LOCUS       c00035_gnlPro..        15267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JBKGAOIE_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:25:44
            Original ID  :: gnl|Prokka|JBKGAOIE_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 9083
            Orig. end    :: 24350
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15267
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[19083:22554]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13471
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15267
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15267
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1093..1611
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQM
                     LVPGFEQLSSQSNAGFILYKVLKTGESKEPIYYTSKVECYYKGTFIDGTVFDDKSFEAG
                     APAELTVSEMVDGFATALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTLIFD
                     LEVTRIVKE"
     CDS             complement(1949..2743)
                     /locus_tag="ctg35_13"
                     /transl_table=11
                     /translation="MQEHPITTSILHKGLGSLLLLLAIAIQCALLTLYGDLPLSITLVD
                     SLLSIALFAVAGYYLWYVQCTLHIMQARVAFAVLVQIACIAGCSILLQIFGLEDWEEFS
                     ITIPFRFLFGLMAWIILSQWYASRERKSEAEPIVRQMEEKTAPPPTTVPEEILDRISVK
                     DGARIHIIPIKEIFYLQACGDYVTLFTTSGQHVKEQTMKYFERSLPSPEFVRIHRSYIV
                     NTEQILRVELFGKETYQVRLKDGTYLRASSAGYKLLKERLSL"
     CDS             complement(2751..3518)
                     /locus_tag="ctg35_14"
                     /transl_table=11
                     /translation="MDMKDYDINFKEKRTNGYLIATLFIIVGILFLLRNLGMIDPSLFD
                     LLVSWPMLLVVSGIFTIFHRNPVGGMLLVGVGVYFLFPQLNWITNDFLRVYWPLGLILL
                     GLVIMLKRKDSIRTKKHKRPFNHPPFGHRKPNDEINYETDNGFVSVDTTFNSVRHIVLD
                     PVFKGADIDVSFGNVILDLKKTTLEADETIINIDSSFSGVVIYVPKGWLVRLKVGSFLA
                     GCQDMRELTEATDMTHTLYICGDLSFSGLELRD"
     CDS             3806..6895
                     /locus_tag="ctg35_15"
                     /transl_table=11
                     /translation="LILCLIAGMPTPAYGSSSYPVKEESYVLVINSYVDGERWSGNLLN
                     MISKFATPEEYTLRIDHISVMLVDTPEKLKEKQEVFFEANKKKPDGIIYLGVNGWAFMR
                     DKIREKWGDIPTLVCSETGEMAENECYFNQRHSSDRVIPLQEAVKGYNATGLVIPYYVK
                     GSIDLVKELIPGLKRLIFISDRRYVSTWLRDEMEKHMETSFPEGKVDFYTEGSCSMDSL
                     LAVLSEKDPHRATAVMYYSWITEKPFLNHSLLYSTLYQGINGISRHPVFSLYDMGVEEG
                     YTIGGYYNSAKTIETALIPLLQQVYNGEDMGKIPVSTVNDPHKYLNYASLISAISNEDN
                     FPRDAIYLNAPPSFLEKYWMQLLGFLIFFLVVVFLAWHYVYRSKQKMKEVELRLLSRYR
                     DLFNNMPLPYIRQRLIREGTQIDVQVLDVNHAFEEKIAPKDFVVNKRGKEIANLIGGSY
                     PLLLSAVPTVLESGKSFTYEYYFEPTGLYYTIIIMPTSEENVVDAFFIDITDIHKFQTH
                     LKAMNHKLAMALEAADLLPWRYNLAEEKIIYESKVHPGDNIETAEVHTHEVSLKEYFSK
                     IHPSFRACVEKAFDDLCNGKIKKVRKEYCLERLIPGEDRHEWEEIQVMVEYDASGKPKA
                     LIGSTISITERKQLEHDLRMARDKAEESNKLKSAFLANMSHEIRTPLNAIVGFSNILAS
                     TDNLEDKKEFADIIENNNSLLLQLINDILDLSKIEAGTLEFTYDYVDINAVLRDLEQSA
                     HLKNKNPDVQISFKDYLEPCVIYTDRNRLSQLMINLLNNAMKFTQAGLISFGYKLRDDN
                     TLWFYVEDTGCGIPENKRKDIFGRFVKLNTFAQGTGLGLSICEMIVTQMKGTIGVDSME
                     GKGSKFWFTLPFQPKKELFPSEEQKPVTLEKIARSEVTILIAEDNSSNYRLFESILKPE
                     YKLIHAWNGKEAVELFYQHKPQLILMDIKMPVMDGYEATAEIRKVSASVPIIAVTAYAF
                     AQDEQRIINSGFDAYTAKPINGKILKDKISTLLTHRIILM"
     CDS             complement(6866..6964)
                     /locus_tag="ctg35_16"
                     /transl_table=11
                     /translation="LVRACRETGFNCFIRSASRKALRLHQNNPMRQ"
     CDS             complement(7101..8333)
                     /locus_tag="ctg35_17"
                     /transl_table=11
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHEVTINLPQIFEETVKP
                     YGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTN
                     SEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNF
                     MVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNIDPDWTFKWSIGGYCFND
                     TFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIGSG
                     WAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQLITPLII
                     DQPYWSYRIHQLGLGPEGLKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEMIQKEGGI
                     KNICDSIERFQ"
     CDS             complement(8367..9578)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_18"
                     /sec_met_domain="Radical_SAM (E-value: 1.5e-16, bitscore:
                     51.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPDRIVEWVKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKALETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQIEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRKPITRFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKQEIVAIGHGYKANCW
                     CTHGCWITSSIIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_19"
                     /sec_met_domain="Fer2_3 (E-value: 2.6e-26, bitscore: 82.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 5.1e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.5e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDISVTLKVWRQRGPKEKGQFETYKIEKINQSVSFLEMLDILN
                     EQLVNEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFHDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKKDADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(10787..12655)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.7; E-value:
                     9.9e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_20"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.7e-60, bitscore:
                     194.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.8e-38,
                     bitscore: 122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVNPANKRRLDVIVVGTGLAGASAAASLAEMGFNVLNFCIQDSPR
                     RAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKGGDYRAREANVYRLAEVSNSIIDQCV
                     AQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQTGQQLLLGAYSALSRQIGLGKVKMYT
                     RHEMLDVVKVDGRARGIIARNLITGKIERYAAHAVVVATGGYVNTFFLSTNAMASNGSA
                     AWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKLTLMSESLRNDGRIWVPKKLEDAKAL
                     QAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDVASRAAKERCDAGFGVNSTGLAVFLD
                     FSDAINRLGKEVVKQKYGNLFDMYEEITNDNPYETPMMIYPALHYSMGGLWVDYELMTS
                     IPGLFAIGEANFSDHGANRLGASALMQGLADGYFVLPYTIQNYLSDQIQVPRFSTDLPE
                     FVEAEKAIKDRIQKLMNVKGKETVDTIHRKLGHIMWEHIGMARDAKGLQEAIQMLKDLK
                     KEFWSNVFIPGNADNLNTELEKALRVADFIEIGTLMAHDALDRAESCGGHFRTEHQTEE
                     GEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNYEFVVPQTRNYKK"
     CDS             complement(12779..13471)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_21"
                     /sec_met_domain="SucD_FumR (E-value: 2.4e-74, bitscore:
                     239.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAV
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             13560..13664
                     /locus_tag="ctg35_22"
                     /transl_table=11
                     /translation="LRKRLKKYFCINGRGQGMCPDTWNNAEGKGFPYE"
     CDS             13657..15072
                     /locus_tag="ctg35_23"
                     /transl_table=11
                     /translation="MNNLYTFAYMRKDLNGSRHFSIGIKFTILLFTIVILVLVLFSYRS
                     DKHGNLFWQVEKLIPHHPDSALVLLDKVRDINGLSLREKARYCLLWTESRDEAGLRHTS
                     DSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPSLALECYLRALEYEGENWDYEF
                     WGRLYNQMGMLYAEQELYGKAMSFLRKASAQYQLLNDAAGQDRILTEVKKYEMLRDSIG
                     SLSARESIYQITSRYDVRPIREDLSKKELMLLQRGQERYLYAFIIGIILFICFLLYRRW
                     RNTQENALRREEALRRSIASQQQRMREEKEENERQITLLEKRITKIKEEKDQELMLVSL
                     QLEKQRLEICNESILNKESKHLLSVAILRKSEVYEKFHDRDAGKIISEDWELLEVLLNK
                     AYDDFTLRLKKLYPVISDTELKACMLTKIGVPANQITRVLKYNSSVLRPRLFRKIFKKE
                     GSTEAFVEFISNF"
ORIGIN
        1 ttcatgagcg ttatagtaag gcgatgaacg agtctaactt cgaggatctt cgccaattga
       61 tcttggattg cgagatcgtt tgcccgattt ccggaactcg taactggacg gaggttcgcc
      121 agtttaactt aatgttctct acggatatgg gttctaccgc tgatggagcg actaagattt
      181 atcttcgtcc ggagacggct caaggtattt tcgtgaactt cttgaatgtg cagaagactg
      241 gccgtatgaa gatcccgttc ggtatcgccc agatcggtaa ggcgttccgt aatgagatcg
      301 tggctcgtca gtttatcttc cgtatgcgcg agttcgagca aatggagatg caattcttcg
      361 ttcgtccggg tgaggagatc gagtggttca agaaatggaa gtctactcgc ttaaaatggc
      421 atcaagctct tggcttggga gatcagaagt atcgttatca cgatcatgag aagttggctc
      481 actacgctaa cgccgctacg gatatcgagt tcgagatgcc gttcggattc aaggaagtgg
      541 agggtataca tagccgtacg aatttcgact tgagtcagca tgagaagttt tccggtaaaa
      601 agatccaata tttcgatccg gagttgaacc agagttacac tccgtatgta atcgagacct
      661 cgatcggtgt agaccgtgtg ttcttgagca tcatggcggg ttcttactgc gaggagacgt
      721 tggcgaatgg cgagagccgt gtggtattga agttgcccgc agccttggct ccgatcaagt
      781 tggccgtatt gccattggtg aagaaagatg gcctgcccga gaaagctgag gagattataa
      841 atatgttgcg tttcgacttc cgttgccaat acgacgagaa ggattctatt ggtaagcgtt
      901 atcgccgtca agatgcgatc ggtaccccgt attgtattac ggtagaccat gacaccttga
      961 aggataattg cgtaacgatc cgtttccgtg acacgatgga gcaagagcgc gtaagcatcg
     1021 ataagcttca cgatattatc acggagaagg tgagcatgaa gaatttattg aaaaaggtaa
     1081 tagagtaaac gaatgaagaa gtactggcat atcgcgttga tgttgttttg cgtgctcatg
     1141 atcacctctt gtggggatga tgatgaggca ctagaggtgg atgaggtttg gaaggtccag
     1201 aatgaggagg cttttcaagc ccagatgctg gttccgggtt tcgagcaatt gagttctcaa
     1261 agtaatgccg gatttatcct ttacaaggtc ttgaagacag gagagagtaa ggagccgatt
     1321 tattatacga gcaaggtgga atgttattat aaagggacgt ttattgatgg aacggttttt
     1381 gatgataaat cgtttgaggc aggtgcccct gccgagctta ctgtttctga gatggtagat
     1441 ggttttgcta cagcgttaca gaatatgcac ccaggagatc gttgggagat ttggattcct
     1501 caacagatgg gatacggttc ggctggaagg agtgcttcgg gaagtgtcat aataaagcct
     1561 tatacgactt tgatctttga tttggaagtt acaaggattg tcaaagagta ggttctttca
     1621 ttaagaataa ttacggccgc ctctttttag gggtggccgt ttttttatag ttatatgtaa
     1681 atctagggaa gcaaacctct ataaacaatt aaagcctgtc tcacgacaag ccctaaccaa
     1741 actttgttaa ccttaaatct aatactatta tgaaaaaacc acgatgcaaa gatacgttcg
     1801 tcaagaccat ttgtcaagtc ttttgcaact aatatatgtt aagtaacatg tcggtacttg
     1861 ctaaaaagtg ttacacaaca taaagctcta tatattacaa tcaaaatctt ctaattttaa
     1921 cgatgattag atccctttca taggactgct aaagggaaag acgttctttg agtagcttat
     1981 agccagcgct actggcacga agataggttc catcctttaa tcgtacttga taggtttctt
     2041 ttccgaatag ttctactcgc aatatctgtt ccgtattaac gatataagag cggtgtatac
     2101 gaacgaactc cggagaagga aggcttcgct cgaaatactt catggtttgc tcctttacgt
     2161 gctgaccgga agtggtgaat aaggtcacat agtcgccaca tgcttgcaaa tagaatatct
     2221 cttttatcgg gatgatatga atacgtgccc cgtcttttac ggatatacga tctagaatct
     2281 cctccggaac ggtagtcggg ggaggtgccg tcttttcctc catttgtctc acgataggtt
     2341 ccgcctcact ctttctttcc cgactggcat accattggga tagaatgatc catgccatta
     2401 ggccgaacag gaatcgaaaa ggaatcgtga tcgagaattc ctcccaatct tccaatccga
     2461 atatttgtag caagatcgag catccggcta tgcaagcgat ttgtacgagt acggcgaaag
     2521 ccactcgtgc ttgcatgata tgtaacgtac attgtacata ccaaagataa tatcccgcta
     2581 cggcgaacaa tgcgatggaa agtaggctat cgaccaaagt gatgctcaac ggaagatcgc
     2641 cataaagagt taataatgcg cattggatcg ctatggctaa aagtagtaat aggcttccca
     2701 gccctttatg taatatggat gttgtaatag gatgttcttg catgatgagt ttagtctctt
     2761 agttcaaggc cgctgaacga caagtctcca catatgtata gtgtatgcgt catgtcggtt
     2821 gcttctgtca gttccctcat atcttggcat ccagccaaga aagaaccaac ctttagacga
     2881 accagccatc ctttaggaac gtatattact acgccgctga aggagctatc tatgtttatg
     2941 atggtttcat cagcctctaa tgttgttttt ttaagatcaa gaatcacgtt gccgaaagat
     3001 acgtctatgt ccgccccctt gaatacgggg tccagtacga tgtgccttac cgagttgaaa
     3061 gtggtgtcaa ccgatacgaa accgttatct gtctcgtagt tgatctcatc gttaggcttt
     3121 ctgtgcccga aagggggatg gttaaaggga cgtttatgct ttttcgtgcg gatagaatct
     3181 ttccgcttca gcatgatgac caatcctaac aggattaatc ctaacggcca atatacacgt
     3241 aaaaaatcgt tcgtgatcca atttaactgc gggaaaagga aatagactcc cacgcccacg
     3301 aggagcatac ctcctaccgg attacggtgg aaaatcgtaa agatgcccga cacgacaagc
     3361 agcatcggcc aagatacaag caagtcaaat aaggatggat ctatcattcc tagattccgc
     3421 agtaaaaata atataccgac aatgataaat aaggtagcga tcagataccc gtttgtcctc
     3481 ttctctttaa aattgatgtc ataatctttc atatccataa gttcaatttt tttgtttttt
     3541 atcaaatgta cgggttcgtc attctataca caagtaaata ccgctgattt ctatacgagt
     3601 atcggtaaat aaccgaataa tcccgattaa aaaagccttt agtttgtaag aaacgtgaat
     3661 ttgacaccaa aacttgataa aaaaactagt ttgataagat tagttgataa ttaaggaata
     3721 tctttgtctt tacaactgca atagaggaat gtagggaatg atacgaaata ttataaattt
     3781 aaaggcaata atactttatt ttcgattgat tttatgcttg atagccggta tgccgactcc
     3841 ggcttatggg agttcttcat atccggtcaa ggaggaatcg tatgtattgg tgataaattc
     3901 atatgtggat ggcgaacgtt ggtctggtaa tttattaaac atgatctcga agttcgctac
     3961 cccggaggag tacactctcc ggatagatca tataagcgtg atgttggttg atacgccaga
     4021 gaaattaaaa gagaaacaag aggtcttctt tgaagctaac aagaagaagc cggatggaat
     4081 tatctactta ggcgtaaatg gatgggcttt tatgcgggat aagatccggg agaaatgggg
     4141 ggatattccc actctggtct gttcggagac gggggaaatg gcagaaaatg aatgttattt
     4201 taatcagcgg cattcctctg atagggtgat tcctttacaa gaggcggtta aggggtataa
     4261 cgctacggga ttggttatcc cttattatgt taaaggttcg atcgacttgg tgaaggaatt
     4321 aatcccgggt ttgaaacgtc tgattttcat atccgacaga cgttatgttt ccacatggct
     4381 ccgggatgag atggagaaac atatggaaac ttctttccct gaggggaaag tggattttta
     4441 tacggagggt tcttgctcca tggatagttt attggcggtt ctgtcggaga aagatccgca
     4501 tcgagcgaca gccgtgatgt attactcgtg gattaccgag aaacctttct tgaatcactc
     4561 gttattatat agtactttat atcaaggtat aaacggtatt tctaggcatc ctgttttttc
     4621 tttatatgat atgggtgtgg aagaaggata tacgattggt ggatattata atagcgctaa
     4681 aacgattgag actgctctaa tccccttgct acaacaagtt tataacggtg aagatatggg
     4741 caagatcccg gtttcgacgg taaatgatcc tcataaatat ttgaattatg cttcgttgat
     4801 aagtgcgata tctaatgaag ataatttccc gcgtgatgcg atctacttga atgcgcctcc
     4861 ctctttcttg gaaaaatatt ggatgcaact gttaggcttt ctgatattct ttctggtagt
     4921 cgtgttttta gcgtggcatt acgtgtatcg ttctaagcaa aagatgaagg aagtagagtt
     4981 gaggttattg tcccgttacc gtgatttatt taataatatg ccgttacctt atatacggca
     5041 gcgactgatt cgagaaggta cgcaaatcga tgtgcaggtt ttagatgtga accatgcttt
     5101 cgaggagaaa atcgctccta aagattttgt ggtaaataag cgtggaaaag agatcgcaaa
     5161 tttgattggc gggagttatc ctttgcttct atcggcagtg cctacggttt tagagagtgg
     5221 aaaatccttc acttatgagt attattttga gccgacaggg ctttactata cgattatcat
     5281 catgcctacc tcggaagaga atgtggttga tgcgtttttt attgatatta cggatatcca
     5341 taaattccag acgcatttga aagccatgaa tcataagctg gctatggcgt tagaggcggc
     5401 agatctttta ccgtggcgat ataatctggc tgaagagaag attatctatg agtcgaaagt
     5461 acatccggga gataatatag agacagcaga ggtgcatacc catgaggttt cgttgaagga
     5521 atatttcagc aagatacacc cgtctttcag ggcttgcgtg gaaaaggctt tcgatgattt
     5581 gtgtaatggg aaaataaaga aagtacgaaa agaatattgt ctggagcggt tgattccggg
     5641 agaagatcgc catgagtggg aggagataca ggtaatggtc gaatatgatg cttccggtaa
     5701 accgaaagcg ttgatcgggt ctacgatatc tattaccgag cgtaagcaat tggaacatga
     5761 ccttcgaatg gctagggata aggcggagga gtcgaataaa ttgaaatctg cgtttttagc
     5821 taatatgagc catgagatac gtacaccgtt gaatgcgatc gtaggtttct ctaatatcct
     5881 cgcctcgacc gataaccttg aggataagaa ggaattcgct gatattatcg agaataataa
     5941 ttccctattg ttgcagttga taaacgatat cttggatttg tcaaaaattg aggcgggtac
     6001 cttggagttt acttatgact atgtggatat taacgctgta ttgagggatt tggagcaatc
     6061 ggctcatttg aagaataaga atccggatgt acagatctca tttaaggatt atctggagcc
     6121 ttgcgtgatt tatacggatc gaaatcgtct gtcccaactg atgatcaatc tgttgaacaa
     6181 tgccatgaaa tttacgcagg caggattgat ctcatttggc tataaactgc gggatgataa
     6241 tacgttgtgg ttctatgtag aggatacggg ctgcggaatc ccggagaata aacggaaaga
     6301 tattttcgga cgttttgtga aactgaacac tttcgctcaa ggaacaggat tgggtttaag
     6361 catctgtgag atgattgtta cccagatgaa aggaacgatc ggggttgatt ctatggaagg
     6421 gaaaggctct aagttctggt ttacattgcc ttttcagccg aagaaagaat tatttcctag
     6481 tgaagagcag aagcctgtta ctttggagaa gatcgcccga agtgaggtta cgatcttgat
     6541 cgctgaggac aattccagta attatcgcct gtttgagtct atattgaagc ctgaatataa
     6601 attgattcat gcatggaatg gaaaggaggc tgtggagcta ttttatcagc acaaacctca
     6661 gttgatcttg atggatataa agatgccggt catggatgga tacgaggcta ccgcagagat
     6721 tcgtaaggtt tctgctagcg tgcctattat cgcggtgacg gcttatgctt tcgcccaaga
     6781 tgagcaacgg atcattaata gtggatttga tgcctatacg gcgaaaccga ttaatgggaa
     6841 gatcttaaaa gacaagatat caactttatt gacgcatcgg attattctga tgtaatcgaa
     6901 gggctttgcg ggaagcagac cttataaaac aattaaagcc tgtctcacga caagccctaa
     6961 ccaaactttg ttaaccttaa atctaatact attatgaaaa aaccacgatg caaatatacg
     7021 gagttactat tatttgtcaa tagtttaagt gctaaattgt gttttgtaac atgtaataaa
     7081 atctaatagg aacttatgcc tcattgaaat ctttcgatag agtcgcatat attctttata
     7141 cctccctctt tttggatcat ctcgcctata tgagcggcat ttttcttata aagcggattg
     7201 gtgaccagat cacaaacctt gcgttcgatc tcctgctcgc tcgctttcgc tatcttaagc
     7261 ccttccggcc ctaaccctaa ttggtggatt cgataggacc aatagggttg atcgataatc
     7321 aacggagtga ttaattgggg ctttcccgcc cttcctacgc tatgggtcgt gccgcaacct
     7381 ccatgatgga taacgccgtc gcagtgcgga aatatcaaat tatgcggaac cggctgcttc
     7441 attaagaata aatgtttatc cgcttgtaag gtgattcctg tctttgccca accggaaccg
     7501 atgatgagcc gataatcatg tttcttgcaa atatcgacca aggctttgct aaaacggtta
     7561 ccatccttgg aactacaact cccgagggta aaaaagataa tagggctttg agcgctgtcg
     7621 acgaatgata tcatttcctc gtaagccttc tcatcatatt gaaaagtgtc attgaagcaa
     7681 tagcctccga tcgaccattt gaacgtccag tccggatcta tgtttcctag gtgctggctg
     7741 aaaagcaagt aattatatga acgctctccc gcatgataac caaaattacg aatcggtgcg
     7801 agtccgtatt tagcccggtt cttgttgatc gtgtctttga ccatgaaatt ggtcatccgg
     7861 ttcatcaact tccataagat ggcaggggtg atgatcgggt tgggtttggg aaatggcaat
     7921 acggccgggg gaatcttctt acccggcaag aacggggcgt aggcggtacg tatcaagggc
     7981 ttcttgcaat actcggcgat acttgcgaca gcaaattccg agttggtcga tactaaaata
     8041 tcatgctctt ttagtagggg aatcaattga tcgaactgtt tatcgatcac gttcctcatc
     8101 catttaagga atggccggaa tttatgtgag ttttgcgctg cgctatcgat catgccgccg
     8161 atatcgtcaa actgctgcaa tacgtattta aatccgtagg gtttaacggt ctcctcgaat
     8221 atttgaggga gattgatggt cacctcatgg ccacgtcttt ccaattcggc cgctatggcc
     8281 aaataaggaa ggacgtcgcc ttgtgagcct ctggttacta atagtatttt catgctacgt
     8341 ttatttatgg gctatgagga tcttgtttac cggatattca gttgacgcaa acgctcgatg
     8401 tccagatggt atttggcttc catcgtttgt agtttctgct cattgatggc taggggatga
     8461 ttcaatcgtt ttgtttcccg gtatccttta tatacggagc gaatcatctt acgtggattg
     8521 aaaatgatgg atgaggtgat ccaacagccg tgcgtacacc aacagttggc tttataccca
     8581 tgtccgatag cgactatttc ctgtttcatc gcttcgctat tcatcacttt acttatatcg
     8641 caaccatact cttttatatt tccgagcggt tcccgtagct cgcaggcacg aaaacgtccg
     8701 tcgtagtcga ttaccaaggt agtctctccg gccgtacaat ccatccccca aggggtcggg
     8761 tgatctatgt tgctggcacg cacattatat aaggtacgta taaggccgag atagaagaag
     8821 cgtgtgatcg gtttccttaa gccggtggta tccgctacca tccgatccgc ataagcagaa
     8881 tagatagggg atatgtcatc ttgtattttg cgtagcgttg actcggttag gattttcacg
     8941 ccatcgtcac gggtcatgcc tctggcagcc tcaatcgtat gcgtggaggt acggaaacgt
     9001 ccgtataccc aagtcatgaa gtcttctatc tggtctatat tgtatttcgt gataacggtt
     9061 gctatatttt ttaagacttt gccgtcatct ccgaaattct cctgtatctt acgcagggtt
     9121 tccaaggcct tatagaagtt tcccggtacg cctctctgtg tatcgtgggt cgtaccgaaa
     9181 ccatccaagg aaaggcttac gttaatatta caatccgggc agttctggcg gaaccgtttt
     9241 acccattcga cgatccggtc tggttttaag ccgttcgtag ggatgttcac atctttgata
     9301 tggttgtttt tgtagaataa ctccaatatt tccggtagat cctcacgcaa ggtaggctca
     9361 cccccggata tccataatcg attgaattgc ccggcggttt ctgatatctt cttgatttca
     9421 tcgaaagtga ggtcgggttg cttcttatcc atttcttggg catagaaaca cattgcgcat
     9481 ttggcgttgc atcggcctgt tacgaaaagg aagatcgact cgagttttct ttccgtgctc
     9541 attgccctga aagaactggt ggttcgtttt ttgtccattt tatttttgtt ttaccatttg
     9601 tcttatctgg cgcatgattt tttccttgtg tttgatcaac acccggagaa aataacataa
     9661 gaagccaaat aaaatactta ttagcatata ctatatgatc tttaaaggca aagatcgacg
     9721 ataaaatgac gctaaacaat ctctatttgc agtattttat ggtccatgtt taaaaggtag
     9781 gtctataaac aattaaagcc tgtctcacga caagccctaa ccaaactttg ttaaccttaa
     9841 atctaatact attatgaaaa aaccacgatg caaatatacg gacttttcaa ttcctgtcaa
     9901 ggattataat gctaaattat gttttacgac atataacaaa aacaaaaagg cgcctttctt
     9961 ttagagaaag acgccttttc catgatatac taatcaaata ttagtcttgt aatttagcgc
    10021 aaatgaactc gcggttcaaa cgagcgatgt tgctaacgga gatattcttc ggacattcca
    10081 tctcgcaagc acgtgtgttc gtacagttac cgaagccaag ctcatccatt ttagcgacca
    10141 tagctttggc acggcgagca gcctcgactt taccttgagg caacaaagcc agctggctaa
    10201 ccttagcgga tacgaataac atagcggaac cattcttaca agcggcagca caagcgccac
    10261 aaccgataca agcggcagcg tccatggcta agtctgcgtc cttctttggg ataggtatcg
    10321 cattagcgtc gggtacacca cctgtgttga cagatgtgaa accacccgct tggatgattt
    10381 tgtcgtaagc gtagcggtct accatcaagt cgcggataac agggaaacct gcggaacgcc
    10441 acggttcgat cgtgatcgtc tctccatcgt ggaaacgacg catatataac tggcaagtcg
    10501 tagctccagt tgccggtccg tgcgggtgtc cgtttacata caatgaacac atgccacaga
    10561 taccctcgcg gcagtcgtga tcgaatacga tcggttcctt accctcgttg accaactgct
    10621 cgttcaagat atccaacatt tccaagaaag agacactctg attgatcttc tcaattttgt
    10681 atgtctcgaa ctgtcctttc tccttcggac ctctctgacg ccaaacctta agtgttacac
    10741 ttatatcttt atccatgatt ctaatttttt ctgagattga tgattattac ttcttgtagt
    10801 tacgtgtttg aggaacaacg aactcatagt tcaaatcctc tttcaacatg acaggatctt
    10861 tgtcctcgcc ttggtactcc cagcaagata cgtacatgaa cttatcgtca tgacgcaagg
    10921 cctcaccttc ttctgtctgg tgctccgtac ggaagtgacc accacaagac tcagcgcggt
    10981 ccaaagcatc gtgtgccatc aatgtaccga tctcgataaa gtcagctaca cgtaatgctt
    11041 tctctaactc ggtattcaag ttgtctgcgt tgcctgggat gaatacgttg ctccagaact
    11101 ctttcttcaa gtctttcagc atctggatag cttcttgcaa accttttgcg tcgcgtgcca
    11161 taccgatatg ttcccacatg atatgaccta gtttgcggtg gatagtgtct acggtttctt
    11221 tacccttgac gttcatcaat ttttggatac gatccttgat ggccttttct gcctcgacga
    11281 actccggcag atccgtgctg aagcgaggaa cttggatttg gtcggacaaa tagttctgga
    11341 tcgtgtatgg taatacgaaa taaccatcgg ccaatccctg catcaaagcg gaagcaccta
    11401 aacggttcgc tccgtgatcg gagaagtttg cctcaccgat agcgaacaga cccggaatgg
    11461 aggtcatcaa ctcatagtca acccacaatc cacccattga gtagtgcaat gccgggtaga
    11521 tcatcatcgg agtctcgtat ggattatcgt tcgtgatctc ttcgtacata tcgaacaagt
    11581 taccgtattt ctgcttaacg acctctttac ccaagcgatt gatcgcgtcg gagaaatcca
    11641 agaatacggc caagcccgtg ctgttcacgc cgaaacctgc gtcgcaacgc tctttagcgg
    11701 cacgagaagc cacgtcgcga ggaaccaagt ttccgaatgc cggataacga cgctccaaat
    11761 aataatcacg gtctgcctcg ggaatatctt tacctttctt cgttccggcc tgtagagctt
    11821 tagcgtcttc cagtttcttc ggaacccaga tacggccgtc gttacgcaag gattcggaca
    11881 tcaaagtcaa tttagattgg aagtcacctt tcaccggtac gcaagtcggg tggatctgaa
    11941 ccatacaagg attagcgaag taagcgcctt tcttgtagca ttgccatgcg gcggaaccgt
    12001 tagatgccat agcgttggtt gacaagaaga acgtattaac gtaaccaccc gtagctacaa
    12061 ctacagcgtg agcggcgtaa cgctcgatct tacctgtaat caagttgcgg gcgatgatac
    12121 cacgagcacg accgtctacc ttaactacat ccaacatctc atgacgagtg tacatcttaa
    12181 ccttacccaa accgatctga cggctcaacg ctgaataagc gcctaacaaa agctgctgac
    12241 ccgtctggcc acgggcgtag aacgtacgcg atacctgagc gccaccgaat gaacggttat
    12301 ccaacaaacc accatattcg cgagcgaaag gaacgccttg agccacgcac tggtcgatga
    12361 ttgagttaga aacctcagcc aaacgataaa cgttagcctc acgagcacgg tagtcaccac
    12421 ctttgatcgt atcgtagaac aaacggtaaa cagagtcacc atcattctgg tagttcttag
    12481 cggcgttgat accaccttga gcggcgatag agtgcgcacg gcggggagaa tcttggatac
    12541 agaagttcaa tacgttgaat cccatctctg ccaaagatgc ggcagcggaa gctccggcca
    12601 aacctgtacc gactacgata acatccaaac gacgcttgtt agcggggttc accaatttct
    12661 ggtgattttt ataattagtc cacttctcag ccaacgggcc ttgaggtatt ttagaattta
    12721 tttcagacat aatgatttaa tttcaaaagt tcttaattat aaaacctgta gcttgcaatt
    12781 aagcacctac tccgtttagg aagaagatga tagtaatgat cgcgaaaagt ccgcaaataa
    12841 ccgtagctac gatcttagag atacattccc aacggttcat ccagatcgta ttattccaac
    12901 caattgtttg gatagcgctc cagaacccgt gagtcaagtg gaaccacaaa gccacgtacc
    12961 agatcaaata aagaacagtg atcacggcat taccttggaa gtaatagttg ataaaagcgg
    13021 ctccgtcttg tggagatacc atagctgacc ccaatgcaac ttcgtgatga ccgatcaatt
    13081 cggcgaacat catcttatac cagaactggc tgaagtgcaa cagcatgaac aggataacaa
    13141 tcaaacccaa aacgaacatg ttctgagatg cccattccac gcctttcgga cgagcgttga
    13201 tagcgtaacg gtcgttacca cgtgccttac ggttttgcaa ggtaagaatg atagcgtaca
    13261 cgaagtggat cacaacgcct gcggccaata cgagagtagc tgccacagcg taccaattag
    13321 agcccaacag cgaacaaacc atgttataag cctctccgga gaaaacggcc gccacgttca
    13381 tcgacaggtg gaacaataag aacagaacaa gaaagaggcc tgatatactc attatcagct
    13441 tcttcccgat agaagaatta agtaaccaca taagataata atttaagtta tttaattgta
    13501 tttagaaatt tctacttaaa ctatgtaatt atcacgcaaa ggtatgctaa atccatatat
    13561 tgcgcaaacg attaaagaaa tatttctgca ttaatgggag aggtcagggc atgtgtcccg
    13621 acacatggaa taatgcggaa ggaaaaggct ttccttatga ataatttata tacatttgcc
    13681 tatatgcgta aggatttgaa tgggtcacgg catttttcca tagggatcaa gtttacgatc
    13741 ttattattta cgatcgtgat cttggttctt gtgctttttt catataggag cgacaagcat
    13801 ggcaacctgt tctggcaggt agagaaattg attccgcatc atccggacag tgctttggtg
    13861 ttattagata aagtgaggga tatcaatgga ttatcgcttc gagagaaagc ccgttattgt
    13921 ctgttatgga ccgaatcacg ggatgaggcg ggattgaggc atacatcgga ttccataatc
    13981 tctatcgcta cggattatta taggacgaca cgaggctgtt actggcctcc caaagcttgg
    14041 ttttaccggg ggaaagtcta tgaggatatg gatcaaccgt ccctagcttt ggaatgctat
    14101 ttacgtgcgt tggaatatga gggagagaat tgggattatg aattctgggg aaggttatat
    14161 aaccaaatgg ggatgctgta cgccgagcag gaattatatg gcaaggctat gtcttttttg
    14221 agaaaagcga gtgctcaata tcagttattg aacgatgcgg ccggacaaga ccggatactg
    14281 accgaggtca agaaatacga gatgttacgg gattctatcg gatcactatc agcgagagaa
    14341 tcgatttatc agatcacttc ccgctatgat gtaaggccga tccgtgagga cttgtctaag
    14401 aaagagttga tgctattaca aaggggacag gagcgttatc tgtacgcatt tattatcggc
    14461 ataatcctat ttatttgctt cctcctttat cggcgatgga gaaatacgca ggaaaacgct
    14521 cttcgaaggg aagaagcctt gcgacgttcg attgctagcc agcaacaacg tatgcgagaa
    14581 gaaaaagaag agaatgaacg gcaaatcacc cttttggaaa aaagaattac gaaaataaag
    14641 gaagaaaagg atcaagagtt gatgttggtt tccttacaat tggaaaaaca acggctggaa
    14701 atttgtaacg agtcgattct taataaggag agtaagcatt tattatctgt cgcgatcttg
    14761 cggaaatcgg aggtctatga gaagtttcac gatcgggatg ccggcaagat tatctctgag
    14821 gattgggagc ttttggaggt tttgttgaat aaggcttatg atgactttac cttacggctg
    14881 aaaaagctat atcctgttat ttccgatacg gagttgaagg cctgtatgct cacgaaaatc
    14941 ggtgttcccg ccaaccagat cacacgggta ttgaaatata atagttcggt acttcgtcct
    15001 cgtctattcc ggaagatttt taagaaagaa ggttctacgg aggcatttgt ggagtttata
    15061 tcaaactttt gattattata tatttatagc ggtcttggca ggtttgttct catttttgtt
    15121 ctcatttatt atgtgatttg tgagatatac gggatatttt tggaggcaaa aaagcatggt
    15181 tatgaaaagt gtaaagttag cctctatctt gttttactaa agtttcccac ccaaataaat
    15241 agatagaaaa ataacagttt gtcgaat
//
