LOCUS       gnlProkkaCLKCHHHA_180  13892 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CLKCHHHA_180.
ACCESSION   gnlProkkaCLKCHHHA_180
VERSION     gnlProkkaCLKCHHHA_180
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 06:39:17
            Original ID  :: gnl|Prokka|CLKCHHHA_180
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 256
            Orig. end    :: 14148
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13892
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11620]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11620
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13892
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13892
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             146..1048
                     /locus_tag="ctg174_2"
                     /transl_table=11
                     /translation="MDRGILLNQFNLSVVFFLRIESDYNYTRDYVENVARNFTQKYPSY
                     LIHKKSEDKIRAFLTDTVKVKVETFADAETKNVTVTEVREIADLIAEYEGMEGERNSSS
                     SFGNHPTDAPSLGSTGVELAMSMDNGASDIRPINVAKPTGASGKPKIMKRSVIRVTMEL
                     EVLMETKQYLHFLQELPELFSLHEFPNLRCRVTWKQKRVSYQESPLPIEVKVVEDRKYQ
                     RWFVTFTVLMVLCFIGIITLFFSIPNLYKQDIHFLRNDTIHQEFSISNSRIDLKNVNLM
                     NNGGKDTLVVKDKKIIIAK"
     CDS             1055..1423
                     /locus_tag="ctg174_3"
                     /transl_table=11
                     /translation="MENLIQIHSVKNVLSHSGCPEDLLESYLKFLQTGGQQVQIVRGEV
                     TMMFQKEMQYRKRRNEEMKGTVTFSNKDKHNAGNSDMGVFIGMEFIQCCFGHGIPARVL
                     DVRRVRGEVVEVVVEFGK"
     CDS             1598..1858
                     /locus_tag="ctg174_4"
                     /transl_table=11
                     /translation="MKRLSEELLEYFSNTPEEQLQKDWEAIHSKYAYGPEINQFIEECE
                     KNALHNEIVDGIYGSHPTSRVNVESPISQDFGSDSYLPMAV"
     CDS             1878..2294
                     /locus_tag="ctg174_5"
                     /transl_table=11
                     /translation="MQQAVFSLKNYSVVKVMLDLENIPPQCIFDLKIEPSGIYFQRERQ
                     YVLNLVFKASYKKENTDFEVINIKLKAVFSFGDMVQTDTIPSYFYANSIAIIFPYVRAF
                     VSTITLQANVAPIMIPTLNVSLLERELRRNTVLK"
     CDS             2305..2868
                     /locus_tag="ctg174_6"
                     /transl_table=11
                     /translation="MNRIIYQTVEDRENPDYVEQHGPFICTNKNAWLGEGYYFWDTIIE
                     LAHWWGNLCYKDSGYIICQSACDDKLEKVFDLVGRPEHLIEMKRCSEIITKKWHKSTVY
                     VPEIIAYLKQFTQFSTLYKAIRVNPLCTLPNSYIQSSLFRFNNRNKAFIDVCPAIQFCF
                     FDKSLFTEDYLIVYPEMYCQTPVI"
     CDS             complement(2850..2957)
                     /locus_tag="ctg174_7"
                     /transl_table=11
                     /translation="MIHLPLNLHEVCGKRYKSFPHTIIALYDNAYMTGV"
     CDS             complement(2954..4987)
                     /locus_tag="ctg174_8"
                     /transl_table=11
                     /translation="MQQEDDLRALAKIMEFGRAVSIFLLVVHVYVYCYPSITAWNLNLE
                     VTDRILVNFNNTTGIFNCILWTKLLAVTLLAISCLGTHGVKGEKITWPKIYAALVAGCV
                     LFFLNWWLLDLSLPHMTSTILYVITLTAGYLGLLMAGLWMSRLYRHNLMGDVFNIENES
                     FQQETRLLENEYSVNLPTSFRFQEKQHDGWINVVNPFRATIVLGTPGSGKSYAVVNNYI
                     RQMISKGYSCYIYDYKFDDLSTIAYNTLLNNMDKYKVKPRFYVINFDDPRRSHRCNPIN
                     PEFMTDISDAYEASYTIMLNLNRTWIEKQGDFFVESPIILLAAIIWYLKIYKNGIYCSF
                     PHAVELLNKPYSDLFTILTSYPELENYLSPFMDAWKGGAQDQLQGQIASAKIPLTRMIS
                     PQLYWVMTGNDFSLDINNPKEPKLLCVGNNPDRQNIYSAALGLYNSRIVKLINKKGQLK
                     STVIIDELPTIYFRGLDNLIATARSNKVAVCLGFQDFSQLNRDYGEKESKVIQNTVGNI
                     FSGQVVGETAKTLSERFGKVLQQRQSVSINRQDVSTSISTQLDSLIPASKIANLSQGTF
                     VGAVSDNFGEKIDQKIFHAEIIVDHAKVSAEEKAYRKIPVINEFKDKDGNDIMMQQIQR
                     NYDRIKLDAQAIINEEMNRIKSDPELCKRLGLDDEKSSKKKE"
     CDS             complement(5027..6283)
                     /locus_tag="ctg174_9"
                     /transl_table=11
                     /translation="MVAKISHGASLYGALAYNHNKVATGAAGILSGNRMISDRLGLPSE
                     DMRLALLSFENYLLANRNTEKPVLHISLSPAPEDRLTDDQLAELADRYMRKMGYGDQPY
                     IAYKHADTHNAHIHIVSVCVDEQGKKISDSYEHRRSMTACRELEADFGLRNGADTEKRN
                     PKAELKKVDASLGDVRHQIGNTLKAVLESYRFQTFGEYSALLSTLNIEAKQVRGEYHGV
                     PYTGIVYAATDDAGKVVSPPFKSSRFGKRFGNEQLEKRMLLNLKALKEGKWAPSIQADI
                     AHALQQADSRQRFVELLGQKRIGVVFRENEQGRIYGVTFIDHDRREVFNGSRMGKEFSA
                     NVFNDYFRWLDGISENDRNGHTAVELWQHHRHKAGPESALEQAAGILSLETNPRDYQEE
                     AFARRMKKRKKAKRKSRGI"
     CDS             complement(6268..6690)
                     /locus_tag="ctg174_10"
                     /transl_table=11
                     /translation="MEKTTGTRTGRKPKNDPADRKYSFRLNAEENTRFERLLADSGARD
                     RTLFIKKSIFSGQIKVVRIDKATIDYYIKLTEFHKQFQAIGNNYNQVVRALKNNFGEKR
                     AMSLLYRLEKLSVELMLLCKKITALTQEYERKWLQR"
     CDS             7454..8215
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 76.8; E-value: 3.3e-23)"
                     /gene_kind="other"
                     /locus_tag="ctg174_11"
                     /transl_table=11
                     /translation="MKKEPLFVALSNQKGGVGKSTFTVLLASYFHYLKGYNVLVVDCDY
                     PQHSISTMRDWEVGTIEKNVHLQNQLVEQFGTSGRKAYSILNSTPEEARETAGRFLEKS
                     GLDYDLVLFDLPGTVNVPGVFRSVINMDYVFTPVTQERMVMRSSMAFVLAIREYMHRHK
                     DVPLRGIYMFWNRMDKRVSKDLYNSYTEIFRSLKLPAMETVIPSAERYNKDFGMKGFFF
                     RSTLFPPTPSALRGSNLDLLATEIETILKLQ"
     CDS             8224..8676
                     /locus_tag="ctg174_12"
                     /transl_table=11
                     /translation="MATKRRTDYQVDEEALKRMMAGDVTALDKMVSPAEAPETISRPAP
                     SQEKQEKNSAGSPKQQIRKSTDEASGPDEYRQRFLKERLSGSRRQTYIHDALYRTVAKL
                     LPVIAPDMSVPMFLGSVLSDHLERYQDVINEIYNQEANQNPLEWKK"
     CDS             8664..9329
                     /locus_tag="ctg174_13"
                     /transl_table=11
                     /translation="MEEIVYLSVRIGCAGYLLYKLWNQKKRIRKICGLLYTPGKKEKEE
                     EGTSCGTGPGDVMGATRFVYLDENAGTFAAPYMSQPLETGNDYLGEEEAVPENEVECGL
                     PLEEMRLLKEEQERLDEQAPGTEGITPVITSDDLLNAGDVLLNLDGAQMNEEKKRRAAV
                     TLHAIRETDMFELISSQVENKSLIEELMDQYIGNDGNVLPVKRKKNEGQPEHAWRQFL"
     CDS             9751..9945
                     /locus_tag="ctg174_14"
                     /transl_table=11
                     /translation="MGKQIAKLGIRPEDLKDKTVTSEQLEKTKGGKAAGSEECVCYCGC
                     YTDDSAFGVDFNWWSRDWD"
     CDS             10001..11620
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg174_15"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     6.1e-20, bitscore: 61.7, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKFPLVKLFTVDGASCYLYDGRANMFLSLSETEKNLVCEYMASY
                     GTTEGEPCPASFPSGAAAFIARLNGNGILLPGPLEARTPSGMRGEEQLWQQWEEEAIPK
                     KLTLEMTNTCNLRCRYCPYTINEQRGQGKMHASHHLKEEDARKAISDYFHEYTRIFRKV
                     EPEHRTLFLKRNPPAVSFYGGEALLRFSLLEPLVKYVLSLPWEEHHIPAEKVVYHITTN
                     ATLLTREMVEFFIRYHFTLAISFDGPPEENDKYRVFKNGQGTGTVVERALDMIREVSEE
                     YLLNHVHIQAVLAPEYDHDKVGRYFEGRSLNGCYGGVRQFSYLEFSDYSESKKTDKQLA
                     QFNIRERIKELYEKGLSPEERYQYILRDPLISAWLRYVYAILTKVGDAPSHKARYFNSC
                     YIGRTNLLLDTYGNLHLCERSDFSMPVGEVNSGINRTAVRQMYRDFFEKTDSPSCRSCW
                     AGRFCTLCTAALIKNGAVQEPDRSICRSLRHAQEKQIEDLLYIKEYYPEILEQMERMYF
                     QANDITLGAFHAYVKEQQDVAP"
     CDS             11617..13794
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 285.7; E-value:
                     1.3e-86)"
                     /gene_kind="transport"
                     /locus_tag="ctg174_16"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.4e-36, bitscore:
                     115.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFRVSYQHDSMQCGAACLRMVCKHYGKEYALDFLSEQCGCMIDG
                     VSLQAIRETAEDLGFRTFAVSVGLSELQAGWCPCILHWERNHFVVLYRIHKDKYHVADP
                     AKGTVIYRKEDFLKRWAGDGEQGIALLLEPTQAFYDFSSGMEPKVPSPFRFLWRYIASY
                     KKAFASVALTLLVGSLVQLVLPLLAQMMVDKGIGHKNIPLVYLILGGQLVLVLGSAAME
                     FVRNRLLLFVGMHVNISLITDFFAKLFRLPISFFETRTTGDLLQRIVDHRRVQDFLTGQ
                     VLSVLFSVMVLCIFMGVLFSYNSFLFLVFLAGSIGYGLWTMCFLHKRKLFDYMIFEKQS
                     ASNNKVYQLLTFMQEIKLQGGEGRRAGEWEALQKELLDIQMRSLSLQQFQQTGGIFISQ
                     SKNLVVTVIAAVAVIEGEMTLGMLLAVQFIIGQLNIPIEQLMQFLYNFQNVRLSIERIS
                     AIHGKAEERTGKEIPEQPEISRKDIRIEHLDFKYNLHGKAKVLDDITLTIPAQRTTAIV
                     GASGSGKTTLVKLLLGYFAPTSGNIFLGDTPLQDYDMTSWRHSCGVVLQDSHVFSESLA
                     RNIAVEDKHIDRTRLRTAARQANLEEFIEKLPLKYQTMVGAEGVGLSRGQEQRIFIARA
                     LYKDPSFVFLDEATNSLDANNERIITGNLLDFCKGRTVLIVAHRLSTIRHADKIVVLHK
                     GRIVEEGTHDELCARHGHYYELINNQLIAMG"
ORIGIN
        1 tattcaagag tttaagaaaa aatatcctga aattattaat ttattgcttc aagatgatag
       61 cattcaattt tggatttata ctccttggag taaagataat ggcaatcatt tcattttacc
      121 tattgagcag aaataaaata tagttatgga tcgaggaata ttattaaatc agtttaattt
      181 atctgtcgtt ttttttcttc gtattgaaag tgattataat tatacgagag attatgtgga
      241 aaacgtagct cggaacttca cccaaaagta tcccagctac cttatccata agaaaagcga
      301 agacaagata agagcctttc taactgatac agtcaaagtt aaagtggaaa cttttgccga
      361 cgcagagaca aagaacgtaa ccgtgaccga agtacgtgag atagcggact tgatagcaga
      421 atatgagggc atggaaggag aacgaaatag ttcttcatct ttcggcaatc atcctacgga
      481 tgctccctct ttgggtagta ccggagtgga acttgccatg agcatggata atggggcttc
      541 ggatatccgt cccatcaatg tagccaaacc tacaggtgca tcgggaaaac ccaagataat
      601 gaaacgaagt gttattcgtg taaccatgga gttggaagtg ttgatggaaa ccaaacaata
      661 cctgcatttc ttgcaggaac tgccagagtt gttcagcctg catgaatttc cgaacctacg
      721 ttgcagagta acatggaaac agaaacgggt gagctatcag gaatctccat tgcctattga
      781 agtgaaggtt gtggaagacc gtaaatatca gcggtggttt gtgaccttta cggtattgat
      841 ggtgctgtgt ttcatcggga ttatcaccct gttcttttcc attccgaacc tgtataagca
      901 ggacattcac tttttgcgga atgatacgat tcatcaggag ttctccattt ctaatagccg
      961 gatagacttg aagaatgtta atttgatgaa taatggtggg aaggatacgc ttgttgttaa
     1021 ggataaaaag attattatcg ccaaataaaa aatgatggaa aatttgattc agatacatag
     1081 cgtaaaaaac gtgttgtctc atagcggatg tccagaagat ctgctggaga gttatttgaa
     1141 attcttacaa accggagggc aacaggtgca aatcgtcaga ggcgaagtta ctatgatgtt
     1201 ccaaaaggag atgcaatacc gtaaacgaag gaatgaggag atgaaaggaa ccgtcacgtt
     1261 tagcaataag gacaaacata atgcaggaaa ctcagatatg ggagtgttta tcgggatgga
     1321 gtttatccaa tgctgcttcg gacatgggat tcctgcacgg gtgttggatg tgcggagggt
     1381 gcgtggagag gttgtggagg ttgttgtgga gtttgggaag tagatgaaag aactaacgat
     1441 gctgcgtgta atagtaatat tgcttaagaa ctttgtctta aatattgtta tgatagtgaa
     1501 ttgattgttg ctattggtat taaaagtgat gactttagcc ataccaatag aataaattac
     1561 tatatttgca atagtatata tttaataaat gattgagatg aaacgtttat cagaagaact
     1621 tttggaatat ttcagcaaca ccccagaaga acaattacaa aaagattggg aagctataca
     1681 cagcaagtat gcttatggac ctgaaatcaa tcaatttatt gaagaatgtg aaaagaatgc
     1741 cttacacaat gaaattgtag atggcatcta cggaagccat ccaacatcca gagtgaatgt
     1801 agaatcccct atatcccagg atttcgggtc tgattcatat ttacctatgg cagtataaaa
     1861 cattaaaata catcataatg cagcaagccg ttttttcact aaaaaattac tccgtagtca
     1921 aagtaatgct tgacttggag aatattccac cccaatgtat cttcgatttg aaaatagaac
     1981 catccggcat ctattttcag agagaaagac aatatgtatt aaatctggta ttcaaggctt
     2041 catataagaa agaaaatact gactttgagg ttataaacat caaacttaaa gccgtctttt
     2101 cttttgggga catggtacag accgatacca tcccttctta tttttatgcg aacagcattg
     2161 ctatcatttt cccttatgta cgtgcttttg taagtactat aacattacaa gcaaacgtag
     2221 ctccgataat gatacccaca ctgaatgtat cgttgttaga acgtgaacta aggagaaaca
     2281 cggtcttaaa gtaagaagcc ttcaatgaac agaatcatat atcagaccgt tgaagacaga
     2341 gagaaccctg actatgtgga acaacatggg ccgttcattt gtacgaataa aaacgcatgg
     2401 cttggagaag gctattattt ctgggataca attatagagc tcgcccattg gtggggaaat
     2461 ctttgctata aggacagtgg gtatataatc tgccagtcag cttgtgatga caaattagaa
     2521 aaggtatttg atttggttgg aagaccagag catctgatag agatgaaaag atgttcggaa
     2581 atcatcacta aaaagtggca caagtcaact gtttacgttc ctgaaattat tgcatacctg
     2641 aaacaattta cccagttctc gactctctac aaagctatca gggtcaatcc tttgtgtact
     2701 ttgccgaact cgtacatcca atcttctctg ttcagattca acaaccggaa caaggcattt
     2761 atagatgtat gtcctgctat tcaattttgc ttttttgata aaagcctgtt tacggaagat
     2821 tacttgattg tctatcctga aatgtattgt caaacccctg tcatataggc attatcatac
     2881 aaagcaataa tagtgtgagg gaagctttta tatcgtttcc cacacacttc atggagattt
     2941 aagggaagat gaatcattct ttcttctttg atgatttttc atcatccaac cccaatcgct
     3001 tgcataactc cggatcactt ttgattcgat tcatttcctc attgatgatt gcctgggcat
     3061 ccaatttaat ccggtcatag ttgcgctgta tctgctgcat catgatgtcg tttccatcct
     3121 tgtccttgaa ctcgttgatg acagggattt tccggtaagc cttttcttcc gcgctgactt
     3181 tggcatggtc cacaatgatt tcagcatgga atattttctg gtctatcttt tcgccaaaat
     3241 tgtcggaaac ggctccgaca aatgtgcctt gggacaggtt ggcaatcttg gaagccggga
     3301 tgagcgagtc aagctgtgtg ctgatggagg tggatacatc ctggcggttg atggaaacgg
     3361 actgccgctg ctggagcact ttgccgaaac gttcggaaag cgtcttcgcg gtttctccaa
     3421 ccacctgacc gctgaaaata ttgcctaccg tgttttggat gacctttgac tctttttcac
     3481 cgtaatcgcg gttcaactgg ctgaaatcct gaaagccgag acagaccgcc accttgttgc
     3541 ttcgggcggt agcgatgagg ttgtccaatc cacggaaata gatggtcggc agctcgtcta
     3601 tgatgacagt actcttgagc tgccctttct tgttgatgag tttgacgatg cgggaattgt
     3661 atagtccaag cgccgccgag tagatgttct gcctgtccgg attgttgccc acgcaaagca
     3721 gcttgggctc tttcgggttg tttatgtcca acgaaaaatc attacctgtc atcacccaat
     3781 acaactgtgg ggaaatcatg cgcgtaaggg ggatttttgc cgaagcgatc tggccctgga
     3841 gctggtcctg ggcgccccct ttccaggcat ccatgaaggg ggaaaggtag ttttccagct
     3901 ccggatacga ggtcaggatg gtaaacaaat ccgaataagg cttgttgagc agctccaccg
     3961 cgtgcggaaa ggaacaataa atgccgtttt tgtaaatttt taaataccag ataattgcgg
     4021 caagcagaat gatgggtgac tccacgaaga aatcgccctg cttttcaatc caggtgcgat
     4081 tgaggttgag cattatcgtg taactcgcct catacgcgtc ggagatatcc gtcatgaatt
     4141 ccggattgat gggattgcag cggtgtgacc tgcgcggatc gtcgaaattg atgacataga
     4201 accggggctt gaccttgtac ttgtccatgt tgttcaacaa cgtgttgtaa gcgatggtgg
     4261 agaggtcgtc gaacttgtag tcgtagatgt aacaactgta tcctttggaa atcatctggc
     4321 gtatgtagtt gtttaccacg gcatacgact tgcccgatcc gggcgttccc agcacgatgg
     4381 tggcacggaa gggatttacc acgttgatcc atccgtcatg ctgtttctcc tgaaagcgga
     4441 agctggtggg caggttgacg gaatactcgt tctccaacaa ccgggtttcc tgctggaagg
     4501 attcgttttc gatattgaac acatcgccca tcaggttatg cctgtaaagc cggctcatcc
     4561 acaaccctgc catcagcagg ccgaggtaac ctgcggtaag tgttataacg tacagtatgg
     4621 tgcttgtcat gtgcggcagg gacaggtcaa gcagccacca gttcagaaag aacagcacgc
     4681 atccggctac cagcgccgca tagattttgg gccaggtgat tttttcaccc ttgactccat
     4741 gtgttcccag gcaggatatt gccagtaagg tcacagccag cagcttggtc cagaggatgc
     4801 agttgaaaat gccggtcgtg ttgttgaaat tcaccagaat ccggtctgtc acctccaggt
     4861 tcaggttcca tgcggtgata ctcggatagc agtacacata gacgtgcacc accaaaagaa
     4921 aaatactcac tgccctgcca aattccatga ttttggcaag tgccctcaaa tcgtcttcct
     4981 gttgcatagg gatggggata aatggttttt gaaaattgtc ttccgtttaa atgccgcgcg
     5041 atttgcgttt ggctttcttc ctctttttca tacggcgtgc gaaagcctcc tcctggtaat
     5101 cccttgggtt ggtttccagg gagaggatac ccgccgcctg ctcgagcgcg ctttccgggc
     5161 ccgccttgtg ccggtgatgc tgccagagct ccactgccgt atgtccgttc cggtcgtttt
     5221 cggagatgcc gtccagccac ctgaaatagt cgttgaacac gtttgcggaa aactccttgc
     5281 ccatgcgtga gccgttgaac acctccctgc ggtcgtggtc aatgaaggtg acgccgtaga
     5341 tgcgtccctg ttcattctcc cggaacacca cgccgatacg tttctgtccg agcagttcca
     5401 caaaccgttg ccgtgagtca gcctgttgca aggcgtgggc aatgtccgcc tgtatggagg
     5461 gagcccattt cccttccttg agcgccttca ggttgagaag catccgtttt tccagctgtt
     5521 cgttgccaaa acgttttcca aagcgggagc tcttgaacgg agggctgacc accttgccgg
     5581 catcatccgt ggcggcatag acaatgccgg tgtaaggcac gccgtggtat tcccccctga
     5641 cctgtttcgc ctcgatattg agggtggaaa gcagggcgct atactccccg aaggtttgga
     5701 aacggtaact ttccagcacc gccttgaggg tgttgccgat ttgatggcgg acatccccca
     5761 gggaagcatc cacttttttc agttccgctt tcggattccg tttctccgtg tccgcaccgt
     5821 tgcgcaggcc gaagtccgct tccagctccc ggcaggcggt catggaacgg cggtgctcgt
     5881 aggagtcact gatctttttc ccttgttcgt ccacacagac actgacgata tggatgtggg
     5941 cattgtgggt gtcggcatgt ttgtaggcga tataaggctg gtctccatag cccatcttcc
     6001 gcatataccg gtcggccagt tccgccagtt ggtcgtcggt cagcctgtct tccggtgccg
     6061 gggagagcga gatatgcagg acgggcttct ccgtgttgcg gtttgccagc aggtagttct
     6121 cgaaagagag caatgccagg cgcatgtctt cacttggcaa tcccagccgg tcggaaatca
     6181 tgcggttccc cgaaagaatc cccgccgccc cggtcgccac cttgttatgg ttgtaggcca
     6241 gtgccccgta caggctggcg ccatgactta tctttgcaac catttccgct cgtattcctg
     6301 ggtgagtgcc gtgattttct tgcagagaag catcagctcg acgctcagct tctccagcct
     6361 gtagagcagt gacatcgccc gtttctcccc gaaattgttc ttcaaggcac gcaccacctg
     6421 gttgtagttg tttcctattg cctggaactg cttgtggaat tcggtcagct tgatgtagta
     6481 atctatggtc gccttgtcga ttctcactac ctttatctgt cccgaaaaga tggatttctt
     6541 gatgaacagc gtgcggtccc tggctccgga atccgccagc agcctttcaa atctggtgtt
     6601 ctcctcggcg ttcaggcgga agctgtactt gcggtccgcc gggtcattct tgggtttcct
     6661 gcctgtcctt gtccctgttg ttttctccat aatgcatgag attgttggtt tgtacttttt
     6721 ttcttttcca gaatccgcga ctttggagcg gattcccccg cccgggggcg ggcaagttgg
     6781 tccttgtcgg acaaaagact ttttgtcgga caaggacaca acttgctctg ttcgtttgaa
     6841 cagagaatcc tccttcgtcg gattgctgcg cgacgttcac ggcgtgctgt ggtccgatga
     6901 agcatgttcc tctccattga cggattttga ttttgcaaaa ttagagagtg ttaactggct
     6961 ggtaaatagt gttttatatg acgtttgatg acatctgacg acatctgatg tcaggccggg
     7021 gaaatgttgg cggaagtctc aaaaatagcc gctacttttg gcacagtgca tgagggcata
     7081 cattggaaca ttgtcctgta aggtgtattg cttgcctgcc acaggcggta catggcacgg
     7141 atgcaatatc atccctgtag gtacattgcc atacatgttg cacggtgatc ctgcatggcg
     7201 gattacattg catgaatgca atacagtacg ggttgcattg gactccgtat cacatgaatg
     7261 caatgtacct tatatggcaa taccctccgg taaccggcaa tacattggtg caatagggta
     7321 cgcaatgtat tcatgcaagc gggcaggcag tgcgtcattg ccatataccg acagatgcgt
     7381 tgtcatgtaa tgaaacagaa aaaacagaac cggacagata tgaaaccaaa ttatacactc
     7441 taaattcaag cctatgaaga aggaaccttt atttgtcgct ttgagcaacc agaagggcgg
     7501 tgtgggaaaa tccacgttca ccgtcttgct cgccagttac ttccattacc tgaagggata
     7561 taacgtgctt gtggtggatt gcgattatcc gcagcacagt atcagcacca tgcgggactg
     7621 ggaagtgggg accattgaaa agaacgtgca tttgcaaaac cagctggtgg aacagttcgg
     7681 gacaagcggg aggaaagcct acagcatcct gaactccact ccggaggaag cccgggaaac
     7741 tgccggccgt ttccttgaga aatcgggact ggactatgac cttgtccttt ttgaccttcc
     7801 cggaactgtg aatgtgcccg gtgtcttccg gtccgtaatc aatatggact atgtattcac
     7861 tcccgtcaca caggaaagaa tggttatgcg gagcagcatg gcttttgtcc ttgccatccg
     7921 ggaatacatg caccgtcata aggatgtgcc cttgcgtggc atctatatgt tctggaaccg
     7981 gatggacaaa cgtgtatcca aagacctgta taacagctac actgaaattt tccgctcgct
     8041 gaaattgccg gcgatggaaa ccgtcattcc cagtgcggag cgctacaata aagacttcgg
     8101 gatgaaggga tttttctttc gcagcacctt gttccctcca accccttccg cattgagggg
     8161 cagcaatttg gacttgctgg caacagagat agaaaccata ctgaaacttc aataagaaca
     8221 atcatggcta ccaaaagaag aacggattac caggtggatg aggaggcatt gaaacgtatg
     8281 atggccgggg atgtaacagc attggacaaa atggtttctc ccgctgaggc tccggaaaca
     8341 ataagccggc ctgccccttc ccaggagaag caggagaaga actccgccgg ttctcccaaa
     8401 cagcagataa gaaaatccac ggatgaggcg tccggcccgg atgaataccg gcaacggttt
     8461 ctgaaagaga gactgtccgg ttcaagaagg cagacctata ttcacgatgc tttgtacagg
     8521 actgttgcca aattattgcc tgtcattgcg ccggatatgt cagttcccat gtttttaggc
     8581 agtgtcctgt ccgaccacct ggaaagatat caggatgtta tcaatgaaat atataaccag
     8641 gaagcaaatc aaaacccttt ggaatggaag aaatagttta tttgtcagta aggatcggct
     8701 gtgccggcta cttgttatac aagttatgga atcagaaaaa acggatccgt aagatttgcg
     8761 ggctgctcta tacccccggg aaaaaggaga aggaggaaga gggaacatcg tgcggtacag
     8821 gaccgggtga tgtgatgggg gctacccgat ttgtctatct ggacgaaaac gcgggtacgt
     8881 ttgccgcccc ctacatgagc cagccgttgg aaaccgggaa cgattatctc ggagaggaag
     8941 aggcggtgcc ggagaatgag gtggagtgcg ggctccctct ggaagagatg agactgttga
     9001 aagaggaaca ggaaaggctg gacgaacagg ctcccggcac ggaaggtatc actccggtaa
     9061 tcacgtccga tgacctgctc aatgccggcg atgtgctgct taatctggat ggcgcccaaa
     9121 tgaacgagga gaaaaaacgc cgggctgccg tcaccttgca tgccatccgg gaaacggata
     9181 tgtttgaact gatttcatcc caggtggaga ataaaagcct gattgaggag ctgatggacc
     9241 aatatatcgg caatgatgga aatgtattgc cggtgaaaag aaagaaaaat gaaggacagc
     9301 cggaacatgc ctggagacag tttctctgaa cccggcggca gtcagtccga aacgaaagga
     9361 agaggctttg gaagcacctg ccttgtaccg ctatcatggt tgcctgttcc cggttccttt
     9421 gtcatgcctg gttctttaaa tgtccatata ttttgattgt tcggttggtg acggattcct
     9481 ttccggaatc atatagaagc taagatgtta atgaaaaata attcattacg tttatcctat
     9541 ttttttttaa gaaaaatatt gtgttcttga atggaatctg tatatttgag acagattgca
     9601 aaaatgaatt atagagccgt gatttatcag gaaaaacgaa tgtcagtatc gcggctatgg
     9661 gatttgaata accggtaagc tatatcagca ttgcaatatt ttaaaggagt gaaatgttgc
     9721 aagtatgaac taactccaat tttaaaggct atgggaaaac agattgccaa actaggtatc
     9781 cgtccggaag acctgaaaga caagacggtc acttcggaac agttggaaaa gacgaaaggc
     9841 gggaaagccg ccgggtctga agagtgtgta tgctactgcg gttgctatac cgatgactcc
     9901 gctttcggtg tagatttcaa ctggtggtca agagactggg attgattcct gcattgtacg
     9961 atgctttgta aacagattag ccactatgga aaaacaaaaa atgaataagt ttcccctggt
    10021 caaattgttc acagttgacg gggcgtcctg ttatttatat gacggcagag cgaacatgtt
    10081 cctgtcgctg tccgagactg agaagaacct tgtctgtgaa tacatggcgt cgtatggaac
    10141 tactgaagga gagccttgcc cggcctcctt cccttccggt gccgccgctt tcatcgcccg
    10201 tcttaacgga aacggcatcc tgcttccggg tcccctggaa gcgaggacac cttccggaat
    10261 gcgtggtgag gaacagttat ggcaacaatg ggaggaggaa gccattccca aaaaactgac
    10321 actagagatg accaatacct gcaatctgcg ttgcaggtat tgcccctata caatcaacga
    10381 gcaacgcgga caaggaaaaa tgcacgcctc ccatcacttg aaagaggagg atgcgcggaa
    10441 agccatttcg gattatttcc atgaatacac acgtattttc cgcaaggtgg aaccggaaca
    10501 caggacactg ttcctgaaac ggaatcctcc cgccgtcagt ttctacggcg gagaggcgct
    10561 tctgcgtttt tccctgctgg aaccgttggt gaaatatgtg ctctcgcttc cttgggagga
    10621 acaccatata cctgcggaga aggtcgtata ccacataacg accaatgcca cgctgctgac
    10681 acgggagatg gtggaattct ttatacggta tcatttcact ctcgccatca gcttcgacgg
    10741 tccgccggag gagaatgaca agtaccgcgt gttcaaaaac gggcagggta caggaacggt
    10801 ggtggagcgt gcccttgaca tgatccgtga ggtttcggaa gagtacctgc tgaaccatgt
    10861 acacatacag gccgtgctgg ctcccgaata cgaccatgac aaagtcggca gatactttga
    10921 ggggcgtagc ctgaacggtt gttatggcgg ggtccgtcag ttttcctacc tggaattcag
    10981 tgattacagt gaaagcaaga agacggacaa gcaactggcg cagttcaata tccgggagcg
    11041 gatcaaggaa ctttatgaaa agggcctctc tccggaggaa cggtaccagt atattcttcg
    11101 tgaccccctg atcagcgcat ggctgcggta tgtgtacgcc attctgacca aggtcggtga
    11161 cgcaccctca cacaaagcca gatatttcaa ttcatgctat atcgggcgta ccaatctgtt
    11221 gcttgacaca tacggcaacc tgcatctctg cgaacggtcg gatttctcca tgcctgtcgg
    11281 tgaggtgaac tcgggcatca accgtaccgc cgtccggcaa atgtaccgtg atttttttga
    11341 gaagacagac agcccgtcct gccgttcctg ctgggccggc cgcttctgta ccctctgcac
    11401 cgccgcgctt atcaagaacg gtgcggttca ggaacctgac cgttccattt gcaggagctt
    11461 gcggcacgca caggagaaac agatagagga cttgctgtat atcaaggagt attatccgga
    11521 aattctggaa cagatggaac gtatgtattt ccaggcgaat gacataacgc tcggcgcttt
    11581 ccatgcctac gtcaaggaac aacaagacgt cgccccatga ggttcagggt gtcctaccag
    11641 catgactcca tgcagtgcgg tgcggcgtgt ctccgtatgg tctgcaagca ttacggaaag
    11701 gaatatgccc ttgactttct ttccgagcaa tgcggctgca tgattgacgg ggtttccttg
    11761 caggccattc gcgagacggc ggaggacctg ggattccgga cattcgccgt atcggtcggt
    11821 ctgtccgaat tgcaggccgg atggtgtccc tgtatccttc attgggagcg taatcacttt
    11881 gtcgtcctgt acaggattca taaggataag tatcatgttg ccgatccggc caaagggacg
    11941 gtcatatacc ggaaagaaga tttcctgaag cgttgggcgg gagacgggga acagggaatc
    12001 gccttgttac ttgaacccac acaggctttt tatgacttct cttcgggcat ggaaccaaaa
    12061 gtcccgtccc ctttccgttt tttatggagg tacatagctt cttataaaaa agcatttgca
    12121 tcggtcgcct tgaccctgct tgtcggcagt ctcgtacagc tggtgcttcc gctgcttgcg
    12181 caaatgatgg tcgacaaagg tatcggtcat aaaaatatcc cgcttgtcta tctgattctc
    12241 ggcggccagc tggtgcttgt gcttggttct gccgccatgg agtttgtccg caaccgtctt
    12301 ctgctgtttg tggggatgca tgtcaatata tcattgataa ccgacttctt cgccaaactg
    12361 ttccgcctgc cgatttcatt cttcgagaca aggaccaccg gggatctttt gcagcgtatc
    12421 gtcgatcacc gcagggtgca ggattttctt accggacagg ttctctccgt cttgttctcg
    12481 gtaatggtct tgtgcatatt catgggcgtc ctgttttcat ataacagctt cctgttcctt
    12541 gtctttctgg cgggaagtat cggctacggc ctgtggacca tgtgtttcct gcataaacgc
    12601 aagttgtttg actatatgat tttcgagaaa cagtcggcca gcaacaacaa ggtataccaa
    12661 ctccttactt tcatgcagga gataaagctg caaggcggcg agggaaggcg cgccggggaa
    12721 tgggaggcgt tgcaaaagga gcttcttgac atccagatga ggtctttgag cctgcaacag
    12781 ttccagcaga caggcgggat atttatcagc cagtccaaga acctggttgt gacggtcatt
    12841 gccgccgttg ctgtcattga aggggagatg actttgggta tgctgcttgc cgtgcaattc
    12901 attatcgggc agttgaacat cccgattgaa caactgatgc agtttctcta taatttccag
    12961 aatgtgcggc taagcatcga gcgtatcagc gcgattcatg ggaaggcgga ggaaagaacg
    13021 gggaaagaga taccggaaca gccggagatt tcccgaaagg atatccggat tgaacacctg
    13081 gattttaaat ataacctgca tggcaaagcc aaggtgctgg atgacataac gctgaccatt
    13141 ccggcacaac gtaccaccgc catcgtgggc gcaagcggaa gcggaaagac cacccttgtc
    13201 aaactgttgc tgggctattt tgctcctaca agcggaaata tcttcctggg agacactccc
    13261 ttgcaggatt atgatatgac atcgtggagg cacagctgcg gcgtagtgct gcaagacagc
    13321 catgtgtttt ccgaatctct ggcaaggaat atagcagtgg aggacaagca tatagaccgt
    13381 acacgtctcc ggaccgccgc ccgtcaggcc aacctggaag agttcataga gaaactgccc
    13441 ttgaaatacc agacgatggt gggggctgaa ggcgtggggc tgagccgggg acaggaacag
    13501 cgtatcttta tcgcccgtgc gctctataag gacccttcgt tcgtgtttct tgatgaggct
    13561 accaactcgc tggatgccaa caatgaaaga atcattaccg ggaatctgct ggatttctgc
    13621 aaaggaagga cggtcctgat agtggcccac cggttaagca ccatccgtca tgccgacaag
    13681 atagtcgttc tgcataaagg caggattgtc gaagagggta cccatgacga attgtgcgcc
    13741 cgtcatgggc attattatga gttgattaat aaccagttga ttgctatggg gtgaagatag
    13801 tattttttaa cttttatatg tcaaaaaagc cttttcgtca aggtcttgct tttttctttg
    13861 ttttccgtat tttgacaata gagtataaac ta
//
