LOCUS       c00029_gnlPro..        16693 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJHBGNDM_29.
ACCESSION   c00029_gnlPro..
VERSION     c00029_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:51:51
            Original ID  :: gnl|Prokka|JJHBGNDM_29
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16693
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16693
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3135:6693](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3136..6693
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16693
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16693
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(563..1717)
                     /locus_tag="ctg29_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1924..3102
                     /locus_tag="ctg29_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLWKDHKVHKGD
                     KNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGFLY"
     CDS             3136..6693
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_3"
                     /sec_met_domain="PFOR_II (E-value: 1.1e-18, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.6e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.8e-31, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.3e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 5.8e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.7e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.7e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6818..7006
                     /locus_tag="ctg29_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7017..7877)
                     /locus_tag="ctg29_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7905..8735)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg29_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 6.5e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8732..9958)
                     /locus_tag="ctg29_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10431..11717
                     /locus_tag="ctg29_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11680..12012)
                     /locus_tag="ctg29_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12040..14802)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.7e-20, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWMKTMRYLKWMLVLFCLIGMTACRQDTPRFRIGVAQCSDDSWR
                     HKMNDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPI
                     VEEAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLS
                     GSTPAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHND
                     RIAPGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLA
                     MDILEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQ
                     QVVLYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQL
                     SHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNI
                     LLRLVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTD
                     YHTLADMEKLERIYFNLLSNAFKFTPENGKIAIRLSSLSKEDKRWIRFTVANTGSMISA
                     EHIRNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSC
                     EAVAAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHT
                     DYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTA
                     CSLDEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCD
                     MDKDFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARL
                     KKAASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15126..16352)
                     /locus_tag="ctg29_11"
                     /transl_table=11
                     /translation="MFFSLIVPLFLSLFYKPIAYLCGRSLNNKLKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFRELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 gtaaactaat tcagttataa caaacgaagt tgtcaactaa aaccagtaca catcatttag
       61 cagtatcttc aaagagtttc cattgcttga aaccagagtt tcatcggtgt gaaactgtag
      121 tttcatcggt gagaaactag agtttcatac gcttgaaact ttagttccaa acgctcgaaa
      181 ctatctgaaa ctactgttga tttgattgac ttaaccgcat gttccaatca cattgaacgc
      241 atcagctact tcaatagtac tgctctctct gaaaacatta aatcatatat cagtcaataa
      301 tacataaatt atcagtcctt aatacttgat ttctcaatta ttaatatctg agaaatcaaa
      361 cgttaacagt tgagatatca gatattaaca tcctgtaaat caaagaataa cacagtaaaa
      421 acggtattta tcaggacgat gcagagtgag agcaagtcct tgctctcact ctgctaccac
      481 tggatctcta acagctaaaa catcgatgaa taaagggata cagacgaact gttagagcat
      541 gagagcaaaa gcactatctt tttcactggg ggagagtaag caaaagaaac gcacgatacc
      601 ggctttgagg cgtcaccggt actaacggca aatatccggc acacacccga ttattctcta
      661 cggacaaagg gaacgaagcc gacatctgcc gatgttcctc caaagcctga ccggctaaag
      721 gataataatc aatccgaaaa actccttccg catccgcagc caaataacga tccgtcaaga
      781 gccatgccac cacccccata ttcattcgca gattaatttc gacacaagga tgaatccggt
      841 aaacaggcgc ttcatccgga aaatgacaaa tcatcatatc cactcccaag tatccatgat
      901 aaaagccacc gaacaaagct gacaattctt cttccaaacg agtccgcagc ctgataaatt
      961 cttcttgtgg cacataagcc gatagtttct gcagaatctt ctcgtcagac agcaagtcat
     1021 tccctgcata catcccactc ccacccgtgt ggaagaccga atatccggca aaaacaaccc
     1081 ttcctctccc gtcagcataa aactccatag cgaaatcttc caccttatta tatataggtt
     1141 cgcctaccac cccaccctga gaagcagcga cacgggcaca ccaaccggaa ataaaagtag
     1201 taaatatgcc tttacaccaa ttcaatcctt tcccgcttcc ggaaagcgga gcttttaaca
     1261 agcacgcttc ccgcccttcg acgaacgcac tgcactccgc caaagtactc aaataaaaag
     1321 attctccaca gaagtattca ttcaaccgca acccaggcaa caactttacc gcctgcagac
     1381 gatgcgaatg ctctctcaga atattcatat aatccgcaga aggcagctcc gtctgacctg
     1441 cccccaatgt catcaaacgc ttccgcaaag cagggtccca accccacgga gagaacttcc
     1501 agtctttacc gtcagccact tccggttccg tcaacaaggc cacatccatg cccaaaagtt
     1561 cactctttgt tttcaggaag tccgcattat aagcagacgg tgcaagcacc gcacttcccg
     1621 cttcggcata ccacatagga agcaacgcca ggtcactcgc catctgtcgg gcggaagccg
     1681 gcgccatata gttcgtctca ccgcttgcca acgccatatc atgctccgga ttgaatatat
     1741 aaacaggtct tttcgtcatg tcaaagatgg attcaacaca ttattctgca aatatataca
     1801 ggaaataatc aggaacttac acaataaaga gaaacttata aattaaagca catttttgct
     1861 atctctactt tgcaaatcct aaaaaaagca ctatatttgc cagccgaaaa acaaagaaac
     1921 gaaatggaat cattctatcg cacacacgcc tacctcgttg agcacaccaa tgcccccgtt
     1981 cgccgcgatc ttatggacga gatcgactgg agtgaccgtc tgattggtat caaagggaca
     2041 cgtggcgtag gaaaaaccac tttcctcctg cagtacgcca aagagaaatt cggcaccgac
     2101 cgttcctgtc tgttcatcaa tatgaacaac ttttatttct ccggtcacag ccttgttgac
     2161 ttcgccaacg agtttcagaa acgtggcgga aaagtactgc tgatcgacca ggtgttcaaa
     2221 catcccgaat ggagcaaaga gctacgaatg tgctatgacc gtttccccag cctgaagatt
     2281 gtcttcaccg gttcttccgt catgcgactc aaagaggaaa acctcgaatt gcgtgacatt
     2341 gcgaaaagtt ataacctgcg cggattctct ttccgtgaat ttctgaacct gcagacagga
     2401 atgaaattcc gggcatacag cctcgaagaa atcctcagta cacatgaaca gatagccaaa
     2461 ggagtacttt ccaaagtacg accgctggat tattttcagg attacctgca tcatggtttc
     2521 taccctttct tccttgaaaa acgaaatttc tcggagaatc tgctgaaaac aatgaacatg
     2581 atggtagaag tggatatcct gctgatcaaa caaattgagc tgaaatatct ttcaaagata
     2641 aaaaaattac tatatttgtt ggctgtggac ggaccgaaag ctccgaacgt gagccaactg
     2701 gcaagtgacg tacagacatc ccgcgctacg gtaatgaact atatcaagta tctggcagac
     2761 gcgcgtctga ttaatctggt ttacccgaaa ggagaagaat tcccaaagaa accgtcaaag
     2821 attatgatgc acaactctaa cctgatgtac tccatttatc cggtgaaagt ggaagaacag
     2881 gatgtactcg acacgttctt cgttaacact ttatggaaag accataaggt acataaagga
     2941 gataaaaacg tctctttcat ggtagacgaa gtgatgccgt tcaaaatttg tgcggaaggt
     3001 acaaaaataa agaataaccc ggacgtgacg tatgcgttgc aaaaggctga gataggccgc
     3061 ggcaaccaaa tacctctttg gatgttcgga ttcttatact aaaaagattt atttacttaa
     3121 atatttaatt tagttatgac taaacagaag aaattcatca catgtgatgg taaccaagct
     3181 gcagcacata tctcgtatat gttctctgaa gtagcagcta tctaccccat cactccttct
     3241 tcgactatgg ctgagtacgt agacgaatgg gctgccgcag gacgtaagaa catcttcggc
     3301 gaaacagtat tggtacagga aatgcaatct gaaggtggtg ctgccggtgc agttcacggt
     3361 tctcttcagg ctggtgcatt gactactact tacactgctt ctcagggtct tcttttgatg
     3421 atccctaaca tgtacaagat tgccggtgaa ttcttgcctt gtgtattcca cgtttctgct
     3481 cgtacactgg cttctcacgc attgtgtatc ttcggtgacc atcaggacgt aatgtcagct
     3541 cgtcaaaccg gcttcgctat gttggcagaa ggttctgtac aggaagttat ggatttggca
     3601 ggtgttgctc atctggctac tatcaaatca cgcgttccgt tcatgaactt cttcgatggt
     3661 ttccgtactt ctcacgaaat ccagaagatc gaaatgttgg aaaacgacga cctcgctccg
     3721 ctgatcgacc aggaagcttt ggctgaattc cgtgcccgtg cactgaatcc gatgaagccg
     3781 gttgcccgtg gtatggctga aaaccccgac cacttcttcc aacatcgtga atcatgcaat
     3841 aactactatg aagcagttcc tgctatcgta gaagaataca tgaacgaaat ttccaagatc
     3901 acaggccgca aatacggttt gttcgattac tacggtgcag aagatgcaga acgcgtaatt
     3961 atcgcaatgg gttctgtaac tgaagctgcc cgcgaagcta tcgaccactt ggtagcaaac
     4021 ggcgaaaaag taggtatggt tgccgtacac ttgtatcgtc cgttctctgc taaacacttc
     4081 ctggctgctg tacccaagac tgcaaagagc atcgcagtgc ttgaccgtac aaaagaaccg
     4141 ggtgctaacg gcgaacctct ttaccttgac gttaaagact gcttctatgg cgcagaaaat
     4201 gctcctgtta tcgttggcgg tcgctacggt ctgggttcaa aagataccac tccggcacag
     4261 atcatctctg tattcgaaaa cttggctatg ccaatgccga agaaccactt cactatcggt
     4321 atcgtagacg acgttacgtt cacttctctt cctcagaaag aagaaatcgc tctgggcggt
     4381 gaaggtatgt tcgaagctaa attctacggt ctgggtgctg acggtactgt aggtgccaac
     4441 aagaactctg ttaagattat cggtgacaac accgacaaac actgtcaggc ttacttctct
     4501 tacgactcca agaagtcggg tggtttcact tgttctcact tgcgtttcgg tgatactccg
     4561 atccgttcta cttacttggt aaatactccg aacttcgttg cttgtcacgt tcaggcttac
     4621 ctgcacatgt acgacgtaac acgtggtttg cgtaagaacg gttctttctt gctgaatacc
     4681 atctgggaag gcgaagaact ggctaagaac ctgcctaaca aggtgaagaa atactttgca
     4741 cagaacaaca tctctgtata ctatatcaac gcaactcaga ttgcaatgga aattggtttg
     4801 ggcaaccgta ccaatacaat ccttcagtct gcattcttcc gtatcacagg cgtaatccct
     4861 gtagatcaag ctgttgaaca gatgaagaaa ttcatcgtta agtcttacgg caagaagggt
     4921 gaagacgttg ttaacaagaa ctacgctgct gtagaccgcg gtggtgaata caagactctg
     4981 actgtcgatc ctgcttgggc taacctgccg gatgatgcaa aagcagaaaa caatgatcct
     5041 gctttcatca acgaagtagt tcgtccgatc aatgcacagg acggtgactt gctgccggta
     5101 tctgcattca agggtatcga agacggtact tggtatcaag gtacttccaa atacgaaaaa
     5161 cgtggtgtag ctgcattcgt tcccgaatgg aatgctgaaa actgtattca gtgtaacaag
     5221 tgtgcttacg tttgtcctca cgcttctatc cgtccgttcg tactcgatgc tgaagagcag
     5281 aagggtgcta agttcgagca actgaaagct gtaggtaaag cattcgatgg tatgacattc
     5341 cgtattcagg tagacgttct cgattgtctg ggttgcggta actgtgccga catctgtccg
     5401 ggtaatccga agaagggtgg caaggcattg accatgaaac accttgaaag ccagttggcc
     5461 gaagctgata actggactta ctgcgctgaa aacgtgaaga gcaaacaaca cctggtagac
     5521 atcaaggcta acgtgaagaa ctctcagttc gcaactccgt tgtttgagtt ctcaggcgct
     5581 tgctccggtt gtggtgaaac tccgtacgtg aaactgattt ctcagttgtt cggtgaccgt
     5641 gaaatggttg ctaacgctac aggatgttct tctatctact ccggttcagt tccttctact
     5701 ccgtacacta tgaacgaaaa gggtcacggt cctgcatggg ctaactcctt gttcgaagac
     5761 ttctgtgaat ttggtctggg tatggaactg gctaacgaaa agatgcgtgc ccgtctggtg
     5821 aaagtaatga acgaagctat cgcttctgat tgctgcccgg ctgaatacaa agaagtattt
     5881 gctgaatgga tcaacaatat gctggatgca gaaaagacta aggaactggc cgaaaagatc
     5941 attccgatgg tagaagctgc taaagataaa tgcaaccact gcaagcaaat cgctgatctg
     6001 caacaatatc ttgttaaacg cagccaatgg atcatcggtg gtgacggtgc ttcttatgat
     6061 atcggttacg gtggtcttga ccatgtaatc gcttccggta aggacgttaa catccttgta
     6121 ttggatactg aggtttactc taacacaggt ggtcagtctt ctaaagctac tccggtaggc
     6181 gctatcgcta agtttgctgc tgcaggtaag cgtgtacgta agaaagacct cggtctgatg
     6241 gctactactt acggttatgt atatgttgct cagattgcta tgggtgctga ccaggctcag
     6301 actctgaaag ctatccgtga agctgaagca tatccgggac catcactgat catcgcttac
     6361 gctccatgta tcaaccacgg tctgaaagcc ggtatgggta agagccagga agaagaagaa
     6421 aaggctgtta agtgcggtta ctggcacttg tggcgttaca accctgcttt ggaagaagaa
     6481 ggcaagaatc cgttccaact ggatagcaaa gaacctaact gggaagactt ccaaggtttc
     6541 ttgaagggtg aagttcgtta cgcttctgta atgaaacaat atcctgctga agctgaagaa
     6601 ctgtttaaag ctgctgaaga aaacgctaaa tggcgttaca acagctacaa acgtcttgcc
     6661 agagaaaact ggggagctga tacagctgaa taataagtag aaatactttg tacataataa
     6721 aaggcaggaa tcctggaaac agattcctgc cttttttgtt tatatcttag aagtaacgat
     6781 tacttctcac gaagatattc attaaaactc taaagatatg atcggatttg ttatttggat
     6841 tatcggtttg atactgactt tcagagctgc catagagatt tggaatataa atgcggctgt
     6901 agagaaaaga cttatagcga ttgtattaat cgttcttacc agctggctgg gactactttt
     6961 ctactacttc tatggtaaag aaagaatggc gggatggttg aagtagtgtt tgcatatcaa
     7021 tctttctcag gaatccaact gttcaccagt tcctgatgtt cttccatcca ttgacgggca
     7081 gcctgtcttt ccgttgtctg cgcctcttcc agagcagtca ttaaggagct gatttccgca
     7141 tctgtcagac gaatgttgcc caaaagttcg gcagcaaaag ggtccttctc gctaaaacct
     7201 ttccatgcta tggtatgaat ggattccgta tttccatata tcagcttcgg gtcctgaaga
     7261 actttcagct tgaaacggtc gaacatccag tgaggcgtcc atcccgtcac gacaatccag
     7321 tctttcttat caatcgcttt ctttagggaa gcagtcatgg caggtccgct cgaagtcatc
     7381 agtttataat ccaatccata gtctttgatg gcctgatcgg tagctttcat aataccggct
     7441 ccggcatcaa taccgacaat ctgaccggag aaacgttcct tttccgcgtt cagttcttcg
     7501 attgagttga tcgtaacgta atccggaacc accagcccga tacgggcacc atcataaata
     7561 tccccgataa cttcgagttt atccccgtat tgtttcatat aatcttccat agtgacaggc
     7621 atccagacat ccataaatac gtctgctttc ttacgggaga tagaggtaaa tataggtgca
     7681 aggtcggcat tcagcaactt tacatcgtac ccctgatctt caaaaatcgc tttggcaagg
     7741 tttgtcattg caataccttc cgaccagttg gcataagcga tacttatctt cttactcttt
     7801 ccgttgtctc cgcaggaaac gaaggttaag agtatgccgg caataaacat tgccgcaatc
     7861 atttttatct tattcattga ttattccttt ctttggtgtg attcttattt ctttttactt
     7921 tttctgttat ctgccatacc ctgagtgatg cggtccagca cgatcgccaa tatcacgact
     7981 gcgataccgc cttcaaatcc gagtccgatt ttcatttggg tgataccttt cagcacgatt
     8041 tctcccaatc ctccggcaga aatcatggca gcaatcacta ccatcgaaag tgacatcatg
     8101 atcgtctggt tgattcccgt cagaatagta ggcaacgcca aaggcaattg caccttataa
     8161 agaagctgcc agggagtagc tccaaaagag cgggaggctt ctactacgtt tttaggaacc
     8221 tgacgaatgc ccagaccggt cagacgaacc acaggaggca ttgcaaagat gatggtggca
     8281 aaagctcccg gcacagttcc caatccgaag aatagaacgg caggaatcag atagacaaag
     8341 gcaggcattg tctgcataaa gtcgaggaca gggcgcatta tcttgttaca acgatcactg
     8401 ttggcagtcc agattcccaa cggaacgcct aaaagcaatg ccagacaagt ggaagaaagt
     8461 accaatgcca atgtctgcat cgtttcttcc caaaagccca tgccgtaaat aagcaataaa
     8521 cccaagaggg taaatacggc tgtcccctta cccgacttaa accaggcgag cgcagccagc
     8581 actgcaattg tgatataaaa aggtattcca aacagtacgt gctgaaaacc gtctatgaat
     8641 cctccgatcc ccatgctgag agcatcaaaa aaggaagcaa aatgttctgt gagccaatta
     8701 atggcagtct ctatatattg tccgatattt atcataattc tattgcgttt tgaatgattt
     8761 cattaatttc ttctttatct tttcccgtta cttcgatgat caatgaggaa agtggcacta
     8821 cgccttcaaa ctcccgattc tcatttacga cccagattgg cgagttcgtt tttgtcatca
     8881 acggaagaat atcttccagc accgtatcac ccagcactga atgaacttca tgccttacta
     8941 cggactcgat ggagcggatt tgctcttttc gtagtttcag caagtcattc aaccgcacct
     9001 ctcctactaa cagattattg gaatcgacta ccggaagaac ggtcagattc cgttcgcgca
     9061 tcttacggat cagcacctcc gggccttctt tcttcaaacg tgccactatg ggtttatcta
     9121 ccataacaga ggaagctgtt ataatcttgc ttcgatctac attctccaca aatcgttcta
     9181 cataagcgtt ggcaggttcg gtcaggattt cttccgatgt accgatttgt acaatttctc
     9241 catccttcat gatagcaatc cggtcaccca atttaatcgc ttcactcagg tcgtgagtaa
     9301 taaagacaat cgtttttttc atcttcgact gcaaagtcag cagttcatcc tgcatctgca
     9361 cacggatcaa aggatcgagt gccgagaagg cctcatccat caacaggact tcgggattat
     9421 tggccaaagc ccgcgccagc ccgacacgct gctgcatccc acccgacagt tcacttacca
     9481 tctgattctc gtagcctttc agccccacca gttgcatact ttccatcgct ttctgctccc
     9541 gttctccctt ttttactccc tgtagttcga gcccgaaagc tatattatgc aagacagaac
     9601 ggtgaggaag cagaccgaag ttctgaaaga ccatagccag ttctttccgg cgaatctgca
     9661 acagttcctt atccgacact ttggctatgt ctgttccatt gataatcact tctccggaag
     9721 tagggcgtat caaacggttg atgcagcgga gtaaagtgga ctttccacta ccggacagcc
     9781 ccataatgac gaatatttcg ccttcattaa tggaaagatt cgcatctttc accgcaactg
     9841 tacatccggt cgctttcaat atttcacttt ttgttttacc ttctttcaac atcttcaaag
     9901 ccttctgctt ctcattgcca aaaaccagat agagatcttt aatttctatt ttactcatac
     9961 aataaaatgg tttaggttat taaaataata tacacagcaa gacaagaaca aacgataaca
    10021 ggaatctttc tttatatcgt ataaagttct gatttaaata agggacaaat aacaatgaat
    10081 cccgaaataa ttaataaaat gattattgac agactgagta attaaaaaag gaatagaatt
    10141 tgataagata atcctttcaa cgaatagcaa aaaatagcat ttttatgtat aaaaacagcc
    10201 tgttccagta tcttgctggc acaaagatac aaaaaacgga ttaaacatac aaattatatt
    10261 caaaatccgg ggcatacaga gggctttatt tgtaatgata tggaaagttt ccgggtaata
    10321 ttcccctatc actcagcaaa atagaacaaa ccggcagata aatataaaat aagtttgaat
    10381 atttcactta aacaccgtat atttggcgtc aataactaaa ctagatttat atgttcaaca
    10441 gggctattac aattttcctg gggaaggata attgtcatta cacaacaaaa gaaaaacaaa
    10501 caggtactgc cacactagac gacaaaagcc aagtacagtt ccttagtaaa aagaacccca
    10561 aaatgccgtt tttctatagc cggcggaatc tctacatgat aggtttcctg ctcgctttta
    10621 tagtgactct gctcgaattt atacgaggac ggcatcaaaa ctttatggtc ttctcggacg
    10681 ctactcaatt cttctggcaa ggcatcagcc catacacaac tgaatttgta gaagctcacg
    10741 gacgctactt cctttattct ccagttttca cggtattgtt cgctccgttt gcgtatctgc
    10801 ctgcatggct gggacctttc gcgtggaatc tattcaatta ttcgctgttc tttatggcga
    10861 tcttcacgct gccccaacaa ttcacccagc agcagaaatg ccgtatgttc ctttttctgt
    10921 tactgatttt aggacaaagt ttactttcat ttcagtataa cataacggta gcctatttat
    10981 tcttattcgc ctatacgtta ttggaaaaag accgtggatt tctggctgtt ctgttaatca
    11041 tgatttcggg atgtaccaaa gtatatggaa ttttcgaact ggcattgttg ctgtgctatc
    11101 ctcacgtatg gcgtaacttt ggctatgccg ttacaatggg cattgtattg cttgcattac
    11161 cgttaataaa aatagctcct gcagatttgc tcccctatta tgaagaatgg tgccatagtc
    11221 ttgctgttca tcagtccgcc ggagcttatg attcattttt ctatgcccgc cccattgcag
    11281 catggacatt gccacacttc cgtgcacttc agataggaat gctcggcttg ctgactctgc
    11341 tctttttggg gaatttccgc aaatggtcgt cttttgcctt ccgtgcccag gctttgggca
    11401 ttctcatggg ctgggtagta ttactgagtg actccgccga gaagcatacc tatattatcg
    11461 cattggcagg tttcatgctc tggtattgga gcagaccaac acgtaccgca acagacaaga
    11521 ttctattttg gtgctgtttt gtgctgttat gtatcgttcc tatcgacata ttcgtccctg
    11581 tacccatcag agatttcatt accaggacct tatggcttca tgtatgggtt ttctttattg
    11641 tatggatacg gatgatatgg cttaccttcc ttgcatcctt cattcatcca cgtgccacaa
    11701 atgttctttc agattaacgc atccgttagc tttgaaagaa acttcttctg ccagcaagag
    11761 ttgtttttgt tccacccaac cgggcaccag ccttccggtg gaatttacaa ctctatggca
    11821 gggaatggat aattcatccg gcacttcttt caatgcacgt cccaccatcc gcgagcattg
    11881 gggtgccccc aacagcaaag caatacctcc ataagtagat acttttccca caggtatctg
    11941 ggatacgact tcgtacactt ccttccgaaa ggattcggaa aagctctctt tatctacttt
    12001 ataatctttc atatatccct ctttacgata tcaatgaaat catcctttcc ttttcaggaa
    12061 atctgtcggg ctctctccaa actgctcttt atagcacttg gcgaaataag aaggtgaact
    12121 gaaaccgact tcataaccaa tctccgctac ggtcatgtcc gaagaagcaa gcaaagaagc
    12181 tgccttcttc aaacgggcga tacggagcaa ttcattcgga gagtagttag tcaatgattt
    12241 aatcttgcga taaagctgca cacggcttag tcccatgtct ttgcccaagt cctccacatt
    12301 caaaccggag tctcccattt tctcttcaat caatgacttg aatctttcta caaaatcctt
    12361 gtccatatcg cagacatctt cttttgccaa tgtctgcccg tcaccaaaga actgtttcag
    12421 acgacggtga gaatcgatca gattgcggac acgtgccagc aacagctgtg aactgaacgg
    12481 ctttgaaata taagaatccg caccaccgtc atatccctga atacgctgtt cgtccagtga
    12541 acacgctgtc agcagaataa ccggaatatg acaggtctgt aactcacttt tcagccggcg
    12601 gcaacattca atgccatcaa tgcccggcat catcacatca gaaatgatca ggtccggaac
    12661 atacttcata gccttacgga ttccttcgga gccgtctgcc gcttcaatca ccgtatagtc
    12721 tgtatgcaac agcgtatgga catacgaacg gatatcctca ttatcatcaa taatcagtac
    12781 ggacggtttg gaagagtcat atcctttttc cagttcttcc tcttctgcca atagaacatc
    12841 tgttgtacgg gaatccgcag aaacaagggt ggtatccggt tcggcagcaa cagcctcaca
    12901 agactgtaca ggcagttcaa cggtaaagac cgtgccctgt ttctcatcgc tctctacgga
    12961 gatcatacca ccgtgcattt ctacgaaggc ttttaccaat gccagtccga ttcccgaacc
    13021 ggtatggtgc atatcaatct tatagaaacg gtcgaataca ttgcggatat gttcggcaga
    13081 aatcatggaa ccggtatttg ccaccgtgaa acgtatccat cgcttgtcct ctttactaag
    13141 ggaagacaga cggatggcta ttttcccgtt ttccggtgta aacttaaagg cattggacag
    13201 gagattgaaa taaatacgtt ccagcttctc catgtctgcc agtgtatgat aatccgtatc
    13261 cggcatacta tcaaaagaaa aatggatatg cttcttacgg gctgccgcct gaaaggactc
    13321 attccatcct tcgaaagaag aaaggacatc caccgtaacc ggagtatatt ccatcttgcc
    13381 gttttcatat ttacggaaat ccaaaatctg attgaccagg cgcaaaagga tattcacatt
    13441 tcgctgaatc agcatgagca tccggtgctg atctccactc aatgtcttgt ccgccaataa
    13501 atgttctacc gggtcggcaa ccaatgtcaa cggagtacgg aagtcgtgag aaatattggt
    13561 gaaaaagacc agcttggcat gggtagcttc ttccagttga tgagagagct gtatcaattg
    13621 gtcacgctgt tcttccagtt tgtcacgctg ctcttccaat tgctgcttct gcttaaaaag
    13681 ctctttattc aagcgattct tagagcggag tgatttataa acgaccaata ataaaccggc
    13741 taccaataaa aggataatca gactgccgta taaaacaacc tgttgtgtag ctacctgaga
    13801 gaggtatcca ccgatacgtc cgttgagcgt ttcaatcttt ttatcgagtt cggagatgtg
    13861 tgtagtctgc aactgcatga cgtgtgcgtt ggtacggtcc acaacagcgg tattcatcac
    13921 cgtttctttg ggatagggtt tcttctccag aatgtccata gccagttgca gtaccttatc
    13981 gccattggtc ggatagataa aggtggcatc cagcacactg tccaaaacca gttccagtcc
    14041 gtttccctta cccggcaagg catctatgcc gacaaaaatc atttccttct cccgccctgc
    14101 catctttgct gcctgatagg cacccggagc gatacggtca ttatgggcat acacagcatc
    14161 aatcttagga tgcctccgaa gcatactatc catttctatc tctgccggac cacgttccca
    14221 cgcagcatcc gctttatcaa tcagctttat atccgggaat ttactgatgg cagccataaa
    14281 tccctgatgc cgttccattg caggagtcga accgctcaat cctgtcagtt ctactatatt
    14341 tcccttccct ttcagactgg aggcaatata gtttcctacc gaacgaccga tttcataatt
    14401 atcggctccg atataggcag tatatttatc cgaaagaatc ttccggtcta caagaataac
    14461 ggggatgcct ttctgataag cttcttctac aatcggagtc ataggagcag cttcgttagc
    14521 ggaaataatc agcagatcga ctccttcgtc cataaaataa tggacatctt ccgcctgctt
    14581 actgttatca tctcctgccg aacggatttc caccgaaacg ccattataaa acattgcttc
    14641 ccgaagaatc tcatcattca tcttatgtcg ccatgaatca tcgctgcatt gagccacccc
    14701 aatacgaaaa cggggtgtat cctgccggca agccgtcatc ccgattaaac aaaacagcac
    14761 cagcatccac ttcagatatc tcatcgtctt catccatctc atcatttcgt agttctttct
    14821 gtaatccaat taagaacaaa aataagaaat aatactgtaa agttctctaa cttcagctat
    14881 ttattattct aaaaagaagg aaagcagtcc tctttcagac catcggaaag tattaacaaa
    14941 agtataaagc gtaaaacaaa cacttaatca atgttataaa acatagcgtt ttacttggat
    15001 aatttgcaga tttcacagaa gtccgtatct ttgcactgtg tttttcatag tattagattt
    15061 aaggttaaca aaggttggag caaggcgttg ctcctttttt tatgccctga cctttcatct
    15121 accggttagt tttcatccca ttccttttcc agtttaccat caatagtgta gcgtttccat
    15181 cgtcctacac ggcgaccatt cttatattcc ccacattcac gaagctggtc attctttaca
    15241 taacgagctt cgaacggtcc gttctgcctt ccgttcacat aggtagaagt ttcccaataa
    15301 tcaaagcggt tgctcactat cagccgtcgt tccttgccat gcaatctgcc ggcctgatag
    15361 gtagcttcat atctcaattc accattttcc agattatatt cacggtataa accgtcttta
    15421 cgatcgttct tcatataata ttctttctgc cttaccccac ttccgttggc aaatgagaca
    15481 tggagtccat cttcttttcc atccagatag gtttcaatca tcagcgtatc tccgctttca
    15541 gcaaaagtag tccaccgacc attcttcttt ccattcttat aactacccag tatacgtggc
    15601 gagccaaacg taaacacgga cgaatattca ccgtcctgca aaccttcttc attgaaataa
    15661 acggtctcat acaaatcata tgtacctttc agaaaagtat actgtttgcc tacctgcttc
    15721 ccgtccttgt aattatgctc tttccgcaaa gtaccgtcag attcgtacga cagttgcttc
    15781 ccgtgctctt tccccatccg gaagtttctt tcactttcca cttttccggt agtaaagtaa
    15841 cttttgctcg taccgtccag cttaccttcc ttataggact tttcttcttt cagcttaccg
    15901 tcaaacttgg agttaatctt gaagaggcca tccttccgcc cttctttata acttccttcc
    15961 gttattaata tattgtccac atattctttg tatccgccat cataaaaacc atctttaaaa
    16021 gatgccagca cataggcgga atgataacca tctatgatgc gatgttcgcc attcaatgct
    16081 ttttccgttt tcagttcccg aaacaacagt ctgccatcgc ctacattgac aacggatacc
    16141 tgatcgatct tatattcctt ttgcgcaaac aaaggaagag caagatataa aaacaaaaat
    16201 acgttccagc tttttgatct gaggaagttt gaaatgtgtt tcataaagta gttttctctt
    16261 tttaatttat tatttaaaga cctgccgcaa agataggcaa tcggcttata aaacaaggaa
    16321 agaaagaggg ggacaattag agaaaagaac atctgttatt atcattctaa taattaacag
    16381 attaagtagt aaatcaaaac acagggaagg gggatattta ctgaaataag aaacagaaaa
    16441 gaagatgtgt caaaagcaac taaattcccc tccttcagga aggaggagag tttagttgct
    16501 tttgacacac cttctttttg aatttaaaga gattctacaa caatctgtct ttcagaataa
    16561 ccggaagttc gggcattgca ccgctctgcg tacaaacata agcggaaact tcgacagcca
    16621 gcttatgagc ttcgggaaca gacttgccat tcagaatgga agcacagaaa gcggcagtaa
    16681 aggaatcccc cgc
//
