LOCUS       c00001_gnlPro..        24638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OKGLHIPJ_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:29:31
            Original ID  :: gnl|Prokka|OKGLHIPJ_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 43424
            Orig. end    :: 68062
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24638
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[53424:58062]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14638
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24638
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24638
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(1044..3776)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_27"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3.8e-07, bitscore:
                     22.9, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPALTYYALLVLLLASCFSCKTDSEKKKFVIGVSQCTLEGSWRK
                     SMLLDMKVQASEYPGVSLLVEDAADSSLLQVEQIRSLIKRKVDLLIISANESEPVTPIA
                     IEAYRAGIPTILVDRKISSDEYTTYIGGNNYEIGRQAGFFVNRQVKEKYPTVLEVWGLS
                     GSSPAQDRHRGFMEVLNSRIKVKEIFGKWKPETVEKEIAEMDSLEEVDVVFAHNDVMAM
                     AARRAIERMHPGLADRISFVGIDAVSGRGSGLEAVMHGELAASVLYPTGGSLAIRVAMQ
                     ILNGEDVSRQYLLSSALIDKNNAGTLFIQSEQVVDYQHQIELQRENLESMLSKYTFLQN
                     SVGIILLLMGMLLLSALYVVHVNRAVKRKNRELKRTNLQVQQQKEELAEANRYIEKSTA
                     QKLQFFTNITHEIKTPLTLILGPLGKLSKEAPEGSSLADDIRIIRKNAERLKRVVDQLL
                     DFRKVESNKMNMRVGEVDLVAFVAEVKSYFDTMAATKQIHFTFEHDCPSVNIWVDRDKM
                     EKILANLLSNAFKFTLDGGTVTIHLKDKGDQVELSVEDNGKGIPSENIASVFDRFFTGD
                     QNYVTGTGIGLHLTREFVHMHKGTIRVESVPHKSTVFTVILLKGKSHFDESCTFDLSVT
                     ELSSGVADLNTDELQEVLNRTYNYTVLVVEDDLDIQSYLQAELKQNFRVLVADNGVKAL
                     EVLMSEEVSMVISDVMMPEMNGFDLCRKIKSDIVLSHLPVMLLTALSDDKQQMYGAASG
                     ADAYIQKPFNIEVVKLRIIKLLEDRVRLREAYARDASSPAVSVKEEKAGSMDDLFMNRF
                     LKLIEESYADPDFSIEKGSEKLGLSRVHLYRKVKELAGVTPTDFLRNYRLKKAAALLRR
                     KAGNVNEVAYATGFGSPAYFSKCFKAVYNITPTEYLEKE"
     CDS             3873..4340
                     /locus_tag="ctg1_28"
                     /transl_table=11
                     /translation="MKIINEALLNETTGRAKQSPRLRMNYNFHEHLDDPVNRLLNALEP
                     GTYLRPHRHLNPKKDEIFLLLRGRIAVFLFDNKGEITQTQILDPKEGVYGAEIKAGTWH
                     GLLVLESGSIIYEIKEGPFAPLAPENFAPWSPAPEDTKGVAKYMELLGKAI"
     CDS             complement(4558..6387)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_29"
                     /sec_met_domain="Peptidase_U32 (E-value: 6.9e-73, bitscore:
                     237.7, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTKSRPIELLSPAKDLNCGIEAINHGADAVYIGAPKFGARAAAG
                     NSLEDIRELCEYAHLYGARIYVTLNTILKEDELEEAERMIWDLWRVGTDALIIQDMGIT
                     RLNLPPIPLHASTQTDNRTPEKVRFLEAAGFTQVVLARELSLNEIRRISEATTVPLEVF
                     VHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYTMVDATGTEIVTHKHLLSLKDM
                     NRSDQLEALLDAGVSSLKIEGRLKDVGYVKNITAYYRKKLDAVLSRRPEYRRASAGRST
                     YTFEPVAEKSFNRGFTPFLLEGRTADITAFNTPKSLGEPVGTVKEIKGNSFTVAGLKQL
                     SNGDGLVFFNRKGELEGFRVNRVEANRVFPLDMPQLTPKTPLYRNFDQAFDKLLAKPSA
                     ERKLSVEIEFLDNPFGFTLCMEDETGARIMLTEPFAKELARRERQDNIRTQLSKLGNTP
                     FEASKVVVGLSENWFVPSSLLADMRRRGVEKLLEARRARYPRETVKRVQPSVSIPFPER
                     QLTYLGNVANGKARSFYQDHGVEQIDPAFELSPRKDVPLMFTKHCLRYSMGWCPTYQKD
                     KSPYKEPYYLLYKDTRLRLQFDCKHCQMLVFES"
     CDS             complement(6410..7342)
                     /locus_tag="ctg1_30"
                     /transl_table=11
                     /translation="MPLNLQKNLPAVELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMP
                     LKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMKEFYKDFDEMQDDFYDGMI
                     ITGAPVEQMPFEEVNYWEEVTEIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAK
                     MFGVFRHTLREPYVPIFRGFDDEFYVPHSRHTEIRREDVMKVPDLTLLSESEESGVYMA
                     MARGGREFFITGHSEYSPYTLNDEYMRDVNKGLPIAVPRNYYRNNNPALGPVVRWRGHA
                     NLLFTNWLNYYVYQETPFRIEDISKLGDL"
     CDS             7451..9856
                     /locus_tag="ctg1_31"
                     /transl_table=11
                     /translation="MKIRAIATLLFILFSISAFGQGRAKISGYIRDADGNPLDLVNIRV
                     KNTLNGTMSNEKGHYSLSVATGDSVTLIYSCLGYNKAERILPQVTKDMRLNVQMNYTSL
                     ELGEVVATAIRKQTTTLETLNADRVKLLPDPAGGSIESLVVTFAGVTSNNELSSQYSVR
                     GGSYDENIVYVNGLEVFRPLLIRSGQQEGLSFINPDMTEAVNFSAGGFEARYGDKMSSV
                     LDITYKKPKGFEGSASASLLGANAYVGSSSGKFTQVTGFRYKTGRSLLKTTDTDAEYDP
                     NFIDLQTYMTYQLAPKWEINFLGNLAINNYKFIPHTRETSFGTATNAKKFKVFMSGQER
                     DKFETLFGALTLKHNLNDNTELGLQASAFTSKEEEGYDIAGDYWLGDAAEEGGGEIQKL
                     SIARYNEHARNRLHSNIMNVGHYGVARIKNNTLKWGATVQLEKINDKISEWEKRDSAGY
                     SLPQGGGNVNVIANLFSDNKLESTRISGYLQDVFKFRTKQGLFTLVGGVRGSYWSYNRE
                     FIFSPRASIGFIPNFDQNLTFRLASGLYYQSPFYKELRTTVQDEHGNSIIQLNKNLKSQ
                     RSIHVIAGGDYTFRASGRNFKVSADMYYKKLDNLNPYTVDNVKIRYYGENCAQGHAMGL
                     DVKFFGEFVPGTDSWISFSLMKAEQSIRGSEYVPMPNSQGYNVSLFFQDYFPGYKRVKL
                     NLKGVLSGGLPVTAPRTGYEDGYFRTPTYKRVDLGFSYQLAGGTDAIMDRGFFRNLKNI
                     WLGLDIFNLFDIKNTSSYYWITNIDNHQYAIPNYLTGRQLNIRLIVDF"
     CDS             10001..10408
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_32"
                     /sec_met_domain="Glyoxalase_4 (E-value: 8.7e-27, bitscore:
                     86.7, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEEVLGLKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALDEAESKGIKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGK"
     CDS             10521..12074
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_33"
                     /sec_met_domain="CT_Btheta (E-value: 1.6e-291, bitscore:
                     960.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALRETARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIYAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLISFLPQNNLEETPLIECKDPIDRLDDNLNDIIPDNPN
                     QAYDMYEVIGTIIDNGEFLEVHADYAKNIIVGFARFNGQTVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12090..12983
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_34"
                     /sec_met_domain="OAD_gamma (E-value: 1.1e-11, bitscore:
                     38.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMINKKIGVLLLFALLVSFGAKAQRATSMRINEVLVINEDNFVD
                     DYGKRHAWIELFNNSAGSVNIAGCYLTNDKSNPKKYPIPKGDVLTVIPPRQHTLFWADG
                     EPDRGTFHVNFTLDPSKENYIALYDADGRTLIDEIVIPASQKADVSYGRTLDGQGEWTA
                     LTKVTPSTNNVTLDSNEKIENFKENDSWGIGMTLTAMAVVFSGLFLLFIIFKQIGKLSI
                     AASKRNAQKAAGAAVIADNAGQESGEIFAAIGAALYEMSDDNHDIEHTVLTIRKVQRSY
                     SPWSSKIYGLREVPKK"
     CDS             13006..13437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.5; E-value:
                     9.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_35"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.1e-20, bitscore:
                     65.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHISSVVDDIAEVEVNGTPYQVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVISRPAASTTKGAVKSPLPGVILQVNCKVGDTVKRGQNLLV
                     LEAMKMENNINADRDGKIIEIKVNKGDSVLEGADLVVIG"
     CDS             13442..14638
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_36"
                     /sec_met_domain="OAD_beta (E-value: 1.6e-152, bitscore:
                     500.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSVLLQAAGTAHESFLQFLGENLELFLTYTGVYNATPGHLIMI
                     LVGLLFIFLAIKYEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTS
                     GWYPPLIFLGIGAMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGI
                     IGGADGPTAIFLSSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTQKERLIRMKPP
                     RAVSSTEKIVFPIVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDT
                     ITILLGITVGASTQATQFLTLNSIKIFGLGALSFVIATCAGILFVKFFNLFLKEGNKIN
                     PLIGNSGVSAVPDSARISQNVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(15259..17307)
                     /locus_tag="ctg1_37"
                     /transl_table=11
                     /translation="MHSRDMEYIVGLLKNGKDAEAILSVRRKLNMAFLARTTDLSGKLP
                     VLAFGSTFKKNGDGIQLRRYNGYVLLEVNGLESQSEAEAVRREAAALPQTLLAFVGLSG
                     RSVKIVVPFVLPDGSLPKKEEQARMFHAAAYQLAVRHYQPQLGSIISLKEPFLSRGCRM
                     SVDPDAYYNPDAVAIRIEQPLQMPDGGDLKIVPSSVRDPLEMMAPGADRNGQIATLFSV
                     ILMEMTRRFSESPEDDIQLLFIDLAQACCRLGIPEEEAVGWTLRYEALKKYKIDVRMAF
                     RTAYTLENVSNRAEPLSSVPPSMSLVLRLDEFMNRRYFFRTNEMSGGVEYLDRSMIQFV
                     YKPYTTKVRNSICLEAQQEGLNVWDKDIDRYVNSDRVPIYHPIDHFLGNLPAWDGKERI
                     RALAGRVPCDNPVWGDLFYRWFLSMVAHWMELDSEHGNSTTPLLVGGQGCGKSTFCLNL
                     LPPVLRPYYTDSIDFGNRRGAELALHRYALINIDEFDSVKSSHQSFLKHILQKAVVNTR
                     LPYQSASRNLRRYATFIATSNNYDLLTDPTGSRRFICVEVKGRIDYAQPIDYDQLYAEA
                     KELLRRGERFWFTPEEEALITENNRDFQQQPAEEQLFLRYFKIAEDIEEAKPLLASEIL
                     DMIAEKQPGFNITKTMILNFGKLLKRNSVPNKRTMRGTCYYVEEVDG"
     CDS             complement(17349..17735)
                     /locus_tag="ctg1_38"
                     /transl_table=11
                     /translation="MAHYYVVRQKLDKTGAEDKVRYYGVPVTCGRVSTKKLADLVADRC
                     SLSRGDVFASVCEIGGMILELLKDGYSVELDGLGDFYLSAGSEGFEDPKKCTPHRVKAR
                     RVCFRMAPCVRKSMKFVKFERNPW"
     CDS             complement(18338..19057)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_39"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.5e-23, bitscore:
                     77.0, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSCILNIETSTSVCSVALSMDGEVLFAKASFDGPSHAALLGVFVE
                     EALSVLKKKGKKALDAVAVSSGPGSYTGLRIGVSVAKGLCFGFGIPLIGIHTLDIMAAT
                     VNSKGDSQIVSITDDCLYCAMLDARRMEVYAAIYDASLKPVRETKADIVEAGTYASYLE
                     KGKVCFFGNGVSKCKSVITSPNAIFIEDIHPLAVNMIPLSEQAFAAGKFEDTAYFEPFY
                     LKEFQATVAKNKVLLAR"
     CDS             19281..20153
                     /locus_tag="ctg1_40"
                     /transl_table=11
                     /translation="MIQSMTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKEK
                     EMQIRSLLLQSLERGKVEFNIFVEYIGKDTPTQINLAAVENYYNQIKDIADRLNIGLPA
                     DWFQTLLRMPDVIKTEAQEVNEEEWNVVEKAIKEAIGHLCDFRIQEGAMLQKLFEQKIA
                     NISRLLSEVEPYEKERIEKIKARIMDNLEKIAGQDYDKNRFEQEMIYYIEKLDVNEEKN
                     RLDNHLKYYISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKLVVQMKDELEQ
                     IKEQVLNVL"
     CDS             20163..20732
                     /locus_tag="ctg1_41"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINFLLKQNLNLHFSISATSRAPRGTE
                     KDGVEYYFLTPDEFRARIAAGDFLEYEEVYTDKYYGTLKSEVERRLMSGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPSIEDLRSRLEGRGTDAPEVIESRIAKAEFELGFADKFD
                     VIVVNDKLEVAQKEALKVIKEFLKKA"
     CDS             20729..20902
                     /locus_tag="ctg1_42"
                     /transl_table=11
                     /translation="MNGKKLSKKWLYTFIGIAFVALATCTAALYYKEYIIATGTGLVFG
                     AQVINIIKWKRD"
     CDS             20887..21498
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_43"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-24,
                     bitscore: 79.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VETGLKENTVSKRKTGIYSGSFNPVHIGHLALANWLCEFTELDEL
                     WFLITPHNPLKEKEELMDDRLRYELVKKSIAGYPKFHASDFEFSLPQPTYTINTLRTLE
                     ASYPDREFYFIMGADNWKYITRWVEYEAIISNYPIFIYPRKGFDVEIPAQYPHIKKVDA
                     PLVEISSTFIREAFKTGKDVRFFLPEAIRNLPFPLQNNTF"
     CDS             21589..23319
                     /locus_tag="ctg1_44"
                     /transl_table=11
                     /translation="MNLLELSEQEIIRRNSMEQLRQMGIEPYPAAEYVTNAFSKEIKEN
                     FKDDAEPRPVSIAGRIMSRRIMGKASFMELQDSEGRIQVYISRDDICPEENKDLYNIVF
                     KKLLDIGDFVGIKGFVFRTQMGEISVHAQEITVLSKSLKPLPVVKYKDGVAYDGFNDPE
                     LRYRQRYVDLVVNDGVKDIFMKRAAVIKTMRTALDEAGYTEVETPILQSIPGGASARPF
                     ITHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMELYV
                     QYKDYNWMMSFTEQLLERICIAVNGTCESVVDGKTINFKAPYRRLPILDAIKEKTGYDL
                     NGKSEDEIRTICKDLNLEIDETMGKGKLIDEIFGEFCEGTFIQPTFIIDYPVEMSPLTK
                     MHRSKPGLTERFELMINGKEVANAYSELNDPIDQEERFKEQLRLSEKGDDEAMFIDQDF
                     LRALQFGMPPTSGIGIGIDRLVMLMTGQTTIQEVLLFPQMRPEKTVKKDTADKYVALGI
                     DEAWVPALHKAGYLTTDTLVDANPNKLRQELCEMNKKYKLELQNPTAEEVEAWIAGAAK
                     "
     CDS             23330..24325
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_45"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 8.3e-33,
                     bitscore: 106.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDQVEEFLL
                     LGHNPSYLSAVKFDTDKIKFYTDINKVIKDSDTLIFATPSPFLKQHLMKVTTSMQDKFI
                     ISAIKGIVPDENMLVADYFAEYYNVPIDNIAVIGGPCHAEEIALERLSYITLACPNIEN
                     ARAFSSVFKNQYLNNSCCKDVTGIEYASVLKNVYAIVAGICHGMKYGDNFLAVFICNAI
                     EEMRNFLNAVHGLERDVTDSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKIAQLEMEM
                     IAEGYYGTKCIREINEKYKVNMPILDTLYSILYEKKSPTTAIRQLTETFK"
ORIGIN
        1 tgccggccat gccccctctt tcgtacagac ataagcagct gtgcggacgg caaattcatg
       61 cgcttccctt agcgaagccc ctttcaacaa cgaaatgacc agtgctccgg agaaagcatc
      121 acctgctcca accgtatccg ccacctgcac ttccggggtt tgcaaagtcg attcttcatt
      181 agcggtatat atcgtactat aagctcctcc ggccgtcaga accaccaagc ggagattata
      241 gtgttctata aaccaatgag ccacctcctt gtccgttcct tccaaatgaa acatatcccg
      301 caggacgacc aactccccat cattcacctt caacatattt gctagataaa gcgactcttc
      361 gatcaactct ttcgtataat aatgctgacg caaattgatg tcaaaacaac gataagcatc
      421 gtccggagca aaagaaagaa tcgcttgtat cgtctctctc gactgtgcgg aacgctgtcc
      481 taacgtaccg aagcaaatgg cacccgcccg ttcggccaaa tcaatcgcat ttgacgtcgg
      541 agaaagatga tcccaagcta cacgttcatt aataatatag tcagggacac catcctgcag
      601 agtaacctgt accgttccgg tcggataagg gactttctcg atcagatacc ggatcgaatt
      661 attatccagt tcttcgagga tttcgcgccc cagcccatcg tctcccacgg cgctgatagc
      721 atatccttcc gcccccaacc gcgacgcatg gtagacaaaa ttgataggag caccacctgc
      781 tttctttcct gttggcaaca tgtcccacag gagttctcct atgcctacta cgaccggttt
      841 cttattgttg ctttgcattg tttcattata gtttatttga caaggataat ttattatcta
      901 cgatgcaaag atagagacag gtagcagatg cgacgataac taatgctaca agattgataa
      961 cacttgttac attatactct tattttcgag ttacatgcac aagtgttaca caaatgtaac
     1021 gagcgttatc aaagagaaga atattattcc ttttccagat actccgtcgg agtaatattg
     1081 taaacggctt taaaacattt cgagaaataa gcaggcgaac cgaagcccgt cgcataagcc
     1141 acctcattca cattcccggc tttccgtcgg agtagagcag cagctttctt caaacgatag
     1201 ttacgcagga aatcggtcgg tgtcactccg gcaagctcct tcaccttccg gtaaagatgc
     1261 acacgcgaca agcccaattt ttcactacct ttctcaatac tgaaatccgg atcggcatag
     1321 gactcttcga tcagtttcaa gaaacgattc ataaaaagat cgtccatgct tcccgctttt
     1381 tcctccttca cggaaacagc aggcgaagaa gcatcgcgag cataagcctc acgcaaccgg
     1441 acacggtcct ccagcagctt gatgatacgc agtttcacga cttctatgtt aaaaggtttc
     1501 tggatatacg cgtccgcacc actggcagcc ccgtacatct gttgcttgtc gtcggacaaa
     1561 gcagtcaaca gcataaccgg aagatgactc aggacaatat ccgacttgat cttacgacaa
     1621 agatcgaaac cgttcatttc cggcatcatc acatcgctga taaccatcga aacctcttcg
     1681 ctcatcagca cctccaaagc cttcacgccg ttatcggcaa ccaacacacg gaagttctgt
     1741 tttaattccg cctgcaagta actctgtata tcaagatcat cttctacgac cagaacagta
     1801 taattgtagg tacggttcaa aacctcctgc aattcatccg tgttcaagtc ggcgacacca
     1861 ctggaaagct cggttacgga aagatcgaat gtacaagatt cgtcaaaatg agatttacct
     1921 ttcaagagga tgaccgtaaa gacagtactc ttatgcggaa cactctccac ccggatcgtg
     1981 cctttgtgca tgtggacgaa ctcacgcgtc aagtgcaggc cgatccccgt tcccgtcaca
     2041 tagttctggt caccggtaaa gaaacggtca aagacggaag caatattttc cgacggaata
     2101 cctttgccat tatcttcgac agaaagctcg acctgatctc ctttatcttt cagatggatc
     2161 gtgaccgtac ctccgtccag cgtgaacttg aatgcgttgg acaaaagatt ggccagaatc
     2221 ttctccatct tatccctgtc tacccatata ttaacagaag ggcagtcatg ctcaaacgtg
     2281 aaatgtatct gcttggtggc agccatcgta tcgaaataag atttcacttc tgccacaaaa
     2341 gcaactaaat ctacctctcc gacccgcata ttcatcttat tgctctctac ctttcgaaaa
     2401 tcaagtaact ggtccacgac tctcttcaat ctttccgcat ttttccgaat gatacggata
     2461 tcgtctgcca atgaagaacc ttccggagcc tctttcgaca gcttgccgag cggaccgagg
     2521 atcaacgtca acggcgtctt gatctcgtgt gtgatattgg taaagaattg cagtttctga
     2581 gccgtcgact tctcaatata acggtttgcc tcagccaatt cttctttttg ctgttgcacc
     2641 tgcaagttcg tacgtttcag ctcgcggttc ttccgcttca ccgcccggtt cacatggacc
     2701 acgtacaagg cggacaaaag caacatcccc atcagcaaaa ggataatgcc gacggagttt
     2761 tggaggaacg tgtatttgga aagcatactc tccaaattct cccgttgcaa ctcgatctgg
     2821 tgctgatagt cgaccacctg ttcggactgg ataaacagcg ttccggcatt gttcttatcg
     2881 atcaaggcag aagatagcaa atattgccgg gacacatctt ctccgttcaa tatctgcatg
     2941 gccacacgga tagcaaggct cccacccgtc ggatacaaga ccgaagcggc caactctccg
     3001 tgcatgacgg cttccagccc cgatccccgt cccgaaacgg catcgatccc cacaaagcta
     3061 atcctgtccg ccaatccggg atgcatcctt tcgattgccc tgcgggcagc cattgccatc
     3121 acatcattat gggcaaacac aacatccacc tcctccagcg aatccatttc cgctatctcc
     3181 ttctccaccg tttccggctt ccatttcccg aatatttcct tcaccttgat gcgggagttc
     3241 aaaacctcca taaaaccgcg atggcgatcc tgcgccggag aagaaccgga caagccccat
     3301 acttccaata cggtaggata tttctctttc acctgtcggt tcacgaaaaa gccggcctgg
     3361 cgaccgatct cgtaattgtt accaccgata taagtcgtat attcgtccga actgatcttc
     3421 cggtctacca ggatagtcgg aatgccggca cggtaggcct caatcgcaat aggagtgaca
     3481 ggttccgatt cattggcgga gataatcaat agatcgacct tacgttttat caggctgcgt
     3541 atctgctcca cctgcaacag actactgtcc gctgcatcct cgactaacag ggagacgccc
     3601 ggatattcgg aggcctgcac cttcatatcc agcaacatcg atttacgcca agaaccttca
     3661 agcgtacact gcgagacgcc gataacaaac tttttcttct ccgaatctgt tttgcaggaa
     3721 aagcaggatg ccagaagtaa gaccagcaga gcgtaataag ttagagcagg tttcattctg
     3781 ttttatttac aggtttctgc aaatgtacgg agaaatggca taccagccaa tatttatttt
     3841 gtacattcgt cctccagtaa tcaattattc gcatgaagat cataaacgaa gctttattga
     3901 atgaaacgac cgggcgtgcc aaacagtcgc ctcggctacg catgaactac aactttcatg
     3961 agcatttgga cgatcccgtc aaccgtttgc tcaatgccct ggaaccggga acctacctcc
     4021 gcccacaccg ccatctgaac cctaaaaaag atgaaatatt cctcctgctg cgcggtcgca
     4081 ttgctgtatt cctctttgac aacaaagggg aaatcaccca aacacagata ctcgatccga
     4141 aagaaggtgt ttacggcgcc gaaataaagg cgggaacatg gcacgggctg ttagttctag
     4201 aatccggctc tatcatatat gaaatcaagg aagggccgtt cgctccgctc gctccggaaa
     4261 atttcgctcc ctggagtccg gctccagaag acacgaaagg ggtggcaaaa tatatggagt
     4321 tattaggaaa ggctatataa ccttgcacta ccttcccgtt ccccttaaag aaaactttat
     4381 tttcatgcaa gggaaacttt attttcatag ggatgaaact tctttttcat ccccatgaaa
     4441 ctgttatcac atacctatcg gctcctttat tgctggaata cttttgtcaa acggatcatg
     4501 gcttctttca ccggacagtc attcttatcc gttctgacaa tagcgttctc ataattttca
     4561 actttcaaat accaacatct gacaatgctt gcagtcgaac tgcaaccgga ggcgcgtatc
     4621 tttataaagc agataatacg gttccttgta gggagacttg tctttttgat aagtaggaca
     4681 ccaccccatg ctgtagcgca ggcagtgttt ggtaaacatc aacggaacat ctttccgggg
     4741 agacagttca aatgccgggt caatctgttc caccccgtga tcctggtaga acgaacgggc
     4801 tttcccgttg gcaacattcc ccaaataagt aagttggcgt tcggggaaag gtatcgacac
     4861 ggacggctgc acacgtttca ctgtctcacg aggatagcgg gcacggcgtg cttccagcaa
     4921 cttctccact cctctacggc gcatatcggc aagcagagaa gagggaacga accagttttc
     4981 agacaaaccg accaccacct tcgatgcctc gaaaggcgta ttccccaact tggatagctg
     5041 tgtccgtata ttatcctgcc gttcacgacg cgccagctct ttcgcaaacg gctcggtcag
     5101 catgatccgt gctcccgtct catcctccat acaaagcgta aaaccgaagg gattgtccaa
     5161 gaactcgatc tccacggaca gcttgcgttc ggctgaaggc ttggcgagca gtttatcaaa
     5221 tgcctggtcg aaattgcggt aaagcggagt cttgggggta agctgcggca tatccagcgg
     5281 aaacacccgg tttgcctcca cccggtttac acgaaaacct tccaattcgc ctttcctatt
     5341 gaagaaaaca agcccgtctc cgttgctcag ctgcttcaag ccggccacag taaaagaatt
     5401 gcctttgatc tctttgaccg tcccgacagg ttcacccagc gatttaggcg tattgaaagc
     5461 ggtaatatcc gccgtccgtc cctccaaaag gaacggggtg aacccacggt taaaactctt
     5521 ttcagctacc ggctcgaacg tataagtgct tcgaccagca gaagcacgac gatattccgg
     5581 acggcgggac aggactgcat ctaacttctt ccgataataa gccgtgatat tcttgacata
     5641 gccgacatct ttcaaccgcc cttcgatctt gagggaagaa acacctgcat ccaacagggc
     5701 ttccagctga tcggagcggt tcatgtcctt gagcgaaagc aagtgtttat gggtgacgat
     5761 ctccgtccct gtcgcatcga ccatcgtata gggcaggcgg caatattggg cgcattctcc
     5821 gcgattggca ctacgtccac tcaaagcggc gctcagataa cattgcccgc tatagctgac
     5881 gcagagggcg ccgtgcacga atacttccag cggaacggta gtcgcttccg atatccggcg
     5941 aatctcgttc agcgacaatt cacgtgccag aaccacctgt gtaaagcctg cggcttcgag
     6001 gaaacggacc ttttccggtg tacgattgtc cgtctgcgtg ctggcgtgaa gcggaatagg
     6061 aggcaggttc agccgggtaa tccccatatc ctgaatgatc agggcatccg tcccgacacg
     6121 ccagagatcc cagatcatcc gttcggcttc ttccaactca tcttctttca atatcgtgtt
     6181 aagcgtaaca tagatgcggg cgccatacag atgcgcatac tcgcaaagct cgcgtatatc
     6241 ttccaaagag ttgccggcag cagcacgcgc accgaacttg ggtgcaccga tatagacggc
     6301 atcggcaccg tgattaatcg cttcaatccc gcaattgagg tctttagccg gagagagaag
     6361 ttctatagga cgggattttg tttgcatgct attatttctt atttcttgat tacaaatcac
     6421 ccaacttgct gatatcctcg atacggaacg gggtttcctg atagacataa tagttcagcc
     6481 agttggtgaa cagaagattg gcatgaccac gccagcggac caccggaccg agggccggat
     6541 tgttattacg gtaatagtta cggggaacgg caattggcaa tcccttgttc acgtcgcgca
     6601 tatactcgtc attcagcgtg taaggcgagt attcggaatg cccggtgata aaaaactcgc
     6661 gtcctccgcg cgccatcgcc atatagacac cagactcttc gctttcggac aagagcgtca
     6721 aatcgggaac tttcatcaca tcctcgcggc gtatctccgt atgccggctg tgcggcacat
     6781 agaactcgtc gtcgaagcct cggaagatcg gcacataggg ctcgcgcaac gtatggcgga
     6841 acacgccgaa catcttggct ggcagatcat atttggggac accataaaaa tggtacaacc
     6901 cggcttgcgc cgcccagcat atatataagg tagaagtcac atgcgtacgc gcccaatcga
     6961 atatctcggt cacttcctcc caatagttca cttcctcgaa aggcatctgc tctaccggag
     7021 cacctgtgat aatcatgccg tcgtaaaaat catcctgcat ctcgtcaaag tctttataga
     7081 attccttcat atgctcgatc ggcgtgttct tgggagtatg gccttttatc ttcataaagt
     7141 cgagctccac ttgcaagggg gtattgctca ggaggcgaac aaggtccgtc tccgtcgtga
     7201 tcttcagtgg catcaagttc agcacaacta cacgtagcgg acgaatgtcc tgctcagacg
     7261 cacgcaacga gtccatcaca aagatgtgct ctttcttcaa cagctcaaca gctggcaagt
     7321 tcttctgtag gtttaaaggc atcttctttc cttaattatt tatataaggc acaaagatag
     7381 tgagaaattg cctttcattg aaaataaatc gttgtttccc gcgtttgtag atttaataat
     7441 tagatggaat atgaagattc gtgcaatagc tacactacta tttatattat tttcgataag
     7501 tgctttcggg cagggacgtg ccaaaatcag cggttatatc cgcgacgcgg acggtaatcc
     7561 gctggacttg gtcaatatcc gggtcaagaa cacgttaaac gggacgatga gtaatgaaaa
     7621 aggccactac tcgctttcgg tcgctaccgg tgactcggtg acgcttatct attcatgcct
     7681 gggctacaac aaggccgaaa ggatcctacc tcaggtaacc aaagatatgc gtctcaacgt
     7741 gcagatgaac tatacatcac tcgaactggg agaagtcgta gctaccgcca tccgaaagca
     7801 gacaaccacc cttgaaaccc tgaatgccga ccgcgtcaaa ctactccccg accctgccgg
     7861 aggaagcatt gaaagtctgg tcgttacatt tgctggcgtt acttccaata acgaattaag
     7921 ttcgcaatac tccgtacgcg gcggcagcta tgacgaaaac atcgtatatg tgaacggact
     7981 ggaagtgttc cgtccgctgc tcatccgttc cggacaacag gaagggttga gttttatcaa
     8041 cccggacatg acggaagccg tcaatttctc cgccggagga ttcgaagccc gttatgggga
     8101 caagatgagt tccgtgctgg acatcaccta caaaaaaccg aaaggattcg aaggttcggc
     8161 ttccgccagc ctgctgggag ccaatgctta tgtgggcagt tcttccggca agttcacaca
     8221 ggtgaccggt ttccgttaca aaacaggacg atctcttttg aaaacaaccg atacggatgc
     8281 cgaatatgat cctaatttca ttgatttgca gacttatatg acataccagc ttgcccccaa
     8341 atgggagatc aactttctcg gaaacttagc cataaacaat tataagttca ttccccacac
     8401 ccgagagact tcttttggaa cggcaacaaa tgccaaaaaa tttaaagtat tcatgagtgg
     8461 ccaggaacgg gataagttcg aaacgttatt cggagcactc actttaaagc ataacctgaa
     8521 cgacaatacg gaactcggct tgcaagcatc cgcctttacc agtaaggaag aggaaggata
     8581 tgatattgcc ggtgattact ggctgggaga tgcagccgaa gaaggaggcg gagaaataca
     8641 gaaattatcc atcgcacgct ataacgagca cgctcgcaac cgtctgcact ccaatatcat
     8701 gaatgtcggg cattatggtg tcgctcgcat aaaaaacaat acgttgaaat ggggtgctac
     8761 cgtccagttg gagaaaatca acgacaagat cagcgaatgg gaaaaacgcg actccgccgg
     8821 atactcgtta ccgcaagggg gcgggaatgt caacgtgatc gcaaacctgt tctcggataa
     8881 caaactggaa agcacacgta tttccggcta tttgcaggat gtattcaagt ttcgtaccaa
     8941 acaaggactg ttcacgctgg ttggtggtgt acgcggcagc tattggagtt ataacaggga
     9001 atttatattc agcccgcgtg cttcaatagg tttcattccg aacttcgacc agaacctgac
     9061 atttcggctg gcttccggtc tgtattatca gtctccgttc tataaggaat tacgtacaac
     9121 tgtgcaggac gaacacggca acagtatcat acaactgaac aaaaacctga aatcacagcg
     9181 ttccatccat gtcattgcag gaggcgatta tacattccgg gcatccggca gaaatttcaa
     9241 agtcagtgcc gatatgtatt ataaaaaatt ggataacctg aacccctata cggtggataa
     9301 tgtcaaaatc cgatactacg gcgagaactg tgcgcaaggc catgcgatgg ggctcgatgt
     9361 caaattcttc ggcgaatttg ttccgggtac ggactcctgg atcagcttct ccctaatgaa
     9421 agcggagcaa agcatccgag ggagcgaata tgtaccgatg cctaacagcc aaggttataa
     9481 tgtctcgctc ttttttcagg attatttccc cggatacaaa cgtgtcaaac tgaatctgaa
     9541 aggcgtactg tccggcggcc ttcccgtcac agccccacgt acaggctacg aggacggcta
     9601 tttccgtact ccgacctaca aacgcgtgga cctcggtttc tcctaccagc ttgccggggg
     9661 aacggatgca atcatggatc gcggattctt ccgcaatctc aagaacattt ggctcggatt
     9721 ggatattttc aacttgttcg acataaagaa cactagttcc tattattgga ttaccaatat
     9781 agacaaccac cagtacgcaa tccctaatta cctgaccgga agacaattga atattcgact
     9841 tatcgttgat ttttaaccac atgatttcaa aaatatgctt tttaaacata tccggatcat
     9901 gctgataaat attaacgaat tatttctcta ttaataaaaa gagtgtacct ttgccaacat
     9961 agaacaaaaa gcaatattaa attactaaat tattattgac atggaactta cacatatcga
    10021 acatttgggt atcgcagtaa agagcatcga agcttgcctg ccgtattatg aagaagtttt
    10081 aggactaaaa tgctacaaca tcgaagaagt agcagaccag aaagtaaaaa ctgcattctt
    10141 taaagtaggc cagactaaga tcgagttgct ggagccgaca agtgaagaca gtacaatcgc
    10201 taaatttatc gaaaagaaag gtgaaggtat ccaccacatt gcatttgctg ttcccgacgt
    10261 acaggcagca ttggacgaag ccgaatcaaa aggtatcaag ctgatcgaca aagctcctcg
    10321 tggaggtgca gaaggcttga acattgcatt ccttcacccg aaatcgacat gcagcgttct
    10381 gaccgaactt tgcatgccgg gaaaataaga aacaattgac aattgagaat tgacaattat
    10441 ttgatgctat tcaattgtca attctcaatc gttaattgcc aattaaataa gttcatttct
    10501 aacaacaaat ctatagtaca atgagtaacc aacttgaaaa agtaaaggag cttatcgccc
    10561 ttcgcgaaac agctcgttta ggtggtggag aaaaaagaat cgaatctcag cacaaaaaag
    10621 gtaaatacac cgcacgcgaa cgtattgcca tgttgctgga tgagggaagt tttgaagaat
    10681 tcgatatgtt cgtacaacat cgttgtacaa acttcggtat tgaaaaaact aagtatttgg
    10741 gcgacggtat cgtaacaggt tacggaacga tcgacggacg tctggtatat atttatgctc
    10801 aggatttcac cgtgttcggc ggtgctttat ccgaagcatt ggccatgaag atctgtaaag
    10861 taatggatca ggccatgaag atgggtgctc ccgttatcgg tctgaacgac tcgggtggcg
    10921 cacgtatcca ggaaggtgtc aacgccttgg ccggttatgc agaaatcttc caacgtaata
    10981 tcttggcttc cggggttatt cctcagattt ccggtatctt cggtccatgt gccggcggtg
    11041 cggtttactc tcctgccctg acagacttca atatcatgac ccgcggaaca agttacatgt
    11101 tcctgactgg tccgaaagtt gtaaaaacag ttacaggcga agacgttaca caggaacaat
    11161 taggtggcgc aagcgtacat acgaccaaat ccggtgtggc ccacttcgca gtcgatacgg
    11221 aagaagacgg tttacagttg atccgcaaat tgatcagctt cctgccgcag aacaacctgg
    11281 aagaaactcc tctgatcgaa tgtaaagacc cgatcgaccg tctggatgac aacctgaacg
    11341 acatcatccc tgacaatcct aaccaggctt acgatatgta tgaagttatc ggaaccatca
    11401 tcgataacgg cgaatttctg gaagtacatg ccgactatgc caagaacatt atcgtcggtt
    11461 tcgcccgttt taacggccag actgtcggta tcgtagccaa ccagccgaaa gtaatggcag
    11521 gctgtctgga cagcaacgcc tcccgcaagg caggccgttt cgtccgtttc tgcgatgctt
    11581 tcaacattcc tttggttaca ttggttgacg taccgggatt cttaccgggt acaggccagg
    11641 aatacaacgg tgttatcctg cacggagcca aattgcttta cgcttacggc gaagccacag
    11701 tgcctaaagt aactgtaaca ttgcgtaaat cttacggtgg agcctattgt gtgatgagct
    11761 ccaaacatct gcgtggcgat atgaactacg catggccgac agccgaaatc gcagttatgg
    11821 gcccaagcgg cgctgtagaa gtgatctttg caaaagaagt ggctgcctcg gaagatccga
    11881 aagcttgcgc tgcagaaaaa gaagccgaat acaaaaaagc atttgcaaac ccatacaatg
    11941 cagctcaata tggctatatc gacgatgtta tcgaacctcg taacactcgt ttccgtatta
    12001 ttcgtgcttt acaacaattg cagaccaaga agttaagcaa tcctgccaag aaacatgaca
    12061 atctgcctct ataattctta aaacaggaaa tgaatatgat taataagaaa ataggggtat
    12121 tgctgctgtt cgcgttgctc gtttcattcg gggcaaaagc acagcgtgca acctccatgc
    12181 gaataaatga agtgctggtc atcaacgaag ataactttgt tgatgattac ggcaaacgcc
    12241 atgcctggat cgaattgttc aacaattcgg ccggttcggt caatatcgcc ggttgctact
    12301 tgactaatga caagagcaac ccgaaaaagt atccgattcc gaagggcgac gttctaacag
    12361 taattcctcc tcgccagcac actttgttct gggcagacgg agaaccggat cggggaacat
    12421 tccatgtcaa tttcacgctc gacccatcaa aagaaaatta cattgcgtta tacgatgcag
    12481 acggtagaac tctgatcgat gagatcgtta tccctgcttc acaaaaagca gatgtcagct
    12541 atggtagaac tttagacgga caaggagaat ggacagctct gacaaaagtt acacccagca
    12601 ccaataacgt aacattggat tctaacgaga aaatcgagaa ctttaaagaa aatgattctt
    12661 ggggtatcgg tatgaccctg actgccatgg cagttgtgtt ctccggatta ttcctgttgt
    12721 tcatcatctt taaacaaatc ggaaagctct cgatcgcggc cagcaaacgc aatgcacaga
    12781 aagcggccgg agcggctgtt attgcagaca atgcaggtca ggaatccggg gaaatctttg
    12841 cggctatcgg tgcggctcta tacgaaatga gcgacgacaa ccacgacatc gaacatacgg
    12901 ttctgacgat ccgcaaggtt caaagatctt attctccgtg gagttccaag atttacggtc
    12961 tgcgtgaagt tcccaaaaag taattatctc taaaaacaaa caagaatgaa aagttttaaa
    13021 tatactatta acggtaacgt atataaagta catatcagct cggtagtgga tgacatcgct
    13081 gaagtagaag taaacggtac tccctatcag gtaaaaatgg agaaaccggc aaaaaaacag
    13141 atggttacac tgaaacgccc ggctcaagct cctacaacgg caagtggcga accggttatt
    13201 tcccgtccgg cagcctcaac caccaagggc gctgtcaaat ctccgctgcc aggtgtaatc
    13261 ctgcaggtta actgtaaagt cggtgatact gtcaagagag gccagaatct acttgtcctc
    13321 gaagccatga agatggaaaa caacatcaac gccgaccgtg acggcaaaat cattgaaata
    13381 aaagtaaaca aaggggattc cgtactggaa ggtgctgacc tcgtcgtaat aggataatat
    13441 tatgttagga tcagtattat tacaggcagc aggtacggct catgaaagct ttctccagtt
    13501 cttgggagaa aacttggagt tgttcctcac ttatacagga gtctacaacg cgacaccggg
    13561 tcaccttatc atgatccttg tcggtctgtt gttcatcttc ctggctatta aatatgaatt
    13621 cgagcctatg ctccttatcc ctatcggatt cggtatcctg atcggtaaca ttccgttcaa
    13681 agatgcagga ttgcaggtgg gtatttacga acaaggttct gtgctgaaca tcctctacca
    13741 gggtgtaacc tccggatggt atccgccgtt gatcttcctc ggtatcgggg ccatgaccga
    13801 tttctccgca ttgatctcca atcctaaact gatgttgatc ggtgcagcgg ctcagttcgg
    13861 tattttcgga gcatatatca tcgctcttca aatgggattt gaaccgaacc aggccggtgc
    13921 aatcggtatc atcggtggtg ccgacggccc gacagcaatc ttcctttctt ccaagttagc
    13981 tccgaacttg atgggtgcta ttgcagtatc ggcatactct tatatggcgc tggttcctat
    14041 tatccagcct ccgttcatgc gcctgctgac gactcagaaa gaacgtctga tccgtatgaa
    14101 accgccgaga gccgtttctt ccacggaaaa gatcgtattc ccgatcgtag gcctgttgct
    14161 gacttgcttc ctagttcctt ccggtctgcc tctgttgggt atgctgttct tcggaaattt
    14221 gttgaaagaa agtggtgtaa cacgtcgttt ggctgaaaca gcccgtggtc cgctgattga
    14281 tacgatcacg atcctgttag gtattacggt aggtgcttct actcaagcaa ctcagttcct
    14341 gacattgaac tccatcaaga tcttcggttt gggagcgttg tcattcgtga tcgcaacttg
    14401 tgcaggtatc ctgttcgtga agttcttcaa cctgttcttg aaagaaggca ataagatcaa
    14461 tccgcttatc ggtaactccg gtgtgtctgc cgtgcccgac tctgcccgta tctctcagaa
    14521 cgtaggtctg gaatatgatc cgaccaacta cctgttgatg cacgccatgg gtccgaacgt
    14581 agcaggtgta atcggttctg ccgtagcagc cggtatcctg ttgggattct taggataatt
    14641 cacttattct acataaaaag gagctgaact ccaagtcatc tccaaatata aaaaattacc
    14701 caagtttacg gactttaacg tattcttggg taagtttgta tatgcgcaca acgattcatc
    14761 agaagtatat taatggctgt atcataaaaa actatttacg acacagcctc cctttttata
    14821 tccgacctta tcagatattt tgttcgacgg tcatcggatc tgtctctgga tttgcctcct
    14881 gttccaatgt tgtccccaaa aacaaccaaa tcattaacag gataatcgcg atcaccacac
    14941 caaagaccag cagtacattc gtattctttc gtctcatgtc tattcttcaa tattgatttg
    15001 aagattaaac aagacacccc cttttttggt ttaaccgttc cttacttttg ttctttattt
    15061 aactgagtaa atattttaga aagaatgttt ttttcttcac ttacaaatac aattggaaat
    15121 agacgatcca actatcatac catcataatt ggcaataacc cactatctat caacacaaaa
    15181 tagccatgac agttcgcaaa ataactgtca tggctactat cataccatca tacataaaat
    15241 tagtcaatca attatatatc aaccatctac ctcttccaca taataacaag tccccctcat
    15301 cgtccgctta ttcggcacgc tattccgctt caaaagcttg ccgaaattaa ggatcatcgt
    15361 ttttgtaatg ttaaaaccgg gttgtttctc cgcgatcata tccagtatct cggacgccag
    15421 aagcggcttt gcctcttcaa tatcctccgc gatcttgaaa taacgcagga acagttgctc
    15481 ttcagccggc tgctgctgga aatccctgtt gttttcagtg atcagcgcct cttcctccgg
    15541 agtaaaccaa aaacgttcac cacgcctcaa caattctttc gcttccgcat acaactgatc
    15601 ataatcgatc ggctgggcat aatcgatccg ccccttcacc tccacgcaaa tgaaacggcg
    15661 gctaccggtc ggatctgtca gcaaatcata attgttgctg gtcgcgataa acgtggcata
    15721 gcgacgcaag ttacggctcg cactctgata aggcaaacgg gtgttcacaa ccgctttttg
    15781 caggatatgc ttcaaaaaac tttgatgaga acttttcact gaatcaaatt catcgatatt
    15841 aatcaacgca taccggtgca aagccaactc cgccccacgg cgattgccga aatcgatact
    15901 gtccgtataa taaggacgca acactggtgg caacaaattc aagcaaaacg tggacttccc
    15961 acacccttgg ccaccgacca acagaggtgt cgtactattc ccgtgttccg aatccagttc
    16021 catccaatgt gccaccatgc ttaggaacca gcggtaaaac aaatctcccc ataccggatt
    16081 gtcacaaggg acacgcccgg ctaatgccct gatgcgttct tttccgtccc aagccggaag
    16141 attcccaaga aaatgatcga taggatgata tatcggaaca cgatcggagt tgacatatcg
    16201 gtcgatatcc ttgtcccata cattcaaccc ttcctgctgg gcttccaagc aaatggaatt
    16261 ccggactttc gtcgtataag gcttgtaaac gaactgtatc atcgaacggt ccaaatattc
    16321 cactccaccg ctcatctcat tcgtccggaa gaaataacgc cggttcataa actcgtccaa
    16381 ccgcaacact aacgacatgg atggcgggac ggaagagagc ggctccgccc ggtttgaaac
    16441 attctccaac gtatatgccg tacggaaagc catacggacg tctatcttat attttttcaa
    16501 agcttcatag cgcaatgtcc agcccaccgc ctcttcctcc ggtattccaa gccggcagca
    16561 agcctgcgcc aagtcgatga acagcagttg gatatcatct tccgggcttt ctgaaaaccg
    16621 acgcgtcatc tccatcagga tgacactgaa cagcgtggcg atctgcccgt tccgatccgc
    16681 tcccggagcc atcatctcca acggatcccg aaccgaagaa ggcacgatct tcaagtcacc
    16741 cccgtccggc atctgcaaag gttgctcgat ccggatcgcc accgcatccg gattgtaata
    16801 ggcgtccgga tccacactca tccggcaccc ccgcgacagg aacggttctt tcaacgatat
    16861 aatgctgccc aactgcggct ggtaatgccg caccgccagc tgataagccg cagcatgaaa
    16921 catacgggcc tgctcctctt ttttcggcag cgagccgtcg ggcagcacaa aaggaaccac
    16981 gatcttgacc gaacgcccgc tcagcccgac gaacgccagc aaggtctgcg gcagggcggc
    17041 agcttcacgg cggacggcct ccgcctcact ctggctttcc aagccgttca cttccaacaa
    17101 gacatacccg ttataacgcc tcaactgtat tccatcgcca ttcttcttga acgtcgagcc
    17161 aaaagccaga accggtagtt ttccggacaa atccgtggtt cgtgccaaaa acgccatatt
    17221 caattttcga cgaaccgaca gtatcgcttc cgcatctttg ccgtttttca gcaacccgac
    17281 aatatattcc atatcacgcg agtgcatccg caacacgcct tttttatgcc tgtaatatgt
    17341 gatttgcatt accaaggatt tctttcgaat ttgacaaatt tcatgctctt tctcacacag
    17401 ggagccatcc tgaaacagac acgacgcgcc ttcacccgat ggggagtaca ttttttcgga
    17461 tcttcgaagc cttcgctccc tgccgaaaga taaaaatcac ccaacccgtc caactccacg
    17521 gaatagccgt ctttcaacaa ttcaagaatc atccctccga tctcgcaaac cgaagcgaac
    17581 acatcacctc ggctcaacga gcaacgatcg gcaaccaaat cagccagctt tttcgttgaa
    17641 acccgcccgc acgtaaccgg aacaccataa tagcgtactt tatcttccgc tcccgtcttg
    17701 tccagttttt gccggactac atagtaatgt gccataaata acagtatttt taatattaaa
    17761 caaccagata ttcttctcaa gacgcccatt ttaacacttt tgacaccccc atctgaacgg
    17821 tatcaacacc cgggtctcac cccttccgac acccggatga cgggcttctt ttcttattac
    17881 aaatatacaa ataaaacatc tataatacaa atatttacag cactttattc aattatatct
    17941 acacttattt ttccccagca cgaagacaga agcatgtgat atacgacatg atagtatgat
    18001 agtatgaaat gatagttgaa aatagatact atcatatttt tataaactaa tatacagata
    18061 tttatatgta aatatgatag tatgatagtt ggatttaaaa aaaatcgtat gtatataata
    18121 ggtggatgtt tacagcagct tatttatatt gcttgcagga ggaagactta catggatggc
    18181 aaccctaaat aacacatcgt cccgtttcca tgtttgacat tacagctatc aaacacaaga
    18241 aacaggacga ttttgcatat ctaagttctt ttccgattga ccggacttac ataaaaattt
    18301 cgacaaacgt gccattccga catagcacac aactacatca tcgagctaaa agcaccttat
    18361 tttttgcaac cgtcgcctgg aactctttca ggtagaacgg ttcgaaatag gcggtgtctt
    18421 caaacttgcc ggcggcaaaa gcttgttccg agagcggaat catgtttacg gcaagaggat
    18481 ggatgtcctc gataaagatg gcgttcggag aagtgatgac cgatttgcat ttggaaacac
    18541 cgttgccaaa gaaacaaact ttcccttttt ccagataaga agcatacgta ccggcttcca
    18601 caatatcggc cttcgtctcg cggacaggct ttaaggaagc atcgtagata gcggcataaa
    18661 cctccatacg ccgggcatcc aacatagcac aataaaggca atcatcagta atagagacga
    18721 tttgcgaatc gcccttactg ttgacagtag cagccatgat gtccaacgta tgaatgccga
    18781 tcagaggaat accgaaacca aagcaaagac ctttagcgac agacactccg atacggagtc
    18841 cggtataaga accaggaccg ctactgaccg ctacggcatc caaggctttc ttccccttct
    18901 ttttcaatac ggaaagagct tcttcaacaa atacgcctaa taaggctgca tgcgaagggc
    18961 cgtcgaacga ggccttcgca aaaaggactt caccatccat agacaacgct acagagcata
    19021 cagaagtcga tgtttcgata tttaatatac aagacatttt aattgacaat tgacaattga
    19081 caattgacaa ttaaaatatg tgtcaaaagc caatcgattg ataatggatg caaaagtata
    19141 aaacataact gtaatctcat gatcaaaacc gattttatta aggctgacac ggatggtttc
    19201 ggctttttct caattatatt gtcaatcgtc aattgtcaat tatcaattga ttagctatct
    19261 ttgcacaaat ttttagaaca atgatacaat caatgactgg attcggtaag gttacagccg
    19321 aacttccttc taaaaaagta accgtagaaa taaaagctct gaacagcaag caactggatt
    19381 tgtcgacccg cattccttcc atctacaaag aaaaagaaat gcaaatacgc agtttgttac
    19441 tccagtcgct tgaacgtgga aaagtcgaat ttaatatatt tgtcgaatat atcggtaaag
    19501 acacgcccac acagatcaac ttggctgcgg tagaaaacta ttacaatcaa atcaaagata
    19561 ttgccgaccg cctgaacatc ggacttcccg ccgactggtt ccagaccctg ctccgcatgc
    19621 cggacgtgat caagacagag gcccaggaag taaacgaaga ggaatggaat gtggttgaga
    19681 aagcgatcaa agaggccata gggcaccttt gcgatttccg tattcaggaa ggcgccatgt
    19741 tacaaaagtt gttcgaacag aaaattgcca atatctcccg cctgctttca gaagtagaac
    19801 cgtatgaaaa ggagcggatc gaaaaaatca aagcccgtat catggacaat ctcgaaaaga
    19861 ttgccggaca ggactacgac aagaaccggt tcgaacagga gatgatctat tatatcgaaa
    19921 aactggatgt aaacgaggaa aagaaccgcc tggacaacca cctgaaatat tacatcagca
    19981 cgatggagag cggacacgga caaggtaaga aactcggttt catcgcccag gaaatgggac
    20041 gtgaaatcaa cacccttggt tcgaaaagca accatgccga gatgcaaaaa cttgtcgtcc
    20101 agatgaaaga cgaactggaa caaatcaaag aacaagtatt aaacgtatta taaaaacgat
    20161 atatggctgg caaactgatc atattctccg cgccgtccgg ttcgggcaaa tccactatca
    20221 tcaatttcct gctgaagcag aatctgaacc tgcatttttc catctcggct accagccggg
    20281 ccccacgtgg tacggaaaag gacggagtgg aatattattt ccttacaccg gatgaattcc
    20341 gtgcccgtat agcagcagga gatttcctgg aatacgaaga ggtctatacc gacaaatatt
    20401 acggcacgct gaaaagcgag gtggaacgaa ggctgatgag tggcgataac gttatattcg
    20461 atgtcgatgt cgtaggaggt tgcaacatca agaagtttta tggcgaccgt gctctttcgg
    20521 tctttatcca gcccccctcg atcgaagatt tgcggagtcg tctggaagga cgcggtacgg
    20581 atgctccgga agtaatcgaa agccgcattg ccaaagccga atttgaactg ggttttgccg
    20641 acaaatttga cgtaatcgtg gtgaatgaca agctggaagt cgcacaaaaa gaagcactaa
    20701 aagtgataaa agagttcctt aaaaaagcat gaacggcaag aagttatcca agaaatggct
    20761 atatacattc attggtatag catttgtcgc tcttgccact tgtacagccg ccctatatta
    20821 taaggagtat atcatagcga ccggtaccgg attggtattc ggtgcacaag tcataaatat
    20881 catcaagtgg aaacgggact gaaagaaaat acggtcagca aacgtaaaac cggcatttat
    20941 tccggttcat tcaatccggt tcatatcggc catctggcat tagccaactg gttgtgtgaa
    21001 tttacggagt tggacgagct atggtttctg atcacccccc ataacccgct aaaagagaag
    21061 gaagaactga tggatgaccg gcttcgctat gaactggtaa aaaaatccat cgctggttac
    21121 cctaagttcc acgccagtga cttcgagttt tcccttcctc aacccactta taccatcaac
    21181 acactccgga cattggaagc aagttatccg gaccgtgaat tctatttcat catgggtgcg
    21241 gacaattgga aatatattac ccggtgggta gaatacgaag ccatcatttc caattatccg
    21301 atcttcatct atccgcgcaa aggattcgat gttgaaattc cggcacaata tcctcacata
    21361 aaaaaagtag acgccccttt ggtcgaaata tcctcaacct ttatacgcga agctttcaag
    21421 accggaaaag atgtccgctt cttcctgccc gaagccatac gtaatctgcc ttttccatta
    21481 caaaacaata ccttttaaga acataaagcg taaagtcgca tacgttttta ggcaataagt
    21541 aagaaaagtt ttgtattttt gcgccgtatt atacaaaata atagcgtaat gaatctatta
    21601 gaactgagtg aacaggaaat cataagacgt aacagcatgg agcagttacg tcagatgggg
    21661 atagaacctt atcccgcagc tgagtatgta acgaatgcat tttccaaaga gataaaagag
    21721 aattttaaag acgatgcaga gccccgcccc gtaagtattg ccggtcgcat catgagccgc
    21781 cgcatcatgg gaaaggcttc cttcatggaa ttgcaggatt cagaaggcag aatacaggtt
    21841 tatatctctc gtgacgacat ttgcccggaa gaaaataaag atctgtataa cattgttttc
    21901 aagaaattgc tcgatatcgg cgactttgtc ggaatcaaag gtttcgtatt ccgtacacag
    21961 atgggcgaaa tttccgtcca tgcacaagag ataacggtat tatccaaatc actcaagccg
    22021 ctaccggtcg tcaaatacaa agacggtgta gcatacgatg gattcaacga tccggaattg
    22081 cgttatcgcc aacgctatgt tgacctggtg gtcaatgatg gcgtaaagga tattttcatg
    22141 aaacgtgcgg cagttatcaa gaccatgcgt accgccctgg acgaagctgg atatacggaa
    22201 gtggaaactc cgatcctgca atccatcccc ggaggggcaa gcgcacgtcc gttcattacg
    22261 caccataact cgctggatat cgacctctat ctgcgtattg ctaccgaact gtatctgaaa
    22321 cgattgatcg tcggaggttt cgaaggtgtc tacgaaatcg gtaaaaactt ccgtaacgaa
    22381 ggtatggatc gcacccacaa tccggaattt acctgtatgg aactttatgt ccaatataag
    22441 gactacaact ggatgatgag cttcaccgaa cagctgttgg aacgtatctg tatcgccgtc
    22501 aacggtacat gtgaaagtgt agtcgacggc aagaccatca actttaaagc tccttaccgc
    22561 cgtctgccga ttctggatgc catcaaggaa aagacaggtt acgacctgaa tggcaagagc
    22621 gaagacgaga tacgcacgat ttgcaaggat ttgaaccttg aaatcgatga aacaatgggt
    22681 aaaggcaagc tgatcgatga aatcttcggt gaattctgcg aaggcacgtt tatccagccg
    22741 actttcatta tcgactaccc ggtcgagatg agtccgctaa ccaagatgca ccggagcaaa
    22801 cctggattga ccgaacgttt cgaattgatg atcaacggta aagaagtggc aaatgcctat
    22861 agtgagctga acgatccgat cgatcaggaa gagcgcttca aagagcaatt gcgcctgagc
    22921 gaaaaagggg atgacgaagc gatgttcatc gaccaggact ttttgcgtgc actgcaattc
    22981 ggtatgcctc cgacgtctgg tatcggtatc ggcatcgacc gtctggtgat gttgatgact
    23041 ggccaaacga ctattcaaga agtgttgctc ttcccgcaga tgcgcccgga aaagacagtt
    23101 aagaaagaca ccgcagacaa atatgtcgca ctgggtatcg atgaagcatg ggttcctgct
    23161 ttacataaag ccggatatct cacaaccgac acgttggtag atgctaatcc caacaagctg
    23221 agacaggaac tctgcgaaat gaataagaaa tacaaactgg aattgcaaaa ccccactgcc
    23281 gaagaagtag aggcatggat tgcaggcgca gccaaataag agtaatacta tgaagttgcc
    23341 cggaaaaatt gcaataatgg gaggtggtag ctgggctacc gccttggcca agattgtact
    23401 ttctacacaa gatagtatta actggtatat gcgtcggcca gaccaagtag aagagtttct
    23461 gttgttggga cataacccca gctatctttc cgccgtcaaa tttgatactg acaaaatcaa
    23521 attctacacg gatatcaaca aagtaatcaa agattcggac actttgattt tcgccacccc
    23581 ttctcctttt ttgaaacaac atttgatgaa ggtgacgacc tccatgcaag acaaattcat
    23641 catttcggcc atcaaaggaa tcgttccgga cgaaaacatg ctcgtagccg attattttgc
    23701 cgaatactac aatgtcccga ttgacaatat cgctgtcatc ggcggtccgt gccatgccga
    23761 agagatcgct ctcgaacggt tgtcctatat cacgctggct tgccctaata tcgagaatgc
    23821 aagagctttc tcctccgtat ttaagaacca gtatctgaac aactcctgtt gcaaggatgt
    23881 tacaggtatt gaatatgctt ccgtattgaa aaacgtatat gccatcgtcg caggtatctg
    23941 ccacggtatg aagtacggag ataattttct ggcagttttc atctgcaacg cgatcgaaga
    24001 gatgcgtaac ttcctcaacg ccgtacatgg cctggaacgg gatgtgacag attcggtata
    24061 tctcggtgat cttctggtaa ccgcatattc tcgcttcagc cggaaccgta cgttcgggac
    24121 catgatcggg aaaggttatt ccgtcaaaat agcccagctc gaaatggaga tgatcgccga
    24181 aggatactac gggacaaaat gtattcggga gataaacgaa aaatataaag taaacatgcc
    24241 gatcttggat actttatata gtattctata cgaaaagaaa tcgccgacta ccgcgatacg
    24301 gcagttgact gaaacattta aataataatg taaatatgaa gaacatcagt cttaacattg
    24361 acaaagcgct gggtaccgta acgaaagaac aggtatatgc tcaggctgca aaggcccacg
    24421 aatgtaatgc cactttacaa aatggtaatg gtgcaggtaa cgacttttta ggttggttgc
    24481 acctcccctc ttctattaca gatgctgaac tgacagacat cgaaaataca gctaacgtac
    24541 ttcgttccaa atgtgaagtt gttgtcgcca tcggtatcgg cggcagctat ttaggaacaa
    24601 aagcagtggt agaagcatta aacaatagct tcgactgg
//
