LOCUS       c00022_gnlPro..         5390 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMNOCPCO_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:45:12
            Original ID  :: gnl|Prokka|LMNOCPCO_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5390
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5390
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1108:5355]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1109..5355
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..5390
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5390
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(168..965)
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MKKRLKGFFQRLARWLNVREMRQHKVKAGVYIIIRLILVSLLTAG
                     ILNGKWENVMTCVLTLGLLMLPLFIDRKLSVALPSVLETIVVLFVFAANVMGELGAFYE
                     KIPIWDSLLHTVNGFICAGVGFGLTDILNRSERVKLSLSPMFVCLFSFCFSMTVGVVWE
                     FFEFGADMLFEKDMQKDTVITAIHSGLISGKPNVIMHIRDITSTVVNGENLGINGYLDI
                     GLIDTMKDLLVNFVGAVVFDTIGWFYLKGRSAGFLRNFIPVKK"
     CDS             complement(1109..2452)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="HGD-D (E-value: 3.1e-28, bitscore: 87.1,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGNSVMAELKYDKKTGRLLFTKQMKKEYTILMPNMAPIHFKILE
                     KVFNYYGYKSDLLDTTGPEIAQTGLKYVHNDTCYPALLVIGQFINALQSGKYDVHKVAL
                     MITQTGGGCRASNYIFLLRKALKKAGFEFVPVISLSFGMEHNSGFSLTLPLIRRFVGGL
                     VYGDQLMLLSNQTKPYEVNKGESMALVDEWTDKISDMLIQGKGYTLEEIDETLDRITKS
                     FTKIELNKVPKVKVGIVGEIYVKYSKMANNGLEDFLADQDCEVCVPGLMGFASFKVDNR
                     IEDYKMFGGSRVKYKFCSMLLNYLTKLEGLMVDAAEKYGFVPPHRYAHTKELVNGVIGY
                     GSKMGEGWLLTAEMIELADTGYENIVCTQPFGCLPNHINGKGAIRKIKEIRPNANIVTI
                     DYDPGAPKVNQENRIKLMLAVGKEELKKKLEAEKNGEKAESSEKSEKK"
     CDS             complement(2452..5355)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="HGD-D (E-value: 1.2e-18, bitscore: 55.6,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.3e-39, bitscore:
                     123.9, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKLGLDIGSTTIKCVVLDDENKLIYSTYERHYSRITEKIAEILAL
                     VRTRIDGVENASVALSGSAGMGVAESVGVDFIQEVYATRVAANTFIPGTDVIIELGGED
                     AKILFLTNGLEVRMNGTCAGGTGAFIDQMATLLNVKLEDMDELAKQHEKTYTIASRCGV
                     FAKTDIQPLLNQGARKSDIAESIFNAVVSQTVAGLAQGREIEGQIVYLGGPLTFMSELR
                     NCFDRTLGTKGICPENSLYYVACGAALCAEKTIDFDEVIEKVKNYRGSGNFAFNQPLFK
                     NEEEYRKFCDRHAKADVKQKELKGYAGKAYIGMDAGSTTVKGVVLNDDGELLYSKYLPS
                     KGNPVEIMKQFLDEVYEINPEINVVSSAVTGYGEDIVKNAFAVDYGIVETIAHFTAAKY
                     FMPDVEFIIDIGGQDIKCFKIHNGAIDNIFLNEACSSGCGSFLQTFANALGYEIADFAK
                     LGLFAKRPVDLGSRCTVFMNSSVKQAQKDGATIEDISAGLSLSVVKNALYKVIRASSPD
                     ELGKRVVVQGGTFLNDAVLRAFEQEMGVEVVRPNIAGLMGAYGAALYAKKKSKGVGKST
                     ITDKKGLDEFVHEIKVANCGMCNNNCRLTINSFGKGRKFIAGNRCERPITKKAPANDMN
                     MYAYKLNLIDSYKPVEGIRGKLGIPMALNMYELYPFWYRFFTELKFEVFHSPYSTRKLY
                     QRGQQTIPSDTVCFPAKLVHGHIQTLIDMGAETIFYPCLSYNFDEHLGDNHYNCPVVAY
                     YPEVIKNNMKDIRKVHFIKEYFGIHRPNDFPKKAYERLSFHFPDLTLNEVRNAAKLAYQ
                     EQENYRKKVIDKGSEIIAKAEKEGKKIFVLAGRPYHIDPEINHGIDRLISGFDVAIVSE
                     DVISPRVEHFRTHVLNQWTYHARLYAAAKYVTTRKDMELVQLVSFGCGVDAITTDEVRE
                     ILESKNKIYTQIKIDEITNLGAVKIRIRSLLAALEND"
ORIGIN
        1 tcacggcaat gtgactgccc tcttgctaat tgaaaattaa aagtaaaaaa ttgcaggggt
       61 gaaccgtgtt cgcccgttcg tgtgcgatgc acacgattga acgcatagcg ttcaaatatc
      121 atatgcaact catttatata atttgatttt acataaacat tgcgtcatta ttttttaacg
      181 gggataaaat tccgcaaaaa tcctgcactt cttcctttca ggtaaaacca acctatggtg
      241 tcaaaaacta ccgctcctac aaaattaaca agcaaatctt tcattgtatc gatcagaccg
      301 atgtcaaggt aaccgttaat accgagattt tcaccgttca caacggttga tgttatatct
      361 ctgatgtgca ttatcacatt cggcttgccc gaaatcaaac ccgaatgtat tgccgtgatt
      421 acggtgtcct tttgcatatc cttttcaaaa agcatatccg caccaaactc aaaaaactcc
      481 cacacaacac cgactgtcat tgaaaagcag aacgaaaaca ggcacacaaa catgggcgag
      541 aggctcaatt tcacccgctc gcttctgttc aaaatatcgg tcagtccaaa accaacgcct
      601 gcacagataa agccgttcac agtatggagc aatgaatccc atatcggaat cttttcgtag
      661 aacgcaccga gctcacccat aacatttgcc gcaaacacga acagcacaac aatcgtttca
      721 agcacactcg gcaacgctac cgacagcttt cggtcgatga acaacggaag catcaacagt
      781 ccgagcgtta acacgcaggt catgacattc tcccattttc cgtttaaaat gccggcagtc
      841 aaaagtgaca caagtatgag ccttataatg atgtaaacgc ctgccttaac cttgtgctgt
      901 cgcatttcac gcacattcag ccaccgtgca agcctttgaa aaaatccttt aagtcgtttt
      961 ttcataatat cccccgattt ttacacttat tttttcctta aaaacgagat aaacccctgt
     1021 aaatttgtat tagctttttc tgcctgatat taccgcaaaa taaaaaagcc accgccatct
     1081 gcgatgactc ataagcattg atattaaatt actttttctc tgacttctct gacgattcgg
     1141 ctttttcgcc atttttttca gcctcaagct ttttcttgag ttcctctttg ccgacagcaa
     1201 gcatcagctt gatacggttc tcctgattta ccttcggcgc acccggatca tagtcgatgg
     1261 taacgatatt ggcattcggt ctgatttctt taatctttct gattgcgccc ttaccgttga
     1321 tatgattcgg cagacaaccg aaaggctgtg tgcatacgat attctcatag cctgtatcgg
     1381 caagttcaat catctcggct gtcagcaacc aaccctcgcc catcttactg ccgtagccga
     1441 taacaccgtt tacaagctcc tttgtgtgag catatctgtg aggcggaaca aagccgtact
     1501 tttcagcggc atcaaccata agtccctcaa gctttgtgag gtagttaaga agcatcgaac
     1561 agaatttgta tttaactctg cttcctccga acatcttgta gtcctcaata cggttatcaa
     1621 ccttaaatga tgcaaaaccc ataagaccgg gtacgcaaac ctcgcaatcc tgatctgcaa
     1681 gaaagtcctc aagaccgttg ttagccattt tggagtattt tacatagatt tcgccgacaa
     1741 taccgacttt aaccttcggc actttgttaa gctctatttt tgtaaatgac tttgtaattc
     1801 ggtcaagagt ttcgtcaatt tcttcaagag tgtagccctt gccctgtatg agcatatcgg
     1861 aaatcttatc cgtccactca tcaacaagcg ccatactttc gcccttgttc acttcataag
     1921 gctttgtctg atttgaaagc agcattaact ggtcgccgta cacaagaccg ccgacaaatc
     1981 tgcggataag cggaagtgtg agcgaaaagc cgctgttgtg ctccataccg aacgaaagtg
     2041 aaattacggg aacgaactca aagcctgcct ttttgagagc ctttctcaaa aggaaaatgt
     2101 agtttgacgc acgacatccg ccgcctgtct gagtaatcat cagggcaacc ttgtgaacat
     2161 catactttcc gctttgcaga gcattgatga actgacctat aaccagcaaa gccggataac
     2221 aggtatcgtt gtgaacatat ttaagacctg tctgcgcaat ctccggaccc gttgtgtcga
     2281 gcaaatcaga cttatagccg tagtagttga acaccttttc aagtatttta aaatgaatag
     2341 gcgccatatt gggcataaga attgtgtatt cctttttcat ctgctttgta aacagcaaac
     2401 gacctgtttt tttgtcatac ttcaactctg ccataacaga atttcctttc atcaatcgtt
     2461 ttcaagcgca gcaagcaaac tgcggattcg gattttaact gctccgaggt ttgtaatttc
     2521 atctatctta atctgagtgt aaatcttatt tttgctttca agaatttctc ttacctcatc
     2581 ggttgtaatc gcatcaacac cgcagccgaa ggatacaagc tgaacaagct ccatgtcctt
     2641 tcttgttgta acatattttg ccgccgcata aagtcttgcg tggtatgtcc actggttaag
     2701 aacatgagtc cggaaatgtt caactctcgg agaaataaca tcttcgctga cgattgcaac
     2761 atcaaagcct gagataagtc tgtcgattcc gtggttaatt tcgggatcaa tatgatatgg
     2821 tctgcctgca agaacaaaaa tctttttgcc ctctttttca gccttggcaa taatctcgct
     2881 gcccttgtcg ataacctttt ttctgtaatt ttcctgttcc tgatatgcaa gcttagccgc
     2941 atttcttacc tcgttaagag tgaggtcggg gaagtggaac gaaagtcttt cataggcttt
     3001 cttcggaaaa tcgttcgggc ggtgaatacc aaagtattcc tttatgaagt gaaccttgcg
     3061 tatatccttc atattgtttt tgataacctc gggatagtaa gcaacaacag gacagttgta
     3121 atggttatct ccgagatgct cgtcaaaatt ataggaaaga caggggtaga aaattgtttc
     3181 tgcacccata tcaataagag tctgaatgtg accgtgaaca agctttgcag ggaagcaaac
     3241 ggtatcgctc ggaattgtct gctgacctct ctgataaagc tttcttgttg aatacggtga
     3301 gtggaacacc tcaaatttaa gttctgtaaa gaatctgtac cagaacggat aaagctcata
     3361 catattgagc gccataggaa ttccaagctt acctcttatg ccttcaacag gcttgtagga
     3421 atcaatgaga ttcagcttat aggcatacat attcatatcg tttgcaggag ctttctttgt
     3481 gatcggtctt tcacaacggt ttcctgcaat aaactttctg cccttgccga atgaatttat
     3541 tgtaagacgg cagttgttgt tgcacatacc gcagtttgca accttgattt cgtgaacaaa
     3601 ttcatcaagt ccctttttgt cggtaattgt actcttgcca acgccctttg actttttctt
     3661 tgcgtaaaga gccgcaccgt aagcacccat aagtcctgca atgttaggac ggacaacttc
     3721 aacgcccatt tcctgttcaa atgcacgcaa aacagcatcg ttaaggaaag taccgccctg
     3781 aaccacaaca cgcttgccga gttcgtcggg gcttgacgca cgaataacct tgtaaagggc
     3841 attctttaca acgctgagtg aaagacctgc cgagatatct tcaattgttg cgccgtcttt
     3901 ctgagcctgc ttaacgcttg aattcatgaa tacggtacag cgtgagccga ggtcaacggg
     3961 acgctttgca aaaagtccga gctttgcaaa gtcggcaatc tcatatccga gagcgtttgc
     4021 aaaagtctgc aaaaagcttc cgcaacccga tgaacaagcc tcattaagga atatattgtc
     4081 aattgcaccg ttatgtatct taaagcattt gatatcctgt ccgccgatat cgatgataaa
     4141 ttcaacatcg ggcataaagt attttgcggc ggtaaagtgg gcgattgttt caacaatgcc
     4201 gtaatcaacc gcaaatgcgt tctttacaat gtcctcaccg taacctgtta cggcagaaga
     4261 aacaacattt atttcgggat ttatttcgta aacctcgtca aggaattgct tcataatctc
     4321 aacggggttt ccctttgatg gcagatattt tgaatagagc aactcaccgt catcattgag
     4381 gacaacgccc tttacggttg ttgaacctgc gtccattcct atataagcct tgcctgcgta
     4441 accctttagc tccttctgct taacatcagc ctttgcatga cggtcgcaga attttctgta
     4501 ctcctcttcg tttttaaaga ggggctgatt gaacgcaaag ttaccgctgc cacggtagtt
     4561 ctttaccttt tcgataacct cgtcaaaatc aatagtcttt tcggcacaca aagccgcacc
     4621 gcaggcaaca taataaagtg aattttcggg gcagatgccc tttgttccga gcgtgcggtc
     4681 aaagcagttt cgcagttcgc tcataaatgt aagaggtccg ccgagatata caatctgacc
     4741 ttcaatttct ctgccctgtg caagacctgc aacagtctgg cttacaaccg cattgaaaat
     4801 actctctgcg atgtcgctct tcctcgcacc ctgattaagg agcggctgaa tatcggtctt
     4861 tgcaaacaca ccgcatcttg atgcgattgt gtatgtcttt tcgtgctgtt ttgcaagctc
     4921 gtccatatcc tcaagcttaa cattcagaag tgttgccatc tggtcaataa acgcacccgt
     4981 gccgccggcg caggtaccgt tcattcttac ctcaagtccg tttgtgagaa acaatatctt
     5041 tgcatcctca ccgccgagtt caattataac atctgtaccc ggaataaaag tattggcggc
     5101 aactcttgtt gcgtaaacct cctgaataaa atcaacgccg acagactcgg caacacccat
     5161 tccggcagaa cccgaaagag ccaccgaggc attttcaacg ccgtcaatcc ttgtccgtac
     5221 aagtgcaaga atttctgcaa tcttttccgt aattcgggaa taatgccttt catatgtgct
     5281 gtatattaat ttgttttcgt cgtcaagcac aacacatttt attgttgttg agccaatatc
     5341 caatcctaat ttcaacttgt gcctccgaaa tcaatacata gtaatctcat
//
