LOCUS       c00009_gnlPro..        16373 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIKBLOAK_9.
ACCESSION   c00009_gnlPro..
VERSION     c00009_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:40:33
            Original ID  :: gnl|Prokka|KIKBLOAK_9
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16373
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16373
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2821:6373](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2822..6373
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16373
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16373
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(249..1448)
                     /locus_tag="ctg9_1"
                     /transl_table=11
                     /translation="MTKKALYIFNPEHDLALASGETNYMAPASARQMASELALLPMWYA
                     EEGSVVLAPSAYNLDYVKKIQELLGLSVDLMTEPELASERNLDIRPWGWDIAIRKRLLD
                     LGVEESELPSIEQLDKLRFCSHRSCAVGLLPQLQLGACFCGESFYLTFPEEWKSFVESH
                     DTCLLKAPLSGSGKGLNWCKGVYTPSISGWCSRIGNQQGGVIGEPLYNKVEDFAMEFRS
                     SGNGRFGFAGYSQFRTGGSGAYEGNLLISDAAIERNLLEYIPVEEIYKLRDRLEQELSL
                     RFGTIYNGYLGVDMMICRFPESPVYRIHPCVEINLRMNMGVVARHIYDHYIYPTSTGAF
                     QISYYPTEGTAWRAHKEMEEAYPLEIEQGRIKSGYLSLVPAHKKSSYRAWVFISKSVFL
                     "
     CDS             1611..2789
                     /locus_tag="ctg9_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     RELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             2822..6373
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_3"
                     /sec_met_domain="PFOR_II (E-value: 4.5e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.2e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 5.2e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.8e-11, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.9e-08, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00014, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 8.9e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNASPEAKEVLKAWIENMYDADKTKE
                     LAPQVKAVIEEGLSHGCPICKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAK
                     WRYNSYKRLARENWGAE"
     CDS             complement(6334..6483)
                     /locus_tag="ctg9_4"
                     /transl_table=11
                     /translation="MNSSGKKVVLFMLDRVHTIKNGNLLQDYRFLFIGYYYYSAPQFSL
                     AKRL"
     CDS             complement(6525..7397)
                     /locus_tag="ctg9_5"
                     /transl_table=11
                     /translation="MHVRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAM
                     SHLAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEF
                     LGEVYGEARVGLVVPQYVTIQSINELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGL
                     DGYTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEI
                     HAIAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVD
                     SWIPKSENK"
     CDS             complement(7415..8239)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 8.7e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg9_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.2e-28, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMVHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLATLAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(8236..9462)
                     /locus_tag="ctg9_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTAGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGD
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(9761..10099)
                     /locus_tag="ctg9_8"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             10183..11478
                     /locus_tag="ctg9_9"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPNKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKRITDLNIPADFDWKGSQNAKVKIASQSTATISVFLEEN
                     CNEEALMLRMDVDANISKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPA
                     NATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDG
                     FYWSHNQCYAEYLMIGFQIRAIGGIYDYNPYIRLAEVQYNELDLEETQMYLERNNPEEA
                     ENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQ
                     DSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFL
                     EAYPDFEQWVTSGGQKNQRWWNKPKTNKLIMN"
     CDS             complement(11620..14502)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 62; E-value: 2.1e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 2.7e-19, bitscore:
                     62.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYTKWITVLLCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLHRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKEMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDILEEQRD
                     KLEEQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQR
                     RMLLLVQRNVNILLRLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAAARKKH
                     IHFSFDYMPDTDYRTLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIR
                     FTVANTGSMISAEHIRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQG
                     TIFTVDLPVQTCETVVSENSPAFSVPATSVTSTDAATSAVAGAPVTPATSGYSGSSSLN
                     DALTYEEEELEKSYDSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAADGSEGIRKAMK
                     YVPDLIISDVMMPGMDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYI
                     SKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGD
                     SNLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGY
                     EVGFSSPSYFTKCYREQFGESPTDLLKRKG"
ORIGIN
        1 atctaaaatg acaacttata caggaattac aaagggacaa gtaaacttat ttaggtttta
       61 aaaaatattg agtaaactaa cttaggtata acaagcgaag ttgtcaacta aatccagtac
      121 agtacatcac atggcatgtg attacttgtt tcatgcaatg aaactttttg tttctcggtg
      181 tggaaccaat ggtttcactg catgaaacta tcagtttcac accgagaaac cataacttcg
      241 atataatatc acaaaaacac gctttttgag ataaacaccc acgcccgata actactcttt
      301 ttatgagccg gcaccaatga caaatagcct gattttattc ttccttgttc tatttccaaa
      361 ggataagcct cctccatttc tttgtgtgct ctccaggctg ttccttccgt agggtaatag
      421 cttatttgaa aagctcctgt tgaagtagga tagatataat ggtcataaat atgacgcgct
      481 actactccca tattcatcct caagttgatt tccacgcaag gatgaatccg ataaacagga
      541 gattctggaa agcgacagat catcatatcc actcccaaat aaccattata aatggttccg
      601 aaacggaggg ataattcttg ttcaaggcgg tcgcgcaatt tataaatttc ttcgacaggg
      661 atatattcca aaagattccg ttcgatggct gcatctgaaa tcagcagatt accttcgtac
      721 gccccacttc cacccgtacg gaattgagag tatccggcaa agccaaatcg accattaccc
      781 gaagaacgaa attccatagc aaaatcttcc accttattat atagaggttc gccaataaca
      841 cctccttgct ggttgccaat gcgtgagcac caaccggaaa tggaaggagt atatacacct
      901 ttgcaccaat tcaacccttt tccgctaccg gataaaggag ctttcagtaa acaagtatca
      961 tgtgattcta caaatgactt ccattcttcg ggaaacgtca ggtaaaaaga ctctccacaa
     1021 aaacaggctc ccagttgtag ctgtggtaat aatcccacag cgcaggaacg atgggaacag
     1081 aaacgcagtt tatccaattg ctcaatagaa ggaagctcgc tttcttccac tcccaaatcc
     1141 aacagtcgtt ttcttattgc tatatcccag ccccaaggac gaatatccaa attccgctcc
     1201 gaagcaagtt caggttctgt catcaaatca accgaaagtc ctaataattc ctgtatcttc
     1261 ttcacatagt cgagattata agcggaagga gccaatacaa cacttccctc ttctgcatac
     1321 cacatcggca acaaagccaa ttcggatgcc atctgccggg cggaagccgg tgccatatag
     1381 tttgtttcac cgctggctaa cgccaaatca tgttccggat tgaatatata aagagccttt
     1441 tttgtcattt taaacgaatt caaaacttta ttctgcaaat atatacagga aatagtcagg
     1501 aatggctaca ataaacagaa agttctaatt aaactcacaa ttttgccatc tctactttgc
     1561 aaatcctaaa aaaagcagta tatttgccac ccgaaaaaca aagaactgaa atggaatcat
     1621 tctatcgcac acacgcctac ctcgttgagc acaccaatgc ccccgttcgc cgcgatctta
     1681 tggacgagat cgactggagc gaccgcctga ttggtatcaa agggacacgt ggcgtaggaa
     1741 aaaccacttt ccttctccaa tacgccaaag aaaaatttgg gaacgaccgc tcctgcctgt
     1801 tcatcaacat gaacaacttc tacttctctg gccacagcat tgtagacttt gctaacgaat
     1861 tccagaaacg tggtggaaaa gtattgttga tcgaccaagt gttcaaacac ccggaatgga
     1921 gcagagagtt gcgcatgtgt tacgaccgtt ttcctaattt gaaaattgtc tttaccggct
     1981 catctgtaat gcgactgaaa gaggaaaatc ttgaattgcg tgatattgca aaaagctata
     2041 acctgcgcgg attttctttc cgcgaatacc tgaacttaca aacaggcatg aaattcaggg
     2101 cctacagtct cgaagaaatt cttagcactc acgaacagat tgccaaagga gtactctcta
     2161 aagttcgtcc gctggattac ttccaggatt acctgcatca tgggttctat ccattcttcc
     2221 tcgagaagcg taacttttcg gagaatttgc tgaaaacgat gaacatgatg gtggaagtag
     2281 atatcctgct catcaaacaa attgaactga aatatctttc aaagataaaa aaattactat
     2341 atttgctcgc tgtcgacgga ccgaaggctc ccaatgtgag tcaactggca agcgacatac
     2401 agacatctcg cgccacggtg atgaactata tcaagtatct ggcagatgcg cgactcatta
     2461 atctggttta tccgaaagga gaagaatttc ctaaaaaacc ttccaagata atgatgcaca
     2521 actccaacct gatgtattcc atctatcccg tgaaagtgga ggagcaggat gtactcgaca
     2581 cattctttgc aaattcttta tggaaagacc ataaggtaca taaaggagat aaaaacgtct
     2641 cttttatggt ggacgaagta atgccgttca aaatttgcca ggaaggagca aagatcaaga
     2701 acaatccgaa tgtgacgtac gcgttgcata aggctgaaat aggtcggggc aaccagatac
     2761 ctctctggat gttcggcttt ttatattaaa agatttattt acttaaatat ttaatttagt
     2821 tatgactaaa cagaagaaat tcatcacttg tgatggtaac caggctgcag cgcatatctc
     2881 gtatatgttc tctgaagtag ctgctatcta ccccatcact ccttcttcga ctatggctga
     2941 gtacgtagac gaatgggctg ccgcaggacg taagaacatc ttcggcgaaa cagtattggt
     3001 acaggaaatg caatctgaag gtggtgctgc cggtgcagtt cacggttctc ttcaggctgg
     3061 tgcgttgact actacttaca ctgcttctca ggggcttctc ctgatgatcc ctaatatgta
     3121 caaaattgcc ggtgagttct tgccttgcgt attccatgta tctgctcgta cattggcttc
     3181 tcacgcattg tgtatcttcg gtgaccacca agacgtaatg tcagctcgtc agactggctt
     3241 tgcgatgttg gctgaaggct ctgtacagga agttatggat ttggctggtg ttgctcactt
     3301 ggctaccatc aaatctcgcg ttccgttcat gaacttcttc gatggtttcc gtacatctca
     3361 cgaaatccag aagattgaaa tgttggaaaa tgatgatctt gctccgctga tcgatcagga
     3421 agctttggct gaattccgtg cccgcgcact gaatccgatg aatccggttg ctcgtggtat
     3481 ggctgaaaac cccgaccact tcttccaaca tcgtgaatca tgtaacaact actatgaagc
     3541 agttcctgct atcgtagaag aatacatgaa tgaaatttct aagattacag gtcgtaaata
     3601 cggtttgttc gattactatg gtgcagaaga tgcagaacgc gtaattatcg ctatgggttc
     3661 tgtaacagaa gctgcccgcg aagctatcga ccacttggta gcaaatggcg aaaaagtggg
     3721 tatggttgcc gtacacctgt atcgtccgtt ctctgctaaa cacttcctgg ctgctgtacc
     3781 taagactgcc aagactatcg cagttcttga ccgtactaaa gaaccgggcg ctaacggcga
     3841 acctctttac cttgacgtta aagactgctt ctacggcgca gaaaatgctc cggttatcgt
     3901 tggcggtcgc tacggtttgg gttcaaaaga tactactcct gctcaaattc tttcagtatt
     3961 cgaaaacttg gccatgccaa tgccgaagaa tcacttcact atcggtatcg tagacgacgt
     4021 tactttcact tctcttcctc aaaaagaaga aatcgcttta ggcggtgaag gaatgttcga
     4081 agctaaattc tacggtttgg gtgctgacgg tacagtaggt gctaacaaga actctgtaaa
     4141 gattatcggt gacaacactg acaaacactg ccaggcttac ttctcttatg actctaagaa
     4201 gtcaggtggt ttcacttgtt ctcacttgcg tttcggtgat actccgatcc gttccactta
     4261 tttggtaaat actccgaact tcgttgcttg tcacgttcag gcttacctgc acatgtacga
     4321 tgtaactcgt ggtttgcgta agaacggttc tttcttgctg aacactatct gggaaggtga
     4381 agaactggct aagaacctgc ctaacaaggt taagaaatat tttgcacaga acaacatttc
     4441 cgtatactat atcaacgcaa cacagattgc attggaaatt ggtttgggta atcgtaccaa
     4501 cactatcctt caatctgcat tcttccgtat cacaggtgtt attcctgtag accaggctgt
     4561 tgaacagatg aagaaattca tcgttaagtc ttacggtaag aagggtgaag acgttgttaa
     4621 caagaactat gctgccgttg accgtggtgg tgaatacaag actttagctg ttgatcctgc
     4681 ttgggctaac ctgccggatg atgcaaaagc tgaaaacaac gatcctgcat tcatcaacga
     4741 agtagttcgt ccgatcaatg cacaagatgg tgacttgctg cctgtatctg cattcaaggg
     4801 tatcgaagac ggtacttggt atcaaggtac ttctaaatac gaaaaacgtg gtgtagccgc
     4861 attcgttcct gaatggaatc cagaaaactg tatccagtgt aacaagtgtg catacgtttg
     4921 tcctcacgct tctatccgtc cgttcgtact cgatgctgaa gagcagaagg gtgctaagtt
     4981 cgaacaattg aaagcagtag gtaaagtatt cgacggtatg acattccgta tccaggttga
     5041 cgttctcgac tgtctgggtt gcggtaactg tgctgacatc tgtccgggta atccgaagaa
     5101 gggtggcaaa gcattgacaa tgaaacacct cgaaagccaa ttggctgaag ctgacaactg
     5161 gacttactgt gctgaaaacg tgaagactaa acaacatctt gttgatatca agtctaacgt
     5221 gaagaactca cagttcgcta ctccgttgtt tgagttctct ggtgcttgct ctggttgtgg
     5281 tgaaactccg tatgtgaaat tgatttctca attgttcggt gaccgtgaaa tggttgctaa
     5341 cgctaccgga tgttcttcta tctactctgg ttcagttcct tctactccgt atactacgaa
     5401 cgaaaacggt cacggtcctg cttgggctaa ctcactgttc gaagacttct gtgaattcgg
     5461 tttgggtatg gaattggcta atgaaaagat gcgtgctcgt atcgtgaagt tattcaacga
     5521 aatccttgct gccgacaacg cttcacctga agcaaaagaa gtgctgaaag catggattga
     5581 aaacatgtac gatgctgaca agactaaaga attggctcct caagtgaaag cagtgattga
     5641 agaaggtctt tctcacggat gtcctatttg caaagaactg aaaggactga ctcaatatct
     5701 tgtaaaacgc agccaatgga tcattggtgg tgacggtgct tcttacgata tcggttatgg
     5761 tggtcttgac catgtaatcg cttccggtaa ggacgttaac atcctcgttc tggatactga
     5821 agtttactct aacacaggtg gtcagtcttc taaggctact ccggtaggtg ctatcgctaa
     5881 gttcgctgct gctggtaagc gcgtacgtaa gaaagacctc ggtctgatgg ctactactta
     5941 cggttatgta tatgttgcac agatcgctat gggtgctgac caagctcaaa ctctgaaagc
     6001 tatccgtgaa gctgaagcat atccgggacc atctttgatt atcgcttacg ctccatgtat
     6061 caaccacggt ctgaaagcag gtatgggtaa gagccaggaa gaagaagaaa aggctgttaa
     6121 gtgcggttac tggcacttgt ggcgttacaa cccggctctg gaagaagaag gcaagaatcc
     6181 attccaattg gatagcaaag aaccgaactg ggaagatttc caaggtttct tgaaaggtga
     6241 agttcgttac gcttctgtaa tgaaacaata tcctgctgaa gctgaagaac tattcaaagc
     6301 tgccgaagaa aacgctaaat ggcgttacaa cagctacaaa cgtttggcta gagaaaactg
     6361 gggtgctgaa taatagtaat accctataaa taaaaaacgg taatcttgta gaagattacc
     6421 gttttttatt gtatgaactc tgtccaacat aaacagtact acctttttcc cactagagtt
     6481 catgtctatt ttatatttaa aattaagaat aacaatgctc caatctattt attctctgac
     6541 ttcggaatcc aactatccac caacagccga tgctcatccc tccatttacg ggctatttct
     6601 tcttcatcca tcctggcatc cttcatagct gtcataaaag agctaagttc ttctgtcgtt
     6661 agtttgatgt tgccaaagaa ctcggcagca aacggatctt tctcactgaa tcctttccat
     6721 gcaatagcat gtatttcttc caagtctcca tatactttct tcggatcatc caagaatttc
     6781 aagtcaaact ggtcgaacat ccaatgcggt gtccaccccg taatgacaat ccattctcct
     6841 ttgtccatcg cttttttcaa agaagccagc atggtggaac tacttgaagt catgagggta
     6901 tacccatcaa gtccgtaagc agcaatggcc ttatcggtcg tcttcattat ccctgctccc
     6961 gcatcaattc ctactatttc agaagaaaaa cggtctttat tagcttccag ctcattaata
     7021 gactggatcg taacatattg aggaacaacc agtccgacgc gagcttctcc gtatacctcc
     7081 cccaaaaatt cgatgctgtc tccatactga tccatataat ctttcatcgt tattggtaac
     7141 caggcatcca gaaacacatc tgatttcttt cctgacatag atacaaaaat aggggcaaga
     7201 tcagcatttt gcaattcaac ctcatatcca tgctcttcca ataccacctt agccaaatga
     7261 ctcatggcaa taccttccag ccaattggca taggctattt ttactttctt tttctctaag
     7321 tctgaattag tacaggaagc tagcaaaagc atagccgaaa gcactattcc tactatttta
     7381 tatattctca catgcatttt tattcctttc cgttttagtt cttatttttt cgtcctgcca
     7441 ttccttgtgt gatacggtct aagatgatag ctaaaataac aacagctata ccaccttcaa
     7501 acccaagtcc gattttcatt tgggtaatac ctttcaatac aatttctccc agaccaccgg
     7561 cagcaatcat ggcagcaatg acaaccatag aaagcgacat cataattgtc tggttgacac
     7621 ctgtcagaat ggtgggcaac gccaaaggaa gctgcacttt atacaataac tgccaacggg
     7681 tagccccgaa cgaacgggaa gcttccacta catttttagg aacttgccga attcccaatc
     7741 cggtaaggcg gactacagga ggcatagcaa agataatggt agcaaacact cccggcactg
     7801 ctcccaatcc gaaaaacaaa acagcaggaa tcagataaac aaaagcaggc atcgtctgca
     7861 tcaagtcgag aacaggacga agtattttct ctgcacgcgg actgtttgcc gtccacactc
     7921 ctaaaggtac accaacaatc agagccagac aggtagatga aaaaacgaga gccagggttt
     7981 gcatagtagc ctcccagaat cccattccat agatcagtaa taatcccaat gcggtgaaaa
     8041 ttgccgtacc gcgtcctgct ttcatccatg cgagtgtagc aagtaccaaa atggttatat
     8101 aaaaaggtat tccgaaaagt atgtgttgga atcctataat aaaactaccg atgcccgcat
     8161 tcacggcatc aaagaaagtg gaaaaatgta ccatcatcca attgatggcc atctctatat
     8221 attgtcctat atttatcata aatctattgc gttttgaatt atttcgttta tttcttcttt
     8281 gtctttcccg gtcacttcga tgattaagga tgaaagcggg attgttccta aaaactcgcg
     8341 cgtctcatca atcacccata ccggcgaatt gctctttgtc attagaggaa gtatatcctc
     8401 caacaccgta tcctccaaca cagaatgtac ttctgtacgc acaatcgttt caatggattt
     8461 ttcctgtttg ctacgtaact taagcaagtc gttcagacgt acttctccga ccagtttatc
     8521 atcggcgtct atgacaggta atacggtgat attcttcgca cgcatcttac gaatcaatac
     8581 ttcgggacct tctttcttca gacgggccac caacggtttg tcaatcatta aagaagaggc
     8641 ggtaataatt ttgctcctat ccacgttttc aacaaaacgg gctacataat cgttagccgg
     8701 ttcagtcagg atttcctccg aagtacctac ctgcaccact tctccgtctt tcatgatggc
     8761 aatacggtca cctagcttaa ttgcttcact caagtcgtgg gtaataaaaa caatcgtctt
     8821 tttcatcttt gattgcaagg ccagtagttc atcctgcatc tgtacgcgaa tcagaggatc
     8881 gagagcagag aaagcctcat ccattaaaag cacttcagga ttattagcca gagcacgagc
     8941 cagtccgaca cgctgttgca ttccaccgga aagatcgcct accatctgat tttcatatcc
     9001 tttcaatccg acaagcttca tgctttccat cgctttcttc tcacgttcct ctttcttcac
     9061 tccctgaagt tcgaggccga acgcgatatt gctcaatacg gaacggtgag gtaacagacc
     9121 gaaattctgg aaaaccatcg ccagctcttt ccggcgaacc tgcaataatt ctttttcgga
     9181 aattttagat atatctactc cgtttacaag cacttgtccg gcagtaggac gtatcagacg
     9241 attgatacaa cgcagtaatg tcgattttcc acttcccgag agtcccatta tcacgaaaaa
     9301 ctctccttca ttaattgaaa gattggcatc tttcactcct accgtacaac cggtatcttt
     9361 cagaatttcc tctttactct tatctttttt caacatcttg agggctttct gcttctcgtt
     9421 accaaagata aggtacaaat cctttatttc tattttactc atataatata ttggtttaga
     9481 ttataatatt tgttttgttt tcaactgccg cattccttat tctcacttac gataaacaag
     9541 ttgaatgttc gcatggttca gtcatgccac atgataacat gacggtccga cgttttttaa
     9601 atggttaaaa aaaacagaca gagtagttta aaaggaatag aatttgataa gattatcctc
     9661 ttaatgaaca gtagaaaata gtattttcat aaataaataa cagtctgttc ttgcatattg
     9721 ttggcacaaa ggtaaggaaa atagattaaa tatgcaaatt tcattcaggt acggagtaat
     9781 tccaaagatg ctttttcaag tctacgcatc cattttgttt gaaagagatc ccttcttcca
     9841 acaagagttg tttctgctct gtccaacccg gaacaagccg tcccgacgca ttgacaaccc
     9901 gatgacaagg cgcagataaa tcatccggaa tctgtttcaa agcacgcccc accatacggg
     9961 aacattgaga cattcccaat aatgcggcaa ttcccccata ggtagaaact ttacctaccg
    10021 gaatttctcg gacaacctga tacacctctt gacaaaagga tgcggaaagg ctcgccttat
    10081 ctactttata atctttcatc actcaaacat tactttattt cagttccaaa actagataaa
    10141 aagaaaagaa tttgcaaata ataaaagcat ttcaaataaa atatgcaact ttatttgctt
    10201 tatttacaaa taatcccgac ctttgtcccc aataaaagca accctattat taacaaaaca
    10261 agcactgctg ttatgaaaaa gaaaactatc ctgttcgctt cttgtttatt gggagcactg
    10321 gctttcagct cctgtgagaa gaacctttat gatgaaagta aacaacccga gaaagaaaag
    10381 agaataacag acttgaatat tcctgctgac tttgattgga aaggttctca aaatgccaaa
    10441 gtgaaaattg ccagtcaatc aactgctact atttctgtat ttctagaaga aaattgcaat
    10501 gaagaggctt tgatgcttcg aatggatgtc gatgccaaca tatcaaaatt ggaactccca
    10561 attgaaattc ctgcatatat aaaaaatgtg tatgtaaaat atggtaatgg ctctgaaata
    10621 caaactgttc ctgttgaaag taatggtact atttctatag tagtacctgc taacgctacg
    10681 gcattatcca gagttaccac aagagctaat aaagaagttg aaacgaacaa catcttcaat
    10741 tatccgggat atggcaacgg aactattatg ttcgaagata tgtatccagc tttaggcgat
    10801 tatgatttta atgattttgt tgcatggtat aatttccaaa ttgacggttt ttattggagt
    10861 cacaatcaat gttatgcaga atacttaatg ataggattcc aaatcagagc tataggaggt
    10921 atatatgact acaatcctta tatccgcttg gcagaagtac aatataatga acttgattta
    10981 gaagaaactc aaatgtatct tgagcgtaac aatcctgaag aggctgaaaa tatcaaaatc
    11041 ctaaaaggcc caaaagggga attgattatt tcactaaaga aaccggccat tcctaacgga
    11101 tacaagtatt ataatacgga ggtaaatgaa aaaacaaagc ctaaaaaaat gatggccatt
    11161 tacttggtgt tcaactcacc tgttaacgtt aaaagcctac aagacagtaa aatggacttt
    11221 tatattgcaa aaactaataa aggacaagaa atccacttaa aaggttatag cccggtttat
    11281 tataacagca acgaaagtta tgtaaatgaa gacaacttta tatggggatt aaaagtacct
    11341 gcatctttac atcatgccag agaagaagta aacttcttgg aagcatatcc agactttgaa
    11401 caatgggtaa catcgggagg tcaaaagaac caaagatggt ggaataagcc aaaaacgaat
    11461 aagttgatta tgaattaata aatatacagt aaatcatata ctgaattaaa taagaggtaa
    11521 ggtatgtcaa tagatttcct tacctcttat ttttatcata tgaattccat agaagtataa
    11581 acagataaat gctcaccatc aaattttgca gattctatcc tatcctttcc tcttcaacaa
    11641 atctgtcgga ctctctccaa actgttctct ataacattta gtaaaataag aaggagaact
    11701 aaaaccaact tcataaccta tctctgccac tgtcatatcc gacgaggcaa gcagagaagc
    11761 agctttcttc aaacgagcta tacgaagcag ttcattcgga gaataattag tcagagattt
    11821 aatcttgcgg taaagttgca cacgacttaa tcccatatcc ttacccaaat cttctacatt
    11881 caaatttgaa tctcccatct ttgcctcaat cagagctttg aatttttcca caaagtcttt
    11941 atccatatca cagacatcct ctttcgccaa cgtttgtccg tcaccaaaaa actgtttcag
    12001 gcggcggtgt gaatctatca gattacgaac gcgtgccaat agtaattgcg aactgaaagg
    12061 cttggagata taagaatctg caccaccatc atacccttga attcgttgtt catccaaaga
    12121 acaagctgtc aataggataa caggaatatg acaggtttgt aattcgcttt tcaagcgacg
    12181 acaacattca attccatcca ttccgggcat cattacatcg gagataatca agtccgggac
    12241 atatttcata gctttacgaa taccttccga gccgtctgca gcttctataa cagtataatc
    12301 agtgtgaagc aatccatgca catataagcg aatatcagcg ttatcatcaa taatcagaac
    12361 gcaaggtttg gaagagtcgt aacttttttc caattcctct tcttcgtaag ttaaagcatc
    12421 attcaagctc gaagaaccgg aataaccaga agttgcagga gttacgggag ccccagcaac
    12481 ggcagaggtt gcagcatcgg tggaggttac agaagtagca gggacagaga atgccggaga
    12541 gttttcagaa acaacagtct cgcaagtctg tacaggcaaa tcaacggtaa agatagttcc
    12601 ttgcttttca tcactttcca ctgtgatggt acctttatgc aattccacaa aagcctttac
    12661 caatgccagt ccaatacccg aaccggcatg gtgcatatct atcttataga aacggtcgaa
    12721 aatattccgg atatgctccg cagaaatcat tgagccggta ttggcaacag taaagcgaat
    12781 ccaacaatga tcgtctttag tcagggaaga taagcgtaca gttacttttc cattctccgg
    12841 agtaaatttg aaagcgttgg aaaggaggtt gaaatagatg cgttccaact tttctacatc
    12901 tgccaatgtg cggtaatccg tatccggcat ataatcgaat gagaaatgaa tatgtttctt
    12961 ccgggctgct gccatgaaag actcgttcca tccctcaaaa gaagaaagaa tgtctaacga
    13021 aataggagta tattccattt ttccattctc gtatttacga aaatccagaa tctgattgac
    13081 aagacgcaag aggatattca cgtttcgctg aactaacaat aacattcggc gctgatcttc
    13141 actcaaagac gaatcagcca gtaaatgctc taccgggtcg gcaactaatg tcagtggagt
    13201 acgaaaatcg tgagatatat ttgtgaagaa aaccagcttg gcatgagtcg cttcttccag
    13261 ttgatgagaa agctggataa gctgatcccg ctgttcttcg agtttgtcac gctgttcttc
    13321 aagaatatcc cgttgctctt cgagtttatc gcgctgttgc tctacttgtt tcttctgttc
    13381 ggacaactct ttattcaggc gattcttgga acggagggat ttatagacta ccaacaacaa
    13441 tcccgctact aataaaagaa taaccaagcc gccatacatc acgacctgct gcgtagctac
    13501 acgcgacaga tacccaccga tacgtccgtt caatgtttca atcttctgat ccagttccga
    13561 gatatgggta gtctgaagtt gcataacgtg cgcgttcgtg cggtctacaa cggcagtatt
    13621 catgaccgtt tcgcgaggat aagacttctt ctcaagaata ttcatggcca gttgcatcac
    13681 tttgtcccca ttagtcggat aaataaaagt tgcatcgagc acattgtcaa gcaccaattc
    13741 aagcccgttt cctttgccgg gcagggcatc aatgccaaca aaaatcattt ccttttcacg
    13801 tccggctttc ttcgcagcct gataggctcc cggagcgata cggtcgttat gtgcatacac
    13861 cgcatcaatc ttcggatgac ggtgaagcat actatccatt tccacttctg ccggttcacg
    13921 ttcccaggca gcatccgctt tatcaatcag tttgatatcc ggataattgc tgatagcggc
    13981 cataaatccc tgatggcgct ccatagcagg ggtggaacca cccagtccgg taagctccac
    14041 tacattccct ttccctttca gacttgatgc gatataattt cctaccgcac gacctatttc
    14101 ataattatcg gcaccaatat aggcagtata tttatcagaa agtatcttcc ggtctacaag
    14161 aatgacaggt attcctttct gataggcctc ctccacaatt ggagtcatgg gagccgcttc
    14221 attggcggaa attatcagta aatcaactcc tttatctata aaataatgaa catcttccgc
    14281 ctgcttacgg ttatcatccg ccgccgaacg gatttcaacc gacactccat cataaaacat
    14341 cgcttcgcga agaatctcat cattcatctt gtgcctccaa gagtcatcgc tacattgggc
    14401 caccccaata cggaaacgag gcgcatcctg ccgacaggcc gccaagccca aaagacaaag
    14461 caagactgtt atccacttcg tatatttcat cgcttcaatc attccctttc tttcgtatat
    14521 cttttgtatt tctttctgta atccaaattt ctctccccgc attatttgca ttcaccaccg
    14581 ggaaatacat cagttccact ttcacagggt tcagcgtata ttttccagta aagcgtggaa
    14641 gcaaaggaac cgtaaactga taagtaccta ccggtaattt ttcgctaaag ataacagttt
    14701 tctctttaaa atactcacga tatacttcag aacgggagaa attaacaggt tttgaggcat
    14761 aactacaacc tgccggaaca ggaacttcga gcatcacata ttgcgcaccc tcctgtttca
    14821 cctgcaaggt aactgtcaat gtaacaggta cacccgccac caaagagtct ttttccaaag
    14881 tcacctccac cttgaaagca tcactctgac gagcattcat cacacgcttc attgaataga
    14941 cactatacaa taaaggctct tttcccgttt ttgaaataag cagactgtcg cctgctgtca
    15001 gccgggcatg ataaggaaat tccgtaattc gttgatgatc cttaccgctc acagacaccg
    15061 acgttcctga catccctccg gaacctgcca gcaaatcggt cagaacagtt gccacagccg
    15121 aagaagcctg atacgtattc catccgcgct ccttagtccg caaaatatac aattgcatat
    15181 tttctttcaa cttacacagg gaagggtcat ttttaataat ccggtaggct atcaatgtat
    15241 ttatcatctg atttccctcc caataataag tacgccgtcc gtcgtcacag taaacacctt
    15301 ccagcatatc ctttttcaga taaggacgta cgctatcacc cacattcacc gaatccacct
    15361 gttgcttgat ttcccagaga agcagcttct ctttcaagta tgaaagagga cgataatact
    15421 tgtttctatt tgccaacgag tcttctttct gttccaattg ccggacgaaa ggttccaata
    15481 atctgactgc cgaagaataa tccgcctcta ctttccactc atgcagagca tgaagtattt
    15541 ctatatcttc cagtttcatt cctcgataag gacgcgtatg agcatactcc actttcaaac
    15601 cattcagatt caactccaca ggataacctg catcttgcgc catcttcaaa gcccgcagaa
    15661 tatgcgcaga catccagaaa gaagtatttt cagagttccc ccaccacgac cataactgat
    15721 gtttgttctg atgattcgtc agtcgatgga tgataggtcg aattgcttta tctactttca
    15781 ccttttcacc cttactctgc atatactgtt ggtaagccaa caaaccggtt aacttggatg
    15841 ccagctgctc attgcacaaa tatttgtatc ctgtcaagta attcactgat tctttataga
    15901 tgtccaactg attgtcagtg atactcacca tcacttcttc atcctcgccg gattgcactt
    15961 tgaccgtctt tgcatcggac agaataccca atgtgccctc cgccaattca gttccctgtg
    16021 gcagtatcgg aatcgtatat tcctctccat cctgatagcc atcgtcgcga gtgaaaagat
    16081 agctgatggt cacgctatcg gcatgaactg cctgcatcgg cactgtttca tgaaatccct
    16141 ccatgaaact cacttcctgc cgtttcaacg tatccgttcc gacgcagaac tgtgtctttc
    16201 cggctatgtg ctgcccatcc agataattgc ggatagtccc gaccaccgta ctctgatccc
    16261 cctccaccaa gaagcgggga gttttcaact ccgccatcaa cggtttgtaa gagcggacga
    16321 aacgtcggaa agtacccgtc tgcaaacgac ggttcatgcc ataaacgaca gtt
//
