LOCUS       gnlProkkaDAELIKOC_39   22332 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DAELIKOC_39.
ACCESSION   gnlProkkaDAELIKOC_39
VERSION     gnlProkkaDAELIKOC_39
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:58:19
            Original ID  :: gnl|Prokka|DAELIKOC_39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22332
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22332
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2306:17332]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2307..17332
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..22332
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22332
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             214..750
                     /locus_tag="ctg39_1"
                     /transl_table=11
                     /translation="MGIEKEVEIWYAMRATYRREPDAMHLLKKENLGCFIPMQYKICIK
                     KGKKVRALVPVVHNLLFVHARPSDVQRVKSQVTYLQYITDTRSGQKIIVPDGQMQRFIA
                     VSGTYDDHLLYFQPDELNLSKGTKVRITGGEFEGQEGVFLKVKGARDRRVVIEIQGVIA
                     VAMATIHPDLIEVIG"
     CDS             786..1274
                     /locus_tag="ctg39_2"
                     /transl_table=11
                     /translation="MSLSEEAITLQRAAHELMYLGMDGSPVYSDDLSRRNGEVYRLTMA
                     LYRSGVKGTTIEEQANVCLALLMGYSASFVDHGEKQQHVQEVLDCCWDVLDALPASLLK
                     LRLLTACYGEVFDESLADEGRSIIASWDSLSLTPEQQEAVDEFQNVTDNPYPWEYIDE"
     CDS             1288..2310
                     /NRPS_PKS="Domain: NAD_binding_4 (8-133). E-value: 6.5e-14.
                     Score: 43.5. Matches aSDomain:
                     nrpspksdomains_ctg39_3_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 105;
                     E-value: 8.3e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_3"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.1e-97,
                     bitscore: 316.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.3e-15, bitscore:
                     47.3, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4.7e-14, bitscore:
                     43.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNNKSVLITGGTGSFGKKFVETILRDYPQVKKIIIYSRDELKQF
                     ELKQKYPGHKYPQLRFFIGDVRDLERLTRACEGVDVIIHAAAIKQVDTAEYNPEECIKT
                     NVHGAQNVIKAALATGVQHVVALSTDKACAPINLYGATKLTSDKLFTAANNISGSKDIR
                     FSVVRYGNVMGSRGSVIPFFINKRDNGAKELPITDMRMTRFNISLEAGVALVMYAIGHH
                     LGGEIFIPKIPSYHIQDVATAIAPNLPQVEVGIRPGEKLHEEMITVTDALDTIDLGRYY
                     VILPSVSFKHSREEFIRHHNAVPVPDGFHYSSDNNTEWETVETMRENIKKYVDPNFEVK
                     "
     CDS_motif       1303..1350
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg39_3_0001"
                     /evalue="1.80E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg39_3"
                     /protein_end="21"
                     /protein_start="5"
                     /score="11.0"
                     /tool="antismash"
                     /translation="SVLITGGTGSFGKKFV"
     aSDomain        1312..1686
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_3_NAD_binding_4.1"
                     /evalue="6.50E-14"
                     /label="ctg39_3_NAD_binding_4.1"
                     /locus_tag="ctg39_3"
                     /protein_end="133"
                     /protein_start="8"
                     /score="43.5"
                     /tool="antismash"
                     /translation="ITGGTGSFGKKFVETILRDYPQVKKIIIYSRDELKQFELKQKYPG
                     HKYPQLRFFIGDVRDLERLTRACEGVDVIIHAAAIKQVDTAEYNPEECIKTNVHGAQNV
                     IKAALATGVQHVVALSTDKAC"
     CDS             2307..3470
                     /NRPS_PKS="Domain: Aminotran_1_2 (35-167). E-value:
                     1.3e-13. Score: 42.6. Matches aSDomain:
                     nrpspksdomains_ctg39_4_Aminotran_1_2.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     330.2; E-value: 2.8e-100)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_4"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.2e-112,
                     bitscore: 368.1, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.7e-14, bitscore:
                     42.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKPIPYGRQHITDEDIRAVIDTLKSDYLTQGPKIREFETKFAE
                     YVGAQYAVAVNNATSGLHLAATALNVKPGDKVIVTPMTFAASANCIRYCGGEVVFCDID
                     KDTYLMDIRKLEAMLKASPRGTYKGIVPVDFAGYPLDLEEFRKLADEYGLWIIEDACHA
                     PGGYFMDSKGKKQHCGNGCFADCAVFSFHPVKHIATGEGGMVTTNSKELYDKLCLYRTH
                     GITKDPALLHEHHGGWYYEMQELGYNYRLTDFQAALGISQLERAKAGLERRHEIVRRYN
                     EAFSGIDGIKTPFNTADVYHAYHLYIIQVADRLGLYNYLHENNVYAQVHYAPLHLMPYY
                     QQWGNRKGDLPIVEEYYEHCLSLPMYPTLTDEEQEYVIEKVIEFVAK"
     aSDomain        2412..2807
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_4_Aminotran_1_2.1"
                     /evalue="1.30E-13"
                     /label="ctg39_4_Aminotran_1_2.1"
                     /locus_tag="ctg39_4"
                     /protein_end="167"
                     /protein_start="35"
                     /score="42.6"
                     /tool="antismash"
                     /translation="IREFETKFAEYVGAQYAVAVNNATSGLHLAATALNVKPGDKVIVT
                     PMTFAASANCIRYCGGEVVFCDIDKDTYLMDIRKLEAMLKASPRGTYKGIVPVDFAGYP
                     LDLEEFRKLADEYGLWIIEDACHAPGGY"
     CDS             3467..4150
                     /locus_tag="ctg39_5"
                     /transl_table=11
                     /translation="MKNIAIIPARGGSKRIPRKNIKPFMGKPIIAYSIEAALQSGLFEE
                     VMVSTDDEEIAGIACKYGAKVPFMRSAEMSNEYAGTDDVILEVLRKYKEQGREFETVCC
                     IYSTAPFVTPERLREAYGKMNSEIDSVFTCVAYSYPIQRSLHIVDGKISMVYPEYKNAR
                     SQDLEPIYHDAGQFYFSRTAPFVESRTFWGENTAGLVLSELEVQDLDTQTDWALAEMKY
                     ELLHK"
     CDS             4155..5132
                     /locus_tag="ctg39_6"
                     /transl_table=11
                     /translation="MQKIYLRADASAAIGYGHFIRTLALTDMLKDDFDCTFFTCHPTPY
                     QVSEMEKVCPFIPLQEESHYDEFLSLLQGDEIVVLDNYFFTTDYQRAIKQKGCCLVCVD
                     DMHDKHYVADLIVNQGLGYTRDDYSCEPYTQFAFGLQFSLLRRPFFNVALQNKRNNYSG
                     GLYVLVAFGGSDFLNLTYQTIHAIKAKDNVKKITAIVGDSYAAENMVDDPKVTYQKNLS
                     AGSIADLFSTVDVAILPASTMMNEALACGTPVIGGYYVDNQEHDYYMFLREGLIQGAGD
                     YTDAAAFTLVAENLDKMAIRKRHAITPDIPKRFVNLFKSLLICK"
     CDS             5123..5575
                     /locus_tag="ctg39_7"
                     /transl_table=11
                     /translation="MQVTSQRASAILYNYLSGNHFDKPFLLPANVCPVVPLSFMKAGVG
                     FEFIDIDESHAMSTEKCLTAIEAGKYSGLVFVHAYGKKYDNKEFYRAVKSLDPNLCIID
                     DCCLCIPELADSLPENVDLCLYSTGYAKFIELSYGGYASFRGVRSC"
     CDS             5535..6056
                     /locus_tag="ctg39_8"
                     /transl_table=11
                     /translation="MVAMQVLGGYEVVDYQYDSISEQKHSVYIRKCLLENVRYMLPADY
                     PWLDASNLQMTDEEYFDIIERKLPKVIAEKEKINKIYRNLLPESIQMGDDFQNWRFMIV
                     IENRQKVLDAIFKAGLFAGTNFPSVSYMFKGVSSPVAEVEAKHIVNLFNDFRFSEAQAR
                     KICDVINSVI"
     CDS             6053..7192
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 60.5; E-value: 2.7e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_9"
                     /sec_met_domain="ATP-grasp_3 (E-value: 3.7e-15, bitscore:
                     47.7, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 5.1e-12,
                     bitscore: 37.1, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKRLLILGAGEMQVPVIRKANDMGLHTIVADMDANAPGMGYASE
                     PVLVSTMDKEGVLECAKRHSVDGILTTSDAPVNVVSYVGEQLGLPSMSTEVAKICTNKY
                     LQREMFAANGIDVPFFMLCDKDTDLGTLQDYPYIVKPVDSSASRGVKKVTNHKELVLAF
                     SEALGYSRTGKAIVEGFITGREFSVETYTQNNKTTVVTITEKLCIGEAEGFFVEDTHIE
                     PARITKQEWELVSETVSKALCLIGLNNCPSHTEIKLNESGAYIIEIACRLGGDYITSDL
                     VPLSTGIDMLRNLVNCSLGLPVDVLRKHEKCSAVQFLNPLNYQRCVDFLSSSRSSAVFR
                     SEIRPYSEKKIKNSLDRLGYIILQTDSMEELESILRTIK"
     CDS             7200..8216
                     /locus_tag="ctg39_10"
                     /transl_table=11
                     /translation="MRDKCMIVAEMSANHNGKKETAIETVRAAKRAGADAVKLQTYRAD
                     TITLRCDKPDFIINEGSIWDGQYFYDLYEQAYTPWEWHEELFHVAKEEGLICFSSPFDK
                     TAVDMLEALDCPVYKIASFEITDIPLIEYAASKHKPMVLATGIATEEDIQLAVEACRRM
                     GNNDITVLKCTSSYPAPVEEANLCMIRDLAERFQVKSGLSDHTLGSVSPIVAVTQGASM
                     IEKHFILNRSIGGPDCSFSMEEKDFAQMVKDVRMAELSLGKTTYELTEKMRGSRSASRS
                     LYVAEDMKAGEVITERNVRSVRPGFGLHPKYLKDILGKNVNRDLEKGTRFALEYVNG"
     CDS             8561..8734
                     /locus_tag="ctg39_11"
                     /transl_table=11
                     /translation="MAVVIEGMRTYFFQRAAAVYFAVAGQIEMIADVTEAAVVDVVAAA
                     ILKAQGHALRRG"
     CDS             complement(8770..8877)
                     /locus_tag="ctg39_12"
                     /transl_table=11
                     /translation="MSEDKKSKSVWGIVLKVIITVATAIAGALGLGACK"
     CDS             complement(8917..9402)
                     /locus_tag="ctg39_13"
                     /transl_table=11
                     /translation="MIRYKKYQVTGEDSPLKGLWYARPVIEETFDIEKLAKHMSNHNTP
                     YSSGVIKGVLADMVSCTKELILDGKNVKLDDLAIFSVGIVSKKGAQSAADFSLANNVKG
                     LKLRARATGELSNAQINLDGQLKESSLYTVGGKAPDGSGSDGGSGGSDGNQGENPLG"
     CDS             9951..10217
                     /locus_tag="ctg39_14"
                     /transl_table=11
                     /translation="MSDFWFPVVSLAIYIFYQPVFLHAFEPGGGGFRFDAHLSGFLQER
                     GPCEFFFHAVYQRIPVGIAAACHFGVGQEGEDMGGMPVKAFGQ"
     CDS             10503..10703
                     /locus_tag="ctg39_15"
                     /transl_table=11
                     /translation="MKGEYSVHDNGFQFVLPFHAQRLEGIFKIAVIAVELVLPMMYGRH
                     VVEYLAGKEPVLSSGNQWFHL"
     CDS             10758..11135
                     /locus_tag="ctg39_16"
                     /transl_table=11
                     /translation="MVGAAVVGQSVVVEGFAHGVAPVSVFRTDGGGDGVGFAFAYQSGT
                     VGVHQVLQDAGSGVVARDEEHLVERHYGSLRFSTFLAQCVVFCFFAAVTCHTFVYLLTY
                     FIVNGLGKQAYQGEHSFAGCR"
     CDS             11445..11588
                     /locus_tag="ctg39_17"
                     /transl_table=11
                     /translation="MLNLHAAKLGQMKGGSQMHVVTASLQGIAEELVGCPLVVLGRQAA
                     QT"
     CDS             complement(11781..12413)
                     /locus_tag="ctg39_18"
                     /transl_table=11
                     /translation="MPKSFKMSLFMPPISPMKDGATGKIVKSATLTPLRTLELNEVYQL
                     ITANKRLITLTQAIREAALQGDDNNCRMLKQQTLPYVTPCGVFTRRRSDCLKLPSGLMV
                     VDVDHLDSPDEAGRLKQLLFKDPYLAPVLVFISPTGRGVKAFVPCPIGKDSTEAVRWAM
                     NYVHCMYDAENTQPGKGVDTSGKDLVRACFLCHDPKALLRKVVNFEL"
     CDS             12558..12698
                     /locus_tag="ctg39_19"
                     /transl_table=11
                     /translation="MGKNFIHPSLGFFIERTRKQSGVTIETLCKDLHISPSTYIDLKKR
                     V"
     CDS             12882..12983
                     /locus_tag="ctg39_20"
                     /transl_table=11
                     /translation="MINFTVGLVQSSDAVQAIGAEQVPYLEQQSSQK"
     CDS             12980..13732
                     /NRPS_PKS="Domain: Aminotran_5 (3-213). E-value: 9.4e-22.
                     Score: 69.2. Matches aSDomain:
                     nrpspksdomains_ctg39_21_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_21"
                     /sec_met_domain="Aminotran_5 (E-value: 6.1e-19, bitscore:
                     59.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMLENERLVKKFANATKDSKVVFMTCSGSGGMEAAIINCLTPQDK
                     ALVINGGSFGERFVELLTLHKIPFTEIKLKYGRALKPEHLAEYESKGYTTFLMQKHETS
                     TGVHYDINLVSDFCKRNNCFLIVDTISTFLCDSFDMVAMDVGVMITGSQKALACAPGIA
                     VMILAPSAIKRIEKVQCCCQYLDLKLALKNMERGQTPCTPAVGILRQINVCLKEIESAG
                     GAEVEIARCAELAKYFRDKLVKNNLPLF"
     aSDomain        12989..13618
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_21_Aminotran_5.1"
                     /evalue="9.40E-22"
                     /label="ctg39_21_Aminotran_5.1"
                     /locus_tag="ctg39_21"
                     /protein_end="213"
                     /protein_start="3"
                     /score="69.2"
                     /tool="antismash"
                     /translation="ENERLVKKFANATKDSKVVFMTCSGSGGMEAAIINCLTPQDKALV
                     INGGSFGERFVELLTLHKIPFTEIKLKYGRALKPEHLAEYESKGYTTFLMQKHETSTGV
                     HYDINLVSDFCKRNNCFLIVDTISTFLCDSFDMVAMDVGVMITGSQKALACAPGIAVMI
                     LAPSAIKRIEKVQCCCQYLDLKLALKNMERGQTPCTPAVGILRQINV"
     CDS             13729..14103
                     /locus_tag="ctg39_22"
                     /transl_table=11
                     /translation="MTYRQVGTNSFTVKYYVEKFILDMNTMKIIRVDEYRDKKKINRPA
                     GSLFSVDGEIYRVAQKCSRAYGESIFVYKTSKNFDFIKDKKVAELTGQSIVLSDGRKPI
                     LLHTYSQAGGIEVIDYRCSL"
     CDS             14128..15438
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 190.9;
                     E-value: 4.6e-58)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_23"
                     /sec_met_domain="CTP_transf_like (E-value: 4.2e-12,
                     bitscore: 37.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 4.8e-114, bitscore:
                     371.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3e-61, bitscore:
                     198.3, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTVYLGMIGDIMHPGYINIINKATEYGDVIIGLFTDKAIANHR
                     RLPYLTWEQRKNVVESIRNVSRVVPQDDWSYVSNLLKYKPDYIIHGDDWQVGPDKYIRD
                     EVFKVMEKLGGEVIEIPYTQNISASGIKQEIDALGVTPQMRLSSLRRLIAAKPIVRILE
                     SHNGLTGLIAEHTKVEVNGQEREFDGMWASSLTDSTSKGKPDIEAVDLTTRLHDLNDTL
                     EVTTKPVIFDGDTGGKIEHFGFTVRTLERLGISCVIIEDKVGLKQNSLFGTDAVQTQDT
                     IEGFQAKIRAGKEAQITRDFMIVSRCESLIAGKTVDDALERCHAYVEAGTDGIMIHSKE
                     KSGEDIKEFCLRFREKNAHTPIIVVPTTYNQFTEEELAEWGINVVIYANHMLRSAYPAM
                     VKCAETILYTSRSLEASEQYCMPIKQILNLIPGTKKK"
     CDS             15473..16600
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 74.7;
                     E-value: 1.1e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_24"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.4e-20, bitscore:
                     63.8, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-23, bitscore:
                     74.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRPEFFVNILKEQGIDFYAGVPDSLLKNICAYITDHLPAEQNII
                     AANEGGAMGIAVGYHLATGKVPVVYMQNSGEGNIINPFASLTDKDVYNIPVLLVIGWRG
                     RPGVHDEPQHVKQGKVTIGLLNTMGINYAILPKDEEGAAKQIKIAVDFMKATNECYALV
                     IEKDTFDTYKLQSVEVNELAMSREETIQKVASNIEDNACIVSTTGMISRELFEARTAWS
                     QGHERDFLTVGAMGHASQIALGIALQKPERRVYCFDGDGASIMHMGNMAITASMKCKNY
                     VHIVFNNGAHDSVGGQPTVGLKIDFCAIAQAVGYKAAYSVETMEALEAKLAEFKNAEGP
                     VFLQICVKKGNRKDLGRPTTTPIQNKEAFMEFLNK"
     CDS             16604..17332
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Metallophos_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_25"
                     /sec_met_domain="Metallophos_2 (E-value: 1.6e-27, bitscore:
                     88.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVILFADIHANLSAFEAVLADIEKHYQPDAMISLGDFIDYGMRS
                     NEIIERIQTVNIPLLANLKGNHEKALIDGELSCFSSERARVMSKYTRNHLTQTSIDYIS
                     NVMQEPMQELEIGGKKVLLLHGTIDDPYWGKLTPAKVEDEKYQDFDYVLSGHIHQPFKI
                     DVFFKVDNPIMRNQKRTTFINPGSVGQPRNQNPYAQYVYINFKTGETHFNAVPYDIEAE
                     QSLFPKEIDTFYSERLKFGI"
     CDS             17333..18328
                     /NRPS_PKS="Domain: NAD_binding_4 (83-198). E-value:
                     6.4e-10. Score: 30.4. Matches aSDomain:
                     nrpspksdomains_ctg39_26_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     142.3; E-value: 3.7e-43)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_26"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.1e-09,
                     bitscore: 27.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.6e-08, bitscore:
                     25.3, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLYVISGVTGMTGSELSRQFVSQGHTVIGFDNFFASSIDTVKD
                     IIDNPSFIFYNYDINKVAQMDEVCDKAKELKIECDGRLVFINCAAVVHTKHFYEVESTF
                     QTNVLAMKDFLERAISMRADTYINCSTSEVYSMQSWNENGGVKESDYLAMSTAEHSQRT
                     SYACGKLMTEFFMKDAVGKGRIKGCSIRFANVYSRHERFAEHIIPHIIDNLLESHTVTL
                     LENSKVNKRTFLHNIDSCRAVMELIASEDALDGTVYNVATEEEIAIIDLVKTIAIKMGI
                     NDVDIRFEGYRKSDPERRLLNTDKIRTRTSWKPIITLDEGLTMCVSGIKK"
     aSDomain        17582..17926
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_26_NAD_binding_4.1"
                     /evalue="6.40E-10"
                     /label="ctg39_26_NAD_binding_4.1"
                     /locus_tag="ctg39_26"
                     /protein_end="198"
                     /protein_start="83"
                     /score="30.4"
                     /tool="antismash"
                     /translation="VFINCAAVVHTKHFYEVESTFQTNVLAMKDFLERAISMRADTYIN
                     CSTSEVYSMQSWNENGGVKESDYLAMSTAEHSQRTSYACGKLMTEFFMKDAVGKGRIKG
                     CSIRFANVYSR"
     CDS             18325..19065
                     /locus_tag="ctg39_27"
                     /transl_table=11
                     /translation="MKYLIITVAGTATRFNRDTKEETLKCLYYTDEPQYALLAQLLKNC
                     GEYDKYILVGGYLYEKLGRFVKNELSGYGKKIELVYNEHFKDYGSGYSLYKGIEAIKEA
                     GDVTFVEGDLFFMATDFRQVYNSPKSVITINREPIYSNKAVALYINVDGKPRYLYDTNH
                     QTLTVSEPFKAIFNSGQMWKFSSSERLLKTVDSLTKEQLQGTNLEIIQAYFSDMNSEEY
                     DVVTFTDWFNCNTVADYDIVRKLM"
     CDS             19074..19487
                     /locus_tag="ctg39_28"
                     /transl_table=11
                     /translation="MAVLERDYRIDGIKWLLIVLVTFGHVIEPALSNPIANKLYSIIYI
                     FHMPLFVFISGYYANVKNKEKLISKGFMLLETFLVVMIPQCFYYGSIIPLLNPENSGWY
                     LISLITWYIIFLLIINKLVGKIVVQYNGCGGSY"
     CDS             19520..20080
                     /locus_tag="ctg39_29"
                     /transl_table=11
                     /translation="MLPLKQFGNLLSFQRSCMFLPFFMMGFLRRVKGLPIIPDVSKCIK
                     LVLAIASLVCFAFCLIYSGRILHVLEFNNANVWHMSNLYNQNIGMLLVLKVLVYIGSII
                     TTFAVLMFVNLPKSICAYGSKTLAYYVIQGMFAHILSTYLQVNFYQALFLCVCILVLTT
                     VLLRFVDSKFITNPFSTLLKWKY"
     CDS             20068..21255
                     /locus_tag="ctg39_30"
                     /transl_table=11
                     /translation="MEILNRKLSLLKGKVENSQPITIMIIGLGSVGCYLLDYLVSLGDS
                     QLRLVVVGRNAEKMQMDINIIRTASTIRHQCRSEIKVVDNCDLNDVNSIAAVLEAEKPD
                     FIVNSSRVYSGLKYGSISWSNLRAYGIWTPLSIRYAKNIMEAYDKANCEAISINTSYSD
                     AVIPWLKSAGKAYFDFGSGNLNHLVPRIKFYIAEKYGIKNFNDIDVTIAVSHFHDVVIS
                     KEGHAEGQDILLDIKFQGKDMDFNKEELLKSCSIAMPVDQKRNMMNASSNFDIIFSVLT
                     ALREEKQVKIHTPGVNGEIGGYPIIIDGVTATAKFDESVWTIDQMRKANRESIYCDGVE
                     NITDATLVYTDELVAKVKKSFNVDLPKSVKFVDIENVADLIINQIIKPQVFIFVQ"
     CDS             21580..21840
                     /locus_tag="ctg39_31"
                     /transl_table=11
                     /translation="MKNVINMDITTKIKRSKLLYYVYYYVMSGLVNLYKLFLKPDGKLM
                     LFVCYGGRHYSDSTRVIYEAMLKDERFKDYIGLRQTDCCIY"
ORIGIN
        1 aaacgaacgt ctattgaacg ctttttgctt gcaatagatt cgtttacagc attttacctg
       61 acaggtaatg aatgactgca aaaaatctgt tgacaagaag ggcataaagc ttgtcgtatt
      121 ctacataaag tgtccgcaag taattgaatt tcaagtgtat acaagaggtt caaagcccca
      181 ggagaacacc cttgtctgaa caaaagcata aaaatgggaa tagagaaaga ggtcgaaatc
      241 tggtatgcta tgcgtgccac ctaccgcaga gaaccagatg ccatgcatct gctcaagaaa
      301 gaaaatttgg gctgtttcat tcctatgcaa tacaagatat gtataaaaaa agggaaaaaa
      361 gtccgtgctc tggttccggt cgttcataat ctgctttttg tccatgcccg tccttccgat
      421 gtgcagcgtg taaaatctca agtcacttat ctgcaatata tcaccgatac ccgcagtggg
      481 cagaagatta ttgtcccaga cggtcagatg cagcgtttca ttgccgtatc cggcacttac
      541 gatgatcatc ttctttattt tcaaccggat gaattgaact tgtccaaagg caccaaagtc
      601 cggattaccg gcggtgaatt tgaggggcaa gagggtgtgt ttctgaaggt gaaaggcgca
      661 cgtgaccgtc gcgtggttat cgaaatacaa ggtgtcatag ctgttgccat ggccactatc
      721 catcccgatc ttatagaagt aatcggctga actttaattt ttaattctta attctataat
      781 tgcttatgtc tctttccgaa gaagcaatca ctcttcagcg tgctgcgcac gaactgatgt
      841 atttgggtat ggacggcagt cccgtctata gcgatgactt gtcacggcgg aacggtgagg
      901 tctaccgtct taccatggct ttataccggt cgggtgtaaa aggcactacc atcgaagagc
      961 aggcaaatgt ctgtcttgcc cttcttatgg gttacagcgc ctcttttgtg gaccatggcg
     1021 aaaagcagca gcatgtccag gaagtgctgg actgttgttg ggatgtgctc gacgcccttc
     1081 ccgcttcctt actgaagctc cgtctgctta ccgcctgcta cggtgaagtg ttcgacgagt
     1141 ctttggccga cgaaggccgt tccatcatcg cctcctggga ttccttatca cttactcccg
     1201 aacagcagga agcggttgat gaatttcaga atgtgacaga caatccctat ccatgggaat
     1261 atatcgatga ataaaacttt tcatataatg cttaacaata aatccgtatt gattaccgga
     1321 ggaacgggtt ccttcggaaa gaagtttgtg gaaaccattc tccgtgatta tccgcaagta
     1381 aagaaaatta ttatttactc ccgcgatgag ctgaagcaat ttgagctgaa acagaaatat
     1441 cccggtcata agtatccgca actacgtttc tttatcggtg atgtccgtga cctcgaacgc
     1501 ctgacgcggg cttgcgaagg agtggacgtg attatccatg cagccgccat caagcaggtg
     1561 gataccgctg aatacaatcc cgaagagtgc atcaaaacca atgtacacgg tgcgcagaat
     1621 gtgataaagg ctgctcttgc caccggtgta cagcatgtgg tggccctttc tactgacaag
     1681 gcttgtgccc ccattaatct ttatggcgcc accaagctca cttccgacaa gctgtttact
     1741 gccgccaaca atatcagcgg ttccaaggac atcaggttct ccgtagtccg ttatggcaat
     1801 gtgatgggtt cccgcggttc cgtaatccct ttctttatca acaagcgtga caacggggcg
     1861 aaggaacttc ccataaccga tatgcgcatg acccgtttca acatttcact ggaagccggt
     1921 gtcgctttgg tcatgtatgc catcggacat cacctgggtg gtgaaatctt tattcctaag
     1981 attccttcct atcatatcca ggacgtggct accgccattg cacccaatct gccgcaggtg
     2041 gaagtgggca tccgtccggg agagaaactg cacgaggaga tgattactgt aaccgatgct
     2101 cttgatacaa tcgatttggg cagatattat gtcattcttc cttccgtatc tttcaagcac
     2161 agtcgcgaag agttcatcag acatcacaat gcagtacccg ttcccgacgg tttccactac
     2221 agcagtgaca acaatacgga gtgggagaca gtagagacta tgcgcgagaa tatcaagaaa
     2281 tacgttgacc ctaatttcga ggtgaaatga taagcaagcc tattccatac ggtcgtcagc
     2341 atatcacaga tgaggacatc cgggcagtca tcgataccct gaaaagcgat tacctgacac
     2401 aaggtcccaa aatcagggaa tttgaaacga aatttgccga atatgtaggt gcacaatatg
     2461 ccgtagcggt gaacaatgct acttcggggc ttcatcttgc agctaccgca ctgaatgtaa
     2521 agccgggtga caaggtgatt gtcactccca tgacctttgc tgccagtgcc aactgcattc
     2581 gctattgtgg cggcgaggtg gtattctgtg atattgacaa ggatacttac ctcatggata
     2641 tccgtaaact cgaagccatg cttaaagctt ctcctcgcgg tacttacaaa ggtattgttc
     2701 cggttgattt tgcaggctat cctttggatc tggaagagtt cagaaagctt gccgacgagt
     2761 acggtttgtg gattatcgag gatgcctgcc atgctcccgg cggctatttc atggacagta
     2821 aaggcaagaa acaacattgt ggtaacggtt gttttgccga ctgtgccgta ttctctttcc
     2881 atcccgtgaa acatatcgct acgggtgagg gaggcatggt gaccaccaac agcaaggagc
     2941 tctatgacaa gctttgtctt taccgtacgc atggcattac gaaagaccct gccttattgc
     3001 acgagcatca tggtggctgg tattacgaga tgcaggagtt agggtataat taccgtctga
     3061 ctgattttca ggctgccttg ggtatttctc agctggagcg tgcgaaagca ggtcttgaac
     3121 gtcgtcatga aatcgtaaga cgctataatg aagcgttttc cggaatagat ggtatcaaga
     3181 ctccgttcaa tactgccgat gtctatcatg cttatcacct ttatatcatt caagtagctg
     3241 accgcttggg tctttataat tatctgcacg agaacaatgt ctatgcgcag gttcattatg
     3301 ctccgcttca tctgatgcct tactatcagc agtggggcaa taggaaaggc gatttaccta
     3361 tagtagaaga gtattacgaa cattgtctga gtcttccgat gtatcccacg ctgacggacg
     3421 aggaacagga gtatgtgatt gaaaaggtta tagaatttgt agcgaaatga aaaatatagc
     3481 aatcattcct gcacgtggcg gcagtaaacg tattccgcgt aagaatatca agccctttat
     3541 gggtaaacct atcattgcat attccataga ggcagcttta caaagcggtc tttttgagga
     3601 ggtgatggtt tctaccgatg atgaggagat tgccggaata gcttgtaagt atggtgccaa
     3661 agttcctttt atgcggagtg ccgagatgtc aaatgaatat gccggtactg atgatgtaat
     3721 tcttgaagta ctgaggaagt ataaagagca aggcagggag tttgaaacgg tttgttgcat
     3781 ttactcaacg gctccttttg tcactcccga aagactccgg gaagcatacg gaaaaatgaa
     3841 ttcggagata gattccgttt tcacttgtgt ggcttattcc tatcctatac agcgcagcct
     3901 tcacatcgtg gatggaaaaa ttagtatggt ttatcccgaa tacaaaaatg cacgttccca
     3961 agatttagaa ccgatttatc acgatgccgg tcagttctat ttctctcgca ctgctccctt
     4021 tgtggagagc cggacttttt ggggtgagaa tacagccggg ttggtacttt ccgaacttga
     4081 agtgcaggac cttgatacac agactgactg ggcattggca gagatgaagt atgagttgct
     4141 tcataaatga tgtaatgcag aaaatctatc tccgtgccga tgcaagtgct gccatcggct
     4201 acggtcactt tattcgtact ctggctttga ccgatatgct gaaggacgat tttgattgta
     4261 ccttctttac ttgccatcct accccttatc aggtgagtga gatggagaag gtatgtcctt
     4321 tcatcccctt acaggaagaa tcacattatg atgagttcct ttcccttttg caaggtgacg
     4381 aaattgtggt acttgacaac tatttcttta ctactgatta ccagcgtgcc atcaagcaaa
     4441 aaggttgctg tctggtgtgt gtggatgata tgcacgacaa gcactatgtg gctgatctta
     4501 tagtcaatca gggattgggt tacacgcgtg atgactattc gtgtgaacca tatactcaat
     4561 ttgcctttgg gcttcaattt tcattgttga ggaggccttt cttcaatgtt gcgctgcaga
     4621 ataaacggaa caattattca ggaggtttat atgtattggt ggcttttggt ggttctgatt
     4681 tcttgaattt gacgtatcag accattcatg caattaaagc caaagacaat gtgaagaaga
     4741 taacggcaat tgtcggtgat tcgtatgcag ccgagaatat ggttgatgac cccaaagtaa
     4801 cctatcagaa gaatttgtct gccggttcca ttgcagactt gtttagtact gtagatgtcg
     4861 ccatattgcc tgcctctacg atgatgaatg aggcattggc ctgtggaact cctgttatag
     4921 gagggtatta tgttgataat caggagcacg actattatat gtttttgcgt gaagggctga
     4981 ttcagggggc gggtgattat accgatgccg ctgcctttac tcttgttgct gagaatttgg
     5041 ataagatggc cattcgtaaa agacatgcca tcactccgga tattcccaaa cggtttgtca
     5101 atttgtttaa aagtctgttg atatgcaagt aacttcacaa agagcttcgg ccatattgta
     5161 taattatctg tctggcaacc attttgataa accgttctta ttgccggcaa atgtgtgtcc
     5221 tgtagtgccc ctgtcgttta tgaaagcagg tgtcggtttt gagtttatag acatagatga
     5281 aagccatgcc atgtcaaccg agaaatgttt gacagctata gaggcgggaa aatattccgg
     5341 tcttgtattt gtgcatgcct acgggaaaaa gtatgacaac aaagaatttt accgggcagt
     5401 gaaaagtctc gatccaaatc tttgtatcat tgatgattgt tgcttgtgca ttcccgaatt
     5461 ggcagattcc ttgcctgaaa atgtggatct ctgcctttac agtaccggat atgccaaatt
     5521 catagaactt tcctatggtg gctatgcaag ttttaggggg gtacgaagtt gttgattatc
     5581 agtatgatag cattagtgaa caaaagcatt cggtatatat aaggaaatgt ctcctggaga
     5641 atgtcagata tatgcttccg gctgactatc cttggctgga cgcctcaaat ttacaaatga
     5701 ccgatgagga atattttgac atcattgaaa gaaagctccc aaaagtgatt gcggaaaaag
     5761 agaaaataaa caagatatac aggaatctgc ttcctgaatc gattcagatg ggagatgatt
     5821 tccagaactg gaggttcatg attgtcatcg agaaccggca gaaggttctt gacgcaatat
     5881 tcaaggccgg tctgtttgcc gggactaatt tcccttcggt ttcatacatg ttcaaaggtg
     5941 tttcttctcc tgttgcggaa gtggaggcga agcatatcgt caatttgttt aatgatttcc
     6001 ggttcagtga agcacaggca agaaagatct gtgatgtgat aaattcggtt atatgaataa
     6061 aagattattg atactgggcg caggtgaaat gcaggttcct gtcatccgaa aggcgaacga
     6121 tatgggattg cataccatag tcgcagatat ggatgcgaat gctccgggaa tggggtacgc
     6181 ctcggaaccg gttcttgtca gcacgatgga taaggaaggt gttttggaat gtgccaaacg
     6241 tcactctgtt gacggcatac ttactacaag tgacgcgcct gtaaatgtgg tttcctatgt
     6301 cggggaacag ctggggcttc cgtccatgtc cactgaggtc gcaaaaatct gtacaaacaa
     6361 atacttgcag agggaaatgt ttgcggccaa cgggattgat gtaccatttt tcatgctttg
     6421 tgataaagat acggacttgg gcacattgca agattatcca tatattgtca aaccggtaga
     6481 ttcctctgca agccgcggag taaaaaaggt tacaaatcat aaagaacttg tacttgcttt
     6541 ttccgaagct ctcggttatt cccgtaccgg aaaggccatt gtcgagggct ttataacagg
     6601 ccgtgaattc agtgttgaaa catatacgca aaacaataaa actaccgttg tcactattac
     6661 ggagaaactt tgtatcggtg aggcagaagg cttctttgtt gaagatacgc acattgaacc
     6721 ggcgcgtata acgaaacagg agtgggagct ggtttcggag accgtatcaa aagcactttg
     6781 cctgattgga cttaataatt gcccctcgca tacagaaata aagctgaatg aatcgggcgc
     6841 ttatatcata gaaattgctt gtcggcttgg aggagattat ataacctctg atttggttcc
     6901 attgtcaacc gggatagata tgctgagaaa tctggtgaac tgttctcttg gtttgcccgt
     6961 tgatgtcctt cgcaaacatg aaaaatgctc agcggtacag ttccttaatc cgctcaacta
     7021 tcagcgttgt gtggattttc taagctcttc ccggtcatcg gctgtttttc ggtctgaaat
     7081 aagaccttat tctgaaaaaa aaataaaaaa ctctttagac cgtttagggt atatcatact
     7141 tcagactgat agtatggaag agcttgaaag tattctaagg acgattaaat agtaaagaca
     7201 tgagagataa gtgtatgatt gtggctgaga tgtctgccaa ccataacggt aagaaagaaa
     7261 cagccattga aaccgtcagg gctgcaaaac gtgccggagc cgatgccgtc aagttgcaga
     7321 cctatcgggc tgataccatt acgcttcgct gtgacaagcc tgattttata attaatgaag
     7381 gctctatatg ggacgggcaa tatttttatg atttgtatga acaggcttat actccttggg
     7441 agtggcatga agagttgttc catgtggcca aggaagaagg actgatctgt ttttcttctc
     7501 cttttgataa gacagccgtc gatatgcttg aggctttgga ctgtcccgtt tataagatag
     7561 cttctttcga aattacggat attccattga tagaatacgc ggcttcgaag cataagccga
     7621 tggtacttgc tacaggcata gccaccgaag aagatattca attggctgtt gaagcttgcc
     7681 gcagaatggg aaataatgat attacggttc ttaagtgtac ctcttcttat ccggctccag
     7741 ttgaggaagc caatctttgt atgattcgtg atttggcaga acgtttccag gtaaaaagtg
     7801 gactttccga ccataccctg gggagtgtct ctcccattgt ggcggttact caaggtgcga
     7861 gtatgataga aaagcacttt attttgaatc gttccatcgg tggtccggat tgttcttttt
     7921 ctatggaaga gaaagatttt gcccaaatgg taaaagatgt gcgcatggct gagttatctt
     7981 tggggaaaac gacttacgaa ttgacggaga aaatgagagg tagccgttcc gcatcacgtt
     8041 ctctctatgt ggccgaggat atgaaggccg gagaagtgat tacggagcgg aacgttcgct
     8101 ccgtccgtcc gggcttcggc ctgcacccca aatatctgaa agatatattg ggaaagaacg
     8161 tgaaccggga tttggagaaa gggacgaggt ttgcattgga gtacgtgaat ggttagcttg
     8221 ataaaaataa gaagataaaa tagaggtctg gaatttattt ttctatcttt gttcgtaggt
     8281 aatggatatg gaaaagttga ttactttagg ttctgaaata taaagactca aataaaggat
     8341 tatagggagc cttttacagc cccctatact ccttttccgc atcgaagcac ggacacgctt
     8401 tcgtcggatt caagtcatgg tgccccacaa tcagcgcccg tggaaagata cgcttcaact
     8461 cacgtagcag tgccagtaac gaagccttct gttccaatgt acgggtatcg gcaggaaaac
     8521 ttgcagcatc cagtcctcct tcataacaga tgccgataga atggcggttg tgattgaggg
     8581 aatgcgcacc tattttttcc aacgggcggc cgcggtgtat ttcgccgttg cgggtcagat
     8641 agaaatgata gccgatgtca cggaagccgc ggtggtggat gtggtcgcgg cggcaatcct
     8701 caaagcccag ggccacgcct tgaggcgtgg ctgagcaatg aacaatgagc agggtaatcg
     8761 tacgcatggc tatttgcaag cgcccagacc taaagctccc gctatggcgg tagctacggt
     8821 gatgattact ttgaggacaa tgccccatac ggattttgac tttttgtctt cactcatgat
     8881 gactggtaat tgataattag taatttgtaa ttattctcat cctaacggat tctcgccctg
     8941 attgccgtca cttcctccgg aaccgccgtc ggaaccactg ccatcgggag cttttccgcc
     9001 tacggtgtac agggaagatt ccttcagctg tccatccagg ttgatttggg cattactcag
     9061 ttcgccggtg gcacgggcgc ggagcttcag ccccttcacg ttgttggcca gcgagaagtc
     9121 ggcagcggat tgcgcccctt tcttgctgac gattcctacg gagaagatgg caaggtcatc
     9181 cagtttcacg ttcttgccgt ccagaatcaa ttctttagtg caggaaacca tgtctgccag
     9241 tactcccttg atgacaccac tcgaataggg ggtgttgtga ttggacatgt gcttggccag
     9301 tttttcgatg tcgaaggttt cttcgattac ggggcgtgca taccagaggc ctttcagtgg
     9361 gctgtcttcg cccgtcactt gatacttttt gtaacgaatc atacaattaa aatttagaag
     9421 ttaaaggata aaaacatttg ctgtgttgaa ctcaacgatg caaagataag gctgtggata
     9481 cgggcgtttg tcggtttttg caggttctcg tctgtttggg tctgttttag tcggttattt
     9541 acgcttgtaa gtttgataat gtcatgattt atagttactt ttgatgaaat ataaatcgta
     9601 actgtcaact atggattctt ttgtcatacg tacatacggg cgtaccgaat tggcccaaat
     9661 ctattgtccc aatctttgtc cggaggctgc cttccgcaaa ctgaaacact ggatagacct
     9721 ttgtcccgat ttgcgtgacg gactttccgc tttgggcggt tcttcccgtt cccgctctta
     9781 tacgcctgcc caagtgcggc tgatagtggc tgcacttgga gagccttaaa cctgaggttg
     9841 gatggcgtaa aggtcaggcc gggaatcgta aaggtgaggt tggtacactt ggtacagagg
     9901 ttcatccatc ctttcgcctc acacacatac gcgtgcgtga agcgaagtga atgtcagact
     9961 tttggtttcc ggtagtttcc cttgccatct acattttcta ccagcccgtg tttctgcatg
    10021 cgtttgagcc aggtggaggc ggtttccgat ttgatgccca tctctccggc tttctgcagg
    10081 aaagaggccc gtgtgaattc ttcttccatg ctgtctacca gcgcatcccg gtcggcattg
    10141 ccgcggcttg tcacttcggt gttgggcagg aaggagagga tatgggtggt atgccggtaa
    10201 aggctttcgg ccagtgagag tacggcatga aagtcatcgg aagcaatgag gagatcccat
    10261 cggctgacaa tgtggtcttt cagattgtct gtggctgtgt gagggtcggg cgacacgtaa
    10321 ggcgaggcgg tgatttcccc ttgttccatt gcgcggagca tggccactac ttccatgatg
    10381 cggcagatgt tgatggccag acgtgccacg ctgcttgaca tctcgtttcc gttggccagt
    10441 ccggagcgta cgaaaagccg ggagaagagt cggttgaatt catctttctg tccgtccgta
    10501 aggtgaaggg tgaatattcc gttcatgaca atggttttca gtttgtcctt ccattccatg
    10561 cccagcgcct tgaaggtatc ttcaagatcg ctgtcattgc ggtcgaactg gttttgccaa
    10621 tgatgtatgg caggcatgta gtagaatact tggcgggaaa agagcccgtt ctcagcagtg
    10681 ggaatcagtg gtttcacttg tgagggggtg cctgacagaa gtacggaaag ataagttttc
    10741 tttacctctc ggtattcgtg gtcggtgcgg cggttgtagg acagtcggtc gtggtcgaag
    10801 gctttgcgca tggtgtcgct ccagtgtccg tattccgaac cgatggcggt ggagatggtg
    10861 tcggcttcgc tttcgcatat cagtccggta ccgtcggagt ccatcaggtt ttgcaggatg
    10921 ccggttccgg tgttgttgcc cgagatgagg aacatcttgt tgagaggcat tacgggagtc
    10981 tccgtttttc cacgttcctt gcccagtgtg tcgtattttg ctttttcgcg gcggtaacat
    11041 gccatacttt cgtctacctg ctcacgtatt tcatcgtgaa tgggctcggc aagcaggcgt
    11101 accaaggaga gcactccttt gccggatgca ggtagggcta ctacaaaggt ttgcaggcag
    11161 ggggacatca tttttcctcc gtaggaacat cggacgtgtt ttcccatact ggcacccaat
    11221 acggtgatgg cacccagtag cagtacatcg tattgggcga gggaggttcc gcagctcatg
    11281 atgcgattca ggggataagg ccagtggagg tgttcgtcga aagtgggtaa tggagacagt
    11341 ggttcaatgc ccgatgtgga ctcttcctcg cgtgcgcgtg tgtgtgaggt agaagagagg
    11401 ggtgaacttt gtgtaccaag tgtaccaatg gcgggtgcgg cttcatgctg aatcttcacg
    11461 ccgcaaagct cggccagatg aaaggcggtt cccagatgca cgtcgttacg gccagtcttc
    11521 agggcattgc tgaagagctt gtcggctgcc cgttggtcgt acttggacga caggctgcac
    11581 agacttaaaa aatcatgccg tcctgcttct ccgcagtcgg tggcaatggc aaatgccagt
    11641 tgtatatatt cttgatagat tggagcaatg tctgctcctg catttctgac tgcttcggcc
    11701 agaaggtgca atgaagatag tggttccatc ggatttggta atttataatt agtaatttgt
    11761 agtcggtgat ttgcaatgac tcataattcg aagttcacaa cttttctgag cagtgctttc
    11821 gggtcatggc agaggaaaca ggcgcgtacg aggtctttcc ccgaagtgtc cactcctttt
    11881 ccgggttgtg tgttttcggc gtcatacatg cagtggacgt agttcatggc ccagcgcacc
    11941 gcctccgtgc tgtcttttcc gatagggcag ggtacaaaag cctttacacc tcgtccggta
    12001 gggctgatga acaccagtac cggtgcgagg taagggtctt tgaacagtag ttgcttcagg
    12061 cgtccggctt cgtcaggcga gtcgagatgg tctacgtcca ccaccatcag tccggagggt
    12121 agctttaggc agtcgctccg tcgtcgggtg aatacgccgc agggggtgac gtagggtaag
    12181 gtttgctgtt tcagcatccg gcagttgtta tcatcgcctt gtagggcagc ttcgcggatg
    12241 gcttgtgtta gggtgatcag ccgtttgttg gctgtgatga gttggtaaac ttcgttcagt
    12301 tctaaagtac gcaggggggt aagcgtggcg cttttcacga ttttcccggt cgctccgtcc
    12361 ttcatcggtg agatgggtgg catgaaaagc gacattttaa aagattttgg catattatac
    12421 gtttaaatag ttggctcaaa ggtattcatt ctctttcgtt gaatctttcc cacatgtaag
    12481 aaagatttta aaggaacaaa gtaaataata acaatatata acatagtatt ctatctaatt
    12541 acttaaaatt tatctaaatg ggcaaaaatt ttattcaccc ttcattgggc ttttttatcg
    12601 agcgaacgag aaaacagagt ggagtcacta ttgaaactct ttgcaaggat ttgcatattt
    12661 ctccatccac gtacatagac ttaaaaaaaa gggtgtaacg cctcacttag tacatacgaa
    12721 actcttctgc gatactatat cgatgaactg gaggaactgg atgatgacga aatcaggaaa
    12781 ttggctgggg aatgggtgga aaaatggctg gaggttagga agaaggggga gtggtgattg
    12841 gattggttga ttattactga taattaaagg aatctatata aatgattaat tttacagtag
    12901 gtctggtgca atcttctgat gctgtacagg ccataggtgc cgaacaggta ccatatttag
    12961 aacagcagag ttctcagaaa tgatgcttga gaatgaacgc cttgttaaga aatttgctaa
    13021 tgcgactaaa gatagtaagg ttgttttcat gacatgttct ggctctggtg gtatggaggc
    13081 tgccatcata aattgcctta cgccacagga taaggctctt gtaatcaatg gtggtagctt
    13141 tggtgagcgt tttgtggaat tgcttactct tcataaaatt ccttttacgg aaattaagct
    13201 taagtatggt agagctttga agcctgaaca tcttgctgaa tatgagagca agggttacac
    13261 tactttcctt atgcagaagc acgaaacttc tacgggggta cattacgata tcaatcttgt
    13321 ttctgatttt tgcaaacgta ataattgttt cttgattgtt gatacaatct ctaccttcct
    13381 ttgcgattca tttgatatgg tggcaatgga tgtaggggtg atgattactg gaagtcagaa
    13441 ggctcttgct tgcgctccgg gtattgcagt tatgattctt gctccttcgg ctattaaacg
    13501 tatagaaaag gtccaatgtt gctgtcagta tcttgatttg aagcttgctc ttaaaaatat
    13561 ggagagaggg cagactcctt gtactcctgc tgttggtatc cttcgtcaaa ttaatgtctg
    13621 tttaaaagaa attgagtctg caggtggtgc ggaggtggag attgcgcgtt gtgcagaatt
    13681 ggctaagtat tttcgtgata agcttgttaa gaataatctt ccactctttt gacttatcgt
    13741 caggttggaa caaatagctt tacagttaag tattatgttg agaagtttat tcttgacatg
    13801 aatacgatga agataattag ggttgacgag tatcgcgaca aaaagaagat taatcgtccc
    13861 gcaggttcgt tattctctgt agatggagaa atttatcgag tggcacaaaa atgcagtcgt
    13921 gcatatggag agtcgatctt tgtgtataag acaagtaaga attttgattt tattaaagat
    13981 aaaaaggtag cagaactcac tggtcagagt atagtcctga gtgatggtag aaagccgatt
    14041 ttgttgcaca cttattctca agcaggagga attgaggtga ttgactatag atgctcttta
    14101 taataatttg aaaaatgtta aataataatg gcaaagacag tttatcttgg tatgataggc
    14161 gatatcatgc atccgggtta cattaacatc attaacaaag ctactgagta tggcgatgtg
    14221 ataatcggtt tgttcactga taaggcgatt gctaaccacc gtagacttcc ttatctcact
    14281 tgggagcaaa gaaagaacgt tgttgagagc atcaggaacg tatcaagggt ggtccctcag
    14341 gatgattgga gctatgtctc taatctcctt aagtacaagc ctgattacat cattcatggt
    14401 gatgattggc aggttggtcc tgacaagtat atccgtgatg aggtattcaa agtaatggaa
    14461 aagttgggtg gtgaggttat cgagattcct tacacccaaa acatctctgc ttctggtatc
    14521 aaacaagaga ttgatgctct tggtgtaact cctcagatgc gtctttcttc tctccgtcgc
    14581 cttattgcag ctaaaccgat tgtacgtatt cttgaaagtc acaatggtct tactggcctc
    14641 atagcagaac atactaaggt agaggtgaat ggtcaggagc gtgaattcga tggcatgtgg
    14701 gcttcctccc ttaccgactc tacctctaag ggtaagcctg atattgaggc tgtcgatttg
    14761 actacccgtc tccatgacct caatgatacc cttgaagtaa ccacaaaacc tgttatcttc
    14821 gatggcgata ctggtggcaa gattgaacac ttcggtttta ccgttcgcac ccttgagcgc
    14881 ttgggaatct cttgcgttat aattgaagat aaggtaggtt taaaacagaa ttcacttttt
    14941 ggtactgatg ctgtacagac tcaggataca atcgaaggtt ttcaggctaa aattcgtgca
    15001 ggtaaggaag cgcaaattac tcgtgacttc atgattgtca gccgttgtga gtctctcatt
    15061 gctggtaaga ctgtagatga tgctttggag cgttgtcatg cttacgtaga ggcaggtact
    15121 gacggtataa tgatccactc caaagagaag tctggagagg acatcaagga gttttgcttg
    15181 cgctttcgcg agaagaatgc tcatactcct atcatcgttg tgcctactac ttataaccag
    15241 ttcacagaag aggaacttgc tgaatggggt attaatgtag tgatttatgc taatcacatg
    15301 cttcgttctg cttatcctgc aatggttaaa tgtgcagaaa ccatcctcta tactagccgt
    15361 tcgcttgaag catctgagca gtactgtatg cctatcaaac agattcttaa tcttattcca
    15421 ggcacaaaga agaagtaaac attaatttct taccccttaa actattttac aaatggtaag
    15481 acccgaattt tttgtaaata tactcaagga acaaggcata gacttttatg ctggtgttcc
    15541 tgattcgttg ctcaagaaca tttgtgcata tattaccgac caccttcctg ctgagcagaa
    15601 tattattgct gctaacgaag gaggggccat gggtattgct gtaggttatc atttggcaac
    15661 aggtaaggtg cctgtagttt atatgcagaa ctctggtgaa ggcaatatca ttaatccgtt
    15721 tgcctctctt accgacaagg acgtttataa cattcctgtg ctcctcgtta tcggttggag
    15781 agggcgccct ggagttcacg atgaacctca gcatgtgaag caaggtaagg tgacaatcgg
    15841 tttgcttaat accatgggta tcaactatgc tattctgcca aaggatgaag agggagctgc
    15901 aaagcagata aaaatagctg tcgacttcat gaaggcaacc aacgagtgct atgcccttgt
    15961 gatagagaag gatactttcg atacctataa gcttcagagc gttgaggtaa acgaactggc
    16021 aatgtctcgc gaagagacga ttcagaaggt ggcttcaaac attgaagata atgcttgtat
    16081 cgtatcaact actggtatga tttctcgcga gctctttgag gcacgtactg cttggagcca
    16141 aggtcatgaa cgtgatttcc ttactgtagg ggcgatgggc catgcttccc agatagctct
    16201 cggcatagct ctccaaaagc ctgagcgtcg agtatattgt tttgatggtg atggagccag
    16261 catcatgcac atgggtaata tggctattac agccagcatg aaatgcaaga attatgtgca
    16321 cattgtgttc aacaatggcg cacacgattc tgttggtggt cagcctactg ttggtctcaa
    16381 gattgatttt tgtgcaattg ctcaagctgt aggctacaag gctgcttata gtgtagaaac
    16441 tatggaggca cttgaagcaa aacttgcaga attcaagaac gcagaaggtc ctgttttcct
    16501 tcagatttgc gtaaaaaagg gaaaccgcaa ggaccttggt cgtccaacta caactcctat
    16561 tcagaacaaa gaggctttta tggaatttct taacaagtaa agtatgaaag taattctgtt
    16621 tgctgatata cacgccaatc tttctgcttt tgaggcggtt ctagctgata ttgagaaaca
    16681 ctatcagcca gatgccatga ttagtctagg tgactttatt gactatggta tgcgttcaaa
    16741 tgaaattatt gaacgtatac aaactgttaa tattccatta cttgccaatt tgaagggcaa
    16801 tcacgagaag gctttgattg atggggaact ctcatgtttc tcttcagaaa gagctcgtgt
    16861 gatgtccaaa tacacaagaa accatctcac tcagacatct attgattata taagcaatgt
    16921 gatgcaagag ccaatgcaag agttggaaat tggtggtaag aaagtacttc ttttacatgg
    16981 aactattgat gatccctatt ggggaaaact gactccagca aaagtggaag atgaaaagta
    17041 tcaggatttt gactacgtat tgagcggtca cattcatcaa ccttttaaga tagatgtatt
    17101 cttcaaagtt gacaatccaa tcatgcgcaa tcagaaacgt acgactttta tcaacccagg
    17161 ttcagttgga caacctcgca atcagaatcc atatgcacaa tatgtgtata tcaattttaa
    17221 aacgggggaa acccatttca atgcagttcc ttacgatatt gaagctgaac aatctctttt
    17281 ccccaaagag atagatactt tttacagcga acgattaaaa tttggaatat aaatgaagaa
    17341 cttatatgta ataagtggtg ttactggcat gacgggtagt gaactgtctc gtcagtttgt
    17401 ttctcagggt catacggtaa tcggtttcga caacttcttt gcaagttcta ttgataccgt
    17461 taaagacatt attgacaatc cctcgttcat cttctataat tacgacatta acaaagtcgc
    17521 tcagatggat gaagtatgcg ataaggcgaa agaactcaaa attgagtgcg atggccgtct
    17581 ggtgtttatc aattgtgctg ctgttgtcca tacaaagcat ttctatgagg tagagagtac
    17641 ttttcagact aacgtccttg ctatgaagga tttcttggag cgtgccattt ctatgagggc
    17701 tgatacttac attaattgtt caacttcgga ggtttactca atgcagtctt ggaatgagaa
    17761 tggcggtgtg aaagaatctg attatttggc aatgtcaaca gcggaacata gccaacgtac
    17821 aagttatgct tgcggcaagt tgatgactga attctttatg aaagatgctg ttggcaaggg
    17881 acgaattaaa ggttgttcta ttcgctttgc taatgtatat agcaggcacg agcgttttgc
    17941 agagcacatt atccctcata tcattgataa tctgcttgaa agccataccg taacccttct
    18001 tgaaaactcg aaggtgaaca aacgtacctt ccttcataat attgatagct gtcgtgccgt
    18061 tatggagctc atcgcttctg aggatgctct tgatggtact gtttataatg tggctactga
    18121 agaggaaatt gccattattg atctagtcaa gacgattgca ataaaaatgg gcatcaacga
    18181 tgtggatatc cgtttcgaag gttaccgaaa gtctgatcct gagcgtcgat tgctcaatac
    18241 ggacaagatt cgtacccgta ctagctggaa acctatcatc actctcgatg aaggcctcac
    18301 gatgtgtgtt tcaggtatca agaaatgaaa tatttgatta taactgttgc tggaacggct
    18361 acgcgtttta atcgcgacac taaggaagaa accctcaaat gcttgtatta taccgatgaa
    18421 cctcaatacg ctcttcttgc tcaattgctg aagaattgtg gtgagtacga taaatatatc
    18481 cttgtggggg gctaccttta tgagaagttg ggaagatttg taaagaacga actctctggt
    18541 tatggcaaaa aaatagaact tgtttacaac gagcatttca aagactatgg ctccggctac
    18601 agtttataca aaggtataga ggcaataaag gaggcaggtg atgtgacttt cgtagaaggc
    18661 gacttgttct ttatggctac agatttcagg caagtgtata attcgccaaa gagtgtgatt
    18721 accattaacc gagaaccaat ctactcgaat aaggcagttg cgttatacat taacgttgat
    18781 ggcaaaccaa ggtatttata tgatacgaat catcagacat taactgtatc agagccattc
    18841 aaggcaatct tcaacagtgg tcagatgtgg aaattttctt catctgagag gcttttgaag
    18901 actgttgatt cgcttacaaa agaacaactt caaggtacta atcttgaaat aattcaggct
    18961 tactttagtg atatgaatag tgaagagtat gatgtagtga ctttcactga ctggttcaac
    19021 tgcaatactg ttgcagatta tgatattgta agaaaattga tgtaaaaatg aatatggctg
    19081 tattagaaag agattacaga atagatggaa taaaatggtt gctcattgta ttggttacat
    19141 tcggtcatgt aatagaacct gctttaagca atcctattgc caataagctc tattctataa
    19201 tctacatttt tcatatgcca ttattcgtct ttatcagtgg ttattatgca aatgttaaga
    19261 ataaagaaaa actgattagt aaaggtttta tgcttttgga aacatttttg gttgtgatga
    19321 ttcctcaatg tttttattat ggaagtatca tccctttact aaatccggag aactcaggct
    19381 ggtatttaat cagcctaata acttggtata ttatttttct gttgattatc aataagctag
    19441 ttggcaaaat tgtcgtacaa tataatgggt gcgggggcag ttattgatat tcagttgctt
    19501 gttggccgta tttgcataca tgcttccgtt gaaacaattt ggtaacctgt tatcgttcca
    19561 acggtcgtgt atgtttctac cattctttat gatgggtttc ttgagaagag taaaaggcct
    19621 gcctattatt cctgatgttt caaaatgcat aaagcttgtt ttggctatag cctctttagt
    19681 atgttttgct ttttgtctca tctatagtgg ccgtatacta catgtattag agtttaataa
    19741 tgccaatgtg tggcacatgt caaatttgta caatcaaaat ataggaatgc ttcttgtttt
    19801 gaaagtattg gtttatattg gatcaattat tactacattc gctgttttaa tgtttgtgaa
    19861 cctccccaag tcgatatgtg cttatggatc aaagacttta gcatattatg taatacaagg
    19921 catgtttgca cacatattat caacctattt gcaagttaat ttttaccagg ccttgtttct
    19981 ctgtgtttgc atattagtcc ttacaacagt tctattacga tttgttgatt ctaaatttat
    20041 tacaaacccg ttttctactt tattaaaatg gaaatactga acagaaaact ttcccttctc
    20101 aaagggaagg ttgaaaatag tcagccaata actattatga ttattggttt gggtagcgtt
    20161 ggatgctact tgttggatta tcttgtatca ctaggtgatt cacaacttcg tcttgttgtg
    20221 gtaggacgta atgcagaaaa gatgcagatg gatataaata ttattcgtac tgcttcaacc
    20281 attcgtcatc agtgccgtag cgagattaag gtggttgata actgcgacct taacgatgtg
    20341 aacagcattg cagctgtact tgaagcagaa aagcctgact tcatagtaaa tagtagtcga
    20401 gtttactctg gtttgaagta tggtagcatc tcatggagta atcttcgtgc atacggcatt
    20461 tggactccgc tttctattcg atatgcaaag aatataatgg aggcatacga taaggccaac
    20521 tgtgaggcaa tctcaatcaa tacttcatat tccgatgctg ttattccttg gctaaagtct
    20581 gcgggtaagg cttattttga ctttggtagt ggtaatttga atcatcttgt gcctcgtata
    20641 aaattctata ttgcagagaa atatggtata aagaatttta atgacattga tgtaactatt
    20701 gcggtatcac attttcatga tgttgtcatt tctaaggaag gtcatgcaga aggtcaggac
    20761 atcttgcttg atataaagtt tcaaggcaag gatatggatt ttaataagga agaacttctt
    20821 aaatcctgtt ctatagcaat gcctgtagat cagaagcgca atatgatgaa tgcttccagt
    20881 aattttgata tcatattctc tgtgcttact gctcttcgag aggaaaaaca agtcaaaata
    20941 catactcctg gggtaaatgg tgaaattggt ggttatccta taattattga tggagtaact
    21001 gctactgcca agtttgatga gtctgtatgg actatagacc agatgcgtaa agctaaccgt
    21061 gagtcaattt attgtgatgg agtagagaat ataactgacg ctactctcgt ctatactgat
    21121 gaacttgtag ctaaggtaaa gaagtcgttt aatgttgatt tgcctaagtc ggtaaagttt
    21181 gtggatattg aaaatgtagc agatttaatt atcaatcaga taattaaacc tcaagtgttt
    21241 atttttgtgc aataatttgt aaactaatgg cagataatag attgttgtta attttctgta
    21301 taatctttaa cttatagttt tatgatatac acagctatgt aagcacttta aaaagttcaa
    21361 aatgaaatgt tagccttcgt tgtaaattaa aattagcaag atatgtatag cagcgaagat
    21421 ttagcaagtt tttattttca gtaccagacc aaggctttac ctcatgtcaa gttcctccag
    21481 tccttttgta tgaagcataa agttcctata atatttttca taagtggtat aaggatacgc
    21541 gtaataaaat aattacagtt ctatatctcc gattgtcaaa tgaaaaatgt aataaatatg
    21601 gatatcacaa caaagataaa aagaagtaaa ttactttatt acgtctacta ttacgtaatg
    21661 tcaggtttgg taaatttgta caagttgttc ttgaagccag atggtaaact catgcttttt
    21721 gtatgttatg gtggacgtca ttattccgat agtacgcgag tgatttatga ggccatgttg
    21781 aaggatgaac gtttcaagga ctatatagga ttacgacaaa ctgattgctg catttattga
    21841 tttaagagaa aagcgattta tctaaggtta tgaagaaagt tattaggaac atacgatttg
    21901 tttcatcagg ggcattataa cctcttaaaa cgtgcgaaag ctttaggtga ttacctcatt
    21961 gtgggtgtta ccacagataa tttcgacttg gagagaggca agatgaacac gtgcaataac
    22021 gtgatggaac gtattgaagc ggttaaatcc actggtcttg cagatcaatt gtgatagaag
    22081 aatatcgtgg gcagaagatt gatgatatac agaaatatgg agtggatgtt tttgcaatcg
    22141 gttcagattg ggaaggctat tttgactatc tcaatgagtt ctgtaaagtc atttaccttc
    22201 ctcgcactca gggtgcctca tctactttgc ttcgccagaa gcgtcctatt gttaatattg
    22261 gcattattgg tactggcagt attgcttcac gttttgttcc agagccgaaa aatgtgaata
    22321 gtgcgtccgt tt
//
