LOCUS       c00001_gnlPro..        13704 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PPILAPIJ_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:03:59
            Original ID  :: gnl|Prokka|PPILAPIJ_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13704
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13704
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[214:3704]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      215..3704
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13704
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13704
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(215..982)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1"
                     /sec_met_domain="Fer2_3 (E-value: 1.3e-22, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.4e-10, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIASGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1023..2981)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.5e-53, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.9e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3003..3704)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3"
                     /sec_met_domain="SucD_FumR (E-value: 1.5e-12, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3905..4177
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAATRAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4210..4995
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5029..5262)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5694..6401)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MNKLLSTLILSVGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSTTYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             6636..7703
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MREKISATDHAALAILKKTGLDVVEAAQLAHELLQASKGRGSRWK
                     RARECIRLGEEALVARGKTVAFRKAVQEAMEARQDRRKRTRDDFRYISRRLLRFCPEMA
                     RRPVRFITPRECRACLEKSFDTLRQRHKARLVLSGIFGTAVKRGWCTENPVAHVDLPRL
                     KEHSIPVLSLEEMRRLLAAAEEYDGGACLAAVGLMLYAGIRPEEVRRLDWAQINLREGM
                     VSLRARHSKTGGARIVTIQPVLGNLLERAVAMGSVSGSVCPRNWPAKWRELRRLAGWDG
                     KEKKWPADMLRHTFASYFARHFKNLHVLQMEMGHASSDLLRTRYLNMEGITEMTAAVFW
                     GNCHAGRHAIKNGRP"
     CDS             complement(7746..9077)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MKTYTLPVIGLMTLGASAFAAAAPSTGNSLPARDNFSACKWLGDR
                     FKWFNSERDHKNPYIQEFNVSLRMQYGLDWIDPNGEGRVMGEKEGNGRRFNDEWRRFRA
                     GFNMKFLNNFKLNNVWNIGGMDGLESYNAKTNTWDTSDLTYSLYELNLEYKGGPVTYAI
                     GKIKPRITGEYRTSSSAILTIERSMLVNQLRSETNYGFQVNNSDKKDKLGWAAGVWLNG
                     NGGTGTGTFNNRIEPAFNSRDNCFITGTLSYDTSNDVFLKKSRLWLDYAHNFTKWGDDA
                     QNKAYEKLTGYGFKSKYQGTGARDVVALTWEGSEGDFSLMTEVMAGFNVIGMKAGAENV
                     FGVTVMPSYKFTPHWEGVVRYQMAAGSNAVKWEKRYTQNSTYSGTSDCMQALYLGVNYY
                     IFECSPNMAKIMAGIEYAHSNGTDASRQKGFTGWSYNIAFRTNF"
     CDS             complement(9221..10030)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MSKLGDGRDDAGKQIPSPPGSSLRLELHFRNGGPSISGMNHTALE
                     DKLGYRFNNPDLLVQALTHPSTDSKPETRRAYERLEFLGDAILQLAVTQYLYHHMPQSP
                     EGELTQLRARTVSRANLGKYGFILGLDKHIALGKGEERAGGRSKNSIIANTFESVFGAM
                     SLDSNYETAKAVALRVLHEALDSAASHPKEINPKGELQAILQDILPETPSYETEEKGPR
                     DAENRFESRVFWHGHAIGAGSGASKRKAEVAAAADALDARAWLRMTL"
     CDS             10080..10583
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MKKIEPKEIQDNAVQLIGDDWMLVTAGSPEHFNMMTASWGGLGFM
                     WKKPVAFVVIRPQRHTFRFIEAGDELTLSFFSHEYHKALTVCGTTSGRDTDKVAASGLT
                     PYVTENGNVSFTEARLVLECRKLYAEPLNPEAFLDKSIVPEWYAAGDFHKMYIVEILNV
                     WVKE"
     CDS             complement(10638..11693)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MISRLKLMDFRCYGSFSWQIPQQGAIILGNNARGKTSLLEAVCFL
                     LRLQSPRTARTGPLVSHGKQSFGIRGELPGQIRRILWAPDAPDLRVNGEPRKDQRSYLA
                     DSYPVVWMGNDDLSLVQAGADTRRKYMDFLGSQWHPGYRLALFSYRRALKTRNYLLKHR
                     HRDKLQLDAYTRQLALHGTELRNLRAHLLALLAPHIALAYRNIGGRQEQVSIAYRASEE
                     GDLYERLCASMDRDIRYGQTQNGPHRDDLDITLNGRNAAQFASEGQQRTTAISMKLAQS
                     SLLTEETGHTPIHLIDDVFGELDPTRRIAFLQSLPADAQSLITTTHLDWLHDAPCPLPA
                     FRLEDGTLAPL"
     CDS             complement(11711..12322)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_13"
                     /sec_met_domain="Acyltransferase (E-value: 1.6e-23,
                     bitscore: 77.3, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSFYWVFYTLFKSISKAFFSWKVVNREKLIEDGPVLIVSNHQSF
                     LDPPMLGISYEDGIYFFARKTLFQGIFKWALPLCQAIPIDQENPDAASLKHVIRLLKSG
                     KRVLVFPEGSRTPDGKIHDGMGGIGLILSKTKVPVQPLRISGAYEAFPIGARFPRLRPV
                     TVTVGDPIPFTPAELNAKGKDAYQHLTDKIMDAIRSLPAE"
     CDS             complement(12319..12960)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_14"
                     /sec_met_domain="Cytidylate_kin (E-value: 1.6e-68,
                     bitscore: 225.1, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPAIAIDGPAASGKSTVAKLIADRLGYTFINTGAMYRAVTWYML
                     EQGINPADTAAVLESLPSVPLSFGKDGSQSVVLCGQHVLGEELTSQQVNDHVSTIAAIP
                     EVRALLVERQREYNRREPVVMEGRDIGTVVFPDTPFKYFVTASEEVRAARRAAEGLTDS
                     IAERDRKDSSRATAPLAQAPDALLVDTSDMTIDQVVRFITDNIQQKLSSR"
ORIGIN
        1 gggcctgctt aggtttcgtc cggcatttcc aagtacggtc tcctggatta ctgggaacct
       61 tccggtgtaa catttatttt ttacgctgcg cgacgatgag gaagcaactg tctgatattt
      121 tattcctggt tcaaggaaac ctgataatga aaaaaactcc cgacagccga tgccgccggg
      181 agtttttaca gagcgtctta agaaggaatc ttctttagaa acagagacct tccttggcgt
      241 tggctcgcat gaagtcgcgg ttgaggcggg cgatgttgtc cacgctgatg cctttcgggc
      301 aggcagcttc acattcatac tggttcgtgc agttgccgaa gccttccgct tccatttgct
      361 tcatcatggc caggacgcgc ttggaacgtt ccggctggcc ctgcggcagc agattgagat
      421 gggcgatctt ggcggaggtg aacagcatgg cggaggcgtt tttacaggag gccacgcagg
      481 cgccgcagcc gatgcaggcg gccgcgtcaa aggcggcgtc cgccttcact ttttccacgg
      541 cgatgttgtt ggcgttcggc gcggaaccgg tacgcacgtc aatatagcct ccggaggcga
      601 tgatgcggtc cagggcggag cggtccacca tcaggtcccg caggattggg aaagccttcg
      661 cgcggaaggg ttcaatccag acggtatcgc cgtccttgaa cttgcgcatg tgaagctggc
      721 aagtggtcac ctggcgttcc ggcccgtggg gaatgccgtt gatggtcagg gagcacatgc
      781 cgcagatgcc ttcccggcag tcgtggtcaa aatggatggg ttccttgcct tccttgacca
      841 ggccttcatt gacgatgtcc agcatttcca ggaaggaggc gtccaccgga atgtccttgg
      901 cggcataggt ctcaatgcgg cccttagctt cccggttttc ctggcgccag accttgagag
      961 tgagattgag tgttttagcc atgttataat ctttcttttg agtgttaatg tattggctat
     1021 ctttacttgt agctgcggat ggcaaggtgc acgttctcga aggtcagcgg ttccttgtgg
     1081 agaacaggca ggctgtccac gccagtgtat tcccaggcgg ctacataggc gtattcatcg
     1141 tcgttgcgct tggcttcgcc gtccggcagc tggtattcca cgcggaagtg ggcgccgcag
     1201 gattcctggc ggttcagggc gtcatagcag agcagctggg cgaattccag gaagtcggcc
     1261 acgcggcagg ctttttccag ttccgcgttg atgccgtccg ccgtgccggt tacgcgcacg
     1321 ttttcccaga attccttgcg gagctgggga atgcgttcaa tggcgtgggt caggctttct
     1381 tccgtgcggg ccatgccgca gtcttcccac atgatgaggc ccagttcccg gtggaaggag
     1441 tccaccgtct tggtgccctt cacattcagg agcttgttga tgcgttcctt cacttcgtct
     1501 tccgcagcct tgaattccgg ggcggcggtg gtgacggcac cgggcttggt ggtcgtcagg
     1561 taagcgggca gcgtggcggg aatgacgaag tagccgtcag acaggccctg catcagggcg
     1621 gaggctccca ggcggttggc gccgtgatcg gagaagttgg cttcaccgag gacgtgcaac
     1681 cccttcacgt tggacatgag gttgtagtcc acccacaggc cgcccatggt gtagtgggag
     1741 gcggggtaga tcatcatggg cgtttcatgg gggtcgtcgt ccgtgatttc ttcgtacatg
     1801 tcaaacagat tgccgtattg gccgtcaatc cattcgcggc ccatgcgctt gatttcatcc
     1861 gcaaaatcca ggaagacgcc cttgccggtg acggccacgc cgcggccgtc gtcgcaggct
     1921 tccttggcgg cgcgggagga aatgtcgcgc ggagccaggt tgccgaagga gggatacttg
     1981 cgttccaggt agtagtcccg ttcttcttcg ggaacatcgg aaggcttgat ttccttctta
     2041 cggatttttt ctgcggtttc acgggacttg ggcacccaga tgcggccgct gttgcggagg
     2101 gattccgaca tcagcgtcag tttggactgg tagtcgcctt tgaccggaat gcaggtgggg
     2161 tggatttgcg tgaagcaggg gttggcgaag aaggcaccac gcttgtaggc tttgtaggcg
     2221 gcagtgacgt tgcaacccat cgcgttggtg gacaggaaga acacgttgcc gtagccgccc
     2281 gtgcagagca ggacggtatc ccctgcgtag gatttgattt cgccggtaac cagattgcgg
     2341 gtgacgatgc ccttggcttc gccgtccacc aacaccaggt ccatcatttc atggcgggag
     2401 aacatttcaa tgtgtccctt ggccacttcc ttttccaggg cctggtaggc acccagcagg
     2461 agctgctggc ccgtctgtcc gcgtgcgtag aaggttcgct tgagctgggc gccgccgaag
     2521 gagcggttgt ccagcaggcc gccgtattca cggccgaagg gaacgccctg ggccacacac
     2581 tggtcaatga tgttggagga gacttccgcc agacggtaga cattggcttc acgggcgcgg
     2641 aagtcgccgc ctttaacggt gtcgtaaaac aggcggtaaa cggagtcgcc gtcgttctgg
     2701 tagttcttgg ccgcgttaat gccgccctgg gccgcaatgg agtgggcgcg gcgggggctg
     2761 tcctggtagc agaagcattt gacgttgtag ccaagttcgg caagcgtggc ggcagcggag
     2821 gcgccagcca ggccggaacc taccacaagt accgtgtact tgcgcttgtt gttcggattg
     2881 atcagtttgg actcaagttt gtacttggac catttgtcct gaatagggcc ggagggaatt
     2941 ttggcatccg gcatccagtc gcttacggga aaattaatca tgactttgag aggagttgat
     3001 ggttatttga tgatacccag aagaaccgag accggcacgg agatgaagcc caggcagata
     3061 atcgcgccgt aggcgatggc gataaagttg tagaagggcc ggattttgcg ggaatcgacg
     3121 cccacagtct ggaagatgga ctgtaccccg tggcgcagat ggctgaacag catcagaacg
     3181 gccaggatgt agaaggcgga gcaccatacg ttggagaatc cggtcacgat catcttgtac
     3241 acgtcaaagg tttccaccgt accgtcggaa ataaaggtgg tgaactgggc ggggtcgtat
     3301 cccacgcgca gggtgtactg gtacaggtgg tagatcagga acaccaggac ggtcaaaccg
     3361 gtgtaaatca tgtagcggga ggagagcgtt gccttaatgg tgttcttgaa cacgtagggt
     3421 tcgcgggccg catggttttc cagcttcagc tggatggtca gccagacgtg gatgatgaag
     3481 atcaccgcaa gccccgcgcg gattccccag agggctgctt ccggcatgga gtgcaggccg
     3541 tgggcgtagg tgttgatcca ttcagggcct ccgaagatga gaaggttgcc tgccaggtgt
     3601 cccgcaagga acaagaccaa acataacccc gtcagagcca caatgatttt gcggccgatg
     3661 gaggatgtca cgaatgtaca tatggttttt actagtgcat tcataggcgc tctaatgaaa
     3721 taaatgcgtc ttcacaggat gcccggttca agcccggatg gcaagcctct tcttgaattt
     3781 ccggcgcttt tcggattttt gaaaaaccgg ggaaagaggt tgctgtttat cagtttggaa
     3841 tggttatcat tttgttgcct gttccggctt gacgaggctt tccgcatagg cgtatcgtct
     3901 gtgcatgaaa agaagtaaaa aggaggtgct ggacgcggat ttcgcagcga cgcgcgccgg
     3961 cgttctggat gtggccgcat ttctggaccg ggtggaccgc ggggaagggg aggcggattt
     4021 ccgctaccat gccctgatgg atgttcttcc cctcttgtcc gcatccggcc ccggacgcgt
     4081 ccgggccatt ctggaagccc tttcctacag ggatgacacc gtgccggaaa ccgccgcagc
     4141 caaagcggcc tgcggagccc cgaacctcag caaataagaa tgatggcttt catagaacct
     4201 catatacata tggtgtgccg caccacggac gaataccggg ccatggcgca ggccggctgc
     4261 ctggcggtag gggaaccggc gttctgggcc ggttacgacc gttcgtccgc ggacggtttc
     4321 cgggattatt tcgtacagct tacggaatgc gaacccgcca gggcggccaa gttcggcatg
     4381 gaccattaca catggctgtg catcaatccc aaggaggcgc aggacgtggc tttcgcgcgg
     4441 gatgtgatga aactgattcc ggagttcatt gaccggccca atgtcctcgg catcggggaa
     4501 atagggctga accggaatac ttcccatgaa atgactattt ttgaagagca tctggatctg
     4561 gcggtgcgcc tcaaccagct tgtgctgatt cacactcccc atctggaaga caagcttaag
     4621 gggaccgtaa tgattctttc cgccctgaaa aaccgtccgg atctggaccc ttgccgcgtg
     4681 ctggtggatc actgtgagga acataccttc ccgctggtga aggaggccgg ttactgggcc
     4741 gggctgaccc tttatcccac cagtaagctg aatcccaagc gggcggcgga tattctggaa
     4801 ttgtacggaa tggaccgtgt ctgggccaat tccgcggcgg actgggggga ttccgatccc
     4861 ctggcgctga cggccctggc ctgcgagcta cgcaggcgcg gtttttcccg gcaggaaacg
     4921 gaacgtcttc tcctggaaaa tccggagaca ttcatgggac agtccccgaa gttccggaaa
     4981 gtgtcgtccc gctaattccg cccgaggcgc ggcggagggt acggccctct agtccccgtc
     5041 cgggaaaaag acggtgagga cggcgcccag gatgaccgcc gcgtcatcca gaaggcccag
     5101 cctgccgatt ccgtcaaaca ggaattcgtc gggagtcagg atgtaggcgc cggcggcggc
     5161 cagaaggcat atattccgtt tgttgaaaaa acgcggttct ccttttctgc ttttgaaata
     5221 ccggaacagg cgcagtagca gctgctgttt ttgaaggttc atggacggga acgggggata
     5281 aaggttcaag ctcagccatt ttcccactcc ttttccctgt ttcggggaag gagtctgttg
     5341 ccgacggacg gaaaccgcag cgatccggac cgtgcgggga aatggattgc tgaaaggatg
     5401 ggctgttccg gatgctgagg gaagccgggc tttgcatgct ccggttccgg ctgtcccggc
     5461 atgggaaaaa ggggcgtgta cggaagtggg gcggggccgg aagctcttga aatgaccctc
     5521 ccgggggagc ctgaatgcca tttccccgtc aagtgctggc cgtgagggta ccgcagcaaa
     5581 tggaagcttc ttcccccctg ttttttccgg cagatgtttg aacggataag gaaaaggccg
     5641 gctcacgatt ttgtgagccg gcctttgaat atagggaggc ggacggtaca ggcttatgcc
     5701 ctgcggcggc gcatcatcag cgcggccagt cccagcaggc ccagggaagc cgtggcgggt
     5761 tccgggatgc tggcgatttc actcatcagt tgaccaactt gttcctggga aaggagggag
     5821 tcgtgaatgt agagctgttc gatggattca gccagtcctg cgtccatgag aatctgatca
     5881 atttgctggt tgccgaattt caggccgctg ttggaatagt acgtagtgct gtctccaaaa
     5941 tagatgcggg tgccaagatc tccggtgact acggaaatgg tcagggaacc ttccgtgccc
     6001 agcggggtgt caacgacagg cccgctgtag gaggtgttgt tccataatcc ctggagtttc
     6061 cggtccgtgt tcaggcccac gccccagctt acactgctgt ttttggcgtt aaacagagcg
     6121 gtataggcgt ccggagtgtt gattttggac aggtcaagaa ccatcgtcac agacataacg
     6181 tcgcggttgt tggcaccgta tccgttgaag gttatcccgg ataacgtcag attgctgtcg
     6241 tcagacgtga tggaaacgga atctttcagg gtgccgaaat ccgccgtttg ggaggcaaag
     6301 tccgaatatc ccacgatgga gctatccagc agagaggtag ccgcggtagc gcttaggctc
     6361 atgccgaccg aaagaatcag ggtggataat aatttattca tggtcagtat cttaataaaa
     6421 tgatgcaaga ttcaatgtat gtacttgtgc ttgaataacg aatttggaat ccgtatagga
     6481 attcctgtgt cctctttgtc atcaaactgt ctggaagaga attgctgata tgacggtgcg
     6541 gtgaaacggc atgaatgaag ttggcgaacc ttttgattaa taaacgacta tttttacttg
     6601 actacggatt ccaaaaccgt tgcaaaatat atgaaatgag agagaaaatt tcagcaacgg
     6661 atcatgcggc gctggccatt ttaaaaaaga cagggctgga tgtggtggaa gccgcccagc
     6721 tggcgcatga attgctgcag gccagcaaag ggcgcggcag ccgatggaag agggcaaggg
     6781 aatgcatccg gctgggagag gaagccctgg ttgccagagg aaaaacggta gcgttcagga
     6841 aagctgtgca ggaggctatg gaggcccggc aagatcgcag gaaaagaacc agggatgatt
     6901 tccgttatat cagccggcgt ttgttgaggt tttgtccgga aatggcccgg aggcccgtgc
     6961 gctttatcac gccccgggaa tgccgcgcct gcctggaaaa atcatttgat accctcaggc
     7021 agaggcataa ggcccggttg gtgctcagtg gtattttcgg aacggccgtg aaacgcggct
     7081 ggtgcacgga aaacccggtg gcgcatgtgg acctgccgag gctgaaggag cattccattc
     7141 ccgtgctgtc cctggaagaa atgcgccggt tgctggcggc ggcggaagag tatgacggag
     7201 gggcgtgcct ggccgcggtt gggctgatgc tgtatgccgg catccgcccg gaagaagtga
     7261 gaaggctgga ttgggcacag attaatttaa gggagggaat ggtttccctg agggcgcgcc
     7321 acagcaagac gggaggagcc cgcattgtga cgatccagcc ggttttggga aatctgctgg
     7381 aaagagcggt tgctatggga tctgtgtcgg gaagcgtatg cccgcgcaac tggccggcga
     7441 agtggaggga gctgagacgg ttggccgggt gggacgggaa ggaaaagaag tggcctgcgg
     7501 atatgttaag gcatacgttt gccagttatt ttgccaggca tttcaagaat ttgcatgtat
     7561 tgcagatgga aatggggcat gcttcttccg atttgctaag aaccaggtat ttgaatatgg
     7621 aaggcattac ggaaatgacg gctgccgttt tttgggggaa ctgccatgca gggcgccacg
     7681 ccattaaaaa tggccgcccc tgaacagaag cggccagctg ttgacgggat gataccgtcc
     7741 ggcaattaga agttggtgcg gaaagcgata ttgtagctcc atccggtaaa gcctttctgc
     7801 cggctggcgt ccgtgccgtt ggaatgggcg tattcgatgc ccgccatgat cttggccatg
     7861 tttgggctgc attcgaaaat gtagtagttg acgcccaggt acagggcctg catgcagtcg
     7921 gaagttccgg aataagtgga gttctgcgta tagcgctttt cccattttac ggcgttgctg
     7981 cccgccgcca tctggtagcg gaccactcct tcccagtggg gggtgaactt gtaggacggc
     8041 atgacggtca cgccgaagac gttttcagcc cccgctttca tgccgatgac gttgaagccg
     8101 gccatgactt cggtcatcag ggagaagtcc ccctcggaac cttcccaggt cagggctacc
     8161 acgtccctgg ctccggtacc ctggtatttg gatttaaagc cgtaaccggt cagtttttca
     8221 tacgccttgt tttgggcgtc gtccccccac ttggtgaaat tgtgggcgta atccagccac
     8281 agacggcttt tcttcaggaa aacgtcgttg gacgtgtcat agctcagcgt gccggtgatg
     8341 aagcagttgt cccgggaatt gaaagcgggt tcaatgcggt tgttgaacgt gccggttccg
     8401 gtgcccccgt tgccgttcag ccagacgcct gctgcccagc cgagcttatc ctttttgtcg
     8461 gaattgttca cctggaatcc gtaattggtt tccgagcgga gctggttgac cagcatggag
     8521 cgttcgatag tcagaatggc ggaggaggat gttcggtatt ccccggtgat gcgcggcttt
     8581 attttgccga tggcataggt gacggggcct cccttgtatt ccagattcag ttcgtaaagg
     8641 gagtaggtca ggtcggaggt gtcccatgtg ttggtttttg cattgtagct ttccaggccg
     8701 tccatgccgc cgatgttcca gacgttgttg agcttgaagt tgttcagaaa cttcatgttg
     8761 aacccggcgc ggaagcggcg ccattcatcg ttgaagcggc ggccgttgcc ttccttttct
     8821 cccatgacgc ggccttcgcc gttcgggtca atccagtcca gtccgtactg catgcggagg
     8881 gaaacgttga attcctggat gtagggattc ttgtggtccc gttccgagtt gaaccacttg
     8941 aaacggtcgc cgagccattt gcaggcggaa aagttgtcgc gggccggcag ggagtttccg
     9001 gtagagggag cggcagcggc aaaggcggag gctccgagag tcatgaggcc gatgacgggg
     9061 agagtatagg tcttcatttg ttttctatgg ttggtttgtc tgtgagaagg tcttccgggg
     9121 aaggttcttc ctcacggaga cggcttctgt ctatcaaacc agccacagga gtgtccaagg
     9181 cttaagggtg acaaaatagc cacccgtccc cctttggcgg ttacaaggtc atgcggagcc
     9241 atgccctggc gtccagggcg tctgcggcgg cggccacttc cgcctttctc ttgctggccc
     9301 cggaaccggc tccaatggcg tgaccatgcc agaaaacgcg ggattcaaaa cggttttcgg
     9361 cgtctctcgg ccctttttct tccgtttcat aggaaggagt ttcgggcagg atgtcctgaa
     9421 ggatagcctg gagttccccc ttggggttga tttccttggg atggctggcc gcggaatcca
     9481 gagcttcatg gaggacgcgc agggccacag ccttggccgt ttcatagttg gaatccaggg
     9541 acatggctcc gaagacggat tcaaatgtgt tggcgatgat ggaatttttg ctccgtccgc
     9601 cggcccgttc ctcccccttt cccagggcaa tgtgtttatc cagccccagg ataaagccgt
     9661 atttgcccag attggcgcgg ctgacggttc gggcgcgcag ctgggtcagt tccccttccg
     9721 gggattgggg catgtggtgg taaaggtact gtgtgacggc cagctgaaga atggcgtctc
     9781 ccaggaattc cagccgttca tacgcccggc gcgtttccgg cttgctgtcc gtgctggggt
     9841 gggtaagggc ctgaacgagc agatccggat tgttgaaacg gtaacccagc ttgtcttcca
     9901 gcgcggtgtg attcatcccg gaaatgctag ggccgccgtt ccggaaatgc aactccaaac
     9961 ggagagagct tcccggcggg gacggaattt gttttcccgc gtcatcccgg ccgtccccta
    10021 gctttgacat atgggcggaa gggtatagaa tagtttgcga acgaacgttg gagacgatga
    10081 tgaagaagat tgaaccaaaa gagattcagg ataatgccgt acaattgatc ggggacgatt
    10141 ggatgctggt gacggcgggt tctccggagc atttcaacat gatgacggcc agttggggcg
    10201 gtttggggtt catgtggaag aagcccgtgg cgtttgtagt tatccgcccc cagcgccata
    10261 ccttccgttt tattgaggcc ggggacgagc tgacgctttc ctttttcagc catgagtacc
    10321 ataaggctct gaccgtgtgc ggaacaacga gcggacggga tacggacaag gtggccgcct
    10381 ccggcctgac gccatacgtg acggagaacg gcaatgtaag ttttacggaa gcgcgcctgg
    10441 tgctggagtg ccgcaagctg tacgcggagc ctcttaaccc ggaagccttt ctggataaat
    10501 ctattgtgcc ggagtggtat gccgccgggg atttccataa aatgtatatt gtggaaatcc
    10561 tgaacgtatg ggtgaaggaa tagcgtcccg gaaatgccgc aggcggacgc ctgttcgttg
    10621 tttctgtccg cgctttttca gaggggggca agggttccat cctccagccg gaaggctggc
    10681 agggggcacg gagcatcgtg cagccagtcc agatgggtgg tggtgatgag gctctgcgcg
    10741 tccgctggaa gcgactgcag aaaggctatc cggcgcgtgg gatccagctc cccgaagaca
    10801 tcgtcaatca ggtggatggg tgtatgtccc gtttcttccg tcaggaggga ggactgcgcc
    10861 agcttcatgg agatggcggt ggtgcgctgc tgcccttcgg aagcgaattg agcggcgttt
    10921 ctgccgttca gcgtgatgtc caggtcatcc cggtgggggc cgttctgggt ttgtccgtac
    10981 cggatgtccc ggtccatgga ggcgcacagc cgttcataca ggtctccttc ctccgaggcg
    11041 cggtaagcga tggagacctg ttcctgcctt ccgccgatat tgcggtaggc cagggcgata
    11101 tggggcgcca ggagcgccag cagatgggcg cgcaggtttc tcagttccgt gccgtgcagg
    11161 gccagctggc gcgtgtaggc gtccagctgg agtttgtccc ggtgcctgtg cttgagcagg
    11221 taattgcgcg ttttcagcgc ccggcggtag ctgaacaggg ccagtctgta gcctggatgc
    11281 cactggctgc ccagaaagtc catatatttc cggcgggtgt ccgcgccggc ctgcaccagg
    11341 gaaaggtcgt cattccccat ccataccacg ggatagctgt ccgccaggta gctgcgctgg
    11401 tctttgcggg gctctccgtt gacgcggagg tccggagcgt ccggcgccca caggatgcgc
    11461 cggatttgcc ccggaagttc tccgcggatg ccgaaggatt gttttccgtg ggagaccaga
    11521 ggcccggtcc gggctgtgcg cggggattgc aggcgcagca ggaagcaaac ggcctccagc
    11581 aggctggttt ttccccgggc gttgtttccc aggatgatgg ccccctgctg cggaatctgc
    11641 caggagaagc ttccgtagca acggaagtcc attaatttca gcctggagat catggggccg
    11701 ggaaaagggg ttattccgca gggagggagc ggatggcgtc catgattttg tccgtcaggt
    11761 gctggtatgc atcttttcct ttggcgttga gttccgccgg cgtgaagggg atggggtctc
    11821 ccaccgtgac cgtgacgggg cggagcctgg gaaaccgggc gccgatggga aaggcttcat
    11881 acgcaccgct gatgcgcagg ggctgcacgg gaactttcgt tttgctcagg atgaggccga
    11941 tcccgcccat gccgtcatgg attttaccat ccggcgtgcg ggagccttcc ggaaacacga
    12001 gtacgcgctt gccggatttc agcaggcgta tcacgtgctt gaggctggcg gcatccgggt
    12061 tttcctggtc aatggggata gcctggcaga ggggcagggc ccatttgaaa atgccctgga
    12121 acagcgtctt gcgtgcgaaa aaatagatgc cgtcctcata agaaatgccc agcatgggcg
    12181 gatccagaaa gctctggtga ttgctgacga tgagcacggg gccgtcttcg atgagttttt
    12241 cccggttgac gactttccag gagaagaagg ctttggaaat gcttttgaag agcgtgtaga
    12301 aaacccagta gaaagagttc atctggagga gagtttttgt tggatgttgt cggtgatgaa
    12361 acggacgacc tggtcaatcg tcatgtctga cgtatccacc agaagagcgt caggcgcctg
    12421 cgccagcggg gcggtggcgc gggaagaatc cttgcggtcc cgctccgcga tggagtccgt
    12481 cagtccctcc gcagcgcggc gcgcggccct cacttcctcg gaggcggtga cgaagtactt
    12541 gaacggcgta tccggaaaaa ccacggtgcc tatgtccctt ccttccatca cgacgggttc
    12601 ccggcggtta tattcccgtt gccgttccac cagcagggcg cgtacttccg ggatggccgc
    12661 aatggtggaa acatggtcgt tgacctgctg gctcgtgagt tcttcgccca gcacatgctg
    12721 tccgcacaga actacggatt ggctgccgtc cttgccgaag gagaggggca cggacggcag
    12781 agattccaga acggctgctg tatccgcggg gttgatgccc tgttccagca tgtaccaggt
    12841 aacggcccgg tacatggccc cggtgttgat gaacgtatag ccgaggcggt ccgcgatgag
    12901 cttggcgacg gtggattttc cggaggcggc ggggccgtca atggcgatgg ctggatgcat
    12961 gagtgtcttc tgagttggaa atgggggcta aagccgtttg aattgtagct ttgagccctg
    13021 tggaaatcaa gactgcgttc cgaagggcgt tgcaaaaaga gtttcacttt ttcccgtaaa
    13081 tccgttatac agcggggcat ggcccagctc aaacacccga agatggtgga catcagagac
    13141 attttggacg agaatacgcg tctgcctgct ctggtggccg cgtccgccga aaagctgctg
    13201 ggcctggaac gcctgaacaa ggcgtacgac aagatcgtgc gcgacaaaga atccggttct
    13261 caggaaaatt tctttcagct tgcctccagg catttgaacc tgaagcttca gctgcgcccg
    13321 ggggacctgg aaaatattcc taagaaaggg cctgtcgtcg tcgttgccaa tcatccgcac
    13381 ggcttgtcgg acggcatcat gttcggggag ctgcttaccc gcgtaagaga ggatgtccgc
    13441 atcctggtca acgagcagct ttccctgtgc ggggagctgg atccctggct catcaaggtg
    13501 gacgtgtatg aagatgagaa cgcccggcgc aaaaatcttt ccggcatgcg caagatgatt
    13561 tcctggctgc ggcagggcgg ggttctgggc attttccccg ccggcacggt ctccagtttt
    13621 tccctggctc acaaaagggt gacggacgac ccctggaacg cgaatatcgc cgccattatc
    13681 cgcatgacga aagcgacggt ggtg
//
