LOCUS       gnlProkkaMDEKJNPC_32   14473 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDEKJNPC_32.
ACCESSION   gnlProkkaMDEKJNPC_32
VERSION     gnlProkkaMDEKJNPC_32
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 06:01:59
            Original ID  :: gnl|Prokka|MDEKJNPC_32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 33295
            Orig. end    :: 47768
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14473
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11635]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11635
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14473
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14473
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             641..1063
                     /locus_tag="ctg32_32"
                     /transl_table=11
                     /translation="MELEVLMETKQYLHFLQELPELFSLHEFPNLRCRVTWKQKRVSYQ
                     ESPLPIEVKVVEDRKYQRWFVTFTVLMVLCFIGIITLFFSIPNLYKQDIHFLRNDTIHQ
                     EFSISNSRIDLKNVNLMNNGGKDTLVVKDKKIIIAK"
     CDS             1604..1873
                     /locus_tag="ctg32_33"
                     /transl_table=11
                     /translation="MIEMKRLSEELLEYFSNTPEEQLQKDWEAIHSKYAYGPEINQFIE
                     ECEKNALHNEIVDGIYGSHPTSRVNVESPISQDFGSDSYLPMAV"
     CDS             1893..2309
                     /locus_tag="ctg32_34"
                     /transl_table=11
                     /translation="MQQAVFSLKNYSVVKVMLDLENIPPQCIFDLKIEPSGIYFQRERQ
                     YVLNLVFKASYKKENTDFEVINIKLKAVFSFGDMVQTDTIPSYFYANSIAIIFPYVRAF
                     VSTITLQANVAPIMIPTLNVSLLERELRRNTVLK"
     CDS             2320..2883
                     /locus_tag="ctg32_35"
                     /transl_table=11
                     /translation="MNRIIYQTVEDRENPDYVEQHGPFICTNKNAWLGEGYYFWDTIIE
                     LAHWWGNLCYKDSGYIICQSACDDKLEKVFDLVGRPEHLIEMKRCSEIITKKWHKSTVY
                     VPEIIAYLKQFTQFSTLYKAIRVNPLCTLPNSYIQSSLFRFNNRNKAFIDVCPAIQFCF
                     FDKSLFTEDYLIVYPEMYCQTPVI"
     CDS             complement(2969..5002)
                     /locus_tag="ctg32_36"
                     /transl_table=11
                     /translation="MQQEDDLRALAKIMEFGRAVSIFLLVVHVYVYCYPSITAWNLNLE
                     VTDRILVNFNNTTGIFNCILWTKLLAVTLLAISCLGTHGVKGEKITWPKIYAALVAGCV
                     LFFLNWWLLDLSLPHMTSTILYVITLTAGYLGLLMAGLWMSRLYRHNLMGDVFNIENES
                     FQQETRLLENEYSVNLPTSFRFQEKQHDGWINVVNPFRATIVLGTPGSGKSYAVVNNYI
                     RQMISKGYSCYIYDYKFDDLSTIAYNTLLNNMDKYKVKPRFYVINFDDPRRSHRCNPIN
                     PEFMTDISDAYEASYTIMLNLNRTWIEKQGDFFVESPIILLAAIIWYLKIYKNGIYCSF
                     PHAVELLNKPYSDLFTILTSYPELENYLSPFMDAWKGGAQDQLQGQIASAKIPLTRMIS
                     PQLYWVMTGNDFSLDINNPKEPKLLCVGNNPDRQNIYSAALGLYNSRIVKLINKKGQLK
                     STVIIDELPTIYFRGLDNLIATARSNKVAVCLGFQDFSQLNRDYGEKESKVIQNTVGNI
                     FSGQVVGETAKTLSERFGKVLQQRQSVSINRQDVSTSISTQLDSLIPASKIANLSQGTF
                     VGAVSDNFGEKIDQKIFHAEIIVDHAKVSAEEKAYRKIPVINEFKDKDGNDIMMQQIQR
                     NYDRIKLDAQAIINEEMNRIKSDPELCKRLGLDDEKSSKKKE"
     CDS             complement(5042..6298)
                     /locus_tag="ctg32_37"
                     /transl_table=11
                     /translation="MVAKISHGASLYGALAYNHNKVATGAAGILSGNRMISDRLGLPSE
                     DMRLALLSFENYLLANRNTEKPVLHISLSPAPEDRLTDDQLAELADRYMRKMGYGDQPY
                     IAYKHADTHNAHIHIVSVCVDEQGKKISDSYEHRRSMTACRELEADFGLRNGADTEKRN
                     PKAELKKVDASLGDVRHQIGNTLKAVLESYRFQTFGEYSALLSTLNIEAKQVRGEYHGV
                     PYTGIVYAATDDAGKVVSPPFKSSRFGKRFGNEQLEKRMLLNLKALKEGKWAPSIQADI
                     AHALQQADSRQRFVELLGQKRIGVVFRENEQGRIYGVTFIDHDRREVFNGSRMGKEFSA
                     NVFNDYFRWLDGISENDRNGHTAVELWQHHRHKAGPESALEQAAGILSLETNPRDYQEE
                     AFARRMKKRKKAKRKSRGI"
     CDS             complement(6283..6705)
                     /locus_tag="ctg32_38"
                     /transl_table=11
                     /translation="MEKTTGTRTGRKPKNDPADRKYSFRLNAEENTRFERLLADSGARD
                     RTLFIKKSIFSGQIKVVRIDKATIDYYIKLTEFHKQFQAIGNNYNQVVRALKNNFGEKR
                     AMSLLYRLEKLSVELMLLCKKITALTQEYERKWLQR"
     CDS             7469..8230
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 76.8; E-value: 3.3e-23)"
                     /gene_kind="other"
                     /locus_tag="ctg32_39"
                     /transl_table=11
                     /translation="MKKEPLFVALSNQKGGVGKSTFTVLLASYFHYLKGYNVLVVDCDY
                     PQHSISTMRDWEVGTIEKNVHLQNQLVEQFGTSGRKAYSILNSTPEEARETAGRFLEKS
                     GLDYDLVLFDLPGTVNVPGVFRSVINMDYVFTPVTQERMVMRSSMAFVLAIREYMHRHK
                     DVPLRGIYMFWNRMDKRVSKDLYNSYTEIFRSLKLPAMETVIPSAERYNKDFGMKGFFF
                     RSTLFPPTPSALRGSNLDLLATEIETILKLQ"
     CDS             8239..8691
                     /locus_tag="ctg32_40"
                     /transl_table=11
                     /translation="MATKRRTDYQVDEEALKRMMAGDVTALDKMVSPAEAPETISRPAP
                     SQEKQEKNSAGSPKQQIRKSTDEASGPDEYRQRFLKERLSGSRRQTYIHDALYRTVAKL
                     LPVIAPDMSVPMFLGSVLSDHLERYQDVINEIYNQEANQNPLEWKK"
     CDS             8679..9344
                     /locus_tag="ctg32_41"
                     /transl_table=11
                     /translation="MEEIVYLSVRIGCAGYLLYKLWNQKKRIRKICGLLYTPGKKEKEE
                     EGTSCGTGPGDVMGATRFVYLDENAGTFAAPYMSQPLETGNDYLGEEEAVPENEVECGL
                     PLEEMRLLKEEQERLDEQAPGTEGITPVITSDDLLNAGDVLLNLDGAQMNEEKKRRAAV
                     TLHAIRETDMFELISSQVENKSLIEELMDQYIGNDGNVLPVKRKKNEGQPEHAWRQFL"
     CDS             9766..9960
                     /locus_tag="ctg32_42"
                     /transl_table=11
                     /translation="MGKQIAKLGIRPEDLKDKTVTSEQLEKTKGGKAAGSEECVCYCGC
                     YTDDSAFGVDFNWWSRDWD"
     CDS             10001..11635
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_43"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.1e-21, bitscore: 68.0, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKMNKFPLVKLFTVDGASCYLYDGRANMFLSLSETEKNLVCE
                     YMASYGTTEGEPCPASFPSGAAAFIARLNGNGILLPGPLEARTPSGMRGEEQLWQQWEE
                     EAIPKKLTLEMTNTCNLRCRYCPYTINEQRGQGKMHASHHLKEEDARKAISDYFHEYTR
                     IFRKVEPEHRTLFLKRNPPAVSFYGGEALLRFSLLEPLVKYVLSLPWEEHHIPAEKVVY
                     HITTNATLLTREMVEFFIRYHFTLAISFDGPPEENDKYRVFKNGQGTGTVVERALDMIR
                     EVSEEYLLNHVHIQAVLAPEYDHDKVGRYFEGRSLNGCYGGVRQFSYLEFSDYSESKKT
                     DKQLAQFNIRERIKELYEKGLSPEERYQYILRDPLISAWLRYVYAILTKVGDAPSHKAR
                     YFNSCYIGRTNLLLDTYGNLHLCERSDFSMPVGEVNSGINRTAVRQMYRDFFEKTDSPS
                     CRSCWAGRFCTLCTAALIKNGAVQEPDRSICRSLRHAQEKQIEDLLYIKEYYPEILEQM
                     ERMYFQANDITLGAFHAYVKEQQDVAP"
     CDS             11632..13809
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 285.7; E-value:
                     1.3e-86)"
                     /gene_kind="transport"
                     /locus_tag="ctg32_44"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.8e-36, bitscore:
                     115.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFRVSYQHDSMQCGAACLRMVCKHYGKEYALDFLSEQCGCMIDG
                     VSLQAIRETAEDLGFRTFAVSVGLSELQAGWCPCILHWERNHFVVLYRIHKDKYHVADP
                     AKGTVIYRKEDFLKRWAGDGEQGIALLLEPTQAFYDFSSGMEPKVPSPFRFLWRYIASY
                     KKAFASVALTLLVGSLVQLVLPLLAQMMVDKGIGHKNIPLVYLILGGQLVLVLGSAAME
                     FVRNRLLLFVGMHVNISLITDFFAKLFRLPISFFETRTTGDLLQRIVDHRRVQDFLTGQ
                     VLSVLFSVMVLCIFMGVLFSYNSFLFLVFLAGSIGYGLWTMCFLHKRKLFDYMIFEKQS
                     ASNNKVYQLLTFMQEIKLQGGEGRRAGEWEALQKELLDIQMRSLSLQQFQQTGGIFISQ
                     SKNLVVTVIAAVAVIEGEMTLGMLLAVQFIIGQLNIPIEQLMQFLYNFQNVRLSIERIS
                     AIHGKAEERTGKEIPEQPEISRKDIRIEHLDFKYNLHGKAKVLDDITLTIPAQRTTAIV
                     GASGSGKTTLVKLLLGYFAPTSGNIFLGDTPLQDYDMTSWRHSCGVVLQDSHVFSESLA
                     RNIAVEDKHIDRTRLRTAARQANLEEFIEKLPLKYQTMVGAEGVGLSRGQEQRIFIARA
                     LYKDPSFVFLDEATNSLDANNERIITGNLLDFCKGRTVLIVAHRLSTIRHADKIVVLHK
                     GRIVEEGTHDELCARHGHYYELINNQLIAMG"
     CDS             complement(14069..14308)
                     /locus_tag="ctg32_45"
                     /transl_table=11
                     /translation="MERFHKILIGHGLNAMNVGINHIRIFLDGKKLFDYYPLRMKLFDY
                     HNWYQLTYPSFLEGVDKWETELDGIIKKLMISLQ"
ORIGIN
        1 tttacatatc ggtactattc aagagtttaa gaaaaaatat cctgaaatta ttaatttatt
       61 gcttcaagat gatagcattc aattttggat ttatactcct tggagtaaag ataatggcaa
      121 tcatttcatt ttacctattg agcagaaata aaatatagtt atggatcgag gaatattatt
      181 aaatcagttt aatttatctg tcgttttttt tcttcgtatt gaaagtgatt ataattatac
      241 gagagattat gtggaaaacg tagctcggaa cttcacccaa aagtatccca gctaccttat
      301 ccataagaaa agcgaagaca agataagagc ctttctaact gatacagtca aagttaaagt
      361 ggaaactttt gccgacgcag agacaaagaa cgtaaccgtg accgaagtac gtgagatagc
      421 ggacttgata gcagaatatg agggcatgga aggagaacga aatagttctt catctttcgg
      481 caatcatcct acggatgctc cctctttggg tagtaccgga gtggaacttg ccatgagcat
      541 ggataatggg gcttcggata tccgtcccat caatgtagcc aaacctacag gtgcatcggg
      601 aaaacccaag ataatgaaac gaagtgttat tcgtgtaacc atggagttgg aagtgttgat
      661 ggaaaccaaa caatacctgc atttcttgca ggaactgcca gagttgttca gcctgcatga
      721 atttccgaac ctacgttgca gagtaacatg gaaacagaaa cgggtgagct atcaggaatc
      781 tccattgcct attgaagtga aggttgtgga agaccgtaaa tatcagcggt ggtttgtgac
      841 ctttacggta ttgatggtgc tgtgtttcat cgggattatc accctgttct tttccattcc
      901 gaacctgtat aagcaggaca ttcacttttt gcggaatgat acgattcatc aggagttctc
      961 catttctaat agccggatag acttgaagaa tgttaatttg atgaataatg gtgggaagga
     1021 tacgcttgtt gttaaggata aaaagattat tatcgccaaa taaaaaatga tggaaaattt
     1081 gattcagata catagcgtaa aaaacgtgtt gtctcatagc ggatgtccag aagatctgct
     1141 ggagagttat ttgaaattct tacaaaccgg agggcaacag gtgcaaatcg tcagaggcga
     1201 agttactatg atgttccaaa aggagatgca ataccgtaaa cgaaggaatg aggagatgaa
     1261 aggaaccgtc acgtttagca ataaggacaa acataatgca ggaaactcag atatgggagt
     1321 gtttatcggg atggagttta tccaatgctg cttcggacat gggattcctg cacgggtgtt
     1381 ggatgtgcgg agggtgcgtg gagaggttgt ggaggttgtt gtggagtttg ggaagtagat
     1441 gaaagaacta acgatgctgc gtgtaatagt aatattgctt aagaactttg tcttaaatat
     1501 tgttatgata gtgaattgat tgttgctatt ggtattaaaa gtgatgactt tagccatacc
     1561 aatagaataa attactatat ttgcaatagt atatatttaa taaatgattg agatgaaacg
     1621 tttatcagaa gaacttttgg aatatttcag caacacccca gaagaacaat tacaaaaaga
     1681 ttgggaagct atacacagca agtatgctta tggacctgaa atcaatcaat ttattgaaga
     1741 atgtgaaaag aatgccttac acaatgaaat tgtagatggc atctacggaa gccatccaac
     1801 atccagagtg aatgtagaat cccctatatc ccaggatttc gggtctgatt catatttacc
     1861 tatggcagta taaaacatta aaatacatca taatgcagca agccgttttt tcactaaaaa
     1921 attactccgt agtcaaagta atgcttgact tggagaatat tccaccccaa tgtatcttcg
     1981 atttgaaaat agaaccatcc ggcatctatt ttcagagaga aagacaatat gtattaaatc
     2041 tggtattcaa ggcttcatat aagaaagaaa atactgactt tgaggttata aacatcaaac
     2101 ttaaagccgt cttttctttt ggggacatgg tacagaccga taccatccct tcttattttt
     2161 atgcgaacag cattgctatc attttccctt atgtacgtgc ttttgtaagt actataacat
     2221 tacaagcaaa cgtagctccg ataatgatac ccacactgaa tgtatcgttg ttagaacgtg
     2281 aactaaggag aaacacggtc ttaaagtaag aagccttcaa tgaacagaat catatatcag
     2341 accgttgaag acagagagaa ccctgactat gtggaacaac atgggccgtt catttgtacg
     2401 aataaaaacg catggcttgg agaaggctat tatttctggg atacaattat agagctcgcc
     2461 cattggtggg gaaatctttg ctataaggac agtgggtata taatctgcca gtcagcttgt
     2521 gatgacaaat tagaaaaggt atttgatttg gttggaagac cagagcatct gatagagatg
     2581 aaaagatgtt cggaaatcat cactaaaaag tggcacaagt caactgttta cgttcctgaa
     2641 attattgcat acctgaaaca atttacccag ttctcgactc tctacaaagc tatcagggtc
     2701 aatcctttgt gtactttgcc gaactcgtac atccaatctt ctctgttcag attcaacaac
     2761 cggaacaagg catttataga tgtatgtcct gctattcaat tttgcttttt tgataaaagc
     2821 ctgtttacgg aagattactt gattgtctat cctgaaatgt attgtcaaac ccctgtcata
     2881 taggcattat catacaaagc aataatagtg tgagggaagc ttttatatcg tttcccacac
     2941 acttcatgga gatttaaggg aagatgaatc attctttctt ctttgatgat ttttcatcat
     3001 ccaaccccaa tcgcttgcat aactccggat cacttttgat tcgattcatt tcctcattga
     3061 tgattgcctg ggcatccaat ttaatccggt catagttgcg ctgtatctgc tgcatcatga
     3121 tgtcgtttcc atccttgtcc ttgaactcgt tgatgacagg gattttccgg taagcctttt
     3181 cttccgcgct gactttggca tggtccacaa tgatttcagc atggaatatt ttctggtcta
     3241 tcttttcgcc aaaattgtcg gaaacggctc cgacaaatgt gccttgggac aggttggcaa
     3301 tcttggaagc cgggatgagc gagtcaagct gtgtgctgat ggaggtggat acatcctggc
     3361 ggttgatgga aacggactgc cgctgctgga gcactttgcc gaaacgttcg gaaagcgtct
     3421 tcgcggtttc tccaaccacc tgaccgctga aaatattgcc taccgtgttt tggatgacct
     3481 ttgactcttt ttcaccgtaa tcgcggttca actggctgaa atcctgaaag ccgagacaga
     3541 ccgccacctt gttgcttcgg gcggtagcga tgaggttgtc caatccacgg aaatagatgg
     3601 tcggcagctc gtctatgatg acagtactct tgagctgccc tttcttgttg atgagtttga
     3661 cgatgcggga attgtatagt ccaagcgccg ccgagtagat gttctgcctg tccggattgt
     3721 tgcccacgca aagcagcttg ggctctttcg ggttgtttat gtccaacgaa aaatcattac
     3781 ctgtcatcac ccaatacaac tgtggggaaa tcatgcgcgt aagggggatt tttgccgaag
     3841 cgatctggcc ctggagctgg tcctgggcgc cccctttcca ggcatccatg aagggggaaa
     3901 ggtagttttc cagctccgga tacgaggtca ggatggtaaa caaatccgaa taaggcttgt
     3961 tgagcagctc caccgcgtgc ggaaaggaac aataaatgcc gtttttgtaa atttttaaat
     4021 accagataat tgcggcaagc agaatgatgg gtgactccac gaagaaatcg ccctgctttt
     4081 caatccaggt gcgattgagg ttgagcatta tcgtgtaact cgcctcatac gcgtcggaga
     4141 tatccgtcat gaattccgga ttgatgggat tgcagcggtg tgacctgcgc ggatcgtcga
     4201 aattgatgac atagaaccgg ggcttgacct tgtacttgtc catgttgttc aacaacgtgt
     4261 tgtaagcgat ggtggagagg tcgtcgaact tgtagtcgta gatgtaacaa ctgtatcctt
     4321 tggaaatcat ctggcgtatg tagttgttta ccacggcata cgacttgccc gatccgggcg
     4381 ttcccagcac gatggtggca cggaagggat ttaccacgtt gatccatccg tcatgctgtt
     4441 tctcctgaaa gcggaagctg gtgggcaggt tgacggaata ctcgttctcc aacaaccggg
     4501 tttcctgctg gaaggattcg ttttcgatat tgaacacatc gcccatcagg ttatgcctgt
     4561 aaagccggct catccacaac cctgccatca gcaggccgag gtaacctgcg gtaagtgtta
     4621 taacgtacag tatggtgctt gtcatgtgcg gcagggacag gtcaagcagc caccagttca
     4681 gaaagaacag cacgcatccg gctaccagcg ccgcatagat tttgggccag gtgatttttt
     4741 cacccttgac tccatgtgtt cccaggcagg atattgccag taaggtcaca gccagcagct
     4801 tggtccagag gatgcagttg aaaatgccgg tcgtgttgtt gaaattcacc agaatccggt
     4861 ctgtcacctc caggttcagg ttccatgcgg tgatactcgg atagcagtac acatagacgt
     4921 gcaccaccaa aagaaaaata ctcactgccc tgccaaattc catgattttg gcaagtgccc
     4981 tcaaatcgtc ttcctgttgc atagggatgg ggataaatgg tttttgaaaa ttgtcttccg
     5041 tttaaatgcc gcgcgatttg cgtttggctt tcttcctctt tttcatacgg cgtgcgaaag
     5101 cctcctcctg gtaatccctt gggttggttt ccagggagag gatacccgcc gcctgctcga
     5161 gcgcgctttc cgggcccgcc ttgtgccggt gatgctgcca gagctccact gccgtatgtc
     5221 cgttccggtc gttttcggag atgccgtcca gccacctgaa atagtcgttg aacacgtttg
     5281 cggaaaactc cttgcccatg cgtgagccgt tgaacacctc cctgcggtcg tggtcaatga
     5341 aggtgacgcc gtagatgcgt ccctgttcat tctcccggaa caccacgccg atacgtttct
     5401 gtccgagcag ttccacaaac cgttgccgtg agtcagcctg ttgcaaggcg tgggcaatgt
     5461 ccgcctgtat ggagggagcc catttccctt ccttgagcgc cttcaggttg agaagcatcc
     5521 gtttttccag ctgttcgttg ccaaaacgtt ttccaaagcg ggagctcttg aacggagggc
     5581 tgaccacctt gccggcatca tccgtggcgg catagacaat gccggtgtaa ggcacgccgt
     5641 ggtattcccc cctgacctgt ttcgcctcga tattgagggt ggaaagcagg gcgctatact
     5701 ccccgaaggt ttggaaacgg taactttcca gcaccgcctt gagggtgttg ccgatttgat
     5761 ggcggacatc ccccagggaa gcatccactt ttttcagttc cgctttcgga ttccgtttct
     5821 ccgtgtccgc accgttgcgc aggccgaagt ccgcttccag ctcccggcag gcggtcatgg
     5881 aacggcggtg ctcgtaggag tcactgatct ttttcccttg ttcgtccaca cagacactga
     5941 cgatatggat gtgggcattg tgggtgtcgg catgtttgta ggcgatataa ggctggtctc
     6001 catagcccat cttccgcata taccggtcgg ccagttccgc cagttggtcg tcggtcagcc
     6061 tgtcttccgg tgccggggag agcgagatat gcaggacggg cttctccgtg ttgcggtttg
     6121 ccagcaggta gttctcgaaa gagagcaatg ccaggcgcat gtcttcactt ggcaatccca
     6181 gccggtcgga aatcatgcgg ttccccgaaa gaatccccgc cgccccggtc gccaccttgt
     6241 tatggttgta ggccagtgcc ccgtacaggc tggcgccatg acttatcttt gcaaccattt
     6301 ccgctcgtat tcctgggtga gtgccgtgat tttcttgcag agaagcatca gctcgacgct
     6361 cagcttctcc agcctgtaga gcagtgacat cgcccgtttc tccccgaaat tgttcttcaa
     6421 ggcacgcacc acctggttgt agttgtttcc tattgcctgg aactgcttgt ggaattcggt
     6481 cagcttgatg tagtaatcta tggtcgcctt gtcgattctc actaccttta tctgtcccga
     6541 aaagatggat ttcttgatga acagcgtgcg gtccctggct ccggaatccg ccagcagcct
     6601 ttcaaatctg gtgttctcct cggcgttcag gcggaagctg tacttgcggt ccgccgggtc
     6661 attcttgggt ttcctgcctg tccttgtccc tgttgttttc tccataatgc atgagattgt
     6721 tggtttgtac tttttttctt ttccagaatc cgcgactttg gagcggattc ccccgcccgg
     6781 gggcgggcaa gttggtcctt gtcggacaaa agactttttg tcggacaagg acacaacttg
     6841 ctctgttcgt ttgaacagag aatcctcctt cgtcggattg ctgcgcgacg ttcacggcgt
     6901 gctgtggtcc gatgaagcat gttcctctcc attgacggat tttgattttg caaaattaga
     6961 gagtgttaac tggctggtaa atagtgtttt atatgacgtt tgatgacatc tgacgacatc
     7021 tgatgtcagg ccggggaaat gttggcggaa gtctcaaaaa tagccgctac ttttggcaca
     7081 gtgcatgagg gcatacattg gaacattgtc ctgtaaggtg tattgcttgc ctgccacagg
     7141 cggtacatgg cacggatgca atatcatccc tgtaggtaca ttgccataca tgttgcacgg
     7201 tgatcctgca tggcggatta cattgcatga atgcaataca gtacgggttg cattggactc
     7261 cgtatcacat gaatgcaatg taccttatat ggcaataccc tccggtaacc ggcaatacat
     7321 tggtgcaata gggtacgcaa tgtattcatg caagcgggca ggcagtgcgt cattgccata
     7381 taccgacaga tgcgttgtca tgtaatgaaa cagaaaaaac agaaccggac agatatgaaa
     7441 ccaaattata cactctaaat tcaagcctat gaagaaggaa cctttatttg tcgctttgag
     7501 caaccagaag ggcggtgtgg gaaaatccac gttcaccgtc ttgctcgcca gttacttcca
     7561 ttacctgaag ggatataacg tgcttgtggt ggattgcgat tatccgcagc acagtatcag
     7621 caccatgcgg gactgggaag tggggaccat tgaaaagaac gtgcatttgc aaaaccagct
     7681 ggtggaacag ttcgggacaa gcgggaggaa agcctacagc atcctgaact ccactccgga
     7741 ggaagcccgg gaaactgccg gccgtttcct tgagaaatcg ggactggact atgaccttgt
     7801 cctttttgac cttcccggaa ctgtgaatgt gcccggtgtc ttccggtccg taatcaatat
     7861 ggactatgta ttcactcccg tcacacagga aagaatggtt atgcggagca gcatggcttt
     7921 tgtccttgcc atccgggaat acatgcaccg tcataaggat gtgcccttgc gtggcatcta
     7981 tatgttctgg aaccggatgg acaaacgtgt atccaaagac ctgtataaca gctacactga
     8041 aattttccgc tcgctgaaat tgccggcgat ggaaaccgtc attcccagtg cggagcgcta
     8101 caataaagac ttcgggatga agggattttt ctttcgcagc accttgttcc ctccaacccc
     8161 ttccgcattg aggggcagca atttggactt gctggcaaca gagatagaaa ccatactgaa
     8221 acttcaataa gaacaatcat ggctaccaaa agaagaacgg attaccaggt ggatgaggag
     8281 gcattgaaac gtatgatggc cggggatgta acagcattgg acaaaatggt ttctcccgct
     8341 gaggctccgg aaacaataag ccggcctgcc ccttcccagg agaagcagga gaagaactcc
     8401 gccggttctc ccaaacagca gataagaaaa tccacggatg aggcgtccgg cccggatgaa
     8461 taccggcaac ggtttctgaa agagagactg tccggttcaa gaaggcagac ctatattcac
     8521 gatgctttgt acaggactgt tgccaaatta ttgcctgtca ttgcgccgga tatgtcagtt
     8581 cccatgtttt taggcagtgt cctgtccgac cacctggaaa gatatcagga tgttatcaat
     8641 gaaatatata accaggaagc aaatcaaaac cctttggaat ggaagaaata gtttatttgt
     8701 cagtaaggat cggctgtgcc ggctacttgt tatacaagtt atggaatcag aaaaaacgga
     8761 tccgtaagat ttgcgggctg ctctataccc ccgggaaaaa ggagaaggag gaagagggaa
     8821 catcgtgcgg tacaggaccg ggtgatgtga tgggggctac ccgatttgtc tatctggacg
     8881 aaaacgcggg tacgtttgcc gccccctaca tgagccagcc gttggaaacc gggaacgatt
     8941 atctcggaga ggaagaggcg gtgccggaga atgaggtgga gtgcgggctc cctctggaag
     9001 agatgagact gttgaaagag gaacaggaaa ggctggacga acaggctccc ggcacggaag
     9061 gtatcactcc ggtaatcacg tccgatgacc tgctcaatgc cggcgatgtg ctgcttaatc
     9121 tggatggcgc ccaaatgaac gaggagaaaa aacgccgggc tgccgtcacc ttgcatgcca
     9181 tccgggaaac ggatatgttt gaactgattt catcccaggt ggagaataaa agcctgattg
     9241 aggagctgat ggaccaatat atcggcaatg atggaaatgt attgccggtg aaaagaaaga
     9301 aaaatgaagg acagccggaa catgcctgga gacagtttct ctgaacccgg cggcagtcag
     9361 tccgaaacga aaggaagagg ctttggaagc acctgccttg taccgctatc atggttgcct
     9421 gttcccggtt cctttgtcat gcctggttct ttaaatgtcc atatattttg attgttcggt
     9481 tggtgacgga ttcctttccg gaatcatata gaagctaaga tgttaatgaa aaataattca
     9541 ttacgtttat cctatttttt tttaagaaaa atattgtgtt cttgaatgga atctgtatat
     9601 ttgagacaga ttgcaaaaat gaattataga gccgtgattt atcaggaaaa acgaatgtca
     9661 gtatcgcggc tatgggattt gaataaccgg taagctatat cagcattgca atattttaaa
     9721 ggagtgaaat gttgcaagta tgaactaact ccaattttaa aggctatggg aaaacagatt
     9781 gccaaactag gtatccgtcc ggaagacctg aaagacaaga cggtcacttc ggaacagttg
     9841 gaaaagacga aaggcgggaa agccgccggg tctgaagagt gtgtatgcta ctgcggttgc
     9901 tataccgatg actccgcttt cggtgtagat ttcaactggt ggtcaagaga ctgggattga
     9961 ttcctgcatt gtacgatgct ttgtaaacag attagccact atggaaaaac aaaaaatgaa
    10021 taagtttccc ctggtcaaat tgttcacagt tgacggggcg tcctgttatt tatatgacgg
    10081 cagagcgaac atgttcctgt cgctgtccga gactgagaag aaccttgtct gtgaatacat
    10141 ggcgtcgtat ggaactactg aaggagagcc ttgcccggcc tccttccctt ccggtgccgc
    10201 cgctttcatc gcccgtctta acggaaacgg catcctgctt ccgggtcccc tggaagcgag
    10261 gacaccttcc ggaatgcgtg gtgaggaaca gttatggcaa caatgggagg aggaagccat
    10321 tcccaaaaaa ctgacactag agatgaccaa tacctgcaat ctgcgttgca ggtattgccc
    10381 ctatacaatc aacgagcaac gcggacaagg aaaaatgcac gcctcccatc acttgaaaga
    10441 ggaggatgcg cggaaagcca tttcggatta tttccatgaa tacacacgta ttttccgcaa
    10501 ggtggaaccg gaacacagga cactgttcct gaaacggaat cctcccgccg tcagtttcta
    10561 cggcggagag gcgcttctgc gtttttccct gctggaaccg ttggtgaaat atgtgctctc
    10621 gcttccttgg gaggaacacc atatacctgc ggagaaggtc gtataccaca taacgaccaa
    10681 tgccacgctg ctgacacggg agatggtgga attctttata cggtatcatt tcactctcgc
    10741 catcagcttc gacggtccgc cggaggagaa tgacaagtac cgcgtgttca aaaacgggca
    10801 gggtacagga acggtggtgg agcgtgccct tgacatgatc cgtgaggttt cggaagagta
    10861 cctgctgaac catgtacaca tacaggccgt gctggctccc gaatacgacc atgacaaagt
    10921 cggcagatac tttgaggggc gtagcctgaa cggttgttat ggcggggtcc gtcagttttc
    10981 ctacctggaa ttcagtgatt acagtgaaag caagaagacg gacaagcaac tggcgcagtt
    11041 caatatccgg gagcggatca aggaacttta tgaaaagggc ctctctccgg aggaacggta
    11101 ccagtatatt cttcgtgacc ccctgatcag cgcatggctg cggtatgtgt acgccattct
    11161 gaccaaggtc ggtgacgcac cctcacacaa agccagatat ttcaattcat gctatatcgg
    11221 gcgtaccaat ctgttgcttg acacatacgg caacctgcat ctctgcgaac ggtcggattt
    11281 ctccatgcct gtcggtgagg tgaactcggg catcaaccgt accgccgtcc ggcaaatgta
    11341 ccgtgatttt tttgagaaga cagacagccc gtcctgccgt tcctgctggg ccggccgctt
    11401 ctgtaccctc tgcaccgccg cgcttatcaa gaacggtgcg gttcaggaac ctgaccgttc
    11461 catttgcagg agcttgcggc acgcacagga gaaacagata gaggacttgc tgtatatcaa
    11521 ggagtattat ccggaaattc tggaacagat ggaacgtatg tatttccagg cgaatgacat
    11581 aacgctcggc gctttccatg cctacgtcaa ggaacaacaa gacgtcgccc catgaggttc
    11641 agggtgtcct accagcatga ctccatgcag tgcggtgcgg cgtgtctccg tatggtctgc
    11701 aagcattacg gaaaggaata tgcccttgac tttctttccg agcaatgcgg ctgcatgatt
    11761 gacggggttt ccttgcaggc cattcgcgag acggcggagg acctgggatt ccggacattc
    11821 gccgtatcgg tcggtctgtc cgaattgcag gccggatggt gtccctgtat ccttcattgg
    11881 gagcgtaatc actttgtcgt cctgtacagg attcataagg ataagtatca tgttgccgat
    11941 ccggccaaag ggacggtcat ataccggaaa gaagatttcc tgaagcgttg ggcgggagac
    12001 ggggaacagg gaatcgcctt gttacttgaa cccacacagg ctttttatga cttctcttcg
    12061 ggcatggaac caaaagtccc gtcccctttc cgttttttat ggaggtacat agcttcttat
    12121 aaaaaagcat ttgcatcggt cgccttgacc ctgcttgtcg gcagtctcgt acagctggtg
    12181 cttccgctgc ttgcgcaaat gatggtcgac aaaggtatcg gtcataaaaa tatcccgctt
    12241 gtctatctga ttctcggcgg ccagctggtg cttgtgcttg gttctgccgc catggagttt
    12301 gtccgcaacc gtcttctgct gtttgtgggg atgcatgtca atatatcatt gataaccgac
    12361 ttcttcgcca aactgttccg cctgccgatt tcattcttcg agacaaggac caccggggat
    12421 cttttgcagc gtatcgtcga tcaccgcagg gtgcaggatt ttcttaccgg acaggttctc
    12481 tccgtcttgt tctcggtaat ggtcttgtgc atattcatgg gcgtcctgtt ttcatataac
    12541 agcttcctgt tccttgtctt tctggcggga agtatcggct acggcctgtg gaccatgtgt
    12601 ttcctgcata aacgcaagtt gtttgactat atgattttcg agaaacagtc ggccagcaac
    12661 aacaaggtat accaactcct tactttcatg caggagataa agctgcaagg cggcgaggga
    12721 aggcgcgccg gggaatggga ggcgttgcaa aaggagcttc ttgacatcca gatgaggtct
    12781 ttgagcctgc aacagttcca gcagacaggc gggatattta tcagccagtc caagaacctg
    12841 gttgtgacgg tcattgccgc cgttgctgtc attgaagggg agatgacttt gggtatgctg
    12901 cttgccgtgc aattcattat cgggcagttg aacatcccga ttgaacaact gatgcagttt
    12961 ctctataatt tccagaatgt gcggctaagc atcgagcgta tcagcgcgat tcatgggaag
    13021 gcggaggaaa gaacggggaa agagataccg gaacagccgg agatttcccg aaaggatatc
    13081 cggattgaac acctggattt taaatataac ctgcatggca aagccaaggt gctggatgac
    13141 ataacgctga ccattccggc acaacgtacc accgccatcg tgggcgcaag cggaagcgga
    13201 aagaccaccc ttgtcaaact gttgctgggc tattttgctc ctacaagcgg aaatatcttc
    13261 ctgggagaca ctcccttgca ggattatgat atgacatcgt ggaggcacag ctgcggcgta
    13321 gtgctgcaag acagccatgt gttttccgaa tctctggcaa ggaatatagc agtggaggac
    13381 aagcatatag accgtacacg tctccggacc gccgcccgtc aggccaacct ggaagagttc
    13441 atagagaaac tgcccttgaa ataccagacg atggtggggg ctgaaggcgt ggggctgagc
    13501 cggggacagg aacagcgtat ctttatcgcc cgtgcgctct ataaggaccc ttcgttcgtg
    13561 tttcttgatg aggctaccaa ctcgctggat gccaacaatg aaagaatcat taccgggaat
    13621 ctgctggatt tctgcaaagg aaggacggtc ctgatagtgg cccaccggtt aagcaccatc
    13681 cgtcatgccg acaagatagt cgttctgcat aaaggcagga ttgtcgaaga gggtacccat
    13741 gacgaattgt gcgcccgtca tgggcattat tatgagttga ttaataacca gttgattgct
    13801 atggggtgaa gatagtattt tttaactttt atatgtcaaa aaagcctttt cgtcaaggtc
    13861 ttgctttttt ctttgttttc cgtattttga caatagagta taaactatat ctaaaaaaca
    13921 atctctatta tataatggaa ccagttgcat caacccttag agtgctactt ttggcttctc
    13981 attacacttg accaatgaaa aaacgctcat tcaggaatgt tgtcccaaac gagcgttgtg
    14041 ttattgtttt ctttcgtaac cggaatactt attgcagtga tatcattaat tttttgatga
    14101 ttccgtcaag ttccgtttcc catttatcca caccttcaag aaaagacgga taggttagct
    14161 ggtaccagtt gtggtaatca aacagtttca ttctcagagg atagtagtcg aagagttttt
    14221 taccatctaa gaaaatgcgg atatggttaa tccccacatt catcgcgttc agaccgtgcc
    14281 caataagaat tttatggaat ctttccattg gtgtgaagtt gcttcttttt ttcataattt
    14341 ttttattacc ctaaaatccg caactatcat ccaatacacg attaagggta gatttatgag
    14401 tcgttagtag cagctttcag taaaaagcaa cagcacaaca tcaatatgta gccaccatcc
    14461 ccttacccca cga
//
