LOCUS       gnlProkkaBJEJHOAE_47   13649 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BJEJHOAE_47.
ACCESSION   gnlProkkaBJEJHOAE_47
VERSION     gnlProkkaBJEJHOAE_47
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:33:39
            Original ID  :: gnl|Prokka|BJEJHOAE_47
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13649
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..126)
                     /locus_tag="ctg47_1"
                     /transl_table=11
                     /translation="MQHHYELTFISPEKDFWFFVKFGGNLFFISTVSLFFFLNPIK"
     protocluster    1..13649
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3298:3649]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3299..3649
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13649
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13649
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             308..1819
                     /locus_tag="ctg47_2"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPITSIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYST
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWQLVSE"
     CDS             1893..2960
                     /locus_tag="ctg47_3"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVSKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             2996..3280
                     /locus_tag="ctg47_4"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3299..3649)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_5"
                     /sec_met_domain="PqqD_RRE (E-value: 6.9e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.5e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(3747..5135)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91; E-value: 1e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg47_6"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPTPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5384..5779)
                     /locus_tag="ctg47_7"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPAAETPAPAAE"
     CDS             complement(5786..6559)
                     /locus_tag="ctg47_8"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6565..7092)
                     /locus_tag="ctg47_9"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7079..8320)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg47_10"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8330..9424)
                     /locus_tag="ctg47_11"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9429..10469)
                     /locus_tag="ctg47_12"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(10488..11498)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_13"
                     /sec_met_domain="PF04055 (E-value: 8.8e-18, bitscore: 57.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
ORIGIN
        1 ttttatagga ttaagaaaga agaagaggga aaccgtcgaa ataaaaaaga gattaccacc
       61 aaatttgacg aagaaccaga aatctttttc aggagaaata aaagtaagtt cataatggtg
      121 ctgcattgaa ttattttttg gcggagttat tctaacactt aatagttcaa aaacagatat
      181 ttctctgacc aaaagataga actaatgatg aattaaaagt tgcaattatg gttttcttcc
      241 cacaacaaac gggaaaagtc agaagaatca tgtacatttg taatccgaaa actaaaagaa
      301 catcgcaatg aaaatatttc caagcagcag tatcaagaaa ttggacgctt ataccattga
      361 gaacgaacct attacatcaa tcgatctgat ggaacgtgca gcaaccgtat taacaaaagc
      421 catcacagac agatggaata cggaaacgcc ggtcactatc tttgccggac cggggaataa
      481 tggcggagac gctctcgccg tagcccgcat gatggctgaa aaaggatata aaatcgaggt
      541 atttctcttc aacacgaaag gagaactttc acccgactgc caaaccaata aagaactggt
      601 agaaatgatg gaagaagtaa aattccacga aatcagtacc caattcgtac ctcccgtcct
      661 gacgcccgac catctggtaa tcgacggatt attcggttca ggcctgaaca aaccgttaag
      721 cggcggattc gctgccgtag tgaaatacat caattcctcc cctgctatgg tagtagccat
      781 cgacattcct tccggactga tgggagaaga aaacacattc aacgtaaaag ctaatattat
      841 ccgtgccgac gtaactttca gtctgcaact gccgaagctc gcctttcttt tcgcagagaa
      901 cacggaattt gtcggagaat gggaagtgct ggacatccaa ttaagcgaag acggtattga
      961 agagatggaa acgaactacg aaatgttgga aatagagcaa atccgttcac tcatcaagcc
     1021 acgcaaacag tttgcccaca aggggaactt cggccatgca ctattgattg ccggttcaaa
     1081 aggaatggca ggagcctctg ttctcgctgc ccgcgcctgc ctccgttcgg gagtagggtt
     1141 gctgactgtc catgcgccaa tgtgcaacaa cgacatcttg caaacctcca tacccgaagc
     1201 aatcgtagaa accgacatca acgaaacctg ttttgccgta cctaccgaca cggacgacta
     1261 tcaagcagtc ggcatcggcc cagggctggg acgaaacgag gaaacggaag ctgctttatt
     1321 ggagcaactg gaacattgcc agactcctgt tgtggtggat gccgacgcac ttaatatcct
     1381 cgccaaccac cgtcatgcac ttacccacct gccgaagggt tccatcctca ccccgcatcc
     1441 gaaagaactg gaacgtctga ccggcaaatg ccaggactct tacgaacgtc tgatgaaggc
     1501 ttgcgaattg gctcgtgccg cccatgttca cattatttta aaaggagcct actccgccat
     1561 tatcacccca gaaggtaaat gtttcttcaa cccaaccgga aatccgggaa tggcaaccgg
     1621 aggtagcggt gacgtactga ccggagtaat cctggcactg cttgcccaag gttactcaac
     1681 cgaagaagcc gctaaaatcg gcacttacat tcacggattg gcgggcgatg tcgctcaaaa
     1741 gaagcaagga atgatcggaa tgatcgcaag cgatattatc acctgtctgc cgacagcatg
     1801 gcaacttgta agcgaataaa agttaagaac ttaccctttt ttcaataact tcattaactt
     1861 tgttttcaaa accagttaaa aaagaaccga atatgaaaaa gttgattata gcagcaggac
     1921 tactaatgac aacgtccgcc tatgcacaaa ccgaagtact gacaggggtt acccgaggaa
     1981 aagactatgg agtggtttac agtcttccca aaacccaaat agaacttgaa ataaaagcca
     2041 acaaagtcaa ctatactccg ggagaattca gcaaatatgc tgatcgttac ctgcgactga
     2101 ccaacgtctc cgccgatcct gaagagtact gggaactggc tagcgtaaaa gtgaaatccg
     2161 taggtgtgcc caacagcgaa actacgtatt tcgtaaaatt gaaggataag acagtagcac
     2221 cgctcatgga actgacagag gatggcattg tgaaaacgat caatgttcct tacagcaaca
     2281 gcagtgtaag caaaaaagtt gctcccgctc ccgcagtcct ccaaaagaaa gcgaatcctc
     2341 gcgaattcct gaccgaagag attctgatgg ctagttctac cgccaagatg gccgagctgg
     2401 tggctaaaga gatctataac atccgcgaaa gcaaaaatgc cttattgcgc ggacaagctg
     2461 ataatatgcc ttcagatggg gcacagctta aaattatgct cgacaatctg aatgcacagg
     2521 aagaagccat gacacaaatg ttctccggca cctgcaacaa agaagagaga acattcactg
     2581 tccgccttac ccctgacaag gaattcaaca atgaagttgc tttccgcttc tcgaagaagt
     2641 taggtgtagt tgccaacaat gatttggcag gaactccgtt ttatatcagt ctgaaagacc
     2701 tgaaatcggt caagatgcca caggaagatg gtaagaagaa gaaagatttg gatggaatcg
     2761 cctacaacgt acccggacaa gctatggtta cactgaccga cggtaaaaag aaactttacg
     2821 aaggtgagct tcctattacc caattcggtg tgatagaata tctggctccg gttttgttca
     2881 acaagaattc taccatcaaa gtttattttg atccgaatac gggaggattg ctcaaagtgg
     2941 acagagaaga agggaaatag aaaaacgagg aagtaaactt ctaaaaaaaa agaatatggt
     3001 tggtgaagga catgcattcg acatgatacg ccgaataaaa gagggacggg aagcttcccg
     3061 cctacgtcgt gaacgtgcta acgataagtt gaagcatcta aaccgtgcaa acgaacctta
     3121 tccactaccc aacaccaccc ccgaagaaat ggaacgtatc atccacgact cggagaaaaa
     3181 gaaagagaaa gacagcaatt attttgtttg gggaacgctt attatcatgg gggtcctgat
     3241 agcaattgcc gtcatacttt gggctgtatt tatcaaataa ataataataa gttcctattt
     3301 atacgactgg tatcaccagt tttataaatc catctttctg catttgagaa agataagccg
     3361 atacacgcga ctcgtagccc tcttcatttt gaaagtggtc tgcgagtttt tctataatct
     3421 cacgaacatt gcgttttcca tctatcagtt cccatacagc cgtaccgtgt tcttccaatt
     3481 tcacatgaag ttctttcgac attcctttcg gcacaaggaa gcgttgcatc cacggatatt
     3541 taaaacgggg aaaggagagc acaattgtct ccccttccct ttctgctgta atatgttcac
     3601 tgcgacaggg aatgacctct aacaggttga ttttctcttt ggcagccata cttcttattt
     3661 tttatttcag agtattcata ctgatactct tctgtttaca ccttgataca aaattccttt
     3721 gtcactttag gtattgaatt tcctagttac ttttggatat tcgcctcttc caaaccgtat
     3781 cccttcttct tgttctctgc cttcaacatc aaagccacaa tcagagcaag cacaccaaaa
     3841 agagcaaaaa tagtcatcgg caacgtgtag tcataagtct gtgcaccgtc tactaccgga
     3901 cctttgcaat aagtattcaa cacccatccg atcaacaaag gaacacccat caatccccag
     3961 ttctgtaccc agaaaatcaa tgcgtatgct gtacccaact gtttttccgg aataatcttc
     4021 ggaacagacg gccacatagc tgaaggcacc aacgagaagg caaaccccaa tataatcatg
     4081 atgatagtag caaaccacca tatattcagt ataggcagag caaacatcgt atgcacaaaa
     4141 ataagcatca ctgatccgat tatcatcaat gtggctccct taccaatacg gtcataaagc
     4201 gagccgaaca acggagtcag aataatcgca ccaatcggca acaatccggg aatcgttccc
     4261 gccaacttcg gatctacatt atacttctgc accatcaagt cggcagcata cttgataaag
     4321 gggaatacag ccgagtagaa caatacacat agtaatgcaa tcagccagaa tcctttattg
     4381 gtaatgatat acacaatatc tttcatacgg aacggctctt ccggttccaa tccctctgca
     4441 tccaaagaag catccaactt cttatcatag aaagtataaa gaaagaaagc aatcgtaccc
     4501 acgcacaaca taatcagaca aaacaaaatc ggagtaggaa tattggtatg gaatgtgcca
     4561 ctctcatccg tagatccgaa aaagtcggcc aaaggaaccg taagcaccat tgccagagtt
     4621 gttccgatac gtgccgtagc catttcaagt cccatagcca acgccatttc cttacccttg
     4681 aaccatttca cgataatctt ggaaactgtg ataccggcaa tttccacacc tacaccgaag
     4741 atagcatacc ccaatgcagc cagggttacc tgtgttttga atccgaagag catggcacct
     4801 tccggaaaag tagtagaaat cgcatagtat ttcaatccac aaccaaacac catcaataag
     4861 caagctccca ttccggtgaa acgaaccccc atcttatcca aaatgatacc accgaagatc
     4921 agcatcaaca ggaatacatt aaaccatccg taagcgcttg tgaagaaacc ataatcaaga
     4981 ctgtcccata gtagttcttt ctcaagcatg ggttttagag gagacattac gtcggtgagg
     5041 aaatagccgc atagcatagt aaatgcgact aatgctagaa cactccatcg gagtacggcg
     5101 gagtcattca atttctgttt caaatgttct gtcattgtta tatttaaaaa tagtagttaa
     5161 taatcttata cagccaacaa aggtagttaa atctcgtttg tttctatcac aaagagattg
     5221 tttttacaag aaaaagttaa gtgcggatta cactgaccac gcggaagatt gaaaatccgt
     5281 gtaatctgcg taatccgcac ttaaatatca aagaaatgca gcatccgtct gcaccttccc
     5341 attaatggtt ttaccccaaa gtcttacctg acaacggagt gaattactct gctgcaggag
     5401 caggagtttc agcagccggt gccggagttt ctgtagcagg tgcattggta gcaggagctt
     5461 cagtttgcgg cgcagccgta cctgcgggta agttatacgg gttagtctgt tgttctttct
     5521 gtgcctgttc caacactgcg tctttagcaa cagcagagcg aggaactaca taagcagtag
     5581 caatgctcat taccaccatg aagatagcta agccccatgt tgctttttcc agaaaatctg
     5641 tagtcttgcg cacgcccatg atggcgttag atgaagagaa accagaagca agtccgcctc
     5701 cttttgagtt ctgaatcagc acgatgaaac acatcaacaa ggctgcaata accattaaga
     5761 taacgaataa taagtacatt tttagttatt ttgaattagc gttaataatc aatttctcca
     5821 aaaatctgat ttggtctgca aagtaagcat ttttttttgg atatttcaag cttaattttt
     5881 taattatttc aagagctttt gaatatcgtt gctgtttaac atagattttt gccaaagttt
     5941 ccgtaaaaca gctgtcatct tcctcttctt ccttcatcgt ttcttcttcg gtaagttcgt
     6001 ccgaagaggt tggcgaagat ggcatttctt ctcttaaagg tttcttgcag aggggagagt
     6061 cgctctcgct cttttctata aagtcgtcaa tcagttcgta gcctttgagt ttgggcgttt
     6121 cttcggccga ctgttccgtg gccggagtct cctccaaaag ataagaggtg taatccatcg
     6181 aatagtcgaa gctggtgcgg gcagtcacct cttcgggtac tgtggacaag aaagcgtcga
     6241 tcaatgctaa tgtgcggtct acggacggtt cgtctttcaa cacctccgtg agaggtactc
     6301 cctttttccg tgcctgcaca tcatagcggt caccttcaat caaccggaac aactgccgtc
     6361 tgtctgcaat gtaaagaact gctttccgca gttctccacc gaaactaata tcatggagaa
     6421 tatacagatt cttcagatac agcagacgaa gtgactgaaa atacggatac ctcgcaagaa
     6481 gattgcgcag ttcgtacaaa gtatccctat tcagcgtctc gggatgctga atccattgtt
     6541 gaaagttaac agaagtcatt tatattacca gtttgctaca gttgcattaa aaatttggtc
     6601 ggtgatctct ttagacattt cagcaatcaa tccgtcctgt acggcagtca gcaactggct
     6661 agagtcgtag gtacggaacg cagaaaactg ttgttcaaag tcttcggcat gattggtgtt
     6721 gttgacaaaa cgtacattga cggtaatagt caacttcgtc tccgaagaat aaccgtcggc
     6781 agatactgcc tggttgtact gattgtaacc tgtgatttct ccgtcaatct gcaagtcggc
     6841 attctgattc ggcttgagca gttgcagacg ggtctgccgg atgaagatat ctttcaggtc
     6901 ctcattgaat ttggttgcca acggagcata tacatactcc gacttgatcg ggaagtcggc
     6961 tatcgaaatg gtctttacct tatcataatt gatagacgat ccgttaaact tataggaaac
     7021 agtgcacgca atgactacca acggcaagcc gaacagtaac aaagggcgta ttattttctt
     7081 aatccaattc atattctttt atttttctat aaagtgtacg ctcggaaata ttcaagtcct
     7141 tggccgcact cttccgcttt ccatgatgcc tctcaagtgc tttgcgtatc atttctttct
     7201 ccacttcgtc cagtgacaaa ggagattctt ctacatattc ttccgtgtct tgtatgtcat
     7261 catcatcctt gcaaaccgtg ggctgcatgg tgtgaatgat agcaggtacc gaaggttgat
     7321 gcgccgtcac taccggagta gtaaccaccg ttcccatttg tcctacctgc cccacctgtc
     7381 cggcacgttc cgccatcagg ttgtgcacca tcttcttcag ctccgccact tcctggcgca
     7441 tatcgaacag aacagaataa agaatctccc gttcgctctc aaagccttta ctctcacgcg
     7501 ttcccatcag cgcgggaaga cgttgcgtat tttgtgcggg aagataattc tgcaagatag
     7561 cagcagagat ctccctattg gtttcaatga tagatatttg ctcggtgatg ttcttcaact
     7621 gacgcacgtt tccgggccac gggtaagcta acaactcttt cttcgcatcc tccgtcaact
     7681 gaatagcagg catccgatat ttctctgcaa agtctgcgga aaacttacgg aacaacaaaa
     7741 gtacatcgtc accacgttca cgcaaaggcg gtatttggat aggcaccgta ttcaaccggt
     7801 aatataaatc ttcacggaaa cgtccttctg caatcgcttg tgtcagattg acgttggtag
     7861 ccgccaccac acgcacatcc gttttttgta ctttggacga acctactttc ataaactcgc
     7921 cactctccag tacacggagc aaacgtgcct gggtagacat cggcaactcc cctacttcat
     7981 caagaaaaat agtaccaccg tcagcttcgc caaagtaccc tttccgttcg ccaatcgcac
     8041 cggtaaacgc acctttctca tgtccgaaca gttcggaatc aatcgtacct tccggaatag
     8101 cgccacagtt gacagcaata tactgtccgt gcttcctccg gctatattga tgaataatct
     8161 gcggaaaact ttcttttccg actccacttt ctccggtaat cagcacagac aaatcggtag
     8221 gagctacctg aatggcaaca tctatggcgc gcgacaatgc ttcagtattt ccaataatac
     8281 cgaaacgctg tttcacttgt tgtatctctg ctctcgtcat cactcgtttt taatcttcgt
     8341 ctactgtatc cagcttcagt ttatcactat cgtcacgttt ctcgtaatac tgtttacgca
     8401 acggattggc acgagccact ttttcccgct gacgattacg gaacacgtcg atggcaacat
     8461 agattgcctg gcggaaagaa tcttcacaag ccactccctt acctgcaata tcgtatgccg
     8521 ttccatgagc cggagaagta cgtactaccg gcagtcctgc cgtatagttc accccgtctt
     8581 ccatagccaa ggccttaaac ggagccagcc cttgatcgtg atacatcgcc aggataccgt
     8641 caaaatgagt ataattgcct gaacccataa agccgtcggc cgcataagga ccgtagcaaa
     8701 ggattccttt ctcttccatt tctttcatgg cagggataat cacttcctgc tcttccattc
     8761 ccaacaaacc accgtctccg gcatgaggat tgagagaaag caccgcaata cgcggagcgc
     8821 cgataccaaa atcctgtttc agacaacgat ggaatatcat cagtttctcc tgaatcaatt
     8881 ctttggtaat cgtagtcgcg atctctctga cagggatatg tgtcgtcacc aaagccaccc
     8941 ggaagtcatt cttcatcaaa atcatcaatg acttatcacc attacccaga cgttcttcga
     9001 tatattccgt atgtccgggg aaggagaact cttccgactg aatcgtatgt ttgttgatcg
     9061 gagctgttac gataacgtct atcaaccctt cgcgatattc ttcgatggca cgttccaaag
     9121 cccccaacgc agctttaccg gcttcgggat cgggtttgga aaattccact ttcacctcat
     9181 catccgtaca gttcaccacg ctcaaacggt tgtaccccgc ctcggtagca gagttgacaa
     9241 tgctaaaatt ggcctgtata tccagcgctt tgcgatgata agccgctact ttcggtgagc
     9301 cataaatgat cggagtacat agttccaaca tcgtagggtc ggaaaatgtc ttaagaatca
     9361 cctcatagcc caccccgtta atatctcctt gggtgatacc tatccttatc ttgttatctt
     9421 ccatgttttt atttattagt ttgttccgct tccttagatg cttctcccaa tggaatctgc
     9481 ttctgctgaa cttcattcgg aagtttcagt gtatacagag atgcttccat ctggcgtacc
     9541 aggttgcgtt tcattttatc aggtgaataa acaaatattt ctgctgtaat aattcgttgg
     9601 tttttctcgt ccaaacgagt gtgagagaca tacggaccac ccataaagtc gcccttcata
     9661 cgccacaggc cacgtgcttc cattgtgtag ctgttctgca cattgatcgg acggacatcg
     9721 gtcagcaaac tatcggtcga catataaacg ccttccttga atccggggat attggctttc
     9781 atcacagagt cacgtttgtg cacaaaatat tctttggtaa acgtatcctt gtcagtgtac
     9841 ggataagagt acatcacaaa gttacggtcg gcagtacctg tgttggtaga agcccagaag
     9901 aaatcatccc cggtctttga attagccagt tcggcatcca cccagatgtc gcatccgaac
     9961 aaactgtcca ctttctgcga aatgaagtta ctgtgtttcc cttccaggaa cgtaatctga
    10021 cggttcattt ccgcacgggt aaagaagtcg acaatcgtct ttttgttctc ttccacaaac
    10081 ttctcgaact cttcttcgtt cggagcctgg atagtcaata tcatctgcgg attggcatac
    10141 acgtccttcg catatttgaa cgaggctttc gtatatatat cctgtatatc tacaataata
    10201 atgttacgta tcaacttcag cgtagaatca taatctttcg gtgaagtata cataatccgg
    10261 aaagaaggtt ccgactgcgg caaaccgggc atatcagcat cgagcgcatc atgtaaagcc
    10321 cttccggcag cacgatccca aacaccgtga tctactacaa ccaaaagctc gtaagcacga
    10381 ccactagagg tgtgatttcc tttcagacca caagatgcaa cgacaaaggc taccaaagcg
    10441 atgcataaaa taaaagagta ctttttcatg atgttcggtt ttatatatta actttcatta
    10501 tttttctcct gtttcgctgt cgacagcata ccgcaagcgg caaaaatatc ttcgcctctg
    10561 gatgaacgga tagtggtgaa aagtccgtgt gacgtcagat aatcacgaaa acgggtcatc
    10621 gtatccatgt ccgccccctc aaggtctacc cccggtatgg catgaaaacg aatcagattc
    10681 accctgcaat ccagcccgcg aagaagtttc agcaactctt tggcatagac ctgcgaatca
    10741 ttgagccctt taaaaacaat atattcaaac gaaagtcgac gttgtttact aaaatcatag
    10801 ttttttaaca gttccaccat ttcggtgatt gaaaacgcct tttccgccgg cattaattca
    10861 gcacgctgaa cggtcagcgg agagtgaagg ctgatggcaa ggtggcagtc attttcttcg
    10921 ataaaacgct gcaatccttt ccgtagcccg acagtagaaa gcgtgatacg cttcggactc
    10981 catgcgtaac cgtaggtagc ggtcagtagt tccaatgcct tcaatacctc atccaggtta
    11041 tcgagcggct cgcccattcc catcattacg acattagtca gtttgtcccg ttccggcagc
    11101 gaatgaatct ggttcatgat ctggctggcg gtcaggttag ccgtataccc ctgtttgccg
    11161 gtcatacaga acttacagtt cattttgcaa cctacttgtg acgacacgca caacgttgcc
    11221 cggtcatcat ccggtatata aaccgactct acaaaatggt tctcacccac tttataaaga
    11281 tacttcaccg taccatctac agagcgcatt tcatctaccg gagcttccgc tcccacctca
    11341 tagttctgct tgagcaactc ccggtgtttc aatgacaaat tagtcatatc atcaatcgag
    11401 gctaccttct tttcgtaaag ccaggatgca atctgcttgg cagcaaagcc gggcataccc
    11461 agtctttttg tcaatgattg aagctctaca agagtcattc ctaaaagggg atatttagac
    11521 attcttcttt ctgttgatag tttatatctg caaatgtaag gaaataaagt cgatttccgt
    11581 atagcaggaa tgtaaaagtt aacaaaaaag ggaagtatac ccaagttatt atttaacaaa
    11641 gctgatatat tgaagtagcg ttcgcgccaa ttcagagtcc tcgccattcc gtttcacttc
    11701 gtgaccatac gcctcacgga aacaagccag cgcatctttc cgttcataac aatatttgtg
    11761 taaaacccct aagttttgac aagccacaat cgtatcttca ttctcccatc cctgatgctt
    11821 ctttcgcagt tcaaactctt tgaagaaagc cgctttcgcc attggataat ccttcttttt
    11881 cgtataagcc agtgctttgt agtaatatac cagacaggaa gaatcggggt caccatcatc
    11941 atgaatatcc agggaggttg ctatacgaat cacattatca taatctttat tcatgtaata
    12001 ttgctgcata atatcacatc ttaatgcctc gtaacggata gtcaattctg ccaaacgagg
    12061 cttttcgctg aaaaacactt catgcagaag agactcatgg aagaataaag tagcggcctg
    12121 ctcatcgtta cgctcattca ttatgcgttt gaattctatg catagataat acaactgttt
    12181 atgacaagcg actatctgct ttctattatc tatctgcata gaaatatcca atgcccgatt
    12241 catcagattc cacgcttcat cgtattgctt aacacaataa agacatctac cttgcatacg
    12301 catgcattta gccactccac ttgacaatct accattcaaa gattcgtgca ttttagctac
    12361 tttccggaat tgttcggccg cactctcttc gtttttctta taataatcgc aataagccag
    12421 cagttcgtaa agttcaatga tttctgccat attattctcg tcagtagaag ccgcatgata
    12481 gccaagcgct ctatttagat aagtcaccgc ttcattatat tgcccattat aataacatgc
    12541 catccccaaa ttcctacatg tatcagtaat ctggggtacc ggaatcggta ctatattttc
    12601 ctgcatcatc aatgctttca ggaaacaatc acatgccatt tcatattctt cgtcacgggc
    12661 atagcgacat ccctcgttca ttttcagcac tgatctggca attggcggta tggcagctcc
    12721 ttccatacat ttctcactca caacatttgc tacctttgtc aggtgaaaag aacgacttaa
    12781 gaaagtagct atatcattag caatgacagg aatcaaaaaa gaatcaacct gaccaaagtc
    12841 cgattcggca tagacatcag gcataaaaga agagtcgtcg ctcataagtg ccttccagca
    12901 atcttccaac aaagaataat tcgtacgata cagaatttcg aagagttcta catcacaaat
    12961 ccactttctc aagaaattcc gctcctgcat cttataacct tgataagtaa tttccacttt
    13021 atagcgataa gaatcatggt agcagaactg tttcatacga tagctataat cagcaaaagt
    13081 cagttggtgc gaaaggatat cttcattgtc cagaaaagag gttattattt tatgacgaca
    13141 cttatcgatg cacatatcgc cttgagcgaa gcatcgttta atcgcctcta ccatttgtgt
    13201 gtcacaaata caatatcgcc ctcctttgtt ggtgagccag ctactcattt ccactttcaa
    13261 ctgtgaccaa agcatctgat ttatgcctgc catgctcttt acttcatctt cggtaaatcc
    13321 ttctaaagta agtgaaagca tcagaagcgt tcttccaatc tcttcgaaac cataatcagc
    13381 cgacaaacgc cgaagcacac tgtcataaaa ttgctcaacc tcattgagcc ggcaatatcc
    13441 actcatatat tcatagagag catcgtactg accgaacgaa accagctcat tgagcaatac
    13501 acttaaacag cgcggttgtt tagccagcac ccacgaacca agaatatctt cctgctgtgc
    13561 agacaaggtc ttggagtaag cagacaaata ttgttttgag aactccttag catccacttg
    13621 tgaaaaacca ttcaactgga aatgaacgt
//
