LOCUS       gnlProkkaKNPJIOME_1    22598 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KNPJIOME_1.
ACCESSION   gnlProkkaKNPJIOME_1
VERSION     gnlProkkaKNPJIOME_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 10:10:40
            Original ID  :: gnl|Prokka|KNPJIOME_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 771207
            Orig. end    :: 793805
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22598
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12598]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12598
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..22598
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22598
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             complement(729..1376)
                     /locus_tag="ctg1_719"
                     /transl_table=11
                     /translation="MCAVTILSHKTISSALLLLSVMSIAPLYNGCTMSDYIFESLGFSS
                     WSEDGAHISVIPGVVLYFAALIWCAASFRRTLPAVGLFLIFLSMGVSSSISPVTEYAAF
                     SLKQFAPERKAVEYLKRRSECSHLIERKKASMSCTIYINYYGKGEQTISVTPDLSENVK
                     GVTFKSKTFTVMPRSKTIIRTRFTGFYKGKAASDSGWSSEPDLKVASLHTAE"
     CDS             complement(1440..2399)
                     /locus_tag="ctg1_720"
                     /transl_table=11
                     /translation="MIHITAITTHNEILDNIPLSRTEQPDIAWYWIDFFGAEMHETELL
                     RDYFHFHPLAIEDCFQQMQRPKIDHYDGYRFYVLHALNPDTLEMEEVDIFQSDRFIVSF
                     HLHESPGISRVRERFFASPGLAKKGPGHITYMIMDQLVDEYFPVLYKIEDRLNEIEDSR
                     THKSYGTLMNEVFELRTDLLNLRRTIIPMRDLMYRILSLDHVKESRETKAYFSDIYDHL
                     LKLAELIESNRDMTSDLRDSYVTLNSNRMNAIMMTLTIVSTIFIPLTFIAGVYGMNFDN
                     MPELHWKYGYFIVLGVMAALVAAMLFWFARKGWFNIFK"
     CDS             2506..3369
                     /locus_tag="ctg1_721"
                     /transl_table=11
                     /translation="MWEETVSVTPPYHFDKVLERLSLDPLNAVDLTARSIKVPLRTRDG
                     KLSVIMVQAKGTAIDPVFLVSGETDREEMIERIKHIFQWEQPLQPVLDHFSKTNLSALF
                     EEHAGTPLVLEYDVYNCLMKCIIHQQLNLSFAFTLTERFVHAFGEQKDGVWCYPEPKTI
                     AALEYQDLRELQFSMRKAEYAIDLSRMIADGALNLAELPQLSDEDIMKKLITIRGIGPW
                     TVQNVLMFGLGRPNLFPLADIGLQNAVKRRFALEDKPSKDLMLQVSREWAPYLSYASLY
                     LWRSIE"
     CDS             3541..4941
                     /locus_tag="ctg1_722"
                     /transl_table=11
                     /translation="MNQHQKKAPAELKIGQTFPLTIKRLGINGEGVGYFKKKVVFVPGA
                     LPGEEVVAEATNVQPKFSEARVKKIRKSSEHRVTPPCPVYEQCGGCQLQHLAYSQQLRE
                     KRDIVIQSLERHTRFNVEEMDIKETIGMDNPWNYRNKSQFQVGRSQSGSIIAGLYGLDS
                     HKIVPIKECIVQHPATNKTTGIVRRILEKHNVSVYNERTKKGDVRTIVTRVGFETGEVQ
                     VVLVTAKETLPNKDEIVKAIQNRLPEVKSIIQNINGARTSVIFGDKTKALAGSHAIQEV
                     LGDVSFELSARAFFQLNPEQTVKLYDEVKKAAQLTGKEKVVDAYCGVGTIGMWVSSGAK
                     EIRGMDVIKESIDDAKKNAKKHGIKNAAYVTGTAEHWLPKWTKEGFRPDVVIVDPPRTG
                     CDGTFLDTIKKVKPIRFVYVSCNPSTLAKDLQALSKDYRVEYIQPVDMFPQTAHVEAVA
                     KLVLKSSN"
     CDS             complement(6367..7749)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 237.3; E-value: 6.8e-72)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_723"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.6e-42, bitscore:
                     143.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRRISIVFIFVIVSSLQPVSSRAEESNHDESIIINLDSKISE
                     STINKVQEKYSNIETNYIKELDLLVINNIKPSQFSAIKDIAKEKLDANEIIEDKEISLP
                     EKSKQIPAKVASSSQFTEDNDTLYDSWLWNIKQVTNDYRSYQINKGSHNTKVGIIDSGI
                     DFNHPDLKKNIVDTGKSFVPVEDNTQDFYGHGTSVAGIIAANGDVKGVGPNLGLVPYKV
                     FDKNGKSKRSWVISAIVKATEDNMDVINLSLSTFLSKKDKDDRETIKLFEKAFKFARKH
                     NTLIVAAAGNHGYDISNSKKLAQQLGKPKDNILHLPGGDNDVITVSATTAQNTKASYSN
                     YGKNISIAAPGGDLDTNKIDLYSLVWTTSPVNIPQTPLSKSLGFQKGYEPTLGTSVAAP
                     IVTATAALLKTEYYEKYGEEMPNRKVEENLYQNTDHVENLDKNEVGSGIVNAYESLLNI
                     ER"
     CDS             8201..9973
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     266; E-value: 4e-81)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 344.6; E-value:
                     1.8e-104)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_724"
                     /transl_table=11
                     /translation="MMTNPNFKSKEFFFLLSKTRPNIRLFILAIFLSGLSAIASTLVPH
                     YLKSLIDYYNIHEKINLWDLLGLLGIFLSSGVIGAVGSYMLSVVGYNVVANLRNLLWEK
                     IVILPVEFYDKNRSADIASRFVNDTTVIYNLVSNSFSQFINAILIVLFCGFWLFYYDWQ
                     LTLVIVVAIPVYLLIFIPLGRILSKLSKMTQSLTGELNVRAVETISAIRLVKSSTAEKL
                     QVEKGKEDVEALRSIGLKQTKWMVILNPIINLMMMLIIISIIGFGGVKLANGSLSPGTF
                     IAFLTLMFYIMGPLNNFGLFFTQIQKTIGATERISQLIYEQGEDQHKGKELAETNKDLV
                     IENLSFCYSNEDKAFSLKNINLIIKRGSVNALVGPSGSGKTTIISILERYYKPNSGNIY
                     FGDENIELFSLKSWRSQIGYVAQNHDLISGTIRDNLIFGLENPPNEKRIVEACKKAYAW
                     QFISELPNSLETNIGEKGLNLSGGQRQRIAIARMFLKNPNIIFLDEATASLDSHSERIV
                     NEAMKKLMKDRTAIIIAHRLSTIINADNIIFMENGEITGQGNHWELKHSHKLYHQFCEQ
                     QFKEDSTDPLVLTN"
     CDS             10001..12598
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 73;
                     E-value: 4.7e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_725"
                     /sec_met_domain="micKC (E-value: 1.1e-144, bitscore: 481.2,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 7.9e-17, bitscore: 59.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 9e-08, bitscore: 29.0,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLVYFQHMSEDSKYYIEKSPNAETDPYEVHNIPNYYTVSTEY
                     KSPWKFYNNPNHPLKEQGWKIHVSATMNNAQDILEVVSQIIFKHQIPFKHIKDKQSLFN
                     MNSKHGNRTSSGKFIAIYPSSNNMFFRLLNELYEELKHYENGPYILNDKSWKDSNIYYR
                     YGAFKNIYNERGELCIKDENGNLIPDNRQPYYKIPEFVSDFDQYLDTKNNLLDTQDVSN
                     FNDYEFQGVLRFNNGGGIYTGIRKSDGKKVVIKEGRPKVGLDGQFNDAIDRLNIEYEAL
                     NKLTDVEGVVNVLDYFKAWKHVFLVEEFVEGVTLQTWCAINYPFNVENDKNEYISKVKK
                     IINSLVKTIKQVHSKDVGMGDLQPQNIMITPESNVKIIDFEAASTLSEENGALQTIGYT
                     NKKNKNHKERDWYALKKVLRFCILPIGPVADIEETIKKKHDMWIEDEFGKDVYQYVVNI
                     ENLCDKYLSDTKEKIFKNSYDSKIQKEMDMSKVIKGLRNSIESNILPNSSLIHGDVRQF
                     VMPSGKLNVLTGGTGAALALYRSGNVSKEVWDWIENVLLEKLNVLNDDVGLFTGRAGIA
                     ATLYELGYIEQAMDLFNNLSYEDMKDISLRSGLSGIGLSLISLYMEENNDDFLVTSEKI
                     ADQIENRIIEDDKLSVTDFAAVPIGLIDGWSGISLFYAALYSVTKNEKYYLKSKEYIER
                     DLKHCKVDEETNTLQTYDDQNPRLLPYLSGGSIGIGIAIWYLNYVKNNNLFREELEQII
                     NLNKVRIAYSGGLFDGIGSFLLIPSMTKEKNETSQHIELALRKLELFLIRKDDQVLFPG
                     NFSFRLADDYYSGSAGIILGINSIQFSNPLYWLPIIKIDSFLRKTKKELLLNN"
     CDS             12690..12809
                     /locus_tag="ctg1_726"
                     /transl_table=11
                     /translation="MKEVLVLQQFDEKSEVEPTAWTVTLTTISVTLSTLSNHC"
     CDS             12861..12989
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_727"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGTEVEASKGKGGLLTLITTIVGSSTISNNC"
     CDS_motif       12861..12932
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="ctg1_727_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12933..12989
                     /prepeptide="core"
                     /locus_tag="ctg1_727_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1724.0"
                     /monoisotopic_mass="1723.0"
                     /core_sequence="LLTLITTIVGSSTISNNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[12860:12932](+)"
                     /alternative_weights="1742.0"
                     /alternative_weights="1760.0"
                     /alternative_weights="1778.1"
                     /alternative_weights="1796.1"
                     /alternative_weights="1814.1"
                     /alternative_weights="1832.1"
     CDS             13016..13135
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_728"
                     /transl_table=11
                     /translation="MNEVLELQQLSKGSEVETAGWTLLTTLIGTSTISNSCNK"
     CDS_motif       13016..13066
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MNEVLELQQLSKGSEVE"
                     /locus_tag="ctg1_728_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13067..13135
                     /prepeptide="core"
                     /locus_tag="ctg1_728_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.30"
                     /molecular_weight="2120.4"
                     /monoisotopic_mass="2119.2"
                     /core_sequence="TAGWTLLTTLIGTSTISNSCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEVLELQQLSKGSEVE"
                     /leader_location="[13015:13066](+)"
                     /alternative_weights="2138.4"
                     /alternative_weights="2156.4"
                     /alternative_weights="2174.4"
                     /alternative_weights="2192.5"
                     /alternative_weights="2210.5"
                     /alternative_weights="2228.5"
                     /alternative_weights="2246.5"
                     /alternative_weights="2264.5"
     CDS             13156..13287
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_729"
                     /transl_table=11
                     /translation="MRDVLELQQLNEGTEVEASKGKGGLLTLITTVVGTSTISNNCG"
     CDS_motif       13156..13227
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MRDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="ctg1_729_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13228..13287
                     /prepeptide="core"
                     /locus_tag="ctg1_729_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1781.1"
                     /monoisotopic_mass="1780.0"
                     /core_sequence="LLTLITTVVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[13155:13227](+)"
                     /alternative_weights="1799.1"
                     /alternative_weights="1817.1"
                     /alternative_weights="1835.1"
                     /alternative_weights="1853.1"
                     /alternative_weights="1871.2"
                     /alternative_weights="1889.2"
     CDS             13431..13559
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_730"
                     /transl_table=11
                     /translation="MRDVLELQQLNEGTEVEASKGKGGLLTLITTVVGTSTISNNC"
     CDS_motif       13431..13502
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MRDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="ctg1_730_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13503..13559
                     /prepeptide="core"
                     /locus_tag="ctg1_730_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1724.0"
                     /monoisotopic_mass="1723.0"
                     /core_sequence="LLTLITTVVGTSTISNNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[13430:13502](+)"
                     /alternative_weights="1742.0"
                     /alternative_weights="1760.0"
                     /alternative_weights="1778.1"
                     /alternative_weights="1796.1"
                     /alternative_weights="1814.1"
                     /alternative_weights="1832.1"
     CDS             13709..13840
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_731"
                     /transl_table=11
                     /translation="MRDVLELQQLNEGTEVEASKGKGGLLTLITTVVGTSTISNNCG"
     CDS_motif       13709..13780
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MRDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="ctg1_731_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13781..13840
                     /prepeptide="core"
                     /locus_tag="ctg1_731_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1781.1"
                     /monoisotopic_mass="1780.0"
                     /core_sequence="LLTLITTVVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[13708:13780](+)"
                     /alternative_weights="1799.1"
                     /alternative_weights="1817.1"
                     /alternative_weights="1835.1"
                     /alternative_weights="1853.1"
                     /alternative_weights="1871.2"
                     /alternative_weights="1889.2"
     CDS             14095..14238
                     /locus_tag="ctg1_732"
                     /transl_table=11
                     /translation="MNNVLALQQLNNSAEVEPQVGPTITTITVIPTMVISLISNYCDNH
                     AS"
     CDS             14302..14586
                     /locus_tag="ctg1_733"
                     /transl_table=11
                     /translation="MDKVNKKRPLYKRSWFQTVLAFLVSQLYFNFVELTGWGPKYREMN
                     GFPANIVELDFFQKYLSFYENPWFNIVTVFLGVFTVIQIITGITKDIRN"
     CDS             15441..16493
                     /locus_tag="ctg1_734"
                     /transl_table=11
                     /translation="MVSFLILEYMMHPYSLMKGYEFIMIDNFWRELPRPFFVLAPMEDV
                     TDVVFRHVVSEAGRPDVFFTEFTNSESYCHPDGRDSVRGRLTFTEDEQPMVAHIWGDKP
                     ENFRQMSIGMAELGFKGLDINMGCPVPNVAGNGKGSGLICRPEVAAELIQAAKAGGLPV
                     SVKTRLGYTDVDEWRGWLTHVLKQDIANLSIHLRTRAEMSKVDAHWELIPEIKKLRDEI
                     APDTLLTINGDIPDRETGLKLAEQYGVDGIMIGRGIFTNPFAFEKEPREHSSKELLDLL
                     RLHLDLHDKYSKLEARPYKPLPRFFKIYLRGFRGASELRNQCMNTKSTDEVRALLDDFE
                     RKYLDGMEQQ"
     CDS             16686..17138
                     /locus_tag="ctg1_735"
                     /transl_table=11
                     /translation="MKRLCIIPCGKKKIWDIHPDTGPIRAEDAYLSPFHQACERYAKAF
                     FDEWVILSAKHGFLRPDDTVPENYDVTFGTGHPEIMTAEELRRQFYEKGFSNTKELIML
                     GGKKYRSVLNAVIGEHQHLSWPLSSYKGIGYMLQALNRAVEEKQEL"
     CDS             17511..18512
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_736"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-05, bitscore:
                     21.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELLKREGLSLTEEKALWMYQKMLEIRGFEDKVHELFAQGVLPGF
                     VHLYAGEEAVAVGVCAHLHDGDSITSTHRGHGHCIAKGCDLDGMMAEIFGKATGLCKGK
                     GGSMHIADLNKGMLGANGIVGGGFTLACGSALTAKYKQTNNVSVCFFGDGANNQGTFHE
                     GLNLAAVWDLPVVFVAENNGYGEATTFEYASACDSIADRAAAYNMPGVKVDGKDILAVY
                     QAAEEAIERARNGEGPSLIECMTYRNYGHFEGDAQTYKTKDERTEHIKEKDAIQGFKNY
                     LLKETDANKLSDIEQRVSESIEKAVSFSEDSPYPKESELLTDVYVSYEKGGM"
     CDS             18514..19542
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110:1-deoxy-D-xylulose-5-phosphate synthase (Score:
                     344.3; E-value: 7.4e-105)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_737"
                     /transl_table=11
                     /translation="MARVISMSDAINEAMKLAMRRDENVLLIGEDVAGGAAVDHLQDDE
                     AWGGVLGVTKGLVQEFGRSRVLDTPISEAGYMGAAMAAASTGLRPIAELMFNDFIGTCF
                     DQVINQGAKFRYMFGGKAQVPITVRTTYGAGFRAAAQHSQALYGLFTSIPGLKTVVPSN
                     PYDAKGLLLAAIEDNDPVFFFEDKTSYSMKGEVPEGYYTIPLGKADIKREGGDITLFAI
                     GKQVNTALEAAAQLSEKGIEAEVLDPRSLSPLDEEAIFTSLEKTNRLIIIDEANPRCSI
                     ATDIAAIVADKGFDLLDAPIKRITAPHTPVPFSPVLEDQYLPTSDQIVSVTLELLGEPA
                     MN"
     CDS             19557..20750
                     /locus_tag="ctg1_738"
                     /transl_table=11
                     /translation="MAVKVVMPKLGMAMKQGEVSVWNKKVGDQVEKGESIASINSEKIE
                     MEVEAPESGTLLHIKVKEGEGVPPGTAICYIGENGEKVQEKEAPASENAGEPQAEPETI
                     PAPKAGKERKHRVKISPVARKMAEKAGLKIDTLNGTGPGGRIVKADVIKAMKTEAEPRS
                     SVQTAQPEGKPASAMRKVIADRMHKSLQNSAQLTLTMKADITDLVKWQKQLADSAKKRS
                     CVKLTVTHFVSRAAVLALKQHPELNSSYQEERIITYPHVHLGMAVSLENGLVVPVIRDA
                     EKLSFLELADQISTSARRAREGNASGDDLHGSTFSITNLGGYGIEHFTPILNPPEAGIL
                     GVGASYETPAFKGDELVKSTVLPLSLTFDHRVCDGAPAADFLKTVKALLEEPAGLIL"
     CDS             20766..22145
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175:pyridine nucleotide-disulfide oxidoreductase
                     (Score: 469.7; E-value: 1.3e-142)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_739"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.5e-70, bitscore:
                     233.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLAIIGGGPAGYAAAVTAARRGAEVVLIDKGPLGGTCLNEGCIP
                     TKSLLESANVLDKIRHANTFGIELPQNITLNWARMQGRKRQIVNRLVQGIQYLMKANKI
                     RVISGTASFLSDQTLLIEGEGGEKEILEAGRILIASGSEPAELPFAPFDGDWVIDSKDV
                     LSLQQIPSSLLIVGGGVIGCEFASLFSRFKTKVTMIESADRLLPAEDEDIAVAFEDSLR
                     DSGVDIQTKASFQRIDRERKTAVWTKDGKEIEAQADHILVAIGRKPRLQELNLEQAGIL
                     YSPRGIEVNDHMQTNLPHIYACGDAAGGMQLAHAAIHEGITAASHATGKDSKANMRAVP
                     RCIYTSPEMAAVGLTETQAREKYGDVKIGECSFSANGKALIKHQHGGKMKIIAEPEFGE
                     IVGVSMIGPDVTELIGQAVMLMNGEMTADMSEHFIAAHPTLSETLQEALLNVTGLAVHS
                     V"
ORIGIN
        1 atttctgctc ggacatgatg gttccgtaat tttgatagac gggagagcca aatagcgcgt
       61 tggcgatttc taaaaattgt ttttgttcca ggccgtactt ctccatcatt aagaatgatt
      121 cagataacgc ctccagcata gaaacgagca agaaattgac gctgattttg gccgcgttgg
      181 ctgttttggt ttcttcaccg gtgtcaaata cttgctgacc caggcttcta aacagcggtt
      241 cggccttttt cttcgcttcc tgagggccgg ctgtgatgat gcggagctcg gccttctcag
      301 cagcatcggg acggccgagg acgggagcgg caataaagga ctgccctctg ctcgaatgcg
      361 cagcggaaag ctgttctgac agcgccgtgc tgatggtgct cattgaaata tgaatacctt
      421 tttcagataa cccggcaata atgccatcag gcccgaaagt cacacctgtt acggcttcat
      481 cgtccgacag cattgacagc acaatgtccg catgttcagc tgcctgacgg ggcgttttgg
      541 catattcggc ccctttctcc agcagatcag ccgctttttc tttcgtccgg ttatagacag
      601 tcagactgta tccggctttc attacatttt cggcgatggg gcgtcccata ttgccgagtc
      661 cgacgatggc gatcttcatt tgcagtccct ccaatgaaat attttccatc attatacatg
      721 caaaacgttt attctgctgt gtgcaggctt gcaactttta ggtcaggttc tgaagaccat
      781 ccgctgtctg atgcggcttt ccctttataa aagccggtaa accgcgtcct gatgattgtt
      841 ttcgaccggg gcattacagt gaaggttttt gatttgaatg tgacgccctt tacgttctca
      901 gatagatccg gtgtgacaga tatggtttgt tccccttttc cataataatt gatataaatc
      961 gtgcagctca tgctcgcttt tttgcgctca atcagatgac tgcattcact ccggcgcttc
     1021 agatattcga cagcctttct ttcaggcgcg aactgtttta aggaaaaagc ggcatattca
     1081 gtgacaggac tgatgctgga agagaccccc atgctgagaa agatcagaaa cagccccaca
     1141 gcgggaagcg tccgtctgaa cgaggcggca caccagatta acgccgcaaa atatagcacg
     1201 accccgggaa tgacggagat atgggctcca tcttcagacc aagaagaaaa gccgagcgac
     1261 tcaaagatgt aatcagacat cgtacagccg ttatacagcg gggcaatgga catgacactg
     1321 agaagcagaa gggcggaaga aatggttttg tgagaaagaa tggtaacggc gcacacctct
     1381 ttacgttttt ttccaacata tcatgttttc acaaaaaaaa gaacagccgg cagccgttct
     1441 tacttgaaaa tattaaacca gcctttacgg gcgaaccaaa acagcatggc ggccacaaga
     1501 gcggccatta cgcccaaaac gataaaatac ccgtatttcc aatgaagctc aggcatgtta
     1561 tcgaaattca taccgtaaac tcccgcgatg aacgtgagcg gaataaaaat ggtcgagacg
     1621 atggttaacg tcatcatgat ggcgttcatc cggtttgaat tcagcgttac atagctgtcc
     1681 cgcagatctg acgtcatatc acggtttgac tcgatcagct cagccagttt taacaggtgg
     1741 tcataaatat cgctgaaata tgcttttgtt tcacggcttt cttttacatg atcaagactc
     1801 aaaatccgat acattaaatc gcgcatcgga atgattgtcc gcctcaggtt caaaagatca
     1861 gtccgcaatt caaacacttc attcattaaa gtgccgtaag atttatgtgt tctgctgtct
     1921 tcaatttcat tcagccggtc ttcaattttg tacagcacag ggaaatattc atcgacaagc
     1981 tgatccataa tcatatacgt tatgtgtccg ggcccttttt tggctaaccc cggagaagcg
     2041 aaaaaccgtt ctcttaccct tgagatgccg ggcgattcgt gcagatggaa gctgacgatg
     2101 aaacggtcgg actgaaaaat gtccacctct tccatttcca gtgtgtccgg gttcaaggcg
     2161 tggagcacat aaaaacggta gccgtcataa tggtcgattt tcggccgctg catttgctga
     2221 aagcaatcct cgatcgcgag cggatgaaaa tggaaataat cccgcagcag ctcggtttca
     2281 tgcatctcgg ctccgaaaaa atcaatccag taccatgcga tgtccggttg ttctgtacgt
     2341 gataggggga tattatctaa tatctcatta tgtgttgtga ttgcggttat atgtatcata
     2401 aacaaccctc cgcctgccat tatatcatgc ggcgttatga agaaaagtat acgaattgcc
     2461 gccggaacgc ttcgtgatat acttggacaa aaaggggtgg agcatatgtg ggaggaaacg
     2521 gtttcggtca cgccgccgta tcattttgat aaagtgcttg aaaggctgtc actcgatccg
     2581 ctgaatgcgg tcgatcttac agcaaggtca attaaagttc cgctcagaac acgggacggc
     2641 aaactgtcgg tcatcatggt tcaagcgaaa ggcaccgcca tagatccggt tttcctcgtc
     2701 agcggcgaaa cggaccgcga ggagatgatt gaacggatca aacacatttt tcagtgggag
     2761 cagccgcttc agcctgtgct tgatcatttt tcaaaaacaa atctgtctgc gctttttgaa
     2821 gagcatgcgg gaaccccgct cgtgctggaa tacgatgtgt acaactgtct catgaaatgc
     2881 atcatccacc agcagctcaa cctgtccttc gcttttacct taacggaacg gttcgtccat
     2941 gccttcggcg aacaaaaaga cggcgtctgg tgctaccccg agccgaaaac gattgcggcg
     3001 cttgagtatc aggacttgcg ggagcttcag ttcagcatga gaaaagcgga atatgcgatt
     3061 gacctttcac ggatgattgc agacggagcg ctcaatctgg cggaacttcc ccagttatcg
     3121 gatgaagaca ttatgaaaaa gctgatcacc atcagaggca tcgggccatg gaccgtccaa
     3181 aacgtcctca tgttcggcct cggccgcccg aatctgtttc ctttggcaga tatcggcctg
     3241 caaaacgccg tcaaacgccg cttcgccctt gaggataaac cgtcaaaaga cttgatgctt
     3301 caagtaagca gggaatgggc gccgtattta agctacgcgt ccttgtattt gtggagaagt
     3361 attgaataaa aacaagatgg cttaccaatg gcatctgatc gcttccgagt atttttggaa
     3421 acttccggtg aaaaacatga aggaaccgcc ggctgcatgt tatactgaaa agatgtgata
     3481 tttcaaatca gccgttttcc catgaggaag gctttattat agaaatggag agagtaaaac
     3541 gtgaatcaac atcaaaaaaa ggcgcctgcc gaattgaaaa tcgggcagac atttccgctg
     3601 accatcaaac gcctcggcat taatggagag ggcgtcggct attttaagaa aaaggttgtc
     3661 ttcgttcccg gcgctctgcc cggcgaagaa gtcgttgccg aagcaacaaa cgttcagccg
     3721 aaattttcag aagcacgcgt caaaaaaatc cgcaagtctt ctgaacaccg cgtcacgccg
     3781 ccttgtccgg tatacgaaca atgcggcggc tgccagcttc agcatctggc ctacagtcag
     3841 cagcttcgcg aaaaacgtga tatcgtcatt cagtctctgg aacgtcatac gagattcaat
     3901 gttgaagaaa tggacattaa agaaaccatc ggcatggaca acccatggaa ttaccggaac
     3961 aaaagccagt ttcaagtcgg acgctcgcaa agcggcagca tcattgccgg cttatacgga
     4021 cttgattccc ataaaatcgt tccgattaag gaatgcattg tccagcatcc ggcgacgaac
     4081 aaaacaacgg gtatcgtccg ccgcattttg gaaaaacaca acgtatctgt ttataacgaa
     4141 cggaccaaaa aaggcgatgt ccgcaccatc gtgacaagag tcggttttga aacaggcgaa
     4201 gtgcaggtcg tgcttgtcac tgcgaaagag acacttccga ataaagacga gatcgtcaaa
     4261 gccattcaga accgtctgcc cgaagtgaaa tcgattattc aaaacatcaa cggcgcgcgc
     4321 acatccgtca ttttcggcga caaaacaaaa gcgctggccg gaagccatgc cattcaagag
     4381 gtgctcggtg acgtgtcatt tgaattgagc gcacgcgctt tcttccagct caaccctgag
     4441 cagacggtca agctgtatga cgaagtgaaa aaagcggcac agctgaccgg aaaagaaaaa
     4501 gtcgttgacg catattgcgg cgtcggtacg atcggcatgt gggtctcaag cggggcgaaa
     4561 gagatccgcg gcatggacgt cattaaagaa tcaattgacg atgcgaagaa gaacgccaaa
     4621 aaacacggca tcaaaaacgc ggcatatgtc acaggaacag ccgaacactg gctcccgaaa
     4681 tggacgaaag aaggcttccg ccctgacgtg gtcatcgtcg acccgccgag aacgggctgc
     4741 gacggaacat ttttagatac catcaaaaaa gtaaaaccga tacgcttcgt ctacgtatcc
     4801 tgcaatcctt ccacactggc gaaagacttg caggcgctgt cgaaggacta tcgcgtcgaa
     4861 tatattcagc ctgtggatat gtttccgcag acggctcatg tggaagctgt ggcgaagctt
     4921 gtattgaaat cgtctaatta aaaaacgatt cctgatcaga tctggatttc ggcagaatga
     4981 acattgccga tttccgggtc tttttcatag ggagcctttg ccctgactgt cttttctcag
     5041 agaactttat tttcactgac gaaaagagct gaaaaaacgt gcggaaaccc tcatttttta
     5101 gatcaattcc taaagctgta accattcaac agtaaagtat ctatcatgct gctccataaa
     5161 catattcttt tttccgtttg gaaacggtat tacagacaaa atatgaagag caataacgac
     5221 tcgttcaagt ctcgtgaata cttgtaactc ctgtgaatat tttgtaaact ccttttttaa
     5281 agaataaagc ccctgttgct aactatacgt gaataattgc tccttataat gatctatcgc
     5341 ttgattcata caatgttaaa gtgccgataa ggcaatgcgt ttatccggat cagcagataa
     5401 aatcaatatg atctttaatt ggactagggg tttgataata gtcaacaatg taataaccac
     5461 tttttggctt agcgtagaca acatgtgctg ctctagttct agtaaggcct ttgcaactgt
     5521 cctatgacag gtgcattttt tcatgtatta ataatagttg gcatcgttac atttgcttaa
     5581 ttagctaatt gttcactatg attatgaaat gatttgttaa gggtgaattt gaatgaaaag
     5641 caatataaaa agaggtctga taattggatt tattggagcg acttgtttta gtttacatta
     5701 cttgcttcaa gtatcgctgt ccctattttg atgagacaat tgttggattg ggtaggacag
     5761 caaaagggct gcatacgtgg attttgtaag tatgattggg aatggtatta caaagtaaca
     5821 ccgagaataa agccgaataa caagagaaaa gcactgttga ttgggaagag agataaagag
     5881 tgtttgggac tgctaaagaa ggagtaataa tagtatgaat tgttttacaa acagaaagaa
     5941 aaccaactag agtgagccct taaattttag gagaacttta tgagtcggtt catggttccg
     6001 taatcaaaat ttagtccgta cacaaaatcg tatagaggga tttagggtaa ggaaggtaag
     6061 tgggctattg aagatagatt aaagcaaggg aaagaattgg tctgtttata aggtgctgct
     6121 acatgctggg ttttgtgcga taaagaaatc aacaatagct aaagaattga atactcaggc
     6181 tgaaataaaa tatgacacaa gcaacttagt aatattaagt tgcttgtgaa ctcaacttat
     6241 ttagttattc tcatatcccg taaatacagt ttttttcatc tctacttcat cattattatc
     6301 gtctagtaat ctttttttac taatcaaagt atttttagtg aaagttcgat aactgcttaa
     6361 tatcttctat ctctcaatat taagcaatga ttcgtaagca tttacgatac cgctacctac
     6421 ttcattctta tctaagtttt caacgtggtc tgtgttctga tataagtttt cttcaacctt
     6481 acgatttggc atttcctctc catatttttc gtagtattct gtctttaata gggctgctgt
     6541 agcagttact attggagctg ctacacttgt ccctaaagta ggttcatatc ccttttgaaa
     6601 gcctagtgac ttacttagcg gagtttgcgg gatattgaca ggggaagtag tccataccaa
     6661 gctatataga tcaatcttat ttgtatccag atcaccacct ggggctgcaa ttgagatgtt
     6721 ttttccataa tttgagtaag aagcttttgt attttgcgct gtggtggcag atacagtaat
     6781 tacatcgtta tctccaccag gaagatgtag gatattgtcc tttggtttac ctaattgttg
     6841 tgcaagtttt tttgaatttg agatatcata tccatggttt ccagctgctg caacaattaa
     6901 agtattgtgt tttctagcga atttaaaagc tttttcaaaa agttttatag tctctctatc
     6961 atctttatct ttttttgata aaaaagtaga taaacttaaa ttaattacgt ccatattatc
     7021 ttccgtagct ttaacaattg cgcttataac ccaacttctt ttagatttac cgtttttatc
     7081 aaatacttta tacggcacta aaccaagatt tggtccaact ccttttacat ccccattagc
     7141 agcaattatt ccagccacag aagttccatg cccataaaag tcttgtgtat tatcttcaac
     7201 tggaacaaaa gactttccag tatctacaat attttttttg aggtctggat gattgaaatc
     7261 tatgcctgaa tcgattatcc ctacttttgt attatgagat cctttattta tctgataact
     7321 tcgataatca tttgtaactt gcttgatatt ccataaccaa ctgtcataaa gagtgtcatt
     7381 atcttccgtg aattgtgatg aagatgccac tttagcagga atctgtttac ttttttcagg
     7441 aagagaaatt tctttatcct caataatttc atttgcgtct aatttttctt tagcaatatc
     7501 tttgattgct gagaattggc ttggttttat attatttatt accaataaat ctagttcttt
     7561 aatataattt gtttctatat ttgaatactt ttcctgaacc ttgtttattg tcgattcact
     7621 aatttttgag tcgaggttaa ttatgataga ttcatcatga tttgattctt cagcacgaga
     7681 gctaacaggt tgtaaactag atacaattac aaatatgaaa actatcgaaa ttcttcttaa
     7741 attcttcatt ttttatactc ctttctcttt atacatttca ttataagatt gtatataatt
     7801 caccctccca ttccaaaaaa tgaaatataa gtatatttaa ttcaatttta taaaatataa
     7861 gtaaatcagt caatgcatat ttttctaatt agaagtgatt atccccggaa acgtcccttt
     7921 agtatgatta atttaaattt ctttttattc ttttatacta cgcctatggt tttgtgggca
     7981 gaaatattaa gagtgaatat acatttcgta atatacaaaa gtagaataat gtataaccaa
     8041 agacctgttt ttttataatt tgtaaaatta tatattgact tacagttatt gagtgtgaaa
     8101 tattgtttat aggaaaatca ggaaagatat ggcgtatgtc atttcaagag tcattcgata
     8161 taaaaagttg agacattgga attaaacgaa agaggtgaaa atgatgacca accctaattt
     8221 taaatcgaaa gagtttttct tcttactgag taaaaccaga ccgaatataa gattatttat
     8281 attggcaata tttttaagtg gattaagcgc aatagcttct accttagtgc ctcattattt
     8341 aaaaagtcta atagactatt acaatattca tgaaaagatc aatttgtggg acctattagg
     8401 actgctaggg atatttttaa gcagcggagt aattggggca gttggtagtt atatgttaag
     8461 tgtagtagga tataatgttg tcgcaaatct cagaaattta ttatgggaaa agatagttat
     8521 actgcctgta gaattttacg ataagaatcg ttctgcggat atagcaagta gatttgttaa
     8581 tgatactacg gtgatttaca acttagtaag taactctttt tcgcaattta tcaatgctat
     8641 attaatagtg cttttttgtg gattttggtt gttttactat gattggcaat tgacactagt
     8701 gattgtcgta gcaattccag tttatttatt aatttttata cctttaggaa gaattttatc
     8761 taaattatct aaaatgacgc aaagcttaac aggtgaatta aatgtaagag ctgttgaaac
     8821 aatatctgca ataagactgg ttaaatcttc aactgcagaa aaattacaag tagaaaaagg
     8881 aaaagaagat gttgaagctt taagaagcat aggcctaaag cagacaaaat ggatggttat
     8941 tttaaaccct atcattaatt taatgatgat gcttatcatt attagcataa ttggattcgg
     9001 aggggttaaa ttagccaatg gaagtttatc gccaggaacg tttatagcat ttctgacact
     9061 tatgttctat atcatgggtc cacttaataa ctttgggcta ttctttactc aaatacaaaa
     9121 gacaataggt gcaacagaaa gaatttctca attgatatat gagcaaggag aagatcagca
     9181 taaaggaaaa gaattagcgg aaaccaataa agatttagtg attgaaaatt tatcattttg
     9241 ctacagtaat gaggataaag cattttcctt gaaaaatatt aatttaataa taaaaagagg
     9301 aagtgttaat gccttagtag gtcctagtgg tagtggtaaa accacaatca tctctattct
     9361 ggagagatac tacaagccca acagcggaaa tatttatttt ggtgacgaga atattgagtt
     9421 attttcatta aaatcatggc gtagccaaat aggatatgta gcacagaatc atgatttaat
     9481 aagcggtact attagagaca atctcatctt tggtttagaa aatcccccaa atgaaaaaag
     9541 aatagtagaa gcatgtaaga aggcatatgc atggcaattt ataagtgaat tgcctaacag
     9601 tttagaaact aatattggag aaaaaggtct gaacttatca ggaggacaac gacaaagaat
     9661 tgctattgcg agaatgtttc tgaagaatcc aaatataatc tttttggatg aagcaactgc
     9721 aagtcttgac agtcattctg aacgaattgt gaacgaagca atgaagaagc tcatgaagga
     9781 tagaaccgct attataatag cacataggtt atccaccatt ataaacgctg acaatatcat
     9841 ttttatggaa aacggtgaga tcacaggtca agggaatcat tgggagttaa agcatagtca
     9901 taaattgtat catcaattct gtgagcagca gtttaaagaa gatagtaccg atccattagt
     9961 attaaccaat taagagcggc ttaagagagg cgaaaacaaa atggacaaaa aattagttta
    10021 tttccaacac atgagtgaag attcaaaata ctatatagag aaaagcccaa atgcagagac
    10081 tgatccatat gaagtacata atataccaaa ttactatact gttagtacag aatacaaatc
    10141 accatggaag ttttataata atccaaatca tcccctcaaa gaacaaggct ggaaaataca
    10201 cgtaagtgca acaatgaata atgctcagga tatattagaa gttgtgagtc aaattatatt
    10261 taaacatcag ataccattta aacatattaa agataaacaa tctctattta atatgaattc
    10321 gaagcatggt aatcggactt catctggaaa atttatcgct atctatcctt cctctaataa
    10381 catgttcttc aggttattga atgaacttta tgaagaatta aaacattatg agaatggacc
    10441 atacatacta aatgataaat cgtggaagga cagcaatata tattaccgat atggtgcgtt
    10501 taagaatatt tacaatgaaa gaggagaact ttgtattaaa gacgaaaatg gaaacctaat
    10561 tccggataat agacagccgt attataaaat acctgaattc gtaagtgatt ttgatcagta
    10621 tttagatacc aagaataact tattagatac tcaagatgta agtaatttta atgattatga
    10681 gttccaagga gttcttaggt ttaataatgg tggcggtata tatactggaa taaggaaatc
    10741 ggatggaaaa aaagtagtaa tcaaagaagg aagacctaaa gtagggttag atggtcaatt
    10801 taatgatgcg attgatagat tgaatataga atacgaagca ttaaataaac ttacagatgt
    10861 tgaaggtgtt gttaatgtac ttgattactt taaagcatgg aaacatgtat ttttagttga
    10921 agagtttgta gaaggtgtaa ctcttcaaac ctggtgtgca atcaattatc cgttcaacgt
    10981 tgaaaatgat aaaaatgaat acattagtaa ggtgaaaaaa ataattaata gtttggtcaa
    11041 aacaattaaa caagtgcata gtaaagatgt tggtatggga gatttacaac cccaaaatat
    11101 aatgataacc cccgaatcaa atgttaagat tattgatttt gaggctgcta gtactctctc
    11161 tgaagaaaac ggagcgttgc aaacaattgg ctacacgaat aagaaaaata agaatcataa
    11221 agagcgtgat tggtatgcac taaagaaagt tttaagattt tgtattctgc caataggtcc
    11281 ggttgctgat atagaagaaa ccattaaaaa gaaacatgat atgtggatag aggacgagtt
    11341 tggcaaagat gtctatcaat atgttgtaaa tatagaaaat ctatgtgaca aatacttatc
    11401 tgacaccaaa gaaaagatat tcaagaatag ttatgacagt aaaatacaaa aagaaatgga
    11461 catgtcaaaa gtaataaaag gattgagaaa cagtatagag agtaatattt tgcccaacag
    11521 ttcgctaatt catggcgatg tacggcaatt tgtaatgcca tctggaaagt taaatgtact
    11581 aactggggga actggagctg cattggcatt gtacagatct ggaaacgtca gcaaggaagt
    11641 ttgggattgg attgaaaatg ttttacttga aaaattgaat gttcttaatg atgatgttgg
    11701 gttatttaca ggacgagctg gtatcgcagc aacattgtat gaattgggat acatagagca
    11761 agctatggac ttattcaata atctgtcata tgaagatatg aaagatattt cattaaggtc
    11821 aggattgtcg ggaataggtc tttcattaat tagcttatac atggaagaaa ataatgatga
    11881 ttttttggtt acttctgaaa aaattgctga tcagatagaa aataggatta ttgaagatga
    11941 taaattatca gtgactgatt ttgcagcagt acctataggt ttgattgatg gttggtcagg
    12001 gatatcttta ttctatgcgg cattatattc agttactaag aatgaaaaat attatttaaa
    12061 atcaaaagaa tatattgagc gagatttaaa acattgtaag gtagatgaag agacgaatac
    12121 tttgcaaaca tatgatgatc aaaaccctcg attattaccc tatttatctg ggggatcaat
    12181 cggaatagga attgctattt ggtatttaaa ttatgtaaaa aataataatt tatttagaga
    12241 agaattagag caaataatca atttaaataa agtaaggatc gcatatagcg gtggattgtt
    12301 tgatgggatc ggtagtttct tgttaatccc gtcaatgact aaggaaaaaa atgaaaccag
    12361 tcagcatatt gagctggcat tgagaaaact agaattgttt cttatccgca aagatgatca
    12421 agtattattc cctggaaact tcagttttcg tttagcagat gattactact ccggcagtgc
    12481 tggcataata ttgggcataa actctatcca gttttcaaat ccgttatatt ggttgccaat
    12541 aataaaaatt gatagtttct taagaaagac aaaaaaagaa ttgttattaa acaattaaaa
    12601 ctctaacact tatattcgat gataatcatt gaagattaga attaaagcag ttaatataca
    12661 gaacttatga agggaggtga gaaaagaaaa tgaaagaggt gctggtactt caacaatttg
    12721 atgaaaaatc tgaagtggag cctacggcat ggactgttac tctaacaact atttcagtta
    12781 cattatctac ccttagtaat cattgctaat gagagagaag gataatctaa gaaagagtac
    12841 ttgaaaggag gtgaaaccaa atgaaagatg tattggaact tcaacaactg aatgaaggaa
    12901 ctgaagtaga agcttcaaaa ggcaaaggtg gcttacttac actaatcaca acgatagttg
    12961 gctcatctac tattagcaac aactgttaag atatttaaga ggagtggatg aacaaatgaa
    13021 tgaagtacta gagttgcaac aattgagtaa aggttcagaa gtagaaacag ctgggtggac
    13081 acttctaaca acactcatcg gtacatctac tattagcaat agctgtaata aataataaaa
    13141 aggaggtgaa attgaatgag agatgtattg gaacttcaac aactgaatga aggaactgaa
    13201 gtagaagctt caaaaggcaa aggcggctta cttacactaa tcacaacagt agttggcaca
    13261 tctactatta gcaacaactg cggataaaag accaaacata acaaaaaaag attttctgcg
    13321 tacttctagt gctgaagtag aaacagctgg gtgggcactt ctgacaacgc tcatcgatac
    13381 atctactatt agcaatagct gtaataaata ataaaaagga gtgaaattga atgagagatg
    13441 tattggaact tcaacaacta aatgaaggaa ctgaagtaga agcttcaaaa ggcaaaggcg
    13501 gcttacttac actaatcaca acggtagttg gcacatctac tattagcaac aactgctaat
    13561 aaaagactaa acataacaaa aaaagatttt ctgcgtattt ctagtgctga agtagaaaca
    13621 gctgggtgga cacttcttga caacactcat cgatacatct actattagca atagttgtaa
    13681 taaataataa aaaggaggat gaaattgaat gagagatgtt ttggaacttc aacaactgaa
    13741 tgaaggaact gaagtagaag cttcaaaagg caaaggcggc ttacttacac taatcacaac
    13801 ggtagttggc acatctacta ttagcaataa ctgcggataa aagaccaaac acactaaaaa
    13861 agtacgcttg gtcttcatac attatatgaa agcctaaaca ggaaaaggac cccaatcctt
    13921 ttcctgtttc taaaaaagga ataaatttag ttttcatata aattcttttc actatcccat
    13981 acttcttatt tattgtcaat ggaaaatgaa tgaagtgggt gacttagttc tttatttata
    14041 tgtaagacta aattcaaatg ttaaatttat caaatgaaga atggaggatt aattatgaat
    14101 aacgtattag cattacaaca attaaataat agtgccgagg tggaaccgca agtgggacca
    14161 acgataacaa ctattacagt aatacctaca atggttatat ccttaataag taattattgc
    14221 gacaatcatg cttcataata taatgatttt agattgacac ttggctaaaa aagtattgca
    14281 gaaaaggaaa ctgataatta aatggataaa gtaaacaaaa aacgaccgtt atataaaaga
    14341 agttggtttc aaacggtttt ggcattttta gtttcacagc tgtattttaa ttttgtagaa
    14401 ttaacgggat ggggtcctaa gtatagagaa atgaatggct tcccagcaaa catagttgaa
    14461 ctggatttct ttcaaaaata tctttcattc tatgaaaatc catggtttaa tattgtcact
    14521 gttttcttag gggttttcac tgttatacaa ataatcaccg gtataacaaa ggatattcga
    14581 aattaaagca ataacttctg atgccttatt taattatgaa agaaactttc ttattaatct
    14641 tatgaatgaa gactgcgaca cttagtcagc agtctatttt attggctctg gatcaggatt
    14701 accgaatcgt aacctttgaa agccaatcga cccttagtac atatactgta taggccagaa
    14761 aaaagcaatc tttgtcaggt tgccgcttgt tgcgttggtt atttctaaac cataagccaa
    14821 atcccaaatg atccagattg aagttcttga attcttttaa gttcgagttt attttctctt
    14881 cccatctcat cctctttact ccatgtgatt cacaagcggc aagttagggc tttttctttt
    14941 tacattctct tgagtatcag atatactacc ccaaactcaa tttgcttaat cttagttttt
    15001 ccgcaaatga tattgagata cggatatggt gcagtgttaa atattttctc ttcgataaca
    15061 ggataattat tttgaattgg taatagggag agctcatatg atattctatt tgggttggaa
    15121 tactttttat ccaaaaagtt taaaagtaag gctgctaaga aagaggaaga tcagcgctag
    15181 tattaataaa ccacaatata aataaaaaat acgtgtagat aatcatcaca cttttttcgc
    15241 tctcgaacct attataaggt taaggagttg actgtgttta tagtgacact ctattacatt
    15301 aactcaatga aggtgttcta ttagatctgt tctatttcag tttgcttttt cactttttaa
    15361 cgtgtaaaaa gtgaaatgtt caaaatttac tatcgtttga taagaaatgc tttcgcgtgc
    15421 tataagtgta aaaggaaagc atggtcagtt ttttaatttt ggaatacatg atgcatccgt
    15481 attccctaat gaaaggatat gaatttatta tgatagataa tttctggcgt gaattgccac
    15541 ggccattttt tgttctggca ccaatggaag atgtgacgga tgttgttttc cgccatgttg
    15601 tgagtgaagc aggcaggcct gatgtgtttt ttactgagtt tacaaactca gaaagctatt
    15661 gtcacccgga tggaagggat agtgtgcgcg gccgtttgac tttcacggag gatgaacagc
    15721 cgatggttgc ccacatatgg ggagacaagc ctgaaaactt tcgccaaatg agcattggga
    15781 tggcggaatt agggtttaaa ggtctggata tcaatatggg ctgtcccgta cctaatgtgg
    15841 cggggaacgg aaaggggagc ggcctgatct gccgtcctga agttgcagct gaattaatac
    15901 aagcagcgaa agcaggagga ctgccggtaa gtgtgaagac cagacttggc tacacggatg
    15961 tagacgaatg gcgcggctgg ctgacacacg tattgaagca ggatattgcc aatctttcca
    16021 ttcatcttcg taccagagcg gaaatgagta aagtagatgc gcattgggag ctgatcccgg
    16081 aaattaagaa acttcgtgac gagatagcgc cagataccct tttgacgatc aatggggaca
    16141 ttcctgaccg ggaaaccggc ttaaaacttg ccgaacaata cggtgttgac ggaattatga
    16201 tcggacgagg tatttttaca aatccattcg cctttgaaaa ggagccgaga gagcacagca
    16261 gtaaggaatt gcttgatctt ttaaggctgc atctggatct tcacgataaa tattcaaaat
    16321 tagaagcacg tccatacaaa cctcttcctc gctttttcaa gatttatctc cgcggattcc
    16381 ggggagcaag tgaattaaga aatcaatgca tgaacacaaa gtcaacagat gaagtgcgtg
    16441 cattgctcga tgactttgag agaaagtatc ttgatgggat ggagcagcag tgatataaac
    16501 aatttctcat ccggcccgga tttcgatacg aattccgggt ctttttgtgc tcagccttta
    16561 ctccgcctgc accctgatta cagaaatcac agatcagccg agaagtgacc agccccttgt
    16621 ttagtcatgc agaaataagc ggatagtggt acattgatat gaaaaacaat acaagggaga
    16681 gaaacatgaa acgactatgc atcatcccct gcggcaagaa aaaaatatgg gacatccatc
    16741 cggatacagg gccgataagg gcggaagacg cttatctcag cccgtttcat caggcgtgcg
    16801 agcgatatgc gaaagcattc ttcgatgagt gggtgatttt gtcggcgaag catggattcc
    16861 ttcgtcctga tgataccgtt cccgaaaatt acgatgttac ttttggaaca ggccatccgg
    16921 agatcatgac agcggaggag ctgcgccgcc aattttatga aaagggcttt tctaatacaa
    16981 aagagcttat catgcttggc ggaaaaaaat accgaagcgt cctaaacgcc gtcatcggag
    17041 aacatcagca tctcagctgg cctctgtcct cgtacaaagg gattggctac atgcttcaag
    17101 cgctgaaccg ggcagttgaa gaaaagcaag aactgtagca cagcaaatac atacgcaaac
    17161 ggcacgatag actgtatgca gaaggacggg gacggcagtt tcggttgtgt caaatatcaa
    17221 ttgattttct tctgaaaaca gccattcaga caaaaggtgc agaagaatga agcgattaaa
    17281 acatttccga ggaaataaat acgtcgatca ttgtcaaaga ccgggtgatg tccggtcttt
    17341 tttgtgtgcc ttaaaacgag acaggtggat cagatctaga caaaatgaga cacctgtctc
    17401 aaactgtctc acagtgtaaa aacaaaacca ttgattttac gggcttaaaa agctggcaca
    17461 ctttttgcat ttattaatgt gaaccctaaa tagaaggagg cgcacaaaaa atggaattgt
    17521 taaaacgaga aggcttgtca ttaactgagg aaaaagcgct gtggatgtac caaaagatgc
    17581 tggaaatcag gggctttgaa gacaaagttc atgaactgtt cgcacaggga gtgcttcccg
    17641 gattcgtcca tttgtatgcc ggtgaggaag cggtagctgt aggggtgtgc gctcatttac
    17701 atgatggcga cagtattaca agcacgcaca ggggacatgg ccattgtatc gccaaaggct
    17761 gtgatctgga tggcatgatg gcggaaatat tcgggaaagc gaccggactg tgtaaaggaa
    17821 agggcggttc aatgcacatt gccgatctca ataaagggat gttaggggca aatggaatcg
    17881 tcgggggcgg atttacgctc gcatgcggct cagcgctcac cgctaaatat aaacagacta
    17941 acaatgtaag cgtttgcttt tttggagacg gagcaaataa ccaaggcacc ttccatgaag
    18001 ggctgaactt agcggcagta tgggaccttc ctgtcgtatt tgttgccgaa aacaacggct
    18061 acggcgaagc cacaacattt gagtacgcgt cagcctgtga ttcaatcgct gatcgggcgg
    18121 ctgcctataa catgccgggg gtcaaggtgg acggaaaaga tattttagca gtttaccagg
    18181 cagccgagga agcgatagaa agagcaagaa acggcgaagg cccgtctttg attgaatgta
    18241 tgacttacag aaactacggc catttcgaag gagatgccca aacctataaa acaaaggatg
    18301 aaaggactga gcatattaaa gaaaaggatg cgattcaagg ctttaaaaac tatcttttaa
    18361 aagaaacaga tgccaataaa ctgtctgaca tcgaacagcg tgtcagcgaa tcgattgaaa
    18421 aagccgtctc gttcagtgaa gacagtccat atccgaaaga gtcagagctg ttgacagacg
    18481 tctacgtgtc atatgaaaaa ggaggaatgt gagatggcga gagtcataag catgtcagac
    18541 gcgatcaatg aagcaatgaa gcttgcgatg agaagagacg aaaatgtgct tttaatcggt
    18601 gaggatgtcg ccgggggagc ggctgtcgat catttacagg atgatgaagc atggggcggt
    18661 gtactggggg tcacaaaggg gctcgtacag gaattcggac gcagccgagt gctggacaca
    18721 ccgatttccg aggcgggcta catgggtgcg gctatggctg cggcatcaac cgggctgaga
    18781 ccgattgcgg agctgatgtt taatgatttt atcggcacgt gctttgacca ggtgatcaat
    18841 caaggggcga aattccgcta tatgttcggc ggaaaagcgc aagtgccgat taccgtccgc
    18901 accacatacg gagctgggtt ccgggccgct gcccagcatt cacaggcgct gtatggcctt
    18961 ttcaccagca tcccgggtct gaagacggtt gttccgtcca atccgtatga cgccaaaggc
    19021 ctgctgctgg cggcaataga agacaatgat ccggtgttct tttttgaaga caaaacgtcc
    19081 tacagcatga aaggcgaggt gccggaagga tattatacaa tcccgctcgg aaaagcggat
    19141 atcaaacgtg aaggcggcga catcacgctg tttgcaatcg gcaaacaggt caataccgcg
    19201 cttgaagcgg ccgcacagct ttctgagaaa ggcatcgagg ctgaggtgct tgatccccga
    19261 agtctgtctc ctttggatga ggaagcgatt ttcacatcgt tagaaaaaac aaaccggctg
    19321 atcatcattg acgaagccaa tccgcgctgc agcatcgcta cggatattgc ggcgattgtc
    19381 gccgacaaag gctttgattt gcttgatgcg ccgattaaac gaattacagc gccgcataca
    19441 ccggtgccgt tttcgccagt gcttgaagat caatatttgc cgacatcaga tcaaattgtc
    19501 agcgtcacgc ttgaattgct tggcgagccg gcaatgaatt aaaggaggga tatagtatgg
    19561 ctgtaaaagt agtgatgccg aaattgggaa tggcgatgaa gcaaggggaa gtatcagtct
    19621 ggaataagaa agtcggcgat caggttgaaa agggagaaag catcgccagc atcaactctg
    19681 aaaaaataga aatggaagta gaagcgcccg aaagcggtac gctccttcac attaaagtca
    19741 aagagggaga aggagtcccg ccaggaacgg ctatctgtta tatcggggaa aacggtgaaa
    19801 aggtgcagga gaaggaggcg ccggcttcag aaaatgccgg ggaaccacaa gcagaacctg
    19861 aaactattcc cgctcccaaa gccgggaaag agcgtaaaca ccgcgtgaaa atatcccctg
    19921 tggcccgaaa aatggcggag aaggcaggat tgaaaattga tacgctgaac gggacggggc
    19981 ccgggggcag gatcgtaaaa gctgatgtca taaaggcgat gaagacggaa gctgaaccgc
    20041 ggtcttcggt tcagacggca cagccggagg gaaaaccggc ctcagcgatg agaaaagtga
    20101 ttgcagatcg aatgcacaaa agcctgcaaa acagcgccca gctgacactg accatgaaag
    20161 cggacattac ggaccttgtg aaatggcaga agcagctggc cgacagtgcg aaaaagcgga
    20221 gctgtgttaa actgacggtc acgcattttg tatcccgggc cgcggtgctt gcgctgaaac
    20281 agcatcctga gctgaacagt tcttatcaag aggagcggat cattacctat ccgcatgtcc
    20341 atctcgggat ggcagtttct cttgaaaacg gtctcgtcgt gccggtgatc cgtgatgcgg
    20401 aaaagctttc attccttgag cttgcggatc aaatcagcac atctgcacgc cgggcgcggg
    20461 aaggaaatgc ttccggagat gacctacacg gatcgacttt ttctattaca aatctcgggg
    20521 gatacggaat tgaacatttt accccgatcc ttaatccgcc tgaagccggt attctcggag
    20581 tgggtgcaag ctatgaaacg ccggcgttta aaggggatga gcttgtcaaa agcaccgtgc
    20641 tgccgctgag cctcaccttt gatcacagag tatgtgacgg cgctccggct gcggacttcc
    20701 tgaaaacggt taaagcgctg cttgaagagc ctgccggatt gattttatag agaggggtga
    20761 ggagattgac actagccatt atcggaggag ggcctgccgg atatgcagct gccgtgactg
    20821 ccgcgcggag gggagcagaa gtcgttctga tagacaaagg gccgctcggg ggcacgtgtc
    20881 tcaatgaggg gtgcatcccg acaaagtcgc tgttggaaag cgcgaatgtg cttgataaaa
    20941 tcaggcacgc aaatacattc ggcatcgaac ttccgcaaaa cattacgctc aattgggccc
    21001 ggatgcaggg gcgcaaacgg caaatcgtca accggctcgt gcagggcatt caatacttaa
    21061 tgaaagcaaa taaaattaga gtgatcagcg ggactgcttc atttctctca gatcaaacat
    21121 tgctgattga aggggaagga ggcgaaaaag aaattctgga agccggacgg atattgattg
    21181 catcaggatc tgaaccggcg gagctgccgt ttgccccctt tgacggcgat tgggtgatcg
    21241 acagcaaaga tgtgctttct ttacagcaaa ttccgtcctc ccttctcatt gtcggcggag
    21301 gtgtgatcgg ctgtgagttt gcctctttat tcagccgttt taaaacgaaa gtgacgatga
    21361 ttgaatcggc tgacaggctg ctcccggcag aagacgaaga tatcgcggtc gcttttgaag
    21421 actctttacg agacagcgga gttgatattc agacgaaagc ttccttccag cggattgaca
    21481 gggaaagaaa aaccgccgtg tggacaaaag acggaaaaga aattgaggcg caggctgatc
    21541 acattctggt cgcaatcggc agaaagccgc gtttgcaaga gctgaatctg gagcaggccg
    21601 gcatccttta ttctccgcgc ggcattgaag tcaatgacca tatgcagaca aatttgccgc
    21661 atatatacgc atgcggcgat gcggccggag gcatgcagct ggcgcatgcc gcgattcatg
    21721 aaggaatcac cgccgcttcg catgccacgg gaaaggacag caaagccaat atgcgggcgg
    21781 tgccccgctg tatttataca tctccggaaa tggccgctgt cgggctgaca gaaacacagg
    21841 cgagagagaa atacggagat gtaaaaatcg gagaatgctc attttccgct aacggcaagg
    21901 cattaattaa acatcagcat ggaggcaaaa tgaaaatcat tgccgaaccg gaattcggag
    21961 aaatcgtcgg ggtatcaatg atcgggccgg acgtgacgga attgatcggg caggcggtca
    22021 tgctgatgaa cggcgaaatg acggcggata tgtcggagca ctttatcgcc gcgcatccga
    22081 ctctttcgga aacgcttcag gaagcccttc tgaatgtcac cggcctcgcg gtgcattccg
    22141 tatagccgcg ataccctttc tcaggactga gaaggggtat ttttcgttga aagcgcttta
    22201 cttttcccct acaatatatg aaaagatggt ctgaacaggg gggagcgaat acaatgaatg
    22261 tcattcggaa tgattttaaa acctggaagc gctttgtgaa agaaggcgtg ctcgatgaat
    22321 cccgtattca gaagcgggtg gccgcctcat ggcaccgctg caaaaaagct gatgtcaatc
    22381 cttatcttga aaaggggccg aatgtgatgc cggcagatca tttagaaagg caggccgaga
    22441 agcatgcgtt attcttagag gcctcggcac cgtatgcaga aaaaatgaaa acggcgatgc
    22501 gggaaatgga aatgatggtt ctcctgattg atgccgacgg cgttgtccat tcagttgacg
    22561 gccacccgcg caccattcat gaagcgaacc gcatcaat
//
