LOCUS       gnlProkkaPIHOFJDL_24   10460 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PIHOFJDL_24.
ACCESSION   gnlProkkaPIHOFJDL_24
VERSION     gnlProkkaPIHOFJDL_24
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:15:31
            Original ID  :: gnl|Prokka|PIHOFJDL_24
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 67092
            Orig. end    :: 77552
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10460
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10460
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10460
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2129..3163
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_42"
                     /sec_met_domain="PF04055 (E-value: 5.2e-18, bitscore: 57.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
     CDS             3182..4222
                     /locus_tag="ctg24_43"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             4227..5321
                     /locus_tag="ctg24_44"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             5331..6572
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg24_45"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             6559..7086
                     /locus_tag="ctg24_46"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             7092..7865
                     /locus_tag="ctg24_47"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             7872..8267
                     /locus_tag="ctg24_48"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             8515..9903
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg24_49"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             10001..10351
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_50"
                     /sec_met_domain="PqqD_RRE (E-value: 3.8e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.4e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
ORIGIN
        1 tatgctcatt tccagttgaa tggcttttca caggcggatg ccaagtcgtt ctcaaagcaa
       61 tatttgtcta cttactccaa ggctttgtct gcacagcagg aagatattct tgcttcgtgg
      121 gtgctggcta aacaaccgcg ctgtttgagt gtattgctca acgagctggt ttcgttcggt
      181 cagtacgatg ctctcaatga atatatgcgt ggatattgcc ggctcaatga ggttgggcaa
      241 ttctatgaca gtgtgctacg gcgtttgtcg gctgattatg gttccgaaga gattggaaga
      301 acgcttctga tgctttcact tactttagaa ggatttaccg aagatgaagt gaagagcatg
      361 gcagacatta atcagatact ttggtcgcag ttgagagtgg aaatgagcag ctggctcacc
      421 aacaaaggag gacgatattg cattggtgac acacaaatgg tagaggcgat cgaacgctat
      481 ttcgctcaag atgacgaatg tatagatgat agtcgccatg aaattatttc cgctctgctg
      541 gatgaggaag agatcctttc ccatccgttg acttttgccg attataacta tcgcatgaaa
      601 cagttctgct accatgattc gtatcgctat aaagtggaga ttacctatca atgctataag
      661 atgcaagaat gggatatatt gaaggattgg atttgtgatg tggagatttt cgagattctg
      721 tatcgcacga atcgttctct gttggaagat agctggaagg cgatcatgaa cgacaatcct
      781 gaagttacgc ctgaagtcta tgccgaattg gactttgatg agatcgattc ttttttaatt
      841 cctgtcattg ctaatgatat ggctactttc ttgagcagtt ctttccatct gacgaaggcg
      901 gcagctgctg tgagtgagaa gagtatggaa ggtgctgcca tgccactcat tgccaagtcg
      961 gtattgaaga tgaatgaggg atgtcggtat gcccgtaatg aagaatacga aacggcatgc
     1021 gactgtttcc tgaaagcatt ggtgatgcag gagaacatag taccgactcc ggaactggag
     1081 attgccaaca cctgtcgaaa tctagctttg gcatattact acaatgagca atacaatgaa
     1141 gcggcgatct atttgaatag ggcgcttgat tatcatgcgg cttctgctga cgagaagagt
     1201 caggcagaag tcattgaact ttccgaatat ctggcttatt gtgattacta taaggatgag
     1261 gaagagagtg ctgccgagaa attccggaaa gtagctgaaa tgcacgagtc gttgaatggc
     1321 agactgtccg gtggagtggc taaatgtttg cgtatgcagg gtaaatgtct ttattatatc
     1381 aaacgatacg atgaagcatg gatgctgatg aatcaggcgt tggacattgc tatacagata
     1441 gataataaaa aacagatcgt cgcttgtcat aaacagttgt attatctgtg cagggaattc
     1501 aaacggatga tgaatgaacg tggcgatgag caggcgtcta ctttattctt ccgtgagtct
     1561 cttctgcatg aaatgtattt cagcgaaaaa ccgcgtctgg cggaactgac tgtccgatat
     1621 gaggcattga gatgtgatat tatgcagcag tattacatga ataaagacta tgataacgtg
     1681 attcgtattg cgacgtcttt ggatattcac gatgatgctg accctaatgc ttcctgtctg
     1741 gtatattatt acaaagcaca ggcttatgtg aagttggaga attatccaat ggcgaaagag
     1801 gctttcttca gagagttcga actgcgaaag aagtatttgg gatgggagga agaagatacg
     1861 attctggctt gtcagaactt aggggttttg tacagctttt gtaatgaacg ggaagaggcg
     1921 ctggcttgtt tccgtgaggc gtacggtcat gaagtgaaaa agaatggcga ggattctgaa
     1981 atggcgcaaa agctacttca atatatcagc gtggttgaat cataacggag gcatacttcc
     2041 cttttttgtt aacttttaca ttcctgctat acggaaatcg actttatttc cttacatttg
     2101 cagatataaa ctatcaacag aaagaagaat gtctaaatat ccccttttag gaatgactct
     2161 tgtagagctt caatcattga caaaaagact gggtatgccc ggctttgctg ccaagcagat
     2221 tgcatcctgg ctttacgaaa agaaggtagc ctcgattgat gatatgacta atttgtcatt
     2281 gaaacaccgg gagttgctca agcagaacta tgaggtggga gcagaagctc cggtagatga
     2341 aatgcgctct gtagatggta cggtgaagta tctttataaa gtgggtgaga accattttgt
     2401 agagtcggtt tatataccgg atgatgaccg ggcaacgttg tgcgtgtcgt cacaagtagg
     2461 ttgcaagatg aattgtaagt tctgtatgac cggtaaacag gggtataccg ctaacctgac
     2521 cgccagccag atcatgaatc agattcattc gctgccggaa cgggacaaac tgactaatgt
     2581 cgtaatgatg ggaatgggcg agccgctcga taacctggat gaggtattga aggcattgga
     2641 actactgacc gctacctacg gttacgcatg gagtccgaag cgtatcacgc tttctactgt
     2701 cgggctacgg aaaggattgc agcgttttat tgaagaaaac gactgccacc ttgccatcag
     2761 ccttcactct ccgctgaccg ttcagcgtgc tgaattaatg ccggcggaaa aggcgttttc
     2821 aatcaccgaa atggtggaac tgttaaaaaa ctatgatttt agtaaacaac gtcgactttc
     2881 gtttgaatat attgttttta aagggctcaa tgattcgcag gtctatgcca aagagttgct
     2941 gaaacttctt cgcgggctgg attgcagggt gaatctgatt cgttttcatg ccataccggg
     3001 ggtagacctc gagggggcgg atatggatac gatgacccgt tttcgtgatt atctgacatc
     3061 acacggactt ttcaccacta tccgttcatc caggggcgaa gatatttttg ccgcttgcgg
     3121 tatgctgtcg acagcgaaac aggagaaaaa taatgaaagt taatatataa aaccgaacat
     3181 catgaaaaag tattctttta ttttatgcat cgctttggta gcctttgtcg ttgcatcttg
     3241 tggtctgaaa ggaaatcaca cctctagtgg tcgtgcttac gagcttttgg ttgtagtaga
     3301 tcacggtgtt tgggatcgtg ctgccggaag ggctttacat gatgcgctcg atgctgatat
     3361 gcccggtttg ccgcagtcgg aaccttcttt ccggattatg tatacttcgc cgaaagatta
     3421 tgattctacg ctgaagttga tacgtaacat tattattgta gatatacagg atatatatac
     3481 gaaagcctcg ttcaaatatg cgaaggacgt atatgccaat ccgcagatga tattgactat
     3541 ccaggctccg aacgaagaag agttcgagaa gtttgtggaa gagaacaaaa agacgattgt
     3601 cgacttcttt acccgtgcgg aaatgaaccg tcagattacg ttcctggaag ggaaacacag
     3661 taatttcatt tcgcagaaag tggacagttt gttcggatgc gacatctggg tggatgccga
     3721 actggctaat tcaaagaccg gggatgattt cttctgggct tctaccaaca caggtactgc
     3781 cgaccgtaac tttgtgatgt actcttatcc gtacactgac aaggatacgt ttaccaaaga
     3841 atattttgtg cacaaacgtg actccgtgat gaaagccaat atccccggat tcaaggaagg
     3901 cgtttatatg tcgaccgata gtttgctgac cgatgtccgt ccgatcaatg tacagaacag
     3961 ctacacaatg gaagcacgtg gcctgtggcg tatgaagggc gactttatgg gtggtccgta
     4021 tgtgtctcat actcgtctgg acgagaaaaa ccaacgaatt attacagcag aaatatttgt
     4081 ttattcacct gataaaatga aacgcaacct ggtacgccag atggaagcat ctctgtatac
     4141 actgaaactt ccgaatgaag ttcagcagaa gcagattcca ttgggagaag catctaagga
     4201 agcggaacaa actaataaat aaaaacatgg aagataacaa gataaggata ggtatcaccc
     4261 aaggagatat taacggggtg ggctatgagg tgattcttaa gacattttcc gaccctacga
     4321 tgttggaact atgtactccg attatttatg gctcaccgaa agtagcggct tatcatcgca
     4381 aagcgctgga tatacagacc aatttcagca ttgtcaactc tgctaccgaa gcggggtaca
     4441 accgtttgag cgtggtgaac tgtacggatg atgaggtgaa agtggaattt tccaaacccg
     4501 atcccgaagc cggtaaagct gcgctggggg ctttggaacg tgccatcgaa gaatatcgcg
     4561 aagggttgat agatgttatc gtaacagctc cgatcaacaa acatacgatt cagtcggaag
     4621 agttctcctt ccccggacat acggaatata tcgaagaacg tctgggcaat ggtgataagt
     4681 cattgatgat tttgatgaag aatgacttcc gggtggcttt ggtgacgaca catatccctg
     4741 tcagagagat cgcgactacg attaccaaag aactgattca ggagaaactg atgatattcc
     4801 atcgttgtct gaaacaggat ttcggtatcg gcgctccgcg tattgcggtg ctctctctca
     4861 atcctcatgc cggagacggt ggtttgttgg gaatggaaga gcaggaagtg attatccctg
     4921 ccatgaaaga aatggaagag aaaggaatcc tttgctacgg tccttatgcg gccgacggct
     4981 ttatgggttc gggcaattat actcattttg acggtatcct ggcgatgtat cacgatcagg
     5041 ggctggctcc gttcaaggcc ttggctatgg aagacggggt gaactatacg gcaggcctgc
     5101 cggtagtacg tacttctccg gctcatggaa cggcatacga tattgcaggc aagggattgg
     5161 cttgtgaaga ttctttccgt caggcaatct atgttgccat cgatgtgttc cgtaatcgtc
     5221 agcgggaaaa agtggctcgt gccaatccgt tgcgtaaaca gtattacgag aaacgtgacg
     5281 atagtgataa actgaagctg gatacagtag acgaagatta aaaacgagtg atgacgagag
     5341 cagagataca acaagtgaaa cagcgtttcg gtattattgg aaatactgaa gcattgtcgc
     5401 gcgccataga tgttgccatt caggtagctc ctaccgattt gtctgtgctg attaccggag
     5461 aaagtggagt cggaaaagaa agttttccgc agattattca tcaatatagc cggaggaagc
     5521 acggacagta tattgctgtc aactgtggtg ctattccgga gggcacgatt gattccgaac
     5581 tgttcgggca tgagaagggt gcgtttaccg gtgcgattgg cgaacggaaa gggtactttg
     5641 gcgaagccga cggcggtact atttttcttg atgaagtagg ggagttgccg atgtctaccc
     5701 aggcacgttt gctccgtgta ctggagagtg gtgagtttat gaaagtaggt tcgtccaaag
     5761 tacaaaaaac ggatgtgcgt gtggtggcag ctaccaacgt caatctgaca caagcgattg
     5821 cagaaggacg tttccgtgaa gatttatatt accggttgaa tacggtgcct atccagatac
     5881 cgcctttgcg tgaacgtggt gacgatgtac tcttgttgtt ccgtaagttt tccgcagact
     5941 ttgcagagaa ataccggatg cctgctatcc agttgacgga ggatgcgaag aaagagttat
     6001 tggcttaccc gtggcccggc aacgttcgtc agttgaagaa catcaccgag caaatatcta
     6061 tcattgaaac caacagggag atctctgctg ctatcttgca gaattatctt cctgcacaaa
     6121 atacgcaacg tcttcccgcg ctgatgggaa cgcgtgagag taaaggcttt gagagcgaac
     6181 gggagattct ttattctgtt ctgttcgata tgcgccagga agtggcggag ctgaagaaga
     6241 tggtgcacaa cctgatggcg gaacgtgccg gacaggtggg gcaggtaggg caaatgggaa
     6301 cggtggttac tactccggta gtgacggcgc atcaaccttc ggtacctgct atcattcaca
     6361 ccatgcagcc tacggtttgc aaggatgacg atgacataca agacacggaa gaatatgtag
     6421 aagaatctcc tttgtcactg gacgaagtgg agaaagaaat gatacgcaag gcacttgaga
     6481 ggcatcatgg aaagcggaag agtgcggcca aggacttgaa tatttccgag cgtacacttt
     6541 atagaaaaat aaaagaatat gaattggatt aagaaaataa tacgcccttt gctactgttc
     6601 ggcttgccgt tggtagtcat tgcgtgcact gtttcctata agtttaacgg atcgtctatc
     6661 aattatgata aggtaaagac catttcgata gccgacttcc cgatcaagtc ggagtatgta
     6721 tatgctccgt tggcaaccaa attcaatgag gacctgaaag atatcttcat ccggcagacc
     6781 cgtctgcaac tgctcaagcc gagtcaaaat gccgacttgc agattgacgg agaaatcaca
     6841 gggtacaatc agtacaacca ggcagtatct gccgacggtt attcttcgga gacgaagttg
     6901 actatcaccg tcaatgtgcg ttttgtcaac aacaccaatc atgccgaaga ctttgaacaa
     6961 cagttttctg cgttccgtac ctacgactct acccagttgt tgactgccgt acaggacgga
     7021 ttgattgctg aaatgtctaa agagatcacc gaccaaattt ttaatgcaac tgtagcaaac
     7081 tggtaatata aatgacttct gttaactttc aacaatggat tcagcatccc gagacgctga
     7141 atagggatac tttgtacgaa ctgcgcaatc ttcttgcgag gtatccgtat tttcagtcac
     7201 ttcgtctgtt gtatctgaag aatctgtata ttctccatga tattagtttc ggtggagaac
     7261 tgcggaaagc agttctttac attgcagaca gacggcagtt gttccggttg attgaaggtg
     7321 accgctatga tgtgcaggca cggaaaaagg gagtacctct cacggaggtg ctgaaagacg
     7381 aaccgtccgt agaccgcaca ttagcattga tcgacgcttt cttgtccaca gtacccgaag
     7441 aggtgactgc ccggaccagt ttcgactatt cgatggatta cacctctttc cttttggagg
     7501 agactccggc cacggaacag ccggctgaag aaacgcccaa actcaaaggc ttcgaactga
     7561 ttgacgattt tatagaaaag agcgagagcg actctcccct ctgcatgaaa cctttaagag
     7621 aagaaatgcc atcttcgcca acctcttcgg acgaacttac cgaagaagaa acgataaagg
     7681 aagaagagga agatgacagc tgttttacgg aaactttggc aaaaatctat gttaaacagc
     7741 aacgatattc aaaagctctt gaaataatta aaaaattaag cttgaaatat ccaaaaaaaa
     7801 atgcttactt tgcagaccaa atcagatttt tggagaaatt gattattaac gctaattcaa
     7861 aataactaaa aatgtactta ttattcgtta tcttaatggt tattgcagcc ttgttgatgt
     7921 gtttcatcgt gctgattcag aactcaaaag gaggcggact tgcttctggt ttctcttcat
     7981 ctaacgccat catgggcgtg cgcaagacta cagactttct ggaaaaagca acatggggcc
     8041 tggccatctt tatggttgta atgagcattg ctactgctta tgtagttcct cgctctgctg
     8101 ttgctaaaga cgcagtgttg gaacaggcac agaaagaaca acagactaac ccgtataact
     8161 tacccgcagg tacggctgcg ccgcaaactg aagctcctgc taccaatgca cctgctacag
     8221 aaactccggc accggctact gaaactcctg ctcctgcagc agagtaattc actccgtcgt
     8281 caagtaagac tttggggtaa aaccattaat gggaaggtgc agacggatgc tgcatttctt
     8341 tgatatttaa gtgcggatta cgcagattac acggattttc aatgttccgc gtggtcagtg
     8401 taatccgcac ttaacttttt cttgtaaaaa caatctcttt gtgatagaaa caaacgagat
     8461 ttaactacct ttgttggctg tataagatta ttaactactt ttttaaatat aacaatgaca
     8521 gaacatttga aacagaaatt gaatgactcc gccgtactcc gatggagtgt tctagcattg
     8581 gtcgcattta ctatgctatg cggctatttc ctcaccgacg taatgtctcc tctaaaaccc
     8641 atgcttgaga aagaactact atgggacagt cttgattatg gtttcttcac aagtgcttac
     8701 gggtggttta atgtattcct attgatgctg atcttcggtg gtatcatttt ggataagatg
     8761 ggagttcgtt tcaccggaat gggggcttgc ttattgatgg tgtttggttg tggattgaaa
     8821 tactatgcga tttctactac ttttccggaa ggtgccatgc tcttcggatt caaaacacag
     8881 gtgacgttgg ctgcattggg atatgctatc tttggtgtag gtgtggagat tgctggtatc
     8941 actgtttcca agattatagt gaaatggttc aagggcaagg aaatggcatt ggctatggga
     9001 cttgaaatgg ctacggcacg tatcggaaca actctggcga tggtattgac agttcctttg
     9061 gcagactttt tcggatctac ggatgagagt ggcacattcc atacaaatat tcctgctccg
     9121 attttgtttt gtctgattat gttgtgcgtg ggtacgattg cttttttcct ttatactttc
     9181 tatgataaga agttggatgc ttctttggat gcagagggat tggaaccgga agaaccgttc
     9241 cgtatgaaag atattgtgta tattattacc aataaaggat tctggttgat tgcattacta
     9301 tgtgtattgt tctactcggc tgtattcccc tttatcaagt atgctgccga cttgatggtg
     9361 cagaaatata acgtagatcc gaagttggcg ggaacgattc ccggattgtt gccgattggt
     9421 gcgattatcc tgactccgtt gttcggttcg ctttatgacc gtatcggtaa gggagccaca
     9481 ttgatgataa tcggatcagt gatgcttatt tttgtgcata cgatgtttgc tctgcctata
     9541 ctgaatatat ggtggtttgc tactatcatc atgattatat tgggatttgc cttctcgttg
     9601 gtgccttcag ctatgtggcc gtctgttccg aagattattc cggaaaaaca gttgggtacc
     9661 gcatacgcat tgattttctg ggtacagaac tggggattga tgggtgttcc tttgttgatc
     9721 ggatgggtgt tgaatactta ttgcaaaggt ccggtagtag acggtgcaca gacttatgac
     9781 tacacgttgc cgatgactat ttttgctctc tttggtgtac ttgctctgat tgtggctttg
     9841 atgttgaagg cagagaacaa gaagaaggga tacggtctgg aagaggcgaa tatccaaaag
     9901 taactgggaa attcaatacc taaagtaaca aaggaatttt gtatcaaggt gtaaacaaaa
     9961 gggtatcagt atgaatactc tgaaataaaa aataagaagt atggctgcca aagagaaaat
    10021 caacctgtta gaggtcattc cctgtcgcag tgaacatatt acagcagaaa gggaagggga
    10081 gacaattgtg ctctcctttc cccgttttaa atatccgtgg atgcaacgct tccttgtgcc
    10141 gaaaggaatg tcgaaagaac ttcatgtgaa attggaagaa cacggtacgg ctgtatggga
    10201 actgatagat ggaaaacgca atgttcgtga gattatagaa aaactcgcag accattttca
    10261 aaatgaagag ggctacgagt cgcgtgtatc ggcttatctt tctcaaatgc agaaagatgg
    10321 atttataaaa ctggtgatac cagtcgcata aataggaatt tatatttcac cacagaggcc
    10381 acggaattct aagacctatg caaataatag gcctataaaa aacagttaaa gaagttaaac
    10441 gggctatttc agtccgttta
//
