LOCUS       gnlProkkaNIILIAEK_69    3296 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NIILIAEK_69.
ACCESSION   gnlProkkaNIILIAEK_69
VERSION     gnlProkkaNIILIAEK_69
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 01:05:10
            Original ID  :: gnl|Prokka|NIILIAEK_69
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3296
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..69)
                     /locus_tag="ctg69_1"
                     /transl_table=11
                     /translation="MINEEIIEKIRTTLAEEFEIDVE"
     protocluster    1..3296
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[90:1320]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      91..1320
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..3296
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3296
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(91..1320)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (77-405). E-value:
                     2.6e-50. Score: 163.4. Matches aSDomain:
                     nrpspksdomains_ctg69_2_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 306.6; E-value:
                     4.8e-93)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_2"
                     /sec_met_domain="APE_KS1 (E-value: 1.7e-171, bitscore:
                     558.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVVITGMGIYSCIGKNQDEVKDSLFQGRSGIGIDPARKEMGYF
                     SALTGLVERPDLKKLLDRKKRHSLAEQGEYAYMATLEAFRQAQIDEEFLLDHEVGILYG
                     NDSSAAPVIEAIDVIRAKKNTAMVGSGSIFQSMNSTITMNLSVIFHLKGINFTISGACA
                     SGSHAIGMAYLLIKSGLQDCILCGGAQEVNPYSVGSFDGLGAFSTREDEPEKASRPFDK
                     GRDGLIPSGGGASLVLESYESAVRRGATILAEVIGYGFSSNGDHISVPNVDGPRRSLQM
                     AINDAGIPLEEIQYINAHATSTPVGDLNEAKAIAEVFGNHRPYVTSTKSQTGHEMWMAG
                     ASEVIYSILMMNNGFIAPNLNFEEPDEASALLNIPSRRIETEFDTFLSNSFGFGGTNSS
                     LIIRKFKENN"
     aSDomain        complement(106..1089)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg69_2_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.60E-50"
                     /label="ctg69_2_PKS_KS.1"
                     /locus_tag="ctg69_2"
                     /protein_end="405"
                     /protein_start="77"
                     /score="163.4"
                     /tool="antismash"
                     /translation="MATLEAFRQAQIDEEFLLDHEVGILYGNDSSAAPVIEAIDVIRAK
                     KNTAMVGSGSIFQSMNSTITMNLSVIFHLKGINFTISGACASGSHAIGMAYLLIKSGLQ
                     DCILCGGAQEVNPYSVGSFDGLGAFSTREDEPEKASRPFDKGRDGLIPSGGGASLVLES
                     YESAVRRGATILAEVIGYGFSSNGDHISVPNVDGPRRSLQMAINDAGIPLEEIQYINAH
                     ATSTPVGDLNEAKAIAEVFGNHRPYVTSTKSQTGHEMWMAGASEVIYSILMMNNGFIAP
                     NLNFEEPDEASALLNIPSRRIETEFDTFLSNSFGFGGTNSSLIIRKF"
     CDS             complement(1328..2056)
                     /NRPS_PKS="Domain: PKS_KR (3-170). E-value: 1e-18. Score:
                     59.7. Matches aSDomain: nrpspksdomains_ctg69_3_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     219.8; E-value: 6.7e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg69_3"
                     /sec_met_domain="adh_short (E-value: 8.3e-38, bitscore:
                     118.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYALVTGGSRGIGRAVCLKLAEMGYHILINYQNNDTEAEATLQQ
                     IREQGSDGELMKFDVTDAVATHAALNGWMEKHPDTYIEVLVNNAGIRRDNLMLWMEQDE
                     WSRVLDISLNGFFNVTQPLLKNMLVKRFGRIINIVSLSGIKGMPGQTNYSAAKGGMIAA
                     TKALAQEVARKHVTVNAVAPGFIRTDMTNGIDENEWKKQIPAGRFGEPGEVAALVGFLA
                     SEQASYITGEVISINGGIYT"
     aSDomain        complement(1547..2047)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg69_3_PKS_KR.1"
                     /evalue="1.00E-18"
                     /label="ctg69_3_PKS_KR.1"
                     /locus_tag="ctg69_3"
                     /protein_end="170"
                     /protein_start="3"
                     /score="59.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAVCLKLAEMGYHILINYQNNDTEAEATLQQIRE
                     QGSDGELMKFDVTDAVATHAALNGWMEKHPDTYIEVLVNNAGIRRDNLMLWMEQDEWSR
                     VLDISLNGFFNVTQPLLKNMLVKRFGRIINIVSLSGIKGMPGQTNYSAAKGGMIAATKA
                     LAQE"
     CDS_motif       complement(1982..2044)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg69_3_0001"
                     /evalue="2.80E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg69_3"
                     /protein_end="25"
                     /protein_start="4"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVCLKLAEMG"
     CDS             complement(2053..3294)
                     /locus_tag="ctg69_4"
                     /transl_table=11
                     /translation="MRLYTFLQGKSGVHKELALLITEFINRGITPYVPEHGSVGASGDL
                     VQLAHIALTLIGEGEVFYQGKKRDTASVLAENGLQPFKMHIREGLSVTNGTSVMTGIGI
                     VNLIYARQLMHWAVGASVMMNEIAASYDDFMSEPLNEAKRHEGQQEIARMMRQWVEGSQ
                     CVRKRENELYNGKHEEKIFTHKVQPYYSLRCIPQILGPVYDELLNAEKVLINEINSACD
                     NPIVDPDTQNVYHGGNFHGDYISFEMDKLKIAVTKLAMLAERQINYLFHDRINGILPPF
                     VNMGVLGLNYGLQASQFTATSTTAECQTLSNPMYVHSIPNNNDNQDIVSMGTNSALLAK
                     TVIENAYQVMAILMMGIVQAVDCLEIAGRLSPRSQQVYKEIRAFFPVFREDTPKYKEIE
                     RMMVYLKKGRLQEK"
ORIGIN
        1 ttctacatca atctcaaatt cttcggccag ggtggttctg atcttttcga tgatttcttc
       61 gttgatcata aatttatata ttggtttgaa ttaattgttt tctttaaatt tacggataat
      121 cagtgaggaa ttggttcctc cgaatccgaa tgagttggac aagaaggtgt caaattccgt
      181 ttctatcctc cgggagggga tgttcagcag agcagaggct tcatcgggtt cttcaaaatt
      241 gagattagga gcgataaatc cgttattcat catcaagatg gaataaatga cttcactggc
      301 gcctgccatc cacatctcat gtccggtttg tgacttggtg gatgtgacat agggccgatg
      361 gtttccgaac acttccgcta tggcttttgc ctcattcaaa tctcccacgg gggtggaagt
      421 ggcgtgtgca ttgatatatt ggatttcttc caagggaatg cccgcatcgt tgattgccat
      481 ctgtaaagag cgtctgggac cgtccacatt cggtacggaa atatgatctc cgttggatga
      541 aaaaccgtat cctatgactt ctgccagaat agtagctccg cgccttacgg ctgattcata
      601 actttcgagt accaggctgg cgcctcctcc gctgggtatc aaaccgtccc gtcccttgtc
      661 aaaggggcgc gatgcctttt ccggttcgtc ctcacgggtg gagaacgcgc ccaatccgtc
      721 gaaactaccc acggagtaag gatttacctc ttgtgctcct ccgcacagaa tgcagtcctg
      781 aagtcctgat ttgataagca gatacgccat gccgatggcg tgtgaaccgc tggcacaagc
      841 tcccgatatg gtaaaattaa ttcccttcaa atggaaaata accgaaaggt tcatggtaat
      901 cgtagagttc atggactgga agatagaacc ggagcccacc atagccgtat tcttcttggc
      961 acgaatgaca tcaatggcct cgattaccgg agcggcgcta ctgtcatttc catacaatat
     1021 gcctacttca tgatccaata aaaactcctc gtctatttgt gcctgacgga atgcctccaa
     1081 ggtagccata taggcatatt ctccctgttc ggcgaggcta tgcctctttt tgcggtccaa
     1141 taacttcttt aaatcaggac gttcgacaag tcctgtcaat gcggaaaaat accccatctc
     1201 tttacgtgcc ggatcgatgc cgatgcctga acgcccttgg aacaaagagt ctttcacctc
     1261 atcttggttc ttgcctatgc acgaataaat acccatgcct gtaatcacta ctcttctcat
     1321 cttctgctta tgtatagatt cctccattga tggaaattac ttctccggtg atataggagg
     1381 cttgttccga tgccaggaag cctaccagtg cggctacttc tccgggttcg ccgaaccgtc
     1441 ctgccggtat ctgttttttc cattcatttt catcaatgcc gttggtcata tccgtgcgga
     1501 taaatcccgg tgctacggcg ttcaccgtca cgtgttttct ggccacttcc tgtgccagtg
     1561 ctttggtggc ggctatcatt ccgcctttgg ctgccgaata gttggtttgt cccggcattc
     1621 ctttgatacc cgacagggaa acgatgttga tgatacgtcc gaatcgcttt accagcatat
     1681 ttttcagcaa gggttgggtg acgttgaaga aaccgttcag gctgatatcc aacacccggc
     1741 tccattcatc ctgttccatc cacagcatca ggttgtcacg gcgtataccg gcattgttca
     1801 ccagtacctc aatgtaggta tcgggatgct tctccatcca gccgttcagt gcggcgtgtg
     1861 tggctactgc gtctgtcacg tcaaatttca tcagttcgcc gtccgagcct tgttcccgta
     1921 tctgttgcag ggtggcttcg gcttccgtat cgttgttttg gtagtttatc agtatatgat
     1981 atcccatttc ggccagtttc agacatacag cccgtccgat gccccggctt cctcctgtta
     2041 ctagtgcgta tttcattttt cttgcaacct ccctttttta agatatacca tcattctttc
     2101 tatctcttta tatttaggcg tatcttcccg gaacacagga aaaaatgctc gtatctcttt
     2161 atatacttgt tgtgaccggg ggcttagccg accggctatt tccaaacagt ctacagcttg
     2221 tacaataccc atcatcagga tagccatcac ctgataagca ttttctatga ctgtttttgc
     2281 cagcagtgcg gaattggttc ccatgcttac aatatcctga ttgtcattgt tgttggggat
     2341 gctatgcaca tacatcggat tggacaaagt ctggcactcc gctgtggtag aagtcgcggt
     2401 aaattgtgac gcctgcaaac catagttcaa tcccagcact cccatattga caaagggggg
     2461 cagaatgccg ttgatgcggt cgtgaaacaa gtaattgatc tgccgttcgg caagcatggc
     2521 cagtttggtg accgctattt tcagtttatc catttcaaaa gaaatgtaat ctccgtgaaa
     2581 attaccgcca tgatacacgt tttgcgtgtc ggggtccact atcgggttgt cacaggctga
     2641 atttatttcg tttatcaata ctttttcggc attgagcaat tcatcataaa ccggtcctag
     2701 aatctgtggg atgcagcgca acgaataata gggttgaacc ttatgggtga agattttctc
     2761 ttcgtgtttt ccgttgtaaa gttcattctc tcttttgcgt acacattggc tgccttccac
     2821 ccattggcgc atcatgcggg ctatctcttg ctgtccttca tgccgtttgg cttcgttcag
     2881 cggttcggac atgaaatcat cgtacgaggc ggcaatttca ttcatcatga ccgatgcgcc
     2941 tactgcccaa tgcatcagtt ggcgggcata aatcaggttg acaatgccta tacctgtcat
     3001 taccgaagtg ccgttggtca ctgaaagccc ttcgcggata tgcattttga agggttgcaa
     3061 tccgttttcc gccaaaacgg atgccgtatc tcttttcttg ccttggtaaa agacctctcc
     3121 ttctccaatc agggtgaggg cgatatgggc aagctgtacc aaatcgccac tggcccctac
     3181 actgccgtgt tcgggtacgt atggagtaat cccccggttg ataaactcgg taatgagcaa
     3241 tgccagttct ttatgtacgc cggattttcc ttgcagaaaa gtatagagac gcgcta
//
