LOCUS       c00056_gnlPro..        16354 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PLOKOHBI_56.
ACCESSION   c00056_gnlPro..
VERSION     c00056_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:01:23
            Original ID  :: gnl|Prokka|PLOKOHBI_56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16354
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16354
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3511:6354]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3512..6354
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..16354
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16354
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             3..149
                     /locus_tag="ctg56_1"
                     /transl_table=11
                     /translation="MPGIQLVCQRAEQGGLRGGLVYHNNLQVFNHKDTKTCRYIKAIYI
                     LIC"
     CDS             354..641
                     /locus_tag="ctg56_2"
                     /transl_table=11
                     /translation="MCIPATGIDCPHFQNAEKIHVAWGISHLLDNVPYKDGTNIKQQLI
                     GHFGKTLYYRFYREERFLSPADQNYIRQLFHRKGITEEPVFDSYTDEYNW"
     CDS             996..1664
                     /locus_tag="ctg56_3"
                     /transl_table=11
                     /translation="MEEVIRKYVDECWGFVQEHREYLMYVPSYEEHIEPEMQDTFDNII
                     PQGKSVKIYVTQPEHTNYMVDIITEKDHVWKAIDNQISDEDISKLESKLNVILPLSYKI
                     YLKYKHFYEIFWDLDVRLYPKPIHSWNKILIENNEELQEEILNKGYFAIGRYSDYGVIA
                     LKLTDDENKEGEILLFDYETPETEVLAPNFIEFLNQILQNPKPVLQELKGWEKKMYKME
                     "
     CDS             1776..2393
                     /locus_tag="ctg56_4"
                     /transl_table=11
                     /translation="MGYLPLPYNKDRNKVFYKEMDNGLIVCVGIESSSLYQDRRKTVSF
                     YTALSYTWAMYSPILLPQDCYLRIGEILGKNDLWFQTTTKEEKDFMCQSIQQAARICEK
                     QSKIILHYILKENQYVEYKEYICRLNCIIDFVKKQGITSNADISIIYEVIKPVLKRIGV
                     PLSKHTTKLYAVDAMNCIHCSSDINKQQRKIIASEIISVTNG"
     CDS             2593..2937
                     /locus_tag="ctg56_5"
                     /transl_table=11
                     /translation="LPYQYKRFLLWSNGGEGKLGDNYIYIWAIEDIVAYNNDYGIHKYL
                     QKEYLAFGMDGDIGYIFHLPNNSIYRVDLGDLDIASIKYIAPSFDDFLGKAIYLNFDKP
                     QNIVDNSSTI"
     CDS             3512..3739
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_6"
                     /sec_met_domain="Fer4_7 (E-value: 4.8e-13, bitscore: 41.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.1e-10, bitscore: 30.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.4e-08, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3e-08, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLDVIALNKEVNMKGYNYAW
                     QVKEDTCNGCSSCATVCPDGCISVYKVKVE"
     CDS             3751..4833
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_7"
                     /sec_met_domain="PFOR_II (E-value: 7.7e-28, bitscore: 88.8,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.7e-50, bitscore: 162.3,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKKVMTSSSSPGVSLKQEGISYLAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYKLIALAPASVQEMADFVALGFELAFK
                     YRNPAIILADGVIGQMMEKVVLPAQKPRRTEAEVIEQCPWAATGKAKDRKPNIITSLEL
                     KPEAMEINNLRFQAKYREIEENEVRFEEINCEDAEYLIIAFGSMARIGQKAMELAREKG
                     IKVGILRPITLWPFPTKAIAAYADKVKGMLVTELNAGQMIEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVTALKEKIIK"
     CDS             5027..5791
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.5e-26, bitscore:
                     83.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNAMHYCPGCSHGVVHKLIAEVIE
                     EMGMEDKTVGISPVGCAVFAYNYLDIDWQEAAHGRAPAVATAVKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKSSTCPYGRDVELH
                     GYPLKITEIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     SSGWKMTPEKANKWMEEHMFPFYPLGDLKDKE"
     CDS             5812..6354
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_9"
                     /sec_met_domain="POR (E-value: 3.1e-36, bitscore: 117.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDDKISSPILSKYDAAIILNQPSLEKFESKVKPGGILIYDGYGIINPPTR
                     KDIKVYRIDAMDAANEMNNAKAFNMIVLGGLLKLRPIVTLENVIKGLKKTLPERHHHLI
                     PMNEEAIKKGMELIREV"
     CDS             6464..8527
                     /locus_tag="ctg56_10"
                     /transl_table=11
                     /translation="LPPIMRRILLLYIIFSVIGLTTVHAQFDNGRQRVDENGYDQYGNQ
                     VDPAMIPDRLDSANVEVQGLPPKLYMWRINNQLGDRTIIPADTAYHHFQNSNLTEGLTG
                     HYNYLANMGSPRMSRIFFERRDPEPTIFMEPFSSFFIRPTEFNFTNSNVPYTNLTYHKA
                     GNKINGEERFKSYFSVNVNKKLAFGFNIDYLYGRGYYNNQNTAYFNAAIFGSYIGDRYQ
                     MQAIYSNNYLKTNENGGIEDDRYITAPEEMAQGQREYESTNIPTVLSATTNRNHDFYVF
                     LTQRYNLGFSRDIPQAENDTTPAKQEFVPVTSFIHTIQVERARHSFNSDDDMREKNYYQ
                     NTYLEPDNPIARDSTTYMGIKNTIGIALLEGFNKYAKAGLTAFASYKISKYTLMNMEGN
                     PLPDKYNENEIFVGGELSKREGNVLHYHAIGEVGLAGKAIGQFNVKGDIDLNFPLWKDT
                     VSLIARGEVSNKLAPFYMRHYHSKHFMWDNDMDKEFRTRIEGELSIARWRTRLKAGVEN
                     IKNYTYFNQQAVPEQKSGSIQVLSASLNQDFKLGIFHLDNEVTWQKSSDQTVLPLPDLS
                     LYHNFYMQFKLAKKVLSVQLGADVRYFSKYNAPAYMPAIQNFYLQPENDQVEIGGYPIV
                     NVYANLHLKRTRFYVMMYHVNQGMSSPNYFLSPHYPINPRVLKFGLSWNFYD"
     CDS             8563..9384
                     /locus_tag="ctg56_11"
                     /transl_table=11
                     /translation="LRLSRYLVPVIIVLAIIFSIRQCGNQEKPSGHPRDYAAIAKEGIL
                     RVATEYNSISFYVDGDTVSGFHYELIQAFAHDKGLKTEITPLMSFEERLEGLSEGRYDV
                     IACGILATSELKDSLLLTSPITLNKQVLVQRKENGENDSLYIRSQLDLAGRTLHVVKGS
                     PSILRIQNLGNEIGDTIYIKEIEKYGSEQLISMVAHGDIDYAVCDESIARTVADSIPQI
                     DINTAISFTQFYSWAVSKQSPALLDSLNAWLDKFQKEKEYQKIYKKYYDKE"
     CDS             9897..10883
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_12"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.1e-26, bitscore:
                     85.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C (E-value: 3.8e-08,
                     bitscore: 25.3, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKMIKWGFIGCGEVTKTKSGPAFQKVEHSEVVAVMSRDGAKAK
                     AYAKERGIKKWYDDAQELIDDPEVNAVYIATPPSSHATYAIMSMKAGKPAYIEKPMAVT
                     YEECTRINRISNETGVPCFVAYYRRYLPYFQKVKELVENGTIGNVINVQIRFAQPPRDL
                     DYNRDNLPWRVQADIAGGGYFYDLAPHQIDLLQDMFGCILEASGYKSNRGGLYPAEDTL
                     SACFQFDNGLVGSGSWCFVAHDSAREDRIEIIGDKGMICFSVFTYEPIGLHTEKGREEI
                     CIGNPEHVQQPLIQAVVDHLLGKSVCSCDGESATLTNWVMDKILGKL"
     CDS             11056..11508
                     /locus_tag="ctg56_13"
                     /transl_table=11
                     /translation="MRKAIELSKENVENGGGPFGAVIATKDGEIVATGVNRVTASCDPT
                     AHAEVSAIRAAAAKLGTFDLSGYEIYTSCEPCPMCLGAIYWARLDKMYYGNNKTDAKNI
                     GFDDSFIYDELQLKPEDRKLPSEILLHNEALTAFKAWVAKEDRVEY"
     CDS             11548..12357
                     /locus_tag="ctg56_14"
                     /transl_table=11
                     /translation="MKRKSLLFVMASVCLFSCQQQEELQDPSKGVIDFSTSIDQSINNA
                     LTRNSSSLTLPLKSNFAAGDVISMSVAEQDYHPFAIGMDSQTWNEAGTDSETVTFYAHY
                     PELTDEAATTRSLSSRYREIKGGLEYLFGTAQANKGSKSVALAFKRMTTPVVLLDENNQ
                     PYEGRAIVKLFLKNKGVQDLFSGKIEADPNAKPEYIDIRKVSEGILTNLIPQIIKAGEK
                     IGTVILEDGKEEPIIAEEDITIEAGTPVAVKMYARRGIIDERTPLFR"
     CDS             complement(12477..14078)
                     /locus_tag="ctg56_15"
                     /transl_table=11
                     /translation="LIMKSNRILAICILLISVGFLNAQTTIYDANRWMGSDLNGTARFV
                     GMGGAMGALGGDITTIGTNPAGIGIYRSNDVMVSFGFDNTGVKANGASLDKFHGSFDNA
                     GFVFSTKIGNTTALRFANFGFNYRKMKSFNRSMLVSGVFNTSQTVQMANMVNFDSYRDF
                     DPFTEAALRSDDAFQNPELPWLGIMGYNAHLVNPVYGKVDPENPDAVPPFEGYEPYFQA
                     GDAVSQSYRSKESGGIHSFDLNGALNFYDRFYVGATLGLYSVNYDRTSEYNEDFTDKDG
                     NGHGGYMLGNDFWVDGSGVDFKLGFILRPFESSSFRIGAAVHTPTFFSLKERNTAYINF
                     DLNETTRGITKPYDARGNDTEGEYEYKLITPWKFNASMGYTIGSSVALGVEYEYSDRTS
                     AKMKDPDGYELGQTEDIKAMMKAVHTLRVGAEFKLAPEFAFRLGYNHITAPLKSDAFKY
                     LPVNSMRTDTEFSNPGATNNYTLGCGYRGESFYVDMAYMYNTYKETFYAFDSLDLPGTK
                     VTNNNHKVVLTLGMRF"
     CDS             complement(14098..15432)
                     /locus_tag="ctg56_16"
                     /transl_table=11
                     /translation="MKKIVYFLLFALCLPIGIFAQSVDDDLYFVPSKDKQEKKETPVKK
                     EPKKQVTTNIYTSPGTTVVVQDRKGRTRDVDEYNRRYDARENEFVMDNDTLYIKEKSNP
                     DLDGEWVTGEFNGTTDDYEYAERIIRFRNPRFAISISSPLYWDVVYGPNSWDWNVYTDG
                     MYAYAFPTFSNPLWWDWRYGSYGWGWNYGWGWNRPYYSWGYYPGYWGGGYWGGWYGGGY
                     WGHHHHWHGGPSWGWGGGGRPYYAGRSVINGNNRSYYSGSRNYNSTSYRRGVGSSTTRP
                     ANSSVGQSVRRSGSTGTNSRVVGTRDYTRSGSNSSVRSGSSYSRRNTETYTRPSSTRTS
                     GTSTRNSGSSYNRSNSSTRSSGTNSSRSSSSYSRGSSTSPSRSYTPDRSSSRSSNSGSY
                     SRSSGSSYSSGSSGSYSRSSGSSGSSSRSSGGGGSSRSSGGSYRR"
     CDS             complement(15452..15646)
                     /locus_tag="ctg56_17"
                     /transl_table=11
                     /translation="MLVNNVQRYSNPGIESQVCLNFMPVSVVSSTKIVRNRDFPIILWG
                     KSPPDEKSLPYLCNVNKFK"
ORIGIN
        1 ggatgcctgg gattcagctg gtctgtcaaa gagctgaaca aggagggctg aggggtggtc
       61 ttgtttatca taataatctg caagttttca accataaaga tacaaaaact tgcagatata
      121 tcaaagcaat ttatatatta atatgttgat tattaggcgt aaaagcacat tctaaggggc
      181 gactatgtaa tatacaatat aaaatgaacg acaataaatt aaaaaacaaa acagtccctt
      241 tcaactacgc ccgctgctac aacgagcaat gtccgaaagc ttgtaactgc ctgcgtcggg
      301 tggctgcact tctcactacc gctgacacgt cctacatcag catcgtaaac ccaatgtgta
      361 ttccggccac cggcattgac tgtccccact tccaaaacgc agaaaagata catgtggcat
      421 ggggtatcag ccacctgctg gacaacgtac cttataagga cggaacaaat atcaagcaac
      481 aactgatcgg acatttcgga aaaacgcttt actatcgctt ttatcgcgaa gaacgcttcc
      541 taagccccgc agatcaaaac tatatccgcc aactttttca ccggaaaggt atcaccgaag
      601 aaccggtctt tgacagttac acggatgagt ataattggta aagccgcgtt ctaaccagtt
      661 tccagcctgc tgaaactttt tgtttcaagc gctagaaact aaaagtttca aagggtgaaa
      721 cgattcgttt cacaccgaga aacaaactgt ttcactacgg gaaaccattc gtttcaaggt
      781 atgaaacaaa aaatggaact agttaatgaa agcagaagaa gtatcagtga aggatatatc
      841 gtctaaaagt tatatgtaat acaagtgtta ttggtgaatt ttcagaatgt atgtgaaaga
      901 tcagaataaa gagttgaagt gtacagcgta aaattctcca atattgtaat caaatagaca
      961 agaacggagt gaaaaaatat ttagaaaaaa taaatatgga agaagtaata agaaaatatg
     1021 tagatgaatg ttggggcttt gtgcaagaac acagagaata tcttatgtat gtcccttctt
     1081 atgaagaaca catagagcct gaaatgcagg acacatttga taatattata ccacaaggga
     1141 aatcggttaa gatatatgtc actcaaccgg aacatactaa ttatatggtg gacattatta
     1201 cggaaaaaga ccatgtatgg aaagcgatag ataatcaaat ttcagacgag gatatttcca
     1261 aattagaaag taaattaaat gttattcttc cgctttcata taagatctac ttgaaataca
     1321 aacactttta tgaaatattt tgggatttag atgttcgtct atatccaaag cccattcatt
     1381 catggaataa aatcttaatt gaaaataatg aggaactgca agaagaaatt cttaacaaag
     1441 ggtattttgc aataggtcga tattctgatt atggcgtgat agctcttaaa ttgacagatg
     1501 atgagaataa agaaggtgaa atccttctct ttgattacga aacgcctgaa acagaagtat
     1561 tagcacccaa ctttatagaa tttcttaatc agatattaca aaatcctaaa cctgttcttc
     1621 aagaattaaa aggttgggag aaaaaaatgt ataaaatgga atgatgctac taacaagcac
     1681 ctgtaccaca taaacggcag caagccgcaa accattaccg atagtgcaat aataaaatga
     1741 aaaagaatga ttttataaat aatcaactgc tatcaatggg ctatttgcca ttgccataca
     1801 ataaagaccg caataaagtc ttttataaag aaatggataa tggcttaata gtctgtgtag
     1861 gtattgagtc ttcttctttg tatcaagaca gaagaaaaac tgtttcattt tatacagcat
     1921 tgtcatatac atgggcgatg tattcaccta tattattgcc acaggattgt tacttacgaa
     1981 taggtgaaat attgggtaag aatgatttgt ggtttcaaac taccacaaaa gaagaaaaag
     2041 attttatgtg ccaatcgata cagcaagcgg caagaatctg cgaaaagcaa agtaaaatca
     2101 tattgcacta tatcttaaaa gaaaatcaat atgtggagta taaagaatat atatgcagat
     2161 tgaactgcat aatagatttt gttaaaaagc agggaatcac cagtaatgca gatataagta
     2221 tcatttatga agtgattaaa ccagtattaa aaagaatagg tgtaccgctt tccaagcata
     2281 ctacaaaact atatgcagtg gatgccatga attgcatcca ctgctcttcg gacataaata
     2341 agcaacaaag aaaaataata gcaagcgaaa taatatcagt aacaaacggg taaattgtcc
     2401 taaaagaaat gatccgtctg agattaacat ttatcaaaat aaaaaaataa acgaggaaac
     2461 agcagttagc tgaaacacat taacagtagt acaacaaaat caatatggaa gtaatagaaa
     2521 gtaaatggta taataaagaa tggtgcaaat acagcgtcta ttgaagacgt agaaaaactt
     2581 ctaaatacaa ccttgcccta tcagtacaaa agatttctgt tatggagcaa tggtggcgag
     2641 ggtaaattag gagataacta catctatata tgggctattg aagatattgt tgcttacaat
     2701 aatgactatg gaatacacaa atatcttcaa aaagagtatt tagcatttgg catggatggt
     2761 gatattggat atattttcca cctgccaaac aatagtatat atagggtaga tttaggagat
     2821 ttagatatag cttctattaa gtatatagca ccctcttttg acgacttttt aggcaaggct
     2881 atttatctta atttcgataa gccacagaat attgttgaca atagttcaac catataaagt
     2941 gattagacat ggatataaat aatgaataaa ctacaactcc aaaaacaata ataactcctg
     3001 attcatatcg ttttttgatt aataaagtta cggatatgtc aagaaaaagg caaattccac
     3061 ctctactata caatatgcaa taaactcaaa acgttgcaaa tttccgtcct catttgccct
     3121 gtttacataa ataaaaacta tctttgcgtt tcagaatccc gaaagacgaa aagaaatgga
     3181 gcaaatagac aacctaaaag agcttatcaa tcagggggat gtggacacag cgattaagca
     3241 attggaccag cttctccagg acagttctgt cgaaaaagag aaagatactc tttactattt
     3301 acggggaaat gcctaccgaa agaaaggaga ttggaagcgg gcactggaca actaccagta
     3361 tgccatcgag ctcaatccgg acagtcctgc cgttcaggcc aggaagatgg taatagatat
     3421 cctcaacttc taccacaagg atatgttcaa tcaataaaag agatgtataa tcaataaccg
     3481 tactcaaaga taacgtaata aaataaagat tatggcaaaa atcaaaggag caatcgtagt
     3541 cgacacggag cgttgcaaag gatgcaacct gtgtgtagtg gcgtgtccgc tcgatgtaat
     3601 cgccctcaat aaagaggtaa acatgaaagg ctataactat gcctggcaag tgaaggaaga
     3661 tacctgtaac ggatgcagct cgtgtgcaac ggtttgtccg gacggatgta tttcagtgta
     3721 taaagtaaaa gtagaataaa agaaaagaat atggcagaag aagttgtatt aatgaaagga
     3781 aacgaagcca tcgcccacgc agctatccgt tgcggtgccg acggatactt cggttatcct
     3841 attactcccc aatcggaagt gttggaaacg cttgccgaac tgaaaccgtg ggaaacaacc
     3901 ggcatggtag tactccaggc ggaaagtgaa gtggcagcta tcaatatggt atatggaggt
     3961 gcaggtagcg gaaagaaggt aatgacctca tcttcaagtc cgggtgtgag cttgaaacaa
     4021 gaaggaatct cttatttggc cggtgccgaa cttccttgtc tgattgtgaa tgtaatgcgt
     4081 ggcggtcccg gattgggaac tatccaacct agccaggctg actacttcca gacagtgaaa
     4141 ggtggtggtc atggagacta caaactgatt gccctcgctc cggcatccgt acaggaaatg
     4201 gcggatttcg tagcattagg attcgaactg gccttcaaat accgtaatcc ggctattatc
     4261 cttgccgacg gtgtgatcgg tcagatgatg gaaaaggttg ttcttcctgc acaaaagcca
     4321 cgccgcacgg aagcagaagt aattgaacaa tgtccatggg ctgctaccgg aaaagcaaaa
     4381 gaccgcaaac ctaatattat cacttccctt gaattgaaac cggaagcaat ggaaatcaac
     4441 aacctccgtt ttcaagctaa atatcgtgaa attgaagaaa atgaagtacg cttcgaagag
     4501 atcaactgcg aagatgcaga gtatttgatt atcgctttcg gttcaatggc acgtattggc
     4561 cagaaagcaa tggaactagc ccgtgaaaaa ggaattaaag taggtatcct tcgcccgatt
     4621 acactgtggc cgttcccaac caaagcgatt gctgcatacg ctgataaagt aaaaggtatg
     4681 ctcgttacgg aactaaatgc cggacagatg attgaagatg tccgtctcgc tgttaacggt
     4741 aaagtaaagg tagaacattt cggacgtcta ggtggcatcg ttcccgatcc ggatgaaatt
     4801 gtaactgcct tgaaagaaaa aataatcaaa taacgaaaca atgaatcccg ataaaataag
     4861 aaacgtactg aacatcctat ttatgatatt ggctgttgca gccatcatca cctactttgt
     4921 agcaaaagat gatttcaaaa tgtttatcta cgtatgcggc gcggcaatct ttgtcaagct
     4981 gatggagttt tttatacggt tcaccaacag ataaggagat gaagttatga ctaaagaaga
     5041 aataatcaaa cccgagaatc tggtttacaa aaaaccgact ctgatgaacg ataacgccat
     5101 gcactactgc ccgggttgca gtcacggtgt ggtacacaaa ctcattgccg aagtcattga
     5161 ggaaatgggt atggaagata aaactgtggg aatctctccg gtgggatgtg cagtgtttgc
     5221 ctacaactat ctcgatattg actggcaaga agcagcacac ggacgtgctc ctgctgtggc
     5281 gactgctgtg aaacgcctgt ggccggaccg tcttgttttc acttatcagg gcgacggtga
     5341 cttggcttgt atcggtacag ccgaaacaat ccacgctttg aaccgtggtg agaatatcac
     5401 gattatcttt atcaataatg cgatctacgg tatgacaggc ggccagatgg ctccgactac
     5461 actagtaggc atgaagagtt cgacttgtcc ttacggacgt gacgttgaac ttcacggcta
     5521 tccattgaag attactgaaa tcgcagccca actggaagga actgcttacg taacccgtca
     5581 gtccgtacaa tccgtaccgg ctatccgcaa ggcaaagaaa gcaatccgca aggcttttga
     5641 gaattccatg aacggtaaag gttccaacct ggtagaaatc gtttccactt gtagttcagg
     5701 ctggaagatg actccggaga aggcgaacaa atggatggaa gaacacatgt tcccattcta
     5761 tccgctgggt gatttaaaag ataaagaata acgctaaaag tcaacagaac aatgaaagaa
     5821 gaaataatta tagcaggatt cggtggacaa ggcgtattgt ctatgggtaa gattctggca
     5881 tattccggtt tgatggaagg caaagaagtg acctggatgc ccgcttatgg tcccgaacaa
     5941 cgaggtggaa cagccaacgt tacagttatt gtaagcgatg acaaaatttc ctcaccgatt
     6001 cttagtaaat acgacgctgc catcattctg aatcagcctt cactcgaaaa gtttgaaagc
     6061 aaagtgaaac ccggcggtat cctgatttat gacggttacg gaattatcaa ccctcctacc
     6121 cgtaaggata ttaaggtata tcgtatcgac gcaatggatg cagccaacga gatgaacaat
     6181 gccaaagcat tcaacatgat cgtacttggc ggattattga agcttcgccc catcgtaacg
     6241 ttggagaatg ttatcaaagg acttaagaaa accctgccgg aacgccacca tcacctgatt
     6301 cctatgaacg aggaagctat caaaaaaggt atggagttaa tccgtgaggt ttaattaaca
     6361 gataatgtac aatggataat tgataattat tagctacgta tagtacgtat gcaacataat
     6421 tttcaattat ccattatcat taaatcaatt aaagtaagta tctttgcctc caattatgag
     6481 acgaatctta ctattatata taatcttttc cgttataggt ttgacaactg tccatgcaca
     6541 gttcgataat ggtcgccaga gagtggacga aaacggatac gaccaatacg gtaaccaggt
     6601 ggaccctgcc atgattccgg acagactgga tagtgcaaat gtagaagtac aggggttacc
     6661 tccgaaatta tatatgtggc gtattaataa tcagttgggc gaccggacta tcatcccggc
     6721 ggatactgct tatcaccact tccagaattc aaatcttacc gaaggactta ccggacatta
     6781 taattatctg gccaatatgg gttctccccg tatgtcacgc atcttctttg aacgtcgtga
     6841 tccggaacct actatcttta tggagccttt ctccagtttc tttattcgtc ctacggagtt
     6901 caatttcacc aatagtaacg taccttatac caatctgacg tatcataaag ccggtaataa
     6961 aataaacgga gaagaacgct ttaagtctta tttctctgtc aatgtaaaca agaagctggc
     7021 tttcggtttt aacatagatt acttgtacgg acgaggatat tataataacc agaatacggc
     7081 ttatttcaat gcggcaattt tcggtagtta tattggcgac cgctatcaga tgcaggcaat
     7141 atacagcaac aattacctca agacaaatga aaacggaggt attgaggacg accgatacat
     7201 cactgcgcct gaagagatgg cacaagggca aagggaatat gaatcaacca atatcccgac
     7261 cgtactaagt gcaacaacca accgtaatca tgacttttat gtattcctga cccaacgtta
     7321 caatttggga ttcagccgtg acataccgca ggccgaaaat gacactactc ccgccaaaca
     7381 agagtttgtg ccggtcacta gttttataca taccattcag gtagagcgtg cacgtcatag
     7441 cttcaactct gatgatgaca tgcgtgaaaa gaactattat caaaacacct atttggaacc
     7501 ggataatccg attgccagag acagtactac ctacatgggt atcaagaata ccataggtat
     7561 tgctctactc gaaggattca ataaatatgc caaagcgggt ctgacagcat tcgcttccta
     7621 taaaatcagc aagtatactc ttatgaatat ggagggtaat ccgttgcccg acaaatacaa
     7681 tgaaaatgaa atatttgttg gaggcgaatt atccaaacgt gaaggaaatg tacttcatta
     7741 ccatgccatt ggtgaagtgg gactcgccgg aaaagcaatc ggacaattca atgtgaaagg
     7801 agatatcgac cttaactttc cgttatggaa agacactgtg agccttatag cccgtggtga
     7861 agtcagcaat aagcttgcgc ctttctatat gcgtcattat cattccaaac acttcatgtg
     7921 ggacaatgat atggacaaag aatttcgtac ccgtattgaa ggagaattaa gcattgcacg
     7981 ttggagaaca cgtttaaagg cgggagttga aaacataaag aactacactt atttcaacca
     8041 acaagcagtg ccggaacaga aaagcggaag tatacaggtg ttgtcagcaa gtcttaatca
     8101 ggacttcaag ctgggaatct tccatttaga taatgaagta acttggcaaa agtccagcga
     8161 ccagaccgtg cttccgttgc ctgatctatc gttgtatcac aacttctata tgcagttcaa
     8221 gctggcaaag aaagtactta gtgtacaatt gggtgccgac gtgcgttatt tcagcaaata
     8281 caatgcaccc gcttatatgc cggctatcca aaacttctat ttgcaaccgg aaaatgacca
     8341 ggtagagata ggaggttatc cgatcgtgaa tgtatacgca aacttacatc taaagcgtac
     8401 acgtttctat gtaatgatgt atcacgtgaa tcaaggtatg agcagcccga attacttctt
     8461 gtctcctcac taccctatca acccgcgtgt actgaaattc ggtctttcat ggaatttcta
     8521 tgattaacaa aatctatatg gcttatggta acacgcccca aattgagact gtcccgatat
     8581 ttagtgcccg taatcattgt attggcaatc atcttttcta tccgccaatg cggtaatcaa
     8641 gaaaagccgt caggacaccc gcgtgattat gcagccattg ccaaagaagg tatattgcgt
     8701 gtagcgactg aatataactc gatcagtttc tacgtggacg gtgataccgt ttccggtttt
     8761 cattacgaac tgatacaggc ttttgcccat gacaagggat taaagaccga aataacaccc
     8821 ctgatgagtt tcgaagaacg gctggaagga ttaagcgagg gacgttacga cgtaattgcc
     8881 tgcggtatat tagctaccag cgaactgaaa gactctctgc tcctcacctc tcccatcacg
     8941 ctcaacaagc aagtgctcgt gcaacggaaa gaaaacggag aaaacgactc actctatatc
     9001 cgtagccagc tggacttggc cgggcggaca cttcacgtag taaaagggtc tccttctatt
     9061 ctgcgtattc agaatctagg taatgaaatc ggcgatacca tttatatcaa agaaatagag
     9121 aaatacggtt ccgaacaatt aatctcaatg gtagctcatg gggatatcga ctatgccgtt
     9181 tgtgacgaaa gcatcgcacg cacggtcgcc gattccatcc cgcagataga tataaataca
     9241 gccatcagct ttacacaatt ctactcatgg gcagtcagca aacaatcacc cgctttactc
     9301 gatagtttga atgcatggct ggataaattc caaaaggaga aagaatacca gaagatttat
     9361 aaaaagtact atgataaaga ataaccttat cattttacag atcagaagaa aacaatcaaa
     9421 aacagaatgt aagatagata tattcatgtc tatttccaga aataaactcc caaagacttg
     9481 actttcgctt tcgaatgtcg tatctttaca gagttaatga taaagtagtt tcaattaaac
     9541 tacatgcaaa ggagggaatc gcgattctct cctttctttt tatccagccg ggaaaaacct
     9601 ctccccgccc ccgcttttcc ttgcgctttg cccggtggtt atggttcttc agccggagga
     9661 tcagcagtgt tcaccttgct tcttaccgaa atgaagtata tatccgcctc aaacagacgt
     9721 tctgtttgcc tgaaacagag cctctgttcc gataaaacag agcttctgtt gaaacaaaac
     9781 gcaatgtctg ttttccaact gtccctgcta agttaataat caataaagtt gctcttgaca
     9841 aaaaatagct ttatctttgg ggtttgttag aacagacaca ataggtatat tatattatga
     9901 gtgaaaagat gatcaaatgg ggcttcattg gttgcggaga agtaaccaag acgaaaagcg
     9961 gtcccgcttt ccagaaagta gaacattcgg aagtcgtagc cgtgatgagt cgtgacggcg
    10021 cgaaagcgaa agcgtatgcc aaagagagag gaatcaagaa atggtatgac gatgcacagg
    10081 agctgataga tgatccggaa gtaaacgctg tctatatcgc cactcctcct tcttcacacg
    10141 ctacgtatgc cattatgtcc atgaaagcgg gtaaaccggc ctatattgag aagccaatgg
    10201 cggtgacgta tgaagaatgt acccgaatca accgcatatc caatgaaacg ggggttccct
    10261 gtttcgtagc atactaccga cgttatcttc cctatttcca gaaagtaaag gaattagtag
    10321 agaacggaac gatcggcaac gttatcaatg tacagattcg ttttgcccag ccgccacgcg
    10381 atctggatta caatcgtgat aatcttccct ggcgtgtgca ggctgatatt gccggaggcg
    10441 gctacttcta cgaccttgct ccgcatcaga ttgatttgtt gcaggatatg ttcggttgta
    10501 tcctcgaagc aagcggttac aagagtaatc gcggcggact ttatcctgcc gaagatacat
    10561 taagcgcctg tttccaattt gacaacggac tggtgggtag tggttcctgg tgcttcgtag
    10621 cccatgattc tgcccgcgaa gaccgcatag agattatcgg tgacaaagga atgatttgct
    10681 tctctgtctt tacttacgaa cctatcggac tacataccga gaaaggacgg gaagaaatct
    10741 gtatcggtaa cccggaacac gtgcaacagc ctcttatcca agcagtagta gaccacttat
    10801 tgggtaagtc ggtttgctct tgcgacggcg aaagcgcaac gttgactaac tgggtaatgg
    10861 acaagatctt aggtaagcta taaccctaaa aaaagcaaaa aaaagttcct tcttttccgg
    10921 attctgccag tattgttaag aaattaatag ggacattcca ttgtatattg ttagtttttt
    10981 ctatctttgt agaaagaagc aaagaaaaaa tgaaactaac aatatatttt ttgtgccatg
    11041 actaaagaag ctttaatgag aaaagcgatc gagctttcaa aagaaaatgt tgaaaatggt
    11101 ggaggtcctt tcggtgctgt gattgccacg aaagacggag aaatagttgc aacaggagtt
    11161 aatcgcgtca ctgcatcttg tgaccctacg gctcacgccg aggtaagcgc catacgtgcc
    11221 gcagctgcca aactcggaac atttgatctt agcggatacg aaatctatac ttcctgcgaa
    11281 ccttgcccca tgtgcctagg tgctatttat tgggcacgcc tggataagat gtactatgga
    11341 aacaacaaga ccgatgccaa aaacatcggc ttcgacgact cttttatcta tgacgaactg
    11401 caactgaaac ctgaagacag aaagctgcct tccgaaatcc tactacataa tgaagccctt
    11461 actgccttca aagcctgggt ggccaaagaa gacagagtag aatattagaa aacctctcac
    11521 tattattaac ctattaatta ccctcaaatg aaaagaaaaa gccttttatt tgttatggca
    11581 tcagtatgcc tgttcagttg tcaacagcaa gaagaactgc aagatcccag taaaggagtg
    11641 atcgactttt ctacttctat tgaccaaagt atcaacaatg ctcttactcg taacagcagt
    11701 agtctgacac ttccgttaaa gagcaacttc gctgccggag atgttatctc catgtccgtt
    11761 gccgagcaag attatcatcc gtttgccata ggcatggata gccagacttg gaacgaagca
    11821 ggcaccgatt cggaaacggt tactttctat gctcattatc ctgaattgac cgacgaagct
    11881 gctactacca gatcattgag cagccgctat cgtgaaatca agggtggctt agaatatttg
    11941 ttcggtacag cccaagccaa caaaggttct aagagcgttg ctcttgcatt taagagaatg
    12001 acaacgcccg tcgttctgct tgacgagaac aaccagccgt acgaaggtag agcaatcgtt
    12061 aaactgttct tgaagaacaa aggtgtgcaa gacctgttca gcggtaaaat cgaagctgac
    12121 cccaatgcaa aaccggaata cattgatatc cggaaagtat ctgaaggtat cttgactaac
    12181 ttgattccgc agatcatcaa agccggcgag aaaataggaa cggttattct ggaggacggt
    12241 aaagaagaac ctatcatcgc agaggaggac attaccatag aagccggaac tcctgtagcg
    12301 gtaaaaatgt acgcaagacg cggaatcatt gacgaacgaa ctccactatt cagataagac
    12361 tgaagaataa aaagtgatac taataaaaat ccccggaacc gctgtagaca ctcagcattc
    12421 cagggatttt ttacacacaa aagttattat tgaaattgaa aactgtcttt tttaggttag
    12481 aaacgcatac ctaaagtaag aaccacttta tggttgttgt tcgtcacttt cgttccaggt
    12541 aaatctaaac tatcaaaagc atagaatgtt tctttataag tattatacat atatgccatg
    12601 tctacataga aactttcacc acgatagcca caacccaatg tataattatt agtagcaccc
    12661 ggattagaaa attccgtatc agtacgcatt gaatttacag gaagatactt aaaagcatct
    12721 gatttcaaag gagcagtaat atgattatat cctaaacgga atgcaaattc cggtgctaac
    12781 ttaaattcag ctccaacacg aagtgtatga actgctttca tcattgcttt aatgtcttct
    12841 gtctgaccta attcatatcc gtccggatct ttcattttag ctgaagtacg gtctgaatat
    12901 tcatactcaa ctcccaatgc tacagaagaa ccgatggtat atcccatact tgcattaaac
    12961 ttccacggag taattaactt atattcatat tctccttcag tatcatttcc acgggcatca
    13021 taaggtttgg taatgccacg tgtagtctca ttcaaatcaa aattaatata agcagtattc
    13081 cgttccttca aactaaagaa agtcggagta tgtacagcag caccaatacg gaatgaggat
    13141 gactcaaaag gacgaagaat aaaacctagt ttaaaatcaa ctccactacc atctacccaa
    13201 aagtcatttc ccaacatata tcctccatga ccatttccgt ccttatcagt aaagtcttca
    13261 ttatattcac tagtcctgtc atagtttaca ctataaagtc ctaatgttgc tccaacataa
    13321 aaacgatcat aaaaattcag cgcaccattc aaatcaaaag aatggatacc tccactttct
    13381 ttcgaacgat aagactggct cacagcatct cctgcctgaa aatagggttc atatccctca
    13441 aaaggaggaa ctgcatctgg attctctgga tctactttcc cataaacagg attcactaaa
    13501 tgtgcattat atcccataat acccaaccaa ggcaattcag gattctgaaa agcatcatcg
    13561 ctcctcaaag cagcttctgt gaacggatca aagtctctgt atgaatcaaa gttcaccata
    13621 ttagccatct gaactgtttg agaagtattg aatactccac tcaccagcat acttctattg
    13681 aaggacttca ttttgcgata attgaaacca aagttggcaa atctcaaagc agttgtattt
    13741 cctatttttg tagagaatac aaatccggca ttatcaaatg agccatgaaa cttatcaaga
    13801 cttgccccat tcgctttcac tcctgtatta tcaaagccaa atgaaaccat aacatcattg
    13861 ctacgataaa ttccgatacc ggcaggatta gttcctatag tggttatatc tccgcctaaa
    13921 gctcccatgg caccgcccat acctacaaag cgggcagttc catttaaatc acttcccatc
    13981 catcgatttg catcatagat agttgtttga gcatttagaa atcctacact tatcaaaaga
    14041 atacaaatcg ctaatattct attacttttc ataatcaatc tcttttgaaa ttataaacta
    14101 tcttctatag ctaccaccag aactacgtga agaaccacca ccgccgctac tacgtgaaga
    14161 actgccactg ctgccagaac tacgagaata actaccgcta ctacctgatg aatagctact
    14221 tccactactt cttgaataac tacctgaatt agaagagcgg gatgatgatc tgtcaggcgt
    14281 ataacttctt gatggagaag tggaacttcc acgtgaatag ctactactgc tacggctact
    14341 atttgttccg gaacttcgtg tcgaactatt acttctatta taagaggaac cagaattgcg
    14401 tgtactagta ccagaagtac gtgtactgct tggacgtgta tacgtttctg tatttctacg
    14461 agagtatgaa cttcctgaac gaacagagct attgctaccg ctacgagtat aatcgcgagt
    14521 acctacaact ctactatttg tacctgtact acctgaacgg cgaacacttt gtccaacaga
    14581 agaattagct ggtctggtag ttgatgaacc gacacctctt ctgtaagaag tagaattata
    14641 atttctcgaa ccagaataat aggaacgatt attaccatta atcacactac gtccggcata
    14701 ataaggtctt ccacctccgc cccagcccca gctaggacca ccgtgccagt ggtgatgatg
    14761 tccccaatat ccgccgccat accagccacc ccagtagccg cctccccaat aaccggggta
    14821 atatccccaa gagtaataag gacgattcca tccccagcca tagttccatc cccagccgta
    14881 agagccataa cgccaatccc accaaagcgg gttactgaac gtcgggaatg cataagcata
    14941 cataccatcg gtatatacgt tccaatccca tgagttcgga ccgtaaacta catcccagta
    15001 caacgggctg ctgatactga tagcaaaacg cggattgcgg aaacggatga tacgttcagc
    15061 gtattcatag tcgtctgttg taccattgaa ttcgcccgtc acccattctc cgtccaaatc
    15121 cggattagat ttttctttta tatataaggt atcattatcc attacgaatt cattttcacg
    15181 tgcatcgtaa cggcggttat attcatccac atcccgtgtt cttcccttac ggtcctgaac
    15241 aaccactgta gtacccggtg aagtatagat gttagtcgtc acctgtttct tcggttcctt
    15301 cttaactgga gtttctttct tctcctgttt gtctttggaa ggtacgaagt aaaggtcgtc
    15361 atcaacgctt tgtgcaaaga tacctatcgg aaggcacaag gcaaatagca agaaataaac
    15421 aatctttttc atatcatctc ggtttatgta attacttaaa cttattcacg ttacaaagat
    15481 aaggaagaga tttttcgtcc gggggagatt ttccccaaag gataataggg aaatccctat
    15541 ttctaactat ctttgtagaa gatacaacgc tcaccggcat aaagttcagg caaacttgac
    15601 tttctatacc cggattgctg tatctttgca cattattcac cagcattaaa aacaactatg
    15661 aagtattttg agttcacatt ccgcacccag ccttgtaccg aaaccgtcaa tgacgtactg
    15721 gctgccatat tgggtgaagt cggatttgaa agttttgttg agtgtgaagg cggactgacc
    15781 gcatatatcc aacagacatt gtgtgatgaa aacgccatca agattgccat caacgagttc
    15841 cccctacccg atacggatat tacttataca tataccgaag cggaagacaa ggactggaac
    15901 gaggaatggg aaaagaattt cttccaaccc atcattatcg gaaaccgatg tgtgatccac
    15961 agcactttcc accaagatgt ccccaaagcg gaatatgaca tcgtcatcaa tcctcaaatg
    16021 gccttcggaa caggacacca cgaaactacc agcctcatca ttgaagaatt attggacagc
    16081 gaactgaaag ataaatccct gctcgatatg ggctgcggaa cttcgattct tgccatcctc
    16141 gcacgtatgc ggggcgcacg tccctgtacg gccatcgaca ttgatgaatg gtgcgtacga
    16201 aactccatcg aaaacatcga gttgaaccac gtagacgata ttgccgtatc acaaggagat
    16261 gcctcgtcgc ttgtaggaaa aggacctttc gacgttatca tcgccaacat caaccggaat
    16321 atattactga atgatatgaa gcaatatgtt gcct
//
