ggaggaagtc
      541 cttagcaaat gtaccgtcct gaatgtcaga aagaaccttt ctcatagcct tcttagtatc
      601 ctctgtgatg atctttggac cagtgatgta gtcaccgtac tcagctgtgt tagagattga
      661 atatctcatg cctgcaaaac ctgactgata gataaggtca acgatgagct tcatctcatg
      721 gatacactca aagtaagcgt ttcttgggtc gtaacctgca tcgcaaagtg tttcaaaacc
      781 tgcctgcata agtgcgcaaa caccgccgca aagaacagcc tgttcaccga agaggtctgt
      841 ttctgtttct gttctgaatg ttgtttcaag aacgccggct cttgcaccgc cgataccgag
      901 tgcatatgca agtgcgagat ccttagcctg acctgtagca tcctgttcaa cagcaacgag
      961 gcaaggtaca cccttaccaa cctgatactc tgaacgaact gtgtgacccg gtcccttagg
     1021 agctaccatt gtaacatcaa catcctttgg aggcttgatg caaccgaagt gaatgttaaa
     1081 gccgtgagcg aacataagca tattgcctgc ttcgaggttt ggctcgatgt cgttcttgta
     1141 aagagctgcc tgcttttcat cgttgataag aatcatgatg atgtcagcct gctttgcagc
     1201 ctctgccgat gtatatacct taaagccctg tgcctcagcc tttgcccagc tcttgctgcc
     1261 tttgtaaaga ccgatgatta catcgcaacc tgaatccttg aggttgagag cgtgtgcatg
     1321 accctggctg ccgtaaccaa taatagcaat tttcttaccc ttgagaaggt caaggttaca
     1381 atctgactga tagtagattg gtgctgtcat gttttttgtg tagtctttca tattaaagtc
     1441 ctccttaccg caaacgcggc atataaatta aaatatatgc taactgtaag attaaacgga
     1501 aaccgaagct gtgcctctgt caatggcaac agtacctgtt cttacaatct cacggatacc
     1561 ataaggcttg agtaagtcaa caagcgtgtt gatgcggctt gcacattcgc agtactcaac
     1621 ggtaactgac gaaggggata catcaacgat tttcgcctgc ataatttcaa ccgttttgac
     1681 aatttcggct ctttttgagg cggcgcagtg aaccttgatt aaaacaagct cacggctgat
     1741 aaattcgccc tcgttaagcc tttttacctt gatgacggga atgagcttgt tgagctgttt
     1801 ttcaagctgt tcaacaatgt actcgtcacc gtttgcaacg attgtgattc gggaaaccga
     1861 cgggtcctga gtaacaccta ctgcgagtga gtcgatgtta aaacctcggc gagagaaaag
     1921 tcccgaaatt tttgaaagaa cgcccgcctg attttcaaca agtattgata atgtatactg
     1981 cattttatca cctcattaaa ttgacggagt gtcggggtga acatcgcaaa caagaatgaa
     2041 cggtttttcc gaatcaacaa tacccttgat gatgttttcg gcttccttgt ttgaatgagc
     2101 ctctgcatgg tcaatgccgt aagcatcggc aatcttcaaa aagtcgggat caccgttgag
     2161 aattgttgcg gagtgtctgc cgccgtagtg tttgtcctga agttcacgaa ccattccgag
     2221 tcgtgcgttt ttcataatga tgattttaat tccgagctga ttgcctgcaa tagtcgcaag
     2281 ctcattaagc cccatctgaa aactgccgtc accgcagatt acaataacat cacggtcggg
     2341 tcttgcaaac tttgcaccga ttgcagcggg aattgagtaa cccattgtac ccataccgcc
     2401 tgttgtgagg aacctgccct cacgaatacg gaagttgttt gcacaccaga tttgattttg
     2461 tcctacatcg gcaacgagaa ttgccttcga gcggaacatt gcgctgagat gtccgacaag
     2521 tgttctcggc tcaacaaagc cgtcaaatac gggaggctca cggtaaaggt cttttttcca
     2581 gttctttacg gtttcgctcc acattgttgt aaccttgtaa tcgccgatgc tgtcaagcag
     2641 catattgatg acatttttca tatcgcctac aatcggaatt tctgttttaa cattcttacc
     2701 gatttcagca gggtcaatgt caatgtgaat tacctttgtg ttttcactca tctggtcggg
     2761 agccgcaaca gctctgtcac cgagtcttgc accgcatacg attacaaggt cggcttcgtg
     2821 aagagcacgg ttggcaacag ccttgccgtg agtgccgagc attccaagat aaagttcatg
     2881 ctcgctgggc ataacaccga tgcccatcat agttgaaata acggggatgc ccgtagtttc
     2941 tgcaaacttt tgaagtttaa gcttgatacc cgaactcagc acgccgccgc ctgatacgat
     3001 aacaggacgc ttgcttgcgt tgatggcctc aacagccttt ttaacctgaa ttgcgtgtcc
     3061 cttagtgttc ggcttgtaac cgataatgtt tacgctttcg ggatattcaa aactttcaat
     3121 ttcattttcc tgaatatcaa cgggaatgtc gataagtaca ggaccgggtc tgccggttga
     3181 ggcaatatgg aaagcctctt tgaaaactct cggaaggtct tctgttttgc tgacgagata
     3241 actgtgcttt acaaacggtt cacaagctcc tgtgatgtca gcttcctgaa agacatctct
     3301 gccgagaagg tcggaacgaa cctgacctgt aatggcaaca atcggaatag agtccgtata
     3361 ggcggttgca atacctgtga tgaggttggt tgcaccggga ccggaagttg ccacgcaaac
     3421 accgggacga ttactgcatc ttgcatagcc gcttgccgca tgagcagcgt tctgttcctg
     3481 acgaacaaga atgtgggtaa tgctcgaatc gtaaacttta tcgtaaaatg ggcaaatagc
     3541 cgcaccggga taaccaaaga ctatgtcaac gccctcggct tccaaacatt ttaccataat
     3601 ttcagcaccg ctgatcatta tgttttgtcc ctcctatcct ttttattgtg agcaaaaggt
     3661 gttttgtaac attaaatata cccttttact ttaccgctaa ttatacaata aataccttaa
     3721 aaagtaaaga gcagtattgc ccataaatta aattttttgc aggattttga cagataattt
     3781 gcaaaatgga ttttaattga tttttaccgc ctgtttactg aaaatttaag tcgcttaatt
     3841 ttgtaaagta tagttttgga ttaagattac ttttcccgtc tgtattatca ggagttgtta
     3901 ttatcatcaa attatctttt ccagttcttg tcattgagcc gatat
//
