LOCUS       c00002_gnlPro..        16725 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IGCGABHK_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:00:48
            Original ID  :: gnl|Prokka|IGCGABHK_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16725
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16725
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3167:6725](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3168..6725
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16725
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16725
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(595..1749)
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1956..3134
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLWKDHKVHKGD
                     KNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGFLY"
     CDS             3168..6725
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-18, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.2e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.9e-31, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.6e-11, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.7e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00025, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-24, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6850..7038
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7049..7909)
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVIPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7937..8767)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-28, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8764..9990)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10463..11749
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11712..12044)
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12072..14837)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.2; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.6e-20, bitscore:
                     64.2, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMRWMKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSW
                     RHKMNDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTP
                     IVEEAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGL
                     SGSTPAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHN
                     DRIAPGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQL
                     AMDILEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVAT
                     QQVVLYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQ
                     LSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVN
                     ILLRLVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDT
                     DYHTLADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMIS
                     AEHIRNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQS
                     CEAVAAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLH
                     TDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLT
                     ACSLDEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVC
                     DMDKDFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIAR
                     LKKAASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15158..16384)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSLFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 tttagatatt aaagtatatt gagtaaacta attcagttat aacaaacgaa gttgtcaact
       61 aaaaccagta cacatcacca attccaattt agcagtatct tcaaagagtt tccattgctt
      121 gaaaccagag tttcatcggt gtgaaactgt agtttcatcg gtgagaaact agagtttcat
      181 acgcttgaaa ctttagttcc aaacgctcga aactatctga aactactgtt gatttgattg
      241 acttaaccgc atgttccaat cacattgaac gcatcagcta cttcaatagt actgctctct
      301 ctgaaaacat taaatcatat atcagtcaat aatacataaa ttatcagtcc ttaatacttg
      361 atttctcaat tattaatatc tgagaaatca aacgttaaca gttgagatat cagatattaa
      421 catcctgtaa atcaaagaat aacacagtaa aaacggtatt tatcaggacg atgcagagtg
      481 agagcaagtc cttgctctca ctctgctacc actggatctc taacagctaa aacatcgatg
      541 aataaaggga tacagacgaa ctgttagagc atgagagcaa aagcactatc tttttcactg
      601 ggggagagta agcaaaagaa acgcacgata ccggctttga ggcgtcaccg gtactaacgg
      661 caaatatccg gcacacaccc gattattctc tacggacaaa gggaacgaag ccgacatctg
      721 ccgatgttcc tccaaagcct gaccggctaa aggataataa tcaatccgaa aaactccttc
      781 cgcatccgca gccaaataac gatccgtcaa gagccatgcc accaccccca tattcattcg
      841 cagattaatt tcgacacaag gatgaatccg gtaaacaggc gcttcatccg gaaaatgaca
      901 aatcatcata tccactccca agtatccatg ataaaagcca ccgaacaaag ctgacaattc
      961 ttcttccaaa cgagtccgca gcctgataaa ttcttcttgt ggcacataag ccgatagttt
     1021 ctgcagaatc ttctcgtcag acagcaagtc attccctgca tacatcccac tcccacccgt
     1081 gtggaagacc gaatatccgg caaaaacaac ccttcctctc ccgtcagcat aaaactccat
     1141 agcgaaatct tccaccttat tatatatagg ttcgcctacc accccaccct gagaagcagc
     1201 gacacgggca caccaaccgg aaataaaagt agtaaatatg cctttacacc aattcaatcc
     1261 tttcccgctt ccggaaagcg gagcttttaa caagcacgct tcccgccctt cgacgaacgc
     1321 actgcactcc gccaaagtac tcaaataaaa agattctcca cagaagtatt cattcaaccg
     1381 caacccaggc aacaacttta ccgcctgcag acgatgcgaa tgctctctca gaatattcat
     1441 ataatccgca gaaggcagct ccgtctgacc tgcccccaat gtcatcaaac gcttccgcaa
     1501 agcagggtcc caaccccacg gagagaactt ccggtcttta ccgtcagcca cttccggttc
     1561 cgtcaacaag gccacatcca tgcccaaaag ttcactcttt gttttcagga agtccgcatt
     1621 ataagcagac ggtgcaagca ccgcacttcc cgcttcggca taccacatag gaagcaacgc
     1681 caggtcactc gccatctgtc gggcggaagc cggcgccata tagttcgtct caccgcttgc
     1741 caacgccata tcatgctccg gattgaatat ataaacaggt cttttcgtca tgtcaaagat
     1801 ggattcaaca cattattctg caaatatata caggaaataa tcaggaactt acacaataaa
     1861 gagaaactta taaattaaag cacatttttg ctatctctac tttgcaaatc ctaaaaaaag
     1921 cactatattt gccagccgaa aaacaaagaa acgaaatgga atcattctat cgcacacacg
     1981 cctacctcgt tgagcacacc aatgcccccg ttcgccgcga tcttatggac gagatcgact
     2041 ggagtgaccg tctgattggt atcaaaggga cacgtggcgt aggaaaaacc actttcctcc
     2101 tgcagtacgc caaagagaaa ttcggcaccg accgttcctg tctgttcatc aatatgaaca
     2161 acttttattt ctccggtcac agccttgttg acttcgccaa cgagtttcag aaacgtggcg
     2221 gaaaagtact gctgatcgac caggtgttca aacatcccga atggagcaaa gagctacgaa
     2281 tgtgctatga ccgtttcccc agcctgaaga ttgtcttcac cggttcttcc gtcatgcgac
     2341 tcaaagagga aaacctcgaa ttgcgtgaca ttgcgaaaag ttataacctg cgcggattct
     2401 ctttccgtga atttctgaac ctgcagacag gaatgaaatt ccgggcatac agcctcgaag
     2461 aaatcctcag tacacatgaa cagatagcca aaggagtact ttccaaagta cgaccgctgg
     2521 attattttca ggattacctg catcatggtt tctacccttt cttccttgaa aaacgtaatt
     2581 tctcggagaa tctgctgaaa acaatgaaca tgatggtaga agtggatatc ttgctgatca
     2641 aacaaattga gctgaaatat ctttcaaaga taaaaaaatt actatatttg ttggctgtgg
     2701 acggaccgaa agctccgaac gtgagccaac tggcaagtga cgtacagaca tcccgcgcta
     2761 cggtaatgaa ctatatcaag tatctggcag acgcgcgtct gattaatctg gtttacccga
     2821 aaggagaaga attcccaaag aaaccgtcaa agattatgat gcacaactct aacctgatgt
     2881 actccattta tccggtgaaa gtggaagaac aggatgtact cgacacgttc ttcgttaaca
     2941 ctttatggaa agaccataag gtacataaag gagataaaaa cgtctctttc atggtagacg
     3001 aagtgatgcc gttcaaaatt tgtgcggaag gtacaaaaat aaagaataac ccggacgtga
     3061 cgtatgcgtt gcaaaaggct gagataggcc gcggcaacca aatacctctt tggatgttcg
     3121 gattcttata ctaaaaagat ttatttactt aaatatttaa tttagttatg actaaacaga
     3181 agaaattcat cacatgtgat ggtaaccaag ctgcagcaca tatctcgtat atgttctctg
     3241 aagtagcagc tatctacccc atcactcctt cttcgactat ggctgagtac gtagacgaat
     3301 gggctgccgc aggacgtaag aacatcttcg gcgaaacagt attggtacag gaaatgcaat
     3361 ctgaaggtgg tgctgccggt gcagttcacg gttctcttca ggctggtgca ttgactacta
     3421 cttacactgc ttctcagggt cttcttttga tgatccctaa catgtacaag attgccggtg
     3481 aattcttgcc ttgtgtattc cacgtttctg ctcgtacact ggcttctcac gcattgtgta
     3541 tcttcggtga ccatcaggac gtaatgtcag ctcgtcaaac cggcttcgct atgttggcag
     3601 aaggttctgt acaggaagtt atggatttgg caggtgttgc tcatctggct actatcaaat
     3661 cacgcgttcc gttcatgaac ttcttcgatg gtttccgtac ttctcacgaa atccagaaga
     3721 tcgaaatgtt ggaaaacgac gacctcgctc cgctgatcga ccaggaagct ttggctgaat
     3781 tccgtgcccg tgcactgaat ccgatgaagc cggttgcccg tggtatggct gaaaaccccg
     3841 accacttctt ccaacatcgt gaatcatgca ataactacta tgaagcagtt cctgctatcg
     3901 tagaagaata catgaacgaa atttccaaga tcacaggccg caaatacggt ttgttcgatt
     3961 actacggtgc agaagatgca gaacgcgtaa ttatcgcaat gggttctgta actgaagctg
     4021 cccgcgaagc tatcgaccac ttggtagcaa acggcgaaaa agtaggtatg gttgccgtac
     4081 acttgtatcg tccgttctct gctaaacact tcctggctgc tgtacccaag actgcaaaga
     4141 gcatcgcagt gcttgaccgt acaaaagaac cgggtgctaa cggcgaacct ctttaccttg
     4201 acgttaaaga ctgcttctat ggcgcagaaa atgctcctgt tatcgttggc ggtcgctacg
     4261 gtctgggttc aaaagataca actccggcac agatcatctc tgtattcgaa aacttggcta
     4321 tgccaatgcc gaagaaccac ttcactatcg gtatcgtaga cgacgttacg ttcacttctc
     4381 ttcctcagaa agaagaaatc gctctgggcg gtgaaggtat gttcgaagct aaattctacg
     4441 gtctgggtgc tgacggtact gtaggtgcca acaagaactc tgttaagatt atcggtgaca
     4501 acaccgacaa acactgtcag gcttacttct cttacgactc caagaagtcg ggtggtttca
     4561 cttgttctca cttgcgtttc ggtgatactc cgatccgttc tacttacttg gtaaatactc
     4621 cgaacttcgt tgcttgtcac gttcaggctt acctgcacat gtacgacgta acacgtggtt
     4681 tgcgtaagaa cggttctttc ttgctgaata ccatctggga aggcgaagaa ctggctaaga
     4741 acctgcctaa caaggtgaag aaatactttg cacagaacaa catctctgta tactatatca
     4801 acgcaactca gattgcaatg gaaattggtt tgggcaaccg taccaataca atccttcagt
     4861 ctgcattctt ccgtatcaca ggcgtaatcc ctgtagatca agctgttgaa cagatgaaga
     4921 aattcatcgt taagtcttac ggcaagaagg gtgaagacgt tgttaacaag aactacgctg
     4981 ctgtagaccg cggtggtgaa tacaagactc tgactgtcga tcctgcttgg gctaacctgc
     5041 cggatgatgc aaaagcagaa aacaatgatc ctgctttcat caacgaagta gttcgtccga
     5101 tcaatgcaca ggacggtgac ttgctgccgg tatctgcatt caagggtatc gaagacggta
     5161 cttggtatca aggtacttcc aaatacgaaa aacgtggtgt agctgcattc gttcccgaat
     5221 ggaatgctga aaactgtatt cagtgtaaca agtgtgctta cgtttgtcct cacgcttcta
     5281 tccgtccgtt cgtactcgat gctgaagagc agaagggtgc taagttcgag caactgaaag
     5341 ctgtaggtaa agcattcgat ggtatgacat tccgtattca ggtagacgtt ctcgactgtc
     5401 tgggttgcgg taactgtgcc gacatctgtc cgggtaatcc gaagaagggt ggcaaggcat
     5461 tgaccatgaa acaccttgaa agccagttgg ccgaagctga taactggact tactgcgctg
     5521 aaaacgtgaa gagcaaacaa cacctggtag acatcaaggc taacgtgaag aactctcagt
     5581 tcgcaactcc gttgtttgag ttctcaggcg cttgctccgg ttgtggtgaa actccgtacg
     5641 tgaaactgat ttctcagttg ttcggtgacc gtgaaatggt tgctaacgct acaggatgtt
     5701 cttctatcta ctccggttca gttccttcta ctccgtacac tatgaacgaa aagggtcacg
     5761 gtcctgcatg ggctaactcc ttgttcgaag acttctgtga atttggtctg ggtatggaac
     5821 tggctaacga aaagatgcgt gcccgtctgg tgaaagtaat gaacgaagct atcgcttctg
     5881 attgctgccc ggctgaatac aaagaagtat ttgctgaatg gatcaacaat atgctggatg
     5941 cagaaaagac taaggaactg gccgaaaaga tcattccgat ggtagaagct gctaaagata
     6001 aatgcaacca ctgcaagcaa atcgctgatc tgcaacaata tcttgttaaa cgcagccaat
     6061 ggatcatcgg tggtgacggt gcttcttatg atatcggtta cggtggtctt gaccatgtaa
     6121 tcgcttccgg taaggacgtt aacatccttg tattggatac tgaggtttac tctaacacag
     6181 gtggtcagtc ttctaaagct actccggtag gcgctatcgc taagtttgct gctgcaggta
     6241 agcgtgtacg taagaaagac ctcggtctga tggctactac ttacggttat gtatatgttg
     6301 ctcagattgc tatgggtgct gaccaggctc agactctgaa agctatccgt gaagctgaag
     6361 catatccggg accatcactg atcatcgctt acgctccatg tatcaaccac ggtctgaaag
     6421 ccggtatggg taagagccag gaagaagaag aaaaggctgt taagtgcggt tactggcact
     6481 tgtggcgtta caaccctgct ttggaagaag aaggcaagaa tccgttccaa ctggatagca
     6541 aagaacctaa ctgggaagac ttccaaggtt tcttgaaggg tgaagttcgt tacgcttctg
     6601 taatgaaaca atatcctgct gaagctgaag aactgtttaa agctgctgaa gaaaacgcta
     6661 aatggcgtta caacagctac aaacgtcttg ccagagaaaa ctggggagct gatacagctg
     6721 aataataagt agaaatactt tatacataat aaaaggcagg aatcctggaa acagattcct
     6781 gccttttttg tttatatctt agaagtaacg attacttctc acgaagatat tcattaaaac
     6841 tctaaagata tgatcggatt tgttatttgg attatcggtt tgatactgac tttcagagct
     6901 gccatagaga tttggaatat aaatgcggct gtagagaaaa gacttatagc gattgtatta
     6961 atcgttctta ccagctggct gggactactt ttctactact tctatggtaa agaaagaatg
     7021 gcaggatggt tgaagtagtg tttgcatatc aatctttctc aggaatccaa ctgtttacca
     7081 gttcctgatg ttcttccatc cattgacggg cagcctgtct ttccgttgtc tgcgcctctt
     7141 ccagagcagt cattaaagag ctgatttccg catctgtcag acgaatgttg cccaaaagtt
     7201 cggcagcaaa agggtctttc tcgctaaaac ctttccatgc tatggtatga atggattccg
     7261 tatttccata tatcagcttc gggtcctgaa gaactttcag cttgaaacgg tcgaacatcc
     7321 agtgaggcgt ccatcccgtc acgacaatcc agtctttctt atcaatcgct ttctttaggg
     7381 aagcagtcat ggcaggtccg ctcgaagtca tcagtttata atccaatcca tagtctttga
     7441 tggcctgatc ggtagctttc ataataccgg ctccggcatc aataccgaca atctgaccgg
     7501 agaaacgttc cttttccgcg ttcagttctt cgattgagtt gatcgtaacg taatccggaa
     7561 tcaccagccc gatacgggca ccatcataaa tatccccgat aacttcgagt ttatccccgt
     7621 attgtttcat ataatcttcc atagtgacag gcatccagac atccataaat acgtctgctt
     7681 tcttacggga gatagaggta aatataggtg caaggtcggc attcagcaac tttacatcgt
     7741 acccctgatc ttcaaaaatc gctttggcaa ggtttgtcat tgcaatacct tccgaccagt
     7801 tggcataagc gatacttatc ttcttactct ttccgttgtc tccgcaggaa acgaaggtta
     7861 agagtatgcc ggcaataaac attgccgcaa tcatttttat cttattcatt gattattcct
     7921 ttctttggtg tgattcttat ttctttttac tttttctgtt atctgccata ccctgagtga
     7981 tgcggtccag cacgatcgcc aatatcacga ctgcgatacc gccttcaaat ccgagtccga
     8041 ttttcatttg ggtgatacct ttcagcacga tttctcccaa ccctcccgca gaaatcatgg
     8101 cggcaatcac taccatcgaa agtgacatca tgatcgtctg attgattccc gtcagaatag
     8161 taggcaatgc caaaggcaat tgcaccttat aaagaagctg ccagggagta gctccaaaag
     8221 aacgggaggc ttctactaca tttttaggaa cctgacgaat gcccagacca gtcagacgaa
     8281 ccacaggagg cattgcaaag atgatggtgg caaaagctcc cggcacagtt cccaatccga
     8341 agaatagaac ggcaggaatc agatagacaa aggcaggcat tgtctgcata aagtcgagga
     8401 cagggcgcat tatcttgtta caacgatcac tgttggcagt ccagattccc aacggaacgc
     8461 ctaaaagcaa tgccagacaa gtggaagaaa gtaccaatgc caatgtctgc atcgtttctt
     8521 cccaaaagcc catgccgtaa ataagcaata aacccaagag ggtaaatacg gctgtcccct
     8581 tacccgactt aaaccaggcg agcgcagcca gcactgcaat tgtgatataa aaaggtattc
     8641 caaacagtac gtgctgaaaa ccgtctatga atcctccgat ccccatgctg agagcatcaa
     8701 aaaaggaagc aaaatgttct gtgagccaat taatggcagt ctctatatat tgtccgatat
     8761 ttatcataat tctattgcgt tttgaatgat ttcattaatt tcttctttat cttttcccgt
     8821 tacttcgatg atcaatgagg aaagtggcac tacgccttca aactcccgat tctcatttac
     8881 gacccagatt ggcgagttcg tttttgtcat caacggaaga atatcttcca gcaccgtatc
     8941 acccagcact gaatgaactt catgccttac tacggactcg atggagcgga tttgctcttt
     9001 tcgtagtttc agcaagtcat tcaaccgcac ctctcctact aacagattat tggaatcgac
     9061 taccggaaga acggtcagat tccgttcgcg catcttacgg atcagcacct ccgggccttc
     9121 tttcttcaaa cgtgccacta tgggtttatc taccataaca gaggaagctg ttataatctt
     9181 gcttcgatct acattctcca caaatcgttc tacataagcg ttggcaggtt cggtcaggat
     9241 ttcttccgat gtaccgattt gtacaatttc tccatccttc atgatagcaa tccggtcacc
     9301 caatttaatc gcttcactca ggtcgtgagt aataaagaca atcgtttttt tcatcttcga
     9361 ctgcaaagtc agcagttcat cctgcatctg cacacggatc aaaggatcga gtgccgagaa
     9421 ggcctcatcc atcaacagga cttcgggatt attggccaaa gcccgcgcca gcccgacacg
     9481 ctgctgcatc ccacccgaca gttcacttac catctgattc tcgtagcctt tcagccccac
     9541 cagttgcatg ctttccatcg ctttctgctc ccgttctccc ttttttactc cctgtagttc
     9601 gagcccgaaa gctatattat gcaagacaga acggtgagga agcagaccga agttctgaaa
     9661 gaccatagcc agttctttcc ggcgaatctg caacagttcc ttatccgaca ctttggctat
     9721 gtctgttcca ttgataatca cttctccgga agtagggcgt atcaaacggt tgatgcagcg
     9781 gagtaaagtg gactttccac taccggacag ccccataatg acgaatattt cgccttcatt
     9841 aatggaaaga ttcgcatctt tcaccgcaac tgtacatccg gtcgctttca atatttcact
     9901 ttttgtttta ccttctttca acatcttcaa agccttctgc ttctcattgc caaaaaccag
     9961 atagagatct ttaatttcta ttttactcat acaataaaat ggtttaggtt attaaaataa
    10021 tatacacagc aagacaagaa caaacgataa caggaatctt tctttatatc gtataaagtt
    10081 ctgatttaaa tacgggacaa ataacaatga atcccgaaat aattaataaa atgattattg
    10141 acagactgag taattaaaaa aggaatagaa tttgataaga taatcctttc aacgaatagc
    10201 aaaaaatagc atttttatgt ataaaaacag cctgttccag tatcttgctg gcacaaagat
    10261 acaaaaaacg gattaaacat acaaattata ttcaaaatcc ggggcataca gagggcttta
    10321 tttgtaatga tatggaaagt ttccgggtaa tattccccta tcactcagca aaatagaaca
    10381 aaccggcaga taaatataaa ataagtttga atatttcact taaacaccgt atatttggcg
    10441 tcaataacta aactagattt atatgttcaa cagggctatt acaattttcc tggggaagga
    10501 taattgtcat tacacaacaa aagaaaaaca aacaggtact gccacactag acgacaaaag
    10561 ccaagtacag ttccttagta aaaagaaccc caaaatgccg tttttctata gccggcggaa
    10621 tctctacatg ataggtttcc tgctcgcttt tatagtgact ctgctcgaat ttatacgagg
    10681 acggcatcaa aactttatgg tcttctcgga cgctactcaa ttcttctggc aaggcatcag
    10741 cccatacaca actgaatttg tagaagctca cggacgctac ttcctttatt ctccagtttt
    10801 cacggtattg ttcgctccgt ttgcgtatct gcctgcatgg ctgggacctt tcgcgtggaa
    10861 tctattcaat tattcgctgt tctttatggc gatcttcacg ctgccccaac aattcaccca
    10921 gcagcagaaa tgccgtatgt tcctttttct gttactgatt ttaggacaaa gtttactttc
    10981 atttcagtat aacataacgg tagcctattt attcttattc gcctatacgt tattggaaaa
    11041 agaccgtgga tttctggctg ttctgttaat catgatttcg ggatgtacca aagtatatgg
    11101 aattttcgaa ctggcattgt tgctgtgcta tcctcacgta tggcgtaact ttggctatgc
    11161 cgttacaatg ggcattgtat tgcttgcatt accgttaatc aaaatagctc ctgcagattt
    11221 gctcccctat tatgaagaat ggtgccatag tcttgctgtt catcagtccg ccggagctta
    11281 tgattcattt ttctatgccc gccccattgc agcatggaca ttgccacact tccgtgcact
    11341 tcagatagga atgctcggct tgctgactct gctctttttg gggaatttcc gcaaatggtc
    11401 gtcttttgcc ttccgtgccc aggctttggg cattctcatg ggctgggtag tattactgag
    11461 tgactccgcc gagaagcata cctatattat cgcattggca ggtttcatgc tctggtattg
    11521 gagcagacca acacgtaccg caacagacaa gattctattt tggtgctgtt ttgtgctgtt
    11581 atgtatcgtt cctatcgaca tattcgtccc tgtacccatc agagatttca ttaccaggac
    11641 cttatggctt catgtatggg ttttctttat tgtatggata cggatgatat ggcttacctt
    11701 ccttgcatcc ttcattcatc cacgtgccac aaatgttctt tcagattaac gcatccgtta
    11761 gctttgaaag aaacttcttc tgccagcaag agttgttttt gttccaccca accgggcacc
    11821 agccttccgg tggaatttac aactctatgg cagggaatgg ataattcatc cggcacttct
    11881 ttcaatgcac gtcccaccat ccgcgagcat tggggtgccc ccaacagcaa agcaatacct
    11941 ccataagtag atacttttcc cacaggtatc tgggatacga cttcgtacac ttccttccga
    12001 aaggattcgg aaaagctctc tttatctact ttataatctt tcatatatcc ctctttacga
    12061 tatcaatgaa atcatccttt ccttttcagg aaatctgtcg ggctctctcc aaactgctct
    12121 ttatagcact tggcgaaata agaaggtgaa ctgaaaccga cttcataacc aatctccgct
    12181 acggtcatgt ccgaagaagc aagcaaagaa gctgccttct tcaaacgggc gatacggagc
    12241 aattcattcg gagagtagtt agtcaatgat ttaatcttgc gataaagctg cacacggctt
    12301 agtcccatgt ctttgcccaa gtcctccaca ttcaaaccgg agtctcccat tttctcttca
    12361 atcaatgact tgaatctttc tacaaaatcc ttgtccatat cgcagacatc ttcttttgcc
    12421 aatgtctgcc cgtcaccaaa gaactgtttc agacgacggt gagaatcgat cagattgcgg
    12481 acacgtgcca gcaacagctg tgaactgaac ggctttgaaa tataagaatc cgcaccaccg
    12541 tcatatccct gaatacgctg ttcgtccagt gaacacgctg tcagcagaat aaccggaata
    12601 tgacaggtct gtaactcact tttcagccgg cggcaacatt caatgccatc aatgcccggc
    12661 atcatcacat cagaaatgat caggtccgga acatacttca tagccttacg gattccttcg
    12721 gagccgtctg ccgcttcaat caccgtatag tctgtatgca acaacgtatg gacatacgaa
    12781 cggatatcct cattatcatc aataatcagt acggacggtt tggaagagtc atatcctttt
    12841 tccagttctt cctcttccgc caatagaaca tctgttgtac gggaatccgc agaaacaagg
    12901 gtggtatccg gttcggcagc aacagcctca caagactgta caggcagttc aacggtaaag
    12961 accgtgccct gtttctcatc gctctctacg gagatcatac caccgtgcat ttctacgaag
    13021 gcttttacca atgccagtcc gattcccgaa ccggtatggt gcatatcgat cttatagaaa
    13081 cggtcgaata cattgcgaat atgttcggca gaaatcatag aaccggtatt tgccaccgtg
    13141 aaacgtatcc atcgcttgtc ctctttacta agggaagaca gacggacggc tattttcccg
    13201 ttttccggtg taaacttaaa ggcattggac agaagattga aataaatacg ttccagcttc
    13261 tccatgtctg ccagtgtatg ataatccgta tccggcatac tatcaaaaga aaaatggata
    13321 tgcttcttac gggctgccgc ctgaaaagac tcattccatc cttcgaaaga agaaaggaca
    13381 tccaccgtaa ccggagtata ttccatcttg ccgttttcat atttacggaa atccagaatc
    13441 tgattgacca gacgcagaag aatgttcaca ttccgctgaa tcagcatgag catccggtgc
    13501 tgatctccgc tcagtgtctt gtccgccaac aaatgttcta ccgggtcggc aaccaatgtc
    13561 aacggagtac ggaagtcgtg agaaatattg gtgaaaaaga ccagcttggc atgggtagct
    13621 tcttccagtt gatgagagag ctgtatcaat tggtcacgct gttcttccag tttgtcacgc
    13681 tgctcttcca attgctgttt ctgcttaaaa agctctttat tcaagcgatt cttagagcgg
    13741 agtgatttat aaacgaccaa taataaaccg gctaccaata aaaggataat cagactgccg
    13801 tataaaacga cctgttgtgt agctacctga gagaggtatc caccgatacg tccgttgagc
    13861 gtttcaatct ttttgtcgag ttcggaaatg tgtgtggtct gcaactgcat gacgtgtgcg
    13921 ttggtacggt ccacaacagc ggtattcatc accgtttctt tgggataggg tttcttctcc
    13981 agaatgtcca tagccagttg cagtacctta tcgccattgg tcggatagat aaaggtggca
    14041 tccagcacac tgtccagtac cagttccagt ccgtttccct tacccggcaa ggcatctatg
    14101 ccgacaaaaa tcatttcctt ctcccgccct gccatctttg ctgcctgata ggcacccgga
    14161 gcgatacggt cattatgggc atacacagca tcaatcttag gatgcctccg aagcatacta
    14221 tccatttcta tctctgccgg accacgttcc cacgcagcat ccgctttatc aatcagcttt
    14281 atatccggga atttactgat ggcagccata aatccctgat gccgttccat tgcaggagtc
    14341 gaaccgctca atcctgtcag ttctactata tttcccttcc ctttcagact ggaggcaata
    14401 tagtttccta ccgaacgacc gatttcataa ttatcggctc cgatataggc agtatattta
    14461 tccgaaagaa tcttccggtc tacaagaata acggggatgc ctttctgata agcttcttct
    14521 acaatcggag tcataggagc agcttcgtta gcggaaataa tcagcagatc gactccttcg
    14581 tccataaaat aatggacatc ttccgcctgc ttactgttat catcccctgc cgaacggatt
    14641 tccaccgaaa caccattata aaacatcgct tcccgaagaa tctcatcatt catcttatgt
    14701 cgccatgaat catcgctgca ttgagccacc ccaatacgaa aacggggtgt atcctgccgg
    14761 caagccgtca tcccgattaa accaaacagc accagcatcc acttcagata tctcatcgtc
    14821 ttcatccatc tcatcatttc atagttcttt ctgtaatcca attaagaaca aaaataagaa
    14881 ataatactgt aaagttctct aacttcagct atttattatt ctaaaaagaa ggaaagcagt
    14941 cctctttcag accatcggaa agtattaaca aaagtataaa gcgtaaaaca aacacttaat
    15001 caatgttata aaacatagcg ttttacttgg ataatttgca gatttcacag aagtccgtat
    15061 ctttgcactg tgtttttcat agtattagat ttaaggttaa caaaggttgg agcaaggcgt
    15121 tgctcctttt tttatgctct gacctttcat ctaccggtta gttttcatcc cattcctttt
    15181 ccagtttacc atcaatagtg tagcgtttcc atcgtcctac acggtgacca ttcttatatt
    15241 ccccacattc acgaagctgg tcattcttta cataacgagc ttcgaacggt ccgttctgcc
    15301 ttccgttcac ataggtagaa gtttcccaat aatcaaagcg gttgctcact atcagccgtc
    15361 gttccttgcc atgcaatctg ccggcctgat aggtagcttc atatctcaat tcaccatttt
    15421 ccagattata ttcacggtat aaaccgtctt tacgatcgtt cttcatataa tattctttct
    15481 gccttacccc acttccgttg gcaaatgaga catggagtcc atcttctttt ccatccagat
    15541 aggtttcaat catcagcgta tctccgcttt cagcaaaagt agtccaccga ccattcttct
    15601 ttccattctt ataactaccc agtatacgtg gcgagccaaa cgtaaacagg gacgaatatt
    15661 caccgtcctg caaaccttct tcattgaaat aaacggtctc atacaaatca tatgtacctt
    15721 tcagaaaagt atactgtttg cctacctgct tcccgtcctt gtaattatgc tctttccgca
    15781 aagtaccgtc agattcgtac gacagttgct tcccgtgctc tttccccatc cggaagtttc
    15841 tttcactttc cacttttccg gtagtaaagt aacttttgct cgtaccatcc agcttacctt
    15901 ccttatagga cttttcttct ttcagcttac cgtcaaactt ggagttaatc ttgaagaggc
    15961 catccttccg cccttcttta taacttcctt ccgttattaa tatattgtcc acatattctt
    16021 tgtatccgcc atcataaaaa ccatctttaa aagatgccag cacataggcg gaatgataac
    16081 catctatgat gcgatgttcg ccattcaatg ctttttccgt tttcagttcc tgaaacaaca
    16141 gtctgccatc gcctacatta acaacagata cctgatcgat cttatattcc ttttgcgcaa
    16201 acaaaggaag agcaagatat aaaaacaaaa atacgttcca gctttttgat ctgaggaagt
    16261 tcgaaatgtg tttcataaag tagttttctc tttttgattt attatttaaa aacctgccgc
    16321 aaagataggc aatcggctta taaaacaagg caaggaagag ggggacaatt agaaaaaaga
    16381 acatctgtta ttatcattct aataattaac agattaagta gtaaatcaaa acacagggaa
    16441 gggggacatt tactgaaata agaaacagaa aagaagatgt gtcaaaagca actaaattcc
    16501 cctccttccc gaaggaggag agtttagttg cttttgacac accttctttt tgaatttaaa
    16561 gagattctac aacaatctgt ctttcagaat aaccggaagt tcgggcattg caccgctctg
    16621 cgtacaaaca taagcggaaa cttcgacagc cagcttatga gcttcgggaa cagacttgcc
    16681 attcagaatg gaagcacaga aagcggcagt aaaggaatcc cccgc
//
