LOCUS       c00002_gnlPro..        14833 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MPHMGNDE_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:02:36
            Original ID  :: gnl|Prokka|MPHMGNDE_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 181698
            Orig. end    :: 196531
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14833
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[191698:194669]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12971
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14833
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14833
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             591..2303
                     /locus_tag="ctg2_129"
                     /transl_table=11
                     /translation="MKKFLLSSIFLFSLAYGVIACTEGLPTDNWEEPVVPVDPAVTTLR
                     GSFESKFVRYSKGQQHEAQMEEAKIVTLWKDTLWQNDRTHKQIVLWSGDKKYDDLTYEV
                     SDLVSDANSISASNIRLRFPSYIKGDDQALDCGNYESRTTTLIADALSEVPVTTLTTYP
                     VKIWVTINTPADAVPGIYTGTIQVKSANEVKQKFNLELLVVDHQLPAVADWSFHLDLWQ
                     FPFQLTTLCRDNGENVVPFSDEYFAMMKPFYQLLADAGQKVITTYIKDGAFNSGQTMVK
                     WSKNSSDEWIFDYTDFDKYVGKMMEWGINKQISCFSLAGWKTSVGYKDASGTDRTLELT
                     IGTEEYNTVWSAFLTSFKTHLQEKGWFDKTVLYMDEIKEDGMKSIIALIKENDANWKIG
                     LSGGNVDSGIENSLYDYSTILGYERQSDNAVSTFYTSCSQQYPNNYVTAQTNPAEMSWM
                     AWYALAKGFDGYLRWAYDYWTQSDPTSAQDGSNASGDFNMIYRSENTAAAVPISSIRLE
                     LLREGIQDFEKARILNNGQLDAAIRNFTSASGREAAKWVGIAEGTLKELSAND"
     CDS             2317..4392
                     /locus_tag="ctg2_130"
                     /transl_table=11
                     /translation="MKKLKNKIAFVLLFILVSAMSQAKGLDPRFQILPLPQNIEILKGQ
                     GIAGSELAYIVSKGESKIPVLGTLLDALPRIEKQGAGITLSLSEQNTPESPEGYTLEIT
                     SRGVTIQSRGQAGLFYGCQTLEQLMEDSRDLRIPIPCLRMTDYPEISYRAVHFDTKHHL
                     DRTEYYYRTIDKLARYKVNAIIWEVEDKLRYTRRPEVGAPNAISKQEMQAISRYAKERN
                     IEISPLVQGLGHAGFILKRHWELRENPHSDWEFCPSDPRTYELQFDLYRDAMEAMPDGK
                     YLHIGGDEITAIGIDERCKATGKTAFELQMIWLKKVCDFAVEHGRTPIFWDDMPLKYAD
                     LWWLLHRPLTDDEIRKDWNTSRLDEAIKMFPKNCIYMRWHYEDPTVLSHQMLLKWYHKN
                     GLNVMGATAAATGETPFMPRNNSRAQYIKDFCKLVSQNQLKGILATAWDDASAHWETVM
                     RGLIAQGEYSWHPDGRTVDEFIRAHARREFGLSGQQMEFLTEMEKAAFFFDQALVVSGT
                     RNPAWGVSETFRLLDLPDSEKPGEWKRKYQGRLDTARIESARYEKICKGLKVAEQAALR
                     NRYTLDIYKQTNELFHYPVKLLEVLEVYDSTKNDEERLQALVRIGDVCNSFKSMRAEFE
                     KTYSQTRFMESPEGYIADQNHHHHLSALSNNSDWIFLYEMPMVEKVERWLKEQKDN"
     CDS             4533..4667
                     /locus_tag="ctg2_131"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSKKLLELIDQKKELSSN"
     CDS             4685..4939
                     /locus_tag="ctg2_132"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYVSVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGDFK"
     CDS             complement(5096..5362)
                     /locus_tag="ctg2_133"
                     /transl_table=11
                     /translation="MLEILSHSSHFLPFLSPKRRREIGKTQPSFFDFSPHFQISPPIEA
                     DFRKYLLSLMCKRSKESDMDNLMRKLPIGIQTFEDIRRKNILL"
     CDS             5529..5861
                     /locus_tag="ctg2_134"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             5842..6147
                     /locus_tag="ctg2_135"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(6217..8331)
                     /locus_tag="ctg2_136"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     NYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETVSLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAEYLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(8418..8648)
                     /locus_tag="ctg2_137"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             8842..9345
                     /locus_tag="ctg2_138"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             9405..9572
                     /locus_tag="ctg2_139"
                     /transl_table=11
                     /translation="MKEIVSRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             9559..10008
                     /locus_tag="ctg2_140"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRPPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(10001..10729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_141"
                     /sec_met_domain="Radical_SAM (E-value: 2.6e-28, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10743..12971)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_142"
                     /sec_met_domain="Gly_radical (E-value: 8.9e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             13537..14760
                     /locus_tag="ctg2_143"
                     /transl_table=11
                     /translation="MERTTFCLLFYIRRTKLNRNGEAPIMMRITVNGVRVDASVKKTIL
                     PEFWSAAKGKALEKKREYKELNLYLDSIRLRIMKIQRELEIEEVSVSANSVLDRFQGKD
                     APVQRTLFEVFREHNDKCVQLSGTDMAPATVQRYETSLKHTRDFVWETYHKKDVLLDEV
                     SRQFIEDYEFWLKTEKKCCHNTATKYLKNFKKIIRIALAKGWMKNDPFLEIRFSLDKVE
                     PDFLEDSEIQKLISKEIDIPRLSQVRDIFVFCCFTGLAFSDIHGLRKEHIVEDSNGVRW
                     IRKGRQKTKIMCNIPLMEIPLKILEKYSTNEYCKKHGVLFPVLCNQKMNAYLKELADIC
                     GIKKTLTTHVGRHTFATFALANGVSIESVAKMLGHTNVQMTRHYARVLDRTVIREMSQI
                     KMDFHISI"
ORIGIN
        1 cattacctat aataatctgt ttgaaggata tatagacttg acaaatacga gctggaacaa
       61 catcggcttg gtgcaatccg accagtccgc ctattttgat gttagcgccg gattgggcgg
      121 cggacaatct tatggaactt tagcgatggt ggagaaatcc tctccgggaa ccggctatta
      181 tccgtgtgac ggtccctggg gagattggac aactgatgga ggtaatgcct cgattgtttc
      241 tcccggcatt tggaaagtta attttgacct cactacccgt cagatcgttt tactggagac
      301 acaatgggct gttacgggga cagccgcagg aacggtgaaa gcaatggtct acaattctga
      361 cacccgcaag tggtctttga cgacagaact tgcagccgga aaattgaaat ttaccactat
      421 tccggtctct gccggtgatc cgactgtaac gtatggggcg tccgatggta ttgtcagact
      481 gtcggagaca gggacggata ttactatcga cgaagctggt acgtaccgga tagaattaga
      541 cttgagtaca cctttttatg attatactat aacgagataa atcaacaatt atgaagaaat
      601 tcttattaag cagtatattt ttgttttcac tggcttatgg agtaatagcc tgtaccgagg
      661 ggttgccaac cgacaactgg gaagaacctg tcgttcccgt agatcctgcc gttactaccc
      721 tgcggggttc gttcgaaagt aagtttgtga gatactccaa aggtcagcaa cacgaagctc
      781 agatggaaga agcgaagatc gtcacccttt ggaaagacac cctttggcag aacgaccgta
      841 cacacaaaca gatagtgtta tggtcaggag ataaaaaata tgacgacctc acttatgaag
      901 tttcggatct ggtgagcgac gcgaacagca tctctgcctc caatatccga cttcgtttcc
      961 cttcttatat aaagggagac gatcaggcac tcgattgtgg aaattatgag agccgcacca
     1021 ctaccttgat tgccgatgcc ctttccgaag tacccgtcac aacgctcacc acttatcccg
     1081 ttaagatatg ggtgaccata aacacgccgg cagatgccgt accgggcata tataccggaa
     1141 ccattcaggt gaaatcagcc aatgaagtga agcagaagtt taatctggaa ttgcttgtcg
     1201 tagatcatca gttgcctgcg gtagccgatt ggagtttcca tcttgattta tggcagttcc
     1261 ctttccaatt gacaactctg tgtcgggaca acggagaaaa tgtcgttcct ttctccgacg
     1321 aatattttgc gatgatgaag ccgttttatc aactgttggc agatgccggg cagaaggtaa
     1381 tcaccacgta tatcaaggac ggtgctttca atagcggaca aacgatggtg aagtggtcga
     1441 aaaacagttc cgacgagtgg atattcgact ataccgattt tgataaatat gtcgggaaaa
     1501 tgatggaatg gggaatcaat aaacagatca gctgtttttc tttggccgga tggaagacgt
     1561 ctgtcggata taaagatgcg tcgggcacgg accggacatt ggaactcacc ataggtacgg
     1621 aagaatacaa cacagtgtgg tctgctttcc tgacttcttt caagacgcat ctgcaagaaa
     1681 aaggctggtt tgacaaaacc gtgctttata tggatgagat taaagaagac ggtatgaagt
     1741 caatcatagc tttaatcaaa gagaacgatg cgaactggaa aataggactg tcgggaggaa
     1801 atgtcgacag cgggatagag aacagcctgt atgattattc gaccatttta ggctacgagc
     1861 gccagtcgga caatgccgtt tctaccttct acaccagttg ctcacagcaa tacccgaaca
     1921 actacgttac ggcgcaaacc aatccggcag aaatgtcgtg gatggcgtgg tatgcgctgg
     1981 caaaaggatt tgacggatat ctgcgctggg catacgatta ctggacacag tctgacccta
     2041 ccagtgcaca ggatggaagt aatgcgtccg gcgatttcaa tatgatttat cgcagcgaaa
     2101 ataccgccgc cgctgttccc atctccagca tccgtctgga actgctgcgg gaaggcattc
     2161 aggattttga gaaggcacgt atactgaaca acggacaact ggacgcagct atccgcaatt
     2221 tcacctctgc ttcggggcgt gaagccgcca agtgggtagg aatagccgaa ggaacattga
     2281 aagaactatc tgcaaatgat taaacagaaa tagataatga agaaattaaa gaataaaata
     2341 gctttcgtac tgctgtttat acttgtctcc gctatgtcgc aggcaaaggg attggaccca
     2401 cgttttcaga tactcccttt accccagaac atagagatat tgaaagggca ggggatagca
     2461 ggtagtgaac tggcatatat cgtatcgaaa ggcgaaagta aaattcccgt tttaggaaca
     2521 ttgctggacg ccttaccccg cattgaaaaa caaggagcag gtattacact ttccctgtcg
     2581 gaacagaaca cacccgaatc tccggaagga tatacgctgg aaatcacatc ccggggagta
     2641 acgatccaat cgcgtggaca agcaggattg ttctacggtt gtcagacctt ggaacaactg
     2701 atggaggata gtcgtgacct tcgtatccct attccatgtc tccgaatgac ggattatccc
     2761 gaaatctctt accgtgccgt tcactttgat acgaagcatc atctggaccg gacggaatac
     2821 tactatcgga ccattgataa actggcccgc tataaggtga atgccatcat ttgggaagtg
     2881 gaagacaagc tgcgctatac ccgccgtccc gaagtgggcg cccccaacgc catcagcaaa
     2941 caagagatgc aggctatcag tcgctatgcc aaagaacgta atattgaaat cagtccctta
     3001 gtacaaggat tgggacacgc cggctttatc ctgaaacgcc attgggaact gcgggaaaat
     3061 ccgcatagcg actgggagtt ctgtccttcc gacccgcgta cctatgagtt acagtttgat
     3121 ctttaccggg atgcgatgga agccatgcct gatggcaagt atcttcatat cggtggagat
     3181 gaaataacgg ctatcggcat agacgaacgt tgtaaagcga ccggaaaaac agcttttgaa
     3241 ttgcagatga tctggctcaa aaaggtttgc gactttgctg tggaacatgg cagaactccc
     3301 atcttctggg atgatatgcc tttgaagtat gccgaccttt ggtggttgtt gcatcgcccg
     3361 ctcaccgatg atgaaattcg taaggactgg aatacctccc ggctggacga agctatcaag
     3421 atgttcccga agaattgcat ctatatgcgt tggcattacg aagaccctac cgtcttgtcc
     3481 catcagatgc tcctgaaatg gtatcataag aatggactga atgtaatggg agctaccgca
     3541 gcagcgaccg gtgaaacccc gtttatgcct agaaacaact ccagggcaca atatattaaa
     3601 gatttctgca aacttgtttc tcaaaatcag ttgaagggca tccttgccac ggcttgggat
     3661 gatgcctctg cccattggga aacggtgatg cgcggactta tagcacaggg cgaatatagt
     3721 tggcatccgg acgggcggac tgtggatgag tttatccggg cgcacgcccg gagggagttc
     3781 ggcttgtccg gtcagcaaat ggagtttctg acggaaatgg agaaagctgc tttcttcttt
     3841 gatcaggcat tagtcgtttc cggcacgcga aatcctgctt ggggagtatc ggaaacattc
     3901 cggttgctgg atttgccgga ttcggagaaa ccgggagaat ggaagcggaa atatcaggga
     3961 agactggata ccgcccgcat tgaatcggcg cgttatgaga agatttgtaa aggcttgaaa
     4021 gtagctgaac aggcagcttt acgcaatcgc tacacgttgg atatttataa gcagacgaac
     4081 gaactgtttc actatccggt gaaattgttg gaagttttag aggtttatga cagtacaaaa
     4141 aacgatgaag aacgtcttca agcattagta aggataggtg acgtttgtaa ctccttcaaa
     4201 agtatgcgtg ctgaatttga aaagacttat tcgcaaactc gttttatgga gagtccggag
     4261 gggtatattg ccgaccagaa ccaccatcat cacttgtctg ctttaagtaa caacagtgac
     4321 tggatatttc tgtatgaaat gccgatggta gaaaaagtgg aaagatggtt gaaagaacaa
     4381 aaagataact aaccttagat tttaaatatc gtattgttct gttgaggaca atacagcgta
     4441 gtgtttttga aggtattagt caccatttcg ggaagcaggc aatagctgtg ctttccggaa
     4501 tggctttttt ataattaata aaaatcgttt ttatggaaaa ttcattgagt gatgaattgt
     4561 tttgttcatt gaagaatgaa cttcgtgaag tagatgcaca aatcagtgtg catagtaaaa
     4621 aactgttgga gctgattgac caaaaaaaag aattgtcgtc caactgattc gggaagaaga
     4681 acaaatgacg cccactgtta tcgaatatcg gggagatccg aaacggtatg tttctgttat
     4741 tctaggtgcc attgaccggg ggaggttgac gtataatgga gacgcgaatt gcgaacagac
     4801 gttccggtcc ttgtcaagtg tgatagatgt cataagccct aagaacggga aagcgctcag
     4861 tatcgaaacg ttggtttcgt atgagaagaa agaacgtgcc ggagagtttt cagattattc
     4921 ggaaggagat ttcaaataat ctgtttccat cgctgaacgg ttgaattaaa aaagtggcgg
     4981 aaatctggat ggaaacttgt tgcagattgc cgccacttgg gtttctatta cttaatagtc
     5041 tctattaacc aacggtttaa gttccggctt tctgcactaa attccactcc gatctttaca
     5101 ataagatatt cttccttcgt atatcttcaa aggtttgtat tccaatagga agtttacgca
     5161 tcaagttgtc catatctgat tcttttgatc ttttgcacat caaagataac aaatatttcc
     5221 tgaagtctgc ttcaattggt gggctgattt gaaaatgcgg tgagaaatcg aaaaaagacg
     5281 gttgtgtttt tccgatttcc cgccgtcttt ttggagaaag aaaaggtaaa aagtgagagg
     5341 agtgagagag gatttctaac attcgtattt tttttagaga aatatagaaa gtagaaataa
     5401 agaaataaaa tagaaaaagt ttcaattcct ctctcactcc tctcactttt gtgggtgaag
     5461 atgatgaaaa ataatataaa acgagggaat atgttgtata gttgaacaac gtttcttata
     5521 tttgcgttat gaaaagagaa ataatagcat ataaaggata cttcaaagaa ttctttgaaa
     5581 atttagatgc tggcacccaa gataagatat tgtatgtgct aatgttattg cagacacaag
     5641 acagaatacc tttgaaattt atgcggttga tagaagaagg actttatgaa cttcgtatcg
     5701 agtaccaaag caatatatat agaatattct tttgtttcga cgaagggcgt attgtgattc
     5761 tgtttaacgg ttttcaaaag aaaaccgaaa aaacaccaaa gaaagaaatt gataaagcaa
     5821 agatattaag aaaggagtat tatggaagca aaaacaaatg aggaattctt taatgtcagt
     5881 gcattaatag atgagcgttt tggtaaggaa ggaacagctt ctcgtgcaga ggcagaagaa
     5941 aaggcctacg ccttttatac aggacagatt atcgaggacg caagaaaaaa ggctaaaatc
     6001 actcaggctg aattagcccg gcgtatcggt tctgaccgtt cttatatttc aagagtagaa
     6061 agtggtcaga cagagcctaa agtatctact ttctatcgta taatgaatgc gttaggctgt
     6121 aaaatcgaat tttcaatgat tttgtaaaaa caataaatgc agagtatctg tcaagatgac
     6181 tctgcatttt gctatattca caaggctttc ccgcttctat tcatacagcc tgtttgattt
     6241 tacctgctcg atatctataa taaatacggc atatcggcgc ccgttatttc cttttttaga
     6301 ttcaaaatgg tgcttagtca tcaccttccc caactgtatt tttgatccga tggaatactg
     6361 ataaccggta cgctcacgta ttagttccgc aatctcactg acagtcagat aataaacctt
     6421 ctcgaaacgt tccggcttgc ggatatgcgt aagaaccatt tcttcttccg gtgaatgaaa
     6481 gatgaaagcc tcgttattct cttcaagccg ttcattgtcc gcttgcgtga accagtattg
     6541 atatcccggc ttattcagca gatatttgat ctgagcatag agctgcgcat aattgatggt
     6601 aataaattgg atggaataag gatgaaaaca aaggaaacgc cggttgcctg tcgtgtcgtg
     6661 aagcacttcc tgataattgc aggttcctgc aaaagaggcc gtatgaggga agttttgcga
     6721 acggcgtgca taaggcagac ggaaactgat cactttgcgc gttaccaaat ctttgaatgc
     6781 attcagttcc cggccgctca tcccttcaaa ctcgtcgaga ttgatcagca tagcctgcgt
     6841 tattttggct aaatcatctt tattgttcga attgattagt ccggtagaga gataagcacg
     6901 cagttcggga ggcaggagat tattgataaa ggtagtcttt cctatgttct gtatctcgct
     6961 gcatagcaga agtaccgtgt gattgacaat attctcctga gtagccgctg cgcacatcgc
     7021 caccagataa cgttccaggt attccgccca aaactcctga tgactcgtct ggacactatc
     7081 cgccaggata cggatataat cggttccgtc ccattcgggc agtaattcaa aatactcgcg
     7141 aatgggatga tacgactggc tgaaatcgga gtaaatcaga ttttcgattg ttttgacagt
     7201 gcagggatat cccagttcgt tgatttctat ccagatactg ttttccatca tctcatccaa
     7261 gatgcggaaa ggctccggtt tctcggtgtc gggatgcctt ctgcgatatt ccatgatatg
     7321 cagcacttcg ttgtagcgtg tttcgtagtg ctcgctgata tattgctcta tccgtaatat
     7381 tcgtttctgc gtgccattca gtttacaggt attaaattcg tcggtatgag cgtaggcgct
     7441 attgatcaaa gagactgtct cgtctgccgg aaagtctgta aactggcttt tgataaaagc
     7501 ggatgcttcc tcctgcggaa tgccgtagcg attgaaggta catgagagat ggtgcagata
     7561 attgttccgg ttgcctgcta tgtatttttc ggacttgttg tgatagtagg ttaaagtcag
     7621 caccagagaa gcgttggcgg aatgggcgtt gagcgctgtg tcttcattcg tcggggggcc
     7681 gtccggagga gtctgttgtt tactgccgga gagattttta cgatttgaaa ccttgtagga
     7741 tgcctgaggt tgatctacaa gaaaagcgtc agcgttcgga ttgaaataaa tctccggatc
     7801 gtaagagaac agacaagtgc gtgctacatc ctggccggag gtgtcgattt ctatctgaca
     7861 gagttcggtg taaaaagaaa cgagtctggt gtaagctgca tgatggaagt cttctatttc
     7921 ctgaagggtt tcgggcaatg tctcatccgg atggcatgcg cgtactatga ttttcacgcc
     7981 catccctttg ggactgataa aggcgatgcg ggtgtaattg catctcttga tgatagggag
     8041 gatgcgtgcc aattcttctt tgctgaggtg gtcgatgtct atcacgatgt gtcccagata
     8101 tttgacgagg ttcactttgg tacgccttcc tcggtagctg gcggagaagg cgattgccgg
     8161 caattctttt ttcttctcat tggcagcctt ttctccttgc tctgcaaaga tgcggcgtat
     8221 ttcttcgact ttttcccggt aggtaaaact gccgatagtg gacactattt cttcttcggt
     8281 catctctgct attgcgtagt agaaaccttg aaatatggtg aaatgtttca tttttatttt
     8341 gattattgtt tgtcgatgca aaggaacttc tttgcggaaa tgtgtaaagg aactttgtat
     8401 aaaatggcaa taagttacta cggttcgccc aaaaagtgta tgatagttgc cacttgtttc
     8461 ggcgaaagga gacggttgcg tgcgcggtag ccttcctgtt cgagttcgtg caggagaggg
     8521 aggttgtaaa taatccaacg acgaagtatt tgtaaagcaa ctttgaggca gacatgggga
     8581 ttgtaaaggt gagccagttc cgctttggta taggtgcgga taaggaaaga atcttctttg
     8641 taattcatga tgttttcttc ttgttttatg ctataaagtt acataaaatt ccttgttttt
     8701 caaaggtttg acttcgtttt tattcgttgg gaatcaagaa acttcgttgg ggaatatagc
     8761 ttgtccggct atccttatct ttgtgctgtt aacaagaagg ggatgcatcc tatgtattat
     8821 aaactttaaa attattttat tatggcaatg acagtatctt attcagtggt gccgcgcaag
     8881 aatcctgcaa aaaagagcga accggcaaag tattatgcac aggcgcaggc gtcgggagag
     8941 ttggactttg aagagttgtg cgaagcgatc accagtcgtt ctacttgtac ggaaacggat
     9001 gtacgtgcgg ctatttcggg tattctttac gaagtgaagc gtgcgttgaa ggcaggaaga
     9061 attgcgagac tgggcgattt gggcagtttg cagataggac tcaacagtga aggtgcggca
     9121 tcggtcaagg aattttccgg ttcaatgatt aagggggcgc atcttatttt ccgccccggt
     9181 aagacgctgg cggagttgat gaagattctg agttatcagc aagtgcagac tcgtgcggtg
     9241 gcgcaggcgg gtgcaggcga tggcggggga gaagaccctg acaagaatcc ggattccggt
     9301 ggtgatggct ccggtgatga agaggctccg gaccctacgg tataattggc agacgggtca
     9361 aggtaataac gaattagaat aacttccatt aatattttga taagatgaaa gaaatagtaa
     9421 gtcggatttt agatgtgatc atgtatctga ttcctttctt cggaaagaga aagcgggaca
     9481 gggtggtgag agaagtgcgc tatcatacta cttgtaagga ggtgtgcaaa gtgaaaacga
     9541 cggaaaggga aaaggaacat gagaaagatt agtctgattg tgatccattg ttccgccacc
     9601 cgtgtcgatt gcgactttac ggcaaaggat gtggatacgg ctcaccgtta tcgtggcttt
     9661 tcgtgctggg gatatcatta ttatatacgc aagtcgggcg agattgagcc gatgcgggat
     9721 gaagatacgg tcggagctca tgcacgtggc tataatgcga tcagcttagg tgtatgttat
     9781 gagggcggtc tggatgagaa tggaaaagct gcggatacgc gtcccccccg tcagaaggag
     9841 gcgctacatc gcttggtaca cgaattgttg cagcgttatc cggaagctaa ggtagtaggg
     9901 catcgggatt taagtcccga caccaactat aatgggatcg tagatccttg ggaacggatt
     9961 aaagaatgcc cttgctttga ggtcattgga gaattctcca ttaattaact accaccgtag
    10021 tgaaatactc tttgaatacc tccgcagctt tttcaagctg ttcgggggta ttttctttta
    10081 cccctttcat cttgtattcc tgtcccatcg cttcgtactt atgtacgccc agtgtatggt
    10141 aaggcagtat ttccacccgt tggatcatct tgtattttcc gagtgcttct cccagtgcgc
    10201 gtatgtcttc ttcaaaatcg ctgtatccgg gcactagcac gtagcgtagc cagaaaggtt
    10261 tctcctgttc ttccagccag gcggccgtgc ggatggtttg ctcgttgctt cttccggtga
    10321 gcgtttgatg gcggttaggg ttgaattcct ttatatccaa taacacaaga tcggtcagtc
    10381 tgaataattc ttctacgtct tcgttccaaa gtcctccgtt gctgtccaga cagacatgga
    10441 tgcctttttc tttcagttcg cggaccagcg ggacgagtgc tttcgcctga aacgtcggtt
    10501 cgcctccgga gaaagtgatt cctcctcgtt tcccgaagaa ggggcgctgg ctcattgcca
    10561 tgcggacgat ttcttccggt ggggtaggcg tgcctccctt tcctgctatc gtatccggat
    10621 tggcgcaata gagacagcgg aagttgcatc cttgaagaaa aacgacgagc cgtaagcccg
    10681 gcccgtcgaa tgttcccata ctttcgtatg aatgtacgtt tatcatcata tagagtaata
    10741 gattacatac gttcgtggaa gctacggctg ataacttcca gttggtgttc gcggctcagc
    10801 ttcacgaagt ttacggcata gccggaaacg cggatggtca gctgcggata gttttccgga
    10861 tgctccatgg catcgtacag catatcacgg ttcagtacgt ttacgttcag gtggtgggca
    10921 cctttggtga agtaaccgtc catcatcgtc acgaggttct cgatacggtc ttcgtccgta
    10981 gcacccagtg atttcggaac gatagagaag gtgttgctga taccgtcctg cgagtcacgg
    11041 taacgaagtt tcgctacaga gctcagagaa gcgatcgcac cattcttgtc gcgtccgtgc
    11101 attgggttgg cacccggagc gaaggcaaca cctttggcac gtccgtcggg agtagcaccg
    11161 gtctttttgc cgtacatcac attggaagtg atagtcagca aggagagggt aggacgggca
    11221 ttcttgtaaa caggcaattt cttcaattct tcgctgaaga agtataccag gtctacgcca
    11281 aggtggtcta ccttgtcgtt gtcgttaccg aagcaaggga attctccttc gatgtcgaag
    11341 ccttctgtca ggccgatatc gttgcggcgg gcagttactt tcgcatattt gatggcagac
    11401 agtgagtcga gtgcgatgga aagtccggca acaccgtaag caaggttgat gcgcgggttc
    11461 gtatctacaa gagccatctg ggccttctcg tagtaatact tgtcgtgcat atagtggatg
    11521 atgttcatcg cttcgttgta tacgcgggcg atttcggtca acactttctt gtagttgtcc
    11581 attacttctt cgaacttcag cgtgtcactg gtcagtacgg ggatgttctt caccatgact
    11641 gtaccggtat tctcgcaacg tccgccgttg atggcaagca acagggcttt ggccaggttg
    11701 caacgggcac cgaagaactg aatctgcttg cctatttcct ggtatgatac gcagcaggcg
    11761 attccgtagt cgtcggactg acgtacttcg cgcatcaggt cgtcgttttc gtactggata
    11821 gaagaagtgt cgatagaaac ctttgcacag aattctttga atccttccgg aagttccggg
    11881 ctccagagta cggtcaggtt cggttccggt gaagggccga ggttgtacaa tgtctgcagg
    11941 aaacggaagg aggtctttgt cactttggta cgtccgtcgt tgagacgtcc gcccagagat
    12001 tcggttaccc aggtcgggtc gcctgcaaag atgtcgttgt atgattgcat acgcaggtgg
    12061 cggaccatac gcagtttgat gacaaactgg tcgatcagct cttgcgcgaa cgattcggtg
    12121 atggttcctt tgctcagttc atattccaga tagatatcga ggaaagaaga aacgttaccc
    12181 agtgacatgg cggcaccgtc ttgttctttg acggcggcaa ggtaagccat atatacccac
    12241 tgtacggctt cttgtgccgt gtaagcggga cggctcaggt cgagaccgta gtattcgccc
    12301 atcactttca tgtctttcag tgccttgatc tgttctgcca cttcttcgcg cagacggatg
    12361 cgggcctctg tcatcggacc ggtgaggttg tgcaaatctt ccttctttgc ttcgatcaga
    12421 cggtcgatgc cgtaaagagc catacggcgg tagtcaccga tgatgcgtcc gcgtgcataa
    12481 ttgtcgggaa gtccggtgag gaatcccagc gaacggaagg aacggatttc ttccgtatat
    12541 acgtcgaata ctccgtcgtt gtgcgtcttg cggtagtgag tgaaaatatc ttttacgcgg
    12601 tcgtccactt ccacgccgtt ttcgtgacag gctttgctga ctacgttgat acctccgaaa
    12661 ggcttgatgg cacgtttcag aagttcgtct gtctgcaggc cgacgatcag ttcgttttcc
    12721 ttgtcgatat atccggcctt gtgggaagtg atggttgata cggtaacatt atctaatgag
    12781 cggacaccgt tgttttctct ttcttctgcc agtgcttcga ggcagcggtt ccatacggct
    12841 ttggtacgtt ctgtaggtcc ttcgaggaat gaagcatctc cgtaatacgg agtgatgtta
    12901 tgacttacga aatctctgac gttgatttcg ctgctccaaa gaccgtcttt aaagatcttg
    12961 tttaattcca taaaatgata aaattagagg ttgtagttat cctattcttt agagcgcaca
    13021 aagttacaat catttttcat atgatcagca taaatatgct ctattttatg cttttcaaca
    13081 taaaatacct attaattgct atccttagga aaagattaga ttaaattttt agtgaaaact
    13141 cttgcaagtt taaaatatct tcgtaccttt gcaccgcttt taacgaaaag cacttctgat
    13201 aaggaagttt tggagaggtg gcagagtggt cgattgcggc ggtcttgaaa accgttgtac
    13261 cgcgaggtac ccggggttcg aatccctgtc tctccgctgg aaagaattgc aaaacaaaga
    13321 aaatccctgt aaattaatac tttacgggga ttttttgttt ttggtacata gcaaaaataa
    13381 gcatatcaaa gcattctttc ggtgtactat tcggtgtacc tgattgcctt caatgccagg
    13441 tacacctatt aagtaaataa ttcattgttt atcagtgctt tgcatcttga cttgttgctc
    13501 ttggaaattt agttttgtga ttaaaaaaca agtaagatgg aaagaacaac attttgtcta
    13561 ttgttctaca ttcgtaggac gaaattgaat cggaacggtg aggctccgat aatgatgaga
    13621 attacagtga atggagtccg ggttgatgct tcagtgaaga aaacaattct tccggagttc
    13681 tggagtgcgg caaaaggaaa ggccctggaa aagaagcgtg agtacaagga actgaatctg
    13741 tatcttgact ctatccgttt gaggataatg aagattcaac gtgaactgga aatagaggag
    13801 gtatccgttt ctgccaacag tgttctggat cgtttccagg gtaaggatgc ccccgtacaa
    13861 cgtactctgt ttgaggtttt ccgtgagcat aatgataaat gtgtccaatt gtccggtacg
    13921 gacatggcgc ctgcaaccgt gcagcgttat gagacatcct tgaagcatac ccgggatttt
    13981 gtctgggaga catatcataa gaaagatgtt cttttggatg aagtttcccg ccagtttatt
    14041 gaggattacg agttttggct taagacagag aaaaagtgtt gtcataacac agccaccaaa
    14101 tatttgaaga attttaagaa gattatccgt attgctttgg ctaagggatg gatgaagaac
    14161 gatccgtttt tagaaattag attctcattg gataaggtgg aaccggactt tttggaagat
    14221 tcagaaatcc agaagctgat atcgaaggaa attgatattc cacggttaag tcaggtacgg
    14281 gatatttttg tgttctgttg tttcaccggt ttggctttct cggatattca tggtttgaga
    14341 aaggaacata tcgtggagga ctcgaacggt gtcaggtgga tacgaaaggg gagacagaag
    14401 accaaaatca tgtgtaatat tccattaatg gaaataccat tgaagatttt ggaaaagtat
    14461 tccaccaatg aatattgtaa gaaacatggt gtgctttttc cggtgctttg taatcaaaaa
    14521 atgaatgcat acctcaagga actggctgat atttgtggta ttaaaaaaac attgaccacc
    14581 catgttgggc gtcatacttt tgccacattt gctctggcca atggtgtctc gatagagagc
    14641 gttgctaaga tgttagggca taccaatgtc cagatgaccc gtcattatgc acgtgtgctg
    14701 gatcgtacag tgatacgtga gatgtcacag ataaagatgg attttcatat ctctatttag
    14761 aattatctag taggaggttg aattctaagt cctctccaaa caatatctat aaaatcttac
    14821 ccaagtttac gaa
//
