LOCUS       c00022_gnlPro..        15434 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDEKJNPC_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:11:04
            Original ID  :: gnl|Prokka|MDEKJNPC_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15434
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15434
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[199:5434]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      200..5434
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15434
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15434
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(200..784)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_1"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.1e-63, bitscore:
                     207.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETALGMSAA
                     VAFVLTIATIVTFLIQKYVLDAFDLGYLQTITFILVIAALVQMVEIILKKVSPSLYQAL
                     GVFLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTALGFGLALTLFAGLREQMSLVS
                     VPKGMQGTPIALITAGLLAMAFMGFSGVVKI"
     CDS             complement(872..1456)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.3e-70, bitscore:
                     230.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISAIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPALYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNPVASLFDGLGMGLGFTIALTLLGAVREFLGTGKIFNLSILP
                     EEYGMLVFVLAPGAFIALGYLIALINSMKKN"
     CDS             complement(1473..2108)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="FMN_bind (E-value: 4.3e-23, bitscore:
                     75.7, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKEPIAQANAKTLSDAVSAVVPG
                     FDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVLVGFDAEGKII
                     DYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVDAITASTITSR
                     AFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPEAVDTLSAK"
     CDS             complement(2135..3127)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 4e-118, bitscore:
                     387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             complement(3134..4471)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="Fer4_10 (E-value: 3.7e-08, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 7.6e-15, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.1e-48, bitscore:
                     158.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 9.1e-29, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00071, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVAAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             complement(4532..5434)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.6; E-value:
                     8.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_6"
                     /sec_met_domain="Fer4_7 (E-value: 1.2e-11, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.8e-08, bitscore: 27.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 9.7e-08, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1e-07, bitscore: 25.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.2e-10, bitscore: 34.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00014, bitscore: 16.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRIYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKADDAA
                     PQVKVAAPKAEVETPKAEV"
     CDS             complement(5472..5891)
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MANTIKHQGIVENINGSHLQVRIIQTSACASCSVKGHCTSADTKE
                     KLVDVADANAASYQPGDRVWVTGELSMGVMAVLFAFIFPFLILIISLFVFMAIWNDELR
                     SALCSLALLVPYYYILWLNKSRMGKKFSFSVRPMN"
     CDS             complement(6122..7522)
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="MISSSVMAQNTLDTASKNSGQETTAKADTLPDIMKEYMILKLKPE
                     GMGYRLDTVSILYERYIGVLDYLNDPTTPERYIPSNPNYYRLFLPLTYYYAPMRRLSKV
                     DWHFQVPDTVPALTREMLPFDTLSFTSKDRANKLVDRTLLNTYVDCPNLVVMTEKEVMK
                     GKIFKDNIEKEVSSKPSVVKLFAQENMVGVKEEADVIIHKPNWWVTGGNGSLQITQNYI
                     SDNWYKGGESTNAVLANLQLFANYNDREKVQWENLLDAKLGFSSAPSDEFHNYLVSTDQ
                     LRLYSKLGIQAASKWYYTITTEFKTQFCNGYKANSEELVSAFFAPADWSSSIGMDYKLK
                     KQKFSLSVFMAPLTYMLRYVGNKGVNEVSFGLEEGKCVKHNFGSQIQPTLSWTIIPSIT
                     LDSRLDFQTSYEWTRIEWENTVNFVLNRYLSTKLYVHARYDDSAKPTEGDSYFQVKELL
                     SFGINYKW"
     CDS             7832..9451
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_9"
                     /sec_met_domain="GATase (E-value: 1.4e-53, bitscore: 175.4,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGKDALCVHLTYVPYLAAAGELKTKPTQHSVKELQSAGIQPDVLVLRTEHELSTTL
                     RKKVALFCNVDENAVVQSIDAPTIYEVPILMQSQGLDVTILKKMGLPVGDTPGLGPWRA
                     FLERRHKAEETAPLHIALVGKYDLQDAYKSIREALSQAGTYNDRKVSVDFVNSEKLTDE
                     NVAEALKGMAGVLIGPGFGERGVAGKFVAIKYARTHDIPTFGICLGMQCIAIEFARNVL
                     GYADANSREMDEKTPHNVIDIMEEQKSITNMGGTMRLGAYECVLQKGSKAYEAYGTEHI
                     QERHRHRYEFNNSFKDAYEAAGMKCVGINPESDLVEIVEIPALKWFVGTQFHPEYSSTV
                     LHPHPLFVAFVKAAIENENEKK"
     CDS             9483..11336
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="MDKNTITGLVLIAILLVGFSFLSRPSQEQLEAQQRYYDSIAQVQQ
                     READLKAKAEAALANESGAEASVDSTALFFDARQGTNSQVTIQNNLAEITVDTKGGRIA
                     SATLKEYMGQDKTTPVTLFSGNDASMNFLFYNKKETIQTEDYYFTAVNRTDSTVTMRLS
                     ADSNSYIDFTYRMHNDTYLIDFTIQAVNMEGKLAATNNYVDIEWSQRARQIEKGYTYEN
                     RLAELTYKITGEGTDYLSANKNDEKEVPERLDWIAFKNQFFSSVFLADADFEKTKLSSK
                     METQGSGYIKDYSAEMSTKFDPAGKEPTQLFFYFGPNHYKTLTALDKGRDEKWELNRLV
                     YLGWPLIRWINKWFTINIFDWLSSWGLSMGIVLLFMTLIVKAVVFPATWKTYMSSAKMR
                     VLKPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLIQFPILMALFMFVP
                     SAIELRQQSFLWADDLSTYDAFINFPFHIPFLGSHLSLFCLLMTVTNILNTKYMMQQQD
                     TGANPQMAAMKWMSYLMPIMFLFILNDYPSGLNYYYFISTLVSVVTTLIMRKTTNEEAL
                     LAQLEANKKDPKKMKKTGFAARLEAMQKQQEQMMKEKQNKK"
     CDS             11438..12769
                     /locus_tag="ctg22_11"
                     /transl_table=11
                     /translation="MQTKYTYKQIWLIAYPILISLLMEQLIGMTDTAFLGRVGEVELGA
                     SAIAGVFYMVIFMVAFGFSIGAQILIARRNGERQYKEIGDLFYQGIYFQVGMAAVMFLL
                     SYCFSPIILKRIVASEHIYEAATSYLHWRVFGAFFSFSAVMFRAFFLGTTQTKTLTLNS
                     IVMVLSNVVFNYILIFGKFGFPALGIAGAAIGSSLAELVSLLFFILYTRSRIDCCKYGL
                     DRIPKFRLDVLKRMLNVSFWTMIQNFFSLSTWFLFFLYVEHLGERSLAVTNIVRNVSGI
                     LFMVLMAFASTCGSLVSNLIGAGHSDCVAGTIRQHVRIAYVFVLPLALLFALFPKLILG
                     IYTDIPDLQDAAVHSLWVMCSTYLFLVPANVYFQAVSGTGNTRTALGMELATLVIYTAY
                     ITYIILILQLDVAICWTSEMVYSSFILIFCWLYIKRGNWQGRKI"
     CDS             12807..14930
                     /locus_tag="ctg22_12"
                     /transl_table=11
                     /translation="MKQVNLLLMSAAMTLASCGGTKDAGQQQDAAALIQRSDIKIEGKR
                     MTPEALWAMGRIGSVAVSPDEKQIAYTVSYYSVPQNKSNSEVFVMNADGSDNTQITHDA
                     WQEGQPTWFKDGKKLAFLCNESGSSQVWEMNPDGSGRKQLTQYEGDIEGFSFSPDGKKL
                     LFIAQVKTVKSTADKHPDLPKATGIIVTDLMYKHWDEWVTTAPHPFVADFDGNAISNVT
                     DILEGEPYESPMKPWGGIEQLAWSPSSDKVAYTCRKKTGLAYAISTNSDIYIYDLASKE
                     TKNITEENKGYDTNPQYSPDGKYIAWQSMERDGYEADLNRLFIMNLETGEKRFVSKAFE
                     SNVDAFLWNKDSQSIYFIGVWHGETQIYNIDLAGNDKLTRLTDGMYDYASLALCGDKII
                     AKRHSMSMGDEIYAVNSTRNGDAFAEAVQLTTENKQIYDQLEMGKVEARWMKTTDGKQM
                     LTWVIYPPQFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANDYIIVAPNRRGLP
                     GFGVEWNEAISGDYGGQCMKDYFTAIDEMAKEPFVDKDRLGCVGASFGGFSVYWLAGHH
                     DKRFKAFIAHDGIFNMEMQYLETEEKWFANWDMGGAYWEKNNATAQRTFANSPHLFVDK
                     WDTPILCIHGEKDFRILANQAMAAFDAAVMRGVPAELLIYPDENHWVLKPQNGVLWQRT
                     FFEWLDKWLKPAK"
ORIGIN
        1 gcatcgtggg gtaaggggat ggtggctaca tattgatgtt gtgctgttgc tttttactga
       61 aagctgctac taacgactca taaatctacc cttaatcgtg tattggatga tagttgcgga
      121 ttttaggatt aataaaaaca gaaaaagggg gataaatttt agtttatccc ccttccactt
      181 tatttccgtt ttttcttctt taaatcttca caacccccga aaagcccatg aatgccattg
      241 ccagcagtcc ggcagtaatc aaagctatcg gagtaccctg catacctttc ggtacactaa
      301 ccaggctcat ttgctcgcgc aggcctgcaa acagtgtcag tgccaagccg aaaccaagtg
      361 ccgtggagaa tgcataaacc actcccgtca gcaaatcata atctttttgg ataacaagga
      421 tagccacacc gagaatacag cagttggtag taatcaacgg caggaacacg cccaaggcct
      481 gatacagaga aggagaaact ttcttcagga taatctctac catctgcacc aatgcggcaa
      541 tcaccaggat aaaggtaata gtctgcaaat agcccaaatc aaaagcgtcg agcacatact
      601 tctgaataag gaatgtcacg atagtggcga tggtgagcac gaatgccacc gctgccgaca
      661 tgcccaatgc agtctccact ttcttggaaa ctcccaagaa cgggcaaatt cccaagaatt
      721 gcgacaatac gatgttgttt acaaagattg ccgagataaa tatcaatata tattccataa
      781 tcattaaatt aagaattaaa aactaaaaat taaaagcccg gcagtctacc gccgatacgt
      841 tctcaatttt ttcattttta atttttcatt attaattctt cttcatactg ttgattaaag
      901 caatgagata gcccaatgcg atgaatgcac ccggagcaag gacaaatacc agcatgccgt
      961 attcttcggg aaggatactc aggttgaata tcttgccggt tcccaggaac tcacgcacgg
     1021 cacccagcaa tgtcagtgca atggtaaagc ccaagcccat gcccagaccg tcgaacaagg
     1081 aagccaccgg attgtttttg gcagcaaatg cctcggcacg tcccaatacg atacagttta
     1141 caacaatcag cggaatgaac aggcccagtg tggcgtacaa tgcaggaacg taagcttgca
     1201 ttatcatctg caacagtgtc acaaatgatg ctatgactac aatgaatgaa gggatacgca
     1261 ccatatcggg aatcagattc ttgatggcag aaatcaccac attggaacat atcagcacga
     1321 acattgtagc cagtcccata cccataccgt taatggcaga ggaagtggta cccagtgtag
     1381 gacacatacc cagcaggagt acaaacgtag gattctcttt gataatcccg ttcatcataa
     1441 ctttaaaatt attcatatct tctactcctt tctcatttag cgctgagtgt atccacagct
     1501 tcgggagctg cggaatcagc aggttgttca acattctttt gagtagcgcc ggtagtgccg
     1561 tcggcagttt cctgaccggc ataggcagca taagccgcat tcactgcatt caaaaaagca
     1621 cgtgaggtga tggtagacgc tgtaatggca tctactttac caccgtcctt gctcactgtc
     1681 aatgcagctt cacccggatt catgccggtg atgtcacctt tattgccttt cttgaaccag
     1741 tcggcagcct tggaacccaa ccccggagtt tccacatgcg acaacaagga gtagtcgatg
     1801 attttgcctt cagcatcgaa accgaccaac actttcagct caccgccaaa acccatggca
     1861 acagcttcca cagcagctcc gatatattct ccgcctttgg tggcaggata tacagaatac
     1921 tgtactccgt ttacttcctg catcttcttc tcggcgatgg ggtcattgtc gaagcccgga
     1981 accaccgcac ttacggcatc gctcaaggtc tttgcattgg cctgcgcaat gggctccttc
     2041 gtcaattcgt ttacataagc cagcaacgct acggagattg cggtaacgcc cgtaagtacc
     2101 agcaacatat tcttcaagga tgattctaac tttttcattt cttcttcgct acctccccaa
     2161 agcgtttagg tttaacatag gtgttgatga gcggagtgaa cgcattcata atcagaatgg
     2221 caaacgacat accctccgga tatgcaccga acagacggat gatgacagtc agtaggccga
     2281 tgcaaacacc ataaatcagc atacctttgt ggctcatcgg agaagtcacg tagtccgtag
     2341 ccataaagac agcacccagc atcagaccac cggacaacaa ctgtacgacc ggggatacat
     2401 aaagttccgg attgaccaga tacatgatac cggagaacac gaataccgtc accagaatag
     2461 ataccggaat gtgccaggtg atgattttct tccacaacat gtagaacaaa ccaagcagca
     2521 gcgccaaggc actcacctca ccgagacatc ctccattatt acctatcaga aggtcgaaag
     2581 ctcccggaag gtcgctcagg gacatgcccg gagcaccatt gatgacacct ttcataatag
     2641 ccagcggcgt agcagctgtc gtggcatccg tataggctgt caactggcct acagccggcc
     2701 atgtcgtcat ctgcacgggg aatgaaagca acaggaacac acgtcctgcc agtgcagggt
     2761 taaagggatt gcaacccaaa cctccgaagg acatcttgcc taccccgatg gcaaacaagg
     2821 caccaaggat gataatccag atgggcaggt tggaaggcag gttaaaggcc agcaacacac
     2881 cggtaatgat ggcagaaccg tcggtaatgg ttgtggtctc ttttttcatg aggaatttgc
     2941 cgatggccca ttcaaagaac aagcaggctg ctacggaagt ggccgtaaca atcagcgcac
     3001 ccagtccgaa aaagtaaagc gaaacaagga atgccggaat caatgcgata agcacaccgt
     3061 acatattctt cttcacgctg tcaccgccgt gaacgtgggg cgaaagggat acgattaatt
     3121 tattcatact tcgttatttt ttagcttgac gtgcacggat catcgctcct accttaccct
     3181 tacccaagcg gatataatcc agcatcggac ggttggaagg acaagtgaac tggcatgaac
     3241 cgcattctat acacgacata atgtcttctt tctctactct ttcaaaatct ccgtgggccg
     3301 aaacggtagc cagcagatac ggctccaacc ccatcgggca ggctcccacg cacttagcac
     3361 aacggataca aggctgtact tcgccgcgct tggcttcctt ctcgttcata atcagaatac
     3421 cggagcttcc tttggctgtc ggtacatccg tatttaccag agctttaccc atcatcgggc
     3481 caccgccgat aatcttgccc gtatcttcgg gcagaccgcc gcaagcttca atcagctgct
     3541 tcatcggcgt accgatacgt gccaggaaat tggacggctt tgccaacgac ttaccagtca
     3601 cggtaatgac acgctcaaac agaggtttgt tcttctgtac ggcctggtaa acggcaaatg
     3661 cggtacccac attctgcacc acagctcccg tggagatagg cagcgcaccg gctgcaacct
     3721 ggcgactgat gacagcatca atcaactgct tttcaccacc ctgcggatat tgtaccttca
     3781 agggtaccac ctcgatacct gcatagctgg aagcaacctt cgtcatcagc tggatggcat
     3841 cgggcttgtt gttctcaatg ccaatgaatg ccttgttcac ctttaccgct ttcatcagaa
     3901 tggatacacc taccataatt tcttccgcat gttccagcat cagctgatgg tcggcagtca
     3961 gatacggttc gcactctacg gcgttgatga tgacacactc tgccttgaat gcaggaggag
     4021 gacacaactt gacctgcgta ggaaagcatg caccgcccag acctacgata ccggcatcag
     4081 cgattttctt cacgatttcc tcggaggtca gactgcattc cttcaccaac gtttcggaac
     4141 ggtcaatgga ttcttcccat tcatcccctt ctacgtcaat gaatatagca ggcttggcgt
     4201 aaccgctggc atcgacaatc gtgtcaatct tagcgacttt cccgctgaca gacgaatgaa
     4261 tggctgctga tacaaaaccg ccgggctcgg caatcttcgt acccactttc acaacatcac
     4321 ctttggcaac gataggcttg gcaggagcac cgatgtgctg tcccagcaag atagcggcct
     4381 tggccggaat ctctgccttg atgataggct gatgtgctga aagtttattt tcgtgtggat
     4441 ggactccacc aattgaaaat gtcttcaaca tacaattctg tatttttagt cgtttattta
     4501 ctttattaat tcatacctca acttgggaag tctaaacctc tgctttggga gtctcaacct
     4561 cagctttagg agctgcaacc tttacttggg gagctgcatc gtcagccttc ggtttgcgcg
     4621 gcgggaagtt gagggcaatg attgtgtttt gcggacaagc ttcctcgcac ttgcgacagg
     4681 atttgcactt attggggtca atgtaagcca gattgttttc cagcgtgata gcctcgaacg
     4741 gacaaacctt cacacacttg ccgcaaccga tacatgccac ggtacaagcc ttgcgtgcta
     4801 cggccccctt gtccttgttt acacactgta cgtaaatacg acgtgatttc ttgccttgag
     4861 gacggatttc aataatagat ttcggacaag ccttggcaca agctccacaa gccgtacact
     4921 tttcctcatc cacttcggga agtccggtct ccggattcat gtggatagca tcgaactggc
     4981 aggcagccac acagtcgccg catcccagac agccataact acaacccgtt tcaccaccat
     5041 agagagaagc cgcaatggca caactcttgg cgccatcgta ttggttcaca cgaggacggt
     5101 tggcacaagt tccattacat ctcaccaccg caaccatagg ttcggcagca gcggcatcca
     5161 agcccagaat ctcggcaatc tttgtcatga cgggctgtcc acccaccgga caaagtttac
     5221 catccagcga acctgccttt acgcaagcat ctgcaaatcc gctacaaccg gggtaaccac
     5281 atccaccgca atttgcctgg ggaagcacct ctgctacctg ggcaatccgc ggatcttcat
     5341 acacggcgaa tttcttggaa gccacgtaaa gaatagcggc cgataccagc gctataactc
     5401 ccaatgaaat cactgcaatc agaattacat tcataaatta gttgtttatt aattatttgt
     5461 tttattatta gttagttcat cggtcgtacg gagaatgaga acttcttacc catccgcgac
     5521 ttgttcagcc acaatatata ataataaggt acaagaagtg ctagcgaaca aagcgcggaa
     5581 cgcagctcgt cattccagat agccataaag acaaacagtg agattatcag aataaggaaa
     5641 ggaaatataa aggcaaacag aactgccatc actcccattg aaagttcgcc cgtcacccat
     5701 acacggtcgc cgggctggta ggatgcggca ttggcatcgg ccacatcgac aagtttctct
     5761 ttcgtatccg cagaggtaca atgccccttg acactacacg aagcgcacgc tgaagtctgg
     5821 atgattctca cttggagatg agaaccgttt atgttttcca caataccttg atgttttata
     5881 gtattcgcca ttttgcaaag tgtgcattac aaatcgcggc aaatttacgc attatttgtg
     5941 aactgcaaac ctttcctatg cattttctgt gttcgtaaac gtgctttttc tatgttttta
     6001 tgttttttca cctgccacag actacaaaaa gacaaaaaac agacggtctg tcaaggaaaa
     6061 acagaccgtc tgactaacca aaacagataa tctgttcact ccgaacagac catttgttta
     6121 tttaccattt ataattgata ccgaaactga gcaattcttt tacctgaaaa tagctgtccc
     6181 cttccgtcgg cttggcactg tcgtcatagc gggcgtgcac atagagcttg gtggaaagat
     6241 agcggttcag cacaaagttc accgtgtttt cccattcgat acgcgtccac tcataactgg
     6301 tctggaagtc caggcgggaa tccagcgtaa tggaaggaat gatggtccac gaaagtgtag
     6361 gctgtatctg cgaaccgaag ttatgcttca cgcacttgcc ctcctcaaga ccgaaactca
     6421 cttcattcac acccttattc cccacatagc gcagcatgta cgtcagcgga gccatgaaaa
     6481 cggacaagct gaatttctgc ttcttcaact tgtagtccat accgatactg ctcgaccagt
     6541 ccgccggagc aaagaaagcc gaaaccagct cttcactgtt ggccttgtag ccattgcaga
     6601 actgggtctt aaactcagtc gtgatggtat aataccactt ggacgcagcc tgaataccca
     6661 gtttactgta cagccggagt tggtcggtac ttaccagata gttatgaaac tcgtcggaag
     6721 gtgcggagct gaagcccagc ttggcatcga gcagattttc ccactgcacc ttttcacggt
     6781 cattatagtt ggcaaacagt tgcaggttgg caagcacggc gttagtgctc tcacctccct
     6841 tgtaccagtt gtcggagata tagttctggg taatctgcaa tgaaccgttt ccaccggtca
     6901 cccaccagtt gggcttgtgg ataatcacgt cggcttcctc cttcactccc accatattct
     6961 cttgtgcaaa cagtttcacg acggacggct tggaagaaac ctccttctct atattatcct
     7021 tgaatatctt ccctttcatc acctccttct cggtcattac aaccagattg ggacaatcta
     7081 catacgtgtt cagcagcgta cggtccacca gtttgttggc tcggtccttt gaggtgaaac
     7141 tcagtgtgtc gaacggcaac atctcgcgcg tcagggcagg caccgtatca ggcacctgga
     7201 aatgccagtc caccttggaa aggcgtctca tgggggcata ataataggta aggggaagga
     7261 acaacctata gtagttcgga ttggaaggta tataacgctc cggagtcgtg gggtcattca
     7321 aataatccag cactccgata tacctttcat ataatatgga aacagtatcc agcctgtacc
     7381 ccataccttc cggtttcaat ttcagaatca tgtattcttt cattatatcc ggcaaggtgt
     7441 cggctttggc agttgtttcc tgtccactgt tcttcgaggc ggtatccagc gtattctgtg
     7501 ccatcaccga cgaagaaatc atcgtagcaa ttaaccaaaa tgcaatgtgt ctattcttca
     7561 taatgcccta aagtctatgt ttcgagcgca aatttagctt aaaatgttta gaaaacatag
     7621 aaaagccata agaaaaaggc aagaaggact ttcttcgatg aaatcgtatt ttttaataat
     7681 tgtttcatcg aaactttctc tacttcctct tttttttata attttgcgct ttttaagttc
     7741 tacgtgtact gacgggagca gtgcgcaccc tgaacgacaa gccgtatagg ctcttggcat
     7801 tagattaaac aattaataaa ataatatagt tgtgggagaa acaaagtata ttttcgtcac
     7861 cggtggtgtt gcctcttcat taggtaaagg tatcatctca tcctccatcg gtaaattgct
     7921 gcaagcaaga ggttacaagg taaccatcca gaagtttgac ccgtacatca acatcgaccc
     7981 gggtacactg aacccttatg aacacggcga atgctacgtt accgtggatg gccacgaagc
     8041 cgacctcgat ttgggccatt acgaacgctt cctgggcatc cagaccacca aggccaacaa
     8101 tatcacgacc ggacgcatct acaaaagcgt catcgacaaa gagcgccggg gtgactatct
     8161 gggaaagacc atccaggtta ttccccatat tacagacgaa atcaagcgta atgtaaaact
     8221 gctgggaaac aaatacaaat tcgactttgt tattaccgag attggcggta cagtgggtga
     8281 catcgagtct ctgccctatc tggaaagcat ccgtcagctg aagtgggaac tgggaaaaga
     8341 cgccttgtgc gtacacctta cttatgtccc ctacctggca gctgccggtg agctgaagac
     8401 caagcccacc cagcactccg taaaggaact gcaaagtgcc ggtatccaac ccgatgtcct
     8461 cgtactgcgt acggagcacg agttgagcac taccctgcgc aagaaggtgg ctctgttctg
     8521 caatgtggac gagaatgccg tggtgcagag catcgacgcg cctaccatct acgaggtgcc
     8581 catcttgatg cagagccaag gactggacgt taccattttg aagaaaatgg gacttcccgt
     8641 cggtgatact ccgggactgg gaccgtggcg cgctttcctc gaacgccgtc acaaagccga
     8701 agagactgcc ccgctgcaca tcgcattggt gggcaaatat gacttgcagg atgcctacaa
     8761 gtccatccgc gaggcccttt cacaagcagg aacctacaat gaccgcaagg tatcggtaga
     8821 cttcgtgaac agtgaaaagc tgactgacga gaatgtggca gaagccctga aaggcatggc
     8881 aggcgtactt atcggtccag gcttcggcga acgcggcgtt gccggcaagt tcgtagccat
     8941 caaatatgcg cgtacgcacg acatccccac cttcggtatc tgtctgggta tgcagtgtat
     9001 cgccatcgaa tttgcccgta acgtactggg ttatgccgat gccaactcac gcgagatgga
     9061 cgaaaagaca ccgcacaatg tcatcgacat catggaagag cagaagtcca tcaccaatat
     9121 gggtggaacc atgcgtctgg gtgcctacga atgtgttctg cagaaaggca gcaaggcata
     9181 cgaggcatat ggtaccgagc atatccagga acgtcaccgt caccgctacg agttcaacaa
     9241 cagcttcaag gatgcctacg aagcagcagg tatgaagtgt gtgggtataa accccgaatc
     9301 ggacctggtg gaaattgttg agattcccgc attgaagtgg tttgtcggta cccagttcca
     9361 tcccgaatac agcagtacgg tattgcatcc gcacccactg ttcgtagcat tcgtgaaggc
     9421 cgccatcgaa aatgaaaacg aaaagaaata atttgtaata agtaatctgt aatcaacaaa
     9481 gaatggataa aaataccatc acaggtcttg ttctgatagc gatattgtta gtaggtttca
     9541 gctttctgag ccgtcccagc caggagcagt tggaagcaca gcaacgttac tacgactcca
     9601 tagcccaggt gcaacagcgc gaagccgact tgaaagccaa ggcagaagca gccctggcca
     9661 acgaaagcgg agcggaagca agcgttgact ccactgccct cttcttcgac gcccgtcaag
     9721 gaaccaactc gcaggtaacc atccagaaca acctagcaga aataaccgta gatacaaaag
     9781 gcgggcgcat agcttcggcc acgctgaagg aatacatggg acaagacaag acgacccccg
     9841 tcacactgtt tagcggcaat gacgcttcca tgaatttcct cttttacaac aagaaagaga
     9901 ctatccagac ggaagactat tatttcaccg cagtaaaccg tacggacagt accgtcacca
     9961 tgcgtttgtc ggcagacagc aacagctata tcgactttac atatcgcatg cacaatgaca
    10021 catacctgat agactttact attcaggcag tcaatatgga aggtaagctg gcggctacca
    10081 acaattatgt ggacatcgag tggtctcagc gtgcccgtca gatagagaag ggttacacct
    10141 acgagaaccg tctggctgaa ctgacttaca aaatcaccgg agagggtacc gattatctgt
    10201 ccgccaacaa gaacgacgaa aaggaagttc cggaacgcct ggactggatt gctttcaaga
    10261 accagttctt ctcttcagta tttttggcag atgccgactt tgaaaagacc aaactgagtt
    10321 ccaagatgga gactcaaggc agcggctaca tcaaggacta ttctgcggag atgagcacga
    10381 agttcgaccc tgctggcaag gaacctaccc agctgttctt ctacttcggc cccaatcact
    10441 acaagactct gaccgcactc gacaaggggc gtgacgagaa gtgggagctg aaccgtctgg
    10501 tctatctggg ctggccgctc atccgctgga taaacaaatg gttcaccatc aacatcttcg
    10561 actggttgtc cagttggggg ttgagcatgg gtatcgtact gttgttcatg acgttaatcg
    10621 taaaagctgt agtattcccc gcaacgtgga aaacctacat gtcctctgcc aagatgcgcg
    10681 tactgaaacc gaaaatcgac gagataaaca agaagtaccc caagcaggaa gatgccatga
    10741 agaagcagca ggaagtgatg ggcctctaca gccagtacgg agtcagtccg atgggcggat
    10801 gtctgccgat gctgatacag ttccctatct tgatggcctt gttcatgttc gtgccgagtg
    10861 ccattgaact ccgccagcag agcttcttgt gggcagacga cctttccact tacgatgcgt
    10921 tcatcaactt cccgttccat atcccgttcc tgggaagcca cctcagcttg ttctgcctgc
    10981 tgatgacggt taccaacata ttgaacacga agtacatgat gcagcaacag gatacgggtg
    11041 ccaatccgca gatggctgcc atgaagtgga tgtcatacct gatgcctatc atgttcctct
    11101 tcatattgaa cgactatcct tcgggattga actattacta cttcatctct acgttagtca
    11161 gtgtggtaac aacgctcatc atgcgcaaga caaccaatga ggaagccctt cttgctcagt
    11221 tggaagccaa caagaaagac ccgaagaaga tgaagaaaac cggtttcgcc gctcgtctgg
    11281 aagccatgca gaaacagcag gaacagatga tgaaagaaaa acagaacaaa aagtagtaag
    11341 actaccgttc aaaatattct tttgcagaaa gccggacaat gacatttgcc cggctttctt
    11401 atccttacgc caatgaaaaa atcacagact ctaaattatg cagactaaat acacctacaa
    11461 acaaatctgg cttatagcct accccatcct aatcagcctc cttatggagc aactgatagg
    11521 tatgacggac accgccttcc tcggacgtgt gggcgaagtc gagctgggag catctgccat
    11581 cgccggtgtc ttctatatgg tcatcttcat ggttgccttc ggtttcagca tcggggcaca
    11641 gatactcatt gcccggcgca acggcgaacg gcagtataag gaaatcggtg acttgttcta
    11701 tcagggcatc tatttccaag tcgggatggc ggcagtcatg ttcctgctat cttattgctt
    11761 ctcgccgatt atcctgaaac gcatcgtagc ctcggaacat atctacgaag cagccaccag
    11821 ctacctgcac tggcgtgtat tcggtgcctt cttctcgttc agcgcagtca tgttccgtgc
    11881 ctttttcttg ggaaccaccc agaccaagac actgacactg aactccatcg tcatggtgtt
    11941 gagcaatgtc gtattcaact atatcctgat tttcggtaaa ttcggttttc ctgcactcgg
    12001 cattgccgga gccgccatcg gctcctcatt ggccgagctg gtttcgctgt tattcttcat
    12061 cctctatacc cgtagccgta tcgactgctg caagtacggg ctggaccgta ttccgaagtt
    12121 ccggctggac gtattgaaac ggatgctgaa cgtctctttc tggaccatga tacagaattt
    12181 cttctccctc tccacctggt tcttgttctt cctttatgtg gagcatctgg gagagcgctc
    12241 gctggcagtg actaacattg tccgcaatgt gtccggcata ttgttcatgg tactcatggc
    12301 atttgcctct acctgcggtt cattggtcag caacctcatc ggtgcaggcc actccgattg
    12361 cgtggcaggc actatccggc agcacgtacg catagcctac gttttcgtac ttccgctggc
    12421 attgcttttc gcgctgttcc ccaagctgat tttgggaatt tataccgaca tacccgacct
    12481 gcaggacgct gccgtgcatt cgctttgggt gatgtgctcc acctatctgt tcctggttcc
    12541 tgccaatgtc tatttccagg cagtttccgg aaccggcaat acgcgtactg cattgggcat
    12601 ggagctggca acgctggtca tctacacagc ctatatcacc tacattattc tgattctgca
    12661 actcgacgtg gccatctgct ggacctcgga aatggtttat tccagcttta ttctcatttt
    12721 ctgctggcta tatatcaaac gtgggaattg gcaaggaagg aaaatttagt atctttgcat
    12781 tgaaataacc gaaacaaaaa acatatatga aacaagtaaa tctactactt atgtcagcag
    12841 ccatgacatt ggcctcctgc ggaggaacaa aagatgccgg acagcagcag gacgcagcag
    12901 cgctcatcca gcggtcggac atcaagattg aaggaaagcg tatgacaccc gaggcactct
    12961 gggcgatggg acgcatcggc agtgtggccg tatcccccga cgaaaagcag attgcctaca
    13021 cggtatctta ttacagcgtg ccccagaaca agagtaacag cgaagtcttc gtcatgaatg
    13081 ccgacggtag tgacaatacc cagataacgc atgacgcctg gcaagaagga cagcccacgt
    13141 ggtttaagga cggcaagaag cttgccttcc tttgcaacga aagcggcagc agccaggtat
    13201 gggaaatgaa tcccgacggc agcggacgca agcagctgac ccaatacgag ggagacatcg
    13261 aagggttctc tttctcgccc gacggcaaga aactcctttt cattgcccag gtaaagaccg
    13321 taaagagtac ggcagacaaa catccggacc ttcctaaagc caccggcatc atcgttaccg
    13381 acctgatgta caagcattgg gacgaatggg tgactactgc tccccatcca ttcgttgccg
    13441 atttcgacgg caatgccatc agcaatgtca ccgatatcct tgagggagag ccatacgaaa
    13501 gcccgatgaa gccctggggc ggtatcgagc agctggcatg gagcccgtct tctgataagg
    13561 tggcctatac atgccgtaag aaaaccggac tggcgtatgc catttccacc aactccgaca
    13621 tttatatcta cgaccttgcc tccaaggaaa ccaaaaacat cacggaagaa aacaagggat
    13681 atgatacgaa tccccaatac tctcccgacg gcaaatacat cgcctggcag agcatggagc
    13741 gtgacggcta cgaagccgac ttgaaccgct tgtttatcat gaacctcgag accggcgaga
    13801 aacgttttgt aagcaaggca ttcgaatcga acgtggacgc cttcttgtgg aacaaagatt
    13861 cccaaagcat ctacttcatc ggtgtatggc atggcgagac acagatttac aacatcgacc
    13921 ttgccggaaa cgacaagctt acccggctca ccgacggcat gtacgactat gcttcgcttg
    13981 ccctttgcgg agacaagatt atcgccaaac gccattccat gagcatgggc gacgaaatct
    14041 atgccgtaaa cagtacacgc aacggcgacg cttttgcaga agcagtgcaa ctgaccacag
    14101 aaaacaagca gatttacgac cagctggaaa tgggtaaggt ggaagcccgc tggatgaaga
    14161 ccaccgacgg caagcagatg ctgacctggg tgatttatcc tccgcagttc gaccctaaca
    14221 agaagtaccc caccctcctc ttctgtgaag gcggtcctca gagtcccgtc agccagttct
    14281 ggagctaccg ttggaatttc cagattatgg cagcaaacga ctatatcatc gtagctccca
    14341 accgccgtgg tcttccgggc ttcggtgtag agtggaacga agccatcagc ggtgattatg
    14401 gcggccagtg catgaaggac tacttcactg ccattgacga aatggcgaaa gaacctttcg
    14461 tcgacaaaga ccgcctgggt tgcgtaggtg ccagcttcgg aggtttctcc gtatattggc
    14521 ttgccggaca ccatgacaaa cgcttcaagg cattcatcgc acacgacggt atcttcaaca
    14581 tggaaatgca atatctggaa acggaagaga aatggtttgc caactgggat atgggcggcg
    14641 cttattggga aaagaacaac gctacggcac aacgcacttt tgccaactcc ccgcatctct
    14701 tcgtcgacaa atgggacacc cctatcctct gcatccacgg agagaaggac ttccgcattc
    14761 ttgccaacca ggcaatggcc gccttcgatg cagccgtgat gcgtggcgtt cctgccgaac
    14821 tgcttatcta tccggacgaa aaccactggg tactgaaacc tcagaatggc gtgctgtggc
    14881 aacgtacctt ctttgaatgg ctggacaaat ggttgaagcc ggctaagtaa agcccctcaa
    14941 aaacgataaa aacaaatagt cccggattct tgacaaagaa tccgggacta tttgttttta
    15001 ttgtacaccg cccgattcat tttttatgac tataatttga aagtattagg tgtaatacgt
    15061 accttgatag aagtccaaga aaaaatcaaa tctcatcccg atttaaagaa acgttacttt
    15121 cttaagcctg atgaagttat tttattggca gacggaacaa aaattgttgt caacaaccag
    15181 tggggaacat tatttccaag atttcttgaa gcagcaaaga aactgtacca agtaaccaat
    15241 gattcggaaa gcaatactcc aatatcccga ttaaagatta cttttggtaa tgggaaagta
    15301 attcaagaga tatgtcttga aaaatacttt ttcatgaaga gtacgtatat tacgctcaat
    15361 agtaagatac accctatcaa gaagatatag ccatactgtt ggtaataaat atatcctact
    15421 attataaaag tctg
//
