LOCUS       c00022_gnlPro..        13675 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NHEOKJJA_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:15:37
            Original ID  :: gnl|Prokka|NHEOKJJA_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13675
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13675
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[702:3675]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      703..3675
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13675
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13675
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             703..2931
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_1"
                     /sec_met_domain="Gly_radical (E-value: 5.5e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2947..3675
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="Radical_SAM (E-value: 4.8e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(3703..4146)
                     /locus_tag="ctg22_3"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVSELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(4133..4324)
                     /locus_tag="ctg22_4"
                     /transl_table=11
                     /translation="MITLILDQMKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATH
                     KEVCNVKTTEREKDDEKD"
     CDS             complement(4321..4824)
                     /locus_tag="ctg22_5"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             5018..5248
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="MYYPDQPFHICTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             5336..7453
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MEHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPIFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHASLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRILQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSSTYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPNNKDDLAKIAQAMLINLDEFEGMNGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVNSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(7542..7673)
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="MVGNLKKITVFFKFPTVFLRKKKEKVRVGEGKFLTFVFFFRRK"
     CDS             complement(7696..8061)
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MTKIENQTQYEWAVKRVEDLLPLVKDDTPLNDPNSIELELLSNLV
                     ADYSEEHFSLGEPSLVDVLKLRMYEMGLNQKSLSQLIGVSPSRLSDYISGKCEPTLKVA
                     REISKKLNIDASIVLGV"
     CDS             complement(8066..8359)
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="MRIFTEQALKEYAEEHPDSKVALQEWVTIVKKSEWACFADIKKTF
                     NSADSVGNQHYVFNVKGNNYRLVVVVKFTVKFVYIRFIGTHKEYDKIDCANI"
     CDS             complement(8457..8759)
                     /locus_tag="ctg22_11"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLDAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             complement(8725..9078)
                     /locus_tag="ctg22_12"
                     /transl_table=11
                     /translation="MEKKRKIRTYGGYFEAFMETLTEKEQDKIQYGLLLLKTQERLSTK
                     FVKFVQDGVFELRTEYNGNIYRVFFIFDDGNIVVLFNGFQKKAQKTPGSEIDKALKIKE
                     EYYADKQSSNSRL"
     CDS             complement(9135..9380)
                     /locus_tag="ctg22_13"
                     /transl_table=11
                     /translation="MSHLTPVIIEYRGNPKQYVSVVLDAINLGRLTYDGVANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             complement(9389..9523)
                     /locus_tag="ctg22_14"
                     /transl_table=11
                     /translation="MENSLNDELLCSLKDELREVTAQINVHSEKLMDLLDQKKESSVN"
     CDS             complement(9650..11005)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 152.3; E-value: 5.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_15"
                     /sec_met_domain="MFS_1 (E-value: 1.2e-46, bitscore: 152.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKQLINFYKVSSPRPCNGETLSSSDARRLKFLKWSTFLSATFGY
                     GMYYVCRLSLNVVKKPIVDEGIFSETELGIIGSVLFFTYAIGKFTNGFLADRSNINRFM
                     TTGLLVTALVNLCLGFTNSFILFAILWGISGWFQSMGAASCVVGLSRWFTDKERGSYYG
                     FWSASHNIGEALTFLIIASIVSVLGWRYGFFGAGIVGLIGALIVWKFFHDTPESMGFPS
                     VNVPKQKKEMSETETADFNKAQRQVLLMPAIWILALSSAFMYISRYAINSWGVFYLEAQ
                     KGYSTLDASFIISICPVCGIIGTMFSGVISDKLFGGRRNVPALIFGLMNVFALCLFLLV
                     PGAHFGIDVLAMVLFGLGIGVLICFLGGLMAVDIAPRNASGAALGVVGIASYIGAGLQD
                     VMSGILIEGQKTVQNGVDVYDFTYINWFWIGAALLSVLFALLVWNAKSKEMD"
     CDS             complement(11019..11912)
                     /locus_tag="ctg22_16"
                     /transl_table=11
                     /translation="MRKLFIFSLLLIAISGINAQNRKLRANLLDKNNHSVMVVSHRGDW
                     RNAPENSLQAIQNCIDMGVDMVEVDLKKTKDGHLIVMHDQTIDRTTTGKGKPENYTLEE
                     LRRFRLKNGAAHKTTHLIPTLEEVMLLCKGKILVNIDKGYDYFKEAYCILEKTGTVDQC
                     VIKAGLPYEQVKVENGEVLDKVIFMPVINLNKEDAEKIIDSYQKHLKPIAYELVFDNDE
                     KETLRLIQKVRDSGARLFVNSLWPKLCGGHDDDRAVELHQPDESWGWIIAQGAKLIQTD
                     RPALLLEYLRNKKLHD"
ORIGIN
        1 caatcgtttg ggaagaggat gttttcatga tgcaaaaata agaattttaa cgcaatcccc
       61 caaggtttca gactgagccg gtttcagact gagcctttgt tgtcttggaa acaagactta
      121 taggcaataa aaaaacctac aaatcgctga tttgtaggtt tttgacctct tannnnnnnn
      181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nntttgttgt cttggaaaca agacttatag
      301 gcaataaaaa aacctacaaa tcgctgattt gtaggttttt gacctcttac tgtcctattt
      361 tgtccagtag gttctgcgga gagacaggga ttcgaacccc gggtacctcg cggtacaacg
      421 gttttcaaga ccgccgcaat cgaccactct gccacctctc caaaacttcc ttttcagaag
      481 tgctttttgt taaaagcggt gcaaaggtac gaatatattt taaacttgca agagttttca
      541 caaaaaaaaa tcacgaacat catttccaaa gaatagctat atctaggtat tttatgttga
      601 aaagcataaa atacagcata tttatgctga ttatatgaaa aaacgttgta actttgtgcg
      661 ctctaaagaa aaggataact acaacctcta attttatcat ttatggaatt aaataagatc
      721 tttaaagacg gtctttggag cacagaaatc aacgtaagag atttcgttag tcacaacatc
      781 actccgtatt atggagatgc ttctttcctc gaaggaccta ccgaacgcac taaagctgta
      841 tggaaccgct gcctcgaagc actggcagaa gaaagagcca ataacggagt acgctcactg
      901 gataatgtca ccgtctcaac catcacttct cataaagccg gatatatcga caaagaaaac
      961 gaactgatcg tcggtctgca aacagacgaa cttctgaaac gtgcaatcaa acctttcgga
     1021 ggtatcaacg tggtgagcaa agcctgccac gaaaacggcg tggaagtgga cgaccgtgta
     1081 aaagatatat tcactcacta ccgcaagacg cacaatgacg gagtatttga cgtatatacc
     1141 gaagaaatcc gttcgttccg ttctctggga ttcctcaccg gacttcctga caactatgcc
     1201 cgcggacgta tcatcggcga ctaccgccgt atggctctct atggtatcga ccgactgatt
     1261 gaggcaaaaa aagaagattt gcgtaacctt accggtccga tgaccgaagc ccgcatccgc
     1321 ctgcgcgaag aagtggcaga gcaaatcaag gcattgaagg acatgaaggt aatgggcgaa
     1381 tactacggac tcgacttgag ccgtcctgcc tacaccgcac aagaagcagt acaatgggtg
     1441 tacatggctt accttgctgc cgtaaaagaa caagacggtg ctgccatgtc actgggtaac
     1501 gtctcttcgt tcctcgacat ttatatggaa tatgaattga gcaaaggaac tatcacagaa
     1561 tctttcgcac aggagctgat cgaccagttt gtcatcaaac tgcgtatggt gcgccacctg
     1621 cgtatgcaat cttacaacga catctttgcc ggcgacccga catgggtaac cgaatccctg
     1681 ggcggacgcc tcaacgacgg acgcaccaag gtgacaaaga cttctttccg cttcctgcaa
     1741 acactctaca acctcggccc ttcaccggaa ccgaacctga ctgtattgtg gagcccggaa
     1801 ctgccggaag gattcaaaga attctgcgca aaagtatcta tcgacacttc ttccatccaa
     1861 tatgaaaacg acgacctgat gcgtgaagtg cgccagtctg atgactacgg aatcgcgtgc
     1921 tgcgtatctt atcaggaaat cggaaaacaa atccagttct tcggcgcacg ttgcaacctg
     1981 gctaaagccc tgctgcttgc catcaacggc ggacgttgcg aaaacaccgg tacggtaatg
     2041 gtgaaaaaca tccccgtact aaccagcgac acactgaact tcgaagaagt aatgagcaac
     2101 tacaagaagg tattgacaga aatcgcccgt gtttacaacg aagcgatgaa catcatccat
     2161 tatatgcatg ataagtatta ctacgaaaaa gcccaaatgg ctcttgtaga taccaaccca
     2221 cgcatcaacc ttgcttacgg tgtagccgga ctttctatcg ccctcgattc actgtcggcc
     2281 atcaaatatg ccaaagtaac cgcacgccgc aacgacatcg gtctgacaga aggtttcgat
     2341 attcaaggcg aattcccttg cttcggtaat gacaacgaca aggtagacca cctgggtgtt
     2401 gacctggtct atttcttcag cgaagaattg aagaaacttc cggtttacaa aaatgcccgt
     2461 cctactctgt ctttgctcac catcacttcc aacgtgatgt atggcaagaa gacaggtgct
     2521 actcccgacg gccgcgccaa aggtgtcgct tttgctccgg gagccaaccc tatgcacgga
     2581 cgtgacaaga acggtgccat cgcctctttg agttccgtag cgaaattacg ttaccgcgac
     2641 tcacaggacg gtatcagcaa caccttctcc atcgttccga aatcactggg agctactgaa
     2701 gaagatcgcg tagaaaatct ggtgacaatg atggatggtt acttcaccaa aggcgctcac
     2761 cacctgaacg tgaacgtact gaaccgtgaa atgctttacg acgccatgga acatccggaa
     2821 aaatatccgc aactcaccat ccgtgtttcc ggttatgccg taaacttcgt gaagttgagc
     2881 cgcgaacatc aattggaagt tatcagccgt agcttccacg aacgtatgta atcagatcta
     2941 ctcaatatga cgataaacgt acattcatac gaaagtatgg gaacattcga cgggccgggc
     3001 ttacggctcg tcgtttttct tcaaggatgc aatttccgct gcctgtattg tgccaacccc
     3061 gacacgatag ccggaaaagg aggcacacct accccaccgg aagaaatcgt ccgcatggct
     3121 atgagccaac gtcctttttt cgggaaacgc ggaggagtca ctttctccgg aggagaacct
     3181 acgtttcagg ccaaagcact agtcccttta gtgcgtgaac tgaaagaaaa gggaatacat
     3241 gtatgcatag acagcaacgg cggtatctgg aacgaagaag tagaagaact tttcaaactg
     3301 acggatcttg tattgctgga tattaaagag ttcaatccgg cacgccatca agcactgacc
     3361 ggaagaagta acgagcaaac catccgcacg gcagcatggc tggaagaaaa cgagaaacct
     3421 ttctggctgc gttatgtatt agtgcccgga tacagcgatt tcgaagagga tatccgccgc
     3481 ttgggagagg ctctgggaaa atataagatg gtgcaacgag tggaaatcct gccttatcat
     3541 acattaggcg tacataagta tgaagcgatg gagcaggaat acaagctgaa agacgtaaaa
     3601 gaaaataccc ccgaacaact tgaaaaagcc gcggaggtat ttaaagagta tttcactact
     3661 gtggtggtca attaaccacc acagtaataa ataggataaa aatcaccatg tctctgcttt
     3721 cacctcaaaa cagggacatt ctttgatccg ttcccagggg tctacaattc cgttgtagtt
     3781 ggtgtcaggg ctcaagtccc ggtgaccgac cacctttgca tccggataac gctgcaacaa
     3841 ctcgcttacc agacgatgca tcgcctcttt ctggcgggaa gtacgtgtat ccgctgcctt
     3901 tccgttctca tccagcccgc cttcatagca cacccctaaa ctaatcgcat taaaaccgcg
     3961 tgcatgagca cccaccgtat cttcatccct catcggttct atctgtcccg acttgcggat
     4021 ataataatga tacccccaac acgaaaagcc ccgaaagcga tgggcagtgt ccacatcctt
     4081 cgccgtgaag tcgcgatcga cacgggtagc agagcagtga atcacaatca gactaatctt
     4141 tctcatcgtc cttctccctt tccgtcgttt tcacattaca cacttcctta tgggtagcat
     4201 tgaagcgcac ctctctcaca attctgttcc gctttctttt tccgaagaaa ggcacaagga
     4261 acatgattac atccaaaatc ttagttacaa tttctttcat ttgatccaat attaaagtta
     4321 tcatgctgcc ggatccggag cttctccgct tccaccaccg tctgaaccac caccggaacc
     4381 tttgtcatcg tcttctcctt cattgccgct accgcccgtt tgagccaccg cacgcgtcgt
     4441 tacctgctgg tagctaagaa tcttcgtgat gtccgccaac gtctttccgg gacggaaaat
     4501 aatatgggca gccgtaatca gcgaacttga aaactccttg accgacacag ctccttcact
     4561 gttcaacccg atctgcaaac tgcccaaatc acccagccgg actattcttc ccgctttcaa
     4621 cgcacgcttc gcctcataaa gaatacccga aatggcggca cgcacatctg tctccgtaca
     4681 ggtagaccga ctcgtgattc cctcgcacaa ctcttcaaaa tccaactctc ccgaagcctg
     4741 tgcctgcgcg taatactttg ccgactcatc ctttttggca ggattcttgc gcggcactac
     4801 tgaataagtt actgtcattg ccataataaa ataattttaa gatttcacac atttcgaacg
     4861 cgttccttat ttgttaacga cataaagata acacattttt caccctccgg attccccaac
     4921 gaagtttcct gatactctat gaataataat gacgttattc ttttattaaa ccattaattt
     4981 tcagtaactt tatagcataa accaaatatc attcatcatg tattatccgg atcagccgtt
     5041 tcatatctgc acttataaaa agtcggaact agctcatctt tacaacccca acgtatgcct
     5101 taaagtagcc ttacaaatac tacgtcgttg gattgtctac aaccttccgc tcctgcaaga
     5161 actcgaacaa gaaggctatc gtgcccgcaa ccgccttctc tctccccggc aagtggcaac
     5221 gatcatacgc tatttgggag aaccctagga acttaatcaa aaaaacgaaa agttccattc
     5281 tattatttta caaacaaatt tctttgcaac cgcaaattaa aaagaacaaa ccaacatgga
     5341 gcattttacc atctttcaag acttttaccg cgtcatagcc gaaatgacag aagaagaaat
     5401 cgtatcggcc atcagcaacg gcacataccg ggaaacagtg gaggacgtgc gccgaatctt
     5461 cgcggaacaa ggcgagaaag cagcaaacga aaagaaaata gaactaccgg aaatcacctt
     5521 ttcagccaac taccggggag gacgttcaaa cgcaactctc gtcaagtatc tgggatacat
     5581 cgtggtagac atcgaccatc agacacagga agcattggca cgcatcctcg cactggcaaa
     5641 aaagtgtgcc cacacccgca tcgctttcat cagtcccaaa ggaatgggac tgaaaatcgt
     5701 ggtacgtgta tgccggacgg acgggacatt gcccgaaacg attcaggaaa ttgaagattt
     5761 ccatcatgcc gcttatcaca aaatcgcttc cttttatgcc cagctctgcg gagttgaggt
     5821 cgacacttcc ggacaagatg tcagccgtac ttgcctgttc tcttacgatc cggatattta
     5881 tttcaatccc gatgccacag ctgtcatcgt ggaacagcca ccgatattct tcaagtctca
     5941 aaagaagaaa agggcatccg gcaaaaagaa aaagacgaca gcaccagaca acaatcccct
     6001 caccgaacaa gtggcactca actaccattc ctcgcacgct tccttaatgg tgactctgaa
     6061 ctattatcac aataaatccg aaaagtacgt caccggcaac cggaacaact acctgcattg
     6121 cctggcttgt atgtacaatc gctacggcgt cccccaggaa gaggcggcag cttttatcaa
     6181 gagccagttc accgatcttc ccgcggatga aatggacgca ctgatcggga gtgcttacgg
     6241 acacaatgag gaattcgaca cccgcaagct gaatagtacg cagaagcgaa tattacagat
     6301 tgagcaacat atcaaagaaa attacgatac acgctacaac gaagtgcttc atatcatgga
     6361 atatcgcaga aggaaaacgg acacggagca accggaacct ttccatattc tcgacgaaat
     6421 gatggaaaac agcatttgga tggagatgaa cgaactgggc tattcgtgca ccgtcaagac
     6481 gattcagaat ctgatctact ccgacttcag cagcacctac catcctattc gcgagtattt
     6541 agactcgctg cctgaatggg acggaacgga ttatatcggt atccttgcca acagcgtgca
     6601 tactagtcac cagaaatttt gggtagaatg tctggaacgt tatctggtgg gaatgtgcgc
     6661 tgccgccacg caagacgatg tggtgaacca cactgttttg ttgctttgca gcgaaataca
     6721 gaacatcgga aagactacgt ttatcaacaa cctgctgccg cccgaattgc gcgcctatct
     6781 ttctaccggt cttattaacc cgaacaacaa ggatgatctg gccaaaatag cgcaggcaat
     6841 gcttatcaat ctggatgagt ttgaagggat gaacggacgg gaactgaata tcttcaagga
     6901 tttggttacc cgcaaagtaa tcagcatccg cctgccatac gcgcggcgtt cacagaactt
     6961 ccctcacacg gcttcttttg ccggcacatg caattatcag gaagtgcttc acgacaccac
     7021 aggtaaccgc cgttttctct gctttcatgt caactcgatg gagtttatca aaataaacta
     7081 cgcgcagttg tatgcacaaa tcaagtatct gctcaacaag ccggggtatc agtattggtt
     7141 cacccaatcg gaaaactcac ggattgaaga gaacaacgag gatttcattt tccactcacc
     7201 ggaagaagaa ctggtgttga cacatatccg caaaccggaa cgtttcgaaa aggtgcatta
     7261 tctgacggtc actgaaattg cggaattgat tcgcgaacga acggggtatc aatattctca
     7321 cggaaccaaa gcccaactag gaaaagtgat gtccaaacac ggcttcgaat ttcataaggg
     7381 aaaaaacggg agaagataca ctgtattcat tattgatacg gaacaggtga aatcaaacag
     7441 gctatatgaa taagatttca tctccttcgc acgcaaaaag gtgagggttg gtgagggtac
     7501 ttttgcaact tttcattttt atatttctta tttctattct tctattttct tctaaaaaaa
     7561 aatacgaatg ttagaaattt accctcacct accctcacct tttccttttt cttcctcaaa
     7621 aaaacggtgg gaaatttgaa aaagacagtt atctttttca aatttcccac catgtttttt
     7681 taatctgaat cgaagttata ctcctagcac aatactagca tcaatattca gttttttact
     7741 tatttcacga gccactttca atgtcggctc acattttccg gaaatgtagt cactaagacg
     7801 cgaaggacta actcctatca gttgtgatag tgatttctga ttgagcccca tttcgtacat
     7861 acgaagcttc agaacatcca caagcgaagg ttctcccaaa gaaaagtgtt cctctgaata
     7921 atcggcaaca agattagaaa gaagttccaa ctcgatgctg ttagggtcat tcaaaggagt
     7981 atcatccttc actaacggaa gaagatcctc cactctcttt acagcccatt catactgggt
     8041 ttggttttct atctttgtca tattttcaaa tattagcaca atctatttta tcatattctt
     8101 tatgagtacc aataaagcga atatatacaa actttacagt gaacttcacc actactacca
     8161 agcgataatt attcccttta acattgaaaa cataatgctg gttacctaca ctatcggcac
     8221 tattaaaggt cttctttata tcagcgaaac aagcccattc acttttcttt actatagtaa
     8281 cccattcttg caaagcaact tttgaatcgg gatgctcctc tgcatattct tttaacgctt
     8341 gttctgtaaa tattctcatt agttactcac ttatcatgca acaaaaataa gaatataatt
     8401 ccaattttca aaattatatt ccgatatttg taattatgga taaaaagatt cgcttcttat
     8461 aaagacatcg aaaattcgat cctacaacct aacgcattca tgatgcgata gaaggtagaa
     8521 accttaggtt ctgtctgacc actttccact cttgaaatat aagaacggtc ggaaccgata
     8581 cgccgggcta actctgcttg agtaatctta gcctttttcc ttgcgtcttc gataatttgc
     8641 ccggtgtaga aagcatacgc tttttcttct gcttccgcac gttcgggagt accttctgct
     8701 ccaaatttcg catcaagaac agcgtcataa tctactattt gatgattgtt tatctgcata
     8761 atattcctcc tttattttta atgctttatc tatttcacta cccggtgttt tttgcgcctt
     8821 cttttgaaag ccattaaaca acactacaat atttccatca tcaaaaatga aaaatacccg
     8881 gtatatatta ccattatatt ctgtacgaag ttcaaaaact ccgtcctgaa caaattttac
     8941 aaatttagtg gagagtcttt cttgtgtttt caacaagagt agtccatact ggattttatc
     9001 ttgttccttt tcggttaaag tctccatgaa agcctcaaag taacctccgt atgtacggat
     9061 cttacgtttc ttttccatac tgcaaatata cgaattgttg ttcaactata caacaatcgt
     9121 ctttttattt tatattattt ttcctcaaat tctccagcac gctttttctt ctcataagac
     9181 accagcgtct ctacactaag cgttttccca ttcttagggc ttatcacatc tacaacgctt
     9241 gctaacgcac gaaaagtctg ttcgcaattt gctactccgt catacgtcaa cctacccaga
     9301 ttgatggcat cgagcacaac agagacatat tgcttcggat ttccccgata ctcgatgatg
     9361 acaggcgtga gatgcgacat ctctcgagtc agttgactga cgattctttt ttttggtcga
     9421 gcagatccat taatttttca ctatgcacat tgatttgtgc ggttacttca cgaagttcgt
     9481 ctttcaatga acacaataat tcatcattca atgaattttc cataaaactt tctatttaat
     9541 tgattataaa aaagccattc cagaaagata agcaatcatt acttacttcc cggaatggtg
     9601 tctaatacct cgaaaacaaa gacttatatt ctaacctaat gtactcactt taatccattt
     9661 cttttgattt tgcattccat accagcaaag caaacaacac cgaaagcaaa gcagcaccaa
     9721 tccaaaacca attgatatag gtgaagtcat aaacatctac tccattctga acagtctttt
     9781 gcccttctat cagtataccg ctcatcacgt cctgcaatcc ggcaccgata taactggcaa
     9841 taccaactac tcccaatgca gcacccgacg cattacgggg agcaatatcc actgccatca
     9901 aaccacccag aaaacagatc aaaactccga tacctaaacc gaaaagaacc attgccaaca
     9961 cgtctatccc aaaatgagct cccggaacta agagaaacaa acaaagagca aacacattca
    10021 tcaacccgaa aattaacgca ggaacattgc gacgtccacc aaataactta tcggaaataa
    10081 cacctgaaaa catagtaccg attatgccac agaccggaca aatagaaatg ataaaactgg
    10141 catccaaggt ggagtaaccc ttttgagctt ccaaataaaa aacgccccaa ctattgatag
    10201 cataacgact gatatacata aaagcactcg aaagagccag tatccaaatg gcaggcatca
    10261 gcaatacctg acgctgtgct ttattaaaat cagccgtttc tgtctcactc atttcctttt
    10321 tctgtttggg aacattcacc gaaggaaatc ccatgctttc gggagtatca tggaagaact
    10381 tccagacgat caacgctcct atcaatccca ctataccggc tccgaagaaa ccataccgcc
    10441 agcccaacac actgacaatt gaggctatta tcagaaaagt caacgcttcg ccgatattat
    10501 ggctcgcaga ccaaaagcca tagtatgaac cgcgctcttt gtccgtgaac caacgggaaa
    10561 gccctactac acaagaggct gctcccatag attgaaacca gccgctaatc ccccaaagga
    10621 tagcgaacag gataaaagaa ttagtaaaac cgagacagag gttaaccaaa gcggttacca
    10681 ataaaccggt agtcataaaa cggttgatat tactacggtc ggcaaggaaa ccgttcgtga
    10741 atttcccgat ggcataggtg aaaaacaata cggaacctat gatgcctaac tctgtttccg
    10801 aaaaaatgcc ttcatctaca ataggtttct ttacgacatt cagactaaga cggcacacat
    10861 aatacatacc gtaaccaaaa gtcgcagaaa ggaaggtaga ccatttcaga aacttcaaac
    10921 ggcgggcatc ggatgaagac aaagtttctc cgttacaagg tctcggtgaa gagaccttgt
    10981 aaaaattgat tagttgtttc aacatgaagg aagtgcgttt aatcgtgaag tttcttgtta
    11041 cgcaaatact ccaataataa agcaggacga tctgtttgaa ttagcttggc tccctgggca
    11101 attatccacc cccaactttc atccggctga tgaagttcta ctgcacggtc gtcatcatgg
    11161 ccgccacaga gtttaggcca caaagaatta acaaaaagcc ttgcgccact atcacgcact
    11221 ttctgaatca atcgaagagt ctctttttca tcattatcaa agactaattc ataagctatc
    11281 ggtttcaaat gtttctgata actatctatt attttttcag catcttcctt atttaaattt
    11341 atcactggca taaaaatcac tttatccaat acttccccgt tctccacttt tacttgttca
    11401 tagggaagtc cagctttgat aacacattgg tcaactgttc ccgttttttc cagaatacaa
    11461 taagcctctt taaaataatc atacccctta tcaatattga ctaatatttt gcccttacat
    11521 aataacatga cttcttctaa agtaggaata agatgagtag tcttgtgagc tgctccattt
    11581 tttagacgaa aacgccgcaa ttcttccaaa gtgtaatttt ccggtttccc ttttcctgtt
    11641 gttgtgcgat caattgtttg atcatgcatc acaatgagat gtccgtcttt cgttttcttc
    11701 aagtcaactt cgaccatatc aactcccata tcaatacaat tttgtattgc ttgcaaagaa
    11761 ttttccggtg catttctcca atcaccacga tgagaaacca ccatcaccga atgattattt
    11821 ttatctaaca aattcgcacg taactttcta ttctgagcat ttatccccga aatagcaatg
    11881 agcaacaaac taaaaatgaa taactttctc atattgtttc agtattttta tctattgatt
    11941 ctgattttta aacaagctct atcgtcaaag gagcagtttc ccttcttaat acctttagta
    12001 cttttatatt ggcgcataca aagaggatca ttctccaaga tattcatcaa ataacattct
    12061 gattccctca aagtcggaaa caaacaagga tagccgtcag acgacaagac tatttgtgta
    12121 tgatttccta tggagaaaat acgtacctga tgcatattaa tgggaaaacc atcaaaaacc
    12181 ggaaaagaat atggttgatt tttatcagga ttgttttgaa gtatagcttg ctgctggaga
    12241 aaacgataaa taaaattacg ccctggatca ttgctcaata aatcatccgg tgtagcacca
    12301 tttaacaaag ctatttcatt tactaccgca cgcgcattag ccattatagc gtcaatttcc
    12361 ttttcatttg aagagtaagt attaccaaaa agacactgac agtccccgat ttgccatatt
    12421 tcattctttt cataactata aatcactcca ttggcagtaa aacggctacc gggtgttttc
    12481 tccaactctt ccaacaaacg atgctgaaca taaaaagaat gtattttctc tgttatcctt
    12541 ttcagagctt cattggcatc aatatcttta gggaaatcgt gtatcgcctc aatgaccagt
    12601 tccatcgcta tacgccccgt tttttttcca tcaatctcca attccgattt tgccgtagct
    12661 ccatcaatga ctgctgcaaa atagggagtt acaattatcc catcttcatt tgtagcagga
    12721 gtatgcttac ctttcaagaa tacttcttct acatcaaaat taggacttgt ttgcattgtc
    12781 cattcattct ctacggaaag gtaatcccaa ttttcaatac attcccattt ctttttcaat
    12841 tctttctttt tcaaataatt tattaaatat gcaggtctgt ctgtttgcaa tatagaagcc
    12901 ccgagcgaat ctatcaaata gccataacct tcatccggat caactaaaga gcaatcatca
    12961 tcgtgaccgc ctgcatgggt attccacaaa gtattatacc aaattcgtgc tcgccctttc
    13021 atcgcatttt ttacatcata gggtaatctg ttcaaatcag atgcaaattt gaactctacc
    13081 gccacaggat ttattatttg taaatagtca tccaaacgct gcattgcatt tttatcgtcc
    13141 aaattaatct ttggcataaa gacgaccttt tttagatatt tcccatagtt ctttttcaca
    13201 taatctgccg gagcatcgct tttcattatt accatatcgg tcgttcctgt cttctccaat
    13261 agggtataaa cctgatcaaa ataatcaaaa gctttgtcca aattaagcat cactctacct
    13321 ttagcaaaca gtaatgcctc ttctaaggtc ggtactttat aaatagtttt tatatgacaa
    13381 ccatttcgca attgaagtgc tttaatttct gccagcgtat gatctgcaac cagtcctttg
    13441 ccggtcgttg tccggtccaa cttagaatca tgcattaata tcaagtgtcc atctttcgtt
    13501 cttgccaaat caacttctac aatgtctacc cccattttta ctgcattatc tattgcctct
    13561 atagaattct cgcaagcatt tcgccaatca cctctatgag aagctactaa tacattcttg
    13621 ttttcaggag caaacagttt attgcgaata ctgtctaatc tggtctgagc aaatg
//
