LOCUS       c00099_gnlPro..        15943 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IACLKOLK_99.
ACCESSION   c00099_gnlPro..
VERSION     c00099_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:30:54
            Original ID  :: gnl|Prokka|IACLKOLK_99
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 39017
            Orig. end    :: 54960
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15943
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[49017:52531]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15943
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15943
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             9..1016
                     /locus_tag="ctg99_29"
                     /transl_table=11
                     /translation="MMKLNLSDIRYNWVVIFIIQLLLSPGIDVFSQAMPVDTVYNQSYD
                     WRPGQRETLPEWVFASQRKGRVIGISDPCMKSEAARMLALQRAAYLYSLQQGVQLRLLS
                     DVFSTMETASNTYEDQRNKMLVLGVIEHPVQHVSYRIEHEYTSIFGEKFLEVSFTPSND
                     SCDFSYHSVSELMLLFTKERVEEEEVKFNLLLESDSCREQSDQSWFQLKGTQSFPQIIS
                     YMNGVAICSSQEGCWYEDAGFGGQDGLEKMDMRNAFWNAYMSSLVKALLLYPFSDVNVK
                     QVDDRFNGGTDFGCGLYREKVVAVLSIFPFIKDIRNNKLCVDWQITEQQNIIRK"
     CDS             977..2587
                     /locus_tag="ctg99_30"
                     /transl_table=11
                     /translation="LADNRTTKYNKEMRKNRIRILSMVVFSLCLPFSLFAQIDKDMKEF
                     DDFVKQQQKEFDDFVSEQNKEFAEFLKETWKEYDLQKPVARPQRPEPVKPVSFDHKKPA
                     TKPQEVKVGEVTRLPIPTVTPSATFSPSKGKTQVPVVPGGKDVAVEPEKDSAVLPEIKP
                     EVKPEETVPAKRSLSGVEFSFYSKDCVVNASLKNRLTLKGIAEKDISAGWETLSRSNYQ
                     PLIDDCLAFKKDNALNDYGYLLLTRKVATELCGSTHSDEIALMQMFLLSQSGYRVKVAR
                     MDNRLTLFYASGNMIYATCFITLNGVNYYRFDTTPDKTNSIYTYNRDFANAKNPVNMNI
                     TAPQPFSGTYVEKTLQAKAYPSVKVCSKVNSGLISFYKDYPQCDFSVYVGAPVSQEVQQ
                     TVLPSLQAAVQGKKQSEAANILINFVQTAFDYKTDGDQFGYEKPFFVDELFYYPYSDCE
                     DRAVLYSYLVRTLMGLDVVLLEYPNHMATAVCFDENIDGDYITVSGKKYIICDPTYIGA
                     SIGLAMSQFKNVAAKVLKY"
     CDS             2600..3886
                     /locus_tag="ctg99_31"
                     /transl_table=11
                     /translation="MKNIKKYLCAIVMMVISMTAFAQEDVFSGDWLGANKEGDLKVAFT
                     LNCDGNWQLNPYNENARCNGFMEVNMLEPGGRESLMATYEFYVESMNGNELTLSFVGGR
                     PEVDAGISGQCKVVYRDDKLSFTGLDKGGKDAAFNGLTLVKSGSGADAIADAAADDGVP
                     LGVKILAVLQLILYIAVVLFIVGHMFFVWYKGARYKEVFTVEGMLNKRLAAGMPEKMTD
                     EEITEAWKLMDEAFATWTVIEKTDDDEFRKPTKMKQIKKSVLLIDQVISMCPTDADVIE
                     RLNSLTDVINSGEERHFDGSRKLIWLGVIVGILMYWMMGVGMMFSTLIATGLYVVASRT
                     PQFLIDKRALRGGGNIHNGIFAGVFGLLAGAQTVRTIYKFNDGHKEYSDDHSQHWIALA
                     IGLVVLFVLAMMMAFWALLNYLRNYVLYF"
     CDS             4102..4395
                     /locus_tag="ctg99_32"
                     /transl_table=11
                     /translation="LKTKDEIIAILQNFKEEFGERYGIEKLGLFGSVARGEQKEDSDID
                     ICVKLQEPDYFTRMEIKESLEERFNAKVDVVSLTAIMRSLFRNHIEKDAIYI"
     CDS             4412..4606
                     /locus_tag="ctg99_33"
                     /transl_table=11
                     /translation="MLLFVEERINTTIERCGSVISVNDFLASPDKMDIFDATCMRLQTI
                     GETVKNIDNLTFIMQNGSL"
     CDS             complement(4684..4896)
                     /locus_tag="ctg99_34"
                     /transl_table=11
                     /translation="MSLVTHLRDNTVLLFRLHQQFTFIGSSDKRLFHIHMDAKLHRLYT
                     NREITMIGSRQEFSTRYFIPIQKFH"
     CDS             5046..6323
                     /locus_tag="ctg99_35"
                     /transl_table=11
                     /translation="MKHGIYILTILMALLSLPESGYASIPFFAVANDTIRRAVICFDAN
                     EAKVDLSYKNNNQVITILDSLLLGNLNTKYITALNVETFVSPDGDESYNRSLAARRNDS
                     IKEFLQRYNSDVSVDKIHFFSEGEDWSEFRKLVASDSNLPDREEVLILIDYHKNDVNKR
                     KQLLRKLNRGIAYRYIVRNIFPELRRSVITIVGETSKLGKEAFEPVSSVSGLFVSKQEE
                     ALPKDQPDKPVGESEKKQACEVDISEAEGPVKSQTVLAVKNNLLYDLALAPNIEVEIPI
                     GKRWSLNTEYKCPWWLNSKHDFCYQLLSGGMEGRCWLGNRQKRDRLTGHFIGLYAEGGI
                     YDFQLRGDGYQGKYYGAAGVTYGYARQLARHFSLEFSLGIGYLTTEYKKYTPYEGDIVW
                     TNSGRYNFIGPTKAKVSLVWLITTKR"
     CDS             6381..7331
                     /locus_tag="ctg99_36"
                     /transl_table=11
                     /translation="MLTGCSRRDILDDYPVSGVDIKLDWDGVTDQLPEGVRVIFYPKNG
                     DGRKVDKYLSVRGGEMKVPPGRYSVVVYNYNTESIRIRGEESYEAIEAYTGNCNGLGIE
                     GTEKMVWSPDSLYVLNIDELKIGKSDEALSLNWKLESVVKKYSFALEVKGLEHVMSVVG
                     CINGLSDSYYMGKGYGVSSSQPIYFEAKKEADKVIAYFTAFKWSKDVSIPILGRASGAM
                     GSRIKGDITLVLQFIKTDNTVQEETIDVTEIIDTLEDVGVKEEGKPTPPPEIELPPDDK
                     IEVEKPETPPNPDGGGIGGNVDGWGPEDNVELPVN"
     CDS             7387..8367
                     /locus_tag="ctg99_37"
                     /transl_table=11
                     /translation="MKKILLAVTAALAITSCSQNEEFENVGQNAEISFGTIVRNSTRAN
                     ILTTDNMQTFTVSGYQTDAEMAEGTKLTTGFIDELKVEKKDAKWVYEGDTFYWPYSGKV
                     QFFGTSPAQSLNINVAGYPTFDYTIKDVSAQEDLVAANLINKDKTSGELILPFQHLLTQ
                     VNFSIKGDTPGFTYTVTSIVLTDLQDKATFKFDGTNAVGAWQGATTSSANIKYEHTGSF
                     TVIPETDKEMVTNLEAVGKALFMLMPQEASSVKLAITYTAVKGTQKGFSGTKNVTLAGT
                     WTMGHSIRYILKLTSDTTPVTFGQPTSGEWIPESPQPGEIPTPAN"
     CDS             8537..9376
                     /locus_tag="ctg99_38"
                     /transl_table=11
                     /translation="MPSICQGTWDCQICPKAVSNAITHVIYQRGFHKPAQKCEENLILF
                     LMKGEILVNSKEYAGTMLKEGEFILQAIGSMFEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKEVSPPLIYTPLKIIPELQYFLNGSITYLKGDKVCRDLLSLKRKELAFVLGYYYSD
                     YDLSSLVHPLSKYVNSFQYFIIQNYKKVKTVEELAQLGGYTLSTFRRIFNNVFHEPVYE
                     WMLARRKEGIWDDLNNSECSISEICYKYGFESLPHFSNFCKKSFGASPRNLRRQDIS"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_39"
                     /sec_met_domain="Fer4_7 (E-value: 3.1e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 2.3e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.4e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(10793..12772)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.3; E-value:
                     4.6e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_40"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.2e-62, bitscore:
                     202.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.5e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             complement(12810..13514)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_41"
                     /sec_met_domain="SucD_FumR (E-value: 2.5e-131, bitscore:
                     426.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSSPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             complement(13726..14595)
                     /locus_tag="ctg99_42"
                     /transl_table=11
                     /translation="MPGDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLRERQIVLQAIGSKVEILALTDVEYVVYWFNELPLLCEDR
                     YREMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLSSFFYPISTYTESFHYFVMQNYSKVKNVEEFAHLGGYTTTTFRRLFKNLYGVPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
     CDS             14869..15831
                     /locus_tag="ctg99_43"
                     /transl_table=11
                     /translation="MLMLRKIVFFLFVFVGLSLFAQQDYMVSSYVRGNFYNRGRISTES
                     LRASDDLIFLNVHPNKDGSLSFENPRVFQGKGVTTWEGLIKSVRAKVKGTKVKIRLGAS
                     SGEWKAMVADKAARTTFAKNIKTVLEKNKLDGIDLDFEWAENEKEYEDYSLAILKMREV
                     LGDKYLFSVSLHPVCYKISKEAIEAVDFISLQCYGPSPVRFPIEKYCSDIQMVLEYGIP
                     KEKLVAGVPFYGVTKDNSKKTEAYFNFVQNGLVTSPAQNEVIYQGDTYVFDGQDNIRIK
                     TRYAKEQKLKGMMSWDLATDLPLSDSRSLLKTMTEELRE"
ORIGIN
        1 aagattgaat gatgaagctt aatttgtcgg atataagata taattgggta gttattttta
       61 ttatccagtt gcttttgtct cccggtattg atgtgttttc acaggcaatg cctgttgata
      121 cagtttataa ccaatcttat gactggagac cgggacagcg ggagactttg ccggaatggg
      181 tgtttgcttc tcaacggaaa ggccgggtaa ttggtatatc tgatccttgt atgaaatccg
      241 aagctgcaag gatgcttgct ttgcaaagag cggcttatct gtattcattg cagcaagggg
      301 tacaattgag acttctctcg gacgtttttt ccaccatgga gactgccagt aatacatacg
      361 aagaccaaag aaacaaaatg cttgtactgg gagtgatcga acatcccgtt caacatgttt
      421 cttaccggat tgagcatgaa tatacttcta tatttggaga gaaatttctg gaggtatctt
      481 ttactccatc gaatgatagt tgcgattttt cttatcattc cgttagtgag ttgatgcttt
      541 tgtttacgaa agaaagggtt gaggaagaag aggtgaaatt caatttattg ttggaatcgg
      601 atagttgtag ggagcaatca gaccagtcat ggtttcagct taagggaaca cagtcatttc
      661 ctcaaataat ttcatatatg aacggagttg caatttgttc ttcacaggaa ggctgttggt
      721 atgaagatgc cggtttcgga ggtcaggacg gattggagaa gatggatatg aggaatgcct
      781 tttggaatgc ctatatgtct tctttggtga aggcgctgtt gttatatccg ttttctgatg
      841 taaatgtcaa gcaggtggac gatcgtttca atggcggcac tgatttcggt tgtggtttgt
      901 atcgggagaa ggttgtcgct gtcttgtcca ttttcccctt tatcaaagat atacggaata
      961 ataagctgtg tgtggattgg cagataacag aacaacaaaa tataataagg aaatgaggaa
     1021 aaataggata cgaatactat ctatggtagt tttttcattg tgtttgccgt ttagtctttt
     1081 tgcgcaaata gataaagaca tgaaggagtt tgacgatttt gtgaagcagc agcaaaaaga
     1141 gtttgatgat tttgtgagcg aacagaataa ggaatttgcc gaatttctga aagaaacctg
     1201 gaaagagtat gacttgcaga agccggtggc acgtcctcaa aggccggagc ctgtaaaacc
     1261 ggtcagcttt gaccataaga agccggcaac aaaaccgcaa gaggttaaag taggggaggt
     1321 gacacgactc cccattccga cagtgactcc aagtgcgaca ttttctcctt caaaggggaa
     1381 aacacaggtt ccggttgtac cgggaggtaa agatgtggct gtagaaccgg aaaaggattc
     1441 tgcggtgctc cctgaaataa aaccggaagt gaagcctgaa gaaaccgttc cggccaaacg
     1501 ctcactttcc ggtgtagagt tttcgttcta cagtaaagat tgtgttgtca atgcttcatt
     1561 gaagaaccgg ctcactttaa aagggattgc agagaaagat atttctgccg gatgggagac
     1621 gttatcacgt agcaactatc agcctttgat agacgactgt ctggctttta aaaaggataa
     1681 tgccctgaat gactatggtt atctgctgtt gacgaggaaa gttgctactg aactatgtgg
     1741 aagtactcat tccgatgaaa tagctcttat gcaaatgttt ctcctttctc aatcgggata
     1801 tagggttaag gtggcgcgta tggataaccg ccttacttta ttctatgctt cgggtaacat
     1861 gatttatgct acctgtttta ttactttgaa tggagtaaac tattacaggt ttgatactac
     1921 cccggataaa actaattcta tttatactta caaccgtgat ttcgccaatg cgaagaaccc
     1981 ggtaaatatg aatatcactg ctcctcaacc cttttcagga acttacgtgg agaaaacgtt
     2041 gcaagcgaaa gcttatccat ccgtcaaagt ctgctcgaaa gtaaattcgg gacttatttc
     2101 cttctataag gattatccgc aatgtgactt ttctgtctat gtgggagctc ctgtcagtca
     2161 ggaagtacaa cagacggtgc ttccatcatt gcaagctgcc gtacaaggga aaaaacaatc
     2221 ggaagccgct aatatactga ttaatttcgt gcagacagct tttgattata agacagatgg
     2281 tgaccagttt ggttatgaaa agcctttctt tgtggatgag ctgttctact atccttattc
     2341 cgattgcgaa gaccgtgctg tgttatactc ttatttggta cgtactctta tggggcttga
     2401 tgttgtattg ttggaatatc ccaatcacat ggcaacagcg gtctgttttg atgaaaacat
     2461 tgacggagat tatataactg taagcggaaa gaagtacatt atttgtgatc ctacttatat
     2521 tggagcttct atcgggcttg ccatgtcgca atttaagaac gtggcagcca aggtgttgaa
     2581 atattaattt tattatatta tgaagaatat taaaaagtat ttgtgtgcca ttgtaatgat
     2641 ggttatttcg atgactgcat ttgcgcagga agatgttttt agcggtgact ggctaggagc
     2701 aaataaagaa ggcgatttaa aggttgcgtt cacattgaat tgtgatggta attggcaatt
     2761 gaatccttat aatgagaatg ccagatgcaa tggatttatg gaagtgaata tgctggaacc
     2821 cggtggaagg gaatctttga tggcaactta tgagttttac gtcgagagta tgaacgggaa
     2881 tgaactgact ctttcttttg taggtggacg tccggaggtt gatgccggga tttccggtca
     2941 atgcaaagtc gtttataggg atgataagtt gtcgtttacc ggacttgata aaggcggaaa
     3001 agatgctgcc tttaatggat tgacacttgt aaaaagcggt agtggagctg atgcaatagc
     3061 tgatgctgcg gcggatgacg gagttccttt gggagtaaag atattggctg ttctccaact
     3121 gattttgtat attgccgttg ttttatttat tgtggggcat atgttttttg tatggtataa
     3181 gggcgcacgt tataaagagg tttttacggt agaaggaatg ttgaataaac gccttgcagc
     3241 cggaatgccg gagaaaatga cggatgaaga gataacggag gcgtggaagc tgatggatga
     3301 ggcatttgct acttggacgg tgattgaaaa aacagatgat gatgaattca gaaagccgac
     3361 aaagatgaag caaattaaga aatctgttct tttgattgat caggttatca gtatgtgtcc
     3421 tactgacgct gatgtcatag aacgcttaaa ctcattgact gatgtgatta atagtggtga
     3481 agaacgtcat tttgatggtt ccaggaaatt aatctggtta ggtgtcattg tgggtatctt
     3541 gatgtattgg atgatgggag tcggtatgat gttttctact ttaatagcta ccggtttgta
     3601 tgtggtagcg agcaggacgc ctcaattctt aattgataag cgggcacttc gtggcggtgg
     3661 aaacattcat aatggtattt ttgccggagt gttcgggtta ttggcaggag cgcagacagt
     3721 gcggacaata tacaagttta atgatggtca taaagaatat tctgatgatc attcacaaca
     3781 ttggattgct ttggcaatcg gacttgtcgt tttgtttgta ttggcaatga tgatggcgtt
     3841 ctgggcactt ttgaactatt tacgtaatta tgttctgtac ttttgatgga taaaactaac
     3901 atgattgtta ataatggatt cggcagcata attaggctat ttatgttttg aagtagaatt
     3961 tagagtagta ggtgtacagg ggatcgatga aaattcgatg acctgtgcat cttattttaa
     4021 ttagtgatac tacaaaatat gattaagaat ctgctaattc caatattaat tttaatattt
     4081 gcattataac aatagtgtca gttgaaaaca aaagatgaaa taatcgctat tctccagaat
     4141 tttaaggaag aatttgggga gagatatgga attgaaaagt taggactttt tggttctgtg
     4201 gctcgtggtg agcagaaaga ggatagtgat attgatattt gtgtaaagct tcaagaaccg
     4261 gattatttta ctcgaatgga aataaaagag tcattagaag agcgttttaa tgcaaaagtg
     4321 gatgtcgtgt ctttaaccgc aattatgcgt agtttatttc gcaatcatat agagaaagac
     4381 gcaatctata tctaatgctg acatattgga tatgcttctt tttgtagaag aacgtattaa
     4441 tacaactata gaaagatgtg gtagtgtcat ttctgtaaat gatttcttag cttctcctga
     4501 taagatggat atttttgatg caacttgtat gcgtttgcaa accataggtg agactgttaa
     4561 gaatatagat aatctgactt ttattatgca aaacggtagt ctttaggtac cactcccatc
     4621 cgctttgtaa actccttata gaaatgtgat ctattcataa acccactttg atacatgatt
     4681 tcttcaatga aatttttgga tgggtataaa atatctcgta gaaaattctt ggcgactccc
     4741 gatcatagtt atttcccgat ttgtatagag gcgatgaagc ttggcatcca tgtgtatgtg
     4801 gaaaagccgc ttgtcagaac ttcctatgaa tgtgaattgc tgatgcaggc ggaacagaag
     4861 tacggtgtta tcacgcagat gagttaccaa agacattttt tctgtttatt attgacctta
     4921 aactctcaaa acttgcaaaa tcgtttcaat cgtttcacag aatctttcat gtcttgattt
     4981 ttgttctaaa agtatgattc ggtttgtttt ctaacttcta tatttgtcat tagaaacgaa
     5041 cgacaatgaa acatggtatc tatatattga ctattcttat ggctttatta agccttccag
     5101 aaagtgggta tgcttcgatt ccatttttcg ctgttgcgaa tgatacaatc cggcgggcag
     5161 tgatatgttt tgatgcgaat gaagcgaaag tggatcttag ttataaaaat aataatcagg
     5221 taattacaat tttagattct ttgcttctcg gaaatttgaa tacgaaatat ataacagcgc
     5281 tgaatgtgga aacttttgtt tctcctgatg gtgatgaatc ttataataga agtttggctg
     5341 ctcggagaaa tgattcgata aaggaattct tacaacggta taattcggat gttagtgttg
     5401 ataagattca ttttttttca gagggagagg attggtcgga gtttcgtaag ttggtggcat
     5461 ccgactccaa cttgccagat cgggaagaag tgctgatatt gattgattat cataagaatg
     5521 atgtcaataa acggaaacaa ctgttgcgaa aattgaatcg gggaattgct taccgataca
     5581 ttgttcgcaa tatctttccg gagctgcgaa gatcggttat tacgattgtc ggagaaactt
     5641 cgaaattagg taaagaggct tttgaaccgg tatcttctgt ctccgggttg tttgtttcaa
     5701 agcaggaaga ggcgcttccg aaagatcaac ctgataagcc tgtgggagaa agtgaaaaaa
     5761 aacaggcctg tgaggtcgat atatcggagg cagaagggcc ggtgaaaagt caaactgtgc
     5821 ttgcagtgaa gaataatctg ttatatgatt tggcattggc gccaaatata gaagtggaaa
     5881 ttccgatagg caagaggtgg tctttgaata ctgaatataa atgtccgtgg tggctgaata
     5941 gcaaacatga tttctgctat cagctccttt cgggagggat ggaaggacgt tgttggctgg
     6001 gaaaccgtca gaaacgcgac cgattgaccg gacattttat cggactttat gctgaaggcg
     6061 ggatatatga cttccagctg cgtggagacg gctatcaagg taagtattac ggagctgcgg
     6121 gagtgactta tggatatgca cggcaattgg cacggcattt ttcccttgaa ttcagtcttg
     6181 gcatagggta tttgacaaca gaatataaaa aatatactcc ttatgaggga gatattgtat
     6241 ggacaaatag tggacgttat aactttattg gtcctaccaa ggcgaaagtt tctttggtat
     6301 ggttgataac aacaaagaga taggagggcg taatgcgaaa tacaagatac gggtttcttg
     6361 tgcttttgtc ctcgctgctg atgctaactg gatgtagccg tcgcgatata ttggatgatt
     6421 atcccgtaag tggggtagat ataaagctgg attgggatgg agtgacagat caactgccgg
     6481 agggagttcg ggtgattttt tatccgaaga acggagatgg caggaaagta gataaatacc
     6541 tttcggtgcg aggcggagaa atgaaagttc ctccgggacg gtattcggta gtagtctaca
     6601 actataacac ggaatctata cgaatcaggg gtgaagagtc ctatgaagcg atagaagcct
     6661 atacgggaaa ctgcaatggt ttagggattg aaggaacgga aaagatggtt tggtcaccgg
     6721 attcattgta tgtgttgaat atagatgaac tgaaaatagg gaagagcgat gaggcacttt
     6781 ctttgaattg gaaactggag tcagtggtaa agaaatattc ttttgcgttg gaagttaaag
     6841 gtttagaaca tgttatgtca gttgtaggat gtataaatgg actgtctgat tcttattata
     6901 tggggaaagg atatggagta tcttcctctc aacctattta ttttgaagca aagaaggagg
     6961 ctgataaggt aatagcttat ttcactgctt tcaaatggtc aaaggatgta tcgataccga
     7021 tattaggaag ggcgtcagga gctatgggct ctcgtataaa aggtgatata acgttggttc
     7081 tgcaatttat taaaacagac aatacagtgc aggaagaaac gattgatgtt actgaaataa
     7141 ttgatacact tgaagacgtt ggagtgaagg aagaaggaaa gccaactcca ccaccggaga
     7201 ttgagctacc gcctgatgat aaaatagaag tggagaaacc agaaacaccg ccaaatccag
     7261 acggaggagg aataggaggt aatgttgatg gatggggccc ggaggataat gttgaattac
     7321 ctgtgaactg aatgggatac tataaacaaa atagaacaat attataaact ttaaaaaaat
     7381 atagttatga aaaagatttt attagcagtt acagctgctt tggcaattac gagttgctcg
     7441 cagaatgaag agtttgagaa tgttggacaa aatgctgaaa ttagttttgg tactattgtg
     7501 cgtaattcta caagagcaaa tattctgact actgataata tgcaaacatt tacagtatca
     7561 ggttatcaaa cggatgcaga aatggctgaa ggtactaaac taacaacagg atttatagac
     7621 gaattaaagg ttgagaaaaa agatgctaaa tgggtgtatg aaggtgacac tttttattgg
     7681 ccttattcgg gaaaagttca attttttgga acgtctcccg ctcaatcctt aaatataaat
     7741 gttgcaggtt atcctacttt tgattataca ataaaagatg tgtccgctca agaggattta
     7801 gtagcagcta atttgataaa taaagataaa acatctggag aattgatact tccatttcaa
     7861 cacttgttaa ctcaagtcaa tttttctatt aaaggagata ctccagggtt tacgtacact
     7921 gttacaagca ttgtattaac ggatttgcag gataaagcca catttaaatt tgatggaaca
     7981 aatgcagtgg gtgcttggca aggagcaact acttcaagtg caaatataaa atatgaacat
     8041 accggttctt ttacagtaat tccggaaaca gataaagaaa tggtaactaa cttagaagca
     8101 gttggtaaag ctttatttat gcttatgcca caagaggcgt catctgtaaa attggcgata
     8161 acttatacgg cagttaaagg tacgcagaaa ggattttccg gtacgaaaaa tgtaactctc
     8221 gctggtactt ggactatggg acacagtatt cgttatattc ttaaattaac aagtgatact
     8281 actcctgtta cgtttggaca gccaacatct ggggaatgga ttcctgagag tccgcagcct
     8341 ggtgaaattc caactcctgc taactaataa ttgcttaaag tcattttttt ctgtttattt
     8401 ttagaaagag tccttctaac aatattactt ttttgttaga aggactcttt tcacttttct
     8461 ctcttttttt atggcaatat gaaagatttc atatattttt gctggcagca taaacaaaaa
     8521 caaacacagt cagcgtatgc catctatttg tcaaggaact tgggattgtc aaatatgtcc
     8581 aaaagcagtg agcaatgcca ttactcatgt aatttatcag cgtggttttc ataaaccggc
     8641 tcaaaagtgt gaagaaaatc ttatcctttt tttgatgaag ggagaaatac tggtcaatag
     8701 taaagaatat gcggggacta tgcttaaaga aggtgaattt attcttcagg ctattggttc
     8761 tatgtttgag atgcttgcta tgactgaatg tgagtgcatt tattatcgtt ttattcagcc
     8821 cgaactgttt tgtgatttcc gtttcaatca tatcatgaag gaagtatctc ctccacttat
     8881 ttatactcca ttaaaaataa ttccagaact acaatatttc ctcaatgggt ctattactta
     8941 tttgaaaggg gataaagtct gtcgggattt gctatctctg aaacgaaaag aattagcgtt
     9001 cgtgttggga tactattatt ccgattatga tctttcgagc ttggtgcatc cactttctaa
     9061 atatgtaaac agtttccaat atttcattat tcaaaactat aagaaagtaa agacagtgga
     9121 agaactggca caattgggtg gatatactct tagtacattc cgtcgtatct tcaataacgt
     9181 ctttcatgaa cctgtttatg aatggatgct ggcgagacgt aaagagggca tttgggacga
     9241 cttgaacaac tctgaatgta gcatttcgga gatatgctat aaatatggtt ttgaatcttt
     9301 accccatttt tctaatttct gcaagaaatc ttttggtgcc tctccacgta atttacgtag
     9361 gcaagacatt tcataaatgc aactatgtaa gataattgcg gttcaccggt ttcacccaat
     9421 tctctaaatg ccgatgaata aggtaacagc gggtgaaagc aagggagaaa ttcaggtgaa
     9481 actgaacctt cttggtttca cctattgagt ttattcatac cgactgttgg acatatagct
     9541 ccaaggtgtt ggatatatag ctccaagatg ctggatatat agatgcaaca actcaagtat
     9601 taacacatga gaactaaggt gttaagactt ggcggccaaa gtattacatc cgtacagttc
     9661 actcattaat acctgaaagc ggatttgcta taagcatatc cggattagct ataatgataa
     9721 ttgttttagc tcaagggata ttttaataag acaggtgaaa gcggtaacga atgattttac
     9781 cttatttcag tcctcgcttt cacccgtaat tctctcattc ataccagttt tggctataag
     9841 gtgaaatcgg tgaaacttat gaattaaaag ttcatgttac tgatccgtat taataataat
     9901 tgtgatctac tcatatataa agaaatcccc tgtcgaacta gccggcaggg gattctgtca
     9961 ttaatcaaat taagctctcg ctattgaaat ctagcaattt ctagtctttt aattttgcga
    10021 tgatgaagtc gcggttcaag cgagcgatgt tgctgataga aatattcttc ggacattcag
    10081 cttcacaagc acgagtgttt gtacagttac cgaatcccag ttcgtccatc tttgacaaca
    10141 tagcttttgc acgacgcaaa gcctccggtt taccttgcgg cagcaagttc aactggctaa
    10201 cttttgcaga aacgaacaac atagcagaac cattcttaca tgcagctaca caagcaccgc
    10261 aaccgataca agaagcagca tccatagctt cgtcagcgat aggtttcgcg atcaggatag
    10321 cgttagcatc ctgcggagca cctgtgcgta cgcttacata accaccagct tgcataatct
    10381 tgtcgtatgc agtacggtct accatcaagt ctttgatgac agggaaacca gccgaacgcc
    10441 aaggttcaac agtgatggta tcaccgtcgt tgaaacgacg catatagatt tggcaagtag
    10501 tagcacctgt tgcaggaccg tgcgggtgtc cgttgatgta aagagaacac ataccgcaga
    10561 taccttcgcg gcagtcatga tcgaatacta ccggttcttt tctttcgctg atgagctgtt
    10621 cgttcagaat atccagcatt tcgaggaagg aagtatcacc ggggatatct ttcatttggt
    10681 aggtttcaaa agcaccttta gctttcggac cagcttggcg ccataccttc agtgtaaatg
    10741 atatattttt atccattttc ttctaattct tttaaatgtt taacttcacc gattagctct
    10801 tgtagttacg agtctgaacc ttgatagctt cgtataccag cggttctttg tgcaataccg
    10861 gagccttttc atcgtcacct tgatattccc agcatgctac atagaagaag ttttcgtcat
    10921 cacgttttgc ttctccttct tcagtctggt attcttcacg gaagtgacca ccacaacttt
    10981 cgttacggtt caatgcatcg taagcaacaa gctcacccat agtgatgaag tcgtacagac
    11041 ggattgcttt gtcaagctct acgttcatac cttccttaga accggggata aacaagttcg
    11101 tttcgaattc cttgcggatt tctttcagtt cggcgatacc tttcttcagg ccttctgccg
    11161 tacgtcccat acctacatat tcccacatga catgacccag tttcttgtgg atagaatcaa
    11221 cagattcttt accctggatg ctcatgaact tgtcgatctt agcttgaact gctttttcag
    11281 cttcagcaaa ttcaggaaga tcggtagaga aacgaggaac agtgatctgg tctgccagat
    11341 agttctggat agtgtaaggc aatacgaagt aaccgtcagc caaaccttgc atcaatgcag
    11401 aagcaccgag gcggtttgca ccgtggtcgg agaagttaca ttcaccgata gcgaacagac
    11461 ccttgatagt ggtttgcagt tcgtagtcta cccagatacc acccattgta tagtggatag
    11521 ccggataaat catcatcggg ttataatatt tcacaccact gatttcttta gccagttcgc
    11581 ccggattaac gtcagtgatt tcttcgtaca tatcgaagag gttaccataa cgttgaagaa
    11641 caacgtcgat acccaaacgg ttgatagctt cagagaagtc gaggaatacg gccaaacctg
    11701 tgttgtttac accgaaacca gcgtcgcaac gttctttagc ggcacggctg gcaacgtcac
    11761 gcggaaccag gttaccgaat gccggatagc ggcgttccaa gtaatagtcg cggtcttctt
    11821 ccggaatatc acttcctttg atttcgcctt tctggagttt tacagcatct tctttcttct
    11881 tcggaaccca gatacgaccg tcgttacgga gagattcaga catcaaagtc agcttagact
    11941 gcttgtcgcc atgtaccgga atacaagtcg ggtgaatctg aacgtatgca ggatttgcga
    12001 atacagcacc cttgcggtag caagagatag cagctgtaca gttacaaccc atagcgttag
    12061 tagacaggaa gtaagcgtta ccataaccac cagtagcgat tactacagcg tgagcggcga
    12121 aacgttccaa ttcgcctgtt acaagatttt ttgcgatgat accgcgggca cgtccgtcaa
    12181 cgatgacaac atcctgcatt tcgtagcggg tatacagttt aacagtacct acgtttacct
    12241 gacggctcaa tgcagagtaa gcacccagca gcaactgctg accagtctgg cctttagcgt
    12301 agaaagtacg ggatacctgt gcgccaccga aagaacggtt atccagtgta ccgccatatt
    12361 cgcgagcgaa aggaacacct tgcgctacac attggtcgat gatagcgtta gacacttcag
    12421 ccagacgata tacgttagct tcacgggcac gatagtcgcc accttttaca gtatcgtaga
    12481 acagacggta aacggagtca ccgtcatttt gataattctt tgcagcattg ataccaccct
    12541 gtgcagcgat agagtgtgca cgacggggag aatcctgaat acagaaattg aatactctga
    12601 aacccatttc accaagtgaa gcagcggcag aagcacctgc cagacccgta cccacaacga
    12661 tgatgtccaa acgacgttta ttagcggggt tcaccaattt ctggtgagct ttatagttgg
    12721 tccatttctc agccaccggg ccttctggaa tttttgaatc tatcttgatc ataatattat
    12781 ttacaattta atcatttaca atttactatt tagcaagcac cgccacaaat cagtgttttc
    12841 acgaagaata ccactactac cagtgcgaaa ccgagtacaa caatcgtaga atagatgtta
    12901 gaaatacatt tccaacgatt gatccatact ttgttgttcc atcccagtga ttgcatagag
    12961 ctccagaaac cgtgagtcag gtggaaccac aaagcaaaca gccaaacgag gtaaagaact
    13021 acgtaaaccg ggctagagaa agtctgctgg atgtgataag caccgttagc ggcataagcc
    13081 agcgtcagtg tatcagcgtg catgcccatg ttgtgcatca gttccggcaa ctgcattttt
    13141 gcccagaagt tgaagaggtg caaaccaaga cctacgataa cgatcagacc cagcaccaac
    13201 atgttttgag atgcccattc tacagttttt ggtttgtcaa ccactgcata gcgttcgcta
    13261 ccacgcgctt tgcgattctg cattgtcagc cagaatgcgt agatgatgtg aatcacaaaa
    13321 agagcggcta gtcctgcggt agccactaac gcataccagt ttgctcccag gaactcacaa
    13381 atcatgttgt aaccatcagc cgagatgatt gcaaccaagt tcatcgccat gtgaaatgtt
    13441 agaaacagga caagggcgat accggtaacg ctcatcacca ctttccttcc tacagatgaa
    13501 ttacttaacc acataaatga ttgaatttaa attatttaat tgttagaact aaaatttcga
    13561 cgttttacac ctcttacaga ctgcaaaaat aggggaaata gattgattga gcaaggaatt
    13621 aaagaaataa ttctttaata atgaatcaat gcgctaatgt atcaatatgc cagccagtat
    13681 gcgcgcatgg tgcaactgat tggcacatta gtaggatgag gctgtttatt gtactttccc
    13741 gattttctca ccgccggctg ctttcttgcg taaagcgcgt ggggtatctc cgaaagagtc
    13801 tttacaaaag tgggcgaaat gcgacaggga gtcgaatccg tatctgttac agatttcagt
    13861 gattcgcatt ttggtgtgct gtaggtcttc caggattcct tcccgtttct tttccagtat
    13921 ccattcgtat acgggcacac catagaggtt tttgaatagt cggcggaaag tagtggtcgt
    13981 atatcctccc agatgcgcaa attcttccac gttcttcacc ttgctgtaat tctgcatgac
    14041 gaaatagtgg aaactttccg tataagtgct gatcggatag aagaatgaac tcagttgggg
    14101 cagcggataa aagttggtaa tcaagaaaac cagttctttg cattttaagt cgatatactt
    14161 gctgcaaggg ttttcctcag cgaggaattc gggcatactg gtgacaaggt ggtaaagcct
    14221 ttcgctcata atcagtggag tgtaggtcaa aggagcttcc gcctgttcca tcatttccct
    14281 atatcggtct tcgcaaagca aaggcagttc gttgaaccag tagacaacgt attcaacatc
    14341 tgtcagtgcc agtatttcga ccttggagcc aatagcttgc aaaacaattt gtctctcgcg
    14401 taacgttatt ccgggatgct cttcgctatt gataagtaat tcgcccttta tcataaaaag
    14461 catacaattc tgcgtacact tatccttggg gatatgctct cctttaggta agtttctata
    14521 tacaaggata ttctcaacat tttttggaca tcccgtacag ttggtatatt gtatgcaaaa
    14581 tgaatctcct ggcatgagtt ttatgcgtga tttattatct taacggaaca aagataggct
    14641 ttttttgcgg aaaatggaac tctttctttt atttatgttt tagtagaaac ctgcaaatat
    14701 tattcttatc cctttggatg atgttaaaga attcaatatt tatctgttgt aaatttctga
    14761 atagaaaact ttatgttgat ttttggaagt attatagttg tttttgaaca tctgtttccc
    14821 tttgatatgc gtatttttgc aatctaaacg ttttaattat caatcattat gctaatgcta
    14881 agaaaaattg tattcttcct ttttgtgttt gttggattat cattgtttgc acaacaagac
    14941 tatatggtca gttcttatgt gcggggtaat ttttacaacc gtggtcgtat ctctacagaa
    15001 agcttgcggg caagtgacga ccttattttc ttgaatgttc atcctaataa agacggatca
    15061 ttgtcatttg agaatccacg tgtatttcag ggaaaagggg tgaccacttg ggaaggtttg
    15121 attaaatcgg ttcgtgcaaa agtaaaaggt acaaaagtga aaatacgttt gggtgcttcc
    15181 agtggcgaat ggaaagcgat ggtggccgat aaggccgctc gtacgacgtt tgcaaagaac
    15241 ataaagactg tactggaaaa gaataaactg gatggcattg atcttgattt tgagtgggca
    15301 gagaatgaga aagagtatga ggattatagt ttggctatcc tgaagatgcg ggaagtgttg
    15361 ggagacaagt atcttttcag tgtatctctg catcctgttt gttataagat tagtaaggaa
    15421 gctattgaag ctgttgattt tatttcactt cagtgctatg gtccttcacc ggttcgcttt
    15481 ccgatagaga aatattgttc ggatatacag atggtattgg agtatggtat tccgaaggaa
    15541 aaactggtgg caggagttcc tttttatggg gtgaccaaag ataattcaaa gaagacagag
    15601 gcttatttca attttgtaca gaatggattg gttacgagtc ctgcacagaa tgaagtgatc
    15661 tatcagggag atacttatgt gtttgacggt caggataaca ttcgtatcaa aacccgttat
    15721 gcaaaggaac agaagctgaa aggtatgatg agttgggatt tagctacgga tttgccgtta
    15781 agtgacagca ggtcattact aaaaacaatg actgaagaat tgagggaatg acttagttcg
    15841 cacgactgct gcttgtaaat ccttttttct gtgtggtgat attaggacta aagaatgtta
    15901 atttaaacaa tctttcttta taaacatctg taattcaatt aat
//
