LOCUS       gnlProkkaFCOEGCIF_89   14305 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FCOEGCIF_89.
ACCESSION   gnlProkkaFCOEGCIF_89
VERSION     gnlProkkaFCOEGCIF_89
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:18:40
            Original ID  :: gnl|Prokka|FCOEGCIF_89
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14305
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14305
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2241:5352]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2242..5352
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..14305
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14305
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(292..621)
                     /locus_tag="ctg89_1"
                     /transl_table=11
                     /translation="MKLVGSRKLTWGICSIGVLLAIVSVFFLPQIIPVHFANGIADDFG
                     NKVEIFLFPILLIIITLLTGKENIKYFLTHSKTFLTDIQYNLMIDGVLGIVLIAEIYVI
                     YASFV"
     CDS             complement(803..1570)
                     /locus_tag="ctg89_2"
                     /transl_table=11
                     /translation="MERVLIISYIISMILTAGFIYCIYREKYWVFEFVNRIKKPIQQLV
                     YVFLMLLSSYAYICFSLLIKADFNAVICAVLLLLLIWAMDYLFSLCFKKNDLGISEKKR
                     YIFMAYVGACISGFIIASRDASKMALEIPNITISVLIGAYVPFTLLLEDGKKGKVELQS
                     MKEEWEEKYKKTFRERKVKDILSALLFAMVYGVLLVGALSPAQNIINDIASGIGMGMAT
                     VVVAFVGLVEVKNRLTKRRNKREDADQEKSDTE"
     CDS             complement(1719..2261)
                     /locus_tag="ctg89_3"
                     /transl_table=11
                     /translation="MIEMKFSKNDEEDGLFRISSRDIVGFYNCSSKQERKITDIIKCYG
                     TTKSIKEVELKNMKPEDNVTVSRYIERNVGSIINKDYVIEGFLGMGKLSDCKDEMVSRL
                     DISKRYCLEILVAFLQEADIIILHEMFENVWNHTIEEILVEFSLRGAVVVFSEHGEESL
                     MKLPMHSYDLSGRCVGW"
     CDS             complement(2242..5352)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     925.3; E-value: 7.5e-280)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_4"
                     /sec_met_domain="DUF4135 (E-value: 8.5e-104, bitscore:
                     337.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3e-68, bitscore:
                     219.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKSSYLSERVYDAIPSEINMESLEYWKKILKEEGLQYVKKNHLE
                     YFFGFINNCAFSSHEKSQPRNFVKLSLNKKAFRHEGEKMVFGAFYDPFVQEANRQLREI
                     VIQRRYINESILFDFQQFLFNSLNNLCIRTLIYEMHICGQEGVLRGNESEQYQYYIDHF
                     LKDKQYLNDLFSLYPVLERRINEIIQNAIDIYKEVIERIEKDADVLMKKFNITEKGFVV
                     NHLSTDFSDSHKKGRRVFCVEFVSGDKILYKPRSLQNEIKLQEITNYFYRICNLGSYEY
                     SILDKEMYGWCEIVIQRDCKSIEELSRYYQRIGIILFINYLLEGGDIHFENLIACNEYP
                     VIIDAETFIGNIEENNGKSAAEKVASLLRKSVLYSGILPFYSWNNAGDTGINMSAISGE
                     EGQKFPIKIPFIINPKSVNMRVVYDYPVSKGNHNLAMLKGRFIQPSEFADKIIQGFESA
                     YLGAMENTETLLRIIQQYGELEVRYLIRNTQQYAIVLSSSYHPELLVDGGARNLFFYSL
                     ANGNLQNQRSRSLIEYEIEDLLSGDIPYFYFRGSKKNIYTWDGREVKDFFSKPALQQIE
                     ENIQNLSYKNLEQQTQYIKITFNMENAGTRKIKNKRLKLDLYSNMAKTAEELAKELLDK
                     IGTNAIYSEDGADVNWIGVKLFGIKENQWMIQALPNTLYDGTVGINLVFHLYEWIYHDR
                     KYHKICEVLDNRLLRYIDTISEGEQNIEDFNTGIFSGEGSILYTLGILYEIYDDIKYKE
                     YFDKWLNCMETLILEDRLFDMISGNSGIVLVLINMYRKTKKPIYLQKAIQIAEQLIENM
                     ITENGKVGWKSEVVPEVLAGFAHGNSGFIELFSRLYEVYPQTKYLDILSSLVEYENSLY
                     SEKDNNWIDLRKFSEVDQHKSQPIAWCHGAAGILLSRLTLYNAIKNLGETALLQQAIKD
                     ISLAKNKLIEDGLHAGFCLCHGNMGNLLILKRYAEIFDDKQVRSICDSRFEQILEFLNE
                     ENILPTELYNPGFMTGLSGIAYALLKYKMPKLPLLIGVEGIYDRNEV"
     CDS             complement(5407..5580)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg89_5"
                     /transl_table=11
                     /translation="MRKFDRTNMKYNNPAGDLLTELEAADLTSNKVDSLASSGVVCTIS
                     VECGSIFTLACC"
     CDS_motif       complement(5506..5580)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MRKFDRTNMKYNNPAGDLLTELEAA"
                     /locus_tag="ctg89_5_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5407..5505)
                     /prepeptide="core"
                     /locus_tag="ctg89_5_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="3061.5"
                     /monoisotopic_mass="3059.5"
                     /core_sequence="DLTSNKVDSLASSGVVCTISVECGSIFTLACC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRKFDRTNMKYNNPAGDLLTELEAA"
                     /leader_location="[5505:5580](-)"
                     /alternative_weights="3079.5"
                     /alternative_weights="3097.5"
                     /alternative_weights="3115.6"
                     /alternative_weights="3133.6"
                     /alternative_weights="3151.6"
     CDS             5981..6511
                     /locus_tag="ctg89_6"
                     /transl_table=11
                     /translation="MKTRNEIYQGEGAQLLRFITTYHSLQYEQILRLFSKNRESIKSLI
                     TSLVKQKRIIYDKENGLLCDSQESANNPDYGMIASFWVLLDFKTAIMYHTDGEFPVKLN
                     FFSKDEWYEVLYVPQEQEYLINHVMESQTKSDAKRLVVLETEEQAAKIHITGVIAFCLV
                     DSSTGSVSYYAKK"
     CDS             6519..7184
                     /locus_tag="ctg89_7"
                     /transl_table=11
                     /translation="MNTKTVFDRLQSIDDEVQKLHNTIFALKTTDIQAYADKYEELSIS
                     AALRSERIACQLRNLVYTTTDTGKKDYLKQAAAVQGIKISFSNSVLSITMPGLLPKRKL
                     RTNTAFLHEPLNLALQTYVTEHSIPLYKRCVVCFSQIYDQSLSLQRIRDYDNLEFKQIL
                     DTIASYVLVDDTGLFCDSYHTTELGNYDHTVIFVMKPEIFPGWLKNRKSSIKTISEIS"
     CDS             7324..8430
                     /locus_tag="ctg89_8"
                     /transl_table=11
                     /translation="MIKTDSIKYQLLEMVGLCGEFPSGQLNRLIESDSYAEKVVTDLKQ
                     SKLIRTHYKDGLRGYRLTKRAKELLLSQNPCRFQNYLTGNAETNLIRSELPRRLRLHQK
                     AETYLTLSHAGIPFFPDEKPLLFSESGEAATFPVRSLPLFYSSREIKNLGAATTKIKNS
                     RCIGILMAPHCVYAVYNTGNTLLKWEYKTEVRLNAFLQHYLQGLPYHGPPTVYAIMTGS
                     DMDMAFRLLTSTGGYKKTLFMLDTAYEHFYFLPNNSYGEYLLRLLVQPQRMMQLNQLLL
                     SDCFPQREDLPIEHDGIDSQEKPILLAYDFDMQRINRFNTGLNIYGLSGNLICFDFQLP
                     CLKKYLTADIHFSSIDFQKFKRRFFNEP"
     CDS             8420..10426
                     /locus_tag="ctg89_9"
                     /transl_table=11
                     /translation="MNRKWWKFLFLLPISVCTLYAGGYAAQFIKNYQEWTSAGNFAGNG
                     TYPQAASLHPLVCFHTALIDFPYNLYGIFLCLVLLGLLTFLLMRMGYDRNGEISDHDRN
                     LNYSTKGTYGTSGFMTPDEMMKVLELTGDVKKNKGTILGKLNGKAVCLPYKTRMNKNIA
                     VYGASGSMKSRAFARNMIFQCVARGQEGNNASGESLIITDPKSELYESMSAYLENEGYV
                     VKAFNLVNPENSDSWNCLGEINGQETMAQVFADVIIQNTGSGKGDHFWDNAEMNLLKAL
                     VLYVDQGFPPEARNIGQVYKLLTMSSEKELNSLFDLLPVSHPAKVPYCIYKQASDTVRS
                     GVIIGLGARLQVFQNKLIRQITSYDEIDLTLPGKQKCAYFCITSDQDSTFDFLSSLFMT
                     FIFIKLVRYADKYGEEGKLPVAVHILADELANTGAILELNKKISVIRSRNLSISCIFQN
                     LPQMQNRYPYNQWQEIIGNCDTQLFLGCTDEVTATFISNRSGDVTVGVSSEAKQLNSWR
                     VSDYTPEYRQTKSIGKRKLLTPDEILRLPLDTALVILRGQKVLKVEKYDYTLHPDAQKL
                     TPRKASEHIPEWRKNGSSEETDYRPQSSSGSSKRKRRPSSASIAKQKPHFTSEPVYQEP
                     TPDDFMEDFLQENFIEDSPDSGMVPLDKDSIMS"
     CDS             10452..11381
                     /locus_tag="ctg89_10"
                     /transl_table=11
                     /translation="MANETMNLNTPILTLDSDTVLETAQSKADLIWHDIQNAYRTRKIL
                     TGILGGIEKTEAGSLIAIIYYKDYRAIIPISEMMINLIQDETHDYGDLSLRQNKVLNNM
                     LGCEIDFVIKGLDTKSRSIVASRKDAMLKKRQIFYFDQDSSGQTKIYEDRIVQARVIAV
                     AEKVVRAEIFGVETSILARDLSFDWLGDARERFQVGEHILVRILTIQGDSPETLSIHAD
                     VKSVEGNTSKENLKNCRVQGKYAGTVEDIHKGTVFVRLELGVNAIAHSCYDSRTVGKKD
                     KVSFVVTHIDEDRNVAVGIITRIIKQNI"
     CDS             complement(11480..13846)
                     /locus_tag="ctg89_11"
                     /transl_table=11
                     /translation="MNVKNKKIEKSMLRIIARKNTFDNKLTFGAIVLTIIIAISLITGL
                     FLIQIGNRTAEQKVLSQMQQVSIANLTTSKIEELQKNKLIEELVPYKSGFEILIDNKKI
                     QAVYMPNNTEVIHTYRILKGNAPIDKNEVVINENLLQLLNKEIGDELEVSNNDGIFEKF
                     IITGICENVSSTGSFFYVSQRYAEEGKLFTEIPYMALIRINNAEIMNIVEFENTIYDMA
                     DKYDIDRKEIYFNSKFLGSLGDESSFGMTFIYSFFIFGVSIIVIYSIFYLSVSNRVVQI
                     GNLRLIGMTKKQVKSLIRMEGDICSLLGISIGVVVGLCFAIFIEPNGVNIVNISIVCTI
                     IMIIGYLVVRISILTPSRIASSITPIENVKFLSFQDGKSFSSKSYSHLTAFTLAKKNIY
                     RERKKKFLILVSLVISGVLFVVGVTFLNSWSEEEFARQGNLEQGEFYIGINHNTLINGK
                     PYGISEYQIKTPFSDELIKNIADIPNVKNILIEKRTAGIIEYAGEDMEIPIIPITEENK
                     AEVLDSLDDQWTYEELVEKNGMIILGTDVQKDVYHNCPIKGENLTFRWFDGQEHSDNII
                     IAGTSEKSFNEGFYLTPETIKKFWGDMDITASIILSVSDYKMNGDAVTQKLEKILLNHP
                     DLVMQTLKETLKENADIIEKTRMQILGVSFFIIIFSWLNLICISMSSIATRRREFAMLE
                     AIGMTKKQLKKMIMYENILLIILSIAVTLILGNGLGYVLVEALSKNGLSYFVYQLPCPH
                     IIIYILLVLCVTICMVNAILKLQRKVSLVERIKID"
     CDS             complement(13970..14119)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg89_12"
                     /transl_table=11
                     /translation="MKKEIIEESKELPELTEEEVNIFCSCDTQLKIHCHHDCITQNAWI
                     SHDK"
     CDS_motif       complement(14045..14119)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKEIIEESKELPELTEEEVNIFCS"
                     /locus_tag="ctg89_12_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13970..14044)
                     /prepeptide="core"
                     /locus_tag="ctg89_12_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="2793.1"
                     /monoisotopic_mass="2791.3"
                     /core_sequence="CDTQLKIHCHHDCITQNAWISHDK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKEIIEESKELPELTEEEVNIFCS"
                     /leader_location="[14044:14119](-)"
ORIGIN
        1 ttttgataat catttacaga gttaaatatc gaaaacattt cattcagttc accatgtcgt
       61 tattgttata tgttatacta tgtacgaatt tttctttccc ttaatttttc ccatattaag
      121 gttcatgaaa accaatgaga gaatataata caagggaaag agtaagggaa agttcacttg
      181 ctacaaactt agtattttca agggtttgtg aggaatttga taatcaacta taacagttat
      241 taaatttcct aaaataagtg aaatatcaac tggaattttt tgttgaaaca cttaaacaaa
      301 tgaagcataa ataacataaa tttctgcaat caaaacaatt ccgagaacgc catctatcat
      361 caaattatac tgtatatctg tcaaaaatgt ttttgaatgt gtcaggaaat atttaatgtt
      421 ttcttttcca gtcaaaagtg taattatgat taacaaaata ggaaataaaa aaatctctac
      481 cttatttcca aaatcatctg ctatcccatt tgcaaaatga acaggaataa tctgaggtaa
      541 gaaaaacacg cttactattg ctaataaaac accaatactg caaattcccc atgttaattt
      601 tctgcttcct acaagtttca taaaaatgcc ttctttctgc aaaatttaat tttatatttt
      661 ttctcttggc tatccctatt tctccacaaa tctaataata tggacttcag tatatcatat
      721 catttatatc gcatcaacat ccaatcttgt gaggtacatt tgaaataatt ccggctaaat
      781 actccttgct gtcttgcccc ttctactctg tatcggattt ctcttgatct gcgtcttctc
      841 ttttattcct ccttttcgtt aacctgtttt tcacttcaac caaccctaca aaggcaacaa
      901 ccactgtagc catccccatt cctatccctg aagcaatatc attgatgata ttttgagcag
      961 gagataacgc ccctaccagt aaaacgccat ataccatcgc aaatagtaga gcagaaagaa
     1021 tgtctttgac cttacgttca cgaaatgtct tcttatactt ttcctcccat tcttctttca
     1081 tactttgcaa ttctactttc ccttttttcc catcctctaa taataatgta aaaggtacat
     1141 aagctccgat caaaacgcta attgttatat ttggaatttc taaagccatt ttcgaagcat
     1201 cacgacttgc aataataaat cccgatatgc aggctcccac atacgccata aaaatatagc
     1261 gttttttttc acttatcccc aaatcatttt ttttaaaaca taaagaaaac agatagtcca
     1321 tagcccaaat caaaagaagt aatagcaccg cacatatcac agcattaaaa tcagccttta
     1381 tgagtaacga aaagcatata taggcatacg atgataggag cataagaaaa acataaacaa
     1441 gttgctgtat cggcttcttt attctgttta caaattcaaa aacccaatat ttctctctat
     1501 aaatacaata aataaagcct gccgtaagta tcatactgat aatataagat attattaaaa
     1561 ctctctccat gtatttctcc tttgtaaaat ctgtttgata taacctattt cttatttaga
     1621 tagattcgtt aactatggag ggacaaaaca ttgcagctaa atatattttc taccctatat
     1681 atctcaagga atatgaaaaa tcatattccc caattattct accatccaac acacctacca
     1741 cttaggtcgt aactgtgcat tggtaatttc atcaatgatt cttcaccatg ttctgagaac
     1801 acaaccactg ctcctcttag tgaaaattca actaaaattt cctctatagt atgattccaa
     1861 acattttcaa acatttcatg caaaataata atgtctgctt cttgaagaaa tgccactaat
     1921 atttctaagc agtatctctt agatatatcc aatctgctaa ccatttcgtc tttacaatcg
     1981 gacaacttcc ccattcccag aaagccttca atcacataat ctttgtttat aattgaacct
     2041 acatttctct ctatataccg agatactgta acattatcct ctggcttcat gtttttcagt
     2101 tcaacttctt ttatgctttt tgttgttcca tagcatttta taatgtctgt tatcttacgc
     2161 tcttgtttac tactacaatt ataaaatcca actatgtctc tcgaacttat gcggaacaac
     2221 ccatcttctt catcattttt actaaacttc atttctatca tatattccct caactcctat
     2281 aagcaatggt aatttgggca tcttatattt taacaaagca taagcgattc ctgataaacc
     2341 agtcataaaa cctggattgt ataattctgt tggtaatata ttttcctcat taaggaattc
     2401 caaaatctgt tcaaatcgag aatcacaaat gcttcttacc tgcttatcat caaaaatttc
     2461 tgcatatctt tttaaaatca ataaatttcc catgtttcca tggcataggc agaaacctgc
     2521 atgtaacccg tcttcaatta atttattttt agcaaggctt atatctttaa tagcttgctg
     2581 aagcaatgca gtttctccta aattcttgat ggcattatat aaggttaatc tggataacag
     2641 aatacccgca gctccatggc accacgctat tggttgactc ttatgctgat caacctctga
     2701 aaactttctt aaatcaatcc aattattatc cttttctgag tataaagaat tttcatattc
     2761 tactaaactt gaaaggatat ctaaatattt tgtttgtgga tatacctcat ataatcttga
     2821 aaatagttct ataaaaccac tgtttccatg tgcaaatccc gccaatactt caggaaccac
     2881 ctctgatttc caaccaactt ttccattttc agtaatcata ttctctatca attgttctgc
     2941 tatttgtata gctttttgta gataaatagg cttttttgtt tttctataca tattaatcag
     3001 aaccaaaact attcccgaat ttcccgaaat catatcgaac aaacgatctt ctaagataag
     3061 tgtttccata caatttagcc acttatcgaa atattcctta tacttgatat catcatatat
     3121 ttcatataaa atacccaacg tatataaaat cgaaccttcg ccgctaaaga ttcctgtatt
     3181 aaagtcttcg atattctgtt ccccttcact tatagtatca atatacctca acaaacgatt
     3241 atctaaaacc tcacaaatct tatgatattt tctgtcatgg tatatccatt catataaatg
     3301 gaataccaaa ttaatcccaa ccgtaccatc atataatgta ttcggtaatg cctggatcat
     3361 ccactgattt tcttttatac caaataattt tacgccaatc caattaacgt ctgctccatc
     3421 ttcgctataa atcgcatttg ttcctatttt atctagcagc tcttttgcca attcttctgc
     3481 cgttttggcc atattactat aaagatctag ttttaacctt ttattcttta ttttccttgt
     3541 tcctgcattc tccatattaa aagtaatttt aatatattgc gtctgttgtt ctaaattctt
     3601 ataggacaaa ttctgtatat tttcctcaat ttgctgcaaa gctggcttac taaagaaatc
     3661 ctttacttct ctgccatccc aagtataaat gtttttttta cttccacgaa aataaaaata
     3721 cggtatatca ccacttaata aatcttcaat ttcatactca ataagagatc tactcctttg
     3781 attttgaaga tttccatttg ccaatgaata aaaaaataaa tttcgtgctc ctccatccac
     3841 taataattca ggatgatatg aactactcaa cacaattgca tactgttgtg tatttctaat
     3901 cagatatctc acctctaatt caccatattg ttgtatgatt cttaatagtg tttctgtatt
     3961 ttccattgca cctaagtatg cactttcaaa tccctggata attttatctg caaattcgga
     4021 gggttgaata aaccttcctt ttagcattgc caaattgtga tttcctttcg atactggata
     4081 atcatagaca accctcatgt taaccgactt cggattgata ataaagggga tttttatcgg
     4141 gaatttttgt ccttcttctc cactaatggc actcatattg attcctgtat ctcctgcgtt
     4201 attccatgaa taaaagggga gtattcctga atacaacacc gattttctta aaagactagc
     4261 cactttttct gctgcacttt tcccattatt ctcttctata tttcctataa atgtttccgc
     4321 atcaataata actggatatt cattgcatgc aatgagattt tcaaaatgaa tatctcctcc
     4381 ttccaaaaga taatttataa acaaaataat ccctattctt tgataatatc ttgaaagttc
     4441 ttctatagac ttacaatctc tttgtattac aatttcgcac caaccataca tttctttatc
     4501 aagtatagaa tactcataac ttcccaaatt acatattcta tagaaataat ttgtaatctc
     4561 ttgtagctta atctcatttt gcaaacttcg tggtttatat aaaattttat ctcccgatac
     4621 aaattccaca caaaatactc ttctcccttt tttatgcgaa tcagaaaaat ctgtcgaaag
     4681 atggtttacg acaaatcctt tttcagtgat attaaatttt ttcattaaaa catctgcatc
     4741 tttctcaatg cgctctatca cttctttgta aatatctatc gcattttgta taatttcatt
     4801 tatccttctt tctaacactg gataaagcga aaataaatca ttcaaatatt gtttatcctt
     4861 taaaaaatgg tcgatataat attgatactg ttcagattca tttcccctta acacgccttc
     4921 ttgtccacat atatgcattt cataaattaa agttcggata caaagattat taagcgaatt
     4981 aaacaaaaat tgctgaaaat caaatagaat cgattcattg atatatcgtc tttgtataac
     5041 tatttctcta agctgtctat ttgcctcttg cacaaaagga tcataaaatg ctccgaaaac
     5101 cattttctca ccctcatgcc taaacgcctt tttgttcaaa gacaatttca caaaatttcg
     5161 tggttgactc ttctcgtggc tactaaaagc acaattattt ataaaaccaa aaaaatactc
     5221 aaggtggttt ttctttacat attgtaatcc ttcctccttc agtattttct tccaatactc
     5281 taaagactcc atatttattt cagacggaat agcatcatac actctttcag ataaataact
     5341 agattttttc atgttatctc cctttctctt aatccaggcc ctagttctaa aatcatcttt
     5401 ggttaattag caacaagcaa gtgtaaaaat acttccgcat tcaacagaaa ttgtgcaaac
     5461 cacacctgat gaagctaaac tatcaacttt gttacttgtc aaatctgctg cttctaattc
     5521 tgtcaaaaga tctccagccg ggttgttata tttcatattt gttctgtcaa attttctcat
     5581 aatatccacc attcctttct tcagaactag ggccttttga tacctaagta tcttgatttt
     5641 tattatatcc tatctccgaa tttcgtcttt atttttggta tagattgaca ttttttcttc
     5701 ctaattggtt ttcaactgtc tttatcattt cctaaatatg ccacaacttg gcacacttct
     5761 gcgattgaag ggtaatttta cccatgttac aataggtatt gcttatagta ttcctatttt
     5821 ccccagcacc ttaatcggtg ctttttttgt acccgtaaac ctttcgctga cagtagccaa
     5881 tacttacaca gtacgtacag cgtacttccc ctaaaataaa acgtattctg tgcgtacagt
     5941 gtaagtaaaa cttcctatta tataatgaag ggagattacc atgaaaacaa gaaatgaaat
     6001 ctatcaaggg gaaggtgccc aactgctccg gttcattaca acttaccatt cgttgcaata
     6061 tgaacagatc ttacggctct tttccaaaaa cagagagtct atcaagtctc tgatcaccag
     6121 tctggtaaaa caaaaacgca ttatctatga taaggagaac gggcttctct gcgacagcca
     6181 ggaatctgca aacaatcctg attatggcat gattgcatcc ttttgggtgc ttttggactt
     6241 caaaacagcc attatgtacc atactgacgg tgaatttcct gtaaaactga actttttctc
     6301 taaagatgag tggtatgaag tcctctatgt cccccaggaa caagaatatc ttatcaatca
     6361 tgtcatggaa agccagacaa aaagcgatgc taaacggctg gtagtattag aaacggaaga
     6421 acaggctgca aaaatccata tcacaggtgt gattgccttt tgccttgtag actcctctac
     6481 cggatctgtc agctattatg caaagaaatg aggtatgtat gaacaccaaa actgtttttg
     6541 accgtttaca gagcattgat gatgaagtcc aaaaacttca caacactatt tttgcattga
     6601 aaacaacaga tattcaagcg tatgccgaca aatacgaaga gctgagtatc agtgctgccc
     6661 tacgttctga aaggattgcc tgccagctca gaaatctggt atataccaca actgatactg
     6721 gaaagaaaga ctatctgaaa caggctgcgg ctgtgcaggg aatcaaaatc tctttttcaa
     6781 atagtgttct ttccattacc atgccagggc tactgcccaa acgtaaattg cgaaccaaca
     6841 ccgcttttct acatgagcca ttaaaccttg ccttgcagac ttatgtgaca gaacattcta
     6901 ttccgttata taaaagatgt gtggtctgtt tcagtcaaat ttatgaccag agcctttctt
     6961 tacaacgaat acgtgattac gataatttgg agttcaaaca gattttagat actatcgctt
     7021 cctatgttct ggttgatgat acgggactct tttgcgactc ctatcacact acagaactgg
     7081 ggaattacga tcacaccgtt atctttgtaa tgaaaccgga aatctttcct ggctggctga
     7141 aaaatagaaa atcgtctatc aaaaccatat cggaaatttc ctgatatttt tctttctttt
     7201 tccgatatag gtaatttttc tgcaaagaag ccatattctc tgcatttttt atgcttaata
     7261 ccgcccttac tttacccaag tataggctgt cataggtaaa aatcgaactg aggtgatgct
     7321 tatttgataa aaaccgattc tataaaatat cagcttttag aaatggttgg actatgtggg
     7381 gaattccctt ccggacagct taacagattg attgagagtg attcctatgc agagaaggtg
     7441 gttacagatt taaagcagag taagcttata agaacacact ataaagatgg cctacgaggt
     7501 tatcgcctta ccaaacgggc aaaagaactg ctgctttcgc aaaatccctg tcgttttcaa
     7561 aactatttaa ccggaaatgc agaaaccaac ctcatacgta gcgaattacc aagacggctg
     7621 cgacttcatc aaaaagcaga aacctatttg acgctttctc atgccggaat cccattcttt
     7681 ccagatgaaa agccgctgct tttttctgaa tccggcgaag cggctacgtt tcctgtgcga
     7741 agccttcctc tgttttactc ttccagggaa ataaaaaatc ttggagcagc cactacaaaa
     7801 atcaaaaatt cccgttgtat aggaatcctg atggctcctc actgtgtcta tgctgtttat
     7861 aataccggaa atacacttct aaaatgggaa tacaaaacgg aagtccgact caatgctttt
     7921 ttgcagcact atcttcaagg acttccttac catggcccac ctaccgttta tgccatcatg
     7981 actggcagtg atatggatat ggctttccga ctccttacca gtaccggggg atacaaaaaa
     8041 acactgttca tgctggatac tgcgtatgaa cacttctatt tcctacccaa taacagctac
     8101 ggagaatacc tgctccgttt attggtacaa ccccagcgta tgatgcagct caatcaacta
     8161 ctactgtccg actgttttcc ccagcgtgag gatctgccaa ttgaacatga tggaatagac
     8221 agccaggaaa agcctatttt gcttgcgtat gattttgaca tgcagcgtat caaccgcttc
     8281 aatactggat taaatatata tgggctatcc gggaacctga tttgctttga ctttcagctt
     8341 ccctgcctga aaaaatacct gactgcagat atacacttct ccagcattga ttttcaaaag
     8401 tttaaaagga ggtttttcaa tgaaccgtaa atggtggaag ttcctgtttt tgcttcccat
     8461 aagcgtctgc actctatatg ccggaggata cgcagcacaa tttattaaaa actatcagga
     8521 atggacttct gccggaaact ttgccggcaa cggaacctat ccgcaagcag cttctttaca
     8581 cccattggtc tgctttcata ctgcccttat cgatttccca tacaatttgt atgggatttt
     8641 tctttgcctg gttctcttgg ggcttcttac ttttttactt atgcgtatgg gatatgacag
     8701 aaacggggag attagtgacc atgaccggaa cttaaattac tctacaaaag gaacctacgg
     8761 tacatccgga ttcatgactc cagatgaaat gatgaaagtt ttggaactga ccggagatgt
     8821 aaagaaaaat aaaggaacca ttttaggcaa attaaatggc aaagctgtat gtcttccata
     8881 taagacacga atgaataaaa atattgccgt ttatggtgcc agtggttcca tgaaatccag
     8941 ggcatttgcc aggaatatga ttttccagtg tgtcgccaga ggacaggaag gcaacaacgc
     9001 ttccggggaa agtttaatca ttaccgatcc caaaagcgaa ctctatgaaa gcatgtctgc
     9061 ttatctggaa aacgagggct atgtagtaaa agcatttaat ctggtcaatc cggaaaactc
     9121 cgatagttgg aattgtctgg gtgaaatcaa tggacaggaa acgatggctc aagtatttgc
     9181 agatgtcatt atccagaata caggttccgg aaaaggagat catttctggg ataatgcgga
     9241 gatgaacctg ctaaaagccc tggttctcta tgtggatcag ggctttccgc cggaagccag
     9301 aaatattgga caggtttata agctgctgac tatgagttcc gaaaaggagc tgaacagtct
     9361 ttttgatctg ctcccagtgt cccatccagc aaaagttcct tactgcatct acaaacaagc
     9421 cagtgatacc gtgcgaagcg gagttattat cggattgggt gccagacttc aggtatttca
     9481 gaataaactc attcggcaga ttacctctta tgatgagatt gatctgacac ttccagggaa
     9541 acagaaatgt gcttactttt gcattacctc agaccaggac agcaccttcg attttttatc
     9601 ttccctgttt atgaccttca tcttcatcaa actggtccgt tatgcagata aatatggaga
     9661 agaaggaaaa cttcctgttg ctgtacatat actggctgat gagcttgcta acaccggagc
     9721 tatcctggaa ttgaataaga agatcagtgt aatccgaagc cggaatctca gcatttcctg
     9781 catctttcag aatttacccc agatgcagaa ccgctatcct tataaccaat ggcaggaaat
     9841 tatcggcaac tgtgacaccc agctcttttt gggctgcaca gatgaagtta ctgctacctt
     9901 tatcagtaac cgcagcggcg atgtaaccgt aggggtaagc agcgaagcta agcagctcaa
     9961 tagctggcgg gtatctgact atacaccgga ataccggcag acaaaatcta tcggcaaacg
    10021 gaaactctta accccagatg aaatcttgcg gctcccgctt gatactgctt tggttatcct
    10081 acgtggacaa aaagtcctaa aagtagaaaa gtacgattat accctgcatc cagatgccca
    10141 aaagctgaca ccaagaaaag catcggaaca catacctgaa tggcgcaaaa atggttcctc
    10201 ggaagaaaca gattatcgac cacagtcctc atccggatca tccaaaagga aacgccgtcc
    10261 atcttctgca tcaatagcaa aacagaaacc acattttaca tccgaacccg tttatcagga
    10321 acctactccc gatgatttta tggaggattt ccttcaggaa aattttatag aagattcccc
    10381 cgactctggc atggttcctt tagataaaga ttccatcatg tcataacaca ttttgaaagg
    10441 agataacatt tatggcaaac gaaacaatga acctgaacac ccctatttta acccttgact
    10501 ccgatactgt attagaaact gctcaatcaa aagcggattt aatctggcat gacatccaaa
    10561 atgcctatcg tacccggaaa attctcactg gcattctagg aggtattgaa aagaccgaag
    10621 ctggcagctt aatagcaatt atttactata aggattatcg ggcaatcatc cctatctcgg
    10681 aaatgatgat caatctaatc caggatgaaa ctcatgatta cggagatctc tctcttagac
    10741 agaacaaagt ccttaataat atgcttggtt gtgaaatcga ctttgtaatc aaaggactgg
    10801 ataccaaatc cagaagcatc gttgccagcc ggaaagatgc tatgctgaag aaacgtcaga
    10861 ttttctattt tgatcaggac tcttccgggc agacaaaaat ttatgaagac cgtattgtgc
    10921 aggccagagt cattgccgtt gctgaaaaag tagtccgggc agaaatcttt ggtgtagaaa
    10981 cttccatcct tgcaagagat ctgtcttttg actggctggg tgatgccagg gaacgattcc
    11041 aggtagggga acatattctg gtccggatct taactatcca gggagattcc ccggaaacgc
    11101 tctccatcca tgcagatgta aaaagcgtgg aaggaaacac cagcaaagaa aatctgaaaa
    11161 attgtcgggt acagggaaaa tatgccggaa cggtggaaga tatccacaaa ggaacagttt
    11221 tcgtccggtt agaactgggt gtcaacgcca ttgctcacag ttgctacgac agccgcaccg
    11281 ttggaaagaa agataaggtg tcctttgttg tgacacatat tgacgaagat cggaatgttg
    11341 cagtggggat cattacaagg attattaaac agaatattta aagagatttc ttcatttcca
    11401 aaggtgagta gtgttgaact gctcacctta agtatatata tcaattttgg ataattatat
    11461 attatacaaa ctcatatttt caatctattt ttattctttc aaccaatgac actttccttt
    11521 gaagtttcaa aatagcatta accatacata tagttacaca taatactagt aatatatata
    11581 ttataatatg tggacatggt aattgataaa caaaatatga aagtccattc ttacttaatg
    11641 cctccacaag aacatatccc aatccatttc ctaatattaa tgttactgcg atactaagta
    11701 ttatcaaaag aatattttca tacataatca ttttttttaa ctgtttctta gtcattccga
    11761 tagcttctaa catggcaaac tctctgcgtc tggtagcaat agaagacata gatatacaaa
    11821 ttaaatttaa ccaactaaat ataattatga aaaatgacac ccctaaaatt tgcatacgtg
    11881 ttttctctat aatatctgca ttttccttta gtgtttcttt aagtgtttgc attaccaaat
    11941 ctggatgatt caataaaatc ttttctaatt tttgagtaac agcatcacca ttcattttat
    12001 aatcagaaac actgagaatt attgaagctg taatatccat atctccccaa aattttttta
    12061 ttgtttctgg tgttaaataa aatccttcat taaaactttt ttcagatgtt ccagcaatta
    12121 ttatattatc cgaatgttcc tgtccatcaa accatctaaa agttaaattt tctcctttaa
    12181 taggacaatt atgatacaca tccttttgga catcggttcc taatattatc ataccatttt
    12241 tttctaccaa ctcttcatat gtccattgat cgtcaagact atccaacact tccgctttat
    12301 tttcttctgt tatgggaatt attggtattt ccatatcttc tcctgcatat tctattatac
    12361 ccgccgttct tttttcaatt aatatatttt ttacattagg tatatcagct atatttttaa
    12421 tcagctcatc agaaaaagga gtttttatct gatattctga aattccatac ggctttccat
    12481 taattaaagt attatgatta atccctatat aaaattctcc ttgttctaaa tttccttgac
    12541 gtgcaaattc ttcttcactc catgaattaa gaaatgtcac tccgacaaca aaaagcactc
    12601 cactaataac tagcgaaact aatatcaaaa atttcttttt acgttctcta tatatatttt
    12661 ttttggcaag tgtaaatgct gtaagatgac tatatgattt tgaactaaag ctcttaccat
    12721 cttgaaaaga caaaaatttc acattttcta tcggtgttat actactagca attcttgaag
    12781 gagttaatat agatattcga acaactaaat accctattat cattataatt gtgcatacga
    12841 tacttatatt tacaatattc acgccgttag gttctataaa tatggcaaaa caaagtccaa
    12901 ctactacacc aatagaaatt cctaatagac tacatatatc cccttccata cgtataagcg
    12961 atttcacctg tttcttagtc attccaatca gtctcaaatt tcctatttga acaactctat
    13021 ttgaaaccga taaataaaaa atactataaa taacaattat actaacacca aatataaaaa
    13081 aactatatat aaatgtcatc ccaaaactag actcgtctcc caaagaaccc aaaaatttac
    13141 tattaaaata aatctctttt ctatcaatat catacttatc cgccatatca tatatagtat
    13201 tttcaaattc aactatattc attatttccg cattattaat tctaatgagt gccatgtatg
    13261 gaatttctgt aaatagtttt ccttcctctg catatctttg cgaaacataa aaaaagcttc
    13321 ctgtgctact tacattttca caaattccag taattataaa tttttcaaaa ataccatcat
    13381 tatttgaaac ttctaattca tcgccaatct ctttattcag aagttgtagg agattttcat
    13441 ttattactac ttcattttta tctattggtg cattaccttt taaaattcta tacgtgtgta
    13501 ttacctctgt attattgggc atataaacag cctgaatctt tttattatct attaaaattt
    13561 caaaaccact tttgtaaggg actaattcct caatcaattt atttttttgt aattcttcta
    13621 tttttgaggt agttaaattt gcaatagata cttgctgcat ttgcgacaaa actttttgtt
    13681 ctgcagtcct atttccaatt tgaatcaaaa aaagtcctgt aatcaaacta attgctataa
    13741 taatagttag tactatggca ccaaaagtta atttattatc aaaggtattt ttcctcgcaa
    13801 ttattctaag cattgatttc tctatcttct tatttttcac attcaaatga cttacctcct
    13861 ctatgctaat acaaaaccat ttaaataatc gagaaaatat gaatactaaa tccatacctt
    13921 ctcgattttc tagtatttta tcacttgatt ataatatgtg catcatttct tacttatcat
    13981 gagaaatcca tgcattttgt gtaatgcaat catgatggca atgaattttc aactgtgtgt
    14041 cacatgaaca aaaaatgttc acctcttctt ctgttaattc tggtaattcc tttgattctt
    14101 caataatttc ttttttcata gtttcgattt cctttctaaa atattgttgt ccaaaacgct
    14161 gaaccatcgt ggcaatctac tgcacatgct gtttttgcat gtgtatcgca cagaccatag
    14221 acattaattg aataatccgg tgcccgtgtc cctgctgtcc ggtgacagga aaccgcaaat
    14281 ccgtttttta ggaaaccacc attcc
//
