LOCUS       c00066_gnlPro..        24638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LANCIOCH_66.
ACCESSION   c00066_gnlPro..
VERSION     c00066_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:37:50
            Original ID  :: gnl|Prokka|LANCIOCH_66
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 88543
            Orig. end    :: 113181
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24638
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[98543:103181]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14638
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24638
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24638
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(1044..3776)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_70"
                     /sec_met_domain="Peripla_BP_1 (E-value: 5e-07, bitscore:
                     22.9, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPALTYYALLVLLLASCFSCKTDSEKKKFVIGVSQCTLEGSWRK
                     SMLLDMKVQASEYPGVSLLVEDAADSSLLQVEQIRSLIKRKVDLLIISANESEPVTPIA
                     IEAYRAGIPTILVDRKISSDEYTTYIGGNNYEIGRQAGFFVNRQVKEKYPTVLEVWGLS
                     GSSPAQDRHRGFMEVLNSRIKVKEIFGKWKPETVEKEIAEMDSLEEVDVVFAHNDVMAM
                     AARRAIERMHPGLADRISFVGIDAVSGRGSGLEAVMHGELAASVLYPTGGSLAIRVAMQ
                     ILNGEDVSRQYLLSSALIDKNNAGTLFIQSEQVVDYQHQIELQRENLESMLSKYTFLQN
                     SVGIILLLMGMLLLSALYVVHVNRAVKRKNRELKRTNLQVQQQKEELAEANRYIEKSTA
                     QKLQFFTNITHEIKTPLTLILGPLGKLSKEAPEGSSLADDIRIIRKNAERLKRVVDQLL
                     DFRKVESNKMNMRVGEVDLVAFVAEVKSYFDTMAATKQIHFTFEHDCPSVNIWVDRDKM
                     EKILANLLSNAFKFTLDGGTVTIHLKDKGDQVELSVEDNGKGIPSENIASVFDRFFTGD
                     QNYVTGTGIGLHLTREFVHMHKGTIRVESVPHKSTVFTVILLKGKSHFDESCTFDLSVT
                     ELSSGVADLNTDELQEVLNRTYNYTVLVVEDDLDIQSYLQAELKQNFRVLVADNGVKAL
                     EVLMNEDISMVISDVMMPEMNGFDLCRKIKSDIVLSHLPVMLLTALSDDKQQMYGAASG
                     ADAYIQKPFNIEVVKLRIIKLLEDRVRLREAYARDASSPAVSVKEEKAGSMDDLFMNRF
                     LKLIEESYADPDFSIEKGSEKLGLSRVHLYRKVKELAGVTPTDFLRNYRLKKAAALLRR
                     KAGNVNEVAYATGFGSPAYFSKCFKAVYNITPTEYLEKE"
     CDS             3873..4340
                     /locus_tag="ctg66_71"
                     /transl_table=11
                     /translation="MKIINEALLNETTGRAKQSPRLRMNYNFHEHLDDPVNRLLNALEP
                     GTYLRPHRHLNPKKDEIFLLLRGRIAVFLFDNKGEITQTQILDPKEGVYGAEIKAGTWH
                     GLLVLESGSIIYEIKEGPFAPLAPENFAPWSPAPEDTKGVAKYMELLGKAI"
     CDS             complement(4558..6387)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_72"
                     /sec_met_domain="Peptidase_U32 (E-value: 9.1e-73, bitscore:
                     237.7, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTKSRPIELLSPAKDLNCGIEAINHGADAVYIGAPKFGARAAAG
                     NSLEDIRELCEYAHLYGARIYVTLNTILKEDELEEAERMIWDLWRVGTDALIIQDMGIT
                     RLNLPPIPLHASTQTDNRTPEKVRFLEAAGFTQVVLARELSLNEIRRISEATTVPLEVF
                     VHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYTMVDATGTEIVTHKHLLSLKDM
                     NRSDQLEALLDAGVSSLKIEGRLKDVGYVKNITAYYRKKLDAVLSRRPEYRRASAGRST
                     YTFEPVAEKSFNRGFTPFLLEGRTADITAFNTPKSLGEPVGTVKEIKGNSFTVAGLKQL
                     SNGDGLVFFNRKGELEGFRVNRVEANRVFPLDMPQLTPKTPLYRNFDQAFDKLLAKPSA
                     ERKLSVEIEFLDNPFGFTLCMEDETGARIMLTEPFAKELARHEQQDNIRTQLSKLGNTP
                     FEASKVVVGLSENWFVPSSLLADMRRRGVEKLLEARRARYPRETVKRVQPSVSIPFPER
                     QLTYLGNVANGKARSFYQDHGVEQIDPAFELSPRKDVPLMFTKHCLRYSMGWCPTYQKD
                     KSPYKEPYYLLYKDTRLRLQFDCKHCQMLVFES"
     CDS             complement(6410..7342)
                     /locus_tag="ctg66_73"
                     /transl_table=11
                     /translation="MPLNLQKNLPAVELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMP
                     LKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMKEFYKDFDEMQDDFYDGMI
                     ITGAPVEQMPFEEVNYWEEVTEIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAK
                     MFGVFRHTLREPYVPIFRGFDDEFYVPHSRHTEIRREDVMKVPDLTLLSESEESGVYMA
                     MARGGREFFITGHSEYSPYTLNDEYMRDVNKGLPIAVPRNYYRNNNPALGPVVRWRGHA
                     NLLFTNWLNYYVYQETPFRIEDISKLGDL"
     CDS             7451..9856
                     /locus_tag="ctg66_74"
                     /transl_table=11
                     /translation="MKIRAIATLLFILFSISAFGQGRAKISGYIRDADGNPLDLVNIRV
                     KNTLNGTMSNEKGHYSLSVATGDSVTLIYSCLGYNKAERILPQVTKDMRLNVQMNYTSL
                     ELGEVVATAIRKQTTTLETLNADRVKLLPDPAGGSIESLVVTFAGVTSNNELSSQYSVR
                     GGSYDENIVYVNGLEVFRPLLIRSGQQEGLSFINPDMTEAVNFSAGGFEARYGDKMSSV
                     LDITYKKPKGFEGSASASLLGANAYVGSSSGKFTQVTGFRYKTGRSLLKTTDTDAEYDP
                     NFIDLQTYMTYQLAPKWEINFLGNLAINNYKFIPHTRETSFGTATNAKKFKVFMSGQER
                     DKFETLFGALTLKHNLNDNTELGLQASAFTSKEEEGYDIAGDYWLGDAAEEGGGEIQKL
                     SIARYNEHARNRLHSNIMNVGHYGVARIKNNTLKWGATVQLEKINDKISEWEKRDSAGY
                     SLPQGGGNVNVIANLFSDNKLESTRISGYLQDVFKFRTKQGLFTLVGGVRGSYWSYNRE
                     FIFSPRASIGFIPNFDQNLTFRLASGLYYQSPFYKELRTTVQDEHGNSIIQLNKNLKSQ
                     RSIHVIAGGDYTFRASGRNFKVSADMYYKKLDNLNPYTVDNVKIRYYGENCAQGHAMGL
                     DVKFFGEFVPGTDSWISFSLMKAEQSIRGSEYVPMPNSQGYNVSLFFQDYFPGYKRVKL
                     NLKGVLSGGLPVTAPRTGYEDGYFRTPTYKRVDLGFSYQLAGGTDAIMDRGFFRNLKNI
                     WLGLDIFNLFDIKNTSSYYWITNIDNHQYAIPNYLTGRQLNIRLIVDF"
     CDS             10001..10408
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_75"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2e-26, bitscore:
                     85.9, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEEVLGLKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALDEAESKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGK"
     CDS             10521..12074
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_76"
                     /sec_met_domain="CT_Btheta (E-value: 2.1e-291, bitscore:
                     960.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALRETARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIYAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLISFLPQNNLEETPLIECKDPIDRLDDNLNDIIPDNPN
                     QAYDMYEVIGTIIDNGEFLEVHADYAKNIIVGFARFNGQTVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12090..12983
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_77"
                     /sec_met_domain="OAD_gamma (E-value: 1.5e-11, bitscore:
                     38.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMINKKIGVLLLFALLVSFGAKAQRATSMRINEVLVINEDNFVD
                     DYGKRHAWIELFNNSAGSVNIAGCYLTNDKSNPKKYPIPKGDVLTVIPPRQHTLFWADG
                     EPDRGTFHVNFTLDPSKENYIALYDADGKTLIDEIVIPASQKADVSYGRTLDGQGEWTA
                     LTKVTPSTNNVTLDSNEKIENFKENDSWGIGMTLTAMAVVFSGLFLLFIIFKQIGKLSI
                     AASKRNAQKAAGAAVIADNAGQESGEIFAAIGAALYEMSDDNHDIEHTVLTIRKVQRSY
                     SPWSSKIYGLREVPKK"
     CDS             13006..13437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.5; E-value:
                     9.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_78"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.8e-20, bitscore:
                     65.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHISSVVDDIAEVEVNGTPYQVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVISRPAASTTKGAVKSPLPGVILQVNCKVGDTVKRGQNLLV
                     LEAMKMENNINADRDGKIIEIKVNKGDSVLEGADLVVIG"
     CDS             13442..14638
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_79"
                     /sec_met_domain="OAD_beta (E-value: 2.1e-152, bitscore:
                     500.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSVLLQAAGTAHESFLQFLGENLELFLTYTGVYNATPGHLIMI
                     LVGLLFIFLAIKYEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTS
                     GWYPPLIFLGIGAMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGI
                     IGGADGPTAIFLSSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTQKERLIRMKPP
                     RAVSSTEKIVFPIVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDT
                     ITILLGITVGASTQATQFLTLNSIKIFGLGALSFVIATCAGILFVKFFNLFLKEGNKIN
                     PLIGNSGVSAVPDSARISQNVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             14742..14996
                     /locus_tag="ctg66_80"
                     /transl_table=11
                     /translation="MRTTIHQKYINGCIIKNYLRHSLPFYIRPYQIFCSTVIGSVSGFA
                     SCSNVVPKNNQIINRIIAITTPKTSSTFVFFRLMSILQY"
     CDS             complement(15258..17348)
                     /locus_tag="ctg66_81"
                     /transl_table=11
                     /translation="MQITYYRHKKGVLRMHSRDMEYIVGLLKNGKDAEAILSVRRKLNM
                     AFLARTTDLSGKLPVLAFGSTFKKNGDGIQLRRYNGYVLLEVNGLESQSEAEAVRREAA
                     ALPQTLLAFVGLSGRSVKIVVPFVLPDGSLPKKEEQARMFHAAAYQLAVRHYQPQLGSI
                     ISLKEPFLSRGCRMSVDPDAYYNPDAVAIRIEQPLQMPDGGDLKIVPSPVRDPLEMMAP
                     GADRNGQIATLFSVILMEMTRRFSESPEDDIQLLFIDLAQACCRLGIPEEEAVGWTLRY
                     EALKKYKIDIRMAFRTAYTLENVSNRAEPLSSVPPSMSLVLRLDEFMNRRYFFRTNEMS
                     GGVEYLDRSMIQFVYKPYTTKVRNSICLEAQQEGLNVWDKDIDRYVNSDRVPIYHPIDH
                     FLGNLPAWDGKERIRALAGRVPCDNPVWGDLFYRWFLSMVAHWMELDSEHGNSTTPLLV
                     GGQGCGKSTFCLNLLPPVLRPYYTDSIDFGNRRGAELALHRYALINIDEFDSVKSSHQS
                     FLKHILQKAVVNTRLPYQSASRNLRRYATFIATSNNYDLLTDPTGSRRFICVEVKGRID
                     YAQPIDYDQLYAEAKELLRRGERFWFTPEEEALITENNRDFQQQPAEEQLFLRYFKIAE
                     DIEEAKPLLASEILDMIAEKQPGFNITKTMILNFGKLLKRNSVPNKRTMRGTCYYVEEV
                     DG"
     CDS             complement(17348..17734)
                     /locus_tag="ctg66_82"
                     /transl_table=11
                     /translation="MAHYYVVRQKLDKTGAEDKVRYYGVPVTCGRVSTKKLADLVADRC
                     SLSRGDVFASVCEIGGMILELLKDGYSVELDGLGDFYLSAGSEGFEDPKKCTPHRVKAR
                     RVCFRMAPCVRKSMKFVKFERNPW"
     CDS             complement(18337..19056)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_83"
                     /sec_met_domain="Peptidase_M22 (E-value: 2e-23, bitscore:
                     76.9, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSCILNIETSTSVCSVALSMDGEVLFAKASFDGPSHAALLGVFVE
                     EALSVLKKKGKKALDAVAVSSGPGSYTGLRIGVSVAKGLCFGFGIPLIGIHTLDIMAAT
                     VNSKGDSQIVSITDDCLYCAMLDARRMEVYAAIYDASLKPVRETKADIVEAGTYASYLE
                     KGKVCFFGNGASKCKSVITSPNAIFIEDIHPLAVNMIPLSEQAFAAGKFEDTAYFEPFY
                     LKEFQATVAKNKVLLAR"
     CDS             19292..20152
                     /locus_tag="ctg66_84"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKEKEMQI
                     RSLLLQSLERGKVEFNIFVEYIGKDTPTQINLAAVENYYNQIKDIADRLNIGLPADWFQ
                     TLLRMPDVIKTEAQEVNEEEWNVVEKAIKEAIGHLCDFRIQEGAMLQKLFEQKIANISR
                     LLSEVEPYEKERIEKIKARIMDNLEKIAGQDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYYISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKLVVQMKDELEQIKEQ
                     VLNVL"
     CDS             20162..20731
                     /locus_tag="ctg66_85"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINFLLKQNLNLHFSISATSRAPRGTE
                     KDGVEYYFLTPDEFRARIAAGDFLEYEEVYTDKYYGTLKSEVERRLMSGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPSIEDLRSRLEGRGTDAPEVIESRIAKAEFELGFADKFD
                     VIVVNDKLEVAQKEALKVIKEFLKKA"
     CDS             20728..20901
                     /locus_tag="ctg66_86"
                     /transl_table=11
                     /translation="MNGKKLSKKWLYTFIGIAFVALATCTAALYYKEYIIATGTGLVFG
                     AQVINIIKWKRD"
     CDS             20886..21497
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_87"
                     /sec_met_domain="CTP_transf_like (E-value: 3e-24, bitscore:
                     79.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VETGLKENTVSKRKTGIYSGSFNPVHIGHLALANWLCEFTELDEL
                     WFLITPHNPLKEKEELMDDRLRYELVKKSIAGYPKFHASDFEFSLPQPTYTINTLRTLE
                     ASYPDREFYFIMGADNWKYITRWVEYEAIISNYPIFIYPRKGFDVEIPAQYPHIKKVDA
                     PLVEISSTFIREAFKTGKDVRFFLPEAIRNLPFPLQNNTF"
     CDS             21588..23318
                     /locus_tag="ctg66_88"
                     /transl_table=11
                     /translation="MNLLELSEQEIIRRNSMEQLRQMGIEPYPAAEYVTNAFSKEIKEN
                     FKDDAEPRPVSIAGRIMSRRIMGKASFMELQDSEGRIQVYISRDDICPEENKDLYNIVF
                     KKLLDIGDFVGIKGFVFRTQMGEISVHAQEITVLSKSLKPLPVVKYKDGVAYDGFNDPE
                     LRYRQRYVDLVVNDGVKDIFMKRAAVIKTMRTALDEAGYTEVETPILQSIPGGASARPF
                     ITHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMELYV
                     QYKDYNWMMSFTEQLLERICIAVNGTCESVVDGKTINFKAPYRRLPILDAIKEKTGYDL
                     NGKSEDEIRTICKDLNLEIDETMGKGKLIDEIFGEFCEGTFIQPTFIIDYPVEMSPLTK
                     MHRSKPGLTERFELMINGKEVANAYSELNDPIDQEERFKEQLRLSEKGDDEAMFIDQDF
                     LRALQFGMPPTSGIGIGIDRLVMLMTGQTTIQEVLLFPQMRPEKTVKKDTADKYVALGI
                     DEAWVPALHKAGYLTTDTLVDANPNKLRQELCEMNKKYKLELQNPTAEEVEAWIAGAAK
                     "
     CDS             23329..24324
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_89"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 1.1e-32,
                     bitscore: 106.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDQVEEFLL
                     LGHNPSYLSAVKFDTDKIKFYTDINKVIKDSDTLIFATPSPFLKQHLMKVTTSMQDKFI
                     ISAIKGIVPDENMLVADYFAEYYNVPIDNIAVIGGPCHAEEIALERLSYITLACPNIEN
                     ARAFSSVFKNQYLNNSCCKDVTGIEYASVLKNVYAIVAGICHGMKYGDNFLAVFICNAI
                     EEMRNFLNAVHGLERDVTDSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKIAQLEMEM
                     IAEGYYGTKCIREINEKYKVNMPILDTLYSILYEKKSPTTAIRQLTETFK"
ORIGIN
        1 tgccggccat gccccctctt tcgtacagac ataagcagct gtgcggacgg caaattcatg
       61 cgcttccctt agcgaagccc ctttcagcaa cgaaatgacc aatgctccgg agaaagcatc
      121 acctgctcca accgtatccg ccacctgcac ttccggggtt tgcaaagtcg attcttcatt
      181 agcggtatat atcgtactat aagctcctcc ggccgtcaga accaccaagc ggagattata
      241 gtgttctata aaccaatgag ccacctcctt gtccgttcct tccaaatgaa acatatcccg
      301 caggacgacc aactccccgt cattcacctt caacatattt gctagataaa gcgactcttc
      361 gatcaactct ttcgtataat aatgctgacg caaattgatg tcaaaacaac gataagcatc
      421 gtccggggca aaagaaagaa tcgcttgtat cgtctctctt gactgtgcgg aacgctgtcc
      481 taacgtaccg aagcaaatgg catccgcccg ttcggccaaa tcaatcgcat ttgacgtcgg
      541 agaaagatga tcccaagcta cacgttcatt aataatatag tcagggacac catcctgcag
      601 agtaacctgt accgttccgg tcggataagg gactttctcg atcagatacc ggatcgaatt
      661 attatccagt tcttcgagga tttcgcgccc cagcccatcg tctcccacgg cgctgatagc
      721 atatccttcc gcccccaacc gcgacgcgtg gtagacaaaa ttgataggag caccacctgc
      781 tttctttcct gttggcaaca tgtcccacag gagttctcct atgcctacta cgaccggttt
      841 cttattgttg ctttgcattg tttcattata gtttatttga caaggataat ttattatcta
      901 cgatgcaaag atagagacag gtagcagatg cgacgataac taatgctaca agattgataa
      961 cacttgttac attatactct tattttcgag ttacatgcac aaatgttaca caaatgtaac
     1021 gagcgttatc aaagagaaga atattattcc ttttccagat actccgtcgg agtaatattg
     1081 taaacggctt taaaacattt cgagaaataa gcaggcgaac cgaagcccgt cgcataagcc
     1141 acctcattca cattcccggc tttccgtcgg agtagagcag cagctttctt caaacgatag
     1201 ttacgcagga aatcggtcgg tgtcactccg gcaagctcct tcaccttccg gtaaagatgc
     1261 acacgcgaca agcccaattt ttcactacct ttctcaatac tgaaatccgg atcggcatag
     1321 gactcttcga tcagtttcaa gaaacgattc ataaaaagat cgtccatgct tcccgctttt
     1381 tcctccttca cggaaacagc aggcgaagag gcatcgcgag cataagcctc acgcaaccgg
     1441 acacggtcct ccagcagctt gatgatacgc agtttcacga cttctatgtt aaaaggtttc
     1501 tggatatacg cgtccgcacc actggcagcc ccgtacatct gctgtttgtc gtcggacaaa
     1561 gcagtcaaca gcataaccgg aagatggctc aggacaatat ccgacttgat cttacgacaa
     1621 agatcgaaac cgttcatttc cggcatcatc acatcgctga taaccatcga gatatcttcg
     1681 ttcatcagta cctccaaagc cttcacgccg ttatcggcaa ccaacacacg gaagttctgt
     1741 tttaattccg cctgcaagta actctgtata tcaagatcat cttctacgac cagaacagta
     1801 taattgtagg tacggttcaa aacctcctgc aattcatccg tgttcaagtc ggcgacacca
     1861 ctggaaagct cggttacgga aagatcgaat gtacaagatt cgtcaaaatg agatttacct
     1921 ttcaagagga tgaccgtaaa gacagtactc ttatgcggaa cactctccac ccggatcgtg
     1981 cctttgtgca tgtggacgaa ctcacgcgtc aagtgcaggc cgatccccgt tcccgtcaca
     2041 tagttctggt caccggtaaa gaaacggtca aagacggaag caatattttc cgacggaata
     2101 cctttgccat tatcttcgac agaaagctcg acctgatctc ctttatcttt cagatggatc
     2161 gtgaccgtac ctccgtccag cgtgaacttg aatgcattgg acaaaagatt ggccagaatc
     2221 ttctccatct tatctctgtc tacccatata ttaacagaag ggcagtcatg ctcaaacgtg
     2281 aaatgtatct gtttggtggc agccatcgta tcgaaataag atttcacttc tgccacaaaa
     2341 gcaactaaat ctacctctcc gacccgcata ttcatcttat tgctctctac ctttcgaaaa
     2401 tcaagtaact ggtccacgac tctcttcaac ctttccgcat ttttccgaat gatacggata
     2461 tcgtctgcca atgaagaacc ttccggagcc tctttcgaca gcttgccgag cggaccgagg
     2521 atcaacgtca acggcgtctt gatctcgtgt gtgatattgg taaagaattg cagtttctga
     2581 gccgtcgact tctcaatata acggtttgcc tcagccaatt cttctttttg ctgttgcacc
     2641 tgcaagttcg tacgtttcag ctcgcggttc ttccgcttca ccgcccggtt cacatggacc
     2701 acgtacaagg cggacaaaag caacatcccc atcagcaaaa ggataatgcc gacggagttt
     2761 tggaggaacg tgtatttgga aagcatactc tccaaattct cccgttgcaa ctcgatctgg
     2821 tgctgatagt cgaccacctg ttcggactgg ataaacagcg ttccggcatt gttcttatcg
     2881 atcaaggcag aagatagcaa atattgccga gacacatctt ctccgttcaa tatctgcatg
     2941 gctacacgga tagcaaggct cccacccgtc ggatacaaga ccgaagcggc caactctccg
     3001 tgcatgacgg cttccagccc cgatccccgt cccgaaacgg catcgatccc cacaaagcta
     3061 atcctgtccg ccaatccggg atgcatcctt tcgattgccc tgcgggcagc cattgccatc
     3121 acatcattat gggcaaacac aacatccacc tcctccagcg aatccatttc cgctatctcc
     3181 ttctccaccg tttccggctt ccatttcccg aatatttcct tcaccttgat gcgggagttc
     3241 aaaacctcca taaaaccgcg atggcgatcc tgcgccggag aagaaccgga caagccccat
     3301 acttccaata cggtaggata tttctctttc acctgtcggt tcacgaaaaa gccggcctgg
     3361 cgaccgatct cgtaattgtt accaccgata taagtcgtat attcgtccga actgatcttc
     3421 cggtctacca ggatagtcgg aatgccggca cggtaggcct caatcgcaat aggagtgaca
     3481 ggttccgatt cattggcgga gataatcaat agatcgacct tacgttttat caggctgcgt
     3541 atctgctcca cctgcaacag actactgtcc gctgcatcct cgactaacag ggagacgccc
     3601 ggatattcgg aggcctgcac cttcatatcc agcaacatcg atttacgcca agaaccttca
     3661 agcgtacact gcgagacgcc gataacaaac tttttcttct ccgaatctgt tttgcaggaa
     3721 aagcaggatg ccagaagtaa gaccagcaga gcgtaataag ttagagcagg tttcattctg
     3781 ttttatttac aggtttctgc aaatgtacgg agaaatggca taccagccaa tatttatttt
     3841 gtacattcgt cctccagtaa tcaattattc gcatgaagat cataaacgaa gctttattga
     3901 atgaaacgac cgggcgtgcc aaacagtcgc ctcggctacg catgaactac aactttcatg
     3961 agcatttgga cgatcccgtc aaccgtttgc tcaatgccct ggaaccggga acctacctcc
     4021 gcccacaccg ccatctgaac cctaaaaaag atgaaatatt cctcctgctg cgcggtcgca
     4081 ttgctgtatt cctctttgac aacaaagggg aaatcaccca aacacagata ctcgatccga
     4141 aagaaggtgt ttacggcgcc gaaataaagg cgggaacatg gcacgggctg ttagttctag
     4201 aatccggctc tatcatatat gaaatcaagg aagggccgtt cgctccgctc gctccggaaa
     4261 atttcgctcc ctggagtccg gctccagaag acacgaaagg ggtggcaaaa tatatggagt
     4321 tattaggaaa ggctatataa ccttgcacta ccttcccgtt ccccttaaag aaaactttat
     4381 tttcatgcaa gggaaacttt attttcatag ggatgaaact tctttttcat ccccatgaaa
     4441 ctgttatcac atacctatcg gctcctttat tgctggaata cttttgtcaa acggatcatg
     4501 gcttctttca ccggacagtc attcttatcc gttctgacaa tagcgttctc ataattttca
     4561 actttcaaat accaacatct gacaatgctt gcagtcgaac tgcaaccgga ggcgcgtatc
     4621 tttataaagc agataatacg gttccttgta gggagacttg tctttttgat aagtaggaca
     4681 ccaccccatg ctgtagcgca ggcagtgttt ggtaaacatc aacggaacat ctttccgggg
     4741 agacagttca aatgccgggt caatctgttc caccccgtga tcctggtaga acgaacgggc
     4801 tttcccgttg gcaacattcc ccaaataagt aagttggcgt tcggggaaag gtatcgacac
     4861 ggacggctgc acacgtttca ctgtctcacg aggatagcgg gcacggcgtg cttccagcaa
     4921 cttctccact cctctacggc gcatatcggc aagcagagaa gagggaacga accagttttc
     4981 agacaaaccg accaccacct tcgatgcctc gaaaggcgta ttccccaact tggatagctg
     5041 tgtccgtata ttatcctgct gttcatgacg cgccagctct ttcgcaaacg gctcggtcag
     5101 catgatccgt gctcccgtct catcctccat acaaagcgta aaaccgaagg gattgtccaa
     5161 gaactcgatc tccacggaca gcttgcgttc ggctgaaggc ttggcgagca gtttatcaaa
     5221 tgcctggtcg aaattgcggt aaagcggagt cttgggggta agctgcggca tatccagcgg
     5281 aaacacccgg tttgcctcca cccggtttac acgaaaacct tccaattcgc ctttcctatt
     5341 gaagaaaaca agcccgtctc cgttgctcag ctgcttcaag ccagccacag taaaagaatt
     5401 gcctttgatc tctttgaccg tcccgacagg ttcacccagc gatttaggcg tattgaaagc
     5461 ggtaatatcc gccgtccgtc cctccaaaag gaacggggtg aacccacggt taaaactctt
     5521 ttcagctacc ggctcgaacg tataagtgct tcgaccagca gaagcacgac gatattccgg
     5581 acggcgggac aggactgcat ctaacttctt ccgataataa gccgtgatat tcttgacata
     5641 gccgacatct ttcaaccgcc cttcgatctt gagggaagaa acacctgcat ccaacagggc
     5701 ttccagctga tcggagcggt tcatgtcctt gagcgaaagc aagtgtttat gggtgacgat
     5761 ctccgtccct gtcgcatcga ccatcgtata gggcaggcgg caatattggg cgcattctcc
     5821 gcgattggca ctacgtccac tcaaagcggc gctcagataa cattgcccgc tatagctgac
     5881 gcagagggcg ccgtgcacga atacttccag cggaacggta gtcgcttccg atatccggcg
     5941 aatctcgttc agcgacaatt cacgtgccag aaccacctgt gtaaagcctg cggcttcgag
     6001 gaaacggacc ttttccggtg tacgattgtc cgtctgcgtg ctggcgtgaa gcggaatagg
     6061 aggcaggttc agccgggtaa tccccatatc ctgaatgatc agggcatccg tcccgacacg
     6121 ccagagatcc cagatcatcc gttcggcttc ttccaactca tcttctttca atatcgtgtt
     6181 aagcgtaaca tagatgcggg cgccatacag atgcgcatac tcgcaaagct cgcgtatatc
     6241 ttccaaagag ttgccggcag cagcacgcgc accgaacttg ggtgcaccga tatagacggc
     6301 atcggcaccg tgattaatcg cttcaatccc gcaattgagg tctttagccg gagagagaag
     6361 ttctatagga cgggattttg tttgcatgct attatttctt atttcttgat tacaaatcac
     6421 ccaacttgct gatatcctcg atacggaacg gggtttcctg atagacataa tagttcagcc
     6481 agttggtgaa cagaagattg gcatgaccac gccagcggac caccggaccg agggccggat
     6541 tgttattacg gtaatagtta cggggaacgg caattggcaa tcccttgttc acgtcgcgca
     6601 tatactcgtc attcagcgtg taaggcgagt attcggaatg cccggtgata aaaaactcgc
     6661 gtcctccgcg cgccatcgcc atatagacac cagactcttc gctttcggac aagagcgtca
     6721 aatcgggaac tttcatcaca tcctcgcggc gtatctccgt atgccggctg tgcggcacat
     6781 agaactcgtc gtcgaagcct cggaagatcg gcacataggg ctcgcgcaac gtatggcgga
     6841 acacgccgaa catcttggct ggcagatcat atttggggac accataaaaa tggtacaacc
     6901 cggcttgcgc cgcccagcat atatataagg tagaagtcac atgcgtacgc gcccaatcga
     6961 atatctcggt cacttcctcc caatagttca cttcctcgaa aggcatctgc tctaccggag
     7021 cacctgtgat aatcatgccg tcgtaaaaat catcctgcat ctcgtcaaag tctttataga
     7081 attccttcat atgctcgatc ggcgtgttct tgggagtatg gccttttatc ttcataaagt
     7141 cgagctccac ttgcaagggg gtattgctca agaggcgaac aaggtccgtc tccgtcgtga
     7201 tcttcagtgg catcaagttc agcacaacta cacgtagcgg acgaatgtcc tgctcagacg
     7261 cacgcaacga gtccatcaca aagatgtgct ctttcttcaa cagctcaaca gctggcaagt
     7321 tcttctgtag gtttaaaggc atcttctttc cttaattatt tatataaggc acaaagatag
     7381 tgagaaattg cctttcattg aaaataaatc gttgtttccc gcgtttgtag atttaataat
     7441 tagatggaat atgaagattc gtgcaatagc tacactacta tttatattat tttcgataag
     7501 tgctttcggg cagggacgtg ccaaaatcag cggttatatc cgcgacgcgg acggtaatcc
     7561 gctggacttg gtcaatatcc gggtcaagaa cacgttaaac gggacgatga gtaatgaaaa
     7621 aggccactac tcgctttcgg tcgctaccgg tgactcggtg acgcttatct attcatgcct
     7681 gggctacaac aaggccgaaa ggatcctacc tcaggtaacc aaagatatgc gtctcaacgt
     7741 gcagatgaac tatacatcac tcgaactggg agaagtcgta gctaccgcca tccgaaagca
     7801 gacaaccacc cttgaaaccc tgaatgccga ccgcgtcaaa ctactccccg accctgccgg
     7861 aggaagcatt gaaagtctgg tcgttacatt tgctggcgtt acttccaata acgaattaag
     7921 ttcgcaatac tccgtacgcg gcggcagcta tgacgaaaac atcgtatatg tgaacggact
     7981 ggaagtgttc cgtccgctgc tcatccgttc cggacaacag gaagggttga gttttatcaa
     8041 cccggacatg acggaagccg tcaatttctc cgccggagga ttcgaagccc gttatgggga
     8101 caagatgagt tccgtgctgg acatcaccta caaaaaaccg aaaggattcg aaggttcggc
     8161 ttccgccagc ctgctgggag ccaatgctta tgtgggcagt tcttccggca agttcacaca
     8221 ggtgaccggt ttccgttaca aaacaggacg atctcttttg aaaacaaccg atacggatgc
     8281 cgaatatgat cctaatttca ttgatttgca gacttatatg acataccagc ttgcccccaa
     8341 atgggagatc aactttctcg gaaacttagc cataaacaat tataagttca ttccccacac
     8401 ccgagagact tcttttggaa cggcaacaaa tgccaaaaaa tttaaagtat tcatgagtgg
     8461 ccaggaacgg gataagttcg aaacgttatt cggagcactc actttaaagc ataacctgaa
     8521 cgacaatacg gaactcggct tgcaagcatc cgcctttacc agtaaggaag aggaaggata
     8581 tgatattgcc ggtgattact ggctgggaga tgcagccgaa gaaggaggcg gagaaataca
     8641 gaaattatcc atcgcacgct ataacgagca cgctcgcaac cgtctgcact ccaatatcat
     8701 gaatgtcggg cattatggtg tcgctcgcat aaaaaacaat acgttgaaat ggggtgctac
     8761 cgtccagttg gagaaaatca acgacaagat cagcgaatgg gaaaaacgcg actccgccgg
     8821 atactcgtta ccgcaagggg gcgggaatgt caacgtgatc gcaaacctgt tctcggataa
     8881 caaactggaa agcacacgta tttccggcta tttgcaggat gtattcaagt ttcgtaccaa
     8941 acaaggactg ttcacgctgg ttggtggtgt acgcggcagc tattggagtt ataacaggga
     9001 atttatattc agcccgcgtg cttcaatagg tttcattccg aacttcgacc agaacctgac
     9061 atttcggctg gcttccggtc tgtattatca gtctccgttc tataaggaat tacgtacaac
     9121 tgtgcaggac gaacacggca acagtatcat acaactgaac aaaaacctga aatcacagcg
     9181 ttccatccat gtcattgcag gaggcgatta tacattccgg gcatccggca gaaatttcaa
     9241 agtcagtgcc gatatgtatt ataaaaaatt ggataacctg aacccctata cggtggataa
     9301 tgtcaaaatc cgatactacg gcgagaactg tgcacaaggc catgcgatgg ggctcgatgt
     9361 caaattcttc ggcgaatttg ttccgggtac ggactcctgg atcagcttct ccctaatgaa
     9421 agcggagcaa agcatccgag ggagcgaata tgtaccgatg cctaacagcc aaggttataa
     9481 tgtctcgctc ttttttcagg attatttccc cggatacaaa cgtgtcaaat tgaatctgaa
     9541 aggcgtactg tccggcggcc ttcccgtcac agccccacgt acaggctacg aggacggcta
     9601 tttccgtact ccgacctaca aacgcgtgga cctcggtttc tcctaccagc ttgccggggg
     9661 aacggatgca atcatggatc gcggattctt ccgcaatctc aagaacattt ggctcggatt
     9721 ggatattttc aacttgttcg acataaagaa cactagttcc tattattgga ttaccaatat
     9781 agacaaccac cagtacgcaa tccctaatta cctgaccgga agacaattga atattcgact
     9841 tatcgttgat ttttaaccac atgatttcaa aaatatgctt tttaaacata tccggatcat
     9901 gctgataaat attaacgaat tatttctcta ttaataaaaa gagtgtacct ttgccaacat
     9961 agaacaaaaa gcaatattaa attactaaat tattattgac atggaactta cacatatcga
    10021 acatttgggt atcgcagtaa agagcatcga agcttgcctg ccgtattatg aagaagtttt
    10081 aggactaaaa tgctacaaca tcgaagaagt agcagaccag aaagtaaaaa ctgcattctt
    10141 taaagtaggc cagactaaga tcgagttgct ggagccgaca agtgaagaca gtacaatcgc
    10201 taaatttatc gaaaagaaag gtgaaggtat ccaccacatt gcatttgctg ttcccgacgt
    10261 acaggcagca ttggacgaag ccgaatcaaa aggtgtcaag ctgatcgaca aagctcctcg
    10321 tggaggtgca gaaggcttga acattgcatt ccttcacccg aaatcgacat gcagcgttct
    10381 gaccgaactt tgcatgccgg gaaaataaga aacaatggac aattgagaat tgacaattat
    10441 ttgatgctat tcaattgtca attctcaatc gtcaattgcc aattaaataa gttcatttct
    10501 aacaacaaat ctatagtaca atgagtaacc aacttgaaaa agtaaaggag cttatcgccc
    10561 ttcgcgaaac agctcgttta ggtggtggag aaaaaagaat cgaatctcag cacaaaaaag
    10621 gtaaatacac cgcacgcgaa cgtattgcca tgttgctgga tgagggaagt tttgaagaat
    10681 tcgatatgtt cgtacaacat cgttgtacaa acttcggtat tgaaaaaact aagtatttgg
    10741 gcgacggtat cgtaacaggt tacggaacga tcgacggacg tctggtatat atttatgctc
    10801 aggatttcac cgtgttcggc ggtgctttat ccgaagcact ggccatgaag atctgtaaag
    10861 taatggatca ggcgatgaaa atgggtgctc ccgttattgg cttgaacgac tcgggtggcg
    10921 cacgtatcca ggaaggtgtc aacgccttgg ccggttatgc agaaatcttc caacgtaaca
    10981 tcttggcttc cggggttatt cctcagattt ccggtatctt cggtccatgt gccggcggtg
    11041 cggtttactc tcctgccctg acagacttca atatcatgac ccgcggaaca agttacatgt
    11101 tcctgactgg tccgaaagta gtaaaaacag ttacaggcga agatgttaca caggaacaat
    11161 taggtggcgc aagcgtacat acgaccaaat ccggtgtggc ccacttcgca gtcgatacgg
    11221 aagaagacgg tttacagttg atccgcaaat tgatcagctt cctgccgcag aacaacctgg
    11281 aagaaactcc tctgatcgaa tgtaaagacc cgatcgaccg tctggatgac aacctgaacg
    11341 acatcatccc tgacaatcct aaccaggctt acgatatgta tgaagttatc ggaaccatca
    11401 tcgataacgg cgaatttctg gaagtacatg ccgactatgc caagaacatt atcgtcggtt
    11461 tcgcccgttt taacggccag actgtcggta tcgtagccaa ccagccgaaa gtaatggcag
    11521 gctgtctgga cagcaacgcc tcccgcaagg caggccgttt cgtccgtttc tgtgatgctt
    11581 tcaacattcc tttggttaca ttggttgacg taccgggatt cttaccgggt acaggccagg
    11641 aatacaacgg cgttatcctg cacggagcca aattgcttta cgcttacggc gaagccacag
    11701 tgcctaaagt aactgtaaca ttgcgtaaat cttacggtgg agcctattgt gtgatgagct
    11761 ccaaacatct gcgtggcgat atgaactacg catggccgac agccgaaatc gcagttatgg
    11821 gcccaagcgg cgctgtagaa gtgatctttg caaaagaagt ggctgcctcg gaagatccga
    11881 aagcttgcgc tgcagaaaaa gaagccgaat acaaaaaagc atttgcaaac ccatacaatg
    11941 cagctcaata tggctatatc gacgatgtta tcgaacctcg taacactcgt ttccgtatta
    12001 ttcgtgcttt acaacaattg cagaccaaga agttaagcaa tcctgccaag aaacatgaca
    12061 atctgcctct ataattctta aaacaggaaa tgaatatgat taataagaaa ataggggtat
    12121 tgctgctgtt cgcgttgctc gtttcattcg gagcaaaagc acagcgtgca acctccatgc
    12181 gaataaatga agtgctggtc atcaacgaag ataactttgt tgatgattac ggcaaacgcc
    12241 atgcctggat cgaattgttc aacaattcgg ccggttcggt caatatcgcc ggttgctact
    12301 tgactaatga caagagcaac ccgaaaaagt atccgattcc gaagggcgac gttctaacag
    12361 taattcctcc tcgccagcac actttgttct gggcagacgg agaaccggat cggggaacat
    12421 tccatgtcaa tttcacgctc gacccatcaa aagaaaatta cattgcgtta tacgatgcag
    12481 acggtaaaac tctgatcgat gagatcgtta tccctgcttc acaaaaagca gatgtcagct
    12541 atggtagaac tttagacgga caaggtgaat ggactgctct gacaaaagtt acacccagca
    12601 ccaataacgt aacattggat tctaacgaga aaatcgagaa ctttaaagaa aatgattctt
    12661 ggggtatcgg tatgaccctg actgccatgg cagttgtgtt ctccggatta ttcctgttgt
    12721 tcatcatctt taaacaaatc ggaaagctct cgatcgcggc cagcaaacgc aatgcacaga
    12781 aagcggccgg agcggctgtt attgcagaca atgcaggtca ggaatccggg gaaatctttg
    12841 cggctatcgg tgcggctcta tacgaaatga gcgacgacaa ccacgacatc gaacatacgg
    12901 ttctgacgat ccgcaaggtt caaagatctt attctccgtg gagttccaag atttacggtc
    12961 tgcgtgaagt tcccaaaaag taattatctc taaaaacaaa caagaatgaa aagttttaaa
    13021 tatactatta acggtaacgt atataaagta catatcagct cggtagtgga tgacatcgct
    13081 gaagtagaag taaacggtac tccctatcaa gtaaaaatgg agaaaccggc aaaaaaacag
    13141 atggttacac tgaaacgccc ggctcaagct cctacaacgg caagtggcga accggttatt
    13201 tcccgtccgg cagcctcaac caccaagggc gctgtcaaat ctccgctgcc aggtgtaatc
    13261 ctgcaggtta actgtaaagt cggtgatact gtcaagagag gccagaatct acttgtcctc
    13321 gaagccatga agatggaaaa caacatcaat gccgaccgtg acggcaaaat cattgaaata
    13381 aaagtaaaca aaggggattc cgtactggaa ggtgctgacc tcgtcgtaat aggataatat
    13441 tatgttagga tcagtattat tacaggcagc gggtacggct catgaaagct ttctccagtt
    13501 cttgggagaa aacttggagt tgttcctcac ttatacagga gtctacaacg cgacaccggg
    13561 tcaccttatc atgatccttg tcggtctgtt gttcatcttc ctggctatta aatatgaatt
    13621 cgagcctatg ctccttatcc ctatcggatt cggtatcctg atcggtaaca ttccgttcaa
    13681 agatgcagga ttgcaggtgg gtatttacga acaaggttct gtgctgaaca tcctctacca
    13741 gggtgtaacc tccggatggt atccgccgtt gatcttcctc ggtatcgggg ccatgaccga
    13801 tttctccgca ttgatctcca atcctaaact gatgttgatc ggtgcagcgg ctcagttcgg
    13861 tattttcgga gcatatatca tcgctcttca aatgggattt gaaccgaacc aggccggtgc
    13921 aatcggtatc atcggtggtg ccgacggccc gacagcaatc ttcctttctt ccaagttagc
    13981 tccgaacttg atgggtgcta ttgcagtatc ggcatactct tatatggcgc tggttcctat
    14041 tatccagcct ccgttcatgc gcctgctgac gactcagaaa gaacgtctga tccgcatgaa
    14101 accgccgaga gccgtttctt ccacggaaaa gatcgtattc ccgatcgtag gcctgttgct
    14161 gacttgcttc cttgttcctt ccggtctgcc tctgttgggt atgctgttct tcggaaattt
    14221 gttgaaagaa agtggtgtaa cacgtcgttt ggctgaaaca gcccgtggtc cgctgatcga
    14281 tacgatcacg atcctgttag gtattacggt aggtgcttct actcaagcaa cccagttcct
    14341 gacattgaac tccatcaaga tcttcggttt gggagcgttg tcattcgtga tcgcaacttg
    14401 tgcaggtatc ctgttcgtga agttcttcaa cctgttcttg aaagaaggca ataagatcaa
    14461 tccgcttatc ggtaactccg gtgtgtctgc cgtgcccgac tctgcccgta tctctcagaa
    14521 cgtaggtctg gaatatgatc cgaccaacta cctgttgatg cacgccatgg gtccgaacgt
    14581 agcaggtgta atcggttctg ccgtagcagc cggtatcctg ttgggattct taggataatc
    14641 cacttattct acataaaaag gagctgaact ccaagtcatc tccaaatata aaaacttacc
    14701 caagtttacg gattttaacg tattcttggg taagtttgta tatgcgcaca acgattcatc
    14761 agaagtatat taatggctgt atcataaaaa actatttacg acacagcctc cctttttata
    14821 tccgacctta tcagatattt tgttcgacgg tcatcggatc tgtctctgga tttgcctcct
    14881 gttccaatgt tgtccccaaa aacaaccaaa tcattaacag gataatcgcg atcaccacac
    14941 caaagaccag cagtacattc gtattctttc gtctcatgtc tattcttcaa tattgatttg
    15001 aagattaaac aagacacccc cttttttggt ttaaccgttc cttacttttg ttctttattt
    15061 aactgagtaa atattttaga aagaatgttt tttcttcact tacaaatata gttggaaata
    15121 gacgatccaa ctatcatacc atcataattg gcaataaccc actatatatc aacacaaaat
    15181 agccatgaca gttcgcaaaa caactgtcat ggctactatc ataccatcat acataaaatt
    15241 agtcaatcaa ttatatatca accatctacc tcttccacat aataacaagt ccccctcatc
    15301 gtccgcttat tcggcacgct attccgcttc aaaagcttgc cgaaattaag gatcatcgtt
    15361 tttgtaatgt taaaaccggg ttgtttctcc gcgatcatat ccagtatctc ggacgccaga
    15421 agcggctttg cctcttcaat atcctccgca atcttgaaat aacgcaggaa cagttgctct
    15481 tcagccggct gctgctggaa atccctgttg ttttcagtga tcagcgcctc ttcctccgga
    15541 gtaaaccaaa aacgttcacc acgcctcaac aattctttcg cttccgcata caactgatca
    15601 taatcgatcg gctgggcata atcgatccgg cccttcacct ccacgcaaat gaaacggcgg
    15661 ctaccggtcg gatctgtcag caaatcataa ttgttgctgg tcgcgataaa cgtggcatag
    15721 cgacgcaagt tacggctcgc actctgataa ggcaaacggg tgttcacaac cgctttttgc
    15781 aggatatgct tcaaaaaact ttgatgagaa cttttcactg aatcaaattc atcgatatta
    15841 atcaacgcat accggtgcaa agccaactcc gccccacggc gattgccgaa atcgatactg
    15901 tccgtataat aaggacgcaa cactggtggc aacaaattca agcaaaacgt ggacttccca
    15961 cacccttggc caccgaccaa cagaggtgtc gtactattcc cgtgttccga atccagttcc
    16021 atccaatgtg ccaccatgct taggaaccag cggtaaaaca aatctcccca taccggattg
    16081 tcacaaggga cacgcccggc taatgccctg atgcgttctt ttccgtccca agccggaaga
    16141 ttcccaagaa aatgatcgat aggatgatat atcggaacac gatcggagtt gacatatcgg
    16201 tcgatatcct tgtcccatac attcaaccct tcctgctggg cttccaggca aatggaattc
    16261 cggactttcg tcgtataagg cttgtaaacg aactgtatca tcgaacggtc caaatattcc
    16321 actccaccgc tcatctcatt cgtccggaag aaataacgcc ggttcataaa ctcgtccaac
    16381 cgcaacacca acgacatgga tggcgggacg gaagagagcg gctccgcccg gtttgaaaca
    16441 ttctccaacg tatatgccgt acggaaagcc atacggatgt ctatcttata ttttttcaaa
    16501 gcttcatagc gcaatgtcca gcccaccgcc tcttcctccg gtattccaag ccggcagcaa
    16561 gcctgcgcca agtcgatgaa cagcagttgg atatcatctt ccgggctttc tgaaaaccga
    16621 cgcgtcatct ccatcaggat gacactgaac agcgtggcga tctgcccgtt ccgatccgct
    16681 cccggagcca tcatctccaa cggatcccga accggagaag gcacgatctt caagtcaccc
    16741 ccgtccggca tctgcaaagg ttgctcgatc cggatcgcca ccgcatccgg attgtaatag
    16801 gcgtccggat ccacactcat ccggcacccc cgcgacagga acggttcttt caacgatata
    16861 atgctgccca actgcggctg gtaatgccgc accgccagct gataagccgc agcatgaaac
    16921 atacgggcct gctcctcttt tttcggcagc gagccgtcgg gcagcacaaa aggaaccacg
    16981 atcttgaccg aacgcccgct cagcccgacg aacgccagca aggtctgcgg cagggcggca
    17041 gcttcacggc ggacggcctc cgcctcactc tggctttcca agccgttcac ttccaacaag
    17101 acatacccgt tatagcgcct caactgtatt ccatcgccat tcttcttgaa cgtcgagcca
    17161 aaagccagga ccggtagttt tccggacaaa tccgtggttc gtgccaaaaa cgccatattc
    17221 aattttcgac gaaccgacag tatcgcttcc gcatctttgc cgtttttcag caacccgaca
    17281 atatattcca tatcacgcga gtgcatccgc aacacgcctt ttttatgcct gtaatatgtg
    17341 atttgcatta ccaaggattt ctttcgaatt tgacaaattt catgctcttt ctcacacagg
    17401 gagccatcct gaaacagaca cgacgcgcct tcacccgatg gggagtacat tttttcggat
    17461 cttcgaagcc ttcgcttcct gccgacagat aaaaatcacc caacccgtcc aactccacgg
    17521 aatagccgtc tttcaacaat tcaagaatca tccctccgat ctcgcaaacc gaagcgaaca
    17581 catcacctcg gctcaacgag caacgatcgg caaccaaatc agccagcttt ttcgttgaaa
    17641 cccgcccgca cgtaaccgga acaccataat agcgtacttt atcttccgct cccgtcttgt
    17701 ccagtttttg ccggactaca tagtaatgtg ccataaataa cagtattttt aatattaaac
    17761 aaccagatat tcttctcaag acgcccattt taacactttt gacaccccca tctgaacggt
    17821 atcaacaccc gggtctcacc ccttccgaca cccggatgac gggcttcttt tcttattaca
    17881 aatatacaaa taaaacatct ataatgcaaa tatttacagc actttattca attatatcta
    17941 cacttatttt tccccagcac gaagacagaa gcatgtgata tacgacatga tagtatgata
    18001 gtatgaaatg atagttgaaa atagatacta tcatattttt ataaactaat atacagacat
    18061 ttataagaaa atatgatagt atgatagttg gatttaaaaa aaatcatatg tatataatag
    18121 gtggatgttt acagcagttt atttatattg cttgcaggag gaagacttac atggatggca
    18181 accctaaata acacatcgtc ctgtttccat gtttgacatt gcagctatca aacacaagaa
    18241 acaggacgat tttgcatatc taagttcttt tccgattgac cggacttaca taaaaatttc
    18301 gacaaacgtg ccattccgac atagcacaca actacatcat cgagctaaaa gcaccttatt
    18361 ttttgcaacc gtcgcctgga actctttcag gtagaacggt tcgaaatagg cggtgtcttc
    18421 aaacttgccg gcggcaaaag cttgttccga gagcggaatc atgtttacgg caagaggatg
    18481 gatgtcctcg ataaagatgg cgttcggaga agtgatgacc gatttgcatt tggaagcacc
    18541 gttgccaaag aaacaaactt tccctttttc cagataagaa gcatacgtac cggcttccac
    18601 aatatcggcc ttcgtctcgc ggacaggctt taaggaagca tcgtagatag cggcataaac
    18661 ctccatacgc cgggcatcca acatagcaca ataaaggcaa tcatcagtaa tagagacgat
    18721 ttgcgaatca cccttactgt tgacagtagc agccatgatg tccaacgtat gaatgccgat
    18781 cagaggaata ccgaaaccaa agcaaagacc tttagcgaca gacactccga tacggagtcc
    18841 ggtataagaa ccaggaccgc tactgaccgc tacggcatcc aaggctttct tccccttctt
    18901 tttcaatacg gaaagagctt cttcaacaaa tacgcctaat aaggctgcat gcgaagggcc
    18961 gtcgaacgag gccttcgcaa aaaggacttc accatccata gacaacgcta cagagcatac
    19021 agaagtcgat gtttcgatat ttaatataca agacatttta attgacaatt gacaattgac
    19081 aattgacaat taaaatatgt gtcaaaagcc aatcggttga taatggatgc aaaagtataa
    19141 aacataactg taatctcatg atcaaaaccg attttattaa ggctgacacg gatggtttcg
    19201 gctttttctc aattatattg tcaatcgtca attgtcaatt atcaattgat tagctatctt
    19261 tgcacaaatt tttagaacaa tgatacaatc aatgactgga ttcggtaagg ttacagccga
    19321 acttccttct aaaaaagtaa ccgtagaaat aaaagctctg aacagcaagc aactggattt
    19381 gtcgacccgc attccttcca tctacaaaga aaaagaaatg caaatacgca gtttgttact
    19441 ccagtcgctt gaacgtggaa aagtcgaatt taatatattt gtcgaatata tcggtaaaga
    19501 cacgcccaca cagatcaact tggctgcggt agaaaactat tacaatcaaa tcaaagatat
    19561 tgccgaccgc ctgaacatcg gacttcccgc cgactggttc cagaccctgc tccgcatgcc
    19621 ggacgtgatc aagacagagg cccaggaagt aaacgaagag gaatggaatg tggttgagaa
    19681 agcgatcaaa gaggccatag ggcacctttg cgatttccgt attcaggaag gcgccatgtt
    19741 acaaaagttg ttcgaacaga aaattgccaa tatctcccgc ctgctttcag aagtagaacc
    19801 gtatgaaaag gagcggatcg aaaaaatcaa agcccgtatc atggacaatc tcgaaaagat
    19861 tgccggacag gactacgaca agaaccggtt cgaacaggag atgatctatt atatcgaaaa
    19921 actggatgta aacgaggaaa agaaccgcct ggacaaccac ctgaaatatt acatcagcac
    19981 gatggagagc ggacacggac aaggtaagaa actcggtttc atcgcccagg aaatgggacg
    20041 tgaaatcaac acccttggtt cgaaaagcaa ccatgccgag atgcaaaaac ttgtcgtcca
    20101 gatgaaagac gaactggaac aaatcaaaga acaagtatta aacgtattat aaaaacgata
    20161 tatggctggc aaactgatca tattctccgc gccgtccggt tcgggcaaat ccactatcat
    20221 caatttcctg ctgaagcaga atctgaacct gcatttttcc atctcggcta ccagccgggc
    20281 cccacgtggt acggaaaagg acggagtgga atattatttc cttacaccgg atgaattccg
    20341 tgcccgtata gcagcaggag atttcctgga atacgaagag gtctataccg acaaatatta
    20401 cggcacgctg aaaagcgagg tggaacgaag gctgatgagt ggcgataacg tcatattcga
    20461 tgtcgatgtc gtaggaggtt gcaacatcaa gaagttttat ggcgaccgtg ctctttcggt
    20521 ctttatccag cccccctcga tcgaagattt gcggagtcgt ctggaaggac gcggtacgga
    20581 tgctccggaa gtaatcgaaa gccgcattgc caaagccgaa tttgaactgg gttttgccga
    20641 caaatttgac gtaatcgtgg tgaacgacaa gctggaagtc gcacaaaaag aagcactaaa
    20701 agtgataaaa gagttcctta aaaaagcatg aacggcaaga agttatccaa gaaatggcta
    20761 tatacattca ttggtatagc atttgtcgct cttgccactt gtacagccgc cctatattat
    20821 aaggagtata tcatagcgac cggtaccgga ttggtattcg gtgcacaagt cataaatatc
    20881 atcaagtgga aacgggactg aaagaaaata cggtcagcaa acgtaaaacc ggcatttatt
    20941 ccggttcatt caatccggtt catatcggcc atctggcatt agccaactgg ttgtgtgaat
    21001 ttacggagct ggacgagcta tggtttctga tcacccccca taacccgcta aaagagaagg
    21061 aagaactgat ggatgaccgg cttcgctatg aactggttaa aaaatccatc gctggttacc
    21121 ctaagttcca cgccagtgac ttcgagtttt cccttcctca acccacttat accatcaaca
    21181 cactccggac attggaagca agttatccgg accgtgaatt ctatttcatc atgggtgcgg
    21241 acaattggaa atatattacc cggtgggtag aatacgaagc catcatttcc aattatccga
    21301 tcttcatcta tccgcgtaaa ggattcgatg ttgaaattcc ggcacaatat cctcacataa
    21361 aaaaagtaga cgcccctttg gtcgaaatat cctcaacctt tatacgcgaa gctttcaaga
    21421 ccggaaaaga tgtccgcttc ttcctgcccg aagccatacg taatctgcct tttccattac
    21481 aaaacaatac cttttaagaa cataaagcgt aaagtcgcat acgtttttag gcaataagta
    21541 agaaaagttt tgtatttttg cgccgtatta tacaaaataa tagcgtaatg aatctattag
    21601 aactgagtga acaggaaatc ataagacgta acagcatgga gcagttacgt cagatgggga
    21661 tagaacctta tcccgcagct gagtatgtaa cgaatgcatt ttccaaagag ataaaagaga
    21721 attttaaaga cgatgcagag ccccgccccg taagtattgc cggccgcatc atgagccgcc
    21781 gcatcatggg aaaggcttcc ttcatggaat tgcaggattc agaaggcaga atacaggttt
    21841 atatctctcg tgacgacatt tgcccggaag aaaataaaga tctgtataac attgttttca
    21901 agaaattgct cgatatcggc gactttgtcg gaatcaaagg tttcgtattc cgtacacaga
    21961 tgggcgaaat ttccgtccat gcacaagaga taacggtatt atccaaatca ctcaagccgc
    22021 taccggtcgt caaatacaaa gacggtgtag catacgatgg attcaacgat ccggaattgc
    22081 gttatcgcca acgctatgtc gacctggtgg tcaatgatgg cgtaaaggat attttcatga
    22141 aacgtgcggc agttatcaag accatgcgta ccgcgctgga cgaagctgga tatacggaag
    22201 tggaaactcc gatcctgcaa tccatccccg gaggggcaag cgcacgtccg ttcattacgc
    22261 accataactc gctggatatc gacctctatc tgcgtattgc taccgaactg tatctgaaac
    22321 gattgatcgt cggaggtttc gaaggtgtct acgaaatcgg taaaaacttc cgtaacgaag
    22381 gtatggatcg cacccacaat ccggaattta cctgtatgga actttatgtc caatataagg
    22441 actacaactg gatgatgagc ttcaccgaac agctgttgga acgtatctgt atcgccgtca
    22501 acggtacatg tgaaagtgta gtcgacggca agaccatcaa ctttaaagct ccttaccgcc
    22561 gtctgccgat tctggatgcc atcaaggaaa agacaggtta cgacctgaat ggcaagagcg
    22621 aagacgagat acgcacgatt tgcaaggatt tgaaccttga aatcgatgaa acaatgggta
    22681 aaggcaagct gatcgatgaa atcttcggtg aattctgcga aggcacgttt atccagccga
    22741 ctttcattat cgactacccg gtcgagatga gtccgctaac caagatgcac cggagcaaac
    22801 ctggattgac cgaacgtttc gaattgatga tcaacggtaa agaagtggca aatgcctata
    22861 gtgagctgaa cgatccgatc gatcaggaag agcgcttcaa agagcaattg cgcctgagcg
    22921 aaaaaggaga tgacgaagcg atgttcatcg accaggactt tttgcgtgca ctgcaattcg
    22981 gtatgcctcc gacgtctggt atcggtatcg gcatcgaccg tctggtgatg ttgatgactg
    23041 gccaaacaac tattcaagaa gtgttgctct tcccgcagat gcgcccggaa aagacagtta
    23101 agaaagacac cgcagacaaa tatgtcgcac tgggtatcga tgaagcatgg gttcctgctt
    23161 tacataaagc cggatatctc acaaccgaca cgttggtaga tgctaatccc aacaagctga
    23221 gacaggaact ctgcgaaatg aataagaaat acaaactgga attgcaaaac cccactgccg
    23281 aagaagtaga ggcatggatt gcaggcgcag ccaaataaga gtaatactat gaagttgccc
    23341 ggaaaaattg caataatggg aggtggtagc tgggctaccg ccttagccaa gattgtactt
    23401 tctacacaag atagtattaa ctggtatatg cgtcggccag accaagtaga agagtttctg
    23461 ttgttgggac ataaccccag ctatctttcc gccgtcaaat ttgatactga caaaatcaaa
    23521 ttctacacgg atatcaacaa agtaatcaaa gattcggaca ctttgatttt cgccacccct
    23581 tctccttttt tgaaacaaca tttgatgaag gtgacgacct ccatgcaaga caaattcatc
    23641 atttcggcca tcaaaggaat cgttccggac gaaaacatgc tcgtagccga ttattttgcc
    23701 gaatactaca atgtcccgat tgacaatatc gctgtcatcg gcggtccgtg ccatgccgaa
    23761 gagatcgctc tcgaacggtt gtcctatatc acgctggctt gccctaatat cgagaatgca
    23821 agagctttct cctccgtatt taagaaccag tatctgaaca actcctgttg caaggatgtt
    23881 acaggtattg aatatgcttc cgtattgaaa aacgtatatg ctatcgtcgc aggtatctgc
    23941 cacggtatga agtacggaga taattttctg gcagttttca tctgcaacgc gatcgaagag
    24001 atgcgtaact tcctcaacgc cgtacatggc ctggaacggg atgtgacaga ttcggtatat
    24061 ctcggtgatc ttctggtaac cgcatattct cgcttcagcc ggaaccgtac gttcgggacc
    24121 atgatcggga aaggttattc cgtcaaaata gcccagctcg aaatggagat gatcgccgaa
    24181 ggatactacg ggacaaaatg tattcgggag ataaacgaaa aatataaagt aaacatgccg
    24241 atcttggata ctttatatag tattctatac gaaaagaaat cgccgactac cgcgatacgg
    24301 cagttgactg aaacatttaa ataataatgt aaatatgaag aacatcagtc ttaacattga
    24361 caaagcgctg ggtaccgtaa cgaaagaaca ggtatatgct caggctgcaa aggcccacga
    24421 atgtaatgcc actttacaaa atggtaatgg tgcaggtaac gactttttag gttggttgca
    24481 cctcccctct tctattacag atgctgaact gacagacatc gaaaatacag ctaacgtact
    24541 tcgttccaaa tgtgaagttg ttgtcgccat cggtatcggc ggcagctatt taggaacaaa
    24601 agcagtggta gaagcattaa acaatagctt cgactggt
//
