LOCUS       c00016_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GCHHHCKP_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 05:21:32
            Original ID  :: gnl|Prokka|GCHHHCKP_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 35211
            Orig. end    :: 58460
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[45211:48460]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1416..2873
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_35"
                     /sec_met_domain="FGGY_C (E-value: 3.4e-38, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 2.1e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(2985..3920)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_36"
                     /sec_met_domain="LysR_substrate (E-value: 1.6e-33,
                     bitscore: 107.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.8e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4036..5460
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_37"
                     /sec_met_domain="Lyase_1 (E-value: 1.2e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 4.4e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5569..7254)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_38"
                     /sec_met_domain="FTHFS (E-value: 2.2e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_39"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.3e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2.8e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_40"
                     /sec_met_domain="Spermine_synth (E-value: 4.2e-53,
                     bitscore: 171.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.3e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYTALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_41"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.9e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 2e-35, bitscore:
                     113.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKKAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_42"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.4e-14,
                     bitscore: 45.9, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENGIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_43"
                     /sec_met_domain="PAD_porph (E-value: 2.8e-128, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGDFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15367
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_44"
                     /sec_met_domain="CN_hydrolase (E-value: 5e-56, bitscore:
                     181.6, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGVYRKTHIPDDHYYQEKFYFTPGDTGFKVFGTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPRGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15595..16056
                     /locus_tag="ctg16_45"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGNPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16260..20969
                     /locus_tag="ctg16_46"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQLLEGQYAAETSQEGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSSQNPYLAAGNGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQIMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYVNSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20966..21853
                     /locus_tag="ctg16_47"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22045..23136
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_48"
                     /sec_met_domain="Peripla_BP_3 (E-value: 2.7e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 ttggaaactt cggacctgaa actcctgaaa ctctgatcgc agagagattt gacggacctt
       61 gtatgtatgt agcagcagca gaaggtgacg gtgatatgat caacggcaga ggtgatgctt
      121 actgtggtat gcttaactgc tcctacaact taaaaatgcg tcatctgaaa gcatatattc
      181 cggaatatcc tgttggaaca gcagatgata ttgcaaagat gatcgctgat ttcgtaccgg
      241 ttgcacgtgc agtcatcggt gtcagcaatc ttaagatcat tactttcgga ccacgtccac
      301 aggacttctt cgcatgcaac gcacctatta aaggcctcta tgagctgggt gttgagattg
      361 aagagaactc agagcttgat cttcttgttt ctttcaaaga gcatgaaaat gatcctcgta
      421 tcccggaagt ttgtgcagat atggcaaaag agatgggcga aggcaaatat tatgctgacc
      481 ttaatgtgaa aatggcacag tttgagctta cacttcttga ctgggcagag gctcataagg
      541 gagcaagaaa atacgttgca tttgctgaca aatgttggcc tgcattcccg tcacagtttg
      601 gatttgaacc ttgctatgta aatagccgtc tggtttccag aggaattccg gtatcctgtg
      661 aggttgatat ctacggagca ctcagcgagt acatcggact ttgcatttcc aatgatgcag
      721 ttacactgct tgatatcaac aactctgttc cacagtatat ctatgatgaa gatattaaag
      781 gaaaatacga ttataagctt actgatacat ttatgggatt ccattgtgga aatactcctg
      841 catgcaagat gtgtgattcc agagctgtta aatatcagct gatccagcac agacttcttg
      901 agccggcagg atctgaacca gacttcacaa gaggaactct tgaaggtgat atcgctgcat
      961 ctgacattac attctatcgt ttacagtgca attccgaggg cgagctggtt tcttatgttg
     1021 cagaaggtga agtactggat gtacctacaa gatcattcgg tggtatcggt attttcgcaa
     1081 tcaaagaaat gggaagattc taccgtcacg tactgatcga gggcaactat ccgcatcatg
     1141 gagcagttat gtttggacat tacggaaaag cattctatga ggtagtgaaa ttccttggac
     1201 tggatgttaa gaagattgga tataaccagc cggcaggcgt aagatacccg acagaaaatc
     1261 catggggtta atgagaaatc agtaaaacgg attattaatg ttcatgtgaa gtgaatgaat
     1321 ctgaatacag aataaataaa ctgacactat attaaaggca tcccggggct ttgctctggg
     1381 atgtattaga ttagaaatag aaaaggagag cacttatgta ttatattggt attgatcttg
     1441 gtacttccgc tgtaaaactt cttcttatgg aagaatcagg aaaaatctgt aacatcgtat
     1501 ccagagaata tcctttattc ttcccacatc cgggctggtc tgagcagaaa ccggaagact
     1561 ggtttgcgca gagtatggaa ggcatgaaag agctgacaaa ggatatcgac agagcgcagg
     1621 tagcaggaat tggttttggc ggccagatgc atggtctggt aacacttgac aaggatgata
     1681 atgtgatccg tcctgcaatc ctctggaatg acggacgtac aggcgaagag acagaatatc
     1741 tgaatacagt gatcggaaaa gacaaacttt cacagtatac agcaaatatt gctttcgcag
     1801 gcttcacagc accgaagatc ctctggatgc agaaaaatga gcctgagaac tttaagaagg
     1861 tagtaaagat tatgcttcct aaggattatc tggcatatcg tctgtctggt tctttttgta
     1921 cagatgtttc tgatgcttcc ggtatgcttc ttcttgatgt gaagaaccgc tgctggtcaa
     1981 aagaaatgtt ggagatctgt ggaatcacag aagagcagct tccgaaactg tatgagagtt
     2041 gggaagtagt aggaactctg aaacctgaga ttgcgaaaga acttggattc agtgagaatg
     2101 taaaagttgt tgcaggtgca ggtgacaatg cggcagctgc tgtaggaaca ggtacagttg
     2161 gtgacggtca gtgtaatatt tctcttggaa catccggaac tgtgtttatt tccagtaaaa
     2221 actttggtgt ggacgaaaat aacgcacttc attctttctg tcatgcagat ggaagctatc
     2281 atctgatggg atgcatgctc agcgcagctt cctgtaacaa atggtgggca gaggagattc
     2341 ttcagacaaa ggatttcgca gcagagcagg ctccaattca gaagctggga gagaatcatg
     2401 tattcttcct tccatatttg atgggagaac gttcacctca taataatcct gatgcaagag
     2461 gtgtattctt cggaatgtcc atggacagca caagagcaga catgacacag gctgttctgg
     2521 aaggtgttgc ctttggtctt cgtgattccc tggaagttgc aagaaacctt ggaatcaaga
     2581 ttgagagaac caagatctgc ggtggtggag ctaagagccc actgtggaag aagatcattg
     2641 caaacgttat gaacctgaag gttgatgttc tggagaacga agaaggaccg tccatgggtg
     2701 gagctatgct ggcagcagta ggctgtggtg cttacccgga tgtagaaacc atcggtaaga
     2761 aatttgccaa agttgttgat acggtagaac cggatcctga actggttgca aaatatgaag
     2821 agagatatca gaagttcaga actctgtatc cggcgatgaa gccattgttc taatcgaata
     2881 tctgcctgac atactggggt tgttgtgctt atttagcaca acaaccccat tttgacgtac
     2941 atctgatgat gaccaatcac catagcctat ttgattatga catatcagga aaagggcagc
     3001 ttcaggaatt cttccatggc tctgctgata tagcggcctt tcttccagta aaaaaacaca
     3061 gtgcgtttac tgctctgacc gggcagctta taaaaaacaa gttctgaatt tgttggaact
     3121 ctggagagca gaagatcccc gatgaaagtg atacccattc ccaaacatgc aatattatag
     3181 gcagtcatct gctgatctag gcgaaatact acagaaggcg aaaagtgatt ttcctgacaa
     3241 atggtaagtg cacgcttacc ggtatcatta tctgaacgaa gaataataaa tggttcgttc
     3301 tcgaatttgt ttaatggaac agaaggaata tgagaagaac ggaactgccc gttccggatt
     3361 tcctcaatag gaatctgata tttctgcagt ctggtattta ctgagtaatt tttgggaact
     3421 gcaagaagaa gttgttcttt ctggtagata taacgttcaa aaatctggtt atccagaata
     3481 cagttatcaa tcaccagatc taactttccg gcctggagaa actgggatag ttttgctgta
     3541 ctttcttcta caagagaaat ttgaacatgg gggaattttt gggaaaaatc agcaataagg
     3601 ggaggcagaa tccacgaaga aaaaaagtta ctgccaccta cattaagagt tcctgttttg
     3661 agatttccca gatccagtag gtagttttcg agattatttt caatatccat gactttttca
     3721 acagcctgta tataatgttt tccaacttca gttaactgca aaggtttggt acttcgatca
     3781 aaaataggat agccaatacg gttttccaca cgttttacat tggcgcttaa agaaggctgc
     3841 gaaatgaaaa gagcagcagc agctttggaa aagctttttt ccttgtagac ctcatagatg
     3901 tattccattc cctgaaacat ataaactcct ccgatatata atttaaacac tatatatttt
     3961 ataaaaatat atgtatttga ttatattata gcagagatat ataatgaggg caaatacatg
     4021 ggagggcgaa taactatgaa aaaaacagac tatcgtgtag aaagggattc tattggtgta
     4081 aaggatattc cggaagatgt atattatgga gtacaatcct tacgtgcggc tgaaaatttc
     4141 cacattacgg ggctgaatat gcatccggaa attattaaca gtcttgcata cataaaaaaa
     4201 gcagcagcga taaccaattg tgaggtgggg cttcttgaga agaaaaaagc acaggcgatt
     4261 gtccaggcat gtgatgaaat tgtttcagga aaattccata atgaatttat tgtggatcct
     4321 gttcagggag gagctggcac atctttaaat atgaatgcca atgaagtaat tgcaaatcgc
     4381 gcgattgaga tactgggagg aaaaaagggc gattatacaa ttataaatcc taacgatgat
     4441 gtgaattgtg gacagtctac caatgacgtt attcctactg ccggtaaaat gacttctctt
     4501 cgtttgttgc agaatctgaa aaaacagctt cttcgcctct atgatgctct taatgaaaaa
     4561 gctacagagt ttgatcacat aataaaaatg gggcgtacac agatgcagga tgcagtacca
     4621 attcgtctgg gacaggaatt taaggcatat tcggtagcaa tcatgcgtga tatccacaga
     4681 atggataaag caatggatga aatgcggact cttaatatgg gaggtactgc tattggaaca
     4741 ggaattaatg cagatgaggg ctatctgaga agaattgttc caaatctcac tgaaatatcg
     4801 ggaatggact ttatacaggc ttttgatctg attgattcca ctcagaatct ggatccattt
     4861 gtagccgttt ccggtgctgt gaaagcatgt gcggtaactc tttccaaaat gtcaaatgat
     4921 ctccgtctga tgtcctccgg tccacgtact ggttttgggg agattaatct tccggcaaaa
     4981 cagaatggtt cctctattat gccaggtaaa gttaatccgg ttattcctga agtagtgaat
     5041 caggttgctt ttaatattat tggtaatgat gttaccatta ccatggctgc agaggctggt
     5101 cagctggaat taaatgcgtt tgagccgatt attttctatt gcatgttcca gtctatcgat
     5161 actcttggct atgcagtcca gacattggtg gataattgta ttgtaggaat tacggcaaat
     5221 gaagaaagat gccgttatct ggtagaaaac agtgtaggta ttatcactgc aatcagcccc
     5281 catcttggat atcagaaggc tgcggatatt gcaaaaaagg caattaagac aggcgaatct
     5341 gtaagaagtc tgattctgaa agaaaagctt atggacgagg atgaacttaa tcgcattctg
     5401 gatccgatcc atatgacgga acctggtatt tccggaaaag attatcttat aaaaaaataa
     5461 agaaaaaaac aggcgggaaa atcttcccgc ctgtaaaatc gtctggacac atatcatata
     5521 taaatatgat ttttatattt ttgaattatt cgattgattt caaccggatt agaacagacc
     5581 tgtgatctta cctgtctcgt ctacgtcgat tctctcagca gccggaactt taggaagacc
     5641 tggcattgtc atgatctcgc ctgtaagagc tacgatgaat cctgcaccag cggaaatctt
     5701 caggttacgt actgtaactt caaagtcagt aggagcaccc agtttggtct ggtcatctgt
     5761 taagctgtac tgagtcttag ctacacagat cgggcagttg ccgaatccaa gagcttctaa
     5821 ctgtttcgcc tgtttctgag cgttagctgt cagaactact ttcttaccgc catatacttt
     5881 ctgaacgatc tggttcagtt tgtcttcgat agaaccttcc agttcatatg cataggagaa
     5941 gtcgtttggt tcttcaacaa gacggataac ttcttctgca agtttgattc cgccttcgcc
     6001 gccttttgcc catacttcag aaagagcaac gttaacgccc agttctttac atttagcttc
     6061 tacaaagtca agctctgctt ttgtatctgt agggaatgcg ttgatagcaa caacacatgg
     6121 aagtttgtat acgtttttga tgttggaaac gtgttttaac aggttcggga tacctttttc
     6181 aagagcttcc aggttttcat tgttaaggtc agctttagca acgccgccgt tgtatttcag
     6241 ggcacgtact gtagctacga ttacaactgc gcttggtttt aaaccagcca tacggcattt
     6301 gatatcaagg aatttctcag caccaaggtc agcaccgaaa ccagcttctg tgattgcata
     6361 atcagcaagc ttcatagcca tctttgtagc tgttacagag ttacatccat gagcgatgtt
     6421 tgcgaatggt ccgccatgta cgattgcagg aacgtgttcc agagtctgta caaggtttgg
     6481 tttcagagca tcttttaaca gggctgtcat agcgccttct gcgtgaaggt cacctgctgt
     6541 tacaggtttc tgctcggaaa cttttccgta tgtatatccg atgataatct tggataatct
     6601 ttctttcagg tctttgatgt cgcttgcaag acagagaact gccatgattt cagatgcaac
     6661 tgtgatgtcg tatccgtctt cacgaggcat accgtttgtc tttccgccaa gaccatctac
     6721 tacgttacga agctgacggt cgttcatatc tacacatctt ctccatgtga tcttacgtgg
     6781 gtcgatgttt aatgcattgc cctggaagat atggttatcg atcatagctg ccagtaagtt
     6841 gttagctgcg ccaatggcat ggaagtcacc tgtgaagtga aggttaatat cttccatagg
     6901 aacaacctgt gcatatccgc cgcctgctgc accacctttt acaccgaata ccggtcctaa
     6961 ggatggctca cgaagagcta ccataacact cttgccaagt ctctgcatac catctgcaag
     7021 acctacagta gtagtagttt taccttctcc tgctggagtt gggttgatag ctgtaacgag
     7081 gattaatttt ccatccttct tatcactttc tttcagaaga ttgtagtcga tttttgcttt
     7141 gtattttccg tactgctcca gatatttgtc gtcaatacct gctttctctg cgatctgagt
     7201 aattggaagc atctcgcatt cctgtgcaat ttcaatgtct gatttgaatc ccataattgt
     7261 ttttctcctt tcgtttccgc ataacatgaa aaacttctgt tgctgttcac tccgcgatca
     7321 gcaacaatta ttaattgaaa gaagtattgg ccggtctgcc tggtattcct gatttctgcc
     7381 ctgaaagtta taaaaaaggc cagtatctga atatttcaaa tactgcccag acggtcggct
     7441 cccacaaacc tccgactcca cgtggtttgc actccactct ttccgtcagt actcgaaggt
     7501 tctttcaatt gatgaataca atatatcatt ttgagaaaaa aatgtcaaga aaattttgtt
     7561 gaaacgtcaa aaaatgtgag taaactggat aaaagttgtg caaattgata agagaagaga
     7621 atcgtaatcc ctggtcatga aagaaaatac gttttctcaa ggaaagaaat tgttaaaaaa
     7681 taaacacagt tttccctgat aaatgaagaa aatataaaaa gcgggtaaag ctagagcgtg
     7741 tctgaaaaat cattcccgca atctgtacgc ccccactttg cgggatattt cacccgaatt
     7801 cagttgccgt agcccgctac ggcgccctca tccgggcaaa atatcccaca aattgtgacg
     7861 cacatcttgc agaaagcctt tttcagacac gctctagtgc aaaatatgga aaatggaatt
     7921 gacaacagtt cagaagatat gttattctca tctttagtat gaaaagacac tatcgttttc
     7981 atgcaaatat ttgctcacat tcagagacag tttctgaatg ttaagccata cggacaggcg
     8041 gggcagttgc cgggtgggag acaccacatt attgattgag ttagaagctc aaattttata
     8101 agttgattac tttataataa tcagtgcgta agcacacatc atcttgtgaa acggtcaata
     8161 agagcatagc atatatttgc cagcgattga agacgacagc agtcatgaat atttcagaat
     8221 acgggaacag gcacaggata cagacggatt tatacgggaa atccggtcag tatataaaga
     8281 gacagagcct gagaaattct atagatcatg agagaagcag atggtgaatg aacttatctg
     8341 cttctttttt gtgcagatat agcaaatata aaggatatgg ttggagataa acgctttgcg
     8401 aggatgtgtc tcacatgcgt tcgacttgaa tatatagaga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccagagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc atccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agccaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcacttagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggcatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccatcgg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta taagaaggac agtacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaaca tcttcaggtc ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaga tggttacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttatac ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaagatagat
    11041 gcggataatg cagcagaggt cgcagaattg attagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctacgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taagaaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgcc tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgatttccc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatc
    11761 gtgccgattc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgcgct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc gtatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcaa ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg agaatggaat
    12901 cagaacgctg attttggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt aatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcgggt acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttccggt gtgactttgc tggaatgtga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggagga gactttgatg gactttaccg gaactgggag aaggacgaca
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccgg gaagatgtgg atggttttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttacgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gtcggcggtg
    14341 gaaatattca ctgtattacc cagcagattc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgaggggtat tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct tccggagctt tttgaacggc cctatttctg
    14641 ccaggagcgc agatatgagt attatgaata tgcgcagact gcagaggaaa accctgcagt
    14701 gcgtcatttc agcagggtag cggcagagct ggggattgtg atcccggtca gcttttatga
    14761 aaaagaggtc aataatactt ataacagcgt tgcggttctg gatgcagatg gaaagaatct
    14821 cggcgtttac cggaaaacac atattccgga tgaccattat tatcaggaaa aattctattt
    14881 cacaccggga gataccggct ttaaggtttt tggtaccaga tttggaacca tcggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac ggcaagatgt atggcactgc agggcgcaga
    15001 gcttctcttt tatcccactg ccatcggaag tgaacccatc ctggaatgcg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaac ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggctctt cttttatcac agacaacaca ggtgctctct gtgcagaact
    15241 gcccagaggg gaagaggggg tgcttgtaag cacttttgac ctggatgcat taaaggcaga
    15301 cagactgaac tggggacttt tcagagaccg cagaccggag atgtatgcaa aaattgtcgg
    15361 gaaatgacat acaagccaaa attccattgc cgcaggcaat ctggaatgaa ttttggatca
    15421 gttactgaga acggagtgaa cagtaactga gtttataaga atttcataaa aagtttatga
    15481 ttatattagt tgctacctgc ggtatatatg gtaaaataag agtacgaacg ttactgataa
    15541 cggagagagc agtagagttt tgatatgtat ttctggcaaa atggagtgta gaagatgaac
    15601 agaaaagaat ttttggaaat cctgagaagc cagcttgccg ggcagatgca ggagggcaaa
    15661 gcagcagcac atatcaggta ttatgaagat tatatacagt ctcaggtacg tggcggacgt
    15721 tcagagcagg aagtactgca ggaactggga aacccgcatc tgatagcaaa aactctgatc
    15781 gatacagatg atggaagtac acaggaagat tacggagagt attcttctta cggaagcagt
    15841 tatggcaatg agacagagct tcctcatcag caggagaaaa gatggaaaaa agtaatcgat
    15901 ctttctacct ggcatggcag ggctgttgtt attgcagcgg cggctgttat aattgtttta
    15961 ctgatactga taatcggagt tgcgattccg ttttttatta ttcttgcaat tattctttat
    16021 tttctttcat ggctgaagaa aagaaatgat caatgaaaat ctgtgcaggg tttcagaaaa
    16081 gaaaccctgc gcagaatctt aaaaatctta agtgtaaacg ttcttgtttc acgatattaa
    16141 ttccccttga atatttataa tcatacaatc tcaacttatt tctattcttt aatcctgcca
    16201 ggtgcaggga aaaatcccac attcattttt atattttttg ttcggaaagg agacggaaaa
    16261 tgaaacacaa tttcaaactg aaagaacgcc ttggagcttt gctgcttgca atgcttttta
    16321 ttctgcaggc aattctgggg cttgtgcctg tctgcgtaac tcaggcggca ccgttaactg
    16381 tagaaacatg ggacagtgac aaggtggtag attatggtta tcgctttaac atgaagtttc
    16441 agcccggaat taccacatat gaatcttttg ggtgtgataa tctggacagg gaagcttttt
    16501 cagacaatgg aaaaagcgaa cgtgatacag agtgcgttcg tgtaggagcg gactataaag
    16561 ccggaagcgc agggatgcgt tataacaatg taggaaaaga tggaaatgga aatattgttg
    16621 atgtcagact cattcttgtg ggagtagaga atgcagaacc ccgttatgat ctgcgcactg
    16681 cagaatcgat tgttcagaat aaaggcggag ctacgtttgc atggaaagat aatgaagctt
    16741 atccgatggt tggcttttcc aaaaacagta tcggtgtatt tatttattct gtaggatacg
    16801 caaaggttaa atttcagttt ctgaagcatg gaacagaaga aacactgccg atcagtggac
    16861 atggaaccat acgtgatatt gatgcgggac agggagtccg tattccgtca gacagcagtc
    16921 tggataatgc atatgttctg aaaaacaatg attatctgac ggtagatggg aattctgtaa
    16981 gctcacccct tggttccgtt gagccggatg atccgagagg atggctgaat cttttttata
    17041 atacagataa ttttacggta gaattctgtc atcagttcag actggataaa tgggataaaa
    17101 gtcgtgaaga tgccattgca aaagccggtt ctcaggaaag atgggcagag attacaagaa
    17161 ataaatatct ggatccatca ggcaacagtt attgtccgaa ctttaaagga cagaaatact
    17221 gcaaagcata tgcatatttt gattttacat cctattgttt cggtgatgtt gagatgaaaa
    17281 aagcgcctga gaaacgtgtg ggagaggcaa actgtacatg ggaacaggca gctgccgcat
    17341 caaaagaaaa accttttggc attcgtcagg gacaggaatt tcagtatatg atccgggcag
    17401 aggtgacacc caatagactg aaatcctttg tggtacagga tatacttgag gattgtctta
    17461 ctatagagga tgcatcaaaa gtcagtattg tgaatgatgc agggcagaca gtgacagact
    17521 ggtttgatgt tgctgttgaa ggacagaaag tgacctgcag ggccaaagca gagagccttc
    17581 aggatgaagc atttacagat aatcagactt acacatttac tttaaaagta cgccagagac
    17641 cggaatcaga aattaacatt tcaaaatacc ttgcagagga tggatacagt attcttgtac
    17701 caaaccatgc atccatgagt tatgaacgta caaacggaag cggagataca atggatacgg
    17761 aaacagtgtg ggtaaagggt gtgattccac cggaactgga agtaaagaaa aatacttctc
    17821 agtatgaatg gaaaacggga gatatcatag attatgaggt tctggtttct cagacaaaac
    17881 aggatgtaaa agcagtaaat gttgttatta cagacgagct tccatcatgt ctgcaacttc
    17941 tggaaggaca gtatgctgca gagacaagtc aggaaggtga gaactgtacg cttaccggac
    18001 agggagaaaa tggatggaaa gcagagtgtc cgtccctgaa gtatggggag acgatcacaa
    18061 tccgttttaa atgtcaggca tctgcggatt ccaatggaca ggaatgggaa aatattgtga
    18121 ctgcaacagc ggataatctg atcaatcctg agacaggaga acaggaatcc agaaaggata
    18181 tggcagaagt atggccgaac agtccacagc ttgaaattga taaaacagca gacaaatatg
    18241 aatggcaggc aggagagcag gtagcttacc ggatcgtggt gaataatgta acggcaggaa
    18301 caattgcaaa agatgtaact attactgata ttggtctgcc gcagggactg gttctggcag
    18361 gtggtgcaca gagcatggaa gtactgggag ttcagcaaca ggtaaactat cccgtaccgg
    18421 ataagaaaac aggacaggca tatgaagcga gacctgtgga ttctcagttg aatgcagatg
    18481 agaacggatt ttccttttat tgttcttatg tgccatacag tcagcctgta acgattattt
    18541 tccattgtat cgcacaggaa gaggcaaatg gacacgaaag cgtaaatgca gcaactgtaa
    18601 aagctgctaa tacagatgag agatctgatg atgcagaagt atatgtaaat tcaggagaat
    18661 tctggattga gaaatctgca gatcattatg aatggcaggt cggagaacag gtacagtaca
    18721 atgtggtggt ggagaataaa aaagcaggta cagtggcccg gaacgtaact gtctgggata
    18781 ccggtatgcc ggcaggactt gcgctttcat cggcagagga tgtatcggta agcggaatcc
    18841 cacagaatat tacgcagctg acagcaggga ccaaagatgt tttgaaccag ctcaatccgg
    18901 aattttataa tgagacatca gagaaaccgg tgaattatga atttcttcag gagggaagcg
    18961 gatggagact gaacatttca gatcttccgg caaatactcc ggttatgatt tctttccttt
    19021 gcacagttac ggaagcggca aatggaatgg aaagcattaa tgttgctaat gtgcaggcgc
    19081 agaatgcccc tgtttcacag gatgacgcag aagtgtatgt aaatacagca gttctttcta
    19141 ttgagaaaag ttctcagaat ccatatctgg cagccgggaa cggacgtgcg gaaaatgaat
    19201 ttcgggtagg agaacaggtg aattatcagg ttacggttaa taatcttcag aagggatcta
    19261 tcgcaagaaa tcttgtgatc agtgatcttt cccttcctga agggctggct ctggacggag
    19321 ctgaagatgc tgttactgta agcggtgttc cggctgttat tcagaatccg gtggcaggaa
    19381 ctgatgatgc aggaaatcag ctgaatccgg aaaattataa agaaacagtg gaaaaaccgg
    19441 tcagctgtca ggttacacgt cagggaaccg gatggatcgt gacgatttca gatcttccgt
    19501 atcagacacc tgtgactgtt aatttccgct gtactgcgca ggaaagcgta aatgggatgg
    19561 agattgtaaa tacagcacag gcgtatgcag ataatgcaca gaaagtaaag gactcctcaa
    19621 aaatctgggt gaactcgcct gttcttaaag tagagaagac gacggacaaa ccattttaca
    19681 aatatggtga tattattaca taccgcattg tcctgacaca ggagcagacc ggatgtgtgg
    19741 cgcgtaatgt tactttgcag gatgtgatcg atactcaggg agtacgtctt ctgaaggatt
    19801 cggtgattct gatggatgag aaaggaaatg tagcagatgc tgatgtacag atcaatgatg
    19861 ataatacttt cctgatgtca acaggcagga cactggtcag ggatagcaga tatagtatct
    19921 gcgataatga taaaggcggt ctttttgagc agataatgta taatcctctg gactgtcagg
    19981 aacagaaaag tatgatcgtg gaatatcagg cagcggtgat tgatgcagcc ctggcaggac
    20041 agaaagtgca caatactgca gttgcagaca gcagtgaaaa gatacctgca accggggaag
    20101 cagagacaga ggtacacagt ccgattctgg aaattgtgaa ggaatcagat aagaaagagt
    20161 atgcgtccgg tgagaaagga tactataaac tgacagtaag acaactgcgt gaggatgtca
    20221 cagatcagaa tattgttatc gaagataaac tggaaaccca aggggcttcc attgtaaaag
    20281 acagcatttt tgtgaagaaa aacggtatag aactgaaaga tgccaaaata gaggcagatg
    20341 atacaggatt tgtaattcag acaggagcat cgttgtcaga tatggataaa attgaagtct
    20401 gctatgaaat ggtatttaaa acagaaagca cagagcctga aaaaattgta aacacagcga
    20461 aagcaagagg tgatatttca ccggaaatta ctgcacagca ggaggcatat gtgaaagcaa
    20521 aagcagaacc gactgccaca ccaacaccgt ctgcaacacc gaaaccaaca gaaacaccaa
    20581 agccgacaga gacaccaaaa cctacagaag taccgaaacc gacggagcag ccaaaagcca
    20641 caccaacacc atctgtaccg ggaacctgcc cgaaaatgac tcctgtaccg acgaaagcac
    20701 cgttagcatc ttacaatggt ggaaataatg gaggcacgac ttccggaagc ggaggcagca
    20761 gttacgtaaa ttcgggtgga tattccggtg gatacggaag ctatcagggt ggttccatgg
    20821 caggaagttc taaaacagga gatgtcagac cgtttaaaat gatggctgtt cttggcctta
    20881 tcggaatggg actgctgaca ggaggtgtgg tgatctacag aagaactgtt tccgggaaaa
    20941 gaaatataaa gggtatgccg cggaaatgaa aaaactcaga acatttgcag taagtatgat
    21001 catagcagca attgggcttc ttatatattg tgccggcttc tatataaaaa gttatgaaca
    21061 gaatcttgca gcaaggcagg aatatgcaga gctttcccaa atggcagggg tgaagaacag
    21121 agaaggtgct ggattattgg cagatggcaa aaaaactgat gaagacagca gtacaaaaaa
    21181 cagtgaaaaa aaacgcagga aaaaacagag aagatcttct gaatcaaaaa acaaaaactg
    21241 tacagatgaa atcagggaat ccttcgggat ttcctgggaa aatttaagaa agatcaactc
    21301 tcagacagtt gcctggatta ctgtcccggg agccgatatt tcttatcctg tagttcaggc
    21361 ggcggatgat gaatattacc tgaaacataa tttcagagga gaggaagatc tgtttggatg
    21421 tatttttctg gaacatgaca taaaaaagaa ttttacagat tcccacagta ttctttacgg
    21481 gcataatata gaaggtaata tgatgtttgc aaatctgaac cgttatgaac agcctgaatt
    21541 tctgaaaaaa tgtcctgaaa ttgagatcac aacaccaaaa agaaagtttc tgtacaaaat
    21601 tttttctgtg gaacaggcat cttcccaaag cccggcattt gaatatggat acaagttatc
    21661 cagtcctgca tacaggagac aattatctat attgaaaaat aattccatgt atgacacagg
    21721 agtagagcct gatgaaaggg agagaatggt gactctgatc acctgtaatt cacgtctgga
    21781 taaagaaata cgtatggcgg tacatgggat ttgccatgaa tgttatggta tagaaaaagc
    21841 tgagccgaag tgatgttgaa atcaatcgga tattggtaac tttcgtaaag gatgaactgt
    21901 tactgttcac acatcactat ccctcgaggt gttttggaaa aaactaatga aaaatctctc
    21961 gatattttgt ataatttatg cataaaaaac aacttgttcg tacgtgcgta caagttgtat
    22021 cctaaataca ggagggaaga agacatgaca gataatggaa agccgaaata tttctcactg
    22081 atggaacagc tcagaagtga tattatgtca ggagctatcc gaccgggaga gaagcttcct
    22141 tcagaaaacg agctttcaca gaaatattcc ctgagtagac atacagttcg taaagcactg
    22201 ggaatcctgg agcaggacgg atatgtagag gcatttcacg gaagaggtac ttattgctct
    22261 gagaatatgc gccatataaa gaattcaaag aatattgcgg tagtgaccac atatatttct
    22321 gattatattt ttccgagact gatacaggga atggataatg tcctttcaga aagcggttat
    22381 agtattatcc tgaaaaacac agcaaacagc agacagaaag aggccagatg tctggaggaa
    22441 cttctgaaga aagatattga tggactgatc attgaaccaa gcaaaagtga gatgatctgt
    22501 aaacacagaa atctttatca gaatctggat aaatttgaaa ttccgtatgt gtttattcag
    22561 ggaatctatt cagaaatgag agataaacct catattctta tggatgatgc acagggaggc
    22621 tatcttgtaa caaaatatct gctggaactg ggacataaaa agatcaaggg tttctttaag
    22681 gcagacgata tgcagggact ggagcgccac aagggatatg tgaaggcttt acaggagtca
    22741 gggattgcct atgatcctga tgatgttgtc tggtttcata cagaggacag gaaagtaaaa
    22801 cctgcactga tggcaaaaga aatggtacag agcggacagc ttccggatgg aatcgtctgt
    22861 tacaatgatc agattgctgt tcaggttatg gaagaactgg agaaaatggg agtcaggata
    22921 ccggatgata tttccattac cggttatgac aattcactgt atgctcagcg aggaagcgga
    22981 atcacaacga tagctcatcc gcaggaaaag ctgggagaaa tggcagcaga gcttatactt
    23041 gagaagatca acggagttcc tgaagaagaa agtaaggttg aaagactgat ttatccggaa
    23101 ctgatcatac ggggatcatg cagaaaaata ttgtaaacaa atgaaataaa taaaaaatta
    23161 atccaggagg aattttatca tgaaaacagg aagaaactat aagttctggt tttgtacagg
    23221 ttcacaggat ctttacggag atgagtgct
//
