LOCUS       gnlProkkaLMNOCPCO_289   7704 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMNOCPCO_289.
ACCESSION   gnlProkkaLMNOCPCO_289
VERSION     gnlProkkaLMNOCPCO_289
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:06:29
            Original ID  :: gnl|Prokka|LMNOCPCO_289
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7704
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1791
                     /locus_tag="ctg289_1"
                     /transl_table=11
                     /translation="MQHTGNWTGKTVEFARGCCKIKDARFCITDLPGCYSLLSFSGEEA
                     VTRECLIQNQNDCVVIVVDCGVIERNLSFALQVLSVTKNAVLCLNLCDEAEKNGIKIDC
                     DELSLNLGIPVVKTCATDKKGLDELKKAIYNVCSGKTKCFRVRRNFEGVDILSEKNYKQ
                     NIEKLSQIGNKISSDCVKYEKSELNACTRKLDKILTSKTTGIPIMLAMLGILFWITVVG
                     ANYPSEWLSNLFGFIKEKLYILFDFLHAPDVVTGLLIDGVYTTLSWVVSVMLPPMAIFF
                     PLFSLVEDSGYLPRIAFNLDRYFSKCGAHGKQSLAMAMGLGCNACGVTGCRIIESPKER
                     LIAILTNNFMPCNGRFPTIIALLLMFFAGTTFTLSSSLEVAALLIGIIVFCVFITLVIS
                     KVLSVTILKGEQSGFVLELPPYRKPQILKTIVRSLLDRTLFVLGRAVAVAAPAGAIIWI
                     LANVHISDISLLKYCTDFLDPFGRFIGVDGVIIMAFILGFPANETVIPIIIMSYMASGT
                     LVDYSSYDQLFQLLSMNGWTITTAVCTIILCILHYPCSTTCLTIKKETGSLKWTLVSMA
                     LPTAMGIVLCMITAGVMRLF"
     protocluster    1..7704
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2657:4031]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2658..4031
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..7704
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7704
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(1783..2592)
                     /locus_tag="ctg289_2"
                     /transl_table=11
                     /translation="MNEKIIMLGTGSAMVTDCYNTCFLLKSENDCLLVDAGGGNGILSA
                     IKKSGVAWNSIKTMFITHSHTDHILGAVWVIRQISALINSGKYDGNFNIYCHDECVDSI
                     TAICNHTLAPKFLRNINTKIFINEVKDGEKQNAGSIRLTFFDIFSDKTKQFGFKAVFPS
                     GKVLACLGDEPFNEKCRNFVQNCDYLMCEAFCLYSQKDIFKPYEKFHSTALDAGKLAES
                     LFAKNLILYHTEDETLQTRKRTYTSEARTVFNGNIFVPDDFEVIDLK"
     CDS             complement(2658..4031)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg289_3"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 6.1e-32,
                     bitscore: 98.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.3e-15, bitscore: 46.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.4e-15, bitscore: 46.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.8e-21, bitscore:
                     63.8, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKLNGYNIVLDVYSGSVHAVDDLAYDVIAMYKNATKEQIID
                     EMLSKYADNPEITKEEISDCIDDVKELEEQGKLFTDDKYENLAFDFKKRNTVIKALCLH
                     IAHTCNLNCEYCFASQGKYHGERALMSFEVGKRAIDFLIENSGSRVNLEVDFFGGEPLM
                     NFDVVKQIVAYARSIEKEHNKNFRFTLTTNGMLVDDDVIEFANKECHNVVLSLDGRKEV
                     HDHLRKTVNGKGSYDIIVPKFQEFVKKRGNKGYYVRGTYTHNNTDFTNDIFHMADLGFT
                     ELSMEPVVCAPDDPYALTYDDLPILFEQYEILAKEMLKREKEGRPLTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDEKYKLGDIFNGVSNTKIQDEFKLCNA
                     YARPDCKDCWARLYCSGGCAANAYHATGSITGIYEYGCELFRKRMECAIMMKVAEAEE"
     CDS             complement(4327..5730)
                     /NRPS_PKS="Domain: Aminotran_5 (54-217). E-value: 1.8e-12.
                     Score: 38.6. Matches aSDomain:
                     nrpspksdomains_ctg289_4_Aminotran_5.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg289_4"
                     /sec_met_domain="Aminotran_1_2 (E-value: 6.4e-12, bitscore:
                     33.9, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.5e-09,
                     bitscore: 25.4, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 3.3e-13, bitscore:
                     37.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYDKLKNYSKSGIYPFHMPGHKRTDITEEGIIPYNIDITEIHDF
                     DNLHSPNGVIDEIQKKAAKLYNAKNAFILINGSTGGILSAIRSMTNQGNKILMARNCHK
                     SVYNSAELFNLNVDYIFPDTDSRYNILTSVSPCDIEDKLTKHNDEIRLVIITSPTYEGV
                     VSDIKSISEICHKHGAKLLVDEAHGAHFPFSDNFPDEALNCGADAAVLSLHKTLPSLTQ
                     TALLITNDSELSEILAENLSVFETSSPSYILMSSIEKCLDFCENSKDKFNEYCCNLKTV
                     REKLKNLKYLKIYDKSDTDFDYDIGKIVISTANANISGTKLAEILRNNYQIETEMAYSD
                     YVIAMTSVCDTEKAFDMLSDALISIDSKLSKGADTERVPLKNLYTGKNFNACELYKFNK
                     ETIPFQNSEFRTSAEYIWAYPPGIPLIVPGEIISKELINYIEYLSACKVEIMSTKGGMT
                     DNISVVKKD"
     aSDomain        complement(5080..5568)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg289_4_Aminotran_5.1"
                     /evalue="1.80E-12"
                     /label="ctg289_4_Aminotran_5.1"
                     /locus_tag="ctg289_4"
                     /protein_end="217"
                     /protein_start="54"
                     /score="38.6"
                     /tool="antismash"
                     /translation="IDEIQKKAAKLYNAKNAFILINGSTGGILSAIRSMTNQGNKILMA
                     RNCHKSVYNSAELFNLNVDYIFPDTDSRYNILTSVSPCDIEDKLTKHNDEIRLVIITSP
                     TYEGVVSDIKSISEICHKHGAKLLVDEAHGAHFPFSDNFPDEALNCGADAAVLSLHKTL
                     "
     CDS             complement(5754..7340)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 109.2; E-value:
                     4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg289_5"
                     /transl_table=11
                     /translation="MSSFKEEISKRRTFAIISHPDAGKTTLTEKLLLYGGAINLAGSVK
                     GKRTAKHAVSDWMEIEKQRGISVTSSVLQFKYNGYCINILDTPGHEDFSEDTYRTLMAA
                     DSAVMVIDGSKGVEKQTIKLFKVCVMRNIPIITFINKMDRDAKNSFDLLEDIENVLGIH
                     TYPVNWPIGSGKEFKGVYDRNSKKILAFTANNGQKEVEKKELTLDDPALEDTIGYYHKQ
                     DLFDEIELLDGAGDEFDLEAVRNGQLTPVFFGSALTNFGVEPFLEQFLQLTTPPLPRET
                     VDEKVEPMSDFFSAFVFKIQANMNKAHRDRVAFMRICSGKFEKNMEVFHVQGNKKMRLS
                     QPQQIMAQEREIVDEAYAGDIIGVFDPGIFSIGDTICSPGHKVQFRGIPTFAPEHFALV
                     RQKDTMKRKQFIKGTSQIAQEGAIQIFQELDAGMEEVIVGVVGVLQFDVLKYRLQNEYN
                     CDIIMETLPYEFIRWIVNDDIDPKTLDLASDTKKIQDLKGNHLLLFTSYWSINWALEHN
                     KGLELAEFGTN"
     CDS             7506..7703
                     /locus_tag="ctg289_6"
                     /transl_table=11
                     /translation="MIFPIFSYTFQIEAETCVSASKSFMRFFMSNSIGLYIHIPFCKHK
                     CPYCDFFSGNADENAFDNYVI"
ORIGIN
        1 agacagcaca cgggaaactg gacgggtaaa acagttgagt ttgccagagg ttgttgcaaa
       61 atcaaagacg caagattttg tattacggac ttacccggat gctattccct gctttcattt
      121 tcgggcgaag aggcggtaac aagggagtgc cttatacaaa accaaaatga ctgcgttgta
      181 atagttgttg actgcggagt tattgaaaga aatctttcat ttgcattgca ggtgttatct
      241 gtcacaaaga atgctgttct ttgtcttaat ctttgtgatg aggctgaaaa aaacggtata
      301 aaaatcgact gcgacgagtt atcgctaaac ctcggaatac ctgttgtgaa aacctgtgca
      361 acagacaaaa aaggtttgga tgagttaaaa aaagcgatat ataatgtatg cagcggaaag
      421 acaaaatgtt ttagggtaag aagaaatttt gaaggtgttg atatactatc cgaaaaaaac
      481 tacaaacaga atattgaaaa gctttcgcaa attggtaaca aaatttcaag tgactgcgta
      541 aaatatgaaa aatcagagtt aaatgcttgt acaagaaagc ttgataaaat acttacaagc
      601 aaaaccacgg gaataccgat tatgcttgca atgcttggta tattgttctg gataacagtt
      661 gtcggtgcaa attatccgag cgaatggtta agcaatttgt ttggctttat aaaagagaaa
      721 ctgtatattc tttttgattt tttacacgct cccgatgttg taacggggct tttgattgac
      781 ggagtttata caactctgtc atgggtggta tctgtaatgc tgccgcctat ggctatattc
      841 tttccgttgt tttcgcttgt tgaggattcg ggatatctgc cgagaattgc atttaatctt
      901 gataggtatt tttcaaaatg cggtgcacac ggaaagcaaa gtcttgctat ggcaatgggt
      961 cttggctgta atgcctgcgg agttacgggt tgcagaatca ttgagtcgcc aaaggaacgg
     1021 ctgattgcaa ttcttacaaa taattttatg ccgtgtaacg gacggtttcc cacaatcatt
     1081 gcattactgc tcatgttctt tgcaggtacg acatttacgc taagcagttc gcttgaggta
     1141 gcggcattgt tgattggaat aatagttttc tgtgttttta taacacttgt tatatctaag
     1201 gtactttcag tcacaatatt gaaaggcgaa cagtccggat ttgtgcttga acttccgccg
     1261 tacagaaagc cgcagatttt aaaaactatt gtccgttcgc tgttggacag aactttattt
     1321 gttttaggaa gggctgttgc ggttgccgca ccggcaggtg cgataatctg gattcttgca
     1381 aatgtgcata taagcgatat ttcactttta aaatattgta ctgatttttt agatccgttc
     1441 ggcagattta tcggggttga cggcgttata ataatggcat ttatacttgg atttcctgct
     1501 aatgaaaccg ttattccgat tataattatg tcatatatgg caagcggtac tcttgttgat
     1561 tattcaagct acgatcagct gtttcaactt ctcagtatga acggctggac gattacaacg
     1621 gctgtatgca cgattattct ttgcattctt cattatccgt gttcaacaac ctgtctgaca
     1681 ataaaaaaag aaacaggcag ccttaaatgg acgcttgttt ctatggcatt gcctactgca
     1741 atgggaattg tgctttgtat gattacagca ggtgttatga gattatttta agtcaataac
     1801 ttcgaaatca tcgggaacaa atatatttcc gttaaaaact gttcttgcct ctgaagtata
     1861 tgttcttttg cgtgtttgaa gtgtttcgtc ctcggtgtga tacaggataa gattttttgc
     1921 aaaaagactc tctgcaagtt ttcctgcatc aagtgctgtg ctgtgaaatt tttcgtaagg
     1981 cttaaaaata tctttttgac tgtaaaggca aaaagcttca cacataagat aatcacagtt
     2041 ttgaacaaaa tttctgcatt tttcattgaa cggttcatca ccgagacagg cgagaacttt
     2101 tcctgacgga aagacagcct tgaatccgaa ttgctttgtc ttgtctgaaa atatatcaaa
     2161 gaaagtgagt cggatactgc cggcattttg cttttcaccg tcttttactt cattgatgaa
     2221 aatttttgta ttgatatttc tgagaaattt cggtgcaagt gtgtggttgc aaattgccgt
     2281 gattgaatca acacattcat cgtggcagta aatattaaaa ttaccgtcat atttgcctga
     2341 attaataaga gcgcttattt gccttattac ccacacggca cctaaaatat ggtcggtgtg
     2401 agaatgagta ataaacattg tctttatgct gttccaagct actccggatt tcttaattgc
     2461 ggataaaatt ccgtttccgc cgcctgcgtc aacaagaagg cagtcgtttt cggatttcag
     2521 aagaaaacag gtattataac agtcggtaac catcgcactt cctgtgccga gcataataat
     2581 tttttcgttc atacagcacc tcgaaaatac aggcagatac aagaaaaatg tatctgcctg
     2641 taaattttat tgtaatttta ttcttctgct tctgcaacct tcatcataat ggcacattcc
     2701 attctttttc tgaaaagctc acagccgtat tcgtaaatac ctgtgattga gcctgttgca
     2761 tgataagcgt ttgcggcaca accgccgctg caataaagtc ttgcccagca gtctttgcag
     2821 tcaggacggg cgtatgcgtt acaaagctta aattcgtcct gaattttcgt gtttgaaaca
     2881 ccgttaaaaa tatcgccgag cttgtacttt tcatcgccta caaattgatg acagggatag
     2941 aggtcgcccc aaggtgttac agccatatat tctgtacccg aaccgcaacc cgagattctc
     3001 ttataaatgc acggaccgcc tgtaaggtca atcatataat gatagaaggt gagcggtctg
     3061 ccttcttttt cacgcttgag catttccttt gcaagaattt cgtactgttc aaaaaggata
     3121 ggcaaatcgt catatgtaag tgcatatggg tcatcgggag cacatacaac cggctccatt
     3181 gaaagctctg taaaccccaa atccgccata tggaaaatat cgtttgtgaa gtctgtgtta
     3241 ttatgtgtgt aagtacctct tacatagtaa cccttgttgc ctcttttttt gacaaattcc
     3301 tgaaatttcg gaacgataat gtcataactg cctttgccgt ttacagtttt gcgaagatgg
     3361 tcatgcactt cttttctgcc gtcaaggctg agaactacat tatgacattc tttgtttgca
     3421 aattcaatta catcgtcatc aacaagcata ccgtttgttg taagtgtaaa acggaagttt
     3481 ttgttgtgtt ccttttcaat gcttcttgca taggcaacaa tctgctttac aacatcaaag
     3541 ttcataagag gttctccgcc gaagaagtca acctcaaggt ttactctgct gcctgaattt
     3601 tcaatgagaa agtcaattgc tctcttgccc acttcaaagc tcatcagcgc tctctcgccg
     3661 tggtatttgc cctgacttgc aaagcagtat tcgcagttaa ggttacaggt gtgagcaatg
     3721 tgcagacaaa gtgccttgat tactgtgttt ctctttttaa agtcaaatgc aaggttttcg
     3781 tacttgtcgt ctgtaaagag ctttccctgt tcctcaagct cttttacatc atcaatgcag
     3841 tcagagattt cttcttttgt aatctcagga ttgtctgcat attttgaaag catttcgtcg
     3901 attatctgtt cttttgttgc gtttttgtac attgcaataa catcataagc aaggtcatcg
     3961 actgcgtgta cactgccgct gtaaacatca agaactatgt tgtatccgtt aagtttatac
     4021 tgatgaatca taatatctcc gttagacaaa aggaaagccg ttaacccttt gggaaaacgg
     4081 cgataatcct taataatcaa attaaaatag aattatttct cgctcatgca cttttcgcac
     4141 tgctggttag caacgccgca agatgtctta cacgctgact gacatgaagt ctggcactcg
     4201 ccgcaaccgc ctgtcttaac gctcttcttg aggtcacgag tttcaatagt tttaattctc
     4261 ttcataataa atcaaactcc ttgttagatt ttgttagttt aatattatca cacagccatt
     4321 gatttgtcaa tcttttttaa ctacgcttat gttgtccgtc ataccgcctt ttgttgacat
     4381 aatctcaacc ttgcaggctg aaagatattc aatgtaattt ataagttcct tgcttataat
     4441 ttcaccgggt acgatgaggg gaattccggg tggatatgcc cagatatact cggcagaagt
     4501 tctgaattcc gaattttgaa acggaatagt ttctttgttg aatttgtaca actcgcaggc
     4561 gttgaaattt ttgcctgtgt agagattttt taacggaaca cgctcggtgt cggctccttt
     4621 tgaaagtttg ctgtcaattg aaatcagagc gtctgaaagc atatcaaaag ctttttcagt
     4681 gtcacaaaca gatgtcatgg caattacata gtccgaatat gccatttcgg tttcaatctg
     4741 ataattattt cgcagtattt cggcaagctt tgttcccgaa atatttgcgt tcgctgttga
     4801 aattacaatt ttgccgatat cataatcaaa atcagtatcg cttttatcat aaattttcag
     4861 atattttaga tttttaagtt tttctctgac cgttttaaga ttgcaacaat attcattgaa
     4921 tttatctttg ctgttttcgc agaaatcaag gcatttttca attgaactca ttaaaatata
     4981 tgacggactg cttgtttcaa atacagacaa attttcagca agaatttcag aaagctcgct
     5041 gtcatttgtt atgagcaatg cagtttgagt taatgacggc aaagttttgt gcagactcaa
     5101 tactgctgcg tctgcaccgc agttaagtgc ttcatcggga aaattgtccg aaaacggaaa
     5161 atgcgctccg tgagcttcgt caacaagtaa ttttgctccg tgtttgtgac agatttcgga
     5221 aattgacttt atatccgaaa caactccttc atatgtaggc gaagttatga ttacaagtct
     5281 gatttcatca ttgtgttttg taagtttatc ttctatatcg caaggtgaaa ccgatgtaag
     5341 aatattgtat ctgctgtctg tatcgggaaa aatgtaatcg acattgagat taaacaattc
     5401 tgctgaatta tatacagatt tgtggcagtt acgagccatt aagatcttgt tgccttgatt
     5461 tgtcattgag cgaattgctg aaagtattcc gcctgttgaa ccgttaatca gaatgaaagc
     5521 attttttgca ttgtaaagtt ttgcagcctt tttctgaatt tcgtcaataa ctccatttgg
     5581 cgaatggaga ttgtcaaaat catgaatttc ggttatgtcg atattatacg gtattatacc
     5641 ctcttctgta atgtccgttc ttttgtgtcc gggcatatga aaaggatata tgccgctttt
     5701 tgaataattt ttaagcttgt cgtacagcat atatcctccg atattttaaa tatttagttt
     5761 gtaccgaact cagcgagttc aagtcccttg ttgtgttcaa gcgcccagtt tatgctccag
     5821 tagcttgtaa agagcaaaag atgattgcct ttaagatcct gaattttctt agtatcggac
     5881 gcaaggtcga gagttttcgg atcaatgtca tcgtttacaa tccaacggat aaattcatat
     5941 gggagtgttt ccataatgat atcacagttg tactcgtttt gaagtctgta tttaagaaca
     6001 tcaaactgaa gtacgcctac aacgccaacg ataacttcct ccatacctgc gtcaagctcc
     6061 tggaaaattt gaattgcacc ttcctgtgca atctgacttg tacccttgat gaactgtttg
     6121 cgcttcattg tgtctttctg acggacaagt gcaaagtgtt cgggagcaaa tgtaggaatt
     6181 cccctgaact gtaccttgtg tcccggtgaa cagattgtgt caccgattga gaaaatgccc
     6241 ggatcaaaca caccgatgat gtcgcccgca tatgcctcgt caacaatttc tctttcctga
     6301 gccataatct gttgtggctg tgaaagacgc atttttttgt taccctgaac atggaacact
     6361 tccatattct tttcaaactt gccactgcag atgcgcataa atgcaactct gtcacggtga
     6421 gccttattca tatttgcctg aattttgaaa acaaatgcag agaaaaagtc tgacataggc
     6481 tcaacctttt catcaactgt ttctcttggc agaggtggag ttgtgagctg taagaactgt
     6541 tcaaggaatg gttcaacacc aaagtttgta agagccgaac cgaagaatac aggagtaagc
     6601 tgaccgttgc ggactgcttc aaggtcaaat tcatcgcctg caccgtcaag aagttctatt
     6661 tcatcaaaca aatcctgctt atgatagtag cctattgtat cttcaagggc aggatcgtca
     6721 agcgtaagtt ctttcttttc aacttctttc tgaccgttat tagcggtgaa agcaaggatt
     6781 ttcttggaat ttctgtcata cacacccttg aattccttac ctgaaccgat tggccagttt
     6841 acgggatagg tgtgaattcc gagaacattt tcgatgtctt caagaaggtc aaaagaattt
     6901 tttgcatctc tgtccatctt gttgatgaat gtaatgatag gaatattacg cattacacag
     6961 accttaaaaa gtttgatagt ctgtttctca acaccctttg aaccgtcaat taccattacg
     7021 gcagagtctg ccgccataag tgtacggtag gtatcttccg agaaatcctc atgtcccggt
     7081 gtgtcaagaa tatttatgca ataaccgtta tatttaaact gcaaaaccga tgatgtaaca
     7141 gaaataccac gctgtttttc aatttccatc cagtcggaca cagcatgctt tgcggttctt
     7201 ttgcctttta ccgaacctgc aaggttaatt gctccgccgt agagcaagag cttttccgta
     7261 agtgttgttt tacccgcatc aggatgcgaa ataatcgcaa aggttctgcg cttgctgatt
     7321 tcttctttaa atgaactcat atctttcttc ccttcggagg ttaagtgtat ccacaattct
     7381 atattttact atttttggat ggtatatgtc aataaagaat gaagaaaatg tgagaaaaat
     7441 aattgctaca aaaacttgac aaatttgtaa atatattgta atatattggt acagaaggac
     7501 ttaatgtgat ttttcctatt ttttcatata ccttccaaat cgaggcagaa acttgtgttt
     7561 ctgcctcaaa atcatttatg aggtttttta tgagtaactc tatcggtctt tacattcaca
     7621 taccgttttg taagcacaaa tgtccgtatt gcgatttttt cagcgggaat gcagacgaaa
     7681 acgctttcga taattatgtg attg
//
