LOCUS       gnlProkkaNIILIAEK_71    3144 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NIILIAEK_71.
ACCESSION   gnlProkkaNIILIAEK_71
VERSION     gnlProkkaNIILIAEK_71
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 01:05:10
            Original ID  :: gnl|Prokka|NIILIAEK_71
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3144
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3144
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1:1168]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..1168
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..3144
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3144
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(2..1168)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (77-372). E-value:
                     2.4e-45. Score: 147.0. Matches aSDomain:
                     nrpspksdomains_ctg71_1_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 282.6; E-value:
                     9.1e-86)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_1"
                     /sec_met_domain="APE_KS1 (E-value: 5e-158, bitscore: 513.7,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGRNQEEVKESLFQGKSGIGIAPARKEMGYF
                     SALTGLVERPDLKKLLDRKKRHSLAEQGEYAYMATLEAFRQARIEEKFLLENEVGILYG
                     NDSSAAPVIQAIDIIREKKNTALVGSGSIFQSMNSTITMNLSVIFHLKGINFTISGACA
                     SGSHAIGMAYLLIKSGLQDCILCGGAQEVNPYSVGSFDGLGAFSAREDEPEKASRPFDK
                     NRDGLVPSGGGASLVLESYESAVKRGATILAEVIGYGFSSNGDHISVPNVDGPRRSLQM
                     AVKDAGIPLEEIAYINAHATSTPVGDLNEAKAIAEVFGSHHPYVTSTKSQTGHEMWMAG
                     ASEVIYSTLMMNNGFIAPNLNFEEPDEASALLNIPSRRVETEFDTFLSN"
     aSDomain        complement(53..937)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg71_1_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.40E-45"
                     /label="ctg71_1_PKS_KS.1"
                     /locus_tag="ctg71_1"
                     /protein_end="372"
                     /protein_start="77"
                     /score="147.0"
                     /tool="antismash"
                     /translation="MATLEAFRQARIEEKFLLENEVGILYGNDSSAAPVIQAIDIIREK
                     KNTALVGSGSIFQSMNSTITMNLSVIFHLKGINFTISGACASGSHAIGMAYLLIKSGLQ
                     DCILCGGAQEVNPYSVGSFDGLGAFSAREDEPEKASRPFDKNRDGLVPSGGGASLVLES
                     YESAVKRGATILAEVIGYGFSSNGDHISVPNVDGPRRSLQMAVKDAGIPLEEIAYINAH
                     ATSTPVGDLNEAKAIAEVFGSHHPYVTSTKSQTGHEMWMAGASEVIYSTLMMNNGFIAP
                     NLNFEEPDEASALL"
     CDS             complement(1176..1904)
                     /NRPS_PKS="Domain: PKS_KR (3-170). E-value: 1.3e-18. Score:
                     59.4. Matches aSDomain: nrpspksdomains_ctg71_2_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     220; E-value: 5.7e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_2"
                     /sec_met_domain="adh_short (E-value: 6.1e-38, bitscore:
                     118.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYALVTGGSRGIGRAICLKLAEMGYHILINYQSNNTEAEATLQQ
                     IREQGSDGELMKFDVTDAAATHAALNGWMEQHPDTYIEVLVNNAGIRRDNLMLWMEQEE
                     WSRVLDISLNGFFNVTQPLLKNMLVKRFGRIINIVSLSGIKGMPGQTNYSAAKGGIIAA
                     TKALAQEVAKKHVTVNAIAPGFIRTDMTDGIDENEWKKHIPAGRFGEPGEVAALVGFLA
                     SGQASYITGEVISINGGLYT"
     aSDomain        complement(1395..1895)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg71_2_PKS_KR.1"
                     /evalue="1.30E-18"
                     /label="ctg71_2_PKS_KR.1"
                     /locus_tag="ctg71_2"
                     /protein_end="170"
                     /protein_start="3"
                     /score="59.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAICLKLAEMGYHILINYQSNNTEAEATLQQIRE
                     QGSDGELMKFDVTDAAATHAALNGWMEQHPDTYIEVLVNNAGIRRDNLMLWMEQEEWSR
                     VLDISLNGFFNVTQPLLKNMLVKRFGRIINIVSLSGIKGMPGQTNYSAAKGGIIAATKA
                     LAQE"
     CDS_motif       complement(1830..1892)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg71_2_0001"
                     /evalue="2.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg71_2"
                     /protein_end="25"
                     /protein_start="4"
                     /score="20.2"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAICLKLAEMG"
     CDS             complement(1901..3142)
                     /locus_tag="ctg71_3"
                     /transl_table=11
                     /translation="MRLYTFLQGKSGVHKELALLITEFINRGIIPYVPEHGSVGASGDL
                     VQLAHIALTLIGEGEVFYQGTKRDTASVLAENGLQPFQMHIREGLSVTNGTSVMTGIGI
                     VNLIYARQLMQWAVGASVMMNEIAASYDDFMSEPLNGAKQHEGQQEIARMMRQWVKGSL
                     CVRKRENELYNGKHEEKIFTHKVQPYYSLRCIPQILGPVYDELLNAEKVLINEINSVCD
                     NPIVDPDTQNVYHGGNFHGDYVSFEMDKLKIAVTKLTMLAERQINYLFHDRINGILPPF
                     VNMGVLGLNYGLQASQFTATSTTAECQTLSNPMYVHSIPNNNDNQDIVSMGTNSALMAK
                     TVIENAYQVMAILMMGIVQAIDCLDIADRISPRSQQVYKEIRAFFPVFREDTPKYKEIE
                     SMMVYLKKGRFQEK"
ORIGIN
        1 agttggacaa gaaggtgtca aattccgttt ctacccttcg ggaagggata ttcagcaggg
       61 cagaggcttc atcgggctcc tcaaaattga ggttgggtgc gatgaagccg ttgttcatca
      121 tcaaagtgga gtaaatgact tcactggctc ctgccatcca catctcatgt ccggtctgtg
      181 atttggtgga tgtgacgtag ggatgatggc tcccgaatac ttccgctatg gcttttgcct
      241 cgttcaaatc acctacagga gtggatgtgg catgtgcatt gatgtatgca atctcttcca
      301 aaggaatacc cgcatccttg actgccatct gcaaagagcg tctggggcca tccacattgg
      361 gtacggaaat gtgatctccg ttggatgaga agccgtatcc tatgacttct gccaggatag
      421 tcgctccgcg ctttacggct gattcataac tttccagcac cagactggcg cctccgccgc
      481 taggtactag tccgtcacgg tttttatcga atggacggga tgctttttcc ggttcgtctt
      541 cccgggcgga gaaggctccc aacccgtcga aactacccac ggaataaggg ttcacttcct
      601 gtgctcctcc gcacagaatg cagtcctgaa gtcctgattt gataagcaga taagccatgc
      661 cgatggcgtg tgaaccactg gcacaggctc ccgatatagt gaagttaatt ccttttagat
      721 ggaaaataac cgaaagattc atggtaatgg tggaattcat ggactggaaa atagaaccgg
      781 aaccaaccaa tgccgtattc tttttctcgc ggataatatc tattgcttga ataaccggag
      841 cagcactact gtcattgcca tacagtattc cgacttcgtt ctccaacagg aacttttctt
      901 ctatccgggc ttgccggaat gcttccaggg tagccatata ggcgtattct ccctgctcgg
      961 caaggctatg gcgtttcttg cggtccaata atttcttcaa atcgggacgt tcgacaagac
     1021 cggttaacgc cgagaaatag cccatttctt tgcgagccgg agcaattccg atgcctgact
     1081 ttccttgaaa cagtgactct ttcacttcct cttgattcct gcctatgcac gaatagatgc
     1141 ccattcctgt aataactact cttttcatct tttgcttacg tatataatcc tccattgatg
     1201 gaaatcactt ctccggtaat gtaggaagct tgcccggatg ccaggaagcc taccagtgcg
     1261 gctacttccc cgggctcgcc gaagcgtcct gccgggatgt gttttttcca ctcgttctca
     1321 tcaattccgt ctgtcatatc tgtacggata aatcccggtg ctatggcatt taccgtcacg
     1381 tgttttttgg caacttcctg cgccaacgct ttggtagcgg ctatgattcc acctttggct
     1441 gccgaataat ttgtttgtcc cggcattcct ttgatccccg acagggagac gatgttgata
     1501 atacgtccga atcgctttac cagcatattc ttcagcaagg gttgggtgac gttaaagaaa
     1561 ccgttcagac tgatatccag tacccggctc cattcttcct gttccatcca cagcatcaag
     1621 ttgtcacggc gtataccggc attgttcacc agtacctcaa tgtaagtatc gggatgctgt
     1681 tccatccatc cgttcagtgc ggcgtgtgtg gctgctgcat ctgtcacgtc aaatttcatc
     1741 agttcgccat ccgagccttg ttcccgtatt tgttgcaggg tggcttcagc ttccgtattg
     1801 ttgctttggt agtttatcag tatatgatat cccatttcgg ccagtttcag acaaatggct
     1861 cgtccgattc cccggcttcc tcctgttact aatgcgtatt tcatttttct tgaaacctcc
     1921 cttttttaag atataccatc atgctttcta tctctttata tttaggtgta tcttcccgga
     1981 aaacagggaa aaatgctcgt atttctttat atacttgttg tgaccggggg cttatccggt
     2041 cggctatatc caggcaatca atggcttgta caatacccat catcaggata gccatcacct
     2101 gataagcatt ttcaatgact gtttttgcca tcaaggcgga attggtaccc atgcttacaa
     2161 tgtcctggtt gtcattgttg ttggggatgc tatgcacata catcggattg gacaaagtct
     2221 gacattctgc cgtggtagag gtggctgtga actgggaggc ctgcaaacca taattcagcc
     2281 ccagcactcc catattgaca aaggggggga gaatgccgtt gatgcggtcg tgaaacaggt
     2341 aattaatctg ccgttcggca agcatcgtca gtttggtgac tgctattttc aacttgtcca
     2401 tttcaaaaga tacataatct ccgtggaagt taccaccatg atatacattc tgtgtgtcag
     2461 ggtccactat cgggttgtca caaactgaat ttatttcgtt tatcaatact ttttcagcat
     2521 tgagtaattc atcataaacc ggccctagaa tttgtggaat gcaacgtagc gaataatagg
     2581 gctgcacttt atgggtgaag atcttctctt cgtgcttccc attataaagt tcattctctc
     2641 ttttgcgtac acacaggctg ccttttaccc attggcgcat catgcgggct atctcttgtt
     2701 gtccttcatg ctgtttggcc ccgttcagcg gttcagacat gaagtcatcg tatgaggcgg
     2761 ctatttcatt catcataaca gatgcaccta ccgcccactg cataagttgg cgtgcgtaaa
     2821 tcagattgac aatacctata cctgtcatga ctgaagtgcc gttggtcact gaaagccctt
     2881 cgcggatgtg catttgaaaa ggttgcaatc cgttttccgc cagcacagag gccgtatctc
     2941 ttttcgtgcc ttggtaaaag acttctcctt ctccaatcag agtgagggcg atatgggcga
     3001 gttgtaccag atcaccactg gcccccacac tgccgtgttc gggtacgtat ggaataatcc
     3061 cccggttgat aaactcggta atgagcaacg ccagttcttt atgtacgccg gattttcctt
     3121 gcagaaaagt atagagacgc gcta
//
