LOCUS       c00233_gnlPro..        21551 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BJLCDPEL_233.
ACCESSION   c00233_gnlPro..
VERSION     c00233_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:43:17
            Original ID  :: gnl|Prokka|BJLCDPEL_233
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 21551
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21551
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5277:15091]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_eut-pdu-related"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5278..15091
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_eut-pdu-related"
                     /protocluster_number="1"
     cand_cluster    1..21551
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="GR_eut-pdu-related"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..21551
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="GR_eut-pdu-related"
                     /region_number="1"
                     /rules="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(21..485)
                     /locus_tag="ctg233_1"
                     /transl_table=11
                     /translation="VADEIIITNRGRIEQKGTPLEVYQNPDTAFTAGFFGQTSVIDDYQ
                     VFNHFKEVPGGEKAIVRPEFVKVTKKNEEQKYKSSATEGIVERVAFRGSSLELKVRVGN
                     ATLSARRSLDEEPVREGEVVDVFVQRIFVTKGNEAVLLHNTAMVEDWLVI"
     CDS             507..1067
                     /locus_tag="ctg233_2"
                     /transl_table=11
                     /translation="MGNKNTGDPQLLDHILQPASKLRTDFCIDRRKRLIQKEKLRIRSQ
                     SPGKSNSLSLTTGQLTRISFLQTLQPDQLYQFHNPLLNILLVRRLYLQAKCNIIIHRHI
                     PEKSIILEHKSNASLAGRHIIDHSSVDDDFTAVRLLQTGDHTENRSFSASAGPQKTDQL
                     PLFDTKAYVIRCLVIPICFIDIF"
     CDS             1352..1591
                     /locus_tag="ctg233_3"
                     /transl_table=11
                     /translation="VDNKRRSQLVKYLQGYGFRVQKSCFEVILNKSVFKKLKMEIAQYA
                     TDEDSIRIYQLHGIGQVTCYGNNFLVVPRDIIIV"
     CDS             1769..2080
                     /locus_tag="ctg233_4"
                     /transl_table=11
                     /translation="MLDIIQADVLALGEYTQAVYSMEFSSAIIREKYEGEKVRDALEKN
                     DQDRHNAHERAIMGVKRLNRFAEMKGLEPIFDGDVSNRYEVADFCCETVKEYFDNRIL"
     CDS             complement(2152..2601)
                     /locus_tag="ctg233_5"
                     /transl_table=11
                     /translation="MGLIAISSLMLLGGMYLMIAFAWWLLQIIANWRIFTKAGEAGWKS
                     IIPIYGDYISYKIAWQPAYFWLTLVLGIVSSCLQGTLETNDSLMISMIIVLIKIILAII
                     SIMYSVKLARAFGRSTGFAIGLIFLQPIFMLILGFGDDRYYGANK"
     CDS             3369..3638
                     /locus_tag="ctg233_6"
                     /transl_table=11
                     /translation="MIPVIYYEDITAILMNYKIPGYYIFFICLAVISCFSNPGMIICVL
                     LFIWAGSNYKITICLRSGNKAVVYSNRKKIATAFVEDIKERAKI"
     CDS             3676..4260
                     /locus_tag="ctg233_7"
                     /transl_table=11
                     /translation="MAAKTIMKRIAIAALSAVILQGVTPLDSLNVYASENTGASYTALD
                     LYTYMQDQCSTEYTLTEKAETFLEEHDDFFPASPELVIPDEMIDAELDFRHINKNPSRY
                     GDKLMRISDAYVIQVQEQEMEEGHYLTWLNLIDGEEQQYSVYYNGELDDVFEDDTVEVT
                     GLPLGTSSFENTEGGDTLVVVLAGCRVNNID"
     CDS             4511..4894
                     /locus_tag="ctg233_8"
                     /transl_table=11
                     /translation="MKITEELLNEMKIKDENFSDGLIKPDGDYVRIPRGHLHGMMELLP
                     WTENEIWKMIPDDDSPLFWLIEKTGCVLTDYNNSIGMKMTPAQQTVFDMMRKHGVLTDD
                     YYDLTKQREKVREAREQKENRKQ"
     CDS             5278..7803
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: Gly_radical"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: PFL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg233_9"
                     /sec_met_domain="Gly_radical (E-value: 5.6e-36, bitscore:
                     114.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL-like (E-value: 4.5e-264, bitscore:
                     868.6, seeds: 123, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKFQTSDIPKSPRIQKLVDALYEHMPVIESARAKLITESYKETE
                     GEPIITRRAKAFAHILHNIPIIIRDNELIVGSSTIAPRGCQTFPEFSYEWLEAELDTVA
                     TRTADPFEIAEETKAELKEADKYWKGKTTSELATSYMAPEAIKAIEHNIFTPGNYFYNG
                     VGHVTVKYWEVLEIGFEGIMEKAQKELDGCSVGDGNYARKSHFLEAVILSCKAVIDYAG
                     RYAKLAQEMAAQTSDPVRKQELFVIAENCSRVPAKGAQNFYEACQSFWFVQQLLQMESS
                     GHSISPGRFDQYMYPYYKKDMEAGTITREFAQELMDCIWVKLNDLNKCRDAASAEGFAG
                     YSLFQNLIAGGQNKEGEDVTNDLSVMCIQASMHVHLPAPSLSVRVWNGSPHEFLIKAAE
                     LTRTGIGLPAYYNDEVIIPALQNRGLSLEDAREYNIIGCVEPQKAGKTEGWHDAAFFNM
                     CRPLELVFSNGMDKGEMVGIPTGDVTQMKTFDEFFDAYKKQMEYCISLLVNADNAIDVA
                     HAERCPLPFLSCMIDDCLKEGKSVQEGGAVYNFTGPQGFGIANMADGLFAIRKLVYEDK
                     KVSMKELKEALAWNYDKGLDAQSAGDMTEMIMKAMQKAGRNVDASTAEGLLKTFMGMKP
                     GEQKTQRFKEIHDMIDEVPKFGNDIPEVDYFAREVAYTYSKPLQKYNNPRGGKFQAGLY
                     PVSANVPLGGQTGATPDGRYAHTPVADGVSPSAGKDVKGPTAAATSVSRLDHFIVSNGT
                     LFNQKFHPSALSGREGLEKFVALIRGYFDQKGMHMQFNVVDRQTLLDAQEHPEKYKHLV
                     VRVAGYSALFTTLSRSLQDDIIRRTEQGF"
     CDS             7885..8667
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg233_10"
                     /sec_met_domain="Radical_SAM (E-value: 3.5e-28, bitscore:
                     89.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDTKGRVFDVQKYSIHDGPGIRTIVFLKGCVLRCKWCCNPESQEY
                     KIQTMKVQGEDKVIGRDVTVREMIEEVEKDRVYYYRSGGGMTLSGGECLCQPEFAGALL
                     RAAKERGISTAIESMACAKWETIETILPYLDTYLMDIKHTNPAKHKEFTGRSNELMMEN
                     ARKVALSGKTRLVIRVPVIPTFNDTVEEIQGIARFADTLPGVDKIHLLPYHRLGQDKYE
                     GLGRPYLMGNVEPPSKEHMETLKKAVHAVCGLDCQIGG"
     CDS             8846..9721
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldolase_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg233_11"
                     /sec_met_domain="Aldolase_II (E-value: 1.1e-46, bitscore:
                     149.9, seeds: 389, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMVNEYEIKKQICDIGRRIYSRNMVAANDGNISVKLNDNEFLCT
                     PTGVSKGFMTPEYICKVDREGNVIQANPGFKPSSEIKMHMRVYEKRPDVGSVVHAHPIY
                     ATSFAIAGIPLTQPIMPEAVISLGCVPIAEYGTPSTMEIPDNLEKYLPYFDAVLLENHG
                     ALTWSTDLNAAYMKMESVEFYAQLLYQSKVLGGPKEFDEKNIKKLYEIRRKFGMAGKHP
                     ANLCLNKDGHNCHNCGGACHDGEFKKFPGYQYDFVGGGDSQPAAGTADKSEAELVAEIT
                     KQVMAQLGMK"
     CDS             9758..11146
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: Aldedh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg233_12"
                     /sec_met_domain="Aldedh (E-value: 5.8e-37, bitscore: 117.9,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPINENMVQEIVQEVMAKMQIADAPTGKHGIFKEMNDAIEAAKKS
                     QLIVKKMSMDQREKIITCIRKKIKENAEVMARMGVEETGMGNVGDKILKHHLVADKTPG
                     TEVITTTAWSGDRGLTLIEMGPFGVIGAITPCTNPSETILCNTMGMLAGGNTVVFNPHP
                     AAIKTSIYAINLLNEASLECGGPDNIAVTVEKPTLETSNVMMKHKDIPLIAATGGPGVV
                     TAVLSSGKRGIGAGAGNPPALVDETADVRKAATDIVNGCTFDNNLPCIAEKEIVAVSSI
                     VDELMHYLVTENDCYLASKEEQDKLTEVVLAGGKLNRKCVGRDARTLLSMIGVNVPANI
                     RCIVFEGPKEHPLITTELMMPILGVVRARDFDDAVEQAVWLEHGNRHSAHIHSKNIDNI
                     TKYAKAIDTAILVKNAPSYAALGFGGEGYCTFTIASRTGEGLTCASTFTKRRRCVMADS
                     LCIR"
     CDS             11172..12389
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg233_13"
                     /sec_met_domain="ADH_N (E-value: 2.1e-17, bitscore: 53.8,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.7e-23, bitscore:
                     71.9, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMNNVNIEEIVKQVLSGMTGNAPAAASAPAASTGIPKTARVAVL
                     TEKEHFDIKEYPIPPIGDDDILVKVEGCGVCGTDAHEFKRDPFNLIPVALGHEGTGEIV
                     AMGKNVKVDTAGKPVKVGDKVVTCMIFKDDPDITMFDLNKKNVGGADVYGLLPDDDVHL
                     NGWFSDYIFLRGGNFGTTFFNVSDLDLDSRILIEPCAVLVHAVERAKTTGILRFNSRVV
                     VQGCGPIGLICIAVLRTMGVEHICAVDGNEKRLEFAKRMGADTSVNFMNFKGIEALTEA
                     VKEAQGGHLADFAFQCTGNPKAHANIYKFIRNGGGLCELGFFINGGDATINPHFDLCSK
                     EINLVGSWVYTLRDYVTTFDFLKRAKAIGLPMSELITDKFPLEQINEALQTNLAMTGLK
                     IAVVNK"
     CDS             12485..12799
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 75.8; E-value:
                     6.6e-24)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg233_14"
                     /sec_met_domain="BMC (E-value: 2.8e-24, bitscore: 75.8,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAVGILEVFGLATAFVAGDAGCKAANVRLEVFDKNKPANADSL
                     PVPLLVCIKFRGSVTDVTAAVEAGMEVANRMTGVVQHYVIPNPEEGTEKMLKISALDKD
                     "
     CDS             12872..13147
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 100.7; E-value:
                     1.1e-31)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg233_15"
                     /sec_met_domain="BMC (E-value: 4.6e-32, bitscore: 100.7,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQEALGMVETRGLTAAIEAADAMTKAAEVALVGTEKIGSGLVTV
                     MVRGDVGAVKAAVESGSAAASRLGELVATHVIPRPHTDVEKILPSI"
     CDS             13184..13486
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 78.4; E-value:
                     1e-24)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg233_16"
                     /sec_met_domain="BMC (E-value: 4.2e-25, bitscore: 78.4,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKSYGFIEITGVVAAIDALDIMCKTADVELASWERKLGGRLVTI
                     IVEGDVSAVTEAVNAAATGAIKKPVSYAVIARPHEEIVRMVELSASRWKNNQGDE"
     CDS             13486..13962
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 100.4; E-value:
                     1.4e-31)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg233_17"
                     /sec_met_domain="BMC (E-value: 5.7e-32, bitscore: 100.4,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEKKPEADKNAPKKAAAPRRTKAKTSSKPEVKAQTADTAAETA
                     NKTESQKEQIKETVSHKEEKVMTQEALGMVETRGLTAAIEAADQMCKAANVALVGTEKI
                     GSGLVTVMVRGDVGAVKSAVESGSAAASRLGELVATHVIPRPHTDVEKILPVLK"
     CDS             14048..14692
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: PTAC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg233_18"
                     /sec_met_domain="PTAC (E-value: 1.5e-29, bitscore: 92.9,
                     seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LESNNIELITRMVIQAINQNEKKGDGFMVPIGVSARHIHLTQEHV
                     EALFGPGYQLTKKKELMGGQFASNETVTIVGLKLRAIENVRILGPVRKASQVEVSATDA
                     IKLGMNVPVRESGDVAGSAPIAIVGPKGAVYLKEGCIVAMRHIHMSPKDAQAAGVKDGD
                     IVSVKADNERGTIFNQVKIRVDDSFTLEMHIDTDEANAAKIATGTTVTIIK"
     CDS             14768..15091
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: EutN_CcmL"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg233_19"
                     /sec_met_domain="EutN_CcmL (E-value: 1.9e-31, bitscore:
                     99.4, seeds: 194, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGAEVFAPNIIIRNNLEAHMIVGKVVGSVVSTRKSEKLIGSKFMI
                     IEPVHHMKGDLSQLVAIDMIGAGVGEYVLVAQGSAARIGCGVETAPVDAAIVGIIDDGA
                     GLE"
     CDS             15096..16424
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RnfC_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg233_20"
                     /sec_met_domain="Fer4_17 (E-value: 6.9e-12, bitscore: 36.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 9.7e-09, bitscore: 25.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.4e-42, bitscore:
                     136.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.4e-20, bitscore: 63.3,
                     seeds: 53, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKELQDIIQQNGVVGAGGAGFPTYMKLTDKANTILMNCAECEP
                     LLKLHRQLLEKHAYEIMKTFHMIQETVGASEAIIGIKKSYVQTIHALNQHIEEFPGMRL
                     HLLDEVYPMGDEVVLIYEATGRVVRPGGLPIEQGVAVFNVETVYNVYRAVEEKQPVTDK
                     YVSVVAEVSDPVTVRVPLGCTLEEVVAQAGSTTVKDPVYFVGGPMMGRIGNGSDPVTKT
                     TNAILVLPKDHLIVAKKQRTSSIDLKRAASICCQCNTCTDLCPRHNLGHPIDPAKFMRA
                     ASNNDFRDLNPYIDASFCSSCGVCEMYSCPQSLAPRSLLADMKGGLRKAGIRPPQGVQP
                     KPVQESREYRKVPEERLMARLGLTRYDKDAPLKEELVQVKKVRILLSQHIGAPAQAVVK
                     AGDEVTRGQMIAQPAQGLSVGIHASVSGKVTEVTDRYIIIAVK"
     CDS             16441..16989
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 69.1; E-value:
                     8.4e-22)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg233_21"
                     /sec_met_domain="BMC (E-value: 3.4e-26, bitscore: 81.9,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKAIGMIEFKTTSTGVTAADAMVKTSEVEIVEAQTVCPGKYIAI
                     ITGDLSAVKAAVDTAVTTYEDKCIDSFVLGNPHESIFPAIYGTTQVEDISALGILETYD
                     AASIIEAADQAAKTAIVDLIELRIAKGMCGKSYMMITGEVSAVEASIDRAKELVAAKGM
                     YLDSSVIAHPDRRMIDSIL"
     CDS             17057..17821
                     /locus_tag="ctg233_22"
                     /transl_table=11
                     /translation="MLALERRNLILEKLQAEKRVVVSELSQLYDVSEETIRRDLDKLEK
                     EGLAIKSYGGAVINEDVSIDLPFNVRKNQNVTGKQKMAELAASLVKDGDHIFLDASTTA
                     VFVAKALKEKERLTVITNSMEILLELADVSGWNIISTGGVMKEGYLAFLGSKTDESIRS
                     YYVDKVIFSCKALDLEWGIMESQEAFGSTKRAMIGSGRKKILVVDSSKFDQTAFSVAGS
                     MKEVDIIVTDKEPTERWKKHFEKFNVKCLYPV"
     CDS             17846..18997
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     358.3; E-value: 1.3e-109)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg233_23"
                     /sec_met_domain="Fe-ADH (E-value: 5.4e-110, bitscore:
                     358.3, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTFEMKTAIHFGDNALDRLKEIPYKRVLIITDPFVVQSKMIDLI
                     TAPLNSAGIEYDIFHDVVPDAPVDKIAEGVKKFLEYQPEAVVAVGGGSAIDSSKAIREF
                     ALKINNYGKVGLIAIPTTSGTGSEVTSFAVVNDTAAHVKYPLISESLTADEAILDAELV
                     RSVPPAITADTGMDVFTHALESYVSTAHNEFSSALAEKAIEICGVFLLRAYLDGSDMHA
                     RKKMHVASCLAGLSFNTAGLGITHSMAHQLGAMFHIPHGRANAMLLPHIVEFNSDINKH
                     SKSQKEYLPAVKRYANVAHILGLSNYNKVMTVRSLVNWIQFMQKEMNIPLTIQELGTIA
                     PEEYFAAIDKMADAALADACTVNNPRVPTKEDIIKIYTKLWSF"
     CDS             19066..20148
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cob_adeno_trans"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg233_24"
                     /sec_met_domain="Cob_adeno_trans (E-value: 1e-40, bitscore:
                     130.4, seeds: 584, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIYTKRGDRGITDMAHAGNISKSDDRIRLMGEADELNSHIELVK
                     SMLRQSEILQLLERIQKNLDLIAAGVSNPYDRDCKVSEKETAVLEAETDKLEALCEKPV
                     PEKLTGKSRLAAEIDIARTVARRTERCLAQVSVKFGADTESKRFLNRLSDYLYILARYI
                     EYYSDLSVELSDDHAGALAKTSDNNTDALPEPSDSNTDVLKKTADINEAVIQEVLKRMG
                     IQSRITLDTAKKLIERLEQEAVRRGQRAVIAVCNPEGNPVAVHVMDGAFLVSFDVAMKK
                     AYTAVAVKMSTMELSKIAQPGGTFYGVDKLDGGKIVIFGGGIPLKSGNTIIGGLGISGG
                     TGEEDHSLAEYGQSVLNEIL"
     CDS             complement(20268..21020)
                     /locus_tag="ctg233_25"
                     /transl_table=11
                     /translation="MSYHWHVEYEIIRILEGSLTVTLDEKSFTAVKNDVIFVHSGILHS
                     GIPHDCVYQCIVFDMNTFLKNNPVCGEYIQKILHQETMLFPHFSDEHPQILNCISVLFN
                     AMYEKDTGYELTVFGQFYHFFGLVFSNHYFIENPTRTRRDYKRILQLKQVLEFIEKNYA
                     NPITLQELSASVSMSPKYFCRFFSEMTHQTPVDYLNRQRIEEACLQLAATDDSITEIAY
                     RNGFNDLSYFIRTFKKYKGMTPGKYKRR"
     CDS             21379..21549
                     /locus_tag="ctg233_26"
                     /transl_table=11
                     /translation="LGVRACLKNHSRNLHAPLCGIFHPNSVAVARYGALIRAKYPTNCD
                     AHLAESLFQTRS"
ORIGIN
        1 gccgctcccg cggcattttt ttatatcact aaccaatcct caaccatagc tgtattatgc
       61 agcagtactg cctcatttcc cttcgttaca aaaatcctct gcacaaacac atccacaact
      121 tcgccttccc ggacgggttc ttcgtcaagg cttcttctgg cgctgagtgt ggcgtttcct
      181 acacggactt tcagttccag gctgctgccg cggaatgcga ctcgttctac gatgccctct
      241 gttgcggagc ttttatattt ctgctcctcg ttcttctttg tcacttttac aaactccgga
      301 cggacaatgg ctttttcgcc tcctggaact tccttgaagt gattgaacac ctggtaatca
      361 tcgatcacag aagtctgccc gaaaaatccc gccgtaaacg cagtatccgg attctgataa
      421 acctccagtg gagttccctt ctgctcgatc cgtccacggt tggtaataat aatttcatcc
      481 gccacctcaa tagcctcatc ctggtcatgg gtaacaaaaa tactggtgat ccccagcttc
      541 tcgatcatat ccttcagcca gcttcgaagc tccgtacgga tttttgcatc gatcgccgca
      601 aaaggctcat ccagaaggag aagctgcgga ttcggagcca gagcccgggc aaaagcaact
      661 cgctgtctct gaccaccgga cagctgactc ggatatcttt tctccagacc cttcagcccg
      721 atcagctcta ccagttccat aaccctctgc ttaatatact tcttgtccgc cgtctgtacc
      781 ttcaggccaa atgcaatatt atcatacacc gtcatatacc ggaaaagagc ataattctgg
      841 aacacaaatc caatgcctcg ctcgctggca ggcacatcat tgaccactct tccgtcgatg
      901 atgatttcac cgctgtccgg ctgctccaga ccggcgatca tacggagaat cgtagttttt
      961 ccgcttccgc tgggccccag aagaccgatc agcttcccct tttcgatacc aaagcttacg
     1021 ttatcagatg ccttgtaatc cccatatgtt ttattgatat tttttaactc aacgtacatc
     1081 gcctttttcc gagttaggcg agaaaatgat cgtcaatgcc ggtggtgaca tctaatgaga
     1141 acatcccaag ataacggaaa gtggtgttga atcaccactc ctaccacatc taatgagaac
     1201 attccaagat aaaaaccaga aaatgtcacc ctgttttaag gagggtaatc ctgttttaat
     1261 aaggtgagtt ggatgatatg gaagaaatag aatttacaac acccgatgaa aaaaatcaaa
     1321 tgaagtattt gcgttaataa tatacgatat tgtggataat aaacggagaa gtcaactggt
     1381 caaatatctt cagggatatg gttttagagt acagaaatca tgttttgaag taatattgaa
     1441 taaatcagtg ttcaaaaaat tgaagatgga gattgcccaa tatgctacag atgaggacag
     1501 tatccgaata tatcagcttc atggtattgg acaagtgaca tgttatggta ataattttct
     1561 ggttgtgcca cgagatatca ttatagtata atgctttgta taagatatta tatcgtaaga
     1621 agtgattatt gaaaaaacaa gctattaata tagccgtact gctttgtgat tatgatataa
     1681 acaatgttaa gttgatagcg ggaggagtta gagaataatt aaagaaaaaa tcaacagatt
     1741 aattgatgca tgcaaagatg attctgatat gctggatatt atccaggcag atgtgctggc
     1801 tttgggagaa tatacacagg cagtatattc aatggaattt tccagtgcaa ttatccggga
     1861 aaaatacgag ggtgagaaag tcagagatgc tctggagaaa aatgatcagg acagacataa
     1921 tgctcatgaa cgtgccatta tgggagtgaa acgtttgaat cgttttgcgg aaatgaaggg
     1981 acttgaaccg atttttgacg gagatgtgag taacaggtat gaggtggctg atttttgctg
     2041 tgaaacggta aaagaatatt ttgacaacag aattctataa taaactgtaa tctgtatata
     2101 tgtaaaaatc ctcggaacgt aagttccggg gattttccat ttaatatata cttatttatt
     2161 tgccccataa tatctgtcat cgccgaagcc aaggatcagc atgaagattg gctgtaagaa
     2221 aataaggcca atggcgaatc ctgtgcttct gccaaaagct cttgcaagct taacactgta
     2281 cataatgctg attatggcaa gtatgatttt gatcagtacg atgatcatgg agatcattaa
     2341 actgtcgttt gtttcaagag ttccctgtaa gcaggaagat acgattccaa gaaccaatgt
     2401 cagccagaaa tatgcaggtt gccatgcgat tttataagaa atataatcgc catatattgg
     2461 aataatactt ttccatccgg cctcccctgc tttggtaaag attctccagt tggcaatgat
     2521 ctgcagaagc caccatgcga atgcgatcat cagatacata ccgcccaaga gcatcagact
     2581 gctgatagct ataagaccca tttgtgttcc tccatttctt tttgtgagat atgatacaat
     2641 gtatcattgg tgtagatgcg tagttgagaa ctatgtttgt tctcctgaag tatttatact
     2701 aaatccatta aagcatattc tcaggagttc gtcaattatc aaagaagatt gtaaatttta
     2761 tatttgatag ttggctacgt tactgtaagg aacaaaaata acgtttggcc ataagtgaga
     2821 aaactattgt tgctgtggcg taaaacatat actgtcagtg aatgaaaagc tgataagaga
     2881 agggtataat gagtgtaata aagatgagtg aattataaca atcctctaaa tgaattactg
     2941 aagattgtac ataagtgagg tgaaaactat ggcagcaata cttatgatcg cttacatagc
     3001 ggcagcatat tgggcgacta ataagatatg gtggtctaag aaagtgtatg tttattccaa
     3061 tgcaacatac ttctacatga cacgttttat tatctgtatg gttgcaggat ttgtgacaat
     3121 acccattgca ctgctgctga cattggtcgg taaaaactga aataagaggg gaaagtaata
     3181 tggaagcact ggaaactcaa acacaggcta cacaggaaaa agaaaatgct gtgacaaagc
     3241 agaatatgaa gtataccatg agttcttcaa gaggaattta tttatcgtgg ctgacgggaa
     3301 ggatttacag cacaattctt gctgatcacg aaaagctgac tatagatata aagccggtaa
     3361 agaagaatat gattcctgtg atctattatg aagatattac ggcaatactt atgaactaca
     3421 aaataccagg atattatata tttttcattt gtctggcagt gatttcctgt ttttctaatc
     3481 ctggaatgat catatgtgtt cttctgttta tatgggcagg ctcaaattat aaaataacga
     3541 tatgtctgag aagcgggaac aaagcggttg tatattccaa cagaaagaaa atagctacag
     3601 catttgtaga ggatattaaa gaaagagcga agatataatt aatggtaaat gttacaaaag
     3661 aaaaggggga taactatggc agcaaaaaca attatgaaaa ggatcgcaat agcagcatta
     3721 tcggcggtta ttttacaggg agtaacacct ctggacagtt taaatgtata tgcctcagag
     3781 aatacaggtg caagctatac agcactggat ttgtatacat atatgcagga tcaatgcagt
     3841 acagagtata cattaacgga gaaggcggaa acttttctgg aagaacatga tgattttttc
     3901 cctgcttcac cagaactggt aataccggat gaaatgatag atgcagaact ggattttcgc
     3961 catatcaaca aaaatccatc cagatatggt gataagctga tgagaatttc ggatgcatac
     4021 gtaatacagg ttcaggaaca ggaaatggaa gaaggacatt atctgacatg gctaaatctg
     4081 atagatggag aagaacagca gtattctgtt tattataatg gagaattgga tgatgttttc
     4141 gaggatgata cagtagaagt aaccggtctg ccgcttggaa ccagttcatt tgagaatacc
     4201 gagggtggag acacgcttgt tgttgtatta gcgggctgta gggttaacaa tattgattaa
     4261 atgggttact gttcactggt aatatcccgc gaggtgtttt ttgtgagcga aggtcacaga
     4321 aaacccgaga tataccgcgc gaatttatgc gattagcata aattctgtgc atcgcgaagc
     4381 gtgttactga gaacggagtg aacagtaaca tatattttga ggaaagaggc tattcagact
     4441 ttttacttgc gtaactctgg cgggaaacgt ataataggaa aaagcaatac tcgagggtga
     4501 ggaaaagagg atgaagataa cagaagaact gttaaatgag atgaaaatta aggatgagaa
     4561 cttttctgac ggtctgatca agccggacgg cgattacgta agaataccca gaggacatct
     4621 tcatggaatg atggaattgc ttccatggac agagaacgaa atctggaaaa tgattccgga
     4681 tgatgattct ccgctgttct ggctgattga gaaaacagga tgcgttctta cggattataa
     4741 taattctatt ggcatgaaga tgacacctgc tcagcagact gtgtttgata tgatgcgaaa
     4801 acatggggtt cttacagatg attattacga tctgacgaaa cagagggaga aagtaagaga
     4861 agccagagaa caaaaagaga acaggaaaca atagttaagt gtatatgaat atatgggagt
     4921 gcagcgatgg aaaagcatgc tcattaaagt catccgatgc agaaaaaaca atatacgata
     4981 ttaaaaagca gcatatcaga gttatggatc ataacctgat atgctgcttt taacgtgtct
     5041 gaagaaaaat gaaatgtcaa tcataaaaac aaaacaaaaa caaccagaac ggaagaaaaa
     5101 acaaataaaa aacaacatga aagttcagaa tatgcatgtt gatttatgtt gacttcgcgt
     5161 tagccataag gtataatgaa tctatatgaa aacatggagg atattgctgt cagaatgata
     5221 ccggaatgta ttggggtctg gtatgggtgc agcttttatt catgagaaag gagtaacatg
     5281 gaaaaatttc aaacatcaga tattcccaag tctcccagaa ttcagaaact ggtagatgca
     5341 ttgtatgaac atatgccggt gatcgaatca gccagagcaa agctgatcac agaatcttat
     5401 aaggaaacag aaggagaacc gatcatcaca cgcagagcaa aggcttttgc gcatattctt
     5461 cataatattc cgatcattat ccgtgacaat gaactgattg tcggaagcag tacgattgcg
     5521 ccgaggggat gtcagacatt tccggagttc tcttatgagt ggctggaagc tgaactggat
     5581 acagttgcga ccagaactgc ggatcctttt gagattgctg aggagaccaa agccgaactt
     5641 aaggaggcag ataagtactg gaaagggaaa acaaccagtg aacttgcaac ttcctatatg
     5701 gcaccggaag caatcaaggc aattgaacac aatattttta cacctggaaa ttatttttac
     5761 aatggtgtag gacatgtaac agttaaatac tgggaagtac tggaaatcgg ttttgaggga
     5821 atcatggaga aggctcagaa agagctggat ggatgcagtg tcggtgacgg taattatgca
     5881 agaaagtctc acttccttga ggcagtgatt ttaagctgta aggcggtgat cgattatgca
     5941 ggcagatatg caaaacttgc gcaggaaatg gcggcacaga caagtgatcc ggtaagaaaa
     6001 caggaacttt ttgttatcgc agagaactgc agcagggtac cggcaaaggg tgcacagaat
     6061 ttctatgagg catgtcagtc attctggttt gtacagcagc ttcttcagat ggaatccagt
     6121 ggacattcta tttcaccggg gcgctttgat cagtatatgt atccatatta taagaaggat
     6181 atggaagcag gaactattac ccgagagttc gcacaggaat tgatggattg catctgggtt
     6241 aaattaaatg acctgaataa atgtcgtgat gcggcttcag cggaaggatt tgcaggatat
     6301 agccttttcc agaatctgat cgcgggtggt cagaataaag agggagagga tgtaactaac
     6361 gatctttctg ttatgtgtat tcaggcatcc atgcatgtgc atcttccggc tccatcactt
     6421 tctgtgagag tgtggaatgg ttctccgcat gaattcctga taaaggcagc cgagcttacg
     6481 agaacaggaa tcggacttcc tgcatattac aatgatgagg tgattattcc ggcactgcag
     6541 aacagaggct tatctctgga ggatgccaga gagtacaata tcatcggatg tgtggaaccg
     6601 cagaaagccg gtaagacaga aggatggcat gatgccgcat tctttaatat gtgcagacct
     6661 ctggaacttg ttttttcgaa tggtatggat aaaggtgaga tggtgggaat ccctaccggc
     6721 gatgtcactc agatgaagac ctttgatgaa ttctttgacg catataagaa acagatggaa
     6781 tactgcattt ccctgctggt gaatgcagat aatgctattg atgtagctca tgcggaacgc
     6841 tgtccgttac cattcctttc ctgtatgata gatgactgtc tgaaagaagg caagtctgtc
     6901 caggaaggtg gagctgttta caactttaca ggtcctcagg gatttggaat cgccaatatg
     6961 gcagatggac tttttgcaat ccgcaaactg gtctatgagg ataagaaagt atctatgaaa
     7021 gaacttaagg aagctcttgc atggaactat gataaaggac tggatgcgca gtccgccggt
     7081 gatatgacag agatgatcat gaaggcaatg cagaaagcag gcagaaatgt ggatgcttcc
     7141 actgcagaag gacttctgaa aactttcatg ggaatgaaac cgggtgaaca gaagacacag
     7201 agattcaaag aaatacacga tatgatcgat gaagttccga aatttggaaa tgatattccg
     7261 gaagttgatt attttgcaag agaagttgcc tatacatatt ccaaaccgct tcagaagtat
     7321 aacaatccaa gaggcggaaa gttccaggca ggtctgtatc ctgtatctgc aaatgtaccg
     7381 ctgggcggac agacaggagc gacgccggat ggaagatatg cacacacacc tgttgcagac
     7441 ggcgtttcgc catctgcggg caaggatgta aagggaccta cggcagcggc aacttccgta
     7501 tccagactgg atcattttat tgtatccaac ggaacgcttt ttaaccagaa attccatcca
     7561 tccgcacttt ccggaagaga gggactggag aaatttgttg cactgatccg tggatacttt
     7621 gaccagaagg gaatgcacat gcagtttaat gtagttgaca ggcagacact gctggatgca
     7681 caggaacatc ctgagaaata taaacatctg gtagtacgcg tggcaggcta cagtgcactg
     7741 tttacgacac tttcccgttc ccttcaggat gatatcatcc gtcgtacaga acagggcttc
     7801 tgattcagac gtttttgcag gaagtaaaag tgacaggcag agtatgtatg gataacagaa
     7861 taagaaagga aaagcatgga ctatttggat acaaagggca gagtgtttga tgtccagaaa
     7921 tattctattc atgatggacc gggtataagg acgatcgtat ttctgaaagg ttgtgtcctg
     7981 cggtgcaaat ggtgctgcaa tccggaatct caggaatata agatccagac aatgaaagtg
     8041 cagggagaag acaaggtcat cggacgtgat gtgacagtca gggagatgat tgaagaagtt
     8101 gagaaagaca gggtatacta ttaccgctcg ggcggaggta tgactctttc cggcggagaa
     8161 tgtctctgtc agccggaatt tgcaggagca cttctgagag ctgccaaaga gagagggatt
     8221 tctactgcga tcgagagtat ggcatgtgca aaatgggaga cgattgagac aatcttaccg
     8281 tatctggata cttatttaat ggatattaaa catacaaatc ctgcgaaaca taaagaattt
     8341 acaggacgtt ccaatgaact gatgatggaa aatgccagaa aagtggcgct ttccggtaaa
     8401 accaggctgg taatccgtgt accggtgata cccacattta atgatacagt ggaggaaatc
     8461 caggggattg caaggtttgc agacacactt cccggagtgg acaagattca tcttcttccg
     8521 tatcacagac ttggacagga taaatatgag ggacttggca gaccatatct gatgggaaat
     8581 gtggaaccac cgtccaaaga acatatggaa acattaaaaa aggcagtaca tgcggtctgc
     8641 ggtctggact gtcagatcgg tggatgaggc attttttgca tctgatacga ttattggaat
     8701 aaaaaaagaa aaaacaaata aaaacaacac aataaaacct gtgaaaacaa cataaaacaa
     8761 cggaaatgta ttgacttttt atgaccgata gtgtaaaatc acaggtagaa acgtcaaaaa
     8821 ctatataaat gccttaagga ggaaaatgag catggtaaac gaatatgaaa tcaaaaaaca
     8881 gatctgcgac atcggaagaa gaatctacag ccgcaacatg gtagctgcaa acgatggtaa
     8941 catctctgta aaactgaacg acaacgaatt tctttgcaca cctacaggtg tatctaaagg
     9001 ttttatgaca ccggagtata tctgtaaagt agacagagaa ggaaatgtga tccaggctaa
     9061 cccgggattc aaaccatcct ctgaaatcaa aatgcatatg agagtttatg agaagagacc
     9121 ggacgtaggt tctgttgtgc atgctcatcc gatttatgca acatcttttg caattgcagg
     9181 tattccgctg acacagccga tcatgcctga agcagttatc tcacttggat gcgttccgat
     9241 cgctgaatac ggtacaccat ctacaatgga gattccggat aatcttgaga aataccttcc
     9301 atatttcgat gcagttcttc ttgagaacca tggagcactg acatggagca cagacttaaa
     9361 cgcagcttac atgaagatgg aatctgttga gttctacgca cagcttctgt atcagtcaaa
     9421 agttcttggc ggacctaagg aatttgatga gaagaacatt aagaaactgt atgaaatccg
     9481 ccgtaaattc ggtatggcag gcaagcatcc tgcaaacctc tgcctgaata aagatggcca
     9541 taactgccat aactgcggcg gcgcatgtca tgacggcgaa ttcaagaaat tccctggata
     9601 tcagtatgat ttcgtaggcg gcggagattc ccagccggca gcaggaacag cagacaaatc
     9661 tgaagctgaa ttagttgctg agatcacaaa acaggtaatg gctcagttag gaatgaaata
     9721 agagtataga tgaccgataa tcaaggagga cagtctcatg ccaattaatg agaatatggt
     9781 acaggaaatt gtacaggaag taatggcaaa aatgcagatt gcagacgctc cgactggtaa
     9841 acatggtatt ttcaaagaaa tgaatgatgc gatcgaagca gcgaagaaat cgcagcttat
     9901 cgtaaagaag atgtccatgg atcagagaga aaaaataatt acctgcatcc gtaagaaaat
     9961 aaaagaaaac gcagaagtaa tggctcgtat gggcgtggag gaaacaggta tgggaaatgt
    10021 tggggacaag atcctcaaac atcatcttgt agctgacaag actcccggaa cagaagttat
    10081 tacaacaact gcatggtccg gagacagagg attaaccctt atcgagatgg gaccttttgg
    10141 tgtgatcggt gcgatcactc catgtaccaa cccaagtgaa acaattttat gtaatacaat
    10201 gggaatgctt gcaggaggaa atacagttgt attcaatcct catcctgcag cgatcaaaac
    10261 ttccatttat gcaatcaatc ttttaaatga agcatcatta gagtgcggtg gtcctgacaa
    10321 cattgcagtt actgtagaga aacctacact tgagacaagc aatgtgatga tgaaacataa
    10381 agacatcccg cttatcgctg caaccggcgg acctggagtt gtaactgcag ttctttcttc
    10441 cggtaaacgt ggtatcggag caggcgccgg aaatcctccg gcactggttg atgaaaccgc
    10501 tgatgtccgc aaagcagcca cagatattgt aaacggatgt acatttgata ataatcttcc
    10561 atgtattgcc gagaaagaga tcgtagcagt ttcctctatc gtagatgagc tgatgcacta
    10621 tcttgtaact gagaatgact gctatcttgc ttctaaggaa gagcaggaca aacttacaga
    10681 agttgttctg gcaggcggaa agctgaaccg taaatgcgta ggccgggatg caagaacact
    10741 cctttccatg atcggagtaa atgtacctgc aaatatccgc tgtatcgtat ttgaggggcc
    10801 aaaggaacac cctctgatca ctactgagct gatgatgccg atcctcggtg ttgtaagagc
    10861 aagagatttt gatgatgcag tagagcaggc agtctggtta gaacatggca atcgtcattc
    10921 cgcacatatt cattcaaaga atattgataa tatcacaaaa tatgcgaaag caattgatac
    10981 agcaattctt gttaagaatg caccgtctta tgcagctttg ggatttggcg gtgaaggcta
    11041 ctgtacattt accattgcaa gccgtacagg tgaaggcctt acatgcgcaa gcacattcac
    11101 caagagaaga cgctgcgtaa tggcagacag tctctgtatt cgataagaat tgatataagg
    11161 agagaaagaa catggacatg aataatgtaa atatagaaga aatcgtgaaa caggttctct
    11221 ccggcatgac aggaaatgca ccggcagcag cttctgcacc ggcagcatca actggaatcc
    11281 cgaagacagc cagagtagct gtattaactg agaaagagca ttttgacatc aaagaatatc
    11341 caatcccgcc aatcggagat gatgatatcc tggttaaagt tgaaggatgc ggcgtatgcg
    11401 gtacagatgc acacgaattt aagagagatc cgtttaacct gatcccggta gcacttggac
    11461 atgaaggtac aggtgagatc gtggcaatgg gtaagaatgt taaagttgac acagcaggaa
    11521 aacctgtaaa ggttggagac aaagttgtta cctgtatgat cttcaaggat gatcctgata
    11581 ttacaatgtt tgacctgaac aagaagaacg taggcggagc tgatgtatac ggacttcttc
    11641 ctgacgatga tgtacatctc aacggatggt tctctgatta catcttctta agaggcggaa
    11701 acttcggaac tacattcttt aatgtaagtg atctggatct ggattcccga attctcattg
    11761 agccatgtgc agtgcttgta catgcagtag agagagcaaa aacaacagga attcttcgtt
    11821 tcaacagcag agtagttgtt cagggctgcg gaccaatcgg actgatctgc attgcagtac
    11881 tccgtactat gggggttgaa catatctgcg cagtagacgg aaatgagaaa cgtcttgaat
    11941 ttgccaagag aatgggtgca gacacaagcg ttaacttcat gaactttaag ggaatcgaag
    12001 cactgacaga agctgtaaaa gaagctcagg gcggacatct tgcagatttc gcattccagt
    12061 gcacaggaaa cccgaaagct catgcaaaca tttataaatt tatccgcaat ggtggtggtc
    12121 tttgtgaact tggcttcttc atcaatggtg gagatgctac aattaatccg cactttgacc
    12181 tctgctccaa agagatcaac ctggttggtt cctgggtata tactctgaga gattatgtaa
    12241 caacctttga tttccttaag agagcaaaag caattggtct tccgatgtct gaactgatca
    12301 cagataagtt cccgttagag cagattaatg aagctcttca gacaaacctg gcaatgacag
    12361 gacttaagat cgcagttgta aacaaatagt tactgttcgc cggtaatatc ccgcaaagag
    12421 tattgctgtg aacagagtga acagtagcaa caaataataa gcctggcaat agaggagaaa
    12481 agaaatggca gaagctgtag gaattttaga ggtattcggg ctggcgacag cctttgtagc
    12541 aggcgatgcc ggatgtaagg cagcaaatgt ccgcctggag gtttttgata aaaacaaacc
    12601 agccaatgct gacagcctgc cggtaccgct ccttgtctgc attaaattca gaggaagtgt
    12661 aactgatgtt acagcggctg tggaagcagg catggaagtt gcaaacagaa tgactggtgt
    12721 ggtacagcat tatgtgatcc cgaacccgga agagggaacg gaaaaaatgc tgaagatcag
    12781 cgccctggat aaggattagc agttgcatat ccattgggca tcagttaaaa tataatcaga
    12841 tatttatttg tagattcagg aggaagcaga aatggcacag gaagcattag gaatggtaga
    12901 aaccagagga cttacagcag caattgaagc agctgatgca atgacaaaag cagctgaagt
    12961 agcattagta ggaacagaga agatcggatc cggacttgta acagttatgg tacgcggaga
    13021 cgtaggagct gttaaggcag cagtagaaag cggaagcgca gcagcatcca gacttggcga
    13081 attagttgct actcatgtaa ttccgagacc tcatacagac gtagagaaaa tccttccaag
    13141 catctgacca gcagattgag aagtgtaaaa aaggagttcg ctcatgagta aatcatatgg
    13201 atttatagaa atcactggtg tcgttgcagc aatcgatgca ctggacatca tgtgcaaaac
    13261 tgcagacgtt gagctggcgt catgggaacg taagctgggc ggacgactgg ttactattat
    13321 agttgaaggc gatgtatctg ccgttacaga agcagtaaat gcagcagcga caggtgcgat
    13381 caagaaaccg gtaagttatg cagtaattgc acgtccccac gaagaaatcg tcagaatggt
    13441 ggaattaagt gcaagtcgct ggaagaacaa tcagggggat gaataatggc tgaagagaag
    13501 aaaccggaag cagataaaaa tgcccctaaa aaggcagccg ctccaagaag aacgaaagca
    13561 aaaacttctt caaaaccgga agtaaaagct cagacggcag atacggcggc agaaacagca
    13621 aataaaacag aatcccagaa agaacagata aaggaaacag tatctcataa ggaggaaaaa
    13681 gttatgacac aggaagcatt aggaatggta gaaaccagag gacttacagc agcaatcgaa
    13741 gcagcagacc agatgtgcaa ggctgctaac gtagcattag taggaacaga gaagatcgga
    13801 tccggacttg taacagttat ggtacgtgga gatgtaggag ctgttaaatc agcagtagaa
    13861 agcggaagcg cagcagcatc cagacttggt gaattagttg ctacacacgt aatcccaaga
    13921 ccacatacag atgtagagaa aatcctgcct gtattaaaat agtaatccat cgtaactgtc
    13981 cggtatctgc acagcagact gccggatggt tataatccgt catatttgac agaaagcagg
    14041 tgtattcttg gaatctaata atattgaact gattaccaga atggtcattc aggcaatcaa
    14101 tcagaatgaa aaaaaaggcg atggattcat ggttcccatc ggggtttccg caagacacat
    14161 tcacctgaca caggaacatg tagaagcatt gttcggaccc ggatatcagc ttacgaagaa
    14221 gaaagagctg atgggaggtc agtttgcttc taatgagaca gttaccattg tgggactgaa
    14281 acttcgtgcc attgagaatg taagaatcct tggaccggtg cgtaaagctt cacaggttga
    14341 ggtatctgcg acagatgcca ttaagcttgg aatgaatgtt ccggttcgcg aatccggaga
    14401 cgttgcagga agtgcaccaa tcgcaatcgt aggtccaaaa ggagccgttt atctgaaaga
    14461 gggatgtatc gtggcaatgc gccatataca tatgtctccg aaagatgcac aggctgcagg
    14521 tgtgaaggac ggcgatatcg tatcagtaaa ggcagataat gagagaggaa ccatcttcaa
    14581 tcaggtcaag atccgtgtag acgacagctt tacactggaa atgcatattg atacagatga
    14641 agcaaatgca gcaaagattg ctacaggcac taccgtaaca ataattaaat aatatcgggg
    14701 gccaaaggtc aaaaagccgt tcgtgcctgc acgataaggt ttttgaacag aaacccttaa
    14761 gcgttaattg ggggcagaag tatttgcccc caatattatt atcagaaaca atttggaggc
    14821 tcatatgatc gtaggcaaag ttgtaggaag tgtggtatcc acacgaaaga gtgagaagct
    14881 gattggaagt aaatttatga ttatcgagcc tgtgcatcat atgaaaggcg acctgagcca
    14941 gctggttgcg atcgatatga tcggagccgg agttggtgaa tatgtattgg tggcacaggg
    15001 aagcgcagca agaataggct gcggcgtaga aacagcaccg gtagatgccg caattgtcgg
    15061 tattattgat gacggtgcag gattggagta acgccatgga aatcaaagaa ttacaggata
    15121 ttatacagca gaatggtgtg gtaggtgccg gcggagccgg attccctact tatatgaagc
    15181 ttacagacaa ggctaatacc attcttatga actgtgcaga gtgtgaacca ttactgaaat
    15241 tacacagaca gttattggaa aaacacgcat atgaaattat gaaaacattc catatgatcc
    15301 aggagacggt tggtgcttct gaagcaatta ttggaattaa gaagtcttat gtacagacaa
    15361 ttcatgcatt aaatcagcat attgaagaat ttcctggcat gaggctgcat cttctggacg
    15421 aagtttatcc gatgggagat gaggttgtac ttatttatga ggcaaccgga agagtagtac
    15481 ggccgggagg actgccgatc gagcagggag tagccgtatt taacgttgaa actgtataca
    15541 atgtatatcg tgctgtggaa gagaagcagc cggttacaga caaatatgta tctgttgttg
    15601 cagaagtaag tgatcctgtt acagtgagag ttcccctggg atgtactctg gaggaagtgg
    15661 tagcacaggc aggcagcaca acagtgaagg atcctgtcta tttcgtaggc ggcccgatga
    15721 tggggcgtat cggaaatggt tcagatccgg tgacaaagac aacaaatgcg attttggtcc
    15781 ttccaaaaga ccatcttatt gtagcgaaga agcagcggac ttcttccata gatttaaaac
    15841 gtgcagcatc tatctgctgc cagtgcaata cctgtacaga tttatgtccg agacataatc
    15901 tgggacatcc gatcgatccg gcgaaattta tgagagctgc atcaaataat gatttcagag
    15961 acctgaatcc atatatagat gcttccttct gcagttcctg cggtgtatgt gagatgtact
    16021 catgtccgca gagtcttgca ccgagaagtc ttctcgcaga tatgaagggc ggtctgagaa
    16081 aagcaggtat ccgtcctccg cagggtgtac agccgaaacc ggtacaggaa tccagagaat
    16141 accgtaaggt tccggaagaa cgtctgatgg cgcgacttgg tcttacgaga tatgacaagg
    16201 atgctcctct gaaagaagaa cttgtacagg ttaagaaagt aagaatatta ttgagccagc
    16261 acatcggagc acctgcacag gcagtggtca aagccggtga tgaggtaaca agagggcaga
    16321 tgatcgcaca gccggcacag ggcttaagtg ttggtattca tgcttctgtc agcggtaaag
    16381 taacagaagt aacagaccgt tacattatta ttgcagtaaa gtagaaagga cgtgcacaaa
    16441 atgagtaaag caatcggaat gattgaattt aaaaccacat ctacaggcgt tactgcagca
    16501 gatgctatgg taaaaacatc tgaggtagag atcgtcgagg cacagaccgt atgtcctggt
    16561 aaatatattg caattattac cggtgactta agtgcggtaa aggccgccgt tgatacggca
    16621 gtaactacat atgaggataa atgcattgac agctttgtgc tgggcaatcc gcatgaatcc
    16681 attttcccgg caatttacgg aactactcag gtagaagata tcagtgcgct gggaattctt
    16741 gaaacttatg atgcagcttc cattatcgaa gcagcagacc aggcagctaa gactgcgatc
    16801 gtagatttga tagaacttcg tattgccaaa ggtatgtgcg gaaaatcata tatgatgatc
    16861 accggtgaag tttctgcggt agaggcttcc attgacaggg caaaagaact tgtagctgcc
    16921 aagggtatgt acctggattc ttccgttatc gcacatcctg acagaagaat gatcgacagt
    16981 attttataat atccggggta agaagtttct gaccctgaca ctcataaaaa atttctcaaa
    17041 aaaagggggc aaagatatgc ttgcactgga gagaagaaat ctgattctcg aaaaattaca
    17101 ggcagaaaag cgggtggtgg tcagcgagct gagccagctt tatgatgtct ctgaagagac
    17161 catacgccgt gatctggata aacttgaaaa ggaaggactt gcgataaaaa gttatggcgg
    17221 tgctgtgatc aatgaggatg taagcattga tttgcctttt aatgtacgta agaaccagaa
    17281 tgttacagga aagcagaaaa tggctgaact tgcagcttcc cttgtgaaag acggagatca
    17341 tattttcctg gatgcgagta ctacggcagt ttttgtggcg aaagcattaa aggaaaaaga
    17401 acgtcttact gtaattacca attccatgga aatacttctg gagttagctg atgtatccgg
    17461 gtggaacatt atctccaccg gaggcgtaat gaaagaagga tatctggctt ttcttggatc
    17521 aaagacagac gaatccatac gttcttatta tgtagataag gttatctttt cgtgtaaggc
    17581 actggatttg gaatggggga ttatggaatc tcaggaagct tttggatcta ccaagagagc
    17641 gatgattggt tctggacgaa agaaaattct ggttgttgac agttctaaat ttgatcagac
    17701 agcgttttcc gtagctggaa gcatgaaaga agtagatatt atagtgacgg acaaagaacc
    17761 gacagaacgc tggaagaagc actttgagaa atttaatgta aaatgcctat atcctgtctg
    17821 acaaagaaaa taggagtatg atacaatgaa tacttttgag atgaaaaccg cgatccattt
    17881 tggggataac gcattagaca gattaaaaga gatcccgtat aaaagggttc tcattataac
    17941 agatccattt gtggtacaaa gtaaaatgat cgatctgatc actgctcctt taaacagtgc
    18001 aggtattgaa tacgatattt tccatgacgt tgtgccggat gcacctgtgg acaagattgc
    18061 agaaggggta aagaagttcc tggaatatca gccggaagca gttgttgcag tcggtggtgg
    18121 ttctgcgatt gattcttcca aggcaatcag agaatttgca ctgaagatca acaattacgg
    18181 aaaagtaggt ctgatcgcaa ttccgactac aagtggtacc ggatcagaag ttacttcttt
    18241 tgcagtagta aacgatactg cagcacatgt aaaatatccg ctgatctcag agagccttac
    18301 agcagatgaa gcaattctgg atgcagaact tgtaaggagt gttccgccgg ccatcacagc
    18361 ggatactggt atggacgtgt ttacacatgc gctggaatca tacgtaagta ctgcacataa
    18421 tgaattctct tctgcacttg cggagaaagc gattgaaatt tgcggggtat ttctgctgag
    18481 agcatatctg gacggcagtg atatgcatgc gcgtaagaaa atgcatgtag cttcctgtct
    18541 ggctggttta tcctttaata cagcaggtct tggaatcact cacagcatgg ctcatcagct
    18601 gggagcaatg ttccatattc cgcatggaag ggcaaatgct atgctgcttc cgcatatcgt
    18661 agaatttaat tctgatatca ataagcacag taagagccag aaagagtatc ttccggctgt
    18721 aaagagatac gccaatgttg cgcacattct cggactgagc aattataata aagtaatgac
    18781 ggtccgttct ctggtaaact ggattcagtt tatgcagaaa gagatgaata ttccgctgac
    18841 gattcaggaa ctgggaacaa ttgcaccgga agaatatttt gcagcaattg acaagatggc
    18901 agacgcagca cttgcagatg cctgcacagt gaataatccg agagttccga ctaaagaaga
    18961 tattataaag atttatacga aattatggtc attctgaaaa tgaagacaat aatttccggc
    19021 agatgctgac tgccgctgaa atcagataca ggagatggag aagagatgag tatttataca
    19081 aaaagaggag acagaggaat tacagatatg gctcatgccg gtaatatttc caagtctgat
    19141 gaccgtatcc gccttatggg tgaggctgat gaactgaata gtcatattga acttgtaaaa
    19201 agtatgctcc gtcagtcaga aatacttcag cttcttgaac gtattcaaaa gaatcttgat
    19261 ctgatcgcag cgggagtcag taacccatat gatcgtgact gtaaagtcag tgaaaaggaa
    19321 acagcagtat tggaggcgga aacagataaa ctggaagcac tgtgcgaaaa gcctgttccg
    19381 gagaagctta caggaaagag ccgactggct gcagagatag atattgcacg tactgttgcc
    19441 agaagaacag agcgctgcct tgcacaggtc agcgtgaagt ttggcgcaga tacagagagt
    19501 aagagatttc ttaaccgcct ttcggattat ctgtatattt tggcgagata tatagagtat
    19561 tactctgatc tttcagtgga actgtctgat gatcatgcgg gtgcattggc gaaaacgtct
    19621 gataataata cagatgcatt gccggaaccg tccgacagta atacagatgt attaaaaaag
    19681 acggcagata tcaatgaagc cgtcatccag gaggttctta aacgaatggg aattcagagc
    19741 aggataacat tggatacagc gaagaaactg atcgagagac tggagcagga agctgtgcgc
    19801 agagggcagc gtgcggtaat cgcggtctgc aatccggaag gaaatccggt tgcggtccat
    19861 gtgatggatg gagcattcct tgtaagcttc gatgtggcaa tgaagaaagc ttatactgca
    19921 gtggcagtga agatgtctac aatggaactt tcgaagatcg cacagcccgg aggaaccttt
    19981 tatggcgttg acaagctgga tggtggaaaa atcgttattt tcggcggcgg tattccgctg
    20041 aagtccggaa atacaattat cggtggactt ggaatcagcg gcggtacagg agaagaagac
    20101 catagtctgg cagagtatgg tcagtctgtg ttaaatgaaa tattgtaaga tggatgacaa
    20161 ctatttggca gtccgctgtt gaaggcacca gacagttgcg aaggagtatt aaaaagatca
    20221 gaacagcttt gaagagagct gttctggtct ttttgcgatg aactgattta tcttcgctta
    20281 tatttcccgg gagtcatgcc tttgtatttc ttaaaagtac gtataaaata actcagatca
    20341 ttaaatccgt tcctgtaagc aatttctgtg attgaatcat cagtagccgc cagttgtaaa
    20401 caggcttctt caattctctg tctgttcaga taatccacag gagtctgatg ggtcatttcc
    20461 gaaaagaacc tgcagaaata tttcggtgac atagagacag aagcagacag ttcttgaagt
    20521 gtgataggat tggcataatt tttttcaata aattccagaa cctgcttcaa ttgtaaaata
    20581 cgtttatagt ctctgcgcgt tctggtagga ttttcgataa agtaatgatt actgaaaacc
    20641 aaaccaaaaa agtggtaaaa ttgtccaaat acagtcagct catatccggt atctttctca
    20701 tacatggcat taaacagaac agaaatacag ttcagaatct gtggatgctc atctgaaaaa
    20761 tgtggaaaaa gcattgtttc ctgatgcagg attttctgga tatattctcc gcatacagga
    20821 ttgtttttca aaaaagtgtt catatcaaaa acaatgcact gatatacaca atcatgggga
    20881 attcctgaat gaaggattcc actgtgtaca aaaatgacat cattcttaac tgctgtaaaa
    20941 cttttttcgt ctaaagtgac ggtaagagaa ccttccagaa tacgaattat ttcatattcc
    21001 acatgccagt gataagacat gacatatctg ggatgtgtat gatcgatgtg atgaaactca
    21061 aatggaaact cataagtgcc tcttggacgg tcttcattat ggtctaaatc atgcaaaaga
    21121 actttcctcc ttacaaaatt tacagaaatt ttatgattaa aacagaaaaa gtgaatattg
    21181 tactgttttt tgctattata acacaagtaa ttttctgaat gcaattatat aatagatatc
    21241 agtaacaaag ttgagtggtc aggctgctgt gaacggagtg aacagtggtt atcgggctac
    21301 ttggcacaac aggtgtagag gttattattt ttgttatatt tgcagtcaga agatgctgcg
    21361 aaaagtgaaa atgtaatctt gggggttaga gcgtgtctga aaaatcattc ccgcaatctg
    21421 cacgccccac tttgcgggat atttcacccg aattcagttg ccgtagcccg ctacggcgcc
    21481 ctcatccggg caaaatatcc cacaaattgt gacgcacatc ttgcagaaag cctttttcag
    21541 acacgctcta g
//
