LOCUS       c00022_gnlPro..        13832 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EJLKHBLK_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:41:45
            Original ID  :: gnl|Prokka|EJLKHBLK_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13832
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13832
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[318:3832]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      319..3832
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13832
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13832
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(319..1074)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_1"
                     /sec_met_domain="Fer4_7 (E-value: 2.1e-11, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.5e-24, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.4e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(1111..3090)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.3; E-value:
                     4.6e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.2e-61, bitscore:
                     202.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.4e-36,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             complement(3128..3832)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="SucD_FumR (E-value: 1.7e-130, bitscore:
                     426.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSSPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             complement(4044..4913)
                     /locus_tag="ctg22_4"
                     /transl_table=11
                     /translation="MPGDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLRERQIVLQAIGSKVEILALTDVEYVVYWFNELPLLCEDR
                     YKEMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLGSFFYPISTYTESFHYFVMQNYSNVKNVEEFAHLGGYTTTTFRRLFKNLYGVPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
     CDS             5187..6149
                     /locus_tag="ctg22_5"
                     /transl_table=11
                     /translation="MLMLRKIVFFLFVFVGLSLFAQQDYMVSSYVRGNFYNRGRISTES
                     LRASDDLIFLNVHPNKDGSLSFENPRVFQGKGMTTWAGLIKSVRAKVKGTKVKIRLGAS
                     SGEWKAMVADEAARTTFAKNIKTVLEKNKLDGIDLDFEWAENEKEYKDYSLAILKMREV
                     LGNKYLFSVSLHPVCYQISKEAIEAVDFISLQCYGPSPVRFPIEKYCSDIQMVLEYGIP
                     KEKLVAGVPFYGVTKDNSKKTEAYFSFVQEGLITEPAQNEVIYKGEKYVFDGQDNIRTK
                     TRYAMEQGLKGMMSWDLATDLPLDDSKSLLKAMVEELRK"
     CDS             complement(6267..10385)
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="MKKHIASILFLFLLSTFQLIAQSHSVKRLGIEQGLSNNYVVSITQ
                     DKQGFLWFATEEGLNKFDGTRFTTYYKNDLAQNNQGITGNELNRVYADTKRPIIWIATQ
                     RDGLNAYNYNEQTFTAYQHNPENPHSLITNDVTDISPSTQHDDGLWISTYYRGIEYLDI
                     TSGQFTHYNKSTVPGLPCDQTWTVLDGGDGNLYIGHVGSGFSIFSPKDKSVKNFRNEAG
                     NPMSLPGNDVFCIIKDANGNIWLGTNNGLALYDAANENFIMFKNNKNDKYATLCSRILS
                     IRQLKDNRLWIASELNGIAILNLKQSMFLSPEEISLEYIQEGADSRSLSNASARCIFQD
                     SFDNIWIGTWGGGINFISSKPPLFTTLSYSPIPNNENSLNNKVASSLCMDRQGRVWIGT
                     DGGGINVFEGEKRIAIYKKESGNIPSNFILASLQDSKGNLWFGSYQGGISYYDNRNKKF
                     RSISLMGQSNLDVRTIYEDTQHNIWVGYSGGIVILNPLTMEIIRHYNTENSELQSDFIR
                     SITQDEKGRFWIGTFGDGLGIYTPDLQKIKTFTQRDGFCSNTVNQIIQDKQKRMWIGTG
                     EGLVCFLSTDELNYKTYQRKDGLINTNICAIAEDKKGNIWFSNNKGISCYVTSKDCFYN
                     YSHSDDVPAGSFSSSCVTQNKNGWIYFGSINGVCCFNPDITMNEQPAPAAVITEMKILG
                     RLSNLENNDMIINLSKGQNVELSHAQNSFGLTFNVQNYSLVNQVEYVYMLKGLENSWYT
                     VNENNSVTFRNIPPGKYEFLIKARVHNQEWPEEATSLTIRVNPPLWLTWWAKLIYILVS
                     ISIIYLILHAYKKKLDLESLYILEKKNHEQEQELNQERLRFYTNITHELRTPLTLILGP
                     LEDMQKETSLPVKQAQKLSVIHQSALRLLNLINQILEFRKTETQNKKLCVSKGNIAPLI
                     YEIGLKYKELNQKTKIDFQIQIEKEEMLLFFDKEIITIVLDNLISNAIKYTEQGRVTLS
                     LYQTMRNEVAYTEIKVSDTGYGISAEALPHIFDRYYQESGKHQASGTGIGLALVKNLVT
                     LHEGEIRAESMQNEGSTFYISLLTDNIYPNALHVDSTEPIQEDTNQEASLEYPQETTLD
                     TGKPILLIVEDNEEIQKYIAESFADSFEVLTAYNGEEGKQQALSRIPDIVVSDIMMPVM
                     DGITLCRQLKEDVRTSHIPVILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINN
                     LLESRKKLIAQFQTQSVPGNQADLKEKRIVIAEALSKLDNEFIEKITLLIEENLSSEKI
                     DITYLSDKMCMSGSTLYRKMKALTGLSTNEYIRKVKMQNAERLLLEGKFNISEIAYKVG
                     MNSTGYFRQCFKEEFGVSPSDYLKQIIQS"
     CDS             10576..13707
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MRYLRILCICIIQLFLSAVAFAQTQVTGHVADVRGEDIIGANVTV
                     KGTSNGTITDIDGNFTINVDDKNGTLAVSFIGYKTKEVKIGEKARLQIVLEEDTETLDE
                     VVVVGYGTQTKKSLTGAISDVKSDALTRSVSTTTAGALSGKIAGVSTRAVDARPGRGIN
                     LEIRNMGSPLFVIDGIPYGGMNSRDWLQASDVSGSDVFNALNIEDIESITVLKDASAAI
                     YGLRASNGVVLVTTKKGKKNDKVSINVNGYYGWQNLTRFPKLANAGQYVRGLAEAAQNR
                     GEDPSKLYSPEELAKWEAGTEPGYKSYDYYDMVMRKNVPQYHINANVTGGSEKTNYYLS
                     VAHTGQDAMMRDFKYERTNLQLNIDTKITDRFTIGAQISGKYEKTEDVGLPGGDGYYSA
                     ILSMFKMQPIESPYANDNPEYINNVHENGYNPAAFSRDIAGYKDNLTRNANINAYAQYD
                     FSFGLTAKATFSYNYTNSRFDGYQYAYQIYTYDKEKETYNGTPAVGRWRSQIDRSVPAR
                     YMQLQLNYAKQIKNHNISAVLGYEASDYDWTKKTYGTEPSTDYLPLLQFDELNSFGDEW
                     SYEARAGWIGRINYDFAHKYLIELLARYDGSYLYAANNRWGFFPGVSIGWRISEEKFFE
                     KLRPVVDDLKIRASIGQTGTEKDVKLFDYLSGYTWNNGNAVLDGELVTGLNQRGLPITN
                     LSWTKNTTSNIGFDLTMFNNRLKITADAFRKDITGVPAARYDVLLPSEVGYSLPNENLN
                     KQAYIGAEGMVTWTDHIGDLNYTVSGNFTFSRYKSIETYKPRFNNSWDEYRNSAEGRWG
                     GIYWGYQVIGQFQSEEEIRNYPVNLDGNNNRTLLPGDFIYKDVNGDGIINGMDERPIGY
                     PEGWAPIMSFGGNIGLQWKGIDLNIDLSGGAMQGWRQNYELANAYHGNGNSPVYLLEDR
                     WHRADLYDPDSEWIPGRYPAIRKGEFSYNNKNSDFWLHNVRYLRIKNLEVGYSLPAQLL
                     RPIRAQKVRVYANVSNLCSFDNVGKFGVDPEITAAAAVVYPQQRTFLLGFNITY"
ORIGIN
        1 ggaaaaggct aatgactaaa aagggatcat tagccttttt attttaatac actatataga
       61 atcgcggaga cgcttacagc ggtaatgaat gattttacct tatttcaatc ctcgctttca
      121 cccgtaattc tctcattcat aacagttctg gctataaggt gaaatcggtg aaacttatga
      181 attaaaagtt catgttactg atccgtatta ataataattg tgatctactc atacataaag
      241 aaatcccctg tcggactagc cggcagggga ttctgtcatt aatcaaatta agctctcgct
      301 attgaaatct agcaatttct agtcttttaa ttttgcgatg atgaagtcgc ggttcaagcg
      361 agcgatgttg ctgatagaaa tatttttcgg acattcagct tcacaagcac gagtgtttgt
      421 acagttaccg aatcccagtt catccatctt tgacaacata gcttttgcac gacgcaaagc
      481 ttccggttta ccttgcggca gcaagttcaa ctggctgact tttgcagaaa cgaacaacat
      541 agcagaacca ttcttacatg cagctacaca agcaccgcaa ccgatacaag aagcagcatc
      601 catagcttcg tcagcgatag gtttcgcgat caggatagcg ttagcatcct gcggagcacc
      661 tgtgcgtacg cttacataac caccagcttg cataatcttg tcgtatgcag tacggtctac
      721 catcaagtct ttgatgacag ggaaaccagc cgaacgccaa ggttcaacag tgatggtatc
      781 accgtcgttg aaacgacgca tatagatctg gcaagtagta gcacctgttg caggaccgtg
      841 cgggtgtccg ttgatgtaaa gagaacacat accgcagata ccttcgcggc agtcatgatc
      901 gaatactacc ggttcttttc tttcgctgat gagctgttcg ttcagaatat ccagcatttc
      961 gaggaaggaa gtatcaccgg ggatatcttt catttggtag gtttcaaaag cacctttagc
     1021 tttcggacca gcttggcgcc ataccttcag tgtaaatgat atatttttat ccattttctt
     1081 ctaattcttt taaatgttta acttcaccga ttagctcttg tagttacgag tctgaacctt
     1141 gatagcttcg tataccagcg gttctttgtg caataccgga gccttttcat catcaccttg
     1201 atattcccag catgctacat agaagaagtt ttcgtcatca cgttttgctt ctccttcttc
     1261 agtctggtat tcttcacgga agtgaccacc acaactttcg ttacggttca atgcatcgta
     1321 agcaacaagc tcacccatag tgatgaagtc gtacagacgg attgctttgt caagctctac
     1381 gttcatacct tccttagaac cggggataaa caagttcgtt tcgaattcct tgcggatttc
     1441 tttcagttcg gcgatacctt tcttcaggcc ttctgccgta cgtcccatac ctacatattc
     1501 ccacatgaca tgacccagtt tcttgtggat agaatcaaca gattctttac cctggatgct
     1561 catgaacttg tcgatcttag cttgaactgc tttttcagct tcagcaaatt caggaagatc
     1621 ggtagagaaa cgaggaacag tgatctggtc tgccagatag ttttggatag tgtaaggcaa
     1681 tacgaagtaa ccgtcagcca aaccttgcat caatgcagaa gcaccgaggc ggtttgcacc
     1741 gtggtcggag aagttacatt caccgatagc gaacagaccc ttgatagtgg tttgcagttc
     1801 gtagtctacc cagataccac ccattgtata gtggatagcc ggataaatca tcatcgggtt
     1861 ataatatttc acaccactga tttctttagc cagttcgccc ggattaacgt cagtgatttc
     1921 ttcgtacata tcgaagaggt taccataacg ttgaagaaca acgtcgatac ccaaacggtt
     1981 gatagcttca gagaagtcga ggaatacggc caaacctgtg ttgtttacac cgaaaccagc
     2041 gtcgcaacgt tctttagcgg cacggctggc aacgtcacgc ggaaccaggt taccgaatgc
     2101 cggatagcgg cgttccaagt aatagtcgcg gtcttcttca ggaatatcac ttcctttgat
     2161 ttcgcctttc tgaagtttca cagcatcttc ttttttcttc ggaacccaga tacgaccgtc
     2221 gttacggaga gattcagaca tcaaagtcag cttagactgc ttgtcgccat gtaccggaat
     2281 acaagtcggg tgaatctgaa cgtaagcagg gttagcgaat acagcaccct tgcggtagca
     2341 agagatagca gctgtacagt tacaacccat agcgttagta gacaggaagt aagcgttacc
     2401 atagccacca gtagcgatta ctacagcgtg agcagcgaaa cgttccaatt cgcctgttac
     2461 aagatttttt gcgatgatac cgcgggcacg tccgtcaacg atgacaacat cctgcatttc
     2521 atagcgggta tacagtttaa cagtacctac gtttacctga cggctcaatg cagagtaagc
     2581 acccagcagc aactgctgac cagtctggcc tttagcgtag aaagtacggg atacctgtgc
     2641 gccaccgaaa gaacggttgt ccagtgtacc accgtattcg cgagcgaaag gaacaccttg
     2701 tgctacacat tggtcgatga tagcgttaga cacttcagcc aaacgatata cgtttgcttc
     2761 acgggcacga tagtcgccac cttttacagt atcgtagaac agacggtaaa ccgagtcacc
     2821 atcattttga tagttctttg cagcgttgat accaccctgt gcagcgatag agtgtgcacg
     2881 acggggagaa tcctgaatac agaaattgaa tactctgaaa cccatttcac caagtgaagc
     2941 agcggcagaa gcacctgcca gacccgtacc cacaacgatg atgtccaaac gacgtttatt
     3001 agcggggttc accaatttct ggtgagcttt atagttggtc catttctcag ccaccgggcc
     3061 ttctggaatt tttgaatcta tcttgatcat aatattattt acaatttaat catttacaat
     3121 ttactattta gcaagcaccg ccacaaatca gtgttttcac gaagaatacc actactacca
     3181 gtgcgaaacc gagtacaaca atcgtagaat agatgttaga aatgcatttc caacgattga
     3241 tccatacttt gttgttccat cccagtgatt gcatagagct ccagaaaccg tgagtcaggt
     3301 ggaaccacaa agcaaacagc caaacgaggt aaagaactac gtaaaccggg ctagagaaag
     3361 tctgctggat gtgataagca ccgttagcgg cataagccag cgtcagtgta tcagcgtgca
     3421 tgcccatgtt gtgcatcagt tccggcaact gcatttttgc ccagaagttg aagaggtgca
     3481 aaccaagacc tacgataacg atcagaccca gcaccaacat gttttgagat gcccattcta
     3541 cagtttttgg tttgtcaacc actgcatagc gttcgctacc acgcgctttg cgattctgca
     3601 ttgtcagcca gaatgcgtag atgatgtgaa tcacaaaaag agcggctagt cctgcggtag
     3661 ccactaacgc ataccagttt gctcccagga actcacaaat catgttgtaa ccatcagccg
     3721 agatgattgc aaccaagttc atcgccatgt gaaatgttag aaacaggaca agggcgatac
     3781 cggtaacgct catcaccact ttccttccta cagatgaatt acttaaccac ataaatgatt
     3841 gaatttaaat tatttaattg ttagaactaa aatttcgacg ttttacacct cttacagact
     3901 gcaaaaatag gggaaataga ttgattgagc aaggaattaa agaaataatt ctttaataat
     3961 gaatcaatgc gctaatgtat caatatgcca gccagtatgt acgcatggtg caactgattg
     4021 gcacattcgt aggatgaggc tgtttattgt actttcccga ttttctcacc gccggctgct
     4081 ttcttgcgta aagcgcgtgg ggtatctccg aaagagtctt tacaaaagtg ggcgaaatgc
     4141 gacagggagt cgaatccgta tctgttacaa atttcagtga ttcgcatttt ggtgtgctgt
     4201 aggtcttcca ggattccttc ccgtttcttt tccagtatcc attcgtatac gggcacacca
     4261 tagaggtttt tgaaaagtcg gcggaaagta gtggtcgtat atcctcccag atgcgcaaat
     4321 tcttccacgt tcttcacgtt gctgtaattc tgcatgacga aatagtggaa actttccgta
     4381 taagtgctga tcggatagaa gaatgaaccc agttggggca gcggatagaa gttggtaatc
     4441 aagaaaacca gttctttgca ttttaagtcg atatacttgc tgcaagggtt ttcttcagcg
     4501 aggaattcgg gcatactggt gacaaggtgg taaagccttt cactcataat cagtggagtg
     4561 taggtcaaag gagcttccgc ctgttccatc atttccttat atcggtcttc gcagagcaaa
     4621 ggtagttcgt tgaaccagta gacaacgtat tcaacatctg tcagtgccag tatttcgacc
     4681 ttggagccaa tagcctgcaa aacaatttgt ctctcgcgta acgttattcc gggatgctct
     4741 tcgctattga taagtaattc gccctttatc ataaaaagca tacaattctg tgtacactta
     4801 tccttgggga tatgctctcc tttaggtaag tttctatata caaggatatt ctcaacattt
     4861 tttggacatc ccgtacagtt ggtatattgt atgcaaaatg aatctcctgg catgagtttt
     4921 atgcgtgatt tattatctta acggaacaaa gatagacttt ttttgcggaa aatggaattc
     4981 tttcttttat ttatgtttta gtagaaacct gcaaatatta ttcttatccc tttggatgat
     5041 gttagagaat tcaatattta tctgttttaa atttctgaat agaaaacttt atgttgattt
     5101 ttggaagtat tatagttgtt tttgaacatc tgtttgcttt tgatatgcgt atttttgcga
     5161 tctaaacgtt ttaattatca atcattatgc taatgctaag aaaaattgta ttcttccttt
     5221 ttgtgtttgt tggattatca ttgtttgcac aacaagacta tatggtcagt tcttatgtgc
     5281 ggggtaattt ttacaaccgt ggtcgtattt ctacagaaag cttgcgggca agtgacgacc
     5341 ttattttctt gaatgttcat cctaataaag acggatcatt gtcattcgag aatccgcgtg
     5401 tatttcaggg aaaagggatg accacttggg caggtttgat taaatcggtt cgtgcaaaag
     5461 taaaaggtac aaaagtgaaa atacgtttgg gagcttccag tggcgaatgg aaagcgatgg
     5521 tggccgatga ggccgctcgt acgacgtttg caaagaacat aaagactgta ctggaaaaga
     5581 ataaactgga tggcattgat cttgattttg agtgggcaga aaatgagaaa gaatataaag
     5641 attatagttt ggctattctg aagatgcggg aagtgttggg aaacaagtat cttttcagtg
     5701 tatctctgca tcctgtttgt tatcagatta gtaaggaagc tattgaagct gttgatttta
     5761 tttcacttca gtgctatggt ccttcaccgg ttcgctttcc gatagagaaa tattgttcgg
     5821 atatacagat ggtattggag tatggcattc cgaaggaaaa actggtagca ggagttcctt
     5881 tctatggtgt gacaaaggat aattcgaaga agacagaggc ttatttcagt tttgtacaag
     5941 agggactgat tacggaacct gcacaaaatg aagtaatata taagggagag aaatatgtgt
     6001 ttgacggaca ggacaatatc cgcactaaga cccgttatgc gatggagcaa ggactgaaag
     6061 gcatgatgag ttgggattta gccacagatt tgccgctgga tgattctaaa tcattgctca
     6121 aagcgatggt tgaggaatta agaaaatgac ctcccctaca ggtcgcagag tttcctattg
     6181 ggaggtatca gaagggattt ttcattattg ttctgaatga tagagcaaca tgaaagtaaa
     6241 ttctacttct gatacatctt cctttctcaa gattgtataa tctgcttcag gtaatccgaa
     6301 ggcgagacgc caaattcctc tttaaagcat tgacggaaat accccgtact gttcattcct
     6361 actttatagg cgatttcaga gatgttgaac ttcccttcaa gcaataaacg ttctgcattc
     6421 tgcattttca ctttccggat atattcgttg gtcgataatc ctgtcagtgc tttcattttc
     6481 cggtagaggg tggaaccgct catacacatc ttgtctgaaa gataggtaat atcaattttc
     6541 tccgaagaga ggttttcttc gattaaaagg gtgatttttt caataaattc attatccagc
     6601 ttgcttagag cttcggcgat tacgatacgt ttttctttta aatctgcctg attgcccgga
     6661 acggattgtg tctggaattg agctatcagt ttctttcttg attccagcag attattgata
     6721 cggctacgca gcagagaagc actgaaaggc tttgtcagat aagaatcggc tcctacctca
     6781 tatccttctt ctttatcttg cagagaatcc ttggctgtca ataaaatgac agggatatga
     6841 ctggttcgta cgtcttcttt caattgccgg cagagagtga taccgtccat gacaggcatc
     6901 ataatatcgc tgactacaat atccgggatg cggctaagag cttgttgctt cccttcttct
     6961 ccgttgtagg cggtgagtac ttcgaacgaa tctgcgaagg actcggcgat atatttctgt
     7021 atctcttcat tgtcttctac aatcaacagg atcggtttac cggtatccag tgtggtttct
     7081 tgtggatatt caaggcttgc ttcctgattc gtatcttctt gaatcggttc tgtagaatct
     7141 acgtgtaaag cattgggata gatattatcc gtcaataggc tgatatagaa agtacttcct
     7201 tcgttttgca tactttctgc ccggatttct ccttcatgca gggtgaccag attcttcact
     7261 agggccaagc caatgcctgt tccggatgcc tgatgcttgc cgctttcctg ataataacgg
     7321 tcaaaaatat gtggcagggc ttcagcagaa attccatatc ccgtgtcact gacttttatc
     7381 tctgtataag ctacttcatt acgcattgtt tgatacaaac ttagagtgac gcgtccctgt
     7441 tccgtatatt tgatcgcatt ggaaatcagg ttgtccaaaa cgatggtaat gatttcctta
     7501 tcaaagaaaa ggagcatttc ttctttctct atttgaatct ggaaatcaat cttggtcttt
     7561 tgatttagtt ctttgtattt aagccctatc tcatagatca gaggagcgat attgcctttg
     7621 ctgacacaca atttcttgtt ttgtgtctct gtcttccgga attccagtat ttgattaatc
     7681 aagttgagca gccgtagtgc actctgatgg atgacagata acttttgggc ttgttttacc
     7741 ggaagtgagg tctctttttg catatcttcc agaggaccga ggattaaggt caacggtgta
     7801 cgcagctcat gggtgatatt ggtatagaat cgcagacgtt cctggttcaa ttcctgttcc
     7861 tgctcatggt ttttcttttc caaaatatag aggctttcta aatccagctt ctttttatat
     7921 gcatgcaaga taagataaat gatgctgata gatactaaaa tatagataag ctttgcccac
     7981 cacgtcagcc aaagaggggg attgacacgg atggtaagtg aagtagcttc ttcaggccat
     8041 tcttgattat gtacccttgc tttgatgagg aattcatatt ttcccggagg aatgtttcgg
     8101 aaagtgacgc tgttgttctc attgacggtg taccatgagt tttcaagccc tttcagcata
     8161 taaacatatt ccacttggtt gactagtgag tagttttgta cgttaaatgt aagtccaaag
     8221 ctattttgcg catgacttaa ttctacattc tgtcctttgg ataaattgat aatcatgtca
     8281 ttgttttcca gattgcttaa ccgtccgagt attttcattt ctgtgataac tgctgccgga
     8341 gctggttgtt cgttcatggt gatatcggga ttgaaacagc atactccatt gatagaaccg
     8401 aaataaatcc atccgttctt gttttgtgta acacaactgc ttgagaaact tcctgccggt
     8461 acatcatcag agtgactata attgtaaaaa cagtctttgc ttgtaacata acagctgata
     8521 cctttgttgt tactaaacca gatatttcct tttttgtctt ctgctatagc gcagatattt
     8581 gtattgatca ggccgtcttt ccgttgataa gtcttataat tcagttcatc ggtagacagg
     8641 aaacaaacca atccctctcc tgttcctatc cacattcttt tttgtttatc ttgtatgatc
     8701 tggttgacag tattggaaca gaaaccatcc ctttgagtga acgttttgat tttttgtaag
     8761 tccggggtgt atataccaag tccgtctccg aaagtcccaa tccagaaacg ccctttctca
     8821 tcttgagtta tggagcgtat aaagtcactt tgtagttcgc tgttttctgt attgtaatgt
     8881 cggataatct ccattgtaag agggttcaat ataacaatcc ctccactgta tcctacccaa
     8941 atgttgtgct gggtatcttc atagatcgta cggacatcca gattagattg ccccataaga
     9001 gagatggaac ggaatttttt attccggtta tcataatagc tgattccccc ttggtaggaa
     9061 ccaaaccata aattaccttt tgaatcctgc aaagaggcta atataaaatt cgaaggaata
     9121 tttccactct cttttttata gatagcgata cgtttctctc cttcaaatac attgattcct
     9181 ccaccgtctg ttccgatcca aacccgtcct tgtctgtcca tacagaggct actggctact
     9241 ttgttgttca aactgttctc attgtttgga ataggggaat agctcaatgt ggtgaacaaa
     9301 ggtggtttac tgctgataaa gttgattcct cctccccatg tccctatcca gatattatca
     9361 aaagaatcct ggaatatgca tcgggcactt gcattagaaa gacttcggct atcagcaccc
     9421 tcctgtatat attcaagaga aatctcctct ggcgaaagga acatactttg tttaaggttt
     9481 aatatggcaa tgccattgag ttctgaagca atccaaagcc tattatcttt cagttggcgg
     9541 atggataata tacggctgca taaagtagca tacttgtcat tcttgttgtt tttgaacatt
     9601 atgaagtttt cattagcagc atcatataga gccaatccgt tatttgtacc taaccagata
     9661 tttccatttg catcttttat aatacaaaac acatcattac cgggcaaact cattgggttt
     9721 ccggcttcgt tccggaagtt ttttacgctc ttgtcttttg gagaaaaaat actgaacccg
     9781 cttccgacat gcccgatata caaatttcca tcacctccgt ccaatactgt ccatgtctgg
     9841 tcgcaaggta gaccgggaac tgtactttta ttataatgag tgaattgtcc gctggtgata
     9901 tcaaggtatt ctatacctct ataataggta ctaatccata aaccatcatc atgttgagtg
     9961 gaaggagaaa tgtctgttac gtcattcgta atcagactat gtggattttc cgggttatgt
    10021 tgataagcgg taaatgtttg ctcattataa ttgtatgcat ttagtccgtc tcgttgagtg
    10081 gctatccaaa taataggacg tttggtgtct gcatacaccc ggttaagctc gttgccggta
    10141 attccctgat tattctgtgc caaatcattt ttatagtaag tagtaaagcg ggtaccgtca
    10201 aacttattaa gtccttcttc tgtggcaaac cataagaatc cttgtttatc ttgtgtaatg
    10261 ctgactacat aattatttga taatccttgc tctatcccca atctttttac agaatgagac
    10321 tgggctatca actgaaaagt tgataacaag aataaaaata gaatagaagc aatgtgtttt
    10381 ttcataactt gtgcttattt gtttcaatta caagtccaaa aataggaata aatattttat
    10441 ttagagtatg taaatcgttc attgcatgat ttgtgtagct cttatgcatg atttttgttt
    10501 attcagtcta tattaatgac gtatatttgt gttcgaaaaa acaacaaaaa atgtttaatc
    10561 tttaaattct aatttatgag gtatttaaga atcttatgca tatgtatcat acagctgttt
    10621 ctgtctgctg ttgcatttgc acaaacacaa gttacaggac atgtagctga tgtaagggga
    10681 gaggatatca ttggtgccaa tgtaactgta aagggaactt ctaatgggac aattacagac
    10741 atcgatggta attttacaat caatgtagat gataagaatg gaacactggc agtctcattt
    10801 attggttata agactaaaga agtgaagatt ggcgaaaagg cacgtcttca gattgttctt
    10861 gaagaagata ccgaaacttt ggatgaagtt gtagtggtag gttatggtac acaaaccaag
    10921 aaaagtttga ccggagcaat cagtgatgtc aagtctgatg cgttgacacg ttctgtttct
    10981 accaccactg ccggagcgtt gtccggtaaa atagcaggtg tatctacacg tgctgtggat
    11041 gctcgtccgg gtaggggaat taatctcgaa attcgtaata tgggtagtcc gctgtttgta
    11101 attgatggta ttccttatgg aggtatgaat agtcgtgact ggttgcaggc atcggatgtt
    11161 tccggtagtg atgtctttaa tgctctaaac attgaagata ttgaaagtat cacagtcttg
    11221 aaggatgctt ctgctgctat ttacggtttg cgtgcatcaa atggtgtggt tttggtaacc
    11281 accaagaaag gtaaaaagaa tgataaggta agtatcaatg taaatggata ttatggctgg
    11341 caaaacctga cccgtttccc gaaactggca aatgcaggac aatatgtaag agggttggct
    11401 gaagcagcgc agaatagagg tgaagatcca agcaagctat atagccccga agaactggcg
    11461 aaatgggaag ccggtacgga accgggatat aagagttatg actattatga tatggtgatg
    11521 agaaaaaatg tgccacagta ccacattaac gctaacgtga cgggtggttc tgaaaagacc
    11581 aattactacc tttctgtagc tcataccgga caggatgcca tgatgcgcga cttcaaatac
    11641 gaacgtacca accttcagtt gaatattgat acaaagatta cagatcgttt tacgatcggt
    11701 gcacagatca gcggtaaata cgaaaagacc gaagatgtag gtttgcctgg cggtgatgga
    11761 tattattcgg ctattttgtc tatgttcaaa atgcaaccga ttgaaagtcc ttatgctaat
    11821 gataatccgg agtatatcaa taatgtacat gagaatggtt acaatccggc agctttcagc
    11881 cgtgatattg ccggctataa agataatctg actcgtaatg ccaatatcaa tgcttatgcg
    11941 cagtatgatt tctcatttgg tttgactgca aaggctactt tctcgtacaa ttatactaac
    12001 agtcgttttg acggttatca atatgcttat cagatttata cctacgataa ggagaaagag
    12061 acttataatg ggactcctgc cgtaggacgt tggagaagtc aaattgatcg tagcgttcct
    12121 gcgcgttata tgcagttaca attgaattat gccaaacaga ttaagaacca caatatttcg
    12181 gctgttttgg gttatgaagc ctccgattac gattggacta agaagactta tggaacagaa
    12241 ccttctaccg actatttgcc gctattgcag ttcgatgagc ttaacagttt cggtgatgaa
    12301 tggagctacg aggcacgtgc cggatggatt ggtcgtatca attacgattt tgctcacaaa
    12361 tatctgattg aattattggc tcgctatgat ggctcttatc tttatgcagc gaataatcgt
    12421 tggggattct tcccgggtgt atctatcggt tggagaatct cggaagagaa attctttgaa
    12481 aagttgagac cagttgtaga tgatttaaag attcgtgctt ctatcggtca gacaggtaca
    12541 gaaaaagatg taaagttgtt cgattacttg agtggttata cttggaataa tggtaatgct
    12601 gtattggatg gcgagctggt taccggattg aaccaaagag gattgcctat tacaaatcta
    12661 tcctggacta agaacacgac atcgaatatc ggttttgacc tgaccatgtt caataatcgt
    12721 ttgaagatca cagccgatgc tttccgtaag gatattaccg gtgtgccggc tgcccgctat
    12781 gatgtattgc ttccgagcga agtaggctat tcgctaccta acgaaaactt gaacaaacaa
    12841 gcttatattg gtgcggaggg tatggttaca tggaccgacc atatcggtga tttgaattat
    12901 accgtaagcg gtaattttac tttctcacgt tacaaaagta ttgagactta caaaccacgt
    12961 tttaataact cctgggatga atatcgcaat tctgcagaag gtcgttgggg aggtatttat
    13021 tggggatatc aggtaatcgg ccagttccag tcggaagaag aaattcgtaa ttatccggta
    13081 aacctggatg gaaataataa ccgcaccctg cttcctggtg actttatcta taaagatgtg
    13141 aatggtgatg gcatcatcaa tggtatggat gagcgtccta tcggttatcc tgaaggctgg
    13201 gcacctatca tgtcatttgg tggtaatatc ggtttgcagt ggaagggcat tgacttgaat
    13261 atcgaccttt ccggtggtgc tatgcaagga tggagacaga actatgagtt ggccaatgca
    13321 tatcatggca acggaaactc tccggtttat ttgttggaag accgttggca tcgtgccgac
    13381 ttgtatgatc cggatagtga atggataccg ggacgttatc cggccatccg taaaggtgaa
    13441 ttcagctata acaataagaa tagtgacttt tggttgcaca atgtacgcta tctgcgtatc
    13501 aagaacttgg aagtgggtta cagcttgccg gctcaactgt tgagaccgat ccgtgcacag
    13561 aaggtacgtg tttatgcgaa tgtttctaac ttgtgttcgt tcgacaatgt gggtaagttt
    13621 ggagtcgatc ctgaaattac tgccgcagct gcagtggtat atccgcaaca acgtacattc
    13681 ctccttggat ttaatattac atactaaaaa cgaaagtgat catgaaaagc aaatctataa
    13741 aaatacttct gatgggagct gccatcacct ccatgttgtc gagttgtggt gacagttggt
    13801 tcgaaagaga acccaaaaac attcttacta at
//
