LOCUS       gnlProkkaPAPBBLMM_36   11794 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PAPBBLMM_36.
ACCESSION   gnlProkkaPAPBBLMM_36
VERSION     gnlProkkaPAPBBLMM_36
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 01:28:20
            Original ID  :: gnl|Prokka|PAPBBLMM_36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11794
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1254
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 71.4;
                     E-value: 9.2e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="MRFTNKLEIRGAVYRPGIYQLSGKLNTIRELVHEAQGLTGDAFLN
                     RAVLYRQREDLTSEVVQIDIKSIMNGTSPNLALMKNDILYIPSIHDLEDRGNVTVHGEV
                     AHPDSYPYADNMTLEDLIIQAGGLKEAASTVRIDVSRRIKNPRSTADNDTIGQMYTFSL
                     KDGFVIDGQPGFILQPYDEVYVRRSPGYQAQQNVVIDGEILFGGNYAMTNREERLSDLV
                     NKAGGPTSLAYLRGAKLTRVASAGEKKRMGDVIRLMSRQLGEAMIDSLGIGVEDTFTVG
                     IDLEKALTNPKGSADLVLREGDVVFIPKNTNTVTINGAVMVPNTVSYMKGKDVDYYLNQ
                     AGGYSDNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVPGKAKKKGNIANILGYAT
                     SFSSLGMMIASIANLIKK"
     protocluster    1..11794
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2480:6794]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2481..6794
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11794
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11794
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             1269..2417
                     /locus_tag="ctg36_2"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             2481..3200
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.3e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.8e-17, bitscore:
                     52.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             3221..4522
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209;
                     E-value: 1.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_4"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.7e-122, bitscore:
                     395.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-63, bitscore:
                     204.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             4539..5663
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5673..6794
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.8e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg36_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_6"
                     /sec_met_domain="Aminotran_5 (E-value: 1.7e-31, bitscore:
                     99.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     VCALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5763..6770
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg36_6_Aminotran_5.1"
                     /evalue="2.80E-34"
                     /label="ctg36_6_Aminotran_5.1"
                     /locus_tag="ctg36_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRVCALGEIEVDDIENFFKVLKAALNHY"
     CDS             6791..7264
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 73.7;
                     E-value: 2.7e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYSNIY
                     LGKNAEIRSGCYLIARDKIIIGENSTLAYGTTILTTADPNGPYNALAVLYPYKKAPVVI
                     GDNVWIGANVTILPGVTIGDYVVVAAGAVVTKDVPSGVLVAGVPAIVKKRFNK"
     CDS             7261..8706
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_8"
                     /sec_met_domain="Polysacc_synt (E-value: 9.6e-33, bitscore:
                     103.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKTSLKNKAICGIFWSAVERFLSQGIQFVVTVIMARFLLPSDY
                     GMVGMLAIVLQLSQTLMDSGFTNALIRYKERTEIDYSTVFFFNILASLVIYFLIFFLAP
                     YISWFYKIGQLVEITRILSIVIVLNSFAIIPKTKLIIAVDFKTQSKVSFIAALVSGIIG
                     IWAAYLDFGVWALVGQTLVNGLLIVVLYAYFCRWKPLWIFSLKSFRLLFAFGSKLVLAN
                     ILNTLYKNLYAIVIGKKFSSVDLGFYTRAEQFAQFPSYNLSAIISRVTYPILSLVQNDN
                     DRLSALYRKYVRLSSAFIFPLMILLIVIAQPLVLLLLTEKWIGVVVLLQILCLDWMFDH
                     LSSINLNLLYVKGRSDLALRLEVIKKVLATGILLLSIPWGIVGMCWGRVMYSLIAVYLN
                     TYYTESLIKLSLIRQMRDILPSFFLALIMGGGTWYMILLLEGEIVQIVVGSVIALLLYG
                     TLLYCFSRSLFDEIWAVILKIKR"
     CDS             8706..9428
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MDKLSLIISKIRRNHWYRTYMRPIYLFVYGNRKLKNRNRIFLQYS
                     QELLTNFHQAMNEVGIPYWLEFGTLLGAVREHSFISHDFDLDVGLFKEDYSDIIREVLK
                     KYGFKRIRCITALDFIDAYEETYLYKGVTIDLFLFSREKNCDGVYCYDFVPVYSDIKRT
                     KKGDNAIRRIHFPRIDLIEYSFIGINTFVPENYEEHLCMHYGKDYMIPNPHWKDSDAQH
                     TDIFYGREIRIELFDKSK"
     CDS             9442..10455
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MFYLFFLLIVLFLLYIQSRKRQYSTVAGICVPIIIIFVVICRYRV
                     GYDYLTYYTLIENEEEAQILYLFSPLSIVWAEIALYFESPQMLFVLFGLPTFALLIFTL
                     KKYSKDYALSVTILICFFFFTSLSIIRQALALAICFYGYRFIVKRSLIKYILCILIAAL
                     FHPSAGVAIIIYWLPFLKFRLVVLLSIISIVAKPLFFYMLNILGVYTSYLDGKMDIEGG
                     KYTQLIYFLLFIICFVLGSKNIDKNKCNLFNVLLLSFVFVSFLGAHLGGRIAFYFNIYY
                     CLLIPKVVKGLDGQLREQVKLLSYFLCISYFLLYLFVPFIKGVPSYYIPYKFIFFK"
     CDS             10460..11419
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 57.2; E-value: 3.2e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_11"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-42,
                     bitscore: 135.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLISIIVPCYNSERYLSDCLLSILNQTYVNWEVICIDDGSQDNTL
                     SILNHYATLDERFKIISQSNAGVSVARNKALSQCQGEYICFVDSDDLIEPNFLITLLQL
                     ISHQADLAICGFTRSMVFCMDDAQGYIEMSGKRCIERIILDKSFNPQICCMLFRHNIIK
                     EKQLEFVIGCTRGEDREFILKYLVYSNKVCYTNNLLYHYRVNDQSAMAIFSIKSLTSIE
                     ASQRTVNYYKKVNYSVRGLEFEFSRTLWKFMILAILSGQNDLYQIIREKYDLKRQMEHL
                     YSHPGLSEKLTARLFVWNEALFKWVFSIIRYLYKKRWR"
ORIGIN
        1 aaccgcttca caaacaaact ggaaatccgt ggcgctgtct atcgtcccgg tatctaccag
       61 ctcagcggta aactgaatac gatccgcgaa cttgtccatg aagcccaggg cctgaccggt
      121 gacgctttcc tgaatcgtgc cgtcctttat cgccagcgtg aggatttgac cagtgaagtt
      181 gttcagatag atatcaagtc tatcatgaac ggtacttccc cgaaccttgc cctgatgaag
      241 aatgacattc tctacatccc gagcattcac gatctggaag atcgtggcaa tgtcacagtt
      301 cacggtgaag tcgcgcaccc cgattcctat ccctatgctg ataacatgac acttgaggat
      361 ctgatcatcc aggccggtgg cttgaaagaa gccgcctcta ctgtccgcat tgatgtgtcg
      421 agacgaatca agaatccccg tagtaccgcg gataatgata ctatcggtca gatgtatacc
      481 ttctctttaa aggatggttt tgtcatcgac ggtcagcccg gttttatcct tcagccttat
      541 gacgaagttt atgtccgtcg cagtcccggt tatcaggcgc aacagaatgt agtcattgat
      601 ggtgaaatat tgtttggagg aaattatgcc atgaccaacc gtgaggaacg tctttccgat
      661 ctggtgaata aagcgggtgg tcctaccagt cttgcctatc tccgtggtgc gaaattgacc
      721 cgtgtggcaa gtgccggtga gaagaaacgt atgggtgatg tgattcgcct gatgagcagg
      781 caattgggtg aagccatgat tgactctttg ggtattggtg ttgaggatac ctttacggta
      841 ggcattgatc tggagaaggc tttgactaat cctaagggta gtgccgacct tgtcttacgt
      901 gaaggtgatg tggtctttat acctaagaat actaatactg taactatcaa tggtgctgtc
      961 atggttccga atacggtttc ttatatgaag ggaaaggatg tggattatta cctgaatcag
     1021 gccggtggct attctgataa tgcaaggaag agtaagaagt tcattgttta catgaatggt
     1081 caggtgacga aggttaaggg tagtggtaag aaacagattg agccggggtg tgagattatt
     1141 gtgcctggta aggctaagaa gaaagggaac atagctaata ttttaggtta tgctacttcc
     1201 ttcagttctt tgggtatgat gattgcttct attgctaatc ttataaagaa ataatagaat
     1261 ttacttttat gtcagaacaa cgacaggata aaaacttgct ctctgaacca cacaagacag
     1321 aaagtgatga gatagaaatt gatttggtcg atatctttcg caagattatt gctattcgta
     1381 aaaaattata caaagccgtt ggaattggtt ttattattgg aataattgta gcggtaagta
     1441 tccctaaaca gtatacagta aaggttaccc tttctcctga aatgggtaat gcgaagggga
     1501 gtaatggttt agccggactt gctgcctcgt ttttaggaga tggggctcta ataggggaaa
     1561 gcacagatgc cttgaacgct tctctttcag cagatattgt ttcttcaact ccttttttat
     1621 tggaactttt agaaatggaa gtctccgttt ctaaaaagga tgataaaatg actttggggt
     1681 cttatctcga tgaagagtca tctccttggt gggattatct tataggtttt ccgggcatag
     1741 taataggagg agttaaatca ttattcggag aagatacggt tcctgccagt ggagggcggc
     1801 aaggaactat cgaattgacg aaagaagtaa atgagaagat taattttctt aaaaagaaga
     1861 ttagtgcatc cattgataag aaaaccgcca taacgagcat tacggtcacc ttacaaaatc
     1921 cgcagatcac tgcggttata gcagattctg tcgttcataa attacaggaa tatattattg
     1981 ggtatcgaac ttcaaaagta aaagaagact gtgcgtattt ggaacggttg tttaaagaac
     2041 gtcagcagga atattatgct gctcaaagaa aatatgcgga ttatgtagac gcccatgata
     2101 atgtggttct tcaaagtgta cgtgctgagc aggagcgttt acagaacgac atgagtttgg
     2161 cttatcagat atatagtcag gttgctaatc agttgcaggt atccagagcc aaagtacagg
     2221 aggaaaagcc agtctttgca gtagttgagc ctgccgttgt acctttgaaa ccttcaggta
     2281 tgggactcaa aatttatatt ttattatttg tgttcctgtc cgtatctggt actctcgtgt
     2341 gggtgctttt tggcaaaagt ctgctggcta gcttgagaaa agaactgaaa aataaggaga
     2401 tagaacagga taaatgatgc taaaacgtcg tttacaacat tcttacatca attaaattca
     2461 cttactatat tattaaacga atgatacgta cagctatgat aatggctgcg ggcatgggaa
     2521 cccgttttgg ccaatataca gaattgatac ctaaagggtt cgtcaaagtg ggaggtattc
     2581 caatgatagt tcgttctatt gatactttgt tatcatgtgg cattgagcga attgtaatcg
     2641 gtacaggata taaacaagaa gtttatgaag aattgaagac agactatcct atgcttgaaa
     2701 cctgttttag tcctcgttat gctgaaacaa atagtatgta tactttatat aatacgcggg
     2761 agattctggg caatgatgat tttttattgt tagagtcaga tttgattttt gagaaacaag
     2821 caataatgag cttattggag tgtcctgcgg cagatgcaat gctaataact ccagtgacaa
     2881 agtttcaaga tcagtattat gtggaacatg atgataattt tcgcctttct tcatgttctg
     2941 tcaataagaa taaactaaac gctaaaggcg aattggtcgg catccataaa ctatccggtt
     3001 ccttttacaa aataatgtgt gctgattatg cgagtattgt tgatgaacaa cccaatttgg
     3061 gatatgagta tgaattacta cgaatatctt gttctcaatc tcctgtttat gtgcataaag
     3121 tagaagggct gaaatggtat gaaatcgatg acatatcaga tttggaatat gcagagaaat
     3181 atattgttcc gtattgttaa ttaaaataat atatcaaatt atgagtaaga cagtttatat
     3241 tgggatgact gcggatatta tgcatccagg acttatccgc attattaatg aggctactaa
     3301 atacggtgat gttataattg gtcttcttac agataaagct attgcggagc ataaacgcct
     3361 tccttatctg acctatgaac aacgaaaaga ggtagttcag aatattaaag gcgtatgtaa
     3421 agttgttcct caagaagaat ggagctatgt tgagaatctc aaacgcatta aacctgacta
     3481 tataattcat ggtgacgact ggaaaaccgg gcctttacgt gaagaacgtg tgcgcgtatt
     3541 tgaagtgatg aatgaacagg gaggaaaggt tatcgaaatt ccatatactt tgggaattaa
     3601 ttcatcttct ttggataaag atattaaggc tataggtaca acccctgatg tacgtttaaa
     3661 atcacttcgt cgtttgataa atgccaaacc cgtagttcgt attttggaag ctcatgatgg
     3721 actatgtggc ttgataattg aaaatcagga aatattaaaa ggggataaga gggaagtatt
     3781 tgacggaatg tggtctagta gccttacgga ttcaaccagt aaaggtaaac ctgatattga
     3841 ggcggttgat ttaactaccc gattgcaaga tttgaataat attctggagt gtactactaa
     3901 acctattatt tttgatggag atacaggtgg taaaattgaa catttcgtat ttacagtacg
     3961 cactttagaa cgtcatggaa tctcagctat aataattgaa gataaagttg gattaaaaaa
     4021 gaattcattg tttggtacgg atgttattca aactcaagat acaatcgaag gtttctgtaa
     4081 taagatcaaa gcaggaaagg catctcagat tactgatgat tttatgatta tcgctcgtat
     4141 tgagagcctt atagcgggaa agccggtaag tgatgcttta gagagagctt ttgcatatgt
     4201 ccaagcggga gcggacggta ttatgataca tagcaaaaat aagtcgggtg aagatataaa
     4261 agaattttgt ttggcgtttc gaaaacagta tgctcatgta cctatcgtgg ttgtgcctac
     4321 tacatatgat catatttatg agtctgaatt gtgtgattgg ggtgtgaata taattattta
     4381 tgctaatcat atgcttcgtg ccgcttatcc tgctatgatg aatgtcgcaa agacaatatt
     4441 agagaatgaa cgtgctttag aggtgcgcga actgtgtatg cccataaagg aaatattgga
     4501 actgattccg ggtactaaat aaaaagagga atatcattat gttaagcgta gaaaaagttt
     4561 atgaaacgtt tctgagtcat gacgttgatt tttttacagg agttccagac tcattactaa
     4621 aaaatatttg tgcctatatc acagaccata cttcacgtga gaaacatatc atagctgcta
     4681 atgaaggtgc ggctgtagga attgcttcag gttattatat ggcatcaggt aaggttcctg
     4741 tggtttatat gcaaaattcc ggcttgggta atactgttaa tcctctgctg tctcttgcag
     4801 atgaacaagt atacagtttt ccaatgcttt tgatgattgg ctggcgtggt gaaccgggaa
     4861 caaaagatga acctcagcat aaaaaacagg gtgaggtaac tttagatttg ttgaaagcaa
     4921 tgcggattcc ttatataatt cttgattcaa atgagaatga tgcatttatt cagctccatg
     4981 atatcataca atcagcaaaa actaagaata ttcctcatgc aataattatt cggaaagatg
     5041 tttttggcaa atataaactt caaaaagagt tcggatgtaa ttatccttta tctcgtgagg
     5101 atgctttgca aatagttgtg gattatctgc ctgaaaattc agtggtcgtt tctactactg
     5161 gcaagctttc tcgtgagtta tttgaatatc gagaaatgaa agagcaaggt catgaacatg
     5221 attttctcac ggtaggctct atgggacata gttcatcaat ctctttgggt attgctatag
     5281 caaagcaaga tagacctgtt tattgcttgg atggtgatgg agcatttatt atgcatttag
     5341 gggcaattag taacattggc gatttatctc ctaaaaacta ttatcatatt ttgtttaaca
     5401 atggtgctca cgagtctgta ggaggacagc ctactttagg atttagttta gatattccgg
     5461 ctattgtccg ggggagcgga tataagcata cttatactgt ttgtacaaaa gttgaaattg
     5521 aagaagcaat gaagcagctt ccaaagttat gtggtcctgt tttgttggaa ataaaggtta
     5581 aaatagattc tcgggagaat ttgggacgtc ccacgactac tcctatagag aataaggagc
     5641 attttatgga ttttttaaaa taaatatatt cgatgaaaat agaaagaaaa atattattaa
     5701 atcctgggcc tgccactact actgacagtg taaaaatggc acaagttgtt ccggatattt
     5761 gtcctcgcga gaaagaattc gcaggtatga tgaaacaact tcgggacgat ttggtcagag
     5821 ttgctcatgg gaatttggaa aaacataccg ctgtattatt ttgtggctca ggaaccatca
     5881 atattgatat atgtctaaat tctcttcttc ctgaagacaa aagggtgctt atagtgaata
     5941 atggggcata tagtacccgt gctgtagaag tgtgtcaata ttatggtttg cctcatatta
     6001 atttggaatt ttccgtttac gaacgtcctg atttatcggt ggtggaaaat gtgttgcaag
     6061 aaaatcctga tatagctatg gtttatacta ctcatcacga gacgggtaca ggaattctga
     6121 accctattcg cgagatgggc gctatagctc ataaatatca ggctaaattt gtcgtcgata
     6181 ctacttcttc tttgggcatg attccttttg atatagagaa agataatgtg gatttttgta
     6241 tggcatctgc tcaaaaagga cttcaagcga tgacaggtct ttcttttatt ataggcaatg
     6301 aggaacagat taagttttca aaaaaatatc ccaagcgttc ttactattgt aatctttatt
     6361 tgcagtatga gaattttgag agaacaggtg aaatgcattt tactccaccg gtacaaacta
     6421 tttacgccac tcgtcaggca ttaaatgaat attttgaagt gggcgaagaa gctaagtttg
     6481 cccgtcacaa aagagttttt gaggctattc attcaggtat aaatgaaatt ggtcttaaaa
     6541 gtgtaataaa gcgtgaatgg cagtcaggac tggttgtctc agttcaatac ccagaagatc
     6601 ccaactggga ttttgagaaa atacatgatt attgttatga gcgtggattt acgatttatc
     6661 caggtaagat atcaactgag gatactttta gagtctgtgc tttaggagag atagaagtag
     6721 atgatattga gaacttcttt aaagtactaa aagctgcatt aaatcattat aacgtcacat
     6781 taccgatgtc atgattgcag aaatattatt gaagattcgt catttttatt tttcccttcg
     6841 tggtatacac ttccatccgg aaagtgttat ttctggagtg cctattcgta gctttcgctt
     6901 agtaggcaaa tatagcaata tctacttagg taaaaatgct gaaatacgtt caggctgtta
     6961 tctgattgct cgtgataaaa tcattattgg agaaaactca acactcgcct atggaacgac
     7021 tatattgaca actgctgatc ctaatggacc gtataatgca ttagcagttc tttatcctta
     7081 taaaaaggca ccggtagtta taggagataa tgtttggatt ggggctaatg ttaccatcct
     7141 tcctggagta actattggtg attacgttgt agtagcagct ggagctgttg taacaaaaga
     7201 tgtaccttca ggagtattgg tagctggtgt accagctatt gtgaaaaaac gttttaataa
     7261 atgaaagaaa aaacttcttt aaagaacaaa gccatatgtg gaatcttttg gagtgcagtt
     7321 gaacgatttt tatcacaggg gatacagttt gtagttacag tcattatggc gcgttttcta
     7381 ttgccatctg attatggaat ggtaggaatg ttagcaatag ttcttcaatt atctcaaacg
     7441 ttaatggata gtggttttac taatgccctt attcgttata aggaacgtac tgaaattgat
     7501 tattcaacag ttttcttttt taatatatta gcatcattag ttatttattt tctaattttt
     7561 tttctagctc cttatatatc gtggttttat aaaataggtc aattagttga gattactaga
     7621 attttatcta ttgttattgt tttaaattcc tttgcgatta ttcctaaaac taaattaata
     7681 atagctgtag attttaaaac tcaatcaaaa gtctcattta ttgcagcttt ggtttcaggt
     7741 attattggca tttgggctgc atatttagat tttggagttt gggctttagt tggacaaact
     7801 ttagtaaacg gattgttgat tgtagttttg tatgcatatt tttgtagatg gaaaccattg
     7861 tggatatttt cattgaaatc gtttcgttta ttatttgctt ttgggtcaaa attagtatta
     7921 gctaatattc ttaatacttt atataaaaat ctgtatgcta tagttatagg aaagaagttt
     7981 tcgtcggttg atttaggatt ttatactcgt gcggaacaat ttgctcagtt tccttcatat
     8041 aatttgagtg caataatttc tagagtgaca taccccatat tgagccttgt gcaaaatgat
     8101 aatgatagat tatctgcttt atataggaaa tatgtccgtt tatcttctgc ttttatcttt
     8161 ccattgatga ttttgttaat tgtcatagct cagccactgg tattattgct tttgacagaa
     8221 aaatggatag gagtagttgt attgcttcaa atattgtgtt tagattggat gtttgatcat
     8281 ttgagtagta taaatttgaa tttactatat gtaaagggac gttcagactt ggctttacgt
     8341 ttagaagtta taaaaaaagt gttagcgacg gggatccttc ttctatctat tccttggggg
     8401 attgtaggta tgtgttgggg gcgtgttatg tattcattga ttgctgtgta tttgaatact
     8461 tattatacag aatcattgat taaattaagt cttattagac agatgagaga tatactacca
     8521 agcttttttt tagcattaat aatgggagga ggtacttggt atatgatttt attgttagag
     8581 ggtgaaattg ttcaaattgt agtaggaagt gttattgctt tattgctata tggaacgttg
     8641 ttgtattgct tttctcgatc cttgtttgat gaaatatggg cggttatatt aaaaataaaa
     8701 aggtaatgga taaactgagt ttgattatta gtaaaatacg acggaatcat tggtatagaa
     8761 cctatatgcg tcctatatat ttatttgttt atggcaatag aaaattgaag aatagaaata
     8821 gaatattttt gcagtattca caagagctgc taactaactt tcatcaagca atgaatgaag
     8881 tgggaattcc ttattggtta gaatttggaa ctcttttagg tgctgttaga gaacacagtt
     8941 ttataagtca tgattttgat cttgatgtgg gcctttttaa ggaagattat tcagatataa
     9001 taagagaggt cttaaaaaaa tatggtttca aaagaataag gtgtataacc gcccttgatt
     9061 ttattgatgc ttatgaggaa acttatcttt ataaaggtgt gacaattgat cttttccttt
     9121 tttcaagaga gaaaaattgt gatggggtct attgttatga ttttgttcca gtatattcag
     9181 atataaagag aactaaaaaa ggtgataatg caatccggag aattcatttt cctagaattg
     9241 atttgattga atattcattt attggaatta atacttttgt tcctgaaaat tatgaggaac
     9301 atctttgtat gcattatggt aaagactata tgattccaaa tcctcattgg aaagattcag
     9361 atgcgcaaca tactgatatc ttttatggta gagagattag aattgaattg tttgataaaa
     9421 gtaaataata gtagataata catgttctat ctattttttt tactaattgt gctatttttg
     9481 ttatatatac aaagtaggaa aagacaatat tctactgtag cgggaatttg tgttcctatt
     9541 attataattt ttgttgtaat ttgtcgttat agagtggggt atgactattt aacgtattat
     9601 acattaattg aaaatgaaga agaggcacag attttatact tattttctcc tttaagcatt
     9661 gtttgggcag agattgcttt atattttgaa tctccacaga tgttatttgt tctttttggg
     9721 cttccaacat ttgctcttct aatatttact ttaaaaaaat attcaaaaga ttatgcgtta
     9781 tcagtaacta ttttaatttg tttcttcttt tttacatcac tcagtattat tcgacaagct
     9841 ttggctttgg ctatttgttt ttatggttat cgttttatag taaaacgttc actaattaaa
     9901 tatatattat gtatattgat tgcagcttta ttccatcctt ctgcaggagt agcgattatt
     9961 atatattggt tgccatttct aaagtttaga ttagttgtat tattatctat aatatcaata
    10021 gtagccaaac ctttattttt ttatatgcta aatatattag gggtgtatac ctcttatctt
    10081 gatggcaaga tggatattga aggtgggaaa tatactcaat taatatactt tttgttgttt
    10141 attatttgtt ttgttttggg aagtaaaaac atagataaaa acaagtgtaa tttatttaat
    10201 gttttattgt taagttttgt tttcgtatct tttttaggag ctcatttagg cgggagaata
    10261 gcgttttatt ttaatatata ttattgtttg ttgattccta aagtggttaa aggattggat
    10321 gggcaactaa gagagcaagt gaagcttctt tcttattttc tatgtatttc ttatttctta
    10381 ttgtacctat tcgttccatt cataaaaggt gtaccctcat attatatccc atataagttt
    10441 atatttttca aatagtaaaa tgttgatatc tataattgtc ccttgttata attctgaaag
    10501 atatttgtct gattgtttat tgtctatatt gaatcaaacc tatgttaatt gggaggtgat
    10561 ttgtatagat gatggaagtc aagataatac attatctatt ttaaatcatt acgctacatt
    10621 ggatgagcgt tttaaaatta tttctcagtc taatgcagga gtgtctgtcg caagaaataa
    10681 ggctctatcc cagtgtcaag gagagtatat ttgctttgtt gatagtgatg acctgataga
    10741 acctaatttt ttgataacac ttttacagct tataagtcat caggctgatt tggcaatctg
    10801 tggttttact cgttctatgg ttttctgtat ggatgatgct caaggatata tagaaatgag
    10861 tggtaaacgt tgtatagaaa gaattattct agataaaagt ttcaatcctc agatttgttg
    10921 tatgttattt cgacataata ttataaaaga gaaacaatta gaatttgtga tagggtgtac
    10981 tcgtggtgaa gatcgtgaat ttatattgaa atatttagtt tattctaata aggtttgtta
    11041 tacaaacaat cttctttatc actatcgtgt aaatgatcag tcagccatgg caatcttttc
    11101 tattaaaagt ttgacaagta tagaagcttc acaacgcacg gtcaactact ataaaaaagt
    11161 gaattattct gttagagggc ttgaatttga attttcacgt acattgtgga aattcatgat
    11221 tttagctatt ttgtctgggc aaaatgattt atatcaaatc attcgagaaa agtatgatct
    11281 aaaaagacaa atggaacatc tttattctca tccaggacta tccgaaaaac ttacagcgag
    11341 attgtttgtt tggaatgagg cactttttaa atgggtattt tctattatta gatatctata
    11401 taaaaaaaga tggagatgaa taaacgaaat agattatctg aacaagaaat aaaaaaagta
    11461 gaacttgacg ctttattgta tattcggaaa atttgtcagc aatatcatct tcgctattat
    11521 ttagcttggg gtactttgtt gggagccgtt aggcataaag gatttattcc ttgggatgat
    11581 gatattgata taatgatgcc acgttcagat tatgagcgat tattggagtt agttccttcc
    11641 ttgagacata gttattataa aatcttaagt aatccaaaga atgaggatta ttattatact
    11701 catgcaaaaa tgatagatac tcgtactttg tgtgtggaaa atgatttgca aactattcaa
    11761 aatatgggga tttgggttga tattttcccc ttag
//
