LOCUS       c00028_gnlPro..         8693 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FIIJNDME_28.
ACCESSION   c00028_gnlPro..
VERSION     c00028_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:21:14
            Original ID  :: gnl|Prokka|FIIJNDME_28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8693
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8693
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3816:7044]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3817..7044
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..8693
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8693
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..2194
                     /locus_tag="ctg28_1"
                     /transl_table=11
                     /translation="SEKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCA
                     HCAGKIEAKIAETDGFEDVSFNFATKLLNFKSEKQNPVSEIQAICDSIENGVTVVDKTP
                     KNDITTKAEPEITKKKINRDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVAT
                     LLSGYKVFIKGAKNILKLRIDETTLMSVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRA
                     VDASRRDIEKLANIRPDTATIIVDGAEQIVPAESVEIGSIIEVKPYERVPLDGIIIKGK
                     TTLDTSALTGESLPVDAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAA
                     QKGNSEKLISRFASVYTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIV
                     ISVPLSYYSGIGAASEVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGS
                     YSADEVLALAAASEKYSAHPIASAIREKANGLELPELSDYSESAGHGTSAVYNGKTIQC
                     GGSKILSDEQKKIANKDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLEGLGVKNTVM
                     LTGDRQQPAENVKNELGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSA
                     SDCGIAMGFGSEAAIEASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVI
                     ILAAFGLAQIWMSVIADTGVSVVCVLIAARLLKKKY"
     CDS             2378..3619
                     /locus_tag="ctg28_2"
                     /transl_table=11
                     /translation="LKKIFLLLVTALFLLSLYGCNTSSSSNNPTEQTTVTNTDDLSLDS
                     DIETTELNHDFEIYNNGKKVDTLNLYGLFKQIDNGFIYSKINKDSPNEMEYYRYYFDKK
                     NSVKLGSIKNWSMQIHDKAYVNNHLCFTASTGDITDEENRTLEFIDIDLNKNKMTTVFS
                     DKGGFPYDTVTGADNLVIITKVLDNGTSLELYDTETQKFKQLKYLEFDDKNSIGETIRK
                     VSIDKSTKTISLLVLDCISQNEASLKIETYDYDMNFLKSYDISNISDDSNELIQGVQVF
                     DFKNNYLFYQNFSITRCIGYIDSDKLKKSDISEDVDDTFSIVSASEDDSDTNLLYKRAE
                     SSSENNYIYLFDTTNKTMKETKFNIEEKGYTIGGISRIGKDNLMIMMSPDNADKKSDLN
                     SRIYFTKLSDLNFQ"
     CDS             3817..5439
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-43, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             5452..5943
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_4"
                     /sec_met_domain="ALS_ss_C (E-value: 8.1e-31, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             6004..7044
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_5"
                     /sec_met_domain="IlvN (E-value: 3.7e-84, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.6e-61, bitscore: 194.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKIAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(7339..8691)
                     /locus_tag="ctg28_6"
                     /transl_table=11
                     /translation="VYYKGRKGWTRMVDTTSTSYIDKDVSSGRNYTYTVRCITSDAKKF
                     TSGYNPTGKSVKYVATPKISKLEVTYDGVKLTWNKVAGAEKYRVYYKDRNGWTKLADTT
                     GTTMLDMNVVSKEFDLSIDDIYYTVRCISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIG
                     AVNNGVEMHWTGDAPKFRVYIKENGSWKRIAETYDNYYVHKGARSGSNTYTVRGVSKDG
                     KKFTTMFNPTGVTYRYKTSDKTRDAYINYMMNHTDEWMPSLGSNHNLSGVMFLDFDFDG
                     VPELVAQKADSNEYSFHSVVYKFEDGKLKRVGNVNDGFAIYYNKTAKKYEVHDLKISLN
                     VDDGYYWSGNSIITYDGENLFANMYSARGVGEESNNNIYYRYFDGNDKNISRAKYNEIN
                     LKQFNNCVDAHMFTQFIATGYGDTSVWGEKTTAENKQSLLDAYNSFSYEKY"
ORIGIN
        1 aagcgaaaag cagaatcctg tttccgaaat tcaggcaatt tgcgacagca ttgaggacgg
       61 tgtaaccgtt gttgacaaaa ctccgaaaac caatctcaaa aaatacacct acactttaga
      121 caatctcaat tgtgctcatt gtgcgggcaa aattgaggct aaaattgcag aaacagacgg
      181 ctttgaggat gtaagcttca attttgcgac aaaacttctc aatttcaaaa gcgaaaagca
      241 gaatcctgtt tccgaaattc aggcaatttg cgacagcatt gagaacggtg taactgttgt
      301 tgacaaaact ccgaaaaatg atatcacaac aaaggcagaa cccgaaatca caaaaaagaa
      361 aatcaaccgt gacacaatct tccttgcaat ttcaattgta cttgctgtag tgtccgaaat
      421 tctccacctt acacttgacg gtgttacggc tgttcattat gttgtactcg cagcgtgttt
      481 tgttgcaaca cttctttcgg gttacaaggt attcatcaag ggtgcaaaaa acattctaaa
      541 gctgagaatt gacgaaacaa cgcttatgtc tgttgcggta attgcggcat tctgtcttgg
      601 cgattttgtt gaggcggcaa tggtaacaat cctcttttct atcggtgaaa tttttgagga
      661 tcgagcagtt gacgcatccc gccgtgacat tgaaaagctt gcaaacattc gtcccgatac
      721 agcaacaatt attgttgacg gtgcggaaca gattgttcct gccgaaagcg ttgaaatcgg
      781 aagtatcatt gaagtcaagc catacgaaag agttccgctt gacggcatta ttattaaagg
      841 taaaacgact ctcgacacat ctgctctcac aggcgaaagc cttcctgttg atgcaggcga
      901 gggcagtgag gtactcagcg gtgcaatcaa cggcagtaac cttattaccg tcaaaaccac
      961 aaaacatttc ggcgacagta ccgcaacaag gattcttcag cttgttgaag atgccgccgc
     1021 tcaaaagggc aacagcgaaa agcttatttc aagatttgcc tctgtttaca caccggttgt
     1081 tgtactcatt gcagttgcaa tcgcagtaat tcctccgctt tgcggactcg gagcattcag
     1141 cgaatggcta taccgtgcgc ttgtttgtct tgtagcgtca tgtccgtgtg ctattgttat
     1201 ttccgtacct ctctcctact attcgggtat cggtgcggca tccgaagtcg gtgtactcat
     1261 caagggcgga aaatatattg aggctcttgc aaaagcagac acatttgtat tcgataaaac
     1321 aggcacgctc acaagcggca agctcagcgt aaacaaggtt aatactgttg gttcatacag
     1381 tgctgacgaa gttcttgctc ttgccgctgc aagcgaaaag tattccgctc atccgattgc
     1441 ctccgcaatc agagaaaagg caaacggtct tgaactcccc gagctttccg actacagcga
     1501 aagtgccggt cacggaacaa gtgcagttta taacggcaaa actattcagt gcggcggttc
     1561 aaagattctt tcggacgaac agaagaagat tgcaaataaa gacgattctg ttttcgtaat
     1621 ttatgacggt cagcttatcg gttcgctcaa tgtcagcgat acggtaagac ctgaggcaaa
     1681 agaggttatc tcacagcttg aagggctcgg tgtcaagaac acggtaatgc tcacaggcga
     1741 cagacaacag cctgccgaaa atgttaaaaa tgaactcgga ctttccgaat gtcacgcaga
     1801 gcttctccct gctcaaaagc ttgagctttt caagggcttg aaatcaaaat ccaagggcgc
     1861 ttgctttgtg ggtgacggca tcaatgatgc ccctgttctt tcggcaagcg actgcggtat
     1921 cgcaatggga ttcggcagtg aagccgctat tgaagcatca gacgcagttc tcgcatcagg
     1981 cacactcaaa cagcttccaa aggcaattaa aattgcaaga agtgttatca acacagtcaa
     2041 gggcaacatc atcttcgccc tctcaatcaa ggctcttgta atcatcctcg ccgcattcgg
     2101 tcttgcacaa atctggatgt ctgttatcgc cgacacaggc gtcagcgtag tctgcgtcct
     2161 cattgccgca agactcctca aaaagaaata ttgatttttt ttattatgat aaagcaccgt
     2221 gagctttcac aagtttcacg gtgctttcat ttgccaaaat ttttctaaat ataatcttat
     2281 attatagtat ttttaaatca ttgactttta taattatgta aattataata tttttgtcag
     2341 cgcttgtaac tgataaataa acttcggaga gattaatttg aaaaagatat ttttattatt
     2401 agtaaccgct ttatttttac tttcattata cgggtgtaac acttcttcat caagcaataa
     2461 ccccactgaa caaacaaccg taacgaatac agatgattta tctcttgatt cagatattga
     2521 aacaacagaa ttaaatcatg attttgaaat ttacaataac ggcaaaaagg tggatacttt
     2581 aaatctttac ggcttattta aacaaattga taacggcttc atatattcaa aaatcaataa
     2641 agactctcca aatgaaatgg aatattacag atattatttt gataaaaaaa acagtgtaaa
     2701 acttggttca ataaaaaact ggtctatgca aattcacgat aaagcttatg taaataatca
     2761 cctttgcttt acggcaagca cgggtgacat tacagatgaa gaaaacagaa cccttgaatt
     2821 tattgatatc gaccttaata aaaacaaaat gacgactgta ttttctgaca aaggcggatt
     2881 tccatatgac actgttacag gagcagacaa tcttgtcata atcacaaaag tgctagacaa
     2941 cggtacttct ttggaactgt atgataccga aactcaaaaa ttcaagcaat taaaatattt
     3001 agagtttgat gataaaaaca gtatcgggga aactataaga aaagtttcaa ttgacaaaag
     3061 tacaaaaaca atctctcttt tggttttgga ttgcatttca cagaacgaag cttctttaaa
     3121 aatagaaact tatgactatg atatgaattt tctcaaaagc tatgatatat ccaacatttc
     3181 agatgattca aacgaattaa ttcagggcgt acaggttttt gattttaaaa acaattatct
     3241 attctatcaa aatttcagca taacaagatg tataggatat atagacagcg ataagctgaa
     3301 aaaatccgac atatcagaag atgtagatga tactttttca atagtatccg catctgaaga
     3361 tgacagtgat acaaatttat tgtataagag ggcggaatca agttcagaaa ataactacat
     3421 atatcttttt gatacaacca acaaaacaat gaaagaaaca aaatttaata ttgaagaaaa
     3481 agggtacact ataggcggta tatcacggat aggaaaagat aatttgatga taatgatgtc
     3541 ccctgataat gcagacaaaa aaagtgacct taattcaaga atatacttta caaaattaag
     3601 cgacttaaat tttcagtaaa caggcggtaa aaatcaatta aaattcattt tgcaaattat
     3661 ctgtcaaaat cctgcaaaaa atttaattta tgggcaatac tgctctttac tttttaaggt
     3721 atttattgta taattagcgg taaagcaaaa aggtatattt attgttacaa aacacctttt
     3781 gctcacaata aataaggata ggagggacaa aacataatga tcagcggtgc tgaaattatg
     3841 gtaaaatgtt tggaagccga gggcgttgac atagtctttg gttatcccgg tgcggctatc
     3901 tgcccatttt acgataaagt ttacgattcg agcattaccc acattcttgt tcgtcaggaa
     3961 cagaacgctg ctcatgcggc aagcggctat gcaagatgca gtaatcgtcc cggtgtttgc
     4021 gtggcaactt ccggtcccgg tgcaaccaac ctcatcacag gcattgcaac cgcctatacg
     4081 gactctattc cgattgttgc cattacaggt caggttcgtt ccgaccttct cggcagagat
     4141 gtctttcagg aagctgacat cacgggagct tgtgaaccgt ttgtaaagca cagttatctc
     4201 gtcagcaaaa cagaagacct tccgagagtt ttcaaagagg ctttccatat tgcctcaacc
     4261 ggcagacccg gtcctgtact tatcgacatt cccgttgata ttcaggaaaa tgaaattgaa
     4321 agttttgaat atcccgaaag cgtaaacatc atcggttaca agccgaacac taagggacac
     4381 gcaattcagg ttaaaaaggc tgttgaggcc atcaacgcaa gcaagcgtcc tgttatcgta
     4441 tcaggcggcg gcgtactaag ttcgggtatc aagcttaaac ttcaaaaatt tgcagaaact
     4501 acgggtatcc ccgttatttc aactatgatg ggcatcggtg ttatgcccag cgagcatgag
     4561 ctttatctcg gaatgctcgg cactcacggc aaggctgttg ccaaccgtgc tcttcacgaa
     4621 gccgaccttg taatcgtatg cggtgcaaga ctcggtgaca gagctgttgc ggctcccgac
     4681 cagatgagtg aaaacacaaa ggtaattcac attgacattg accctgctga aatcggtaag
     4741 aatgttaaaa cagaaattcc gattgtaggc gatatgaaaa atgtcatcaa tatgctgctt
     4801 gacagcatcg gcgattacaa ggttacaaca atgtggagcg aaaccgtaaa gaactggaaa
     4861 aaagaccttt accgtgagcc tcccgtattt gacggctttg ttgagccgag aacacttgtc
     4921 ggtcatctca gtgcaatgtt ccgctcaaag gcaattctcg ttgccgatgt aggacaaaat
     4981 caaatctggt gtgcaaacaa cttccgtatt cgtgagggca gattcctcac aacaggcggt
     5041 atgggtacaa tggggtactc aattcccgct gcaatcggtg caaagtttgc aagacccgac
     5101 cgtgatgtta ttgtaatctg cggtgacggc agttttcaga tggggcttaa tgagcttgcg
     5161 actattgcag gcaatcagct cggaattaaa atcatcatta tgaaaaacgc acgactcgga
     5221 atggttcgtg aacttcagga caaacactac ggcggcagac actccgcaac aattctcaac
     5281 ggtgatcccg acttcttgaa gattgccgat gcttacggca ttgaccatgc agaggctcat
     5341 tcaaacaagg aagctgaaaa catcatcaag ggtattgttg attcggaaaa accgttcatt
     5401 cttgtttgcg atgttcaccc cgacactccg tcaatttaat gaggtgataa aatgcagtat
     5461 acattatcaa tacttgttga aaatcaggcg ggcgttcttt caaagatttc gggacttttc
     5521 tctcgtcgag gttttaacat cgactcactt gcagtaggtg ttactcagga cccgtcggtt
     5581 tcccgaatca caatcgttgc aaacggtgac gagtacattg ttgaacagct tgaaaaacag
     5641 ctcaacaagc tcattcccgt tattaaggta aaaaggctta acgagggcga atttatcagc
     5701 cgtgagcttg ttttaatcaa ggttcactgc gccgcctcaa aaagagccga aattgtcaaa
     5761 acggttgaaa ttatgcaggc gaaaatcgtt gatgtatccc cttcgtcagt taccgttgag
     5821 tactgcgaat gtgcaagccg catcaacacg cttgttgact tactcaagcc ttatggtatc
     5881 cgtgagattg taagaacagg tactgttgcc attgacagag gcacagcttc ggtttccgtt
     5941 taatcttaca gttagcatat attttaattt atatgccgcg tttgcggtaa ggaggacttt
     6001 aatatgaaag actacacaaa aaacatgaca gcaccaatct actatcagtc agattgtaac
     6061 cttgaccttc tcaagggtaa gaaaattgct attatcggtt acggcagcca gggtcatgca
     6121 cacgctctca acctcaagga ttcaggttgc gatgtaatca tcggtcttta caaaggcagc
     6181 aagagctggg caaaggctga ggcacagggc tttaaggtat atacatcggc agaggctgca
     6241 aagcaggctg acatcatcat gattcttatc aacgatgaaa agcaggcagc tctttacaag
     6301 aacgacatcg agccaaacct cgaagcaggc aatatgctta tgttcgctca cggctttaac
     6361 attcacttcg gttgcatcaa gcctccaaag gatgttgatg ttacaatggt agctcctaag
     6421 ggaccgggtc acacagttcg ttcagagtat caggttggta agggtgtacc ttgcctcgtt
     6481 gctgttgagc aggatgctac aggtcaggct aaggatctcg cacttgcata tgcactcggt
     6541 atcggcggtg caagagccgg cgttcttgaa acaacattca gaacagaaac agaaacagac
     6601 ctcttcggtg aacaggctgt tctttgcggc ggtgtttgtg cacttatgca ggcaggtttt
     6661 gaaacacttt gcgatgccgg ttatgaccca agaaacgctt actttgagtg tatccatgag
     6721 atgaagctca tcgttgacct tatctatcag tcaggttttg caggtatgag atattcaatc
     6781 tctaacacag ctgagtacgg tgactacatc acaggtccaa agatcatcac agaggatact
     6841 aagaaggcta tgagaaaggt tctttctgac attcaggatg gtacatttgc taaggacttc
     6901 ctccttgaca tgagcgatgc cggttcacag gttcacttca aggctatgag gaagatcgct
     6961 gccgaagctc ctgccgaagt attcggtaag gaagttagaa agctctacag ctggtctgac
     7021 gaagataagc tcatcaacaa ctaatgtttt ttagttcgtg aagttagttt gatatattca
     7081 aatttctgtc acccgagcat tacatagtac gaatttaggg tagcttgaaa aaattcaagc
     7141 tacccttttt gcgagtacct cgctcgtagt tcgtgtaggt agtttgtgat aatttacaac
     7201 tacttattcc cgagcttaat atagtacaga ttaacggttc agtcaatttg gctgaaccgt
     7261 tttttgttgt gcaataaaag ggttcagctt tttacggctg aacccttttg cagttaaaac
     7321 ttatcaattt ttaaataatc aatacttctc ataggagaaa gaattataag cgtcaagcaa
     7381 agactgctta ttctcagcgg tagttttctc accccatacg ctggtatcac cataacctgt
     7441 cgcaataaat tgggtaaaca tatgtgcatc cacgcaatta ttaaactgtt taaggttaat
     7501 ttcgttatat tttgcccgtg aaatattttt gtcattaccg tcaaaatatc tataataaat
     7561 attattattt gattcttcgc ctacacctct tgccgaatac atatttgcaa aaagattctc
     7621 tccgtcgtat gtgattattg aattacccga ccaatagtaa ccgtcatcta catttaaaga
     7681 tatctttagg tcgtgaacct catacttttt ggcagtttta ttatagtata tcgcaaaacc
     7741 gtcgttaaca tttcccactc tttttaactt accgtcttca aatttgtaaa caacggaatg
     7801 gaaactatac tcattggaat cagccttttg tgcaacaagt tccggaactc cgtcaaagtc
     7861 gaaatccaaa aacataacac ctgacaaatt gtgattactt cccaagcttg gcatccattc
     7921 atcggtatga ttcatcatat agttgatata agcgtccctt gttttatcgg atgtcttata
     7981 tctgtatgtt acaccggttg ggttaaacat cgtcgtaaac tttttaccgt cttttgaaac
     8041 acctcttacc gtataagtgt tactgccgga ccttgcaccc ttgtgaacat aatagttgtc
     8101 ataagtttct gctatcctct tccaagaacc gttttcttta atataaacac ggaactttgg
     8161 cgcatctccc gtccaatgca tttcaacacc gttgtttact gcaccaatgc tgtaaatttc
     8221 gggacaatcc tgatgatcgc caataggcgt accctttgaa tcgtagccgc ttgtaaaact
     8281 cttagcatcc ttgctgatac aacgaaccgt gtaataaata tcatcaatgc ttaaatcaaa
     8341 ttcctttgaa acaacattca tatcaagcat agtcgtgcct gttgtatcgg caagctttgt
     8401 ccaaccgttt ctgtccttgt agtacacacg atacttctct gcacctgcaa ccttgttcca
     8461 tgtcagcttt acgccgtcat atgtgacctc aagttttgaa attttcggtg tggcaacata
     8521 ttttaccgac ttgcctgtcg ggttataacc gcttgtgaat ttctttgcat ctgatgtaat
     8581 acatcttaca gtatatgtgt aatttctgcc ggacgaaaca tccttgtcga tatatgaggt
     8641 tgaagttgta tcaaccattc gtgtccaacc tttacgaccc ttgtagtaaa ctc
//
