LOCUS       c00008_gnlPro..        14916 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OKGLHIPJ_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:29:31
            Original ID  :: gnl|Prokka|OKGLHIPJ_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14916
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14916
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1476:4916]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1477..4916
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14916
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14916
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(264..1217)
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPASGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1477..2151
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_2"
                     /sec_met_domain="SucD_FumR (E-value: 7e-67, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2190..4133
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.7e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4161..4916
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_4"
                     /sec_met_domain="Fer2_3 (E-value: 7e-26, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.1e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.2e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             5107..5265
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5238..6185)
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MCKRFGADMVYTEFVSADALIRSVNKTQQKLNVADEERPVAIQIY
                     GRDVPTMVEAAQICEAAHPDILDINFGCPVKRVAGKGAGAGMLRNIPLMLDITREVVKA
                     VNIPVTVKTRLGWDADNRIIVDLAEQLQDCGIAALSIHGRTRAQMYTGEADWTLIGEVK
                     NNPRIQIPIIGNGDVTSAEICKQRFEQYGVDAVMIGRGSIGRPWIFREVRHYLDTGETL
                     PAESFSWYLNILKKQVEQSVERLDERRGILHIRRHLAATPLFKGIADFKQTRVAMLRAE
                     TVEALFDILDSIPDKFHTGYGFQSDSQVSESIDC"
     CDS             6674..7909
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_7"
                     /sec_met_domain="Peptidase_U32 (E-value: 9.1e-69, bitscore:
                     223.7, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNNFTTDDLRK
                     IVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAMNYANSIGQ
                     EVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITGPKGELIRI
                     EMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIELDIENQYIM
                     SPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNGTFDEKKVA
                     AWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDKIGVAEFEM
                     ESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEKIRPSDRLY
                     KMEKVQLEKVFE"
     CDS             7909..8316
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_8"
                     /sec_met_domain="HBT (E-value: 1.4e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 2.1e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             8349..9428
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MINGVGDILARHLLQALGEAEAVFTEKQQLLGRIPGIGSNIAAEI
                     KRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYFKGNTNLDATRII
                     SIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRNALYNRLPTVAVL
                     AHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIVAGISDCTIVVES
                     AEKGGSLVTADIAFSYGRDVYSFPGRIGDSHSKGCNNLIRQNKAGLITSADDLLSALCW
                     DIQAGATSVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVLEIPVHQLSMLLF
                     ELEINGKVKALPGNLYKLS"
     CDS             complement(9679..10569)
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYFRY
                     APDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDETID
                     RTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDVPL
                     EVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPWKQ
                     VMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPDVI
                     ETDYPYLFQGLDLTK"
     CDS             11177..11539
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             11560..13296
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLPGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPV
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNPVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKVVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPSGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             13330..14883
                     /locus_tag="ctg8_13"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLRKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVADLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
ORIGIN
        1 cctcctgaaa aatattaccg agttcaaaga gttagactct gccaagacga cttttatctc
       61 tactatctcc catgaatctt atagatccgg gtgtcggggg cggatacatg ggggtgttgg
      121 gtaagtttta ttacgtgttt ttcattgatt tgtagctgta tttacataaa agagccttgt
      181 ctttgatgat ataggagaac aagccctttt tccttttctt gtttaccttg ccctgcaaat
      241 tgtcagtttg ttttagtaga aattcaatca cgttcgaaat cggacagcac ttctgccgta
      301 gtagcgttga tgttcttgtc caatacataa atgcggtaag acaggctcag ttctttaccg
      361 ggttccaagg tgaatgcctt ctgcttggtc ggtgagaaat tccacatgac gtcaccggca
      421 ggcttgttga cagttttgtc ccatacgcgt aaaggctcag gatagttcag gttggaaggg
      481 gaggcaacga ttaggataca ggccttttcg tttccggctt tcccttggta gtagcaccaa
      541 cgggctctcg aaccgtcagc ttcgtcgcgg gaaaggcctt ccgaggtgag catttcggct
      601 gtctgatcgt tccagtcttc gcgcgtacgg atgcatatgc cgccataacg gtaagcttcc
      661 atggtgatcg ggctggggct ggcgaggcgg atagtggtat gatagtcgat gtaataacct
      721 ggtaaggatg ttgtcccgat gttgatctcc aggcgttcgt tcattgctac tttttctgcg
      781 ggagaatcgg ggtagaccac atggtccagt gtcgcaacaa aaccgttgtc ggatacgtgt
      841 tcgaagttgc ggaagcgaac tgttccttgt tttttgtgga gattccagaa gtcgatctcg
      901 tttccttcga acgtggtttt cgtccaggca taccacaaac cgaaatgatg gtaatggtcg
      961 gcgggagaac aattggtcat cacttcgcct cccaatgtct tcaaaggatg gatgaaaccg
     1021 ctgcgtttat agaccgagtc aacgccagag gctgggtaaa ctgtggtata gttgtaagag
     1081 aacaacagtt tatctcctat cttatagtct aaggttttcc ccgtgtcgac gacggaacag
     1141 gatgtttcgg aaggctgaca agagcctaag aacagagaaa tcaaaaaaac accaatagaa
     1201 aaaatagcag ttttcataat atgacaatta aataataatc agttatccgg caagaccttg
     1261 cctgtatcgg ctacaaaaaa acgaaatttt ttcgtttcgc acaatccgtt tgtgatatct
     1321 gatgcaaata aaaccagcca gcaagcagcg ttctaattga tgaaatattt ctttaatcgt
     1381 ttgcgtgata tggggattta gcataccttt gcacgataat aaccatagat tggaggaaat
     1441 ttctaaatac aattaaataa cttaaattat tatcttatgt ggttacttaa ttcttctatc
     1501 gggaagaagc tgataatgag tatatcaggt ctttttctca ttctgttctt ggtgttccac
     1561 ttatgtatga acattgcggc agtattttct ggtgaagcgt ataacgtgat ttgcggtttg
     1621 ctgggttcta actggtatgc tttgctcggt acattggtgt tggctgcagg tgtagtcgtg
     1681 cacttcgtgt atgctattat cttgactctg cagaatcgta aggctcgcgg taacgaccgt
     1741 tatgccatca acgctcgtcc gaaaggtgtt gaatgggctt ctcagaacat gtttgttttg
     1801 ggtgtgatcg ttatcctgtt catggttctg cactttactc agttctggta caacatgatg
     1861 tttgccgaac tggcaggtat tcatggtgac attcatccgc aggatggtgc agcgtttatc
     1921 aatttctact tccagggcaa tgtcgtgaat acggtgttgt atctgatctg gttcgttgct
     1981 ctgtggtttc acctgactca cggtttctgg tctgcgattc acacaattgg ctggaacaat
     2041 accgtttggt taagccgttg ggaatgtatc tctaaatggg ttgccactat tatttgtggc
     2101 ttattcgctg ttatcacagt tatcttctac ctgaacggtg taggtgctta atttcggata
     2161 ttattttttc aatttgaaaa taaaacatta tgactcaaat agattctaaa attcctcaag
     2221 gcccgttggc tgagaagtgg acaaattata aaaatcacca gaaattggtg aatcccgcaa
     2281 acaaacgtcg tttggacata attgtagtag gtactggtct ggcgggtgct tctgctgctg
     2341 cctctctggc tgaaatggga ttcaatgtat tgaatttctg tattcaggac tctccccgtc
     2401 gtgcacactc tatcgctgca cagggcggta tcaatgcggc aaagaattat cagaatgatg
     2461 gtgactcggt ttatcgtctg ttctacgata caatcaaagg tggtgactac cgtgcccgcg
     2521 aagcaaacgt ctatcgtctg gctgaagtgt caaactctat tatcgaccag tgcgtagcac
     2581 agggtgtacc attcgctcgc gaatatggtg gtctgttgga taaccgttca ttcggtggtg
     2641 ctcaggtatc ccgtacgttc tatgcccgtg gtcagaccgg acagcagctg ctgttgggtg
     2701 cttactctgc attgagccgt cagattggtt tgggaaaggt gaagatgtac acacgccatg
     2761 aaatgctgga tgttgtgaag gttgacggac gtgctcgcgg tattattgcc cgtaatttga
     2821 ttaccggtaa gatcgaacgt tttgccgctc acgcagtcgt tgttgcgaca ggtggttatg
     2881 taaatacatt cttcttgtct actaacgcga tggcgtctaa cggttctgct gcatggcagt
     2941 gctacaagaa aggggcttac tttgctaatc cttgtatggt gcagatccac ccgacttgtg
     3001 tgccggtgaa aggtgacttc cagtctaaac tgactttgat gtctgaatca ctgcgtaacg
     3061 atggtcgcat ctgggttccg aagaagctgg aagatgcgaa ggcattgcag gccggaacaa
     3121 aaaagggaaa ggatattcct gaagcagatc gcgactacta tctggaacgt cgttatccgg
     3181 cattcggtaa cttggttcct cgtgatgtgg cttcacgtgc cgctaaagaa cgttgtgatg
     3241 ccggtttcgg tgtaaatagc acgggcttgg ctgtattcct ggatttctcc gacgctatca
     3301 accgtctggg taaggaagtg gttaaacaga aatatggtaa cctgttcgat atgtacgaag
     3361 agatcacgaa cgatgatccg tacgaaactc cgatgatgat ttatcctgca ttgcactact
     3421 caatgggtgg tttgtgggta gactatgaat tgatgacttc tattccgggg ctgttcgcaa
     3481 ttggtgaagc caacttctct gaccatggcg ctaaccgtct gggtgcttct gctttgatgc
     3541 agggattggc tgatggttac tttgtattgc cttacacgat ccagaactat ctgtctgacc
     3601 agatccaggt tccgcgcttt agcactgacc tgcctgaatt tgtggaagca gaaaaggcta
     3661 ttaacgcccg tatcgcgaag ttgatgaacg tgaagggtaa agaaactgtc gattctatcc
     3721 accgtaagct gggacatatc atgtgggaac acgtcggtat ggcacgcgac gcggaaggct
     3781 tgaaagaagc tatccaaatg ttgaaagacc tgaagaagga attctggagc aatgtattca
     3841 ttccgggtga agcgaacagc ttgaacgtgg aattggacaa ggcattgcgt ttggctgact
     3901 ttatcgaaat cggtgcattg atggcacacg atgcgttaga ccgcgcagaa tcttgtggtg
     3961 gccacttccg tacggaacat cagaccgaag aaggcgaagc tatgcgtcat gacgataagt
     4021 tcatgtacgt ctcttgttgg gaataccagg gtgaagacaa agacccggtt atgctgaagg
     4081 aagatttgaa ctatcagttc gttgttcctc aaacacgtaa ctacaagaag taataatcat
     4141 caatcacaaa aattagaatc atggataaag atataaaggt aacacttaaa gtttggcgtc
     4201 agaaaggtcc gaaagataaa ggacagtttg agacttacca aatcgacaaa atcaatcaga
     4261 gtgtttcttt cttggaaatg ttagacattt tgaatgaacg tttggttagc gaaggtaaag
     4321 aacctatcgt attcgaccac gactgccgtg aaggtatctg cggtatgtgt tcattgtatg
     4381 taaacggaca tccgcacgga ccggcaacag gtgcaacaac ctgtcagctc tatatgcgcc
     4441 gtttcaatga tggtgagacg attacgatcg agccgtggcg ttctgccggt ttcccggtaa
     4501 tccgcgactt gatggtagac cgttatgctt atgataagat tatccaggca ggtggtttcg
     4561 tttctgtaaa cacaggtggg gttcctgatg ctaatgcaat tcctatttct aaggctgatg
     4621 cggatttggc tatggatgct gctgcttgta tcggctgcgg tgcttgtgct gctgcttgta
     4681 agaacggttc agctatgctg ttcgtctctg caaaggttag ccagctggct cttttgcctc
     4741 agggtaaggt ggaagctgct cgtcgtgcaa aagcaatggt tgctaagatg gatgaactgg
     4801 gctttggtaa ctgtacgaac actcgcgctt gcgaaatgga atgtccgaag aacatctccg
     4861 ttagcaacat cgctcgcttg aaccgcgagt tcatctctgc taagttacaa gactaataca
     4921 ttatatatat gtatatggaa aagcccgtcg tcaatggcaa cgggctttct ttatgttcgt
     4981 tcaaacccac aaaaaagccg cactccctat aataaaagtg gatgcggctt ttttgttgct
     5041 ttccagtgaa acagtctctc gattccctct ctgcaaagac tttgttaacc ttagatctaa
     5101 aatactatga aaaaaactca ctgcaaatat aaagtatatt tactgaatac gcaagagttt
     5161 gtaattacat tttattgcaa atttgctact ttttgtttta aaattgacac tgtgtgcgga
     5221 ttcacactgt tattatatca acaatcgatc gattctgaca cttgagagtc gctttgaaat
     5281 ccgtatcctg tatgaaattt gtcggggatg gaatccagaa tgtcgaataa tgcttccact
     5341 gtttccgcac gtagcatggc gacgcgtgtc tgcttgaagt ctgcaatacc tttaaacagc
     5401 ggagttgcag ccaaatggcg gcgaatgtgg agaattcccc ggcgctcatc caaacgttcc
     5461 acgctttgtt ccacctgctt tttcagtatg ttcagatacc atgaaaaaga ttcggcaggc
     5521 aatgtctcgc ctgtatccag ataatgcctc acttctctga aaatccaggg gcggcctatg
     5581 ctgccccggc caatcataac ggcatccacg ccatattgtt cgaaacgttg tttgcagatt
     5641 tcggcggaag tcacatcgcc attgccgatg atgggaattt gtatgcgggg attgtttttt
     5701 acttcaccga tcagtgtcca gtctgcctct cctgtataca tctgtgcccg ggtacgtccg
     5761 tggatggaaa gggctgcgat accgcaatcc tgtagctgtt cggccaagtc tacgatgatc
     5821 cggttgtcgg catcccagcc caagcgggtt tttacggtga cagggatgtt caccgctttg
     5881 acgacttcac gggtgatgtc cagcatcagt ggaatattgc gcagcatgcc ggcgcctgct
     5941 cctttgcctg ccactcgttt gacagggcaa ccgaaattga tatcgagaat gtccggatga
     6001 gcggcttcgc aaatttgcgc ggcttcgacc attgtcggaa catcacggcc atatatttgt
     6061 atggcgaccg gacgttcttc atccgccaca ttcagctttt gctgtgtttt atttacactg
     6121 cggatcaggg cgtctgctga aacgaattcg gtataaacca tatcggcacc aaaacgtttg
     6181 cacatcaacc ggaaagaaat atctgtaacg tcttccatcg gagctaagaa gacggggcgt
     6241 tcgcctaaat ctattgtacc tattttcata tttatattat caatgacggg gacaaaggta
     6301 ctgatttcct gctaaaaaca gggataaaag gatatctact aaaaagtgta gtaattgatc
     6361 aatagaaagt acaaatgtca tactgtcaat gatatagata aaatgataag ctgaaatcat
     6421 gatagttgca tgatagtagt atgatagtta aaaatagaaa ctatcatgtc ttaaggtatt
     6481 gaataacaga ttctaaagga caacaatgac agtatgatgg ttgttttgca aatctttata
     6541 gaaaatggta tttgatcacg attttgatgc tctgagaaac ggatacccat gcaattcttc
     6601 tcggatatta ttcctacctt tgcgaacgaa ccagtaaatg tataagaact tgaacgagaa
     6661 agattttgaa ataatggcgc ctgtcggttc gtacgaatca ctgatggcgg ctatccaagg
     6721 gggagccgat tctatctatt tcggtatcga aggattgaat atgcgttcgc gctcttccaa
     6781 taactttacg acagacgatt tgcgcaagat cgttgcgctt tgtcgtgagc acggtattaa
     6841 gagctatttg accgtcaata cggttattta tggggaagac ctgcctctga tgcgcgagat
     6901 tatcgatgcg gcgaaggagg cggaagtttc agcgatcatt gcggccgatg tggcagctat
     6961 gaactatgcc aacagcatcg gacaggaggt gcatctttcc acacagctca acatttccaa
     7021 tgcggaagca ctgaaattct atgcccgttt tgccgatgtt gtcgtcttgg cgcgtgagct
     7081 gaatttgaaa caggtgcatg aaatctatcg gcagatcgtc gaccagcaga ttacgggacc
     7141 gaaaggagaa ctgatccgta tcgaaatgtt tgcccacgga gctctctgta tggccgtttc
     7201 cggtaaatgt tacctgagcc tgcacgaaat gaacgcttcc gccaaccggg gagcttgcat
     7261 gcagatttgt cggcgtgctt attcggtaaa agataaagac agcaatatcg aactggatat
     7321 cgaaaaccag tatattatgt cgcctaaaga ccttaagaca attcatttca tgaataagat
     7381 gatggatgca ggtgtacggg tattcaagat cgaaggacgt gcccgcggtc ccgaatatgt
     7441 ccgcctggtg accgaatgct ataaggaagc tgtgcgtgct tattgcaatg gcacgttcga
     7501 tgaaaagaaa gttgccgctt gggacgaacg cctgcgcagt gtgttcaacc gaggattctg
     7561 ggacggctat tatttggggc aacggttggg tgagtggagt agcaaatatg gctccggcgc
     7621 gactaagaag aaagtgtatg ttgccaaagg aatcaaatat ttcgacaaga tcggcgtggc
     7681 ggagttcgaa atggaatccg gtaacctgaa agtgggtgat gagatcctga ttaccggacc
     7741 gacaacgggt gcggttatgc agacgataga agaaatccgt gtggacttga agccggtgga
     7801 cgagaccgtt aaaggtgaac ggttctctct caaggtgaac gagaagattc ggccgtctga
     7861 ccgattgtat aaaatggaaa aggttcaact tgaaaaggta tttgaataat gaaagagtat
     7921 atttttaaac tgacagacaa ggtccgtgac tacgaatgcg acctgcaagg agtggtcaac
     7981 aactccaatt atcagcatta tatggaacat actcggcatg aattcttgga gtcgcttggc
     8041 gagaacttcg gaaagatgca cgaaaaaggg gttgacggat ttgtatcgcg ggtagaaatc
     8101 cagtataaga cctcgctcaa gagcggcgac agctatatct cttgcctcaa tgtctataaa
     8161 aaaggagtca agctcgtatt cgagcaggat atatataggg cttctgacaa tgcattggcg
     8221 acgaaaggaa tcgtcgagtc ggttatcgtt gagaacggaa agttgacacg cggtgaatat
     8281 ttcgacgaaa tgctaaaaag aatagaacat acatgactga caaacggatt taccaaatcg
     8341 gccttactat gataaacggc gtgggagata tcctggcgcg tcatctcctg caggctttgg
     8401 gagaagcaga ggctgtgttt actgaaaagc aacagttgtt aggaaggatc cctggtatcg
     8461 gcagcaatat tgctgccgaa atcaaacgcc cggaaatctt gcaacgggcg gaaaaagagt
     8521 tggcttttat cgagaaaaac aatatttcct gttattatct gactgataca gattatccgg
     8581 tgcgcttgag agaatgtccg gatgccccta tacttttcta ttttaaggga aatactaacc
     8641 ttgatgcgac ccgtatcatc agtattgtgg gtactcgcaa cgcgaccgaa tatggtcggg
     8701 agcttaccga atcccttata aaagacttgg caaaagtgat cccggacttg ttggtcgtga
     8761 gtggattggc ttacggcatc gatatctgtg cccaccggaa cgctttgtac aaccgacttc
     8821 cgactgttgc tgtgctggcg catggcttgg atcgtatcta tccttcctgc catcggaata
     8881 cggctgtcga aatgctggaa tcgggcggtc tgttgaccga ttttcccagc ggtacagaac
     8941 cagaccgtcc aaatttcctc cggaggaacc ggattgtcgc cggaatctcg gattgtacga
     9001 tcgtggttga atcggcagaa aaaggaggct ctttggtaac tgccgatatt gcattctctt
     9061 atggccggga tgtctatagc tttccagggc gcatcggtga cagccattcc aaaggatgca
     9121 acaatttgat ccgacaaaat aaagccggcc tgatcacttc tgcggacgat ctgctctccg
     9181 ctctttgttg ggatatccaa gctggggcta cttccgttca aacggagttg tttttcgccg
     9241 aggcggaaac attcacctcg gaacaaaatc cggttttagc cattatgcga acgcggaatg
     9301 agatccatat caacgagctt gcctcagtgt tggagatacc ggtacatcaa ctctctatgc
     9361 tattgttcga actggaaata aacgggaagg taaaagcgtt gccgggaaat ctctataagc
     9421 tgtcctgacc ggctttttcg tatacgattt gtatgtggga gaagaaacgg aacctctata
     9481 aacaattaaa ggctgtctca cgacaacccc taaccaactt tgttaacctt aaatctaata
     9541 ctattatgaa aaaaccacat tgcaaagata cactcgtcaa gagcgtttgt caagcatttt
     9601 gtcgctaata cttgttaatc agatgagcat aaatagcaaa aagattttaa tcggctataa
     9661 agagtccttt aaactgcgtt attttgttaa atcgagtcct tgaaacaggt acggatagtc
     9721 cgtttcgatc acgtcgggac gagtgctgat ctctgaccgg taaccggcgg ttttctctgt
     9781 ttccgttttc gcgcgatcat gtgtcggagc aacggaaatc atgcacatga ctccgttacg
     9841 gtgcagagcg tcatacagtg gttgctgttc aggcttcatc ttcgggccta cataagccat
     9901 tacctgtttc caggggatgc cggctttttc ataattatcg aattcttccc gattcttaca
     9961 ccagcaagaa aacatcgcat ccggtttccg gtcgagataa tagcgggctt gactggcgtt
    10021 atgtaccgtg tacatgacgt taacaggctt ttctgtttct ataaaatcag ccataacttc
    10081 taaaggtaca tccttgatat ccaaattcag gattgttttg cctttgctcc attccaggca
    10141 ttcttttaaa gttggaattt tgaaggctgt cacgttgccg tttcggtcca ccagattgaa
    10201 ttgttgcagt tctgcataag tgtaatctga aacctttcct ttcccggtag ttgtccggtc
    10261 gatggtttcg tcgtgcatca atacgattat cccgtctttt gtcaaacgcg gatctatctc
    10321 gaaaaacgat tccatatagg acaaggtctt ttcgaatgat tcgatgcagt tctccggata
    10381 gccgtctagc attccaccac gatgtccact gattacaatc gggcgatcgg gagcataccg
    10441 gaaataggct tgtagatccc ggctgttctt cacagtaatg taatgaggat tttgttcttt
    10501 gtctgaagcc aaaagattcc cggcaggcat aaaaccccct aaaaggagta ccaaaataaa
    10561 agatagcatt ttcatgatat tgtatttata tagattcttt gtcaattatg cggcttaaaa
    10621 gtaagacttt tttatcagtg gcgtactata aaagcactat aaaaacatga aaatatgaca
    10681 ggcaacaaga tgtgcaaaga aagaggcagg tatataaaaa attaaggatt gtcatctcga
    10741 caacccctaa ccaactttgt taaccttaaa tctaatacta ttatgaaaaa accacaatgc
    10801 aaaaatacac tagctaagct tgtttgtcaa accttttacg gataatatat gttaagctct
    10861 aatagctatt ttgtcaaaaa atgttggtta tttataaact atacagattc catgtaaaaa
    10921 ctgctaattc aaatactttt tatcgtcgga aaaagtgaaa tcccatgctt aaaaagtgtc
    10981 cccttggagt atataaaatc attaattaat ataggggatg ctttggtgtg gctgcttata
    11041 gataaattcc tttttggcgc atgcagcgaa tagatgatag attattaatt gttaatacaa
    11101 attaacgcat tatttcttgc acatttacga tgtattcgta gatttgcgat acgatcgtaa
    11161 aaaataatat agaaacatgg aaagattaac aagacaggaa gaggatgtaa tgcgctggat
    11221 ctggcagatc gagccgtgtt ttatcaaaga catcctggcg aagtatgaag agcctaagcc
    11281 tccttatacg acactcgctt ctattgtgaa gaatctggaa cgtaagaaat acgtgaaagc
    11341 gaaacgttac ggaaatactt acgaatacag gccgctgatc ccacaggagg aatataaacg
    11401 gacgtttatg ggaagtgtgg tgaacaacta tttcgagaac tcttacaagg aaatggtctc
    11461 cttttttgct aaagaacaga agatatcgac cgatgagttg aaagagatta tcgatatgat
    11521 tgaaaaagga cgagaataaa ctgttaaata cataatgcca tgacaccgga atttgcctac
    11581 ttcttgaagg taaatgtagc ttttatactc ctttatgcct tctaccggct gttcttttat
    11641 aaggacacct tctttaaact acgccgtacc atcttgttgg catttttcgg ggtgtcattg
    11701 ctttatccgc tgatgaatat tcaggattgg atccgggagc aggggccgat agtggaagtc
    11761 atacaaatgt attcagccat tttgcccgaa acgacaataa cccccggcaa tgttccccaa
    11821 acaaattggc atgatttgtt acttcccggt atttcttatc tttattggag cggtgtaatt
    11881 gccttatcgt tccgtttttt agtgcagttg agcagcatct tgttactggc acggcggtcg
    11941 gaagtgactt tgatccgtaa cgtacgtgta catctgttga ataaaccggc cggtcctttt
    12001 tcttttttcc ggctggtatt tctgcatccc gacagccatt ccgagaaaga gatcgatgag
    12061 attttggtac acgagtgtac gcatgtcagc cagtggcatt cgattgacgt gattatttgc
    12121 gaattggttt gtatcatctg ttgggtgaat ccgtttgtct ggctgttgaa aagagaggta
    12181 cgtcataatc tggaatattt ggcggatgat acggtacttg aatcgggcta tgacagtcgt
    12241 agctaccaat atcacctttt ggggttggca cataccaata gatcggtgac ctctttatct
    12301 aataacttta atatgctgca tctgaaaaat cggatcagca tgatgaataa gaaacgttcc
    12361 cggagcatag gtaggacgaa atacttgatt tttataccgg ttgtgggcgc cttgctgatt
    12421 ttaagcaatg tcgatgcatt ggcccggatc acggacgaac tgacggaaag cacgtttgcc
    12481 gatgtcttgc taccggaggc tatcttgccg ttcccttttg tcggtgatgc ttctcctgct
    12541 gaaaaacgtg aggagtatgt gctatcggag gaaggtattg aggctgccag acgtgcccgt
    12601 aacccggtgt ttaccgttgt ggaggtaatg ccggaattcc ctggcggaca gggtgctctg
    12661 ctgaaattcc tggcgacgaa tgtcagatac ccggaatcgg ccgttaaaaa tggtatagag
    12721 ggacgggtta gctgttcttt cgttgttgga aaagacgggg ctatctcgga ggcagaagtg
    12781 attcgtgggg taagtccgga actgaatgag gaggctttgc gtgtgataaa ctccatgccg
    12841 gtatggtcgc cggggaaaca gcggggcaaa gtggttaatg tcaaatatac ggtaccggta
    12901 actttccggc tttccggtgg aaagaaaaaa acatcctctc gtatcgtgca gaggcagatt
    12961 aaagaagtcg atacgtccgg tcgtgtcttt acggtagtgc aacagatgcc ggaatttccg
    13021 agtggacagg cttcgttgtt gaaatatctg gcaacacgca taaaatatcc ggctattgct
    13081 caggagaatg gaatacaagg acgtgtctct tgctctttcg ttgtcgacac ggatggaagt
    13141 ttgaaaaata ttgaagtgat ccgtggaatc gatccttcgc tggacaggga ggctgtccgg
    13201 gtgatccggg aaatgccgaa atggaatcct ggcgtacaaa acaatatggc tgtagccgta
    13261 aaatatacgg ttccggttac tttccgtttg cagtaattga ccagaatcgg tcattaatac
    13321 gataccatta tgaaatgtaa gttttctcta ttactgtttc tttgcgtact gtccctttgg
    13381 ggacaggcgc agagtcttaa tcttcaggaa ttggtcaata aaaaacaatt tcaggaagtt
    13441 gtagcacgtg cggatagtct tactcctgcc gattcagccg attatgctac aatgtcggca
    13501 atcgggcagg cgtatgaggg actgttgcgc tataaggagg cctatcagtg tttttctcat
    13561 tgcttgaaga tggatacgaa caatgtggat gcattgaacg ccgttgccag gaatgcgatc
    13621 aatttcggaa ggatagcgga agctaaacaa tgttatcgta aagtattggg aaccgacagc
    13681 atgaacttct atgccaacta tcagttggcg cgtctctatt atcagttggg agattatggt
    13741 cgagcgacgg aacactatca tatacttgct tccatcgaag gtgaaaatcc ttctatcctg
    13801 accgggctgg ctgattgcca tattaaaaga gggaccggtc ctaatacgat gatcgctctt
    13861 tctttgtatg cccgtgcttt ggagctgaac ccggaaaatg tacgtgtggc atcttctctg
    13921 ataaatacgt tattgcggat gggggacgga cagggagctt tgcaggtgtg cgataccgcc
    13981 ttgttctata atccggataa cagccagata cggcagagta aagggatggc tctctatatg
    14041 acgaaagatt ataagcaggc cgattcagtc tataccggtc tattggccga tggcgattct
    14101 tcttttttga atcttaaata tgcgggggcg gcccgctata tgtccggtca tgcacttgat
    14161 ggggtcgagc tgctggagaa ggcctatgaa atagattcga cggatgtgga aacagtcatg
    14221 ttgtatggcg cttccctgag aaaaacatac gaccgtaaac gggcttatga gcttttcgat
    14281 ctggcggaaa cgaatatgca gccgaaaaaa ttcctagtta atatgttgac gaccttccga
    14341 ggtgatgcct tggaaaggga cggccgttgg cccgaagcgg aaaagctgta ttatgccgca
    14401 tggaaggaag acccaaccca gttgcacttc ctgtataaga tcagtacaca atactgggat
    14461 gtcgatccgg gactctttca gcaggaggaa aaattgcaaa agacgatttt cagtagatac
    14521 acttacctga cagcctatat gaagacagac aagtcgcaaa agtatcttta taattaccgc
    14581 cctttcttgg aagcggtttg tgaagatgcc tttttccgga atgccgatga agtgacgatg
    14641 ttggctcccg atgggaagaa gacgaagttg gctgtcgctg atctgcgtgc cttggtcgcc
    14701 caactgccgc agatgccgga agatgaacgt ttgaggcgcg agaagatgca ggaacatatt
    14761 aaaaaagcca gggaaaaaga aaaggaattg cgtaaaagcg gtgctaaact cgatacgctc
    14821 gccctgagta aggaagaaaa agagaaagca cggaaaatgt tgaaagacgc cgacttggaa
    14881 tagatagaat atctgaacaa tataatcgat ataaat
//
