LOCUS       c00063_gnlPro..        14852 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NLHAJIBF_63.
ACCESSION   c00063_gnlPro..
VERSION     c00063_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:46:07
            Original ID  :: gnl|Prokka|NLHAJIBF_63
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 148672
            Orig. end    :: 163524
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14852
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[158672:162112]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13440
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14852
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14852
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(32..1585)
                     /locus_tag="ctg63_123"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVSDLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
     CDS             complement(1619..3355)
                     /locus_tag="ctg63_124"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLSGISYFYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPI
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNQVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKAVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPGGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             complement(3376..3738)
                     /locus_tag="ctg63_125"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             4346..5236
                     /locus_tag="ctg63_126"
                     /transl_table=11
                     /translation="MLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYFRY
                     APDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDETID
                     RTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDVPL
                     EVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPWKQ
                     VMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPDVI
                     ETDYPYLFQGLDLTK"
     CDS             complement(5487..6602)
                     /locus_tag="ctg63_127"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATPVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(6599..7006)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_128"
                     /sec_met_domain="HBT (E-value: 2e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 3.1e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             complement(7006..8265)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_129"
                     /sec_met_domain="Peptidase_U32 (E-value: 1.4e-68, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             8646..9677
                     /locus_tag="ctg63_130"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             complement(9650..9808)
                     /locus_tag="ctg63_131"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_132"
                     /sec_met_domain="Fer2_3 (E-value: 1e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.2e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             complement(10784..12727)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_133"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.5e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.6e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(12766..13440)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_134"
                     /sec_met_domain="SucD_FumR (E-value: 1e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             13700..14653
                     /locus_tag="ctg63_135"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLKINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             complement(14762..14851)
                     /locus_tag="ctg63_136"
                     /transl_table=11
                     /translation="GSYALIDPGVGGGYMGGLGKFYYVFFIDF"
ORIGIN
        1 ttatatcgat tatattgttc agatattcta tctattccaa gtcggcgtct ttcaacattt
       61 tccgtgcttt ctctttttct tccttactca gggcaagcgt atcgagttta gcaccgcttt
      121 tacgcaattc cttttctttt tccctggctt ttttaatatg ttcctgcatc ttctcgcgcc
      181 tcagacgttc atcttccggc atttgcggta actgggcgac caaggcacgc agatcggaga
      241 cagccaactt tgtctttttc ccatcgggag ccaacatcgt cacttcgtcg gcattccgga
      301 aaaaggcatc ttcacaaacc gcttccaaga aagggcggta attataaaga tacttttgcg
      361 acttgtctgt cttcatatag gctgtcaggt aagtgtatct actgaaaatc gtcttttgca
      421 atttttcctc ctgctggaag agtcccggat cgacatccca gtattgtgta ctgatcttat
      481 acaggaagtg caactgggtt gggtcttcct tccatgcggc ataatacagc ttttccgctt
      541 cgggccaacg gccgtccctt tccaaggcat cacctcggaa ggtcgtcaac atattaacta
      601 ggaatttttt cggctgcata ttcgtttccg ccagatcgaa aagctcataa gcccgtttac
      661 ggtcgtatgt ttttcccagg gaagcgccat acaacatgac tgtttccaca tccgtcgaat
      721 ctatttcata ggccttctcc agcagctcga ccccatcaag tgcatgaccg gacatatagc
      781 gggccgcccc cgcatattta agattcaaaa aagaagaatc gccatcggcc aatagaccgg
      841 tatagactga atcagcctgc ttataatctt tcgtcatata gagagccatc cctttactct
      901 gccgtatctg gctgttatcc ggattataga acaaggcggt atcgcacacc tgcaaagctc
      961 cctgtccgtc ccccatccgc aataacgtat ttatcagaga agatgccaca cgcacatttt
     1021 ccgggttcag ctccaaagca cgggcataca aagaaagagc gatcatcgta ttaggaccgg
     1081 tccctctttt aatatggcaa tcagccagcc cggtcaggat agaaggattt tcaccttcga
     1141 tggaagcaag tatatgatag tgttccgtcg ctcgaccata atctcccaac tgataataga
     1201 gacgcgccaa ctgatagttg gcatagaagt tcatgctgtc ggttcccaat actttacgat
     1261 aacattgttt agcttccgct atccttccga aattgatcgc attcctggca acggcattca
     1321 atgcatccac attgttcgta tccatcttca agcaatgaga aaagcactga taggcctcct
     1381 tatagcgcaa cagtccttca tacgcctgcc cgattgccga cattgtagca taatcggctg
     1441 aatcggcagg agtaagacta tctgcacgtg ctacaacttc ctgaaattgt tttttattga
     1501 ccaattcctg aagattaaga ctctgcgcct gtccccaaag ggacagtacg caaagaaaca
     1561 gtaatagaga aaacttacat ttcataatgg tatcgtatta atgaccgatt ctggtcaatt
     1621 actgcaaacg gaaagtaacc ggaaccgtat attttacggc tacagccata ttgttttgta
     1681 cgccaggatt ccatttcggc atttcccgga tcacccggac agcctccctg tccagcgaag
     1741 gatcgattcc acggatcact tcaatatttt tcaaacttcc atccgtgtcg acaacgaaag
     1801 agcaagagac acgtccttgt attccattct cctgagcaat agccggatat tttatgcgtg
     1861 ttgccagata tttcaacaac gaagcctgtc cacccggaaa ttccggcatc tgttgcacta
     1921 ccgtaaagac acgaccggac gtatcgactt ctttaatctg cctctgcacg atacgagagg
     1981 atgttttttt ctttccaccg gaaagccgga aagttaccgg taccgtatat ttgacattaa
     2041 ccgctttgcc acgctgtttt cccggcgacc ataccggcat ggagtttatc acacgcaaag
     2101 cctcctcatt cagttccgga cttaccccac gaatcacttc tgcctccgag atagctccgt
     2161 cttttccaac aacgaaagaa cagctaaccc gtccctctat accattttta acggccgatt
     2221 ccgggtatct gacattcgtc gccaggaatt tcagcagagc accctgtccg ccagggaatt
     2281 ccggcattac ctccacaacg gtaaacacct ggttacgggc acgtctggca gcctcaattc
     2341 cttcctccga tagcacatac tcctcacgtt tttcagcagg agaagcatca ccgacaaaag
     2401 ggaacggcaa gatagcctcc ggtagtaaaa catcggcaaa cgtgctttcc gtcagttcgt
     2461 ccgtgatccg ggccaatgca tcgacattgc tcaaaatcag caaggcgccc acaatcggta
     2521 taaaaatcag gtatttcgtc ctccctatgc tccgggaacg tttcttattc atcatgctga
     2581 tccgattttt cagatgcagc atattaaagt tattagataa agaggtcacc gatctattgg
     2641 tatgtgccaa ccccaaaagg tgatattggt agctacgact gtcatagccc gattcaagta
     2701 ccgtatcatc cgccaaatat tccagattat gacgtacctc tcttttcaac agccagacaa
     2761 acggattcac ccaacagatg atacaaacca attcgcaaat aatcacgtca atcgaatgcc
     2821 actggctgac atgcgtacac tcgtgtacca aaatctcatc gatctctttc tcggaatggc
     2881 tgtcgggatg cagaaatacc agccggaaaa aagaaaaagg accggccggt ttattcaaca
     2941 gatgtacacg tacgttacgg atcaaagtca cttccgaccg ccgtgccagt aacaagatgc
     3001 tgctcaactg tactaaaaaa cggaacgata aggcaattac accgctccaa taaaaataag
     3061 aaataccgga aagtaacaaa tcatgccaat ttgtttgggg aacattgccg ggggttattg
     3121 tcgtttcagg caaaatggct gaatacattt gtatgacttc cactatcggc ccctgctccc
     3181 ggatccaatc ctgaatattc atcagcggat aaagcaatga caccccgaaa aatgccaaca
     3241 aaatggtacg gcgtagttta aagaaggtgt ccttataaaa gaacagccgg tagaaggcat
     3301 aaaggagtat aaaagctaca tttaccttca agaagtaggc aaattccggt gtcatggcat
     3361 tatgtattta acagtttatt ctcgtccttt ttcaatcata tcgataatct ctttcaactc
     3421 atcggtcgat atcttctgtt ccttagcaaa aaaggagacc atttccttat aagaattctc
     3481 gaaatagttg ttcaccacac ttcccataaa cgtccgttta tattcctcct gtgggatcag
     3541 cggcctgtat tcgtaagtat ttccgtaacg tttcgctttc acgtatttct tacgttccag
     3601 attcttcaca atagaagcga gtgtcgtata aggaggctta ggctcttcat acttcgccag
     3661 gatgtctttg ataaaacacg gctcgatctg ccagatccag cgcattacat cctcttcctg
     3721 tcttgttaat ctttccatgt ttctatatta ttttttacga tcgtatcgca aatctacgaa
     3781 tacatcgtaa atatgcaaga aataatgcgt taatttgtat taacaattaa taatccatca
     3841 tctattcgct gcatgcgcca aaaaggaatt tatctataag cagccacacc aaaacatccc
     3901 ctatattaat taatgatttt atatactcca aggggacact ttttaagcat gggatttcac
     3961 tttttccgac gataaaaagt atttgaatta gcagttttta catggaatct gtatagttta
     4021 taaataacca acattttttg acaaaatagc tattagagct taacatatat tatccgtaaa
     4081 aggcttgaca aacaagctta gctagtgtat ttttgcattg tggttttttc ataatagtat
     4141 tagatttaag gttaacaaag ttggttaggg gttgtcgaga tgacaatcct taatttttta
     4201 tatacctgcc tctttctttg cacatcttgt tgcctgtcat attttcatgt ttttatagtg
     4261 cttttatagt acgccactga taaaaaagtc ttacttttaa gccgcataat tgacaaagaa
     4321 tctatataaa tacaatatca tgaaaatgct atcttttatt ttggtactcc ttttaggggg
     4381 ttttatgccg gccgggaatc ttttggcttc agacaaagaa caaaatcctc attacattac
     4441 tgtgaagaac agccgggatc tacaagccta tttccggtat gctcccgatc gcccgattgt
     4501 aatcagtgga catcgtggtg gaatgctaga cggctatccg gagaactgca tcgaatcatt
     4561 cgaaaagacc ttgtcctata tggaatcgtt tttcgagata gatccgcgtt tgacaaaaga
     4621 cgggataatc gtattgatgc acgacgaaac catcgaccgg acaactaccg ggaaaggaaa
     4681 ggtttcagat tacacttatg cagaactgca acaattcaat ctggtggacc gaaacggcaa
     4741 cgtgacagcc ttcaaaattc caactttaaa agaatgcctg gaatggagca aaggcaaaac
     4801 aatcctgaat ttggatatca aggatgtacc tttagaagtt atggctgatt ttatagaaac
     4861 agaaaagcct gttaacgtca tgtacacggt acataacgcc agtcaagccc gctattatct
     4921 cgaccggaaa ccggatgcga tgttttcttg ctggtgtaag aatcgggaag aattcgataa
     4981 ttatgaaaaa gccggcatcc cctggaaaca ggtaatggct tatgtaggcc cgaagatgaa
     5041 gcctgaacag caaccactgt atgacgctct gcaccgtaac ggagtcatgt gcatgatttc
     5101 cgttgctccg acacatgatc gcgcgaaaac ggaaacagag aaaaccgccg gttaccggtc
     5161 agagatcagc actcgtcccg acgtgatcga aacggactat ccgtacctgt ttcaaggact
     5221 cgatttaaca aaataacgca gtttaaagga ttctttatag ccgattaaaa tctttttgct
     5281 atttatgctc atctgattaa caagtattag cgacaaaatg cttgacaaac gctcttgacg
     5341 agtgtatctt tgcaatgtgg ttttttcata atagtattag atttaaggtt aacaaagttg
     5401 gttaggggtt gtcgtgagac agcctttaat tgtttataga ggttccgttt cttctcccac
     5461 atacaaatcg tatacgaaaa agccggtcag gacagcttat agagatttcc cggcaacgct
     5521 tttaccttcc cgtttatttc cagttcgaac aatagcatag agagttgatg taccggtatc
     5581 tccaacactg aggcaagctc gttgatatgg atctcattcc gcgttcgcat aatggctaaa
     5641 accggatttt gttccgaggt gaatgtttcc gcctcggcga aaaacaactc cgtttgaacg
     5701 ggagtagccc cagcttggat atcccaacaa agagcggaga gcagatcgtc cgcagaagtg
     5761 atcaggccgg ctttattttg tcggatcaaa ttgttgcatc ctttggaatg gctgtcaccg
     5821 acacgccctg gaaagctata gacatcccgg ccataagaga atgcaatatc ggcagttacc
     5881 aaagagcctc ctttttctgc cgattcaacc acgatcgtac aatccgagat tccggcgaca
     5941 atccggttcc tccggaggaa atttggacgg tctggttctg taccgctggg aaaatcggtc
     6001 aacagaccgc ccgattccag catttcgaca gccgtattcc gatggcagga aggatagata
     6061 cgatccaagc catgcgccag cacagcaaca gtcggaagtc ggttgtacaa agcgttccgg
     6121 tgggcacaga tatcgatgcc gtaagccaat ccactcacga ccaacaagtc cgggatcact
     6181 tttgccaagt cttttataag ggattcggta agctctcgac catattcggt cgcgttgcga
     6241 gtacccacaa tactgatgat acgggtcgca tcaaggttag tatttccctt aaaatagaaa
     6301 agtatagggg catccggaca ttctctcaag cgcaccggat aatctgtatc agtcagataa
     6361 taacaggaaa tattgttttt ctcgataaaa gccaactctt tttccgcccg ttgcaagatt
     6421 tccgggcgtt tgatttcggc agcaatattg ctgccgatac cagggatcct tcctaacaac
     6481 tgttgctttt cagtaaacac agcctctgct tctcccaaag cctgcaggag atgacgcgcc
     6541 aggatatctc ccacgccgtt tatcatagta aggccgattt ggtaaatccg tttgtcagtc
     6601 atgtatgttc tattcttttt agcatttcgt cgaaatattc accgcgtgtc aactttccgt
     6661 tctcaacgat aaccgactcg acgattcctt tcgtcgccaa tgcattgtca gaagccctat
     6721 atatatcctg ctcgaatacg agcttgactc cttttttata gacattgagg caagagatat
     6781 agctgtcgcc gctcttgagc gaggtcttat actggatttc tacccgcgat acaaatccgt
     6841 caaccccttt ttcgtgcatc tttccgaagt tctcgccaag cgactccaag aattcatgcc
     6901 gagtatgttc catataatgc tgataattgg agttgttgac cactccttgc aggtcgcatt
     6961 cgtagtcacg gaccttgtct gtcagtttaa aaatatactc tttcattatt caaatacctt
     7021 ttcaagttga accttttcca ttttatacaa tcggtcagac ggccgaatct tctcgttcac
     7081 cttgagagag aaccgttcac ctttaacggt ctcgtccacc ggcttcaagt ccacacggat
     7141 ttcttctatc gtctgcataa ccgcacccgt tgtcggtccg gtaatcagga tctcatcacc
     7201 cactttcagg ttaccggatt ccatttcgaa ctccgccacg ccgatcttgt cgaaatattt
     7261 gattcctttg gcaacataca ctttcttctt agtcgcgccg gagccatatt tgctactcca
     7321 ctcacccaac cgttgcccca aataatagcc gtcccagaat cctcggttga acacactgcg
     7381 caggcgttcg tcccaagcgg caactttctt ttcatcgaac gtgccattgc aataagcacg
     7441 cacagcttcc ttatagcatt cggtcaccag gcggacatat tcgggaccgc gggcacgtcc
     7501 ttcgatcttg aatacccgta cacctgcatc catcatctta ttcatgaaat gaattgtctt
     7561 aaggtcttta ggcgacataa tatactggtt ttcgatatcc agttcgatat tgctgtcttt
     7621 atcttttacc gaataagcac gccgacaaat ctgcatgcaa gctccccggt tggcggaagc
     7681 gttcatttcg tgcaggctca ggtaacattt accggaaacg gccatacaga gagctccgtg
     7741 ggcaaacatt tcgatacgga tcagttctcc tttcggtccc gtaatctgct ggtcgacgat
     7801 ctgccgatag atttcatgca cctgtttcaa attcagctca cgcgccaaga cgacaacatc
     7861 agcaaaacgg gcatagaatt tcagtgcttc cgcattggaa atgttgagct gtgtggaaag
     7921 atgcacctcc tgtccgatgc tgttggcata gttcatagct gccacatcgg ccgcaatgat
     7981 cgctgaaact tccgcctcct tcgccgcatc gataatctcg cgcatcagag gcaggtcttc
     8041 cccataaata accgtattga cggtcaaata gctcttaata ccgtgctcac gacaaagcgc
     8101 aacgatcttg cgcaaatcgt ctgtcgtaaa gttattggaa gagcgcgaac gcatattcaa
     8161 tccttcgata ccgaaataga tagaatcggc tcccccttgg atagccgcca tcagtgattc
     8221 gtacgaaccg acaggcgcca ttatttcaaa atctttctcg ttcaagttct tatacattta
     8281 ctggttcgtt cgcaaaggta ggaataatat ccgagaagaa ttgcatgggt atccgtttct
     8341 cagagcatca aaatcgtgat caaataccat tttctataaa gatttgcaaa acaaccatca
     8401 tactgtcatt gttgtccttt agaatctgtt attcaatacc ttaagacatg atagtttcta
     8461 tttttaacta tcatactact atcatgcaac tatcatgatt tcagcttatc attttatcta
     8521 tatcattgac agtatgacat ttgtactttc tattgatcaa ttactacact ttttagtaga
     8581 tatcctttta tccctgtttt tagcaggaaa tcagtacctt tgtccccgtc attgataata
     8641 taaatatgaa aataggtaca atagatttag gcgaacgccc cgtcttctta gctccgatgg
     8701 aagacgttac agatatttct ttccggttga tgtgcaaacg ttttggtgcc gatatggttt
     8761 ataccgaatt cgtttcagca gacgccctga tccgcagtgt aaataaaaca cagcaaaagc
     8821 tgaatgtggc ggatgaagaa cgtccggtcg ccatacaaat atatggccgt gatgttccga
     8881 caatggtcga agccgcgcaa atttgcgaag ccgctcatcc ggacattctc gatatcaatt
     8941 tcggttgccc tgtcaaacga gtggcaggca aaggagcagg cgccggcatg ctgcgcaata
     9001 ttccactgat gctggacatc acccgtgaag tcgtcaaagc ggtgaacatc cctgtcaccg
     9061 taaaaacccg cttgggctgg gatgccgaca accggatcat cgtagacttg gccgaacagc
     9121 tacaggattg cggtatcgca gccctttcca tccacggacg tacccgggca cagatgtaca
     9181 caggagaggc agactggaca ctgatcggtg aagtaaaaaa caatccccgc atacaaattc
     9241 ccatcatcgg caatggcgat gtgacttccg ccgaaatctg caaacaacgt ttcgaacaat
     9301 atggcgtgga tgccgttatg attggccggg gcagcatagg ccgcccctgg attttcagag
     9361 aagtgaggca ttatctggat acaggcgaga cattgcctgc cgaatctttt tcatggtatc
     9421 tggacatact gaaaaagcag gtggaacaaa gcgtggaacg tttggatgag cgccggggaa
     9481 ttctccacat tcgccgccat ttggctgcaa ctccgctgtt taaaggtatt gcagacttca
     9541 agcagacacg cgtcgccatg ctacgtgcgg aaacagtgga agcattattc gacattctgg
     9601 attccatccc cgacaaattt catacaggat acggatttca aagcgactct caagtgtcag
     9661 aatcgatcga ttgttgatat aataacagtg tgaatccgca cacagtgtca attttaaaac
     9721 aaaaagtagc aaatttgcaa taaaatgtaa ttacaaactc ttgcgtattc agtaaatata
     9781 ctttatattt gcagtgagtt tttttcatag tattttagat ctaaggttaa caaagtcttt
     9841 gcagagaggg aatcgagaga ctgtttcact ggaaagcaac aaaaaagccg catccacttt
     9901 tattataggg agtgcggctt ttttgtgggt ttgaacgaac ataaagaaag cccgttgcca
     9961 ttggcaacgg gcttttccat atacatacat atataatgta ttagtcttgt aacttagcag
    10021 agatgaactc gcggttcaag cgagcgatgt tgctaacgga gatgttcttc ggacattcca
    10081 tttcgcaagc gcgagtgttc gtacagttac caaagcccag ttcatccatc ttagcaacca
    10141 ttgcttttgc acggcgagca gcttccacct taccctgagg caaaagagcc agctggctaa
    10201 cctttgcaga gacgaacagc atagctgaac cgttcttaca agcagcagca caagcaccgc
    10261 agccgataca agcagcagca tccatagcca aatccgcatc agccttagaa ataggaattg
    10321 cattagcatc aggaacccca cctgtgttta cagaaacgaa accacctgcc tggataatct
    10381 tatcataagc ataacggtct accatcaagt cgcggattac cgggaaacca gcagaacgcc
    10441 acggctcgat cgtaatcgtc tcaccatcat tgaaacggcg catatagagc tgacaggttg
    10501 ttgcacctgt tgccggtccg tgcggatgtc cgtttacata caatgaacac ataccgcaga
    10561 taccttcacg gcagtcgtgg tcgaatacga taggttcttt accttcgcta accaaacgtt
    10621 cattcaaaat gtctaacatt tccaagaaag aaacactctg attgattttg tcgatttggt
    10681 aagtctcaaa ctgtccttta tctttcggac ctttctgacg ccaaacttta agtgttacct
    10741 ttatatcttt atccatgatt ctaatttttg tgattgatga ttattacttc ttgtagttac
    10801 gtgtttgagg aacaacgaac tgatagttca aatcttcctt cagcataacc gggtctttgt
    10861 cttcaccctg gtattcccaa caagagacgt acatgaactt atcgtcatga cgcatagctt
    10921 cgccttcttc ggtctgatgt tccgtacgga agtggccacc acaagattct gcgcggtcta
    10981 acgcatcgtg tgccatcaat gcaccgattt cgataaagtc agccaaacgc aatgccttgt
    11041 ccaattccac gttcaagctg ttcgcttcac ccggaatgaa tacattgctc cagaattcct
    11101 tcttcaggtc tttcaacatt tggatagctt ctttcaagcc ttccgcgtcg cgtgccatac
    11161 cgacgtgttc ccacatgata tgtcccagct tacggtggat agaatcgact gtttctttac
    11221 ccttcacgtt catcaacttc gcgatacggg cgttaatagc cttttctgct tccacaaatt
    11281 caggcaggtc agtgctgaag cgcggaacct ggatctggtc agacagatag ttctggatcg
    11341 tgtaaggcaa tacaaagtaa ccatcagcca atccctgcat caaagcagaa gcacccagac
    11401 ggttagcgcc gtggtcagag aagttggctt caccgattgc gaacagcccc ggaatagaag
    11461 tcatcaattc atagtctacc cacaaaccac ccattgagta gtgcaatgca ggataaatca
    11521 tcatcggagt ttcgtacgga tcatcgttcg tgatctcttc gtacatatcg aacaggttac
    11581 catatttctg tttaaccact tccttaccca gacggttgat agcatcggag aaatccagga
    11641 atacagccaa gcccgtgcta tttacaccga aaccggcatc acaacgttct ttagcggcac
    11701 gtgaagccac gtcacgagga accaagttac cgaatgccgg ataacgacgt tccagatagt
    11761 agtcgcgatc tgcttcagga atatcctttc ccttttttgt tccggcctgc aatgccttcg
    11821 catcttccag tttcttcgga acccagatac ggccgtcgtt acgcagtgat tctgacatca
    11881 aagtcagctt agactggaag tcacctttca caggcacaca agtcgggtgg atctgcacca
    11941 tacaaggatt agcaaagtaa gcccctttct tgtagcactg ccatgcagca gaaccgttag
    12001 acgccatcgc gttagtagac aagaagaatg tatttacata accacctgtc gcaacaacga
    12061 ctgcgtgagc ggcaaaacgt tcaatcttac cggtaatcaa attacgggca ataataccgc
    12121 gagcacgtcc gtcaaccttc acaacatcca gcatttcatg gcgtgtgtac atcttcacct
    12181 ttcccaaacc aatctgacga ctcaatgcag agtaagcacc caacagcagc tgctgtccgg
    12241 tctgaccacg ggcatagaac gtacgggata cctgagcacc cccgaatgaa cggttatcca
    12301 acagaccacc atattcgcga gcgaatggta caccctgtgc tacgcactgg tcgataatag
    12361 agtttgacac ttcagccaga cgatagacgt ttgcttcgcg ggcacggtag tcaccacctt
    12421 tgattgtatc gtagaacaga cgataaaccg agtcaccatc attctgataa ttctttgccg
    12481 cattgatacc gccctgtgca gcgatagagt gtgcacgacg gggagagtcc tgaatacaga
    12541 aattcaatac attgaatccc atttcagcca gagaggcagc agcagaagca cccgccagac
    12601 cagtacctac tacaattatg tccaaacgac gtttgtttgc gggattcacc aatttctggt
    12661 gatttttata atttgtccac ttctcagcca acgggccttg aggaatttta gaatctattt
    12721 gagtcataat gttttatttt caaattgaaa aaataatatc cgaaattaag cacctacacc
    12781 gttcaggtag aagataactg tgataacagc gaataagcca caaataatag tggcaaccca
    12841 tttagagata cattcccaac ggcttaacca aacggtattg ttccagccaa ttgtgtgaat
    12901 cgcagaccag aaaccgtgag tcaggtgaaa ccacagagca acgaaccaga tcagatacaa
    12961 caccgtattc acaacattgc cctggaagta gaaattgata aacgctgcac catcctgcgg
    13021 atgaatgtca ccatgaatac ctgccagttc ggcaaacatc atgttgtacc agaactgagt
    13081 aaagtgcaga accatgaaca ggataacgat cacacccaaa acaaacatgt tctgagaagc
    13141 ccattcaaca cctttcggac gagcgttgat ggcataacgg tcgttaccgc gagccttacg
    13201 attctgcaga gtcaagataa tagcatacac gaagtgcacg actacacctg cagccaacac
    13261 caatgtaccg agcaaagcat accagttaga acccagcaaa ccgcaaatca cgttatacgc
    13321 ttcaccagaa aatactgccg caatgttcat acataagtgg aacaccaaga acagaatgag
    13381 aaaaagacct gatatactca ttatcagctt cttcccgata gaagaattaa gtaaccacat
    13441 aagataataa tttaagttat ttaattgtat ttagaaattt cctccaatct atggttatta
    13501 tcgtgcaaag gtatgctaaa tccccatatc acgcaaacga ttaaagaaat atttcatcaa
    13561 ttagaacgct gcttgctagc tggttttatt tgcatcagat atcacaaacg gattgtgcga
    13621 aatgaaaaaa tttcgttttt ttgtagccga tacaggcaag gtcttgccgg ataactgatt
    13681 attatttaat tgtcatatta tgaaaactgc tattttttct attggtgttt ttttgatttc
    13741 tctgttctta ggctcttgtc agccttccga aacatcctgt tccgtcgtcg acacggggaa
    13801 aaccttagac tataagatag gagataaact gttgttctct tacaactata ccacggttta
    13861 cccagcccct ggcgttgact cggtctataa acgcagcggt ttcatccatc ctttgaagac
    13921 attgggaggc gaagtgatga ccaattgttc tcccgccgac cattaccatc atttcggttt
    13981 gtggtatgcc tggacgaaaa ctacgttcga aggaaacgag atcgatttct ggaatctcca
    14041 caaaaaacaa ggaacagttc gcttccgcaa cttcgaacac gtatccgaca acggttttgt
    14101 tgcgacactg gaccatgtgg tctaccccga ttctcccgca gaaaaagtag caatgaacga
    14161 acgcctgaag atcaacatcg ggacaacatc cttaccaggt tattacatcg actatcatac
    14221 cactatccgc ctcgccagcc ccagcccgat caccatggaa gcttaccgtt atggcggcat
    14281 atgcatccgt acgcgcgaag actggaacga tcagacagcc gaaatgctca cctcggaagg
    14341 cctttcccgc gacgaagctg acggttcgag agcccgttgg tgctactacc aagggaaagc
    14401 cggaaacgaa aaggcctgta tcctaatcgt tgcctcccct tccaacctga actatcctga
    14461 gcctttacgc gtatgggaca aaactgtcaa caagcctgcc ggtgacgtca tgtggaattt
    14521 ctcaccgacc aagcagaagg cattcacatt ggagcccggt aaagaactga gcctgtctta
    14581 ccgcatttat gtattggaca agaacatcaa cgctactacg gcagaagtgc tatccgattt
    14641 cgaacgtgat tgaatttcta ctaaaacaag ctgacaattt gcagggcaag gtaaacaaga
    14701 aaaggaaaaa gggcttgttc tcctatatca ttaaagacaa ggctctttta tgtaaataca
    14761 gctaaaaatc aatgaaaaac acgtaataaa acttacccaa cccccccatg tatccgcccc
    14821 cgacacccgg atctataaga gcgtaagatc cg
//
