LOCUS       c00002_gnlPro..        13267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKMFCOIL_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:33:05
            Original ID  :: gnl|Prokka|AKMFCOIL_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13267
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13267
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[294:3267]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      295..3267
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13267
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13267
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             295..2523
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1"
                     /sec_met_domain="Gly_radical (E-value: 5.3e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2539..3267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_2"
                     /sec_met_domain="Radical_SAM (E-value: 4.7e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(3295..3738)
                     /locus_tag="ctg2_3"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDEDGKAADTRTSRQKESLHRLVRELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(3725..3916)
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MITLILDQMKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATH
                     KEVCNVKTTEREKDDEKD"
     CDS             complement(3913..4416)
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             4610..4840
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNPPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             4928..7045
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MDHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHTSLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRMLQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSITYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPSNKDDLAKIAQAMLINLDEFEGMSGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(7294..7599)
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTVTRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             complement(7580..7912)
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFDRLDTGTQDKILYVLMLLQTQDRIPLKFM
                     KLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIEKAKILRKEY
                     YGSKNK"
     CDS             complement(7969..8214)
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MSHLTPVTIEYRGNPKQYVSVVLDAINRGRLTYDGIANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             complement(8223..8357)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MENSCNDELFCSLKNELREVTAQINVHSEKLMELLDQKKESSVN"
     CDS             complement(8477..9748)
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MKRFILLTILCCLVLSISAQIARDEIFEDIHRSAANHYAYPDPHF
                     TMTAPPKGYKPFYLSHYARHGSRYRVNPDDYTKPLAILREAEKDGVLTDLGKKALWLVD
                     SLARGAENRYGDLTPLGARQHRGIARRMYNNFPEVFQGAAEVDARSTTVIRCILSMTAE
                     CLQLQSLNPELRIKDEATSYDMYYMNYGNEYFKKKRQEDEVIAVKAAFRKEHLHPERLM
                     KSLFNNDNYVKWKVDAGKLMSYLFELAAITQSHDTDLDLYSLFTKEECYDLWLISNLNW
                     YIDYGPSPLTQGKMPYVEANLLENILNTADTCVVKKENSATLRFGHETCLLPLACLLEL
                     GDCAYQTTDINKLSDIWRNYRIFPKACNIQFVFYRKKGNDNILVKILLNEQEMKLPLAS
                     ELVPYYHWEEVERYYRNKLATFVH"
     CDS             complement(9785..11056)
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="MDIKKIVNFIFLLVFSCIIKAQMTIPPFPKWEKGYLDIHHINTGR
                     GNCAFLIFPDGTTMMIDAGDFDGKEYAAKYAPMHAAPIFPDSSYTPGSSIINYVTNLLG
                     KDVVIDYFLLTHFHSDHYGDVQKATGTSKNGYRITGLTEVGDVIPIKMYVDRDYPDYQF
                     PVDLRSKNDGVDLPTFLNLLEFLNYQEKHNGLKVEKFDIGSNTQFVLKKEPKSYPGFEV
                     RNIKSNNRLWTGEGKKTTILFTKEELMAKNGKYSENQMSTAIVVKYGAFKYYAGGDNSG
                     LVDQDHAEWYDIETPMAPIIGKVSAVSLNHHSNRDATNRNFLEVLDPKVVVAQSWSTDH
                     PGAEVGQRLLSKNIGTQPRDVFMTYYDDETGVAIGPWFARSLKAKQGHIVIRVYPDGEY
                     EVYVLDARKTDLVISNRFGPYSSE"
     CDS             complement(11093..11944)
                     /locus_tag="ctg2_14"
                     /transl_table=11
                     /translation="MKYLNILLIILPFIFSCSSDTPENDKEKIPPIIDTSIRVGTFNVD
                     VGQTATAEEIALSLKSFYLDILSLEECPILIDKNSGVEEFYSIIGKALGMEYFYIGDIS
                     SGNHWIEWGKDKTGKYAGKYKVILSKTPILQSKEFALEGKGWTHSSTIRIETKIKNKEL
                     TFYSLHIPGSAGVVEGSVMKNLVDVVLMKDTSKRIIVMGDFNDLPETNAMQYIFNSGFK
                     SVWDDVEDAEQYIDKYKYGQIDNILINKNSGMKAEIAYSIFKKDISLSDHPFLWSKIII
                     GE"
     CDS             complement(11954..12877)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fn3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_15"
                     /sec_met_domain="fn3 (E-value: 9.4e-11, bitscore: 35.0,
                     seeds: 98, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDILNFIIILSMSLLLASCGDDKDGINQPDPITGLTTEVFEESI
                     SLSWDVPNGEVKKYVIVYNPGDGLIDIVDPAITKYSIEKLKPGTDYEIDLYWVNNANVR
                     SLASTVNVTIPQKEGVIEHIYVGDLLLPNQKAIDNLQLKYTSVTGKLRIGNGTSGSDIT
                     DVSMLANITEVGTNLEVDGNSLLGNLDFLKNLKKIGGNFWLRNNPMLTSITGLKNLSEI
                     KTNLYIMGNPSLTNLNGLEGLTAVKLINIGIRSGNKSDKGNEKLTDLSALKPILTSLPT
                     VSYHCEGNAYNPSVDDILNDRGSDSK"
ORIGIN
        1 cgcagtacaa cggttttcaa gaccgccgca atcgaccact ctgccacctc tccaaaactt
       61 ctttatcaga agtgcttttc gttaaaagcg gtgcaaaggt acgaatatat tttaaactta
      121 caagagtttt cacaaaaaaa aatcacgaac atcatttcca aagaatagca atatctaggt
      181 attttatgtt gaaaagcata aaatagagca tatttatgct gattatatga aaaaacgttg
      241 taactttgtg cgctctaaag aaaaggataa ctacaacctc taattttatc atttatggaa
      301 ttaaataaga tctttaaaga cggtctttgg agcactgaaa tcaatgtcag agatttcgta
      361 agtcataaca tcactccgta ttacggagat gcttctttcc tcgaaggacc taccgaacgc
      421 acaaaagctg tatggaaccg ctgcctcgaa gcactggcag aagaaagagc caataacgga
      481 gtacgctcac tggataatgt caccgtctca accatcactt ctcataaagc cggatatatc
      541 gacaaagaaa acgaactgat cgtcggtctg cagacagacg aacttctgaa acgtgccatc
      601 aagcctttcg gaggtatcaa tgtggtaagc aaagcctgcc acgaaaacgg cgtggaagtg
      661 gacgaccgcg taaaagatat attcactcac taccgcaaga cgcacaacga cggagtattt
      721 gacgtatata ccgaagaaat ccgttcgttc cgttctctgg gattcctcac cggacttcct
      781 gacaactatg cccgcggacg tatcatcggc gactaccgcc gtatggctct ctatggtatc
      841 gaccgattga ttgaggcaaa aaaagaagat ttgcgtaacc ttaccggtcc gatgaccgaa
      901 gcccgcatcc gcctgcgcga agaagtggca gagcaaatca aggcattgaa ggacatgaag
      961 gtaatgggcg aatactacgg actcgacttg agccgtcctg cctacaccgc acaagaagca
     1021 gtacaatggg tatacatggc ttaccttgct gccgtaaaag aacaagacgg tgctgccatg
     1081 tcactgggta acgtctcttc gttcctcgac atttatatgg aatatgaatt gagcaaagga
     1141 accatcacag aatctttcgc acaggagctg atcgaccaat ttgtcatcaa actgcgtatg
     1201 gtgcgccacc tgcgtatgca atcttacaac gacatctttg ccggcgaccc gacatgggta
     1261 accgaatccc tgggcggacg cctcaacgac ggacgcacga aggtgacaaa gacttctttc
     1321 cgcttcctgc aaacactcta caacctcggc ccttcaccgg aaccgaacct gactgtattg
     1381 tggagcccgg aacttccgga aggattcaaa gaattctgcg caaaagtatc tatcgacact
     1441 tcttccatcc aatatgaaaa cgacgacctg atgcgtgaag tacgccagtc tgacgactac
     1501 ggaatcgcat gctgcgtatc ttatcaggaa atcggaaaac aaatccaatt cttcggcgca
     1561 cgttgcaacc tggcaaaagc cctgctgctt gccatcaacg gcggacgttg cgaaaacacc
     1621 ggtacggtaa tggtgaaaaa tatccccgta ctaaccagcg acacactgaa cttcgaagaa
     1681 gtaatgagca actacaagaa ggtattgaca gaaatcgccc gtgtttacaa cgaagcgatg
     1741 aacatcatcc attatatgca tgataagtat tactacgaaa aagcccaaat ggctcttgta
     1801 gataccaacc cacgcatcaa ccttgcttat ggtgtagccg gactttctat cgccctcgat
     1861 tcactgtcgg ccatcaaata tgccaaagta actgcacgcc gcaacgacat cggtctgaca
     1921 gaaggtttcg atattcaagg cgaattccct tgcttcggta atgacaacga caaggtagac
     1981 cacctgggtg ttgacctggt ctatttcttc agcgaagaat tgaagaaact tccggtttac
     2041 aaaaatgccc gtcctacttt atctttgctc accatcactt ccaacgtgat gtatggcaag
     2101 aagacaggtg ctactcccga cggacgcgcc aaaggtgtcg cttttgctcc gggagccaac
     2161 cctatgcacg gacgtgacaa gaacggtgcc atcgcctctt tgagttccgt agcgaaatta
     2221 cgttaccgcg actcacagga cggtatcagc aacactttct ccatcgtccc caaatcactg
     2281 ggagctactg aagaggatcg cgtagaaaat ctggtgacaa tgatggatgg ctatttcacc
     2341 aaaggcgctc accacctgaa cgtgaacgta ctgaaccgtg aaatgcttta cgatgccatg
     2401 gaacatccgg aaaaatatcc gcaactcacc atccgtgttt ccggttatgc cgtaaacttc
     2461 gtgaagttga gccgcgaaca tcaattggaa gttatcagcc gtagcttcca cgaacgtatg
     2521 taatcagatc tactcaatat gacgataaac gtacattcat acgaaagtat gggaacattc
     2581 gacgggccgg gcttacggct cgtcgttttt cttcaaggat gcaatttccg ctgcctgtat
     2641 tgcgccaacc ctgacacaat agccgggaaa ggaggcacac ctactccacc ggaagaaatc
     2701 gtccgcatgg ctatgagcca acgtcctttt ttcgggaaac gcggaggagt cactttctcc
     2761 ggaggagaac ctacgtttca ggccaaagca ctagtccctt tagtgcgtga actgaaagaa
     2821 aagggaatac atgtatgcat agacagcaac ggcggtatct ggaacgaaga agttgaagaa
     2881 cttttcaaac tgacggatct tgtattgctg gatattaaag agttcaatcc ggcacgccat
     2941 caagcactga ccggaagaag taacgagcaa accatccgca cggcagcatg gctggaagaa
     3001 aacgagaaac ctttctggct gcgttatgta ttagtgcccg gatacagcga tttcgaggaa
     3061 gacatccgcc gtttaggaga agctctggga aaatataaga tggtgcaacg agtggaaatc
     3121 ctgccttatc atacattagg cgtacataag tatgaagcga tggagcagga atacaagctg
     3181 aaagacgtaa aagaaaatac ccccgaacaa cttgaaaaag ctgcggaggt atttaaagag
     3241 tatttcacta ctgtggtggt caattaacca ccacagtaat aaataggata aaaatcacca
     3301 tgtctctgct ttcacctcga aacagggaca ctctttgatc cgctcccaag ggtcaacaat
     3361 tccattataa ttggtgtcag gactcaaatc acggtgtccc accacttttg catccggata
     3421 acgctgcaac agttcgcgca ccaggcgatg caaagattct ttctggcggg aagtacgcgt
     3481 atccgctgcc tttccgtcct catccagtcc gccttcataa cacaccccta aactaatcgc
     3541 attaaaaccg cgtgcatgag cacccaccgt atcttcatcc ctcatcggct ctatctgtcc
     3601 cgacttgcga atgtagtaat gataccccca acacgaaaag ccccgaaagc gatgggcagt
     3661 gtccacatcc ttcgccgtga agtcgcgatc agcacgggta gcagagcagt gaatcacaat
     3721 cagactaatc tttctcatcg tccttctccc tttccgtcgt tttcacatta cacacttcct
     3781 tatgggtagc attgaagcgc acctctctca caattctgtt ccgctttctt tttccgaaga
     3841 aaggcacaag gaacataatt acatccaaaa tcttagttac aatttctttc atttgatcca
     3901 atattaaagt tatcatgctg ccggatccgg agcttctccg cttccaccac cgtctgaacc
     3961 accaccggaa cctttgtcat cgtcttctcc ttcattgccg ctaccgcccg tttgagccac
     4021 cgcacgcgtc gttacctgct ggtagctaag aatcttcgtg atgtccgcca acgtctttcc
     4081 gggacggaaa ataatatggg cagccgtaat cagcgaactt gaaaactcct tgaccgacac
     4141 agctccttca ctgttcaacc cgatctgcaa actgcccaaa tcacccagcc ggactattct
     4201 tcccgctttc aacgcacgct tcgcctcata aagaataccc gaaatggcgg cacgcacatc
     4261 tgtctccgta caggtagacc gactggtgat tccttcgcac aactcttcaa aatccaactc
     4321 tcccgaagcc tgtgcctgcg cgtaatactt tgccgactca tcctttttgg caggattctt
     4381 gcgcggcact actgaataag ttactgtcat tgccataata aaataatttt aagatttcac
     4441 acatttcgaa cgcgttcctt atttgttaac gacataaaga taacacattt tccatcctcc
     4501 ggattcccca acgaagtttc ctgatactct atgaataata atgacgttat tcttttaata
     4561 aaccattaat tttcagtaac tttatagcat aaaccaaaca ttattcatca tgtattatcc
     4621 ggaccagccg tttcatatcc gcacttataa aaagtcggaa ctagctcatc tttacaaccc
     4681 caacgtatgc cttaaagtag ccttacaaat actacgtcgt tggattgtct acaaccctcc
     4741 gctcctgcaa gaactcgaac aagaaggcta tcgtgcccgc aaccgccttc tctctccccg
     4801 gcaagtggca acgatcatac gctatttggg agaaccctag gaacttaatc aaaaaaacga
     4861 aaagttccat tctattattt tacaaacaaa tttctttgca accgcaaatt aaaaagaaca
     4921 aaccaacatg gatcatttta ccatctttca agacttttac cgcgttatag ccgaaatgac
     4981 agaagaagaa atcgtatcgg ccatcagcaa cggcacatac cgggaaacgg tggaggacgt
     5041 gcgccgaatc ttcgcggaac aaggcgagaa agcagccaac gaaaagaaaa tagaactacc
     5101 agaaatcacc ttttcagcca actaccgggg aggacgttca aacgcaactc tcgtcaagta
     5161 tctgggatac atcgtggtag acatcgacca tcagacacag gaagcattgg cacgcatcct
     5221 cgcactggca aaaaagtgtg cccacacccg catcgctttc atcagcccca aaggaatggg
     5281 actgaaaatc gtggtacgtg tatgccggac agacgggaca ttgcccgaaa caattcagga
     5341 aattgaagat ttccatcatg ctgcttatca caaaatcgct tccttttatg cccagctctg
     5401 cggagttgag gtcgacactt ccgggcagga tgttagccgc acttgcctgt tctcttacga
     5461 tccggatatt tatttcaatc ccgatgccac agctgtcatc gtggaacagc caccgatgtt
     5521 cttcaagtct caaaagaaga aaagggcatc cggcaaaaag aaaaagacga cagcaccaga
     5581 caacaatccc ctcaccgaac aagtggccct caactaccat tcctcgcaca cttccttaat
     5641 ggtgactctg aactattatc acaataaatc cgaaaagtac gtcaccggca accggaacaa
     5701 ctacctgcat tgcctggctt gtatgtacaa tcgctacggc gtcccccagg aagaggcggc
     5761 agcttttatc aagagccagt tcaccgatct tcccgcggat gaaatggacg cactgatcgg
     5821 gagtgcttac ggacacaacg aggaattcga cacccgcaag ctgaatagta cgcagaagcg
     5881 aatgttacag attgagcaac atatcaaaga aaattacgat acacgctaca acgaagtgct
     5941 tcatatcatg gaatatcgca gaaggaaaac ggacacggag caaccggaac ctttccatat
     6001 tctcgacgaa atgatggaaa acagcatttg gatggagatg aacgaactgg gctattcgtg
     6061 caccgtcaag acgattcaga atctgatcta ctccgacttc agcatcacct accatcctat
     6121 tcgcgagtat ttagactcgc tgcctgaatg ggacggaacg gattatatcg gtatccttgc
     6181 caacagcgtg catactagtc accagaaatt ttgggtagaa tgtctggaac gttatctggt
     6241 gggaatgtgc gctgccgcca cacaagatga tgtggtgaac cacactgttt tgttgctttg
     6301 cagcgaaata cagaacatcg gaaagactac gtttatcaac aacctgctgc cgcccgaatt
     6361 gcgcgcctat ctttctaccg gtcttatcaa cccgagcaac aaagatgatc tggctaaaat
     6421 agcgcaggcg atgcttatca atctggatga gtttgaaggg atgagcggac gggaactgaa
     6481 tatcttcaag gatttagtca cccgcaaagt aatcagcatc cgcctgccat acgcgcggcg
     6541 ttcgcagaac tttcctcata cggcttcttt tgccggcaca tgcaattacc aggaagtgct
     6601 tcacgacacc acaggtaacc gccgttttct ctgctttcat gtcgactcga tggagtttat
     6661 caaaataaac tacgcgcagt tgtatgcaca aatcaagtat ctactcaaca agccggggta
     6721 tcagtattgg ttcacccagt cggaaaactc acggattgaa gagaacaacg aggatttcat
     6781 tttccactca ccggaagaag aactggtgtt gacacatatc cgcaaaccgg aacgtttcga
     6841 aaaggtgcat tatctgacgg tcactgaaat tgcggaattg attcgcgaac ggacggggta
     6901 tcaatattct cacggaacca aagcccaact aggaaaagtg atgtccaaac acggcttcga
     6961 atttcataag ggaaaaaacg ggagaagata cactgtattc attattgata cggaacaggt
     7021 gaaatcaaac aggctatatg aataagattt catctccttc gcacgcaaaa aggtgagggt
     7081 tggtgagggt acttttgcaa cttttcattt ttatatttct tatttctatt cttctatttt
     7141 cttctaaaaa aaaatacgaa tgttagaaat ttaccctcac ctaccctcac ctttttcctt
     7201 tttcttcctc tttcttcctc aaaaaaacgg tgggaaattt gaaaaagaca gttaactttt
     7261 tcaaatttcc caccatgttt ttttaatcgc ttcttataaa gacatcgaaa attcgatcct
     7321 acaacctaac gcattcatga tgcgatagaa ggtagaaacc ttaggctctg tctgaccact
     7381 ttccactctt gaaatataag aacggtcgga accgatacgt cgggctaact ctgcttgagt
     7441 aatcttagcc tttttccttg cgtcttcgat aatttgcccg gtgtagaaag catacgcttt
     7501 ttcttctgct tccgcacgag taacagttcc ttccttacca aaacgctcat ctattaatgc
     7561 gctgacgtta aagaattcct catttgtttt tgcttccata atactccttt cttaatatct
     7621 ttgctttttc aatttctttc tttggggtct tttctgtttt cttttggaat ccgttaaaga
     7681 gtatcacaat acgtccttca tcgaaacaaa agaatattct atatatatta ctctggtact
     7741 caatacgaag ttcataaagt ccttcttcta tcaacttcat aaacttcaaa ggtattctgt
     7801 cctgcgtttg caatagcatt aacacatata atatcttatc ttgggtgcca gtatccagac
     7861 gatcaaagaa ctctttgaaa tatcctttat atgctattat ttctcttttc atactgcaaa
     7921 tatatgaatt gttgttcaac tatacaacat tcgtcttttt attttatatt atttttcctc
     7981 aaattctccg gcacgctttt tcttctcata agacaccagc gtctctacac taagcgtttt
     8041 cccattctta gggcttatca catctacaac gcttgctaac gcacgaaaag tctgttcgca
     8101 atttgctatt ccgtcatacg tcaacctacc ccgattgatg gcatcgagca caacagagac
     8161 atattgcttc ggatttcccc gatactcaat ggtgacaggc gtgagatgcg acatctctcg
     8221 agtcagttga ctgacgattc ttttttttgg tcgagcagct ccattaattt ttcactatgc
     8281 acattgattt gtgcggttac ttcacgaagt tcatttttca atgaacaaaa caattcatca
     8341 ttacatgaat tttccataaa acttttcatt taattgatta taaaaaagcc attccggaaa
     8401 gataagcaat cattacttac ttcccggaat ggtgactaac atttttaaga ccagtttttg
     8461 tatattactg tttctttcaa tggacaaaag tagccaattt attcctataa tatctttcca
     8521 cctcttccca atgataatag ggtactagct cacttgcaag cggaagtttc atttcttgtt
     8581 cattgagtaa aattttcacc aagatattat catttccttt cttacggtaa aaaacgaact
     8641 gaatattaca agcttttgga aagatacgat agttacgcca tatatctgac aatttattta
     8701 tatcagtagt ctgatatgca caatcaccta attccaataa acaagccaaa ggaagtagac
     8761 aagtctcgtg cccgaagcgc agggtagcac tattctcttt tttcacgacg caagtatctg
     8821 cagtattcag tatattctca agcaggtttg cttccacata aggcatctta ccttgagtga
     8881 gcggagacgg cccgtagtca atataccaat tcagattgct gattagccat aaatcataac
     8941 actcttcttt ggtaaaaaga gaataaagat caaggtccgt gtcgtgactt tgcgtaatgg
     9001 ctgccagttc aaacaaataa ctcatcaact tgccagcatc cactttccac tttacataat
     9061 tatcgttatt aaaaagagac ttcatcaaac gttcgggatg gagatgctct ttccgaaaag
     9121 ctgcctttac agcaatcact tcatcttcct gacgcttctt tttgaagtat tcatttccat
     9181 aattcatata atacatatca taagaagtag cctcatcctt gattctcaac tccggattca
     9241 gagattgcaa ttgcaagcac tcagccgtca tagagagtat acagcggata acggttgtag
     9301 aacgtgcatc cacctctgcc gctccctgaa acacttcagg aaagttattg tacattcttc
     9361 gggcaattcc cctgtgttga cgggcaccta atggagtcaa atcaccatat ctattttctg
     9421 ctccgcgcgc aaggctgtct acaagccaga gggccttctt gcctaaatct gtaagtactc
     9481 cgtctttctc tgcttcgcga agaattgcca acggcttcgt ataatcatca ggattcactc
     9541 tataacggga accgtgacga gcataatggc ttaggtagaa cggtttatac cccttgggtg
     9601 gggcagtcat tgtgaaatgg ggatcaggat aggcataatg gttggctgcc gagcgatgta
     9661 tgtcttcaaa tatttcatct cttgctatct gtgcacttat actaagcaca aggcaacaaa
     9721 ggattgtcaa caaaataaaa cgtttcatac tttctttttt taataagttt aagataccac
     9781 agaattattc actagagtaa ggaccaaacc tgttcgatat aaccaagtct gttttccggg
     9841 catccagcac atatacttca tattccccgt ctggatatac tcttatcaca atgtgcccct
     9901 gttttgcttt caagctacgg gcaaaccaag gaccaatagc tacccccgtt tcatcatcat
     9961 agtaagtcat aaaaacatcc ctaggctgcg ttccgatatt ctttgataac aaccgttgcc
    10021 ccacttccgc tcccggatga tcggtactcc atgattgagc cactactact ttaggatcga
    10081 gcacttcgag aaagttccgg ttagtggcat cccgattgct atgatgattg agcgacactg
    10141 ccgacacctt tcctattatg ggtgccatag gagtttctat atcataccat tccgcatggt
    10201 cttggtctac caaaccagaa ttatcccctc ccgcataata cttgaatgcg ccatatttca
    10261 ccacaatagc cgtcgacatt tggttttcac tatacttgcc attttttgcc atcaattctt
    10321 ccttggtaaa cagaatagtc gtttttttac cttcccctgt ccacaaccga ttattcgatt
    10381 ttatattcct gacttcaaac cccggataag atttcggttc tttctttaat acaaattgcg
    10441 tattagagcc tatgtcgaac ttttcgactt tcaatccgtt gtgtttttcc tgatagttga
    10501 ggaactccaa taggttcaag aaagtaggca aatctactcc atcattcttt gatcgtaaat
    10561 ccacggggaa ttggtagtca ggataatccc tatcaacata cattttgata ggaatcacat
    10621 ctccgacttc cgtcagcccc gtaatacgat atccgttttt ggaagttcca gtggccttct
    10681 gaacatcacc ataatgatcg gaatgaaaat gggtcagaag aaaatagtca atcactacat
    10741 cctttcccaa tagatttgtc acataattaa tgatagacga accgggcgta taactactat
    10801 ccggaaatat cggagctgca tgcatcggtg catacttagc ggcatattcc ttgccatcaa
    10861 aatcaccggc atcaatcatc atggtcgttc cgtcaggaaa aatcagaaaa gcgcaattcc
    10921 cccgcccggt attgatgtga tgaatatcaa ggtatccttt ctcccattta gggaaaggcg
    10981 gtattgtcat ttgagccttg attatacaac taaaaacgag taaaaatatg aaattaacta
    11041 ttttctttat atccatcgtt ctatcaatct gtttataaat tactactgta ctttattctc
    11101 caataattat tttactccat agaaatggat gatctgaaag actaatgtct tttttaaaaa
    11161 tgctatatgc gatttccgct ttcataccag aattcttatt gattaatata ttatcaatct
    11221 gcccatattt gtatttatca atatattgtt cagcatcttc cacatcatcc catacactct
    11281 taaagcctga attaaagatg tattgcatgg cattagtttc cggcaaatca ttgaagtcgc
    11341 ccatgactat gattctttta ctagtatctt tcatcaaaac aacatctact aaattcttca
    11401 tgacagaacc ttcaactact cctgcgctac ccggaatatg cagactataa aaggttagtt
    11461 ccttattttt aatcttggtt tcaatccgaa tagtcgatga atgtgtccaa ccttttccct
    11521 ccaaagcaaa ttcttttgac tgcaatatag gagttttact caatattact ttgtattttc
    11581 ctgcatattt tccagtttta tcctttcccc attcaatcca atgatttccg gaggatatat
    11641 caccgatata aaaatattcc attcccaaag ctttacctat tattgaataa aactcttcaa
    11701 ctccggaatt cttatcaatc aaaatgggac attcttccaa tgaaagaata tctaaataaa
    11761 aagactttag actcaatgct atttcttccg ctgtcgccgt ttgccctaca tccacgttaa
    11821 aagttccgac acgaatagaa gtatctatta taggggggat tttttcctta tcattctccg
    11881 gagtatcact actgcatgag aatataaaag gcaatattat aagcaaaata ttcagatatt
    11941 tcatagctat taattattta gaatcagacc ctctatcatt taagatatca tctactgatg
    12001 gattgtaggc attaccttca caatgataac ttactgtagg cagactggtt aatattggtt
    12061 ttaatgcgga aaggtcagtt aatttttcat tacctttgtc tgatttgttt ccacttctta
    12121 tccctatatt aattagtttc actgccgtaa gcccttctaa tccattcaag tttgtaaggc
    12181 tgggatttcc cataatataa agattcgtct ttatttcact taaatttttc agaccggtta
    12241 ttgaagtcaa cattggatta tttctcaacc aaaaattacc gccaatcttc tttagatttt
    12301 ttagaaaatc aagatttccc agaagactat taccatctac ctcaaggttt gtacccacct
    12361 cggtaatgtt tgcaagcata gatacatctg taatatcact gcctgatgtc ccatttccaa
    12421 ttcgtaattt accggtcaca gaagtgtatt tcaactgtaa attatcgatt gccttttgat
    12481 ttggcagcag caaatcgcct acataaatat gttctatcac tccttctttc tgtggaatcg
    12541 ttacattaac cgtacttgca agagaacgta catttgcatt attcacccaa tacaaatcaa
    12601 tctcgtagtc cgtgcccggt ttcaactttt caattgaata tttagttata gcaggatcaa
    12661 cgatatcaat cagtccgtct ccgggattat atacaatgac atacttcttt acttccccgt
    12721 ttggtacatc ccatgataaa gaaatacttt cttcaaatac ctccgttgtc aaccctgtta
    12781 tcggatctgg ttgatttatc ccgtctttat catctccaca tgaggctaac aataaggaca
    12841 tcgataaaat aatgatgaag tttaaaatat ctttcatgac tctattttta ttttttatat
    12901 taatattccg gattttgttt aataacgaca ggatttgcat taatctcgcg ttgcggtata
    12961 ggatatacta attgataatc tttcaccgtg aacttactgc tctcctggct gctattattc
    13021 attgtttcga cagcagtacc tgtacgaatc aaatcgaacc acctatggtt ttcaaaagcg
    13081 agttccaatc ttctttcatc cgcaatggct tttctgaaac ttgtttgatc cggcaaatcg
    13141 tctgaatcat aagtagatac tcctgcgcgc gaacgtatac tgttcagaag cgtaaaggcc
    13201 tcacctgaat cgtcacccgt atatcctatt tcatttaaag cttctgccag cataagaact
    13261 acatccg
//
