LOCUS       c00068_gnlPro..        22127 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KFOPJACC_68.
ACCESSION   c00068_gnlPro..
VERSION     c00068_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:03:40
            Original ID  :: gnl|Prokka|KFOPJACC_68
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22127
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22127
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7570:12127]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7571..12127
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..22127
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22127
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(217..759)
                     /locus_tag="ctg68_1"
                     /transl_table=11
                     /translation="MIEEILAYNKQFVENKGYESYIDNKYPDKKIAILSCMDTRLTALL
                     PAALGIKNGDVKMIKNAGGVISHPFGSVIRSLLVAIFELGVEEIMVIAHSDCGACHMHS
                     EVMLEKMKARGINPDYIDMMRFCGVDFHSWLDGFEDTEKSVRGTVDFIVRHPLIPSDVT
                     VYGFIIDSTTGELTRIV"
     CDS             complement(869..2893)
                     /locus_tag="ctg68_2"
                     /transl_table=11
                     /translation="MKSTIYKIAALTFAVASMSACSLDEYNPSQKTGDEILATFDGLKG
                     LQSYCYSSLYGQLFSVYDFLSVAEGGTDCWITPAGNPDYAKQVIYYDGLATNTNATNKL
                     FGQAYSMIGNCNAVVNRAELLTDGNEKDITTLVAEARCLRAFYYSILVNTYGNVTLTLE
                     ESSQDPILTPQRNSIEELYTQIIDDLKFAANNLEDTPYDNNRARVTKKTALGLLARVYA
                     QGGGEYGLTEEGVSYWQRAKEVAEDMILAYGDCLYDDVEDVWAPANNRNNKEALFIAAG
                     PDATNLENWNAGTQCNNNFTYMYPKPNTLTIYPTPDNQNYWYGRTNNNTLAPSKYLLDC
                     FDADYDKRWEVTFTTAFVQFSAVQSGGSYLFTNKKQTLDDGTKPKIGTKHGVNDNISSF
                     TILTQNIIDTYGLDAKFHNEYIYPYGDLNYTYYDGTWAPKMIAKVWPKGENSGDPSKLQ
                     EVKNPYVIPYPVAEDDDRICFYLSKERLSDAEKAKRRYYVINIDDLFDNGQYRKTDIKV
                     TNDKNMYPGFNKYNWLSEDSYSSNLQRKTGDVFIMRMAEVYLIAAEANQQLGNGGKAAE
                     YLNVLKKRAARNDASYNAMKLSNATQNDVMDEYARELCGEYQRWVLMKRHKDSFKQRLA
                     VGNPRAAENFDENKHYLRPISFNFLSQIDNAEEYGNNGY"
     CDS             complement(2918..6028)
                     /locus_tag="ctg68_3"
                     /transl_table=11
                     /translation="MVQVVTQTKTVKGTIIDESGEPLIGVSIVVKGTSTGTITDFNGNF
                     SIDLPAGRKELVISYIGYKEQTVTVTGNGPVNVKMVSDTQALDEVVVVGYGTMKKRDLT
                     GAITSVKSEDVVMNPSSNPMQALQGKVAGLDITRESGQAGSGVKMQLRGNRSFQKDSGN
                     PLFIIDGMPGDYSTLNPNDIESIEVLKDASSTAIYGSSGANGVILITTKGGKEGKAIVN
                     FNAYVGVNGWSRTPEMRSGESYIQTLRDASVGAGDGRWSSVADDKNLFTTDAEWSAHQN
                     GQYIDWVDALLKTSVTQNYSVSVAGGTEKTKAYFSLNFSNEDGQFAQDSYKLYSSKIRV
                     DHKIKKWMKVGIDAQLSYVHQNKADSDLQTLMASNPLGSLYNEDGSINPQPVADPSSTV
                     YNYLLNEDKSLYRNQAQNLKVYFNPYLEITPLKGLTFITRAGASLGYSRSNTFTGEGSV
                     QWYKANQTADGIKAQVKDNRSYNYKWENILTYNFQIKKVHDITLTAVTSWNHNRSDVTT
                     LYQKGVSDNKFLWHNILDGNSATSGSTSYSMSKGMGYVGRLNYSYMGRYLFAASVRHDG
                     SSRLAEGNKWDTFPAFSLGWRISDEKFMESTTNWLSNLKIRFGYGVTGSTAGIDPYSSA
                     ASLDATAVNMILGGVLTPIYKFSQNIPNYLLTWEKSYNTNIGIDAAFLNNRIDVSMEYY
                     NTKTKDVIWNKALPVINGAFSPDGGPKANYTTNLNMCETSNKGFELALNTRNIITKNFI
                     WSSSVTFNHNKEKITKLSGGDSDVLNNGDTGYALALGEAINSYYHYKLDGVWQKGEETD
                     AAVFGAAPGDLKINIPNLVKESDGRFYKIDEETGSAAVDENGNVIYYTSDNKYTPNDAD
                     YQILGHNSPDWSLGFQNNFTWKDFDLSVFVYARYGQMFAYDMLTSYDPKGIRNFPTYFN
                     YWTENNPSNDFPAANANKGLEQYTGYYALRYVDGSFIKIKNITLGYSLPKSILKSAGIE
                     KCRFYATITNPFVFAKSHLLKDYDPEMNGSLKYPLTKQFVFGVNVTF"
     CDS             6397..7395
                     /locus_tag="ctg68_4"
                     /transl_table=11
                     /translation="MPLKLTTYYHGKDIPELPGKNAFHSKELFQIYEATPGYTPLLIVA
                     TEDGRPMARLLAAIRKAKKWLPSSLVKHCVVYSEGEFLDESLSTNKEKAEEVFGDMLEH
                     LTQEASRSCVLIEFRNLNNSMFGYRVFRANDYFPVNWLRVRNSLHSMKKTEDRFSPSRI
                     RQIKKGLKNGAKVEEAHTVEEIHDFSRMLHKVYSSRIRRYFPANDFFRHMNNMLIKGQQ
                     AKIFVVKYKEKIIGGSVCIYSGDDAYLWFSGGMRKTYALQYPGVLAVWKALEDAHQRGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRINWSWLNKLLVKFYV"
     CDS             7571..7975
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_5"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.2e-23, bitscore:
                     75.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAEGKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             8004..9557
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_6"
                     /sec_met_domain="CT_Btheta (E-value: 7.6e-290, bitscore:
                     952.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             9589..10509
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_7"
                     /sec_met_domain="OAD_gamma (E-value: 2.6e-15, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILIDNQSNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGKKLLDQIVVPAGALGPNQSYARVSDGAAEW
                     EVKSGSGDKYVTPSTNNKTLDSNSKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             10534..10965
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_8"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.5e-21, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPV
                     AKPVTVRPMPNAPAAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             10967..12127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_9"
                     /sec_met_domain="OAD_beta (E-value: 2.7e-153, bitscore:
                     501.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLVFIYLAIAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFVIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             12422..13762
                     /locus_tag="ctg68_10"
                     /transl_table=11
                     /translation="MKRIIILFFLCCTIPLIAQHTDPIQEAMANYDYETALSLIAQKKT
                     TPPLLLQKGKALRGLGLTTEALATYQEIICNDTTNTRAFIEAAECCRALAKYNQALKYY
                     EHALDLNPENKYVRIQYISLLLSQQKFSEALGESSLMTEKDSSAIVLHLQAQSFEGMGE
                     LLPAAGCYYNIQAKYPDDYLAASKLGALNISGSYFDEAIEATEKYRQIDSTNISVNRQN
                     ALAYCLKQDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAAEKYYEAHDFLEVARKYDP
                     NNINLLYYLGRACSKTSWKKEGVDYLEKAIDLSIPKDSSMTRLYIGMTDCYKMAQMYKE
                     QIASIKERYQRYDKQNHKLLYDMAYIYFYDLKDKKNAERYLEAFLKTRPKDTKEEAEMN
                     ERGELVLGKSNYYNAAANWLKDIQSKQKIEDFFQNSSPQLPLPKKDK"
     CDS             complement(13847..14851)
                     /locus_tag="ctg68_11"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAVRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAQ"
     CDS             15149..15322
                     /locus_tag="ctg68_12"
                     /transl_table=11
                     /translation="MMMTYLFYKTDYLYRSFFHKTFFYFTEKHYLCALKMTITLFLTKI
                     VTEYKLKKQILK"
     CDS             15319..15573
                     /locus_tag="ctg68_13"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             complement(15654..16868)
                     /locus_tag="ctg68_14"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIDLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVTGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRIPRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDSLWQDNVEGVRHRHIADF
                     LLDDA"
     CDS             17000..17470
                     /locus_tag="ctg68_15"
                     /transl_table=11
                     /translation="MTKSDLLPNKESTFTRLINKKMEITDLKQMTKEEVFNFIRQRLSF
                     SKELQEQFRHVNKDDLAKEHRRFEMSGNESKTGQCTIFNTAILNEFADLGIYDYTSYLF
                     LDFHNGTPTVYLKYFSENENLEYTFTGYTTTEIIFAILELTIFSGKPKRNRS"
     CDS             18204..18635
                     /locus_tag="ctg68_16"
                     /transl_table=11
                     /translation="MPKWISVEKAVIKYHIEKEAILLWVEMGQFPMLYIDNVPNVDEEC
                     ILELFRRSKAGITAEYIDTLEQLCIDKTMVCEKYAHIIQLKEKEIQLQKEINTLINEIQ
                     AAMKRQNERIRDLKKAIGENNNVIRSDSWIKRLRKRFQW"
     CDS             complement(18898..19314)
                     /locus_tag="ctg68_17"
                     /transl_table=11
                     /translation="MKLIFFHRRAEYNPCHSTRKPFSTMHVIVWEKPVGGVFVVGAAEI
                     VFIFCQCPCNGKAGSVCSLQAEIGVVPSHPVYQFFYLVCTAHRFSQCQQCAVILFRILA
                     DNSCPTGNRQATVILHRFFHTDFFVLKCSHFSSC"
     CDS             19647..20951
                     /locus_tag="ctg68_18"
                     /transl_table=11
                     /translation="MTTSNSANTKQSNNASQKRKPIHNGYFNHPTSSSSNIPMSILIRE
                     QGLEIYGLYWVMLEEAHAQLKCCVNIQTMGIIANIFHAQPEHLELLYHHYFRRPGKGYN
                     SHILYADFCEESAIRSYFPHPLLAYTDNELLRMIMQDGLKAYGLYWLVMEKLYQQPQHF
                     LAPQTASFIQNLYDVSDELMESVLYNYGLFYLDEKMNLHSKAIDDYREALDNMEDEKKR
                     NTKPHVNNSLKANGNAEDFNTREMKKTSNIQKNPSPIINKEINKKNSSSEESGKEKEEE
                     NGLKVTDLNAVTPDMRPNAWEENLQEAMNDTSWYEVVAIQSGIPRLMMEEKEWFFNYLR
                     EQIILRGNESSMNSLHEIKNYFANLTRQGSHVSSTTQVALKKFLKNRQEQQQCSPYETI
                     TNGIRTYDGHPIPAYAKPRPSAAHIWNPVTNEWTR"
ORIGIN
        1 aacgagtgca ccagtcaaag aaagtatata accgcagaaa gataaaggca gccgataaaa
       61 agctgcctta tttttttgtc ttcaaaatag cgtcactatc ctccagacat agcgacacta
      121 tacaatagga atggcgtcac tatcatgata ggatagcgtc actatattta ggggattaaa
      181 aagaagttta tctatttacc taatctatct aattatctat acaatccgag ttaattcccc
      241 ggtcgtagaa tcaataataa acccgtagac tgtcacatct gaagggatca aaggatgacg
      301 cacgataaaa tccaccgttc ctctcaccga cttttccgta tcttcgaagc catccagcca
      361 cgaatgaaag tcaactccgc agaaacgcat catgtcaata taatccggat tgatcccgcg
      421 tgctttcatt ttttcgagca ttacttcact gtgcatgtgg caagctccac agtcagaatg
      481 agcaatcacc attatttcct ctacccccaa ttcaaaaata gctacaagta aactacgtat
      541 cacgctaccg aaaggatggg aaataacgcc acctgcattt tttatcattt ttacatcgcc
      601 attcttaatt cctaatgcgg ctggaagcaa agctgtcagt cgggtgtcca tacaggaaag
      661 aatagctatt ttcttatcgg gatatttatt gtcaatatac gattcgtatc ccttgttctc
      721 aacaaattgc ttgttgtaag ctaaaatttc ttctatcata gttccgctta aattataaag
      781 ctctgtttga tgatacaaag atatagaaaa aagggacata tcatcacgac atatcccctc
      841 tttaatctaa atttaatctg taagagtact aatacccatt gtttccatat tcttctgcat
      901 tatcaatctg actcaagaag ttaaaagaaa tcggacgcaa ataatgcttg ttttcatcaa
      961 aattttcagc tgcacgagga ttaccaacag caagacgttg tttaaaagaa tctttgtgac
     1021 gcttcatcaa tacccaacgt tgatattctc cacataattc acgagcatat tcgtccataa
     1081 catcattctg tgtagcatta ctcaatttca tagcattgta agatgcatca ttgcgagcgg
     1141 cacgcttttt cagtacattt aaatattcag cagcttttcc gccatttcct aattgttggt
     1201 tagcttcagc tgcaatcaga tatacttcag ccatacgcat aatgaacaca tcacctgtct
     1261 tacgttgcaa attgctacta tatgaatctt ccgacaacca attgtatttg ttgaaaccag
     1321 ggtacatatt tttgtcatta gtaactttta tatctgtttt acgatattgt ccgttatcaa
     1381 acaaatcatc aatattgatt acataatatc tacgtttcgc tttctccgca tccgaaagtc
     1441 tttcctttga taagtagaaa cagattctat catcatcttc agctacaggg taaggtatca
     1501 cataggggtt cttcacttcc tgcaatttgg aaggatcacc gctattttca cctttcggcc
     1561 aaaccttggc tatcattttg ggcgcccaag ttccatcata atatgtataa ttcaaatcac
     1621 cataaggata aatatactca ttatggaatt ttgcatccaa tccataagta tcgattatat
     1681 tttgagtaag aattgtaaat gaactaatat tatcatttac gccatgtttt gttccaattt
     1741 ttggttttgt accatcatcc aatgtctgct tcttattagt aaataaataa ctacctcctg
     1801 actgtacggc agaaaactgt acaaaagccg tagtaaaggt tacttcccac cgcttatcat
     1861 aatcagcatc aaaacaatcc agcaaatatt tggaaggtgc caacgtatta ttattagtac
     1921 gtccatacca ataattttga ttatccggag taggataaat agtgagagta tttggctttg
     1981 gatacatata agtaaagttg ttattacatt gtgttccagc attccagttc tccaaattcg
     2041 tagcatccgg accggcagca ataaataaag cttctttatt atttcgatta tttgccggag
     2101 cccaaacatc ttccacatca tcatacagac agtcaccata cgctaaaatc atgtcctctg
     2161 ccacttcttt agcacgttgc caataagata ctccctcttc tgtcagccca tattcgccac
     2221 caccttgagc ataaacgcga gccaaaagtc ctaacgcggt tttcttagtc acacgcgcac
     2281 gattattatc ataaggagta tcttcaagat tattggccgc aaatttcaaa tcatcaatta
     2341 tctgcgtata tagttcttca atagagttac gctgcggagt caaaatagga tcttgagacg
     2401 attcttccaa tgttaacgtt acattcccat acgtattcac caatatggaa taataaaacg
     2461 cacgaagaca gcgggcttca gccactaacg tcgttatatc tttttcattg ccatccgtta
     2521 gtaattcagc cctgtttact actgcattac aattaccgat catagaataa gcctgaccga
     2581 ataatttatt tgtagcattc gtattcgtag ctaaaccatc ataataaatc acctgcttgg
     2641 cataatccgg attaccggca ggagttatcc agcagtccgt accaccttca gccacagaca
     2701 agaaatcata gacactgaat aactgcccgt aaagtgatga ataacaataa gactgtaatc
     2761 ctttaagccc atcgaacgtt gcaagaattt catctcctgt tttttggctt ggattatact
     2821 catcaagcga gcaggcagac attgaagcca cagcgaatgt aagcgctgct attttataga
     2881 ttgtactttt catttcaata ctttttttag tgaaaaacta gaatgtaaca tttacaccaa
     2941 atacaaattg tttggtcaat gggtacttca gagaaccatt catttcggga tcatagtctt
     3001 tcagcaaatg gcttttcgca aatacaaacg gatttgtaat ggtagcatag aaacgacact
     3061 tctctatacc ggctgatttt aagatagatt tcggcagact atatcccaat gtaatgttct
     3121 taatctttat aaacgaaccg tctacatagc gtaatgcgta atatcccgta tattgttcga
     3181 gacctttatt agcattggcg gcaggaaaat catttgaagg gttgttttca gtccaataat
     3241 taaaataggt cgggaagtta cgtataccct tcgggtcata agacgtcaac atatcataag
     3301 caaacatctg tccgtaacgt gcataaacaa acacacttaa atcaaaatcc ttccaggtaa
     3361 aattattctg gaatcctaaa gaccaatccg gagagttgtg acccagaatt tgataatctg
     3421 catcatttgg agtatattta ttatcagaag tgtaataaat aacattacca ttttcatcta
     3481 cagcagcact acccgtttct tcatctattt tatagaatct accatcagat tcttttacta
     3541 aattaggtat attgattttc aaatcaccag gtgcagcacc aaataccgcc gcatcagttt
     3601 cctcaccttt ttgccataca ccatccaact tataatgata ataagagtta atagcttctc
     3661 ccaatgccaa tgcataaccg gtgtcaccat tattaagcac atctgaatct ccaccggaca
     3721 atttggttat tttctcttta ttatgattga aagttacact tgaactccag ataaagttct
     3781 ttgttataat attacgtgta ttaagagcca actcaaaacc tttattgcta gtctcacaca
     3841 tatttaaatt agtagtataa ttcgctttag gtccgccatc cggggagaat gctccattaa
     3901 taacaggaag tgccttgttc catataacat cttttgtttt tgtattataa tattccatac
     3961 tgacatcaat gcgattattt aagaatgcag cgtcaatacc aatattcgtg ttatacgact
     4021 tttcccatgt aagcaaatag ttcggaatat tctgtgagaa tttataaatc ggcgtcagaa
     4081 cacctcctaa tatcatattt acagcagtag catccaatga tgcagcagac gaatacggat
     4141 caatacccgc tgtactaccc gtaacaccat atccgaagcg aattttcaga ttactcaacc
     4201 agttagtcgt actctccata aatttttcat cagagattct ccatcccaaa gaaaaagccg
     4261 ggaaagtatc ccatttatta ccttctgcca gtctggaaga gccgtcatgg cggacagatg
     4321 cagcaaataa atacctaccc atatatgaat agttcaaacg gccgacatat cccatcccct
     4381 tagacatact ataagaagta cttcccgaag ttgcggaatt accatcaaga atattatgcc
     4441 ataagaattt attatcagaa acaccttttt gatacaaagt agtgacatcg ctacgattgt
     4501 gattccaaga tgtaactgca gtaagagtta tatcatgcac tttcttaatc tggaaattgt
     4561 aagtaagtat attttcccac ttataattat acgaacggtt gtccttaact tgcgccttaa
     4621 tgccgtctgc cgtttgattt gccttatacc attgaacaga cccctctcct gtgaaagtgt
     4681 tactacgtga atatcccaaa ctagcaccag cacgagtaat aaaagtcagc cctttaagag
     4741 gagtgatttc caagtaagga ttaaaataga ccttaaggtt ttgagcctga ttgcggtaca
     4801 aacttttatc ctcatttaaa agataattat atactgtaga tgaaggatcg gcaacaggtt
     4861 gcggattgat gcttccatct tcattataca acgatccaag aggatttgac gccatcaaag
     4921 tctgtaaatc agaatcagct ttattttgat gtacataaga cagttgagca tcaatgccca
     4981 ccttcatcca ctttttaatc ttatgatcta cccggatttt agatgaataa agtttatagc
     5041 tatcttgtgc aaactgccca tcctcattag agaagttcag agaaaaatat gcctttgtct
     5101 tttccgttcc accagccaca gaaacagaat aattctgtgt tacactggtt ttcaacaaag
     5161 catccaccca atctatatat tggccatttt gatgtgcact ccattcagca tcagtagtaa
     5221 acagattttt atcatcagca accgaactcc aacgtccatc gccagcacca acagatgcat
     5281 ctctcaaggt ttgtatataa ctttctccac tacgcatctc cggagtcctt gaccagccgt
     5341 ttacacctac gtatgcatta aaattaacaa ttgctttgcc ttccttacca cctttagtag
     5401 taattaaaat aacaccgttc gcaccacttg aaccataaat agctgtcgaa gaagcatctt
     5461 ttaaaacttc aatgctttca atatcattcg gattcaatgt agaataatcc cccggcatac
     5521 catcaattat aaataaagga tttccggaat ccttctggaa tgaccggtta ccacgcaact
     5581 gcatctttac tcccgaaccg gcctgtcccg attcacgcgt aatatccaat cctgccacct
     5641 taccttgtaa agcctgcatc ggatttgaac ttggattcat cactacatct tcacttttta
     5701 cagaagtgat agctcctgtc aaatcgcgtt ttttcatcgt accgtaaccc acaacaacca
     5761 cttcatccaa tgcctgtgtg tccgaaacca ttttcacatt gaccggtccg ttgcctgtca
     5821 ctgtcaccgt ttgttctttg taaccgatat aagaaatgac cagttctttt cttcccgccg
     5881 gaagatcgat agagaagtta ccgttaaaat cggtaatcgt acctgtactt gttcctttca
     5941 caacgataga aactccaatc agcggctccc cgctttcatc aatgatagtt cctttcacag
     6001 ttttcgtttg tgtgacaact tgcaccatag tattagaaac tccatcttct gcatacacag
     6061 aatatgacag aggggcagac aataaagaca gccctaaaat catggaagcg cgtctatgat
     6121 gattcttcca tgcttcaaca aatgcattac atctcattcg ttctaattta aagttaatat
     6181 taattctcgt tgttttgcaa aaactattcg attataatct taattaaaga cgaatctaat
     6241 tttaatacgt actcactttt cataccatat ttctcctata aaatatattt tctccattaa
     6301 atacgcaact atatattata ctttacttca agcagctcca acaaattctt tgttttgttg
     6361 ttgaataaag aataaaaagt gtaaatttgt acctagatgc cacttaaact aaccacatat
     6421 tatcatggga aggacattcc tgaattacca ggaaaaaacg ccttccattc caaagagtta
     6481 tttcagattt atgaagcgac tccgggctat actcctttat taatagtggc aacagaagac
     6541 ggcagaccta tggcacgcct gcttgccgcc atccgcaaag cgaaaaagtg gcttccctcc
     6601 tctttagtga aacattgcgt agtatatagc gaaggtgaat ttctggatga gtcgctttcg
     6661 accaacaaag aaaaggcaga agaagtcttt ggcgatatgc tcgaacatct cacacaagaa
     6721 gcatcgcgta gctgtgtcct gatcgaattc cggaacctca ataattcgat gttcggttac
     6781 cgggttttcc gtgccaatga ttatttccct gtcaactggc tgcgggtacg caattcgctg
     6841 cacagtatga aaaagacgga agaccggttc agcccgtcgc gcatccgtca gataaaaaaa
     6901 ggactcaaga atggagccaa agtagaggag gcacataccg tggaagaaat acacgatttc
     6961 tcacggatgc tgcacaaggt ttattcctcc cgcatacgca gatatttccc tgccaacgac
     7021 tttttccgcc acatgaacaa tatgttaatc aaaggacaac aggcaaaaat attcgttgtg
     7081 aaatacaaag agaaaatcat tggcggttct gtctgtatct attcgggaga cgacgcatac
     7141 ctttggtttt ccggaggaat gagaaagaca tacgcacttc aatatccggg tgtgctagcc
     7201 gtttggaaag cattggaaga cgcacaccaa cggggattcc gccacatgga atttatggat
     7261 gtaggacttc cgttccgtaa acacggttat cgtgatttcg ttcttcgctt cggaggaaaa
     7321 caaagcagta cccgccgttg gttccgcatc aattggagtt ggctgaacaa actcttagtc
     7381 aagttttatg tctaaatgta atctcaagat tacaaaacaa tgttttatgc tcctttccca
     7441 ccattttttc tgtttaataa tccaataatt aaatgcagaa atatttcttt attagataag
     7501 aaatgtcttt ctttgtgctg ttttatgcct tataagcaca gatttaaaac caaataaaaa
     7561 aagtatagtt atgaagattt cacacattga acatctgggc attgctgtaa aaagcatcga
     7621 agaagccctt ccttactacg aaaatgtatt aggtctgaag tgttacaaca ttgaaacagt
     7681 ggaagatcag aaagtaagaa ctgctttttt aaaagtgggc gaaacaaaaa ttgaactgtt
     7741 ggagcctact tgcccggaga gtactattgc caaattcatt gaaaacaaag gtgcaggcgt
     7801 tcaccacgtc gcatttgctg tagaagatgg cgtagccaat gcgctggcag aggcagaagg
     7861 caaagaaatc cgccttatcg acaaagctcc ccgcaaaggt gctgaaggtt tgaatatcgc
     7921 tttccttcac ccgaaatcaa ctttgggtgt gttaacagaa ctctgcgaac attaatcata
     7981 aactctaaaa ccaacaagaa ctcatgagta atcaacttga aaaaattaaa gagcttattg
     8041 aacgccgtgc cgtagcacgt atcggaggcg gtgaaaaagc aattgcgaag caacacgaaa
     8101 aagggaaata cacagcacgc gagcgtctgg ctatgctgct tgacgagggt agcttcgaag
     8161 aaatggacat gttcgttgag cacagatgca cgaacttcgg catggagaaa aaacattacc
     8221 cgggagacgg tgtagtaacc ggctgcggta cgatcgaagg acgtctggta tatgtgttcg
     8281 cacaagactt cactgtttct gccggttcac tgtcagaaac gatgtcattg aaaatttgta
     8341 aaatcatgga tcaagccatg aagatgggcg ctccctgtat cggtatcaac gactcgggtg
     8401 gtgcacgtat tcaggaaggt atcaacgctt tggcaggtta tgcagaaatc ttccaacgca
     8461 atatccttgc ttccggtgtt atcccacaga tttcaggtat cttcggtcct tgtgccggcg
     8521 gtgctgttta ttctccggct ctgaccgact tcacgctaat gatggaaggt acttcttata
     8581 tgttccttac cggaccaaaa gttgtgaaga ccgtaacagg tgaagacgtt agccaggaaa
     8641 acctcggtgg cgcaagcgtt cactccacta aatcaggtgt gactcatttc accgctaaaa
     8701 cagaagaaga aggtttcgag ctgattcgta aactgttgag ttatattcct caaaacaacc
     8761 tcgaagaagc tccttatgta gattgcacag acccaatcga ccgtctggaa gattctttga
     8821 acgatattat ccccgacagc cctactaaac cgtatgacat gtacgaagtg atcggcgcta
     8881 ttgtggacaa cggtgaattc cttgaaatcc agaaagatta tgcaaagaat atcatcatcg
     8941 gtttcgcccg tttcaacgga caatcggtag gtatcgttgc taatcagcct aagtatctgg
     9001 ctggtgtgct cgatagcaac gcatctcgta agggtgcacg tttcgttcgt ttctgcgatg
     9061 cattcaatat tcctatcgta tcgttggtag acgtaccggg attccttccg ggaacaggtc
     9121 aggaatacaa tggcgttatc cttcatggtg ctaaactgtt gtatgcttac ggtgaagcta
     9181 ctgtgcctaa ggttacgatt acattgcgta aatcctacgg tggttctcac atcgtaatga
     9241 gctgtaagca acttcgcggt gacatgaact acgcatggcc gactgctgaa atcgcagtaa
     9301 tgggtggagc aggagcagta gaagtattgt acgcacgcga agccaaagat caggaaaacc
     9361 ctgctcaatt ccttgcagag aaagaagcag aatacacgaa attgttcgcc aatccttaca
     9421 atgcagctaa atatggctac atcgacgatg tgattgaacc gcgcaacaca cgtttccgtg
     9481 tgatccgtgc tttgcagcag ttgcagacta agaaattgag caatccggct aagaagcatg
     9541 gtaatattcc gttgtaatcc tacttttcac attaaaacaa gaacgattat gaacaaaacc
     9601 aaaatcggaa tattcctttc tttgctgttg ctgattggtc tgacttcttg tggagagcaa
     9661 aagtcgaaca ataagctggt gctaaacgaa atcctgatag acaatcagag taattttcag
     9721 gacgattacg gattgcacag cgcatggatt gaaatattca ataaatcatt cggtagcgcc
     9781 gacctggcag cttgcttgct gaaagtaagc agccaaccgg gcgatacagt tacttatttt
     9841 atcccgaaag gtgatatact aaccttagtg aaaccacgcc aacatgcact attctgggca
     9901 gatggcgaac ctaaccgtgg tactttccat accagcttca agctgaatcc ggaaacagct
     9961 aactgggtgg gtctgttcga ctccggcaaa aagttgctcg accagattgt agtgcccgca
    10021 ggcgcgctcg gtcccaacca atcatacgct cgtgtaagcg acggggcagc tgaatgggaa
    10081 gtaaaaagtg gaagcggtga taaatacgtg actccgagca ccaacaacaa gactcttgac
    10141 agcaattcca agatggaaaa gtttgaagaa cacgatgctg atggcgttgg aatgtccatt
    10201 tctgccatga gcgtagtatt ctgcggattg attcttctct ttattgcttt taagattgta
    10261 ggaaaagtag ctgttaattt gagcaagcgc aacgctatga aatctaaagg cattgacaag
    10321 catgaagcta aggaactgtc acaggctccg ggcgaagtat acgctgctat ttctatggca
    10381 ttacacgaaa tgcaggatga ggtgcacgac gtagaagaaa cggtgctgac catcacccgc
    10441 gtaaaacgca gctactcacc atggagttcg aagatttaca ctttgcgtga aactcctccc
    10501 agaaagtaag tcacctttta aaaagtaaaa acgatgaaag aatataaata taaaatcaac
    10561 ggtaactcat ataaagtaac catcggagat attgaagaca acatcgctca tgtagaagtg
    10621 aacggtacac actataaagt agaaatggag aaacagccga agcctgttgc gaaacccgtg
    10681 acagtacgcc cgatgcctaa tgctcctgct gctcctactc aagtagtgaa accgaccgct
    10741 ccgtctaccg gaaaatcagg agtaaaatct ccgttgccgg gtgtgatcct cgacatcaaa
    10801 gtgaatgtag gcgatactgt aaagaaagga cagaccatta tcatattgga agccatgaag
    10861 atggaaaaca atatcaatgc ggataaggac ggtaagatta ctgccatcaa cgtcaacaag
    10921 ggagactctg ttcttgaagg taatgacctc gtaattattg aataatatgg gagattttat
    10981 aaacttttta ggaaataacc tggccgactt ctggacatac acaggctttg ccaatgctac
    11041 ggtagggcat gtagtcatga ttctcgttgg cttggtattc atctatttgg caatagccaa
    11101 agagttcgaa ccaatgctgc tgattcctat cggtttcggt atattaatcg gtaacatacc
    11161 ttttaatatg gatgccgggc tgaaagtcgg tatttatgaa gaaggttctg tattgaatat
    11221 attgtatcag ggagtgacct ccggctggta tccgccgctc atctttttgg gcatcggcgc
    11281 catgacggac ttctcggcac ttatctctaa tccaaaattg atgctgatcg gtgcagctgc
    11341 acaattcggt atcttcggtg cttatatgat cgcgctagaa atgggcttcg acccgatgca
    11401 agccggtgct attggtatca ttggtggagc agacggcccg acggccatct tcctttcttc
    11461 caagctagca cctaacctga tgggagccat tgcggtgtcc gcctactcct atatggcgtt
    11521 agttccggtg atacagccgc ctatcatgcg tctgctcacc accaagaacg aacgtgtcat
    11581 ccgcatgaaa ccgccgcgtg ccgtttctca cacggagaag gtgattttcc cgatcatcgg
    11641 tttgttgctg acttgtttcc tggttccttc cggtctgcct ttgctgggta tgctgttctt
    11701 cggtaacctg ttgaaagaaa gtggtgtaac tcgccgtttg gctaatactg ccagtggtcc
    11761 gttgattgat acaatcacta tcctgttggg tctgacagta ggtgcttcta cgcaagcttc
    11821 cgaattcctg acgctcgact ctatcaagat ctttgctctc ggtgcattgt catttgttat
    11881 tgcaacggca tccggtgtca tcttcgttaa gatcttcaat atcttcctga agaagggtaa
    11941 taagatcaat ccgttgatcg gtaatgcagg tgtttctgct gttcccgact ctgcacgtat
    12001 ctcgcaagtg attggtttgg aatacgattc gaccaactat ttgctgatgc acgctatggg
    12061 tccgaacgtt gccggagtga tcggttcagc tgttgctgcc ggtatcctgc tcggattctt
    12121 gatgtaagat acaaggaggc tgtttgaaca gttcttaaaa taaaaaataa gactatccta
    12181 aaagccttga atttataaaa atcacctttg ctacattata gtagtaaagg tgatttttca
    12241 ttataaggac ttgctgtaaa aaagactgta gctaccatgc cccatgtatt gtattgcgca
    12301 ctgttgtgtt accttctctt atcattccgt taatctatcc aaaataatct acgaataatt
    12361 cgtaaatata atatttttag taacttgcag cagataagtc aaacaactaa aataaaatat
    12421 tatgaaacgg attatcattc tgttctttct ttgttgtacc attcctctaa tagcgcaaca
    12481 cacagaccct attcaagaag ctatggcaaa ctacgattat gagacggccc tttctcttat
    12541 agctcaaaaa aagactaccc ctcccctgct attacagaaa ggcaaagcgt tgcgtggact
    12601 aggactcacc acagaggcac ttgctaccta tcaagaaatt atctgtaatg atactacaaa
    12661 tactcgtgct ttcattgaag cggccgaatg ttgccgagca ctagctaaat acaatcaagc
    12721 actaaaatat tatgaacatg cactcgatct gaatccggaa aacaaatatg tacgtattca
    12781 atatatcagt ttgcttctct cccaacagaa gtttagcgag gcgcttggtg aaagtagtct
    12841 gatgacagaa aaagacagtt ccgccattgt cctgcatcta caagctcaaa gctttgaagg
    12901 aatgggcgaa cttcttcccg ctgcaggttg ctattacaat atccaggcta aatatcccga
    12961 cgattatctg gctgccagca aactaggcgc tctaaatata tccggttctt atttcgacga
    13021 agccatcgaa gctacagaaa aataccggca aattgacagt accaacattt ccgtcaaccg
    13081 gcagaacgct ttagcatact gcttgaaaca agactacccc actgccatcc aacgttatga
    13141 atatcttgtc agccaaggag acagttcttt tcatacttgt tattatttag gcatcagtta
    13201 ctatgcagca gagaagtact acgaagctca tgattttttg gaagtcgccc gtaaatatga
    13261 tcccaacaat atcaatctcc tttattacct cggtcgcgcc tgttccaaaa cttcttggaa
    13321 aaaagagggc gtagactatc tggaaaaagc cattgatcta tccattccca aagacagcag
    13381 tatgacccgg ctctatatcg ggatgaccga ctgttacaag atggcacaaa tgtacaaaga
    13441 acagattgca tccatcaaag aacgctacca gcggtatgac aaacaaaacc acaaactatt
    13501 gtatgacatg gcctatatat acttctatga cttgaaagat aagaaaaatg cggaacgcta
    13561 tttggaagca ttcctaaaaa cacgtcctaa agacactaaa gaagaagcgg aaatgaacga
    13621 gagaggcgaa cttgttttag gaaaatccaa ttattataat gccgccgcca actggctgaa
    13681 agatattcaa agtaaacaaa aaatagaaga cttctttcaa aattcctctc cacaacttcc
    13741 tctcccaaag aaagataaat agataagaac tataaagcaa ctaaaaggct gctaccggtt
    13801 tatcggtagc agcctttctt ttatttatgg aataatccgg agattattac tgtgccaatt
    13861 tgttgtcaga accgagcaca ttcagaattt tgtgcttgta cagtttttcc atattgtcac
    13921 gagccgggcc aagatactta cgtgggtcga attcagccgg tttttcagcg aataccttac
    13981 gtacagcagc agtcatagcc agacgagagt cagagtcgat gttgattttg caaacagcag
    14041 acttagcagc tttacgcaat tcttcttccg gaatgccgat agcagctttc agtgcaccac
    14101 catatttgtt gatagtttcc acttcttctt ccggaactga agatgatccg tgaagaacga
    14161 tagggaatcc cggaagtttt tccattacag cgtccaatac ttcgaaagcc aatggaggag
    14221 gaaccatacg gccagtcttc gggtcgatgt ggcattgttc cggagtaaat ttgtaagcac
    14281 cgtgagaagt accgattgag atagccaaag agtcgcaacc agtgcgagta gcgaagtcga
    14341 ttacttcttc agggtcagta tatgtgtgat ggtcggaaga aacttcatct tctacaccag
    14401 ccaatacgcc aagttcacct tctacagtta cgtcaaactg gtgagcgtat tcaacaactt
    14461 tcttagtcaa tgctacgttt tcttcgtaag gaagatgaga accgtcaatc atcactgaag
    14521 agaaacctga atcgatacaa gatttgcaag tttcgaatgt atctccgtgg tcaagatgaa
    14581 gaacgatttc cggatgtgcg cagcctaatt ctttagcata ttctacagca ccctgtgcca
    14641 tgtaacgcaa caaagtagcg ttagcatact gacgagcacc tttagaaacc tgaagaatca
    14701 caggagattt agtttcaaca gcagccttga tgatagcctg catttgttcc atattgttga
    14761 agttgaatgc tgggatagca tatccacctt tgatagcctt agcaaacatt tctcttgtgt
    14821 ttaccaatcc taaatctttg taatttacca ttttgtttaa agtttattgt tagtgaataa
    14881 aaattctacg caaaagtaag cattatccat cgaataacga acatcggaaa gaaaaatata
    14941 gtagaaaaag gtttaaatca gacaccattt ttctgcagga atatgagtgt gacattagat
    15001 tgtaatgtct accttgcaaa taaacggata aaagacagta acgcgtattg cttgtatcca
    15061 cgcagtcatt tatatatgaa ttaagagaaa aatcctgtta tatgcaggat atataggtag
    15121 tctgtgcctt atatagttgt ataaaccaat gatgatgaca tacttatttt ataaaacaga
    15181 ttacctttat cgaagttttt tccataaaac ctttttctat ttcacagaaa agcattatct
    15241 ttgcgctctg aaaatgacca ttacactatt tcttaccaaa atagtaacag aatataaatt
    15301 aaaaaaacag atactgaaat gaaaaaaggc cttcatccag aatcataccg tccggtagta
    15361 tttaaagata tgtcaaatgg tgacatgttt ttgtctagat caactgtagc aactaaagaa
    15421 accatcgaat tcgaaggtga aacttatccg ttgctgaaga ttgaaatctc aaacacttct
    15481 cacccgttct atacaggtaa atctacattg gtagatactg caggtcgtgt tgacaagttc
    15541 atgagccgtt acggtgaccg taagaagaaa taattcgatc tttcgtgaaa gatgaaaaaa
    15601 gaggagattc tcgcagagaa tttcctcttt ttcgttttct atattcctta acgtcaagca
    15661 tcatccaaca agaaatcggc tatatgacga tgcctgacac cctccacatt atcctgccac
    15721 aagctgtcca tgctaactac atatttagga taatggtcgt taatggcgag caaaggagca
    15781 aactccctct caacagtggc ctgtgaagct aactgatacg ttacttgcac ataaatcttt
    15841 tcttcccgac ggatggctac aaaatccact tctttatcat cctgtttgcc tacatacact
    15901 tcataacccc ttcttttcaa ctccagacag accagattct ccaacatacc tgcaatcaac
    15961 cggtcacgat agcccatcac ggaataaatc aaagaaaggt cacttacaaa atacttctca
    16021 ttcgtctgca gaatttcctt tcctttaata tcataccggg gaatacgttg aatgataaaa
    16081 gcactttcca atgcattcag ataattatag atggtattca tatccacctt ccgttgctga
    16141 cttttgaagt aatcagctat atttttagcg ttcagcttat tgcctatatt atcaaaaaca
    16201 aacttcacta cccgttcgag caattccaca ttccggatat tgtgacgctg caccgtgtca
    16261 cgaagaatga cagaagaata gatgtcgtag acaattttat agatagcctc atatccataa
    16321 tcggcagtat gtatggccgg aaatcctccc atacggagat atttctgaaa ttcctccttc
    16381 cggttgagcg tcggatcatt ggcctgcaag tcatggaaag tcagatattc tctaaaagac
    16441 aaggtcatga catggaaagc gacataccgt cccgttaaat aagttgccag ttcggacgat
    16501 aacatacgtg agttggagcc ggtcacataa atatccgtat ccaaatctac cagaagtgag
    16561 ttgaccactt tttcccaacc gtccacttcc tgaatttcat ccaagagaat ataatattta
    16621 cccgcatctc ccgcctgtcc ccgaatataa gcatacaaag ccttcgcctc tttcagatct
    16681 atccactgaa aactttcaaa attcagatcg atgatacgtt cttcacgaac tcctctcctc
    16741 aacagttcgt cacgaatcag acgcagcact accgactttc cactgcgacg aatacccgtt
    16801 atcactttta caaacggctt atctataaaa ggaacgattt gttccatata ctgttcacga
    16861 ttaatcatat tcaaaagttt ttagggttat aagcacaaag atatactatt ttcggaaagt
    16921 ttttagggtt ataaccctaa ataaatccat gaattcagat tcttttaggg ttacaagccg
    16981 aaaaataaat aaaagaaata tgactaaatc cgatttatta ccaaataaag aaagtacctt
    17041 tacccgacta attaataaaa aaatggaaat aaccgattta aaacaaatga caaaggaaga
    17101 agtttttaat ttcatcagac aacgcctttc tttcagtaaa gagctgcaag aacaattcag
    17161 acatgtgaat aaagacgatc tcgcaaaaga acatcgcaga ttcgaaatgt ccggaaatga
    17221 atcaaagaca ggccaatgca cgattttcaa cacagcgatt ctgaacgagt ttgccgatct
    17281 tggcatctat gattatactt cttatctttt tctcgacttc cacaatggca ctccaaccgt
    17341 ttatctcaaa tacttctccg aaaatgaaaa tttggaatat acatttaccg gatataccac
    17401 aacggaaatc atctttgcaa ttcttgaact gactatcttc tccggaaagc ccaaaagaaa
    17461 tcgcagctaa aaaaagaatt gcacggaaag acaatgcgag gtcaaaagac ttttatggct
    17521 ttcatttagg cacggattac acgaatttca cggttccatt agactaaaac cgtgaaactc
    17581 gtgtaatccg tgcctaaata atatcaatct aatagatggt tttacttttg gctccctcct
    17641 ttttatcatc acattatatt tgccacccgt atagcatatt taccatcttt ataccatact
    17701 ctctattctc ataccatatt tcctgcattt atttcctctt ttccatccta ttccgaaaaa
    17761 aaaatatatc tttgtcacac gctttctgcc catcagcgtg atgaaacagg caaaagcgtt
    17821 tttttattcc ttaatggagt aaataacgta ttgtctctca aacttaaaaa ttagcagttt
    17881 tttcacaccg agagatgata caacagatac tccacgtaga tagtcgtata tcaacatatc
    17941 gattagagat ttgttatata taaacgtttg gcgtgggtgt ctgttgttta tcattatctg
    18001 gtgaagggtg ttgctaagcc ttaagtttag ataatggtac aacagcactc acgcttttat
    18061 tgtatccggt cggtttcaac aatccttata ccccaaccaa ttccccagcc gaccgaaatc
    18121 ataaaaatcg tgggtgttcg ttgcacctct ccggacaata cgttatttac tcctttttta
    18181 taacacatta aaacaaaagc gatatgccaa aatggattag tgtagaaaaa gcagtgatta
    18241 agtatcacat cgaaaaagaa gcgatcctgc tttgggtgga aatgggacaa ttccctatgt
    18301 tatacataga caatgttccg aatgttgacg aagaatgtat tctggaactc tttcgccgaa
    18361 gtaaagccgg cattacagca gaatatattg atacgctgga acaactgtgc atagataaaa
    18421 caatggtctg cgagaaatac gcccacatta ttcaattgaa agaaaaggaa attcagctgc
    18481 agaaggaaat aaatacgttg ataaacgaaa tacaggcagc aatgaagaga caaaatgaac
    18541 ggatccggga tttgaaaaaa gcgattggag agaataacaa cgttatacgt agtgacagtt
    18601 ggataaaaag gctgcgcaaa aggtttcaat ggtgaataat tatcagtgta ccaattacca
    18661 tgtgggacat tattgcacgg ttttcaccac agaggataaa gagggccgtc ctttgccctt
    18721 tgcagcctat tcccattccc tccacagctt tctttaaact cctccataag ctctttaaag
    18781 cctatattca aacaatgaaa aatacaaaat attttattcc atttatttaa ctaatcatcc
    18841 attatataag taattttatc ctttgtaaag tcaagtaaat tcactacatt tacaccacta
    18901 acaagaactg aaatgtgagc atttcagcac aaagaaatct gtatgaaaaa aacgatgaag
    18961 aatgacagtt gcctgacggt ttcccgtcgg gcagctatta tccgccaaga tgcggaagag
    19021 aattacggca cactgttgac actgggagaa tctatgcgcc gtgcatacca agtagaagaa
    19081 ctgatagacc ggatgagatg ggacaacgcc gatttctgcc tgcaacgaac agacggaacc
    19141 tgcctttcca ttacagggac actgacagaa tatgaacact atttcggccg cccctactac
    19201 gaaaacccct ccaacaggtt tctcccatac tatgacgtgc attgtagaaa atggcttacg
    19261 tgtcgagtgg cagggattgt attcggctct tctgtgaaaa aaaattaatt tcatggatta
    19321 aataaggaaa gttgtaggac atatacgaaa taaagtagtt actttgcaac cgcaagtaag
    19381 agaaaaaatc atgtcaatgc tgcttccttg ttttttgaca gaggcagtta tctgtttttc
    19441 cagcattgct ttttcagaac ttcggaatta aatctcccct gctccgaaaa ttccctatat
    19501 tacagattac atacacgaag agaatactcc gattccatca tgaagaatga gtacgatatt
    19561 tgctactttc caaagaagtg gccggattct tcgtatctgt attttcagaa aaatagaatt
    19621 taaaacagaa actaatatat tttattatga caacatctaa ttcagcaaat accaaacaat
    19681 cgaacaacgc atcacaaaag agaaaaccga ttcataacgg ttacttcaat catcccactt
    19741 cttcttccag caatataccc atgagtattt tgatacggga acaaggactg gaaatatacg
    19801 gactatactg ggtgatgctc gaagaagctc atgcacagct taaatgctgc gtcaatatcc
    19861 agacaatggg aatcatcgcc aatatattcc atgcccaacc cgaacatctt gagctcctct
    19921 accaccatta tttccggcgt cctggtaaag gatacaactc gcatatactc tatgccgact
    19981 tttgcgaaga atctgccatc agaagttatt tcccgcaccc cctactggca tacaccgaca
    20041 acgaactgct gcggatgatt atgcaagacg gactgaaagc ctacggacta tattggcttg
    20101 tgatggaaaa gctctatcaa cagccacaac attttctggc accgcaaact gcttccttca
    20161 tccagaacct ttatgatgtg agcgacgaac tgatggaaag tgtattatac aattacggac
    20221 tcttttatct ggatgagaaa atgaacctcc attctaaagc aatagacgat tatagggaag
    20281 cacttgacaa catggaagat gaaaaaaagc gcaacacgaa accgcacgtc aataactctc
    20341 tgaaagccaa cggaaatgca gaggatttta acactcggga aatgaaaaaa acgtcaaata
    20401 tacagaaaaa tccatccccc attataaata aagaaataaa caaaaaaaat tcttcttctg
    20461 aagaaagcgg aaaagaaaaa gaagaagaaa atggtttgaa ggtgacggac ttgaacgctg
    20521 tgacacccga tatgcgcccc aacgcatggg aagaaaatct acaggaggca atgaacgaca
    20581 cgtcctggta tgaagtcgta gccattcagt cgggcatccc ccggctgatg atggaagaaa
    20641 aagaatggtt cttcaactat ttacgggagc aaatcatctt acgggggaat gaaagctcga
    20701 tgaacagcct gcacgaaata aaaaactatt tcgccaatct cacccggcag ggaagccatg
    20761 tgtcatccac aacgcaggtg gcactgaaga agtttctcaa aaaccggcaa gagcaacagc
    20821 aatgttcgcc ctacgaaacc atcaccaacg gaatacgtac ctacgacggg catcccatcc
    20881 ccgcttatgc caagccgcga ccttcggcgg cacatatctg gaatccggtg acgaacgaat
    20941 ggacacgata gcatattatc tctcaatcat ttactaaata tggatagatt caaagaactg
    21001 ggtattgata cccacggtcg cacaagcggc aaaatgaaaa caaaatgtcc ctggtgtcat
    21061 gcccaacgga cggataagcg tgataaatca ctaagtgtca acctcgatac caaactgtat
    21121 ttgtgccact actgcggcgc acacggttcg gcagccatat atgccggaaa aggcagaaag
    21181 ctgggtgatc cgttggtcaa atttccaacg gcaacaggta gcaactccag ttgtccgccc
    21241 actgaaaagc cgcacggcga cccagagcaa ggggcactca cacagaagca aattgaatgg
    21301 tgtcgtgacg tccgccacat tccgccggaa gtattggtgg aagctggcgt ggctttcgcc
    21361 tccatctcga tgcctatatc cggaaaggag aaaggctggg aaaagaggga ctgtctctgc
    21421 ttcaactttt tcgaaaacgg ggaattggtg aacacaaagt tccgcgactc acaaaagcac
    21481 ttcaaattgc tgcaaggagc gcgcaccatc ccttacaaca tcgacgccat ccgcgacacg
    21541 ccggagtgca tcctcgtgga aggggaattt gatgccctct cctacatggc tgtcggccgg
    21601 acggatgtca tttccgtgcc gaacggtgcc aacagtcaac tggactggct ggacgaattg
    21661 tcggaatctc atttcgagca gaaacaagtg atttatctgt cggtggacac cgaccgcaag
    21721 ggacgggaac tgtgccggga actctcccga cggctggggg tagaccgctg ccgtatcgtc
    21781 acctacggcg aagcatacaa ggacgccaac gaactgctcg tggcggaagg cccggacgca
    21841 ctactgaagg cactggagga cgcacccatc ccccgcctgg aaggtacgtt tacggcagaa
    21901 gacttacggg aggggttgca ccaactgttt gaagaggggt atacttcggg cgtggaattg
    21961 ggaataccga atctggacga aatcatgagg ctggaaacgg ggcgagtgct caccgtcacc
    22021 ggtattcccg gacatggcaa atcggacttt gtggatgaga tagtgctccg gctctgcacc
    22081 cgccaagatt ggcgagcggg atatttcagt ccggagaaca cgccaat
//
