LOCUS       c00357_gnlPro..        12818 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AOHAKLKG_357.
ACCESSION   c00357_gnlPro..
VERSION     c00357_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:52:51
            Original ID  :: gnl|Prokka|AOHAKLKG_357
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12818
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12818
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3586:8295]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3587..8295
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..12818
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12818
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(102..1952)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg357_1"
                     /sec_met_domain="Alpha-amylase (E-value: 2.9e-64, bitscore:
                     207.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVFLILGTLLLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNAAVSVNYPGVSLSSTVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKE
                     YELKARNKKGCEHKGFDASDALYLLMPDRFANGNPDNDQIAGMAEYKIDRNDPNARHGG
                     DLAGIEQHLDYFSDLGVTALWFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQL
                     IEKAHARGIKIVMDMIFNHCGVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPY
                     TSQYDADQMNDGWFVPSMPDLNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKI
                     NTAKNEQTETWFKGLDRIYNNFVYDFLYPNPASVLAFIENHDTDRFLGEGDNLPMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNE
                     CYDFYKTILNWRKGNDVIAKGSMVQFMVQNGVYAYARQYEGKTVFVMLNGTDAETTVPL
                     KFYKEILKNSKQGKDILSGKAITFGEELKMGPRESLVIEL"
     CDS             complement(2062..3414)
                     /locus_tag="ctg357_2"
                     /transl_table=11
                     /translation="MRKLFISLCFSACCSLLAAQTTNPIQEAMANYDYETALMLIDQET
                     PTVPLLYQKGKALKGLGNNLEALSVFQEVVAQDSLNPRAYIEAAECCKSLAKYSEALDY
                     YQNALHINPDNKYARIQYISLLMNMKRYRESLKESNLLAERDSSAYVLHLRAESMGQVY
                     DNTEIMHVIDAYLDIQKRYPNDYLSAAKLGNIYVAGHQYEDAINITEKYRSIDSTNVLV
                     NRINAQAYCLNKDYPKAIERYEQLLQEKDSSFQTCFYAGISYYALEDFYPAHDLLERAL
                     KDDNTNINVLYYLGRACSKTSWKEDGVTYLETAVSLAMPSDSVMSRLYVGLADCYKMAF
                     QYTDQANTLLTQYEKYDRQKHKLLYDAAFIYYYYLKDASKAERYLTAYLKTRPKNSKDK
                     VQEVDADGVPIIGEDNRYNAAENWLKDIREKRKKEDFFKGKVDTASVTPIK"
     CDS             complement(3587..4747)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg357_3"
                     /sec_met_domain="OAD_beta (E-value: 3.9e-153, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(4749..5183)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg357_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.4e-22, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             complement(5207..6139)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg357_5"
                     /sec_met_domain="OAD_gamma (E-value: 8.4e-18, bitscore:
                     54.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             complement(6171..7724)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg357_6"
                     /sec_met_domain="CT_Btheta (E-value: 1e-291, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             complement(7783..8295)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg357_7"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3.2e-26, bitscore:
                     81.2, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFFIKEEFSFFVLLYTFIKKDTILTLIYIVMKISHIEHLGIAV
                     KSIEEALPYYENVLGLKCYNIETVEDQKVRTAFLKVGDVKIELLEPTSPESTIAKFIEK
                     NNGNGGMHHLAFAVEDGVAGALAEVEEKGIRLIDKAPRKGAEGLNIAFLHPKSTLGVLT
                     ELCEKPE"
     CDS             8489..9976
                     /locus_tag="ctg357_8"
                     /transl_table=11
                     /translation="MKKNILLAVCFLMPLATMAQNDTLGHERNITLSEAIVLARTQSVD
                     AAVALNELKTAYWEYRTFRADLLPEVNFTGTLPNYNKSYSTYQNSDGSYSFVRNNTLGL
                     SGQLSVDQNIWFTGGKLSLTSSLDYLKQLGSGGAKQFMSVPVSLELTQPVFGVNTLKWN
                     RRIEPVRYAEAKAEFISATEEVTMKTITYFFELLLAKESLATAMQNKTNADRLYEVAIA
                     KRKMGQISENDLLQLKLNSLQGKADVTEAESNLNAKMFQLRSFLGVSEQESLNPVLPAT
                     VPDIKMEYDRVLNKALERNSFAQNIRRRQLEADYEVATARGNLRSIDLFASVGYTGQNH
                     EFSSAYRDLLDNQIVQVGVKIPILDWGKRRGKVRVAKSNREVVLSRIRQEQMDFNQDIF
                     LLVANFNNQAQQLDIAEEADVIAEKRYKTSVETFMIGKISTLDLNDAQNSKDEARQKHI
                     SELYYYWYYFYQLRSLTLWDFERDTELEADFEEVVRG"
     CDS             10120..11481
                     /locus_tag="ctg357_9"
                     /transl_table=11
                     /translation="MILIIDDDSAVRSSLSFMLKRAGYEVKTAPSPREAMDIVRAEAPA
                     LILMDMNFTLSTTGEEGLTLLKQVKVFRPDVPVILMTAWGSIQLAVQGMQAGAFDFITK
                     PWNNAALLQRIETALELTAAPKEVPEEQTTALNRSHIIGKSKGLMEVLNTVARIARTNA
                     SVLITGESGTGKELIAEAIHINSQRVKQPFVKVNLGGISQSLFESEMFGHKKGAFTDAS
                     ADRIGRFEMANKGTIFLDEIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKVDVRVVSAT
                     NADLRKMVSERTFREDLFYRINLITVKLPSLRERREDIPLLARHFADRQAEVNGLPRTD
                     FSADALNFLSRLPYPGNIRELKNLVERTILVSGKPVLDATDFDAQYLRHDEPAKVAEGT
                     SFAGMTLDEIERQTILQALEQHKGNLSQVAVSLGISRAALYRRLEKYNIQVPCA"
     CDS             11472..12785
                     /locus_tag="ctg357_10"
                     /transl_table=11
                     /translation="VRIKFFFFILVLFLLGLGGMLVYLLSGKPLLYLYVLEGLIGFILI
                     YLIVFYNKIVKPMNTIGSGMELLREQDFSSRLSRVGQYEADRIVNIFNRMMEQLKNERL
                     RMREQNHFLDLLIQASPMGVIILTMDDEVSQLNPMAVKMLGVRMEEAMAKRLDQMDSPL
                     AAELSSIPKDETAVVRLNDANIYKCTHSSFIDRGFKHPFFLIERMTEEVMRAEKRAYEK
                     VIRMIAHEVNNTTAGITSTLDTVEQALSTEDDMEDICDVMRVCTERCFSMSRFITRFAD
                     VVKIPEPTLVPVQLNELVSMCKRFMEGMCNDRNIELRLECDPEVGMVRMDASLFEQVLV
                     NIIKNAAESIEGDAGENGQQGEIIVRTTAPASVEVVDNGPGISKETEAKLFSPFFSTKP
                     NGQGIGLVFIREVLSRHGCTFSLRTYNDGLTRFRILFN"
ORIGIN
        1 ttccatacta aaaatccctt gcagatggct ggcaggagaa gtgtctgcca gctatctgaa
       61 agggagattt gcaagaatgc gctctctgtg tggagtgcgc gttataattc tatcactaat
      121 gattctctgg ggcccatctt cagctcttca ccgaaggtga tggccttgcc gctaagaata
      181 tcttttccct gcttgctgtt tttcaggatt tccttgtaga atttcaaagg aacggtggtc
      241 tctgcatctg taccgttcag catcacgaat accgtcttgc cttcgtactg gcgtgcgtag
      301 gcataaacac cattctgtac catgaactgc accatgctgc ctttggcaat cacatcgttt
      361 cctttgcgcc agttcaggat ggtcttgtag aagtcgtagc actcgttctg tattttggta
      421 cgtccggctg gggtcagtgc gtttgttgcg tcaccggtcc atccaccggg gaagtccttg
      481 cggacatagc cgtcgctctt gctcttcacg ccattcatca taacttccgt tccgtagtag
      541 agttgcggaa tgcggcgggt ggtaagcagc agggtagagg cttgcttcag catcggaagg
      601 ttgtcgcctt cgcccaggaa gcggtcggtg tcgtggtttt cgatgaatgc cagtacggaa
      661 gcggggttgg ggtagagaaa gtcgtatacg aagttattgt atatgcggtc cagtcccttg
      721 aaccaagttt cggtctgttc attcttggcg gtgtttatct tgtcgaagaa gctgaagtcc
      781 ataacggtct tgaggttact gttcttgggg gctgatagct tggaatcctt ctgccaccag
      841 gcggtgtagg cgggttcggt aacccaggtc tcgcccacgg tgttgtagtt gggatattct
      901 tcgttgagct ctttcatcca gttgctcatg gcatcatagt cggcatacgg gtaagtgtcc
      961 atgcggatgc cgtcgatgtt ggcgaattca atccaccaga aactgttctg taccaggtag
     1021 cggtaaacgt gagggttctt ctggttgagg tcgggcatgg aaggtacgaa ccagccgtcg
     1081 ttcatctggt cggcatcgta ctgggaagta taagggtcta cgtgcggggt cagtttgaag
     1141 gaggtctgca cgaagttgtt ttcgtggtcg gggttgttga accaatcttt ggagggcatg
     1201 tccttaatcc atacatgctc tacgccgcag tggttgaaaa tcatgtccat tacgattttg
     1261 atgccgcgtg catgggcttt ttcaatcagt tgcttgtatt cttcgttggt accgaagcgc
     1321 gggtctacct tgtagtagtc tgtggtggca tagccgtgat aggaaccgcc ggtcatgttg
     1381 ttttccagta ccggagtaaa ccagagggct gtgacgccga ggtcggagaa gtagtccagg
     1441 tgttgttcga tgccggcaag gtcaccgccg tggcgtgcat tggggtcatt gcggtctatc
     1501 ttgtactcgg ccatgcccgc aatctggtca ttgtccgggt tgccattggc aaagcggtcg
     1561 ggcatcagca ggtacagtgc gtcggaggcg tcgaaacctt tatgttcgca acctttcttg
     1621 ttgcgtgcct tcagttcata ttcctttacg agtttctttt ttccttcagt gaaggtgagg
     1681 ttgaatttgc cgggttttac atccttgtcc agtttcagat agaccaggag gtagttgttg
     1741 ctttccagct tgacggtgct gctcaatgag acgccgggat aattgacgga tactgccgcg
     1801 ttgccgatgc cttcgccata gaccatcagc tggagttccg ggttctgcat gccggtgtac
     1861 caaaacggag ggtcgatttt gttcacattc atagctgcat acgtactgag ggagagtaag
     1921 agtgttccca agattaagaa tacttttttc atgatagtaa ctttacggtt aatttttgcg
     1981 ctaatttaaa acaaataacg gagaaagtta atctttctcc gttactgtac tttattatat
     2041 tatgcaaacg ttttcattgg gctatttgat gggggttacg ctggcggtat cgacctttcc
     2101 cttgaagaag tcctctttct tgcgcttttc tctgatgtcc ttcagccagt tttcggcggc
     2161 attgtatcgg ttgtcttctc cgatgatggg aactccgtcc gcatctactt cctgcacttt
     2221 gtccttgctg tttttcggac gggttttcag gtaggccgtt aggtatctct ctgctttgga
     2281 cgcatctttc agatagtaat aatagataaa ggctgcgtcg tagagcagtt tgtgtttctg
     2341 ccggtcgtat ttttcgtatt gtgtcagaag ggtattcgcc tggtcggtgt attgaaatgc
     2401 catcttgtag cagtccgcaa gccccacata taggcgggac atgacactgt cgctgggcat
     2461 ggcgaggctt acggcagttt ccagataagt cactccatcc tctttccatg atgtcttgga
     2521 gcaggcgcgt cccagataat agagaacgtt gatgttggta ttgtcatctt taagagccct
     2581 ttccagcagg tcgtgtgctg ggtagaagtc ttcgagggca taataactga ttccggcgta
     2641 gaagcaggtt tggaaagaac tgtctttttc ctgtaacagt tgttcatatc tttctattgc
     2701 tttggggtaa tctttgttca ggcaataggc ttgggcattg atgcggttca caaggacgtt
     2761 ggtggagtct atggaacggt atttctccgt tatgtttatg gcgtcttcat actggtggcc
     2821 tgctacatag atgttgccga gtttggcagc agacaggtaa tcattgggat atcttttctg
     2881 tatgtccaga taggcatcta tcacatgcat gatttctgtg ttgtcataga cttgccccat
     2941 actttcggct ctaaggtgta gtacataggc ggaactgtcc ctttctgcca gcaggttgct
     3001 ttcctttaga gactcacggt atctcttcat gttcatcagc agactgatat actggatgcg
     3061 tgcgtattta ttgtccggat ttatgtggag cgcattctgg tagtaatcca gtgcctcgct
     3121 atatttggct agtgatttgc agcattcggc agcttcaatg tatgcccggg gattgagaga
     3181 atcctgagct acgacttctt gaaatacgct cagagcttca aggttattgc ccagtccttt
     3241 cagcgctttc cctttttggt agagcagggg gacggtcggg gtttcttgat cgatcaacat
     3301 caaggctgtt tcataatcgt agttggccat cgcctcttga atggggtttg tggtctgtgc
     3361 cgccagaagt gaacagcatg cactgaaaca taaggagata aaaagctttc gcatacagta
     3421 tatcatttat atgaggttaa actgactgca agttactaaa aagaatgtat ttacgaaata
     3481 atcgtaattt gttttagata gattaacgaa aaagcccctc caaaaatgat ggaggggctt
     3541 taaaatagtt cggaattcaa tccggataac ggaatgaata aatgtattac attaagaatc
     3601 ccagcaggat acctgctgct acagcggaac cgattacacc ggcaacgttc gggcccatgg
     3661 catgcatcag cagatagttg gtaggatcgt attccagacc tactacttgg gagatacgtg
     3721 cagagtcggg tacggcagat acaccggcat taccgatcaa cggattaatc ttgttgcctt
     3781 tcttcaggaa gaggttgaaa atcttcacga agatgacacc ggatgctgtg gcaatgacaa
     3841 atgataaggc gcccagaccg aatatcttga ttgaatcaag ggttaagaac tcggatgctt
     3901 gcgtagaagc acctactgtc aaaccaagca gaatagtaat ggtatcaatc agcggaccac
     3961 tggctgtgtt tgccagacga cgtgtaactc cactttcttt cagtaaatta ccgaagaaca
     4021 gcatacccag caaaggcaga ccggatggta caaggaatgt ggtcagtaac aaaccgataa
     4081 tcgggaacat tactttttcc gtatgtgaaa ccacacgggg aggtttcata cggataagac
     4141 gttcattttt actggtcagc caacgcataa taggcggctg tatcaccggt actaatgcca
     4201 tatatgaata ggctgatacc gcaatggcac ccattaagtt aggagccagt ttggaagaga
     4261 ggaagatggc agtcggacca tcggcaccac caatgatacc gattgcacca gcctgcatcg
     4321 ggtcaaatcc tatggcaagg gcaatcatat aagcaccgaa tataccgaat tgggctgctg
     4381 caccaaccaa cattaatttg gggttcgata tcaaagcaga gaaatccgtc atggcaccga
     4441 tacccaggaa tatgagtggc gggtaccaac cggaggttac tccctggtac agaatattaa
     4501 gtacggaacc ttcttcatag ataccgactt ttaatccggc ttccatattg aaaggtatat
     4561 taccaatcag cataccgaaa ccgataggaa ttaatagcat cggctcaaat tccttggcta
     4621 cagccaagta tatgaaaaac aaacctacca gaagcattac cacatgtcct accgttgcat
     4681 tggcaaaacc tgtataagtc cagaagtcgg caaggttgtt tcctaaaaat gtgataaatt
     4741 ctcccatatt attcaataat tacgaggtca gtaccttcga gaacagagtc ccctttgttt
     4801 acattgatgg ctgtaatctt accgtcttta tcagcattga tattgttttc catcttcatg
     4861 gcttccaaaa tgatgataac ttgtcccttc tttactgtat cgccgacatt tactttgata
     4921 tcgaggatta caccgggaag cggagatttt acacctgact tgccggtaga agcagcggcc
     4981 ggttttacta ccggagtagc aggagcagca ggagcggatg tggctgccgg acgtgctacc
     5041 ggtttaacaa ctaccttcgg tgctttttcc atttcaactt tgtagggagt accgttcact
     5101 tctacatgag cgatgttgtc ttcaatatct ccaatggcaa ctttatatac gttaccgtta
     5161 attttatatt tatattcttt catcgtttta ttttattatg ggtgacttac tttttgtgag
     5221 gagtctcacg caacgtataa atctttgaac tccacggtga gtaactgcgt tttacacggg
     5281 taatggtaag tatcgtgtct tccacatcgt gtacatcgct ttggaattcg tgcatggcca
     5341 ttgaaatggc agcaaaaact tctcccggag cctgccccag ttgtttctct tttgcttctt
     5401 gtttatcagt aataccttta gctttcatgg cattgcgttt gctgaggtta actgatattt
     5461 tacctataat cttgaaggag atgtagagta atatcagccc gcagaataca acgctcatgg
     5521 cagaaatagc cataccgata cctacgctgt catgctcttc gaatttttcc attttggcat
     5581 tgctgtcgat agtcttgttg ttggtactcg gagtgacata tttatcttcg cttccaccct
     5641 ttacttccca ttggtcggct gcatcactga cacgggcata ggattggttg gcttttaaag
     5701 taccggcagg cactatgact tgatcaagca atttcttgcc ggaatcatac aacccaatcc
     5761 agttggcatt tgtggcatcc agtttgaagt tcgtatgaaa tgtaccgcgt cttggttctc
     5821 catcagccca gaaaagtgca tgctgacgtg gttttatgag tgtcagaacg tcacctttgg
     5881 gaatgaaata actggcagta tcacccggct ggctgctgaa tttcagatag caacctgcaa
     5941 ggtcggcgct gccgtatgat ctgttgaata tttcaatcca tgcgctgtgc acaccgtagt
     6001 catcctgata gttgctttcg ttgttgacca gcacttcatt cagcagcagt ttgttgttcg
     6061 atttctgttc tttgcaagaa gagcaaaagc ctaacaccag catcaatgaa aggaatattc
     6121 cgatttttgt tttattcata atcgttcttg ttttagtgtg aaaagcttga ttacaaggga
     6181 atattaccat gcttcttagc cgggttagtc aatttcttgg tttgcaactg ttgcagggca
     6241 cgaatgatgc ggaaacgtgt gttacgcggt tcgataacat catcaatgta gccatattta
     6301 gctgcattat aaggattggc aaacaacttg gtgtattcag cctctttttc agccaggaat
     6361 tgagccggat tttcctgctc tttggcttcg cgggcatata atacttctac agcacctgca
     6421 ccacccatta cagcgatttc agcagtaggc caagcataat tcatgtcgcc acgcagctgc
     6481 ttacagctca tcacgatgtg cgaaccaccg taggatttac gcagtgtgat ggtaaccttg
     6541 ggtacagtag cttcaccgta tgcatacagc agtttggcac cgtgcaggat gacgccgttg
     6601 tactcctggc cggttcccgg aaggaatccc ggtacgtcta ccaatgatac gataggaata
     6661 ttgaaggcgt cgcagaaacg gacgaagcgt gcgcccttgc gggatgcgtt gctgtcgagc
     6721 acacctgcca gatacttcgg ctggttggca acaataccta cggactgtcc gttgaaacgt
     6781 gcgaaaccaa taatgatatt ctttgaataa tctttttgga tttcgaggaa ctcaccatta
     6841 tctatgatag cgccaattac ctcgtacata tcgtacggtt tgttcgggtt atcaggaatg
     6901 atgtcgttca gggaatcttc cagacggtcg atagggtctg tgcagtctac ataaggagct
     6961 tcttccaggt tgttctgggg aatgtagctc aacagtttgc ggataagggc caaaccttct
     7021 tcttctgtct gtgcagtaaa atgagtaaca cctgatttgg tggagtgaac gctcgcgcca
     7081 cccaggtttt cctggcttac gtcttctccg gttacagtct ttactacctt cggaccggta
     7141 aggaacatgt aggatgtacc ttccatcatc agcgtaaagt cagtcaatgc aggagagtaa
     7201 acggcaccac cggcacaagg accgaaaata ccggaaatct gcgggatgac accggaagca
     7261 aggatgttac gttggaagat ttcagcgtag ccagccaagg cattgatacc ttcctgaata
     7321 cgtgcaccgc ccgagtcgtt gataccgata cacggagcac ccattttcat ggcttggtcc
     7381 ataatcttac agattttcag agacatggtt tcggacagtg aaccggcgga aacagtgaag
     7441 tcttgtgcaa agatataaac cagacggccc tcgattgtac cgcaaccggt taccacaccg
     7501 tcaccggggt agtgtttctt ttccatgccg aagttcgtac atctatgttc tacgaacatg
     7561 tccatttctt cgaaactgcc ttcgtcgaga agcatggcta tgcgctcgcg agctgtatat
     7621 ttacccttct cgtgttgctt tgcaatcgct ttttcaccac caccgagacg tgctgcagcg
     7681 cggcggtcta taagctcttt aatcttttca agttgattac tcatgaattt atattcttta
     7741 agtgtttata caatttatga tttgatgatt ttacagtctt gcttattccg gtttctcgca
     7801 aagctcggtc aggacaccga gagttgactt cggatgcagg aatgcaatgt tcagaccttc
     7861 tgcacctttg cggggagctt tgtctataag gcggatacct ttttcttcga cttcggcaag
     7921 cgcaccggcc actccgtctt caacggcaaa tgccagatga tgcatgccac cgttaccgtt
     7981 gttcttttcg atgaacttgg caattgtgct ttcgggagaa gtaggttcca acaattcgat
     8041 ctttacatcg cccactttca ggaaagcggt tctaactttc tgatcttcca cggtttcgat
     8101 gttgtagcat ttcaaaccta aaacgttttc gtagtacgga agggcttctt caatgctctt
     8161 aacggcaatg cccagatgct caatgtgtga aatcttcata actatataaa ttaatgttag
     8221 tattgtatcc tttttaataa aggtataaag cagcacaaag aaagagaatt cttccttaat
     8281 aaagaaattt ttcatcaatt aattaatggt taattgaact ttagaaggat tttttcagac
     8341 tttagataga gaccggttgt tttcttgata tcgtccgcta acggacatcc ccactgtccg
     8401 aaaatgaaca cttacccctc tatgaaacct ttccggccac ttggcacact ctttgctttt
     8461 ctgtttgcga caattttaaa gattgaacat gaaaaagaat attttacttg cagtttgttt
     8521 tttgatgccg ttggcaacca tggcgcagaa tgatactttg ggacatgaac gcaatattac
     8581 gctgtcggag gccattgtac tggcccgtac gcagtctgtg gatgctgctg tggcattgaa
     8641 tgaattgaaa accgcgtatt gggaataccg tacattccgt gcggacttgt tgccggaagt
     8701 gaatttcacc ggtacactac ccaactataa caagtcctac agtacctacc agaattccga
     8761 cggctcctat agctttgttc gcaacaatac actggggctg tccggacagc tttcggtaga
     8821 ccagaacatt tggtttacgg ggggtaagct gtcactgact tcttcgctgg attatctcaa
     8881 acaactgggt tccggaggag cgaagcagtt catgtcagtc cccgtgagcc tggagttgac
     8941 gcagccggtc ttcggagtga ataccttgaa gtggaaccgc cgtatagagc ccgtacgcta
     9001 tgccgaggca aaggccgagt tcatttcagc tacggaagag gtgacgatga aaaccatcac
     9061 ttatttcttt gagttgctgc tggccaaaga atcgctcgct accgccatgc agaacaagac
     9121 gaatgccgac cgcctttatg aagtggccat agccaaacgt aaaatgggac agatatccga
     9181 gaatgatttg ttgcagctta aactgaattc attgcagggc aaggccgacg tgactgaggc
     9241 agagagcaac ctgaatgcaa aaatgttcca gctccgttct ttcctcgggg tgtccgagca
     9301 ggaaagcctg aatccggtgt tgcccgccac tgttcccgat ataaagatgg agtatgaccg
     9361 tgtgctgaac aaggcactgg aacgcaactc ctttgcacag aacattcgcc gccgccagct
     9421 cgaagctgat tatgaagtgg caacggcacg cggaaacttg cgcagcatcg acctctttgc
     9481 cagtgtgggc tatacggggc agaaccatga attctcttca gcctaccggg acttgcttga
     9541 taatcagatt gtgcaggtag gcgtcaagat tcctatcctt gactggggca agcgccgcgg
     9601 caaggtaagg gtggcaaaga gcaaccgtga agtggtcttg tccagaatcc gtcaggaaca
     9661 gatggacttt aatcaggaca tctttttgct ggtggctaac ttcaacaacc aggcgcaaca
     9721 gctggacata gccgaagagg cggatgtcat tgctgagaag cgttacaaga ccagtgtaga
     9781 gacctttatg ataggtaaaa tcagcaccct ggacctgaac gatgcacaga actctaaaga
     9841 cgaagcccgt caaaagcata tttcagagct gtactactat tggtattact tctatcagct
     9901 ccgcagcttg accctttggg attttgaacg cgatacggaa ttggaagctg attttgaaga
     9961 ggtggtaaga ggataagtcg acgggttgca agtgataagt tatgagttat ttgccggtaa
    10021 aagtaccgta tatgcgatat tataggtaaa taacttataa cttatcattc ataactctgc
    10081 ttttttactt atttttgcgg gaaacaaact acaattttta tgatactgat aatagacgac
    10141 gatagtgctg tgcgctcttc cctcagcttt atgctgaagc gtgccggata tgaggtgaaa
    10201 acggctccaa gtcctcgcga agctatggac atagtgaggg ccgaagctcc cgccttgatt
    10261 ttgatggata tgaacttcac tctttccact accggagaag agggacttac cttattgaag
    10321 caggtaaagg tgttccgtcc cgatgtgccc gttattttga tgacggcatg gggaagtatc
    10381 cagcttgccg tgcagggtat gcaggccggc gcattcgatt tcataaccaa gccttggaac
    10441 aatgctgctc ttttgcagcg catcgagacg gcccttgagc ttacggccgc cccgaaagag
    10501 gtgccggaag agcagactac cgcattgaat cgcagccata ttataggtaa gtccaaaggg
    10561 ctgatggaag tgctgaacac agtggctcgt atagcccgta ccaatgcttc ggtgctgatt
    10621 acgggcgaaa gcggaacggg caaggagctg attgccgaag ccatccatat caacagccaa
    10681 cgcgtgaagc agccctttgt caaggtgaac cttggtggca tctcgcagag cttgttcgag
    10741 agcgagatgt tcggccataa gaaaggggcg tttaccgatg ccagcgccga ccgtataggg
    10801 cgttttgaaa tggcaaataa aggtactatc ttcctcgacg agattggtga cctcgaccct
    10861 tcctgccagg tgaaactgct gcgcgtgctt caagaccaga cattcgaagt gctgggcgat
    10921 agccgtcccc gcaaagtcga tgtacgcgtt gtgtccgcca ctaatgcaga cctccgcaag
    10981 atggtgtccg aacgtacttt ccgtgaagac cttttttacc gtatcaacct gattaccgta
    11041 aaactgccct ccttgcggga gcgccgtgaa gatattcctt tgctggcacg tcactttgcc
    11101 gaccgtcagg cagaggtgaa cggcttgccg cgtacggatt tctcggccga cgctctgaat
    11161 ttcctttccc gcctgcctta tccgggcaac attcgtgagt tgaagaatct agtggagcgt
    11221 accattctgg tcagcggcaa gccggtgctg gatgccacgg atttcgatgc ccaatatctg
    11281 cgtcacgacg aaccggccaa agttgccgaa ggtacttctt ttgcaggtat gaccttggat
    11341 gaaatagagc ggcagactat cttgcaggcg ttggaacagc ataaagggaa tctcagtcag
    11401 gtggcagtgt cattaggcat cagccgcgct gcgctttaca gacgtttgga aaaatataat
    11461 attcaagtcc cgtgcgcata aaattctttt tcttcatact tgtccttttt ctgctcggtc
    11521 tgggtggaat gttggtatat ttgctgagtg ggaagccgct tttgtatctg tacgtattgg
    11581 aggggctcat cgggtttatc cttatctatc tgatagtatt ctataataag atagtgaagc
    11641 cgatgaacac cataggcagc ggtatggagt tgctgcgcga gcaggatttc agtagtcgtc
    11701 tcagccgggt agggcagtac gaagcagacc gcattgtgaa tatctttaac cgaatgatgg
    11761 agcagctcaa gaatgaacgg ttgcgcatgc gcgagcagaa tcacttcttg gatttgctga
    11821 ttcaggcatc tccaatgggg gttattatcc tgacaatgga cgatgaagtg tcgcaactga
    11881 atccgatggc ggtaaagatg ctcggtgtcc gtatggagga ggcgatggca aagcggctgg
    11941 accagatgga ctccccgttg gctgccgaac tttcgtccat tcccaaagac gagacggcag
    12001 tggtccgtct caatgacgcg aatatttata aatgcaccca ttcttctttt attgacagag
    12061 ggttcaaaca tccttttttc ttgatagagc gtatgacaga agaagtgatg cgtgccgaga
    12121 agcgtgccta tgaaaaggta atccgcatga tagctcatga agtgaacaat accactgcgg
    12181 gcatcacttc cacactcgat acagtggagc aggcactttc tacagaagat gatatggagg
    12241 acatctgcga cgtgatgcgc gtctgtacgg agcgttgttt ctcgatgagc cgtttcatta
    12301 cccgttttgc agatgtggta aagatacctg aacctaccct ggtgcccgtc caactgaatg
    12361 agttggtgtc catgtgcaag cgttttatgg aaggaatgtg caatgaccgc aatatagagc
    12421 tacgtctgga atgcgacccg gaggtgggaa tggtgcgtat ggatgcttct ctttttgagc
    12481 aggtgcttgt gaatatcatc aagaatgccg ccgaaagtat agagggggac gccggagaaa
    12541 acggacagca aggtgagata atagtaagga ccactgcccc cgcttctgtc gaagtcgttg
    12601 acaatggtcc ggggataagt aaagagaccg aagctaaact cttcagtccc ttcttttcca
    12661 ccaagccgaa cgggcaggga attggcctgg tgtttatccg ggaagttttg agccgtcatg
    12721 gttgcacgtt ctccctacgt acctacaacg atggattgac ccgcttccgt atactattta
    12781 attgaaattt gaaagtttta cctttcacct ttcaattt
//
