LOCUS       gnlProkkaINFHEJLL_57   11421 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|INFHEJLL_57.
ACCESSION   gnlProkkaINFHEJLL_57
VERSION     gnlProkkaINFHEJLL_57
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:55:39
            Original ID  :: gnl|Prokka|INFHEJLL_57
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11421
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..885
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 34.7;
                     E-value: 1.3e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg57_1"
                     /transl_table=11
                     /translation="MAGGLKEAASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFV
                     IDGQPGFILEPYDQVYVRRSPGYQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGG
                     PTNYAYLRGAKLTRVANASEKKRMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEK
                     ALSNPKSNADLVLREGDVISIPKNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCS
                     DNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSL
                     GMMIASIANLIKK"
     protocluster    1..11421
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2107:6421]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2108..6421
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11421
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11421
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             896..2044
                     /locus_tag="ctg57_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             2108..2827
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.3e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.8e-17, bitscore:
                     52.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2848..4149
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 207.4;
                     E-value: 4.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_4"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 6.1e-121, bitscore:
                     392.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.9e-63, bitscore:
                     203.5, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKEGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             4166..5290
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5300..6421
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg57_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_6"
                     /sec_met_domain="Aminotran_5 (E-value: 1.8e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5390..6397
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg57_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg57_6_Aminotran_5.1"
                     /locus_tag="ctg57_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             6418..6894
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 70.3;
                     E-value: 2.9e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYSNIY
                     LGKNAEIRSGCYLIARDKIIIGENSTLAYGTTILTTADPNGPYNALAILYPYKKAPVVI
                     GDNVWIGANVTILPGITIGDYVVVAAGSVVTKDVPSGVLVAGVPAVVKKQLLME"
     CDS             6963..7784
                     /locus_tag="ctg57_8"
                     /transl_table=11
                     /translation="MKDKTCHIITDDNIKEIELSILKYIDLQCKKYNLRYYLGYGTLLG
                     AVRHQGFIPWDDDIDIWMPREDYDKFISLENSLENSKFKILSPLNNSDYYYGFAKLVSR
                     NTELQEIGFLPIKDYGVYVDIFPLDNIATEHPFLHFIAKYIIMARIASCNIKPWLNLTH
                     KKKAILFRFIGIIGTLLGFRRTAKLTDKIAKIDKGKTNKRVGVFVESIGEHNIFATEYF
                     ASTIQLKFEGIYFNAPKEYRKCLTQLYGDYMQLPPENRRISGHSFKACYRL"
     CDS             7769..8527
                     /locus_tag="ctg57_9"
                     /transl_table=11
                     /translation="MLQIMKLTTYVLNLLKDKERKEYMQYVLSDYPNLDIQYVNAINGK
                     NLSLDEILNQFDNNKAYKRYGRECDLGEIGCSLSHRLAFDLLMNSESNYALILEDDIVI
                     GDGFSSVLEKLLPLIDIDAPCVILLSGGVSYYKKRYYNTLCLGVVYMGDYAHSYLINKA
                     AAKLILDDKKAYIFADDWDYIRNRGVNVLVILPHLVDQRRDGSFVSNVWQDNHHIVKVK
                     LSLIRLCNYILSRIIDKILKRMGNYENKTL"
     CDS             8529..10064
                     /locus_tag="ctg57_10"
                     /transl_table=11
                     /translation="MVESRSKKGIANIKCSLFFYIVNLFLNIISRKVFIDYLGIEVLGL
                     NTTVTNLLSFLNLAELGIGNAIAFTLYKPLFLKDFQVIREIVSVQAWLYRRIAYFISIG
                     ALGLMLLFPVIFKKIDLPLWYAYATFIVLLIASLLSYFVNYKQILLSADQKEYKITLCV
                     QGIKSLKTITQVVVILYLINGYVYWLTLELVGVLVSALLLNKIVNKEYPWLFVKVSDGK
                     KLRNKYPEIIVKTKQFFFHRISSFVLNQTSPLIIYAFASLTMVAIYGNYMLIVFGGIAL
                     VNAFFNGFNAGVGNLVAEGDKKKIKSFFWEITSFRIWIAAIICVCFFKLCHPFISLWVG
                     KEYVLDEMTFIVLTIYVFISLTRVNEAFLFAYGLYQDIWAPIIEAILNLGLSVLLGFIW
                     GLTGIISGVVISLVVIVCIWKPYFLFKMGFKDNILEYVSRYIKYYMMIALSFILSHLIL
                     NTMFIDFQSSYWKLFEYACTVGSCYAILSFLFFYLFDNGMRQFTRRLLNIFLK"
     CDS             10134..11147
                     /locus_tag="ctg57_11"
                     /transl_table=11
                     /translation="MSFYIFIFVVLLYFSFRKYNKYIYWGTILLLSLIAGLRSETIGVD
                     THAYKDIFIWISNEVLYPIEPAWYFFNKLIAWVGGSFNFLLWITALLTLIPIGVVSLRC
                     SSNPQMSLFFYYGLYAYINSFNGMRQFVAISFVLLAYSYITQKKNFFLYLLIAFIFHYS
                     AIFSFIAILVDKVSLTKRRVIGGIFSSFFVGMFFNDSMFLVLAGPYAGYLESSEGYRDN
                     FLLAAIMAILMSCLYMCTFFTLRREYKQNLWTKMFFVGIIILNITMRLELGARIILYFT
                     LCQIIFYPMYFRHNIVKNKRMVVLSILLYTSLVFMKILILGNQGEYSVYPYKTILW"
ORIGIN
        1 caggccggtg gcttgaaaga agccgcctct actgtccgta ttgatatatc gagacgaatc
       61 aagaatcctc gtagtactgc ggataatgat acgattggtc agatgtatac cttctcttta
      121 aaggatggtt ttgtaataga tggtcagccc ggttttatcc ttgagcctta tgatcaggtt
      181 tatgtccgtc gcagtccggg ctatcaggca caacagaatg tagccattga aggtgaaatc
      241 cttttcggag gaaattacgc catgaccagc cgtgaggaac gtctttccga tttagtgaat
      301 aaagccggcg gtccgaccaa ttatgcctat ctgcgtggtg cgaaactgac ccgtgtggct
      361 aacgctagtg aaaagaaacg tatgggtgat gtaattcgcc ttatgagcag gcaattgggc
      421 gaagccatga ttgactcttt gggtattcgt gttgaagata cttttacggt tggaatagat
      481 ttggaaaaag ccttgagcaa tcctaaaagt aatgccgatc ttgtcttacg tgaaggtgat
      541 gtgatctcca tacctaagaa tactaatact gtaactatca atggtgctgt catggttccg
      601 aatacggttt cttatatgaa gggaaagaat gtggattatt acctgaatca ggccggtggc
      661 tgttctgata atgcaaggaa gagtaagaag ttcattgttt acatgaatgg tcaggtgacg
      721 aaggttaagg gtagtggtaa gaaacagatt gagccggggt gtgagattat tgtgcctggt
      781 aaggctaaga agaaagggaa catagctaat attttaggtt atgctacttc cttcagttct
      841 ttgggaatga tgattgcttc tattgctaat ttgataaaga aataaatgac ctattatgat
      901 tgaaaagcaa tcttatcaag aaccgttttc tgaagtggat aaaaggaaag atgatgaaat
      961 ggaaatagac ttgatggcta ttttttataa gattattact gttcgtggag tactatgcaa
     1021 agctgctgga gtgggagtaa taattgctat agtggtggca ttgagcattc ccaagcaata
     1081 tacagtaaag gttacccttt ctcctgaaat gggtaatgcg aagggaagta atggtttagc
     1141 cggacttgct gcctcgtttt tgggagatgg ggctctaata ggggaaagca cagatgcctt
     1201 gaacgcttct ctttcagcag atattgtttc ttcaactcct tttttattgg aacttttaga
     1261 aatggaagtc tccgtttcta aaaaggatga taaaatgact ttggggtctt atctcgatga
     1321 agagtcatct ccttggtggg attatcttat aggttttccg ggcatagtaa taggaggagt
     1381 taaatcatta ttcggagaag atacggttcc tgccagtgga gggcggcaag gaactatcga
     1441 attgacgaaa gaagtaaatg agaagattaa ttttcttaaa aagaagatta gtgcatccat
     1501 tgataagaaa accgccataa cgagcattac ggtcacctta caaaatccgc agatcactgc
     1561 ggttatagca gattctgtcg ttcataaatt acaggaatat attattgggt atcgaacttc
     1621 aaaagtaaaa gaagactgtg cgtatttgga acggttgttt aaagaacgtc agcaggaata
     1681 ttatgctgct caaagaaaat atgcggatta tgtagacgcc catgataatg tggttcttca
     1741 aagtgtacgt gctgagcagg agcgtttaca gaacgacatg agtttggctt atcagatata
     1801 tagtcaggtt gctaatcagt tgcaggtatc cagagccaaa gtacaggagg aaaagccagt
     1861 ctttgcagta gttgagcctg ccgttgtacc tttgaaacct tcaggtatgg gactcaaaat
     1921 ttatatttta ttatttgtgt tcctgtccgt atctggtact ctcgtgtggg tgctttttgg
     1981 caaaagtctg ctggctagct tgagaaaaga actgaaaaat aaggagatag aacaggataa
     2041 atgatgctaa aacgtcgttt acaacattct tacatcaatt aaattcactt actatattat
     2101 taaacgaatg atacgtacag ctatgataat ggctgcgggc atgggaaccc gttttggcca
     2161 atatacagaa ttgataccta aagggttcgt caaagtggga ggtattccaa tgatagttcg
     2221 ttctattgat actttgttat catgtggcat tgagcgaatt gtaatcggta caggatataa
     2281 acaagaagtt tatgaagaat tgaagacaga ctatcctatg cttgaaacct gttttagtcc
     2341 tcgttatgct gaaacaaata gtatgtatac tttatataat acgcgggaga ttctgggcaa
     2401 tgatgatttt ttattgttag agtcagattt gatttttgag aaacaagcaa taatgagctt
     2461 attggagtgt cctgcggcag atgcaatgct aataactcca gtgacaaagt ttcaagatca
     2521 gtattatgtg gaacatgatg ataattttcg cctttcttca tgttctgtca ataagaataa
     2581 actaaacgct aaaggcgaat tggtcggcat ccataaacta tccggttcct tttacaaaat
     2641 aatgtgtgct gattatgcga gtattgttga tgaacaaccc aatttgggat atgagtatga
     2701 attactacga atatcttgtt ctcaatctcc tgtttatgtg cataaagtag aagggctgaa
     2761 atggtatgaa atcgatgaca tatcagattt ggaatatgca gagaaatata ttgttccgta
     2821 ttgttaatta aaataatata tcaaattatg agtaagacag tttatattgg gatgactgcg
     2881 gatattatgc atccaggact tatccgcatt attaatgagg ctactaaata cggtgatgtt
     2941 ataattggtc ttcttacaga taaagctatt gcggagcata aacgccttcc ttatctgacc
     3001 tatgaacaac gaaaagaggt agttcagaat attaaaggcg tatgtaaagt tgttcctcaa
     3061 gaagaatgga gctatgttga gaatctcaaa cgcattaaac ctgactatat aattcatggt
     3121 gacgactgga aaaccgggcc tttacgtgaa gaacgtgtgc gcgtatttga agtgatgaat
     3181 gaacagggag gaaaggttat cgaaattcca tatactttgg gaattaattc atcttctttg
     3241 gataaagata ttaaggctat aggtacaacc cctgatgtac gtttaaaatc acttcgtcgt
     3301 ttgataaatg ccaaacccgt agttcgtatt ttggaagctc atgatggact atgtggcttg
     3361 ataattgaaa atcaggaaat attaaaaggg gataagaggg aagtatttga cggaatgtgg
     3421 tctagtagcc ttacggattc aaccagtaaa ggtaaacctg atattgaggc ggttgattta
     3481 actacccgat tgcaagattt gaataatatt ctggagtgta ctactaaacc tattattttt
     3541 gatggagata caggtggtaa aattgaacat ttcgtattta cagtacgcac tttagaacgt
     3601 catggaattt cagctataat aattgaagat aaagttggat taaaaaagaa ttcattgttt
     3661 ggtacagatg ttattcaaac tcaagataca atcgaaggtt tctgtaataa gatcaaagaa
     3721 ggaaaggcat ctcagattac tgatgatttt atgattatcg ctcgtattga gagccttata
     3781 gcgggaaagc cggtaagtga tgctttagag agagcttttg catatgtcca agcgggagcg
     3841 gacggtatta tgatacatag caaaaataag tcgggtgaag atataaaaga attttgtttg
     3901 gcgtttcgaa aacagtatgc tcatgtacct atcgtggttg tgcctactac atatgatcat
     3961 atttatgagt ctgaattgtg tgattggggt gtgaatataa ttatttatgc taatcatatg
     4021 cttcgtgccg cttatcctgc tatgatgaat gtcgcaaaga caatattaga gaatgaacgt
     4081 gctttagagg tgcgcgaact gtgtatgccc ataaaagaaa tattggaact gattccaggt
     4141 actaaataaa aagaggaata tcattatgtt aagcgtagaa aaagtttatg aaacgtttct
     4201 gagtcatgac gttgattttt ttacaggagt tccagactca ttactaaaaa atatttgtgc
     4261 ctatatcaca gaccatactt cacgtgagaa acatatcata gctgctaatg aaggtgcggc
     4321 tgtaggaatt gcttcaggtt attatatggc atcaggtaag gttcctgtgg tttatatgca
     4381 aaattccggc ttgggtaata ctgttaatcc tctgctgtct cttgcagatg aacaagtata
     4441 cagttttcca atgcttttga tgattggctg gcgtggtgaa ccgggaacaa aagatgaacc
     4501 tcagcataaa aaacagggtg aggtaacttt agatttgttg aaagcaatgc ggattcctta
     4561 tataattctt gattcaaatg agaatgatgc atttattcag ctccatgata tcatacaatc
     4621 agcaaaaact aagaatattc ctcatgcaat aattattcgg aaagatgttt ttggcaaata
     4681 taaacttcaa aaagagtttg gatgtaatta tcctttatct cgtgaggatg ctttgcaaat
     4741 agttgtggat tatctgcctg aaaattcagt ggtcgtttct actactggca agctttctcg
     4801 tgagttattt gaatatcgag aaatgaaaga gcaaggtcat gaacatgatt ttctcacggt
     4861 aggctctatg ggacatagtt catcaatctc tttgggtatt gctatagcaa agcaagatag
     4921 acctgtttat tgcttggatg gtgatggagc atttattatg catttagggg caattagtaa
     4981 cattggcgat ttatctccta aaaactatta tcatattttg tttaacaatg gtgctcacga
     5041 gtctgtagga ggacagccta ctttaggatt tagtttagat attccggcta ttgtccgggg
     5101 gagcggatat aagcatactt atactgtttg tacaaaagtt gaaattgaag aagcaatgaa
     5161 gcagcttcca aagttatgtg gtcctgtttt gttggaaata aaggttaaaa tagattctcg
     5221 ggagaatttg ggacgtccca cgactactcc tatagagaat aaggagcatt ttatggattt
     5281 tttaaaataa atatattcga tgaaaataga aagaaaaata ttattaaatc ctgggcctgc
     5341 cactactact gacagtgtaa aaatggcaca agttgttccg gatatttgtc ctcgcgagaa
     5401 agaattcgca ggtatgatga aacaacttcg ggacgatttg gtcagagttg ctcatgggaa
     5461 tttggaaaaa cataccgctg tattattttg tggctcagga accatcaata ttgatatatg
     5521 tctaaattct cttcttcctg aagacaaaag ggtgcttata gtgaataatg gggcatatag
     5581 tacccgtgct gtagaagtgt gtcaatatta tggtttgcct catattaatt tggaattttc
     5641 cgtttatgaa cgtcctgatt tatcggtggt ggaaaatgtg ttgcaagaaa atcctgatat
     5701 agctatggtt tatactactc atcacgagac gggtacagga attctgaacc ctattcgcga
     5761 gatgggcgct atagctcata aatatcaggc taaatttgtc gtcgatacta cttcttcttt
     5821 gggcatgatt ccttttgata tagagaaaga taatgtggat ttttgtatgg catctgctca
     5881 aaaaggactt caagcgatga caggtctttc ttttattata ggcaatgagg aacagattaa
     5941 gttttcaaaa aaatatccca agcgttctta ctattgtaat ctttatttgc agtatgagaa
     6001 ttttgagaga acaggtgaaa tgcattttac tccaccggta caaactattt acgccactcg
     6061 tcaggcatta aatgaatatt ttgaagtggg cgaagaagct aagtttgccc gtcacaaaag
     6121 agtttttgag gctattcatt caggtataaa tgaaattggt cttaaaagtg taataaagcg
     6181 tgaatggcag tcaggactgg ttgtctcagt tcaataccca gaagatccca actgggattt
     6241 tgagaaaata catgattatt gttatgagcg tggatttacg atttatccag gtaagatatc
     6301 aactgaggat acttttagaa tctgtgcttt aggagagata gaagtagatg atattgagaa
     6361 cttctttaaa gtactaaaag ctgcattaaa tcattataac gtcacattac cgatgtcatg
     6421 attgcagaaa tattattgaa gattcgtcat ttttattttt cccttcgtgg tatacacttc
     6481 catccggaaa gtgttatttc tggagtgcct attcgtagct ttcgcttagt aggcaaatat
     6541 agcaatatct atttgggtaa aaatgctgaa atacgttcag gctgttatct gattgctcgt
     6601 gataaaatca ttattggaga aaactcaaca ctcgcctatg gaacgactat attgacaact
     6661 gctgatccta atggaccgta taatgcatta gcaattcttt atccttataa aaaggcaccg
     6721 gtagttatag gagataatgt ttggattggg gctaatgtta ccatccttcc tggaataact
     6781 attggtgatt acgttgtagt agcagctgga tctgttgtaa caaaagatgt accttcaggg
     6841 gtattggttg ctggtgtacc agctgttgtg aaaaaacagc ttttgatgga ataagaataa
     6901 ttgttttatt cttattgtca gacaatatca ttacataaga agtataattt aatgcctcaa
     6961 taatgaaaga taaaacttgt catataataa cagatgataa tataaaagaa atagaattat
     7021 ctatattgaa atatattgat ttacaatgta aaaagtacaa tctaaggtat tatttgggat
     7081 atggtacttt attgggagca gtgcgtcatc aaggtttcat tccttgggat gacgacattg
     7141 atatctggat gccacgggag gattatgaca aatttataag tttagaaaat tcattggaaa
     7201 actcaaagtt taagatttta tctcctttga acaattcaga ttattattat ggatttgcta
     7261 aactagtatc aagaaataca gaacttcagg aaataggatt tcttcctatt aaggattatg
     7321 gtgtatatgt ggatattttt cctttggata atattgcaac ggagcatccg tttttacatt
     7381 tcatagctaa atatataata atggcaagga ttgcgtcttg taatataaaa ccttggttaa
     7441 atctgacgca taagaaaaaa gctattttat ttcgctttat aggaataatt gggacattgt
     7501 taggatttcg aagaacagca aaattaacgg ataagatagc taaaatagat aagggtaaaa
     7561 cgaataaaag ggtgggggtc tttgttgaaa gcataggaga gcataatata tttgcaacag
     7621 aatattttgc ttctacaata cagttgaaat ttgagggaat atattttaat gctccaaagg
     7681 aatatcgaaa atgtttgact cagctttatg gagattatat gcaactacct cccgaaaata
     7741 gacgcatttc tggtcattca tttaaagcat gttacagatt atgaaactaa caacatatgt
     7801 tcttaattta ttgaaagata aagaacgaaa agaatatatg caatatgtat tgagcgatta
     7861 tcctaatcta gatattcaat atgttaatgc aataaatgga aaaaatctta gtctggatga
     7921 gatattgaat caatttgata ataataaagc atacaaacgc tatggaagag aatgtgattt
     7981 aggagaaatt gggtgcagtt tgagtcatcg attggcgttt gatttattaa tgaattcgga
     8041 gagtaactat gctttaattt tagaagatga tattgttatt ggggatggat ttagtagcgt
     8101 attggaaaaa ttattgccat tgattgatat cgatgctcct tgtgttattt tattgtcagg
     8161 tggtgtctct tattataaaa aaagatatta taatactttg tgtttgggtg tagtttatat
     8221 gggagattat gcgcatagtt atttaataaa taaggctgct gctaaattaa tattggatga
     8281 taaaaaagcg tatatatttg ctgatgattg ggattatata cgtaatagag gagtaaatgt
     8341 actagttatt ttacctcatt tagttgatca acgtagagat ggaagttttg taagtaatgt
     8401 ttggcaagat aatcaccata ttgtgaaggt gaaattatca ttgattaggt tgtgtaacta
     8461 tattctttca aggataatag ataaaatatt gaagcgaatg ggaaattatg agaataagac
     8521 actgtagtat ggttgaatca cgttctaaaa aaggtatagc aaatataaaa tgttctttgt
     8581 ttttttatat cgtaaactta tttcttaata ttatatctag aaaggtcttt atcgattatt
     8641 taggaataga agtactagga cttaacacaa cagttactaa tctgcttagt tttctaaatt
     8701 tggcagaatt gggaattggt aacgcaattg catttacttt atataaacct ttatttttga
     8761 aagattttca agttataagg gagatagtgt ctgttcaagc ttggctttat cgacgaattg
     8821 catattttat atctataggt gctttaggac taatgttgct ttttcctgta atttttaaaa
     8881 aaatagattt acctttgtgg tatgcttatg ctacatttat tgttttattg atagcttctt
     8941 tgttgagcta ttttgtgaat tataaacaga tacttctaag tgcagatcaa aaagaataca
     9001 aaataacact ttgtgtacag ggaataaaat cattaaaaac cataacacaa gtggttgtta
     9061 tattatatct aataaatggg tatgtgtatt ggttaactct tgaacttgtg ggggtattgg
     9121 tttcagcttt gctattaaat aaaattgtaa acaaagaata tccttggttg tttgtaaagg
     9181 tctctgatgg aaaaaaatta cgtaataaat atccagaaat aatagtaaag acaaaacagt
     9241 ttttttttca tcgcatctca tcatttgttt taaatcaaac tagtccattg ataatctatg
     9301 cctttgctag tcttacaatg gtagcaatct atggaaatta tatgttgata gtttttggtg
     9361 gaatagctct ggtaaatgct ttttttaatg gtttcaatgc tggagtggga aatcttgttg
     9421 ctgaaggaga taagaaaaaa ataaaatctt ttttttggga aataacttct tttcggatat
     9481 ggatagcagc catcatttgt gtctgttttt ttaagttgtg tcatcctttt atttcattgt
     9541 gggtgggaaa ggaatatgtt ttggatgaaa tgacctttat agtgttaact atttatgttt
     9601 ttatatcatt aacaagagta aatgaagctt ttctatttgc ttatggatta tatcaggata
     9661 tatgggctcc tataattgaa gctatattaa acttgggact ttcggtttta ttgggattta
     9721 tttggggact aacaggaata atatctgggg ttgttattag tttagttgtc attgtatgta
     9781 tatggaaacc atatttttta tttaaaatgg gtttcaaaga taatatatta gaatatgtct
     9841 ctagatatat aaaatattat atgatgattg ctttatcttt tattttgtca catttaattc
     9901 ttaatacaat gtttatagac ttccaaagtt catattggaa gctttttgaa tatgcttgta
     9961 ctgttggaag ctgttatgct atattgagtt ttctcttttt ttatttattt gataatggga
    10021 tgagacaatt tactagacgt ttattaaata tatttctaaa ataatttagt gataaggtgt
    10081 agttgttata tttagttttt agctgaaata gattttgtct tgtattataa aaaatgagtt
    10141 tttatatatt tatttttgtt gttttgctgt atttctcttt taggaaatat aataaatata
    10201 tttattgggg aactatttta ttactttcat tgatagcagg gttgaggtcc gaaacgatag
    10261 gagttgatac tcacgcttat aaagatatat ttatatggat atcaaatgaa gtattatatc
    10321 cgatagaacc tgcatggtat ttttttaata aattgattgc ttgggtgggg ggaagtttta
    10381 atttcttgtt gtggataact gcactattga ctttaatacc aataggtgta gttagtttac
    10441 gatgtagcag taatcctcag atgagtttgt ttttttacta tggattatat gcatatatta
    10501 attcatttaa tggaatgaga cagtttgttg ctatttcatt tgtattatta gcttattctt
    10561 atatcacaca aaagaagaat ttttttttgt atttactaat tgcattcata ttccattatt
    10621 cagcgatttt ttctttcatt gctattttgg tagataaggt atcattaact aaacgacgtg
    10681 taattggtgg tattttttct agtttttttg taggtatgtt ttttaatgat tctatgtttc
    10741 tagttttggc tggtccttat gcaggttatt tagaatcttc tgagggatat agggataatt
    10801 ttttattggc tgctataatg gcaattttga tgagttgttt atatatgtgt acgtttttta
    10861 ctttacgaag agaatataaa caaaatttgt ggacaaaaat gttttttgtt ggcattatta
    10921 tattgaatat aactatgcgg ttagaattag gagctcgtat tattttgtat ttcacattat
    10981 gccaaattat attttaccca atgtatttcc gtcataatat tgtcaaaaat aaaagaatgg
    11041 ttgttttgag tattttattg tatacttcgt tggtttttat gaaaatatta attttgggta
    11101 atcaaggaga atattctgtc tatccttata aaacaatatt atggtaagca ttattattcc
    11161 ttgttacaat tcgggaaaat atatttctga atgtttaaat tctattttag ctcaaacata
    11221 ttctgaatgg gaagcaattt gtgttaatga tggtagtact gataatacaa tggaatttct
    11281 gaatcaatat gtaatgtcgg ataatcgata taaagtagtt tctcagctta attcaggagt
    11341 gtcagcagca agaaataagg ctttatctat atgcaggggg gaatatattt gctttgtaga
    11401 tagtgatgat atagtagaac c
//
