LOCUS gnlProkkaKHICBJJI_61 13649 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|KHICBJJI_61. ACCESSION gnlProkkaKHICBJJI_61 VERSION gnlProkkaKHICBJJI_61 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2024-11-17 06:11:45 Original ID :: gnl|Prokka|KHICBJJI_61 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 13649 ##antiSMASH-Data-END## FEATURES Location/Qualifiers CDS complement(1..126) /locus_tag="ctg61_1" /transl_table=11 /translation="MQHHYELTFISPEKDFWFFVKFGGNLFFISTVSLFFFLNPIK" protocluster 1..13649 /aStool="rule-based-clusters" /category="RiPP" /contig_edge="True" /core_location="[3298:3649]" /cutoff="10000" /detection_rule="minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])" /neighbourhood="10000" /product="RRE-containing" /protocluster_number="1" /tool="antismash" proto_core 3299..3649 /aStool="rule-based-clusters" /tool="antismash" /cutoff="10000" /detection_rule="minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])" /neighbourhood="10000" /product="RRE-containing" /protocluster_number="1" cand_cluster 1..13649 /candidate_cluster_number="1" /contig_edge="True" /detection_rules="minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])" /kind="single" /product="RRE-containing" /protoclusters="1" /tool="antismash" region 1..13649 /candidate_cluster_numbers="1" /contig_edge="True" /product="RRE-containing" /region_number="1" /rules="minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])" /tool="antismash" CDS 308..1819 /locus_tag="ctg61_2" /transl_table=11 /translation="MKIFPSSSIKKLDAYTIENEPITSIDLMERAATVLTKAITDRWNT ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYST EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWQLVSE" CDS 1893..2960 /locus_tag="ctg61_3" /transl_table=11 /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK DKTVAPLMELTEDGIVKTINVPYSNSSVSKKVAPAPAVLQKKANPREFLTEEILMASST AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD PNTGGLLKVDREEGK" CDS 2996..3280 /locus_tag="ctg61_4" /transl_table=11 /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK" CDS complement(3299..3649) /gene_functions="biosynthetic (rule-based-clusters) RRE-containing: PqqD_RRE" /gene_functions="biosynthetic-additional (rule-based-clusters) PF05402" /gene_kind="biosynthetic" /locus_tag="ctg61_5" /sec_met_domain="PqqD_RRE (E-value: 6.9e-11, bitscore: 34.4, seeds: 9, tool: rule-based-clusters)" /sec_met_domain="PF05402 (E-value: 2.5e-17, bitscore: 55.6, seeds: 461, tool: rule-based-clusters)" /transl_table=11 /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ KDGFIKLVIPVV" CDS complement(3747..5135) /gene_functions="transport (smcogs) SMCOG1106:major facilitator transporter (Score: 91; E-value: 1e-27)" /gene_kind="transport" /locus_tag="ctg61_6" /transl_table=11 /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPTPILFCLIMLCVGTIAFFLYTF YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA NIQK" CDS complement(5384..5779) /locus_tag="ctg61_7" /transl_table=11 /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP QTEAPATNAPATETPAPAAETPAPAAE" CDS complement(5786..6559) /locus_tag="ctg61_8" /transl_table=11 /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK" CDS complement(6565..7092) /locus_tag="ctg61_9" /transl_table=11 /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI TDQIFNATVANW" CDS complement(7079..8320) /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54 dependent trancsriptional regulator (Score: 390.2; E-value: 2.3e-118)" /gene_kind="regulatory" /locus_tag="ctg61_10" /transl_table=11 /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS ERTLYRKIKEYELD" CDS complement(8330..9424) /locus_tag="ctg61_11" /transl_table=11 /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN PLRKQYYEKRDDSDKLKLDTVDED" CDS complement(9429..10469) /locus_tag="ctg61_12" /transl_table=11 /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE AEQTNK" CDS complement(10488..11498) /gene_functions="biosynthetic-additional (rule-based-clusters) PF04055" /gene_kind="biosynthetic-additional" /locus_tag="ctg61_13" /sec_met_domain="PF04055 (E-value: 8.8e-18, bitscore: 57.8, seeds: 518, tool: rule-based-clusters)" /transl_table=11 /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC KMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES" ORIGIN 1 ttttatagga ttaagaaaga agaagaggga aaccgtcgaa ataaaaaaga gattaccacc 61 aaatttgacg aagaaccaga aatctttttc aggagaaata aaagtaagtt cataatggtg 121 ctgcattgaa ttattttttg gcggagttat tctaacactt aatagttcaa aaacagatat 181 ttctctgacc aaaagataga actaatgatg aattaaaagt tgcaattatg gttttcttcc 241 cacaacaaac gggaaaagtc agaagaatca tgtacatttg taatccgaaa actaaaagaa 301 catcgcaatg aaaatatttc caagcagcag tatcaagaaa ttggacgctt ataccattga 361 gaacgaacct attacatcaa tcgatctgat ggaacgtgca gcaaccgtat taacaaaagc 421 catcacagac agatggaata cggaaacgcc ggtcactatc tttgccggac cggggaataa 481 tggcggagac gctctcgccg tagcccgcat gatggctgaa aaaggatata aaatcgaggt 541 atttctcttc aacacgaaag gagaactttc acccgactgc caaaccaata aagaactggt 601 agaaatgatg gaagaagtaa aattccacga aatcagtacc caattcgtac ctcccgtcct 661 gacgcccgac catctggtaa tcgacggatt attcggttca ggcctgaaca aaccgttaag 721 cggcggattc gctgccgtag tgaaatacat caattcctcc cctgctatgg tagtagccat 781 cgacattcct tccggactga tgggagaaga aaacacattc aacgtaaaag ctaatattat 841 ccgtgccgac gtaactttca gtctgcaact gccgaagctc gcctttcttt tcgcagagaa 901 cacggaattt gtcggagaat gggaagtgct ggacatccaa ttaagcgaag acggtattga 961 agagatggaa acgaactacg aaatgttgga aatagagcaa atccgttcac tcatcaagcc 1021 acgcaaacag tttgcccaca aggggaactt cggccatgca ctattgattg ccggttcaaa 1081 aggaatggca ggagcctctg ttctcgctgc ccgcgcctgc ctccgttcgg gagtagggtt 1141 gctgactgtc catgcgccaa tgtgcaacaa cgacatcttg caaacctcca tacccgaagc 1201 aatcgtagaa accgacatca acgaaacctg ttttgccgta cctaccgaca cggacgacta 1261 tcaagcagtc ggcatcggcc cagggctggg acgaaacgag gaaacggaag ctgctttatt 1321 ggagcaactg gaacattgcc agactcctgt tgtggtggat gccgacgcac ttaatatcct 1381 cgccaaccac cgtcatgcac ttacccacct gccgaagggt tccatcctca ccccgcatcc 1441 gaaagaactg gaacgtctga ccggcaaatg ccaggactct tacgaacgtc tgatgaaggc 1501 ttgcgaattg gctcgtgccg cccatgttca cattatttta aaaggagcct actccgccat 1561 tatcacccca gaaggtaaat gtttcttcaa cccaaccgga aatccgggaa tggcaaccgg 1621 aggtagcggt gacgtactga ccggagtaat cctggcactg cttgcccaag gttactcaac 1681 cgaagaagcc gctaaaatcg gcacttacat tcacggattg gcgggcgatg tcgctcaaaa 1741 gaagcaagga atgatcggaa tgatcgcaag cgatattatc acctgtctgc cgacagcatg 1801 gcaacttgta agcgaataaa agttaagaac ttaccctttt ttcaataact tcattaactt 1861 tgttttcaaa accagttaaa aaagaaccga atatgaaaaa gttgattata gcagcaggac 1921 tactaatgac aacgtccgcc tatgcacaaa ccgaagtact gacaggggtt acccgaggaa 1981 aagactatgg agtggtttac agtcttccca aaacccaaat agaacttgaa ataaaagcca 2041 acaaagtcaa ctatactccg ggagaattca gcaaatatgc tgatcgttac ctgcgactga 2101 ccaacgtctc cgccgatcct gaagagtact gggaactggc tagcgtaaaa gtgaaatccg 2161 taggtgtgcc caacagcgaa actacgtatt tcgtaaaatt gaaggataag acagtagcac 2221 cgctcatgga actgacagag gatggcattg tgaaaacgat caatgttcct tacagcaaca 2281 gcagtgtaag caaaaaagtt gctcccgctc ccgcagtcct ccaaaagaaa gcgaatcctc 2341 gcgaattcct gaccgaagag attctgatgg ctagttctac cgccaagatg gccgagctgg 2401 tggctaaaga gatctataac atccgcgaaa gcaaaaatgc cttattgcgc ggacaagctg 2461 ataatatgcc ttcagatggg gcacagctta aaattatgct cgacaatctg aatgcacagg 2521 aagaagccat gacacaaatg ttctccggca cctgcaacaa agaagagaga acattcactg 2581 tccgccttac ccctgacaag gaattcaaca atgaagttgc tttccgcttc tcgaagaagt 2641 taggtgtagt tgccaacaat gatttggcag gaactccgtt ttatatcagt ctgaaagacc 2701 tgaaatcggt caagatgcca caggaagatg gtaagaagaa gaaagatttg gatggaatcg 2761 cctacaacgt acccggacaa gctatggtta cactgaccga cggtaaaaag aaactttacg 2821 aaggtgagct tcctattacc caattcggtg tgatagaata tctggctccg gttttgttca 2881 acaagaattc taccatcaaa gtttattttg atccgaatac gggaggattg ctcaaagtgg 2941 acagagaaga agggaaatag aaaaacgagg aagtaaactt ctaaaaaaaa agaatatggt 3001 tggtgaagga catgcattcg acatgatacg ccgaataaaa gagggacggg aagcttcccg 3061 cctacgtcgt gaacgtgcta acgataagtt gaagcatcta aaccgtgcaa acgaacctta 3121 tccactaccc aacaccaccc ccgaagaaat ggaacgtatc atccacgact cggagaaaaa 3181 gaaagagaaa gacagcaatt attttgtttg gggaacgctt attatcatgg gggtcctgat 3241 agcaattgcc gtcatacttt gggctgtatt tatcaaataa ataataataa gttcctattt 3301 atacgactgg tatcaccagt tttataaatc catctttctg catttgagaa agataagccg 3361 atacacgcga ctcgtagccc tcttcatttt gaaagtggtc tgcgagtttt tctataatct 3421 cacgaacatt gcgttttcca tctatcagtt cccatacagc cgtaccgtgt tcttccaatt 3481 tcacatgaag ttctttcgac attcctttcg gcacaaggaa gcgttgcatc cacggatatt 3541 taaaacgggg aaaggagagc acaattgtct ccccttccct ttctgctgta atatgttcac 3601 tgcgacaggg aatgacctct aacaggttga ttttctcttt ggcagccata cttcttattt 3661 tttatttcag agtattcata ctgatactct tctgtttaca ccttgataca aaattccttt 3721 gtcactttag gtattgaatt tcctagttac ttttggatat tcgcctcttc caaaccgtat 3781 cccttcttct tgttctctgc cttcaacatc aaagccacaa tcagagcaag cacaccaaaa 3841 agagcaaaaa tagtcatcgg caacgtgtag tcataagtct gtgcaccgtc tactaccgga 3901 cctttgcaat aagtattcaa cacccatccg atcaacaaag gaacacccat caatccccag 3961 ttctgtaccc agaaaatcaa tgcgtatgct gtacccaact gtttttccgg aataatcttc 4021 ggaacagacg gccacatagc tgaaggcacc aacgagaagg caaaccccaa tataatcatg 4081 atgatagtag caaaccacca tatattcagt ataggcagag caaacatcgt atgcacaaaa 4141 ataagcatca ctgatccgat tatcatcaat gtggctccct taccaatacg gtcataaagc 4201 gagccgaaca acggagtcag aataatcgca ccaatcggca acaatccggg aatcgttccc 4261 gccaacttcg gatctacatt atacttctgc accatcaagt cggcagcata cttgataaag 4321 gggaatacag ccgagtagaa caatacacat agtaatgcaa tcagccagaa tcctttattg 4381 gtaatgatat acacaatatc tttcatacgg aacggctctt ccggttccaa tccctctgca 4441 tccaaagaag catccaactt cttatcatag aaagtataaa gaaagaaagc aatcgtaccc 4501 acgcacaaca taatcagaca aaacaaaatc ggagtaggaa tattggtatg gaatgtgcca 4561 ctctcatccg tagatccgaa aaagtcggcc aaaggaaccg taagcaccat tgccagagtt 4621 gttccgatac gtgccgtagc catttcaagt cccatagcca acgccatttc cttacccttg 4681 aaccatttca cgataatctt ggaaactgtg ataccggcaa tttccacacc tacaccgaag 4741 atagcatacc ccaatgcagc cagggttacc tgtgttttga atccgaagag catggcacct 4801 tccggaaaag tagtagaaat cgcatagtat ttcaatccac aaccaaacac catcaataag 4861 caagctccca ttccggtgaa acgaaccccc atcttatcca aaatgatacc accgaagatc 4921 agcatcaaca ggaatacatt aaaccatccg taagcgcttg tgaagaaacc ataatcaaga 4981 ctgtcccata gtagttcttt ctcaagcatg ggttttagag gagacattac gtcggtgagg 5041 aaatagccgc atagcatagt aaatgcgact aatgctagaa cactccatcg gagtacggcg 5101 gagtcattca atttctgttt caaatgttct gtcattgtta tatttaaaaa tagtagttaa 5161 taatcttata cagccaacaa aggtagttaa atctcgtttg tttctatcac aaagagattg 5221 tttttacaag aaaaagttaa gtgcggatta cactgaccac gcggaagatt gaaaatccgt 5281 gtaatctgcg taatccgcac ttaaatatca aagaaatgca gcatccgtct gcaccttccc 5341 attaatggtt ttaccccaaa gtcttacctg acaacggagt gaattactct gctgcaggag 5401 caggagtttc agcagccggt gccggagttt ctgtagcagg tgcattggta gcaggagctt 5461 cagtttgcgg cgcagccgta cctgcgggta agttatacgg gttagtctgt tgttctttct 5521 gtgcctgttc caacactgcg tctttagcaa cagcagagcg aggaactaca taagcagtag 5581 caatgctcat taccaccatg aagatagcta agccccatgt tgctttttcc agaaaatctg 5641 tagtcttgcg cacgcccatg atggcgttag atgaagagaa accagaagca agtccgcctc 5701 cttttgagtt ctgaatcagc acgatgaaac acatcaacaa ggctgcaata accattaaga 5761 taacgaataa taagtacatt tttagttatt ttgaattagc gttaataatc aatttctcca 5821 aaaatctgat ttggtctgca aagtaagcat ttttttttgg atatttcaag cttaattttt 5881 taattatttc aagagctttt gaatatcgtt gctgtttaac atagattttt gccaaagttt 5941 ccgtaaaaca gctgtcatct tcctcttctt ccttcatcgt ttcttcttcg gtaagttcgt 6001 ccgaagaggt tggcgaagat ggcatttctt ctcttaaagg tttcttgcag aggggagagt 6061 cgctctcgct cttttctata aagtcgtcaa tcagttcgta gcctttgagt ttgggcgttt 6121 cttcggccga ctgttccgtg gccggagtct cctccaaaag ataagaggtg taatccatcg 6181 aatagtcgaa gctggtgcgg gcagtcacct cttcgggtac tgtggacaag aaagcgtcga 6241 tcaatgctaa tgtgcggtct acggacggtt cgtctttcaa cacctccgtg agaggtactc 6301 cctttttccg tgcctgcaca tcatagcggt caccttcaat caaccggaac aactgccgtc 6361 tgtctgcaat gtaaagaact gctttccgca gttctccacc gaaactaata tcatggagaa 6421 tatacagatt cttcagatac agcagacgaa gtgactgaaa atacggatac ctcgcaagaa 6481 gattgcgcag ttcgtacaaa gtatccctat tcagcgtctc gggatgctga atccattgtt 6541 gaaagttaac agaagtcatt tatattacca gtttgctaca gttgcattaa aaatttggtc 6601 ggtgatctct ttagacattt cagcaatcaa tccgtcctgt acggcagtca gcaactggct 6661 agagtcgtag gtacggaacg cagaaaactg ttgttcaaag tcttcggcat gattggtgtt 6721 gttgacaaaa cgtacattga cggtaatagt caacttcgtc tccgaagaat aaccgtcggc 6781 agatactgcc tggttgtact gattgtaacc tgtgatttct ccgtcaatct gcaagtcggc 6841 attctgattc ggcttgagca gttgcagacg ggtctgccgg atgaagatat ctttcaggtc 6901 ctcattgaat ttggttgcca acggagcata tacatactcc gacttgatcg ggaagtcggc 6961 tatcgaaatg gtctttacct tatcataatt gatagacgat ccgttaaact tataggaaac 7021 agtgcacgca atgactacca acggcaagcc gaacagtaac aaagggcgta ttattttctt 7081 aatccaattc atattctttt atttttctat aaagtgtacg ctcggaaata ttcaagtcct 7141 tggccgcact cttccgcttt ccatgatgcc tctcaagtgc tttgcgtatc atttctttct 7201 ccacttcgtc cagtgacaaa ggagattctt ctacatattc ttccgtgtct tgtatgtcat 7261 catcatcctt gcaaaccgtg ggctgcatgg tgtgaatgat agcaggtacc gaaggttgat 7321 gcgccgtcac taccggagta gtaaccaccg ttcccatttg tcctacctgc cccacctgtc 7381 cggcacgttc cgccatcagg ttgtgcacca tcttcttcag ctccgccact tcctggcgca 7441 tatcgaacag aacagaataa agaatctccc gttcgctctc aaagccttta ctctcacgcg 7501 ttcccatcag cgcgggaaga cgttgcgtat tttgtgcggg aagataattc tgcaagatag 7561 cagcagagat ctccctattg gtttcaatga tagatatttg ctcggtgatg ttcttcaact 7621 gacgcacgtt tccgggccac gggtaagcta acaactcttt cttcgcatcc tccgtcaact 7681 gaatagcagg catccgatat ttctctgcaa agtctgcgga aaacttacgg aacaacaaaa 7741 gtacatcgtc accacgttca cgcaaaggcg gtatttggat aggcaccgta ttcaaccggt 7801 aatataaatc ttcacggaaa cgtccttctg caatcgcttg tgtcagattg acgttggtag 7861 ccgccaccac acgcacatcc gttttttgta ctttggacga acctactttc ataaactcgc 7921 cactctccag tacacggagc aaacgtgcct gggtagacat cggcaactcc cctacttcat 7981 caagaaaaat agtaccaccg tcagcttcgc caaagtaccc tttccgttcg ccaatcgcac 8041 cggtaaacgc acctttctca tgtccgaaca gttcggaatc aatcgtacct tccggaatag 8101 cgccacagtt gacagcaata tactgtccgt gcttcctccg gctatattga tgaataatct 8161 gcggaaaact ttcttttccg actccacttt ctccggtaat cagcacagac aaatcggtag 8221 gagctacctg aatggcaaca tctatggcgc gcgacaatgc ttcagtattt ccaataatac 8281 cgaaacgctg tttcacttgt tgtatctctg ctctcgtcat cactcgtttt taatcttcgt 8341 ctactgtatc cagcttcagt ttatcactat cgtcacgttt ctcgtaatac tgtttacgca 8401 acggattggc acgagccact ttttcccgct gacgattacg gaacacgtcg atggcaacat 8461 agattgcctg gcggaaagaa tcttcacaag ccactccctt acctgcaata tcgtatgccg 8521 ttccatgagc cggagaagta cgtactaccg gcagtcctgc cgtatagttc accccgtctt 8581 ccatagccaa ggccttaaac ggagccagcc cttgatcgtg atacatcgcc aggataccgt 8641 caaaatgagt ataattgcct gaacccataa agccgtcggc cgcataagga ccgtagcaaa 8701 ggattccttt ctcttccatt tctttcatgg cagggataat cacttcctgc tcttccattc 8761 ccaacaaacc accgtctccg gcatgaggat tgagagaaag caccgcaata cgcggagcgc 8821 cgataccaaa atcctgtttc agacaacgat ggaatatcat cagtttctcc tgaatcaatt 8881 ctttggtaat cgtagtcgcg atctctctga cagggatatg tgtcgtcacc aaagccaccc 8941 ggaagtcatt cttcatcaaa atcatcaatg acttatcacc attacccaga cgttcttcga 9001 tatattccgt atgtccgggg aaggagaact cttccgactg aatcgtatgt ttgttgatcg 9061 gagctgttac gataacgtct atcaaccctt cgcgatattc ttcgatggca cgttccaaag 9121 cccccaacgc agctttaccg gcttcgggat cgggtttgga aaattccact ttcacctcat 9181 catccgtaca gttcaccacg ctcaaacggt tgtaccccgc ctcggtagca gagttgacaa 9241 tgctaaaatt ggcctgtata tccagcgctt tgcgatgata agccgctact ttcggtgagc 9301 cataaatgat cggagtacat agttccaaca tcgtagggtc ggaaaatgtc ttaagaatca 9361 cctcatagcc caccccgtta atatctcctt gggtgatacc tatccttatc ttgttatctt 9421 ccatgttttt atttattagt ttgttccgct tccttagatg cttctcccaa tggaatctgc 9481 ttctgctgaa cttcattcgg aagtttcagt gtatacagag atgcttccat ctggcgtacc 9541 aggttgcgtt tcattttatc aggtgaataa acaaatattt ctgctgtaat aattcgttgg 9601 tttttctcgt ccaaacgagt gtgagagaca tacggaccac ccataaagtc gcccttcata 9661 cgccacaggc cacgtgcttc cattgtgtag ctgttctgca cattgatcgg acggacatcg 9721 gtcagcaaac tatcggtcga catataaacg ccttccttga atccggggat attggctttc 9781 atcacagagt cacgtttgtg cacaaaatat tctttggtaa acgtatcctt gtcagtgtac 9841 ggataagagt acatcacaaa gttacggtcg gcagtacctg tgttggtaga agcccagaag 9901 aaatcatccc cggtctttga attagccagt tcggcatcca cccagatgtc gcatccgaac 9961 aaactgtcca ctttctgcga aatgaagtta ctgtgtttcc cttccaggaa cgtaatctga 10021 cggttcattt ccgcacgggt aaagaagtcg acaatcgtct ttttgttctc ttccacaaac 10081 ttctcgaact cttcttcgtt cggagcctgg atagtcaata tcatctgcgg attggcatac 10141 acgtccttcg catatttgaa cgaggctttc gtatatatat cctgtatatc tacaataata 10201 atgttacgta tcaacttcag cgtagaatca taatctttcg gtgaagtata cataatccgg 10261 aaagaaggtt ccgactgcgg caaaccgggc atatcagcat cgagcgcatc atgtaaagcc 10321 cttccggcag cacgatccca aacaccgtga tctactacaa ccaaaagctc gtaagcacga 10381 ccactagagg tgtgatttcc tttcagacca caagatgcaa cgacaaaggc taccaaagcg 10441 atgcataaaa taaaagagta ctttttcatg atgttcggtt ttatatatta actttcatta 10501 tttttctcct gtttcgctgt cgacagcata ccgcaagcgg caaaaatatc ttcgcctctg 10561 gatgaacgga tagtggtgaa aagtccgtgt gacgtcagat aatcacgaaa acgggtcatc 10621 gtatccatgt ccgccccctc aaggtctacc cccggtatgg catgaaaacg aatcagattc 10681 accctgcaat ccagcccgcg aagaagtttc agcaactctt tggcatagac ctgcgaatca 10741 ttgagccctt taaaaacaat atattcaaac gaaagtcgac gttgtttact aaaatcatag 10801 ttttttaaca gttccaccat ttcggtgatt gaaaacgcct tttccgccgg cattaattca 10861 gcacgctgaa cggtcagcgg agagtgaagg ctgatggcaa ggtggcagtc attttcttcg 10921 ataaaacgct gcaatccttt ccgtagcccg acagtagaaa gcgtgatacg cttcggactc 10981 catgcgtaac cgtaggtagc ggtcagtagt tccaatgcct tcaatacctc atccaggtta 11041 tcgagcggct cgcccattcc catcattacg acattagtca gtttgtcccg ttccggcagc 11101 gaatgaatct ggttcatgat ctggctggcg gtcaggttag ccgtataccc ctgtttgccg 11161 gtcatacaga acttacagtt cattttgcaa cctacttgtg acgacacgca caacgttgcc 11221 cggtcatcat ccggtatata aaccgactct acaaaatggt tctcacccac tttataaaga 11281 tacttcaccg taccatctac agagcgcatt tcatctaccg gagcttccgc tcccacctca 11341 tagttctgct tgagcaactc ccggtgtttc aatgacaaat tagtcatatc atcaatcgag 11401 gctaccttct tttcgtaaag ccaggatgca atctgcttgg cagcaaagcc gggcataccc 11461 agtctttttg tcaatgattg aagctctaca agagtcattc ctaaaagggg atatttagac 11521 attcttcttt ctgttgatag tttatatctg caaatgtaag gaaataaagt cgatttccgt 11581 atagcaggaa tgtaaaagtt aacaaaaaag ggaagtatac ccaagttatt atttaacaaa 11641 gctgatatat tgaagtagcg ttcgcgccaa ttcagagtcc tcgccattcc gtttcacttc 11701 gtgaccatac gcctcacgga aacaagccag cgcatctttc cgttcataac aatatttgtg 11761 taaaacccct aagttttgac aagccacaat cgtatcttca ttctcccatc cctgatgctt 11821 ctttcgcagt tcaaactctt tgaagaaagc cgctttcgcc attggataat ccttcttttt 11881 cgtataagcc agtgctttgt agtaatatac cagacaggaa gaatcggggt caccatcatc 11941 atgaatatcc agggaggttg ctatacgaat cacattatca taatctttat tcatgtaata 12001 ttgctgcata atatcacatc ttaatgcctc gtaacggata gtcaattctg ccaaacgagg 12061 cttttcgctg aaaaacactt catgcagaag agactcatgg aagaataaag tagcggcctg 12121 ctcatcgtta cgctcattca ttatgcgttt gaattctatg catagataat acaactgttt 12181 atgacaagcg actatctgct ttctattatc tatctgcata gaaatatcca atgcccgatt 12241 catcagattc cacgcttcat cgtattgctt aacacaataa agacatctac cttgcatacg 12301 catgcattta gccactccac ttgacaatct accattcaaa gattcgtgca ttttagctac 12361 tttccggaat tgttcggccg cactctcttc gtttttctta taataatcgc aataagccag 12421 cagttcgtaa agttcaatga tttctgccat attattctcg tcagtagaag ccgcatgata 12481 gccaagcgct ctatttagat aagtcaccgc ttcattatat tgcccattat aataacatgc 12541 catccccaaa ttcctacatg tatcagtaat ctggggtacc ggaatcggta ctatattttc 12601 ctgcatcatc aatgctttca ggaaacaatc acatgccatt tcatattctt cgtcacgggc 12661 atagcgacat ccctcgttca ttttcagcac tgatctggca attggcggta tggcagctcc 12721 ttccatacat ttctcactca caacatttgc tacctttgtc aggtgaaaag aacgacttaa 12781 gaaagtagct atatcattag caatgacagg aatcaaaaaa gaatcaacct gaccaaagtc 12841 cgattcggca tagacatcag gcataaaaga agagtcgtcg ctcataagtg ccttccagca 12901 atcttccaac aaagaataat tcgtacgata cagaatttcg aagagttcta catcacaaat 12961 ccactttctc aagaaattcc gctcctgcat cttataacct tgataagtaa tttccacttt 13021 atagcgataa gaatcatggt agcagaactg tttcatacga tagctataat cagcaaaagt 13081 cagttggtgc gaaaggatat cttcattgtc cagaaaagag gttattattt tatgacgaca 13141 cttatcgatg cacatatcgc cttgagcgaa gcatcgttta atcgcctcta ccatttgtgt 13201 gtcacaaata caatatcgcc ctcctttgtt ggtgagccag ctactcattt ccactttcaa 13261 ctgtgaccaa agcatctgat ttatgcctgc catgctcttt acttcatctt cggtaaatcc 13321 ttctaaagta agtgaaagca tcagaagcgt tcttccaatc tcttcgaaac cataatcagc 13381 cgacaaacgc cgaagcacac tgtcataaaa ttgctcaacc tcattgagcc ggcaatatcc 13441 actcatatat tcatagagag catcgtactg accgaacgaa accagctcat tgagcaatac 13501 acttaaacag cgcggttgtt tagccagcac ccacgaacca agaatatctt cctgctgtgc 13561 agacaaggtc ttggagtaag cagacaaata ttgttttgag aactccttag catccacttg 13621 tgaaaaacca ttcaactgga aatgaacgt //