LOCUS       c00443_gnlPro..        15511 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BJLCDPEL_443.
ACCESSION   c00443_gnlPro..
VERSION     c00443_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:43:17
            Original ID  :: gnl|Prokka|BJLCDPEL_443
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2038
            Orig. end    :: 17549
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15511
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12038:14982]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12944
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..15511
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15511
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             1532..3271
                     /locus_tag="ctg443_4"
                     /transl_table=11
                     /translation="MFGILAKFFRFSGRENGNKFKLSMVIGLIEALASAMKIPAIMYIL
                     IGLLSGKPTGKYIGGSVAIMVFAIVVDVICKRYSTVLQTEGGYNASAFMRIKIAEHLRY
                     LPMGYFNSNSIGEISSITTNTMEILGDVAARVVMLTMQGILETSMIILMLFIFDWRIGL
                     IAAAGVLIFFGVNSVMQNAGKKDSEQKVVCDTELVNQIMEYLQGISEVKSYNLLGKQAK
                     RLNDANEACEKVNTKMEMLFVPYHFLQSVITKITGAVIVAGSAYFYINGTMSAVYAIGM
                     TISAFMLYSSLECAGNYSSLLHVVSVCVDKANTILELDTMDIDGKEIHPENYDIRLSNV
                     SFSYDKRKIIDDISLSVPQKTTTAIVGPSGGGKSTLCNLIARFWDVDSGEVTLGGVNVK
                     DYSMNSLMSNFSFVFQSVYLFADTIENNIKFGRQDASHEEVVEAAKKACCHDFISKLPD
                     GYDTVIGEGGATLSGGEKQRISIARAIMKDAPIVILDEATANVDPENEKELMDAVDALT
                     KEKTIIMIAHRLKTVRHADQIVVVDKGKIVQQGTHEQLMKQEGIYKRFVDARQQAVSWK
                     LVY"
     CDS             complement(3334..4773)
                     /locus_tag="ctg443_5"
                     /transl_table=11
                     /translation="MERFRQRYGIALTKKKLQEIILMLMAWEAVFAFSYLGYIELPAIS
                     TTTLHILVIVAAMMLGAQGSVPVVCVFVVTSMWIGTYSLSQLDRVFSPFASGMPLGSIM
                     LVFARVLFAAGAGWLFDLYFRKPRRYVYLGIAGIAAASTLLHGLCVFAALYCSFPMLRQ
                     MILENLFSYPIFRDWLSYVLAIIACCGIHWVLTRKSVKNRLSQLCDCPPAMQESGNRKQ
                     LIYSETVAVVVGILCILFLRKAIFKELYLQGIDVSENLHQNITAFLLQTLVALLALFSV
                     VSVLIQWIYEYYTAQRIRMNKKLMEQRMKSSVDVLTGVFSRLAYHECLEQYADSVPTDL
                     TVFLMDINGLKGVNDALGHEAGDELICGAAQCITQAVGDRGKIFRIGGDEFVVLGQMTQ
                     TQAQEILAALQRIAAAWSGTNVGTLSISSGCAFADDHPDFSVEQLTKAADLSMYAQKQE
                     YYRAKKLSSGTPVSSGNGVRP"
     CDS             5401..5865
                     /locus_tag="ctg443_6"
                     /transl_table=11
                     /translation="MDISLHYLTMANQMLIQKRLLERVKASGLTLGQPKVLDYLKNHDG
                     ASQKEIAAGCFIEAGSLTSILNRMEEKGLIERRMLNGNRRTFHIFMTESGKKSQKLVEE
                     AFVEIEEAAWKDISPEEAEAFMKIYHKIYSNLSETGCEETGKEGRNKLTN"
     CDS             5898..6470
                     /locus_tag="ctg443_7"
                     /transl_table=11
                     /translation="VNSLGVSLITKASLGTSPITSIPYVLSLSFPFTLGNFTIFFSVFL
                     ILLQLLILRKNFKLEHVLQIPISIIFGYFIDLTMLLFTWVNPQTYIMKIVYLLIGCLIL
                     GFGVYMEVLADVVMLPGESFVRAIVLTWRTNFGTTKICFDVSMAVIAAVLSFVFTGHLN
                     GVREGTIIAALLVGFVARVLGKKLASV"
     CDS             6599..6910
                     /locus_tag="ctg443_8"
                     /transl_table=11
                     /translation="MMMSYDSDPKEYARLAGFGYRMLAEAIKADLAYHISCPALLICGE
                     KDKAGSAQSYNKKWHQREGLPLKWIKNAGHNSNTDQPDEVNRLIEKFISEVDRRGVPR"
     CDS             7273..7479
                     /locus_tag="ctg443_9"
                     /transl_table=11
                     /translation="MGVSYNRLWKMLINKNMKRIEMQYLTGISGNILARMGKNQYVSME
                     TIEKICKKLDCTVDEMMEFTDDE"
     CDS             7806..8030
                     /locus_tag="ctg443_10"
                     /transl_table=11
                     /translation="MSEKTEITFMQTRLIRLASEEWHLPVEQIIHLFKEADVLGYIEKC
                     YGIFHCEGDEAVLEDITEFLEGKGIKISA"
     CDS             complement(8130..9545)
                     /locus_tag="ctg443_11"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTARLGLLQIRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNITEIPVAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGIFSNEAGLGSAPIAAAAAQTKEPVRQGLVSMTGTFIDTIVICTMTGLSIVL
                     TGAWQVEGLEGVQVTTYAFQHGLPIPGQISAFVLMICLVFFAFTTILGWDYYSERCLEY
                     LTNGHKKTILTYRWLYILAVFIGPYMTVSAVWTIADIFNGLMAIPNMIALFALSGVIVK
                     ETKAFFAAEKHKM"
     CDS             complement(10001..11680)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg443_12"
                     /sec_met_domain="HGD-D (E-value: 1.8e-17, bitscore: 54.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.4e-65, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPLELLESLGGECENFNHMPDGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKPHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGELLGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADA"
     CDS             complement(11673..12944)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg443_13"
                     /sec_met_domain="HGD-D (E-value: 3.4e-56, bitscore: 181.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWGAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLWPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             complement(13249..14868)
                     /locus_tag="ctg443_14"
                     /transl_table=11
                     /translation="MAKEIKFGAEARAALEAGVNKLADTVRVTLGPKGRNVVLDKPYGA
                     PLITNDGVTIAKEIELEDGFENMGAQLIKEVASKTNDVAGDGTTTATVLAQAMVHEGMR
                     NLAAGANPIILRKGMKKATDVAVEAIKNMSQTISGKKQIANVASISASDETVGQLVADA
                     MEKVSKDGVITVEESKTMHTELDLVEGMQFDRGYVSAYMSTDMEKMEANLEDPYILITD
                     KKISNIQEILPLLEQIVKVGAKLLIIAEDVEGEALTTLIVNKLRGTFQVVAVKAPGYGD
                     RRKEMLQDIAILTGGQVISEEVGLELKDATMEQLGRAKSVKVAKENTVIVDGMGDKDAI
                     ANRVAQIRGQIEETKSEFDKEKLQERLAKLAGGVAVIRVGASTETEMKEAKLRLEDALA
                     ATRAAVEEGIIAGGGSAYIHASKEVAKLAATLEGDEKTGANIILKALEAPLFRISANAG
                     LEGSVIINKVRESEPGIGFDALNERYVDMVSEGILDPAKVTRSALQNATSVASTLLTTE
                     SAVAIIKEDTPAPAANPGMGMM"
     CDS             complement(15000..15284)
                     /locus_tag="ctg443_15"
                     /transl_table=11
                     /translation="MTLVPLGDRVVLKQVEAEETTKSGIVLPGQAQEKPQQAEVVAVGP
                     GGVVDGKEVKMEVAVGDKVIYSKYSGTEVKMDGTEYIIVKQNDILAIVK"
ORIGIN
        1 gaactgcttc attcactttc gacagcattg tcacatagag caacgtttgc agtacttgca
       61 aatataagaa aagcctgctg tgacaagctg gcgcgggtac ctcttggtta tgtgaaagac
      121 acaccctccg gtacatttaa gaatatcatg gtggaaagaa tcgacagtat cgagacaaca
      181 ctggcacata ttgtccctga atttacctca aatttgctgg cacctgttat tatcctgatt
      241 tatttctttc tgacagactg gagactggca ctctggtcat tggtgccggt tatagtggga
      301 tttctttcct attttggaat gatgctggat tataaaccaa gcttcgagag aacggttcag
      361 acaacaaaag atctgaatga tgcggcagtg gaatatattg acggaatcga agtgatcaag
      421 gcatttggaa agacagaaag ttcttatgcc aaatttacaa aggcggctat ggcttatgca
      481 gattccttta tttcctggat gaaacggtgc tcgatctttc atggactgat gatggtggtc
      541 acaccttata cgcttcttac ggtattgccg tttggggcac attatgtagc caatggaaca
      601 cttgcgattt cagattttgt catctgcatt attttatcac ttggaatcgt tggaccgttg
      661 atcacagtgg gttcctatac agatgatctt ggcaagatcg gagtgattgt tggtgaagtg
      721 gcaggaattc tggaacagcc ggagcttgaa cgtccagaga aaagtaaaag tgttccaaaa
      781 gataactccg ttactcttga agatgtcaga tttggttatc acgacaaaga aatcctgcac
      841 ggagtaacta tggagctgaa agcaggaacg gtaaatgcaa tcgtaggacc ttccggaagc
      901 ggcaagtcga ccatcgcaaa gctgattgcg tctctgtggg atgtggattc cggaagcatc
      961 aaaatcggtg gagttgatgt caaagaactg gcatttgcag attttaaccg gaaaattgca
     1021 tatgttgcac aggacaatta tctgtttaat gaaacagtcc gtgaaaatat cagacaggga
     1081 aatccggatg ctacagatga acaaatcatc gaggtgacaa agaaaagtgg atgttatgaa
     1141 tttatcatgc agctggagaa tggatttgat acggttgtag gaggtgcagg agggcatttg
     1201 tcaggtggcg agagacagcg tatctcaatt gcaagagcga tgttaaagga tgctccgatt
     1261 gtgatccttg atgaggcaac tgcttacacg gatcctgaaa atgaggcgat tctgcagaat
     1321 tctatcgcaa agctggtagc agggaagacc ctgatcgtaa tagcacacag gctttctact
     1381 gttaaggaca gtgaccagat ctttattgta aatgatggaa atgtaacagc acatggcaca
     1441 catgaggaac ttctggtgtc atgcccgctt tataaggaaa tgtggaatgc ccatatttct
     1501 gtaaaagata ctgtgaagga gggagaatga tatgtttggg attctggcaa aattctttcg
     1561 tttttcaggc agggaaaatg gcaataaatt taaactgtcg atggtaatcg gactcataga
     1621 ggctcttgcc tcagcaatga agattccggc tattatgtac atattgattg gtctgctgag
     1681 tgggaaaccg acaggaaaat atattggagg ctccgttgcg attatggtct ttgcaattgt
     1741 agtcgacgta atctgtaaga gatactctac agtgcttcag acagagggag gatataatgc
     1801 aagtgctttt atgagaatca agattgcaga acatctgcga tatctgccga tggggtattt
     1861 caattccaat agtatcgggg aaatttcttc cattacaacc aatacaatgg aaatacttgg
     1921 cgatgtggct gcgagagtgg ttatgctgac aatgcaggga attctggaaa catcaatgat
     1981 cattcttatg ctgtttattt ttgactggag aatcggactg atagctgcag caggagtact
     2041 tattttcttt ggggtcaatt ctgtgatgca gaatgcaggg aaaaaagatt cagagcaaaa
     2101 agtggtatgt gatacagagc ttgtaaacca gatcatggag tatctgcagg gaatatcaga
     2161 agttaaatca tataacttgc ttgggaaaca ggcaaaaaga ttaaacgatg caaatgaagc
     2221 atgcgaaaag gtcaatacaa agatggagat gttgtttgtt ccctatcatt ttctgcaaag
     2281 cgtgataaca aaaatcacag gtgctgtgat cgtagcaggc agcgcatatt tttatatcaa
     2341 tggaaccatg agtgcggtct atgcgattgg tatgacaatc tcagcattta tgctttattc
     2401 cagtctggaa tgcgcaggaa attattcatc cctcttacat gtggtaagtg tatgtgtaga
     2461 taaagcaaat acaatactgg agctggacac catggatatc gacggcaaag agatccatcc
     2521 ggaaaattac gatatcagac tttctaacgt ttcattttcc tatgacaaac ggaagatcat
     2581 tgacgatata tcgctctctg tcccacagaa aacgacgaca gcaattgttg gaccgtctgg
     2641 tggaggaaaa tcaacacttt gcaatctgat tgccaggttc tgggatgtgg attccgggga
     2701 agtgacgctt ggaggcgtga atgtaaaaga ctacagcatg aacagtctga tgagtaattt
     2761 ctcatttgta tttcagtcag tgtatttgtt tgcagatacc attgagaata atattaaatt
     2821 cggacgtcag gatgctagtc atgaggaagt ggtggaagcg gcaaagaaag cgtgctgtca
     2881 cgatttcatc agcaaacttc cggatggata tgacacagta atcggagaag gcggcgccac
     2941 actttccggt ggtgagaaac agcgtatttc catagccagg gcaattatga aggatgcacc
     3001 aatcgttata ttagatgaag caacggccaa tgttgatccg gagaatgaaa aggagctgat
     3061 ggatgcagta gatgcactta caaaggaaaa aacgattatt atgattgccc acagattaaa
     3121 aacagtcaga catgcagatc agattgtggt tgttgacaaa ggaaaaattg tgcagcaggg
     3181 aacacatgag cagctaatga agcaggaagg tatctataag agatttgtgg atgcaaggca
     3241 gcaggcggtg agctggaaac tggtgtactg agaaatatat ataggtggct aaggaaaaaa
     3301 tgaaaaggga aaggaagagg tatatatttc tttttatgga cgcaccccgt tcccactaga
     3361 gacgggtgtg ccagaggaca gtttctttgc ccggtaatat tcctgtttct gggcatacat
     3421 ggacaaatct gctgccttgg taagctgctc tacggaaaaa tccggatggt cgtcggcaaa
     3481 ggcgcacccg gaggaaatac tcagcgtccc cacattcgtc ccggaccagg ccgccgcaat
     3541 ccgttgcagc gccgccagaa tttcctgcgc ctgggtttgg gtcatttgac ccagcaccac
     3601 gaactcatcc ccaccgatgc ggaagatttt cccccgatcc cccaccgcct gggtgataca
     3661 ttgggcagcg ccgcatatca gctcgtcccc cgcctcatgc cccagggcat cgttgacccc
     3721 ctttaagccg ttgatatcca tgagaaagac ggtcagatct gtcggaacgg aatccgcgta
     3781 ctgctccaga cactcatgat acgccagccg actgaatacg ccggtcagaa catctacgga
     3841 gcttttcata cgctgctcca tcagcttttt gttcatccga atccgctgcg ccgtataata
     3901 ctcgtaaatc cattggatca gaacgctgac aacactaaag agcgccaaca gagccaccag
     3961 cgtttgcagc aaaaaggcgg tgatattttg gtgtaggttt tcgctgacat ctatgccttg
     4021 caggtacagc tccttgaaga tggcctttcg cagaaacagg atgcacagaa tgcccaccac
     4081 taccgcaacg gtttccgaat agatcagctg cttccggttt ccggactctt gcattgccgg
     4141 aggacagtcg catagctgcg acaatctgtt tttcaccgac ttccgagtca gaacccaatg
     4201 gatgccgcag caggcgatga tcgccaggac ataggacagc cagtcccgga atatgggata
     4261 ggaaaacaga ttttctaaaa tcatttgccg cagcataggg aaactgcaat ataacgcggc
     4321 aaaaacgcac agcccatgaa gaagggtgct ggcagccgca atccccgcaa tgcccagata
     4381 gacatacctg cgaggcttcc gaaaataaag gtcaaagagc caaccggctc ccgccgcaaa
     4441 cagcacgcgg gcaaatacca gcattatgga tccaaggggc attccgctgg caaagggaga
     4501 aaatacccgg tcgagctggg acaggctgta ggtgccaatc cacatggacg tgaccacaaa
     4561 aacgcatacc accggcacac tcccctgtgc ccccagcatc atagccgcca caatcacaag
     4621 aatgtgcaac gtggtggtgg aaatggccgg aagctcaatg tatcccagat aagaaaaggc
     4681 aaacaccgct tcccaggcca tcagcatcag gatgatctcc tgcaatttct ttttcgtcag
     4741 agcaatccca tatcgctgtc gaaaacgctc catactcctt actcctccac atccttttct
     4801 tcatgtatta tacttatatt atacttattc ctgtgtgaaa agcaatacga ttcataaatc
     4861 tttgcaaaca tcaacctgga cgagcttcat gcaaagcatt ccaaatatta gcgtgaagaa
     4921 gcataccgcc tgttagatgc actcctgaaa cagtacaaca cataagaaaa cgattgctac
     4981 acattttaac gatttatgac aaaagcggct tcccgggacg gagagccgct gattttcttt
     5041 aaggaagttc tcaatgaagc tttccgtgca agggatgtcg gagccgacaa tggttaaagt
     5101 atttcgattt taacgcttct tgcaccaaca gcgtaaaaaa atatctttag aggcctttga
     5161 ttctcttttt tactcatttt ccaatgcatt ttccctcgat aagactttga aaggttatga
     5221 tccaattgct gttgatggct cgtatattta tgttgatgaa atgtatggac aatatgtgaa
     5281 aggagctgcg gaagtaacaa aagcggggtt gacatctttt gtaaaatagt tataattcta
     5341 aatattagaa atataactat tttgtttgtg cttaacacaa aaagggaagg aacgtgaaac
     5401 atggacatat cattgcatta tctgacaatg gctaaccaga tgctgattca gaagaggctt
     5461 ctggagcggg tgaaggcttc ggggcttacg cttggacagc cgaaggttct ggattatctt
     5521 aaaaatcatg atggagccag tcagaaggaa atcgcagcgg gttgttttat tgaggcaggg
     5581 tctctgactt caattttgaa ccgcatggaa gagaaaggtt tgatcgagcg gcgtatgctc
     5641 aatggaaaca gaaggacttt tcatattttc atgacagaat ccgggaaaaa aagccagaag
     5701 cttgtggaag aagcttttgt ggagattgag gaggctgcat ggaaagatat ttctccagaa
     5761 gaagcagagg cttttatgaa gatttatcat aaaatttaca gtaatctgtc tgagacaggc
     5821 tgcgaagaaa cagggaaaga aggaaggaac aaattaacaa attaaaaaga tacgtaatct
     5881 ttctgatcgg cctgttcgtg aactcacttg gtgttagttt gatcaccaag gcaagtctcg
     5941 gaacctcacc aatcacatcg attccgtatg tattaagctt aagttttccg tttacgttgg
     6001 gaaactttac gatttttttc agcgtatttt tgatcttact gcagttgctg atcctgcgta
     6061 aaaattttaa actggaacat gttttgcaga taccgatatc cattatcttt ggatatttca
     6121 tcgatctgac catgcttctg tttacatggg taaatccaca gacatacatt atgaaaatcg
     6181 tatatcttct gattgggtgt ctgatccttg gatttggtgt gtacatggaa gtgctggcag
     6241 acgttgtaat gttgccggga gaatcttttg tccgagcaat cgttctgaca tggagaacca
     6301 actttggtac gacaaaaatc tgctttgacg tttccatggc agtgatcgca gcagtcctgt
     6361 cttttgtatt taccggacat ctcaatggtg tgcgtgaggg tacgatcatt gcggcacttc
     6421 tggttggatt tgttgccaga gttcttggta agaaacttgc atctgtctga aaaagatgca
     6481 acacataaga ttcagaaaaa agacaaacag cgtgcggata actaccatta ttacatagga
     6541 cgcatctgag gagcatcagc aaactttgat ctgatattct gattcttcat ttacagtaat
     6601 gatgatgtcc tatgattcag atcctaaaga atatgcaagg cttgctggtt ttggttacag
     6661 aatgcttgct gaggcaatca aagcagattt ggcatatcat atcagttgtc cggcacttct
     6721 tatctgtggc gaaaaagata aagcgggctc agcccaaagc tacaataaaa aatggcatca
     6781 gagagaaggt ttaccgctta aatggataaa gaatgctggt cataattcca atacggacca
     6841 gccggatgaa gtaaacagac tgatagaaaa atttatcagc gaggtagata ggagaggagt
     6901 gccccgatga aattaaatat acagtggaaa aagtattatg tgggattgca ttgatatggt
     6961 cagtgacctg ctgatgcagg cagaggcagt ctgagacgac tgcagatgac agggaaacgc
     7021 acgctagacc gccggacgaa tgaaactgat aacaatgttt acagggcgaa atgcctggaa
     7081 aggatggatt catggaagca ccagatggtg agatttcatt tgattaattc agagtaaatg
     7141 gttggagagg ctgccctttg ccgtggcatc cttttttcca ttttacagaa gatatcaaaa
     7201 atcacaggta ttcaacctaa cgaaatcgtg atataatcaa aatatgttta tacgaaaaga
     7261 tggaggtagc ttatgggcgt aagttataac aggttatgga aaatgctcat aaataaaaat
     7321 atgaagcgga tagagatgca gtacctcacc gggatcagtg gaaacattct tgccaggatg
     7381 ggaaaaaacc agtatgtatc aatggagacg attgagaaga tttgcaagaa actggactgc
     7441 accgttgatg agatgatgga atttacagat gatgagtaac aggagcagac atgtcaaatc
     7501 attaaacctg gcagaatgct tcagaagtca aaaagaattt gaaaaaagat aacacgtcgg
     7561 atacggcata aatctcttag taacgctaag agcgcacttc gatacagaca atttcatctg
     7621 cctgtatcgt gcaacctgcg gtgctgctcc cggttttgag aaatctcaat ccgggaaata
     7681 cagcgaaatc aaagatttcg tacaagggga gtttcccctt gcggcacagg tgcctatccc
     7741 aataaagttt atgactgaat atttcagata cagacatata aagttataaa tttggaggat
     7801 tcattatgag tgagaaaaca gagattactt tcatgcaaac aagactaatc cggcttgctt
     7861 cagaagagtg gcatttacct gttgaacaga ttatccactt gtttaaagaa gctgatgttc
     7921 ttggatatat agaaaaatgc tatgggattt ttcattgtga aggtgatgaa gctgtgcttg
     7981 aagacattac agaatttctg gaaggaaagg ggataaagat tagtgcttga gttaaaaaat
     8041 ataagcaaaa aaatcctctg atcaggattg ctataaattc cataatcaga ggatttactg
     8101 ttttctgtta ttttattact tttgatttct tacattttat gcttttctgc tgcaaaaaat
     8161 gcttttgttt cttttacgat cactccgctt aatgcgaata atgcgatcat attcggaatc
     8221 gccatcagtc cgttgaagat atctgcgatc gtccatacag cacttactgt catgtacggt
     8281 ccgataaaca ctgccagaat gtaaagccaa cggtatgtaa ggattgtttt cttatgtccg
     8341 tttgtcagat attccagaca tctttcactg taataatccc atcccagaat tgtagtaaat
     8401 gcaaagaata ccagacagat cattaataca aatgctgaaa tctgtccagg gatcggaagt
     8461 ccgtgctgga atgcataggt agttacctga acaccttcca gaccttctac ctgccatgca
     8521 cctgtcaata cgatggaaag acctgtcatt gtacagatca cgatcgtatc aataaatgta
     8581 ccagtcatac ttacaaggcc ctgacgtaca ggttcttttg tctgagctgc tgctgctgcg
     8641 ataggtgcgc taccaagtcc tgcttcattt gagaagatac cacgagccac acctttctgc
     8701 atggatacga tcattgttcc taccacaccg cctgtcactg ctgacggatt aaaagctccc
     8761 ttcacaactg taacgatagc taccggaatc tctgtaatgt ttaaaagaat cagcgcaaca
     8821 ctgaagatca gatagattac tgccataaag ggcacgataa tctggctgac tgttgcaatt
     8881 cgtttcagac ctccgatgag gattgctgca acacatgctg caaggattaa ggaagaaatt
     8941 acaactgccc aggaatactc tccaaggaac ggaatattta cgcagtttga tttgtttgga
     9001 tcaaagaagt tctgaactgc actggaaata ccatttacct ggctgaatgt accgattccg
     9061 aaaagaccta cacatacacc aaagaatgca aagatctttg caagccattt ccattttgtt
     9121 cccatacctt tctcaatata atagaaagga ccgccaaggc tgtgaccgtc ttctgctacc
     9181 acacggtatt tcactgcaag aagaccttcg gaaaattttg ttgccattcc gaagaatgct
     9241 gcaagaatca tccagaataa agctccggga cctccggcac agacagcagt tgcaacaccg
     9301 acgatattac cggttccgat tgtggcactc agtgctgtac ataaagctgc aaagctggaa
     9361 atctcaccgt cgccttcttc ttcgttctta aacatccatt tcaatgcaag ggggagtctt
     9421 cgtatctgaa gaagtccaag tctggcagtt aacaggatac cacctgccat gatcaggacc
     9481 ataaggggca cgccccagac cagattgtct actgttgtca aaaaagaatt gatcgcttcc
     9541 cacataataa taaatctcct ttttctttta aaaagtgtaa tatattgtac agctgggaaa
     9601 caaagtaata acagaccgtt tcaaaaatca gaagttcaga aaatactgtt catatagttc
     9661 atatgaatca gcggggatga taaagcatcc tctgtccttt tgcctgagag attcaagaca
     9721 cgggtcagat aaccaattgt gggaagttat cagcattccg tgttatttgc accttcggcc
     9781 cccgatctaa cgggtgtctc cagagaaacg atccatttgc agttcttccc tgcatccagg
     9841 gaacctgaga gttttactcc ttcggcgggt atagcctttt atggcttcct ctttcctgca
     9901 aacttcacct cgttaatttg ctgttactgt ggtatactat agctcttaaa tttgaactcg
     9961 tcaatagaaa attaaacttt tataaaaaaa gtataaaaat ttacgcatca gccatatcag
    10021 ccgcaaacag tgctgcgcca agtgcaccgc aaagctgagc cttgtcactg atcaccagct
    10081 ttgttcctag cttctcttcc agtgtcttta ccaggccctt attcttagaa acaccaccgg
    10141 tcatcatata tttctcctca ccgcccacac gtctggtaag agctgcggtt tttacggcaa
    10201 ccgccttatt cagaccatga acaatatcat ctgttgcctt attctgggcg atcagggata
    10261 caacttctga ttctgcaaat actgtacaca tactggaaat tgtaatatct tctttgaatt
    10321 ccagcccaca ttcgctcatc tgatccagat tcatttccat ggtacgtgcc atcatttcca
    10381 gaaatcgtcc ggttcctgcc gcacatttgt cattcataac aaagtttgca actgcaccgt
    10441 tctcatccag tcggatcacc ttgctgtcct gtccgccaat atcaataaca gtacggactt
    10501 ccggattcag gaaatgcgca ccccttgcat gacaggtgat ctctgtgata ctcttatcac
    10561 catttttaat agctgtacgt ccgtatccgg tagtaaccag cgcatcaata tcttctctct
    10621 gcaatccggc ctccttcaat gcttctgcaa gggcacgatc tgctccgata gcagctcctg
    10681 ctcctgtagg caggataata ctggtcacaa tctcatgatc tttatttaaa atcaccacat
    10741 ctgtactggt ggaaccactg tcaatccctg cgaaataacc ttttcccatt tttctctctc
    10801 cttttgtgtc tccatctatg gtctgctcca gtgtttcagg ctgaatgctc tctgcaaaag
    10861 cttccagtct ggtaagaagc tgaccgctgc tctgaatagt ataatctgat tcaattttta
    10921 aaagaggtac atctgtatgg ttcttgatct cagcatattc gaagctgtaa aaatcacaaa
    10981 acttcactgt atgataaata attcctgcaa cagacggatc attataaagc ttcttacggc
    11041 ctgtcggatc catcatccgc atacatggaa tctgccccag aagctctcct gcataccagt
    11101 ccatcagttc atcaaaagaa gcaccctccg gtggaagtat atttcccaca gaacggttat
    11161 gcacacaggt atcattctct acaggaaggg gcatagcctt gctggtcatt tcaaataatt
    11221 cctgccccat tctggcacca agcactgcaa tatgaggctt tgtgattttc tcctgtgcat
    11281 ggaaagcagc ccggaatttt ccggcatcaa actctgtgcc tttgtactgt gcataagcct
    11341 tggccagccc ttttaactgt acagccatac gttctctgct acaggcactg tcacaatgaa
    11401 gcacatccaa aatataaagg aaatccagct taccgctttc cagcaaaatg tcatacacac
    11461 ttcggatggt atcacagcag ctcaccagaa caagttcctt gattttcccc tccatgactc
    11521 cttccagaag tgtttttcca aaaccacaga tattgggatg ggaaacctga tctgcaaggt
    11581 caaagccatc cggcatatgg ttaaagttct cacattcccc gccaagagat tccagaagct
    11641 caaggggggt atatttacag acataataag ttttattcat tctcagcacc tcccagcatt
    11701 tccagaaaag ctcccagcct ggtggaagtc tgtccttctc ctccatggct tcgatcacac
    11761 ccgtcaccgt ccaggatcaa aaggggcaga ccggcttcct cgaacttctt ctttgcaagc
    11821 tgtgccgcac caagcgtatg tttacatccc caatgtccaa accacacagc accgtctgct
    11881 cctgcctgtt tcgcatggcg gataccggct tcaatccttc taagggcact tccattcagt
    11941 gaatgataga ccattctttc tgccattgct tcaaaggggt tctcaggatc aaaatccggc
    12001 tcacaggttt ctgcaagttc acatcctacg atctgggctt tctcactgaa gcaaagctcc
    12061 tggcgcactg catccgacca gaatggaatg gtatgcatcc agtaaatgtg cttccctttc
    12121 gctgccggtg ctttcttaat atcttcaaga agcatctgtg tatacttctc ttcttctgct
    12181 gttcccagaa ggatattgtt tgtcattcct gcatacaagg gtgtgaccag atcagagggc
    12241 acatatctgt ctgcacgcat ctgctgatat tttttgtaat tctccagagt ccgcttactg
    12301 caggcaagac gttcctttaa tctgtcctca gagattgttt ttcctgtatt tttttccaga
    12361 aatattttta aatcctttaa ctgatctgcc acatactgta cattctctgt ggtctgattc
    12421 catggtacat caatggcaaa tacaggtacc tggtaaaaat ctgccagggt acggaaggtg
    12481 agcaggttag catcgcaggt caggttggta taaacaatac atttaggctt tggcagaagt
    12541 cctttctgcg ctgcaccaag aaatgtcttg tgataactgc acagtgtctc tgcaattccc
    12601 tgattctctg cctgctgcaa aaatgccctc tctgctttgc ttgcagaaag atagcaggaa
    12661 aatccttcta cattataggg atgtaatccc acctcctgca tcatttcgca gggtgtaaaa
    12721 atacttacaa taacagaatc ttccggtttc tgaaggggcc acagcatggt atccatcatc
    12781 aggtttgcaa gatgcctgtc tgcaggcatc agtctcttgt cctgcatgta acggaacttc
    12841 agattctgcg ccccccaacc ggtttttaac agccggcggg ctgactgagg ctttttatcc
    12901 gtcagatttt ccacataatg accaaatgtc tcaataatct ccatagtctg tctcttcctc
    12961 attatggtaa taataattta tcaattgtca gtgcacaaat agtgccacgg aatattttaa
    13021 taatatcttt ttgggaagtc aagttgaatt ttcgttactg ttcacacacc actgttccgc
    13081 gaggtgtttt ggcatgaata tgccaaaatc ccgagacata caagccaaaa ttccattgcc
    13141 gcaggcaatc tggaatgaat tttggctatg ttactgtgaa cggagtgaac agtaacatac
    13201 tatttttatc tgagcatact gcggtataat tttatcgttt attaaaaatt acatcattcc
    13261 cattccagga ttagcagccg gtgcaggtgt gtcttctttg ataattgcaa cagcagattc
    13321 tgttgtaagt aatgtagatg caacacttgt agcattctga agagcacttc ttgtaacctt
    13381 tgcagggtca aggatacctt cgcttaccat atctacatat ctttcattca gagcatcgaa
    13441 accgattccc ggttcagatt ctcttacttt gttgatgatt acagaacctt caagtcctgc
    13501 atttgcagaa atacggaaca gaggagcttc cagagctttc aggatgatgt ttgcacctgt
    13561 cttctcgtca ccttccagag ttgctgcaag ttttgcaact tctttggatg cgtggatgta
    13621 agcagagccg ccacctgcga tgataccttc ttctactgct gctcttgtag ctgcaagagc
    13681 atcttccaga cgaagcttag cttctttcat ttctgtctca gtggaagcac caacacggat
    13741 aacagctacg ccgccagcca gttttgcaag tctttcctgt aatttttctt tatcaaattc
    13801 agattttgtt tcttcaatct gtccacgaat ctgagcaaca cggtttgcga ttgcatcttt
    13861 gtcacccata ccgtcaacga taactgtgtt ctcttttgca actttaacag attttgcacg
    13921 tcctaactgc tccatagttg catctttcag ttccagacca acttcttcgg agattacctg
    13981 gccgcctgta aggattgcga tatcctgaag catttctttt cttctgtcac catatcccgg
    14041 agctttgaca gctactacct ggaaggttcc tcttaatttg tttacgatca gagttgtaag
    14101 agcttcaccc tctacatctt cagcaatgat aagaagtttc gcaccaactt ttacgatctg
    14161 ctccagtaat ggaaggattt cctggatgtt gctgatcttc ttgtctgtga tcaggatata
    14221 tggatcttcc agatttgctt ccattttttc catatctgtt gacatatatg cggatacata
    14281 tccacgatcg aactgcatac cttctacaag gtcaagttct gtgtgcattg tcttggattc
    14341 ttctactgtg ataacgccgt ctttggaaac tttttccata gcatctgcta ctaactgtcc
    14401 aacagtctca tcgcttgcgg aaatagatgc aacgtttgcg atctgtttct tgccgctgat
    14461 tgtctggctc atgttcttga ttgcttctac agctacatct gtagctttct tcattccttt
    14521 tctgaggatg atcgggttag cgcctgctgc caggtttctc attccttcgt gaaccatagc
    14581 ctgtgcaaga acagtagctg ttgttgtacc atcacctgct acatcgtttg ttttggaagc
    14641 aacttctttg atcagctgtg cgcccatgtt ttcaaatccg tcttccagtt cgatttcttt
    14701 tgcgattgta acaccgtcgt ttgtgataag cggagcaccg tatggtttgt caagaactac
    14761 gtttcttcct ttcggtccta atgttactct tactgtatca gctaatttat ttacaccagc
    14821 ttcaagagct gctctggctt ctgcgccgaa tttaatttct tttgccatga taatatgacc
    14881 tcctgattca aattttgatc tctatgaatt ctttctgata cttagccggt atttcatgtt
    14941 acatcctgta aatattatct tataagtatc ttcatttatg ttttctattt tgatattgct
    15001 tatttaacaa ttgcaagaat atcattctgt tttacgataa tgtattctgt gccatccatc
    15061 tttacttctg ttcctgaata tttggagtag ataactttat cacctacagc tacttccatt
    15121 tttacttctt tgccgtcaac aactccgcca ggtcctacag ctacaacttc tgcctgctgt
    15181 ggtttctcct gtgcctgtcc cggaagaacg attccggatt ttgttgtttc ttctgcttca
    15241 acctgtttta atacaactct gtcacctaaa ggtactaatg tcatgatcta tatcctcctt
    15301 tattctccaa ctaaagcttt cctgttaccg tactctttcc gttatcgcaa aatatccggc
    15361 aactgtttcg gcactctgtc taattctgcc gatttttgct agcactcatt tacttcgagt
    15421 gctaatcact gtccttatat tattgaaaat gagtcgattt cgcaagtgct tttatcatta
    15481 taaaataatc tatattctct tttttactta t
//
