LOCUS       c00057_gnlPro..        14462 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GCHHHCKP_57.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 05:21:32
            Original ID  :: gnl|Prokka|GCHHHCKP_57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14462
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14462
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5051:7303]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5052..7303
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14462
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14462
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1197..1556
                     /locus_tag="ctg57_1"
                     /transl_table=11
                     /translation="MPKTSYICNCDVIHEDIVNDVKSKMQPKDDYIQLASLFKLFGDGT
                     RVQILHALEQSEMCVCDLAVLLGVTKSAISHQLKALRLANLVKFRKEAQIVYYSLADDH
                     VKEIIDKGFEHLWQK"
     CDS             1616..3970
                     /locus_tag="ctg57_2"
                     /transl_table=11
                     /translation="MKRIFLLKGLDCPNCSAKIEKEVGELDGVQSSVVNLMKQTITVNV
                     TQTAADTIASQIETIVYSHEPDVEVQEETVMNVTKSYSLKGLDCPNCSAKIEKEVGELD
                     GVQSSVVNLMKQTLTINVAQTAADTIASQIETIVHSHEPDVEVSEIVQESYIPEKKQEA
                     NESYNNEDKKLTVRLATGAAIYAIGMALTVFAKVPLPIELAFLIVSYVILGGDVVWQAV
                     RNISKGRVFDEHFLMSVSTIGAFVIGEYPEAVAVMLFYQVGEFFQSLAVKRSRKSISDL
                     MDIRPDSATVRRNGELITISPENVSIGEIIIVKPGEKIPLDGVVLDGDSMLDTRALTGE
                     SVPRSVHKGDEALSGCMNQTGVLMIKTTKAFGESTASKIIDLVENASSRKAPTENFITT
                     FARYYTPVVVILAAFLAILPPIILGGGWTEWIRRGFVFLVVSCPCALVISIPLTFFGGI
                     GAASKRGVLVKGSNYLEALNNVSVIVFDKTGTLTKGVFNVTDILPANGFSKEQVLEYAA
                     EAESFSNHPIAKSILAAYEKEIDQSVISDYKEISGYGISVMAGEKKVFAGNTKLMDTEC
                     IEYTTCEKAGTKVYLAVDGQYAGCILITDEVKPDSKKAISDLKHIGVEKTVMLTGDDEK
                     IGKSVAEELQLDKYYAQLLPDQKVEKVELLDSKKRPGSKLAFVGDGINDAPVLARADVG
                     IAMGGLGSDAAIEAADVVLMTDEPSKLVDAIEVAKATKQIVMQNIVIALGIKSVFLILG
                     ALGIAGMWEAVFGDVGVTIIAVLNAMRILKK"
     CDS             3987..4505
                     /locus_tag="ctg57_3"
                     /transl_table=11
                     /translation="VKRKLILLVVTIVFLVGFGVILHSPPSMIDAVTGATPKSKKAAQA
                     SAQLEGSYVLGINMMSDGLDNENTRNKLKELALDDSETNETDLMKTDISFRLYVSETDY
                     PLVSYAKKLCDRLKQAGFSVDLKEYSNTMMLSRVVSGKYDVFLASDDFIDVTTLTQMDY
                     MIMDSEEMR"
     CDS             4516..5055
                     /locus_tag="ctg57_4"
                     /transl_table=11
                     /translation="MRKWNTILSVLMLLIFMIHGIMGSFMLNGVGSSAGKLLAWIGVGI
                     LVVHTVIGVILTVQSLQTAKQSGKMYLKQNAIFWARRASGMAILILLLFHIGLFGKVQN
                     GTYILFPFTTVKMVTQLLFVAAIFVHIFINIRPLLVSLGIISYKERRSDIYLILSVLLL
                     FIAGAVILYYIGWQYL"
     CDS             5052..6596
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 268.8; E-value:
                     3.1e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 7.1e-83, bitscore:
                     268.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3e-17, bitscore:
                     52.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINTALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEASGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANSEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSAREQ
                     ADVVDLSCATQIDFPPTSQISEIKQLNKVMQDTMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDDDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             6602..7303
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 91.5; E-value: 1.1e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_6"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-29, bitscore: 91.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00059, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVYKIRIRRQESQKSDSYWQEFEFDGSKNSSVANVLKELNSRTPL
                     KDNSGNIVTPISWECSCMVRKCGACAMLINERPRLACSTFLHTLKGSTITLEPLSKFPL
                     VRDLIVDRSILFENLKKLNLWLESEAYMNRWTHEPRYQSARCLMCGCCLEVCPNFSANG
                     TFAGAVAAVNAFRILNEEQESTHLNEISAEYKKKYFEGCGKSLSCHDICPIGLPLEELL
                     VRSNAAAVWGK"
     CDS             7328..8071
                     /locus_tag="ctg57_7"
                     /transl_table=11
                     /translation="MYEENQKLKTWITPDLATEYLAGAVLLGAAPCTAMVFVWSTLTKG
                     NPAYTVVQVASNDIIILFAFVPIVKFLLGVSNVSVPFQTLFMSVVLFVVIPLVAGIITR
                     LLVVRKKGTEYFEQTFLHKFDSATTVGLLLTLILIFMFQGEVVLDNPLHIILIAVPLII
                     QTFFIFSLAFGVCRIIRLPYDIAAPAGMIGASNFFELAVAVAVALFGTSSPAALATTVG
                     VLTEVPVMLTLVKIANKLKEKFKYE"
     CDS             8064..8477
                     /locus_tag="ctg57_8"
                     /transl_table=11
                     /translation="MNKKKVAFICVHNSCRSQIAEALGKHLASDVFESYSAGTETKLQI
                     NQDAVRIMKELYGIDMEAEGQYSKLIDEIPVPDIAISMGCNVGCPFIERPFDDNWGLED
                     PTGKSDEEFKKVIDEIRMQIFILKQRLDEFEEN"
     CDS             8787..9026
                     /locus_tag="ctg57_9"
                     /transl_table=11
                     /translation="MRTIYAEYNINHDSIDVYTSAGYMLRIDCWEAEKDLKTTYGSECA
                     LTSLAVDEPLEYARLYLEGNLQMWVDAEDSLELY"
     CDS             complement(9103..11310)
                     /locus_tag="ctg57_10"
                     /transl_table=11
                     /translation="MYAKLVFRNAKRSVKDYLVYIVTMTICVTLFYAFLSISSSYYSPD
                     IGSEYDFTLLSDGMKIAICMITLLLLFLIRFVNHYMLRRKQKEFAVQSIMGMEQKTIGR
                     IFFAETLIMGMFSILIGIFCGVFCSQFITAMLLTAYGKPYEISWTLFPDTVLLTVVFFV
                     ASFFVVGIFNTRTIQKTKIIDMLSAEKENEPELKKSRFISVVVVLFEVFTVWGLMTGIQ
                     KVWFYYDTRFAFPVQLMFWGNILFPLLTLLWSIFCIIRKKKRECFIAGLLICSVLNAFT
                     AASVAALTNKYYLSLGGGTLNQYLLFVVIDLLFFICAFIYLTSGLIVAWKGKSPEHRYK
                     GENLFFFGQIISKLNTTSKTMTLICITLVLAIFMFIAAPILTGWASGYLDMRSMYDVQV
                     YSRYNDVYEEENLPQDSYEIITDFLTEHKIDTVYDCTFNLYLSEKDDFHNRQKYDFPIV
                     AISLSDYNTIREMLGYEQISLEEDEFTTQWKAIATEEERDNFLKEHASIMTDAGELTLS
                     GQSYYEDPIGETAYNSYTNVLYVLPDNICEKLLPVIKNRYITTTENISYENARKLEKLF
                     TEKYPEQAETGAIYGVRFSTLQINSSIANNFILQTSMIYGAVVLMVICLTVLSLQQLLD
                     AGQYKYRFSVLRKLGVEEKHIGKLILKQLSIWFGLPIITAIIVAAVVIAYFIQTISAEI
                     SAYIGFSTLMLQIGATMGILAILLICYFISTWIIFRRSVNP"
     CDS             complement(11300..12067)
                     /locus_tag="ctg57_11"
                     /transl_table=11
                     /translation="MNTILKLEHIQKYYGNEGNITKAIKDISFSVEAGEFLGIMGASGS
                     GKTTLLNCISTIDTVSAGHIFLEGTDITEINPKSLARFRRENLGFVFQDFNLLDTLTIS
                     ENIALALAINKVPAGSVEPRILDIAGKLNISDILNKYPYQVSGGQKQRCACARAIINNP
                     KLLLADEPTGALDSHSSQMLLSTIQSINEQLRATILMVTHDAFTASYASRILFLKDGEI
                     FMELRKGNDSRSDFFDKILNVLTMIGGGQSHVC"
     CDS             complement(12179..13192)
                     /locus_tag="ctg57_12"
                     /transl_table=11
                     /translation="MSGKQYLKNQLPVILINLLGMLVLALFLIASDNPIQTVLFIFAVW
                     SIVLVLSLLAFYFSRKKYLNKLLNMTEQLEERYLLPEIMQVPERADEQVFYQIMKMAEK
                     SMLERIGEVQRERREYKEYIEQWIHEVKTPITAMKLLCENNRSPFSREVLAELENINQY
                     TEQALYYARSEHAEKDYSVREVNLCDVVHSAIADNKYLLRQSNMSIQIDDIETKVYTDE
                     KWVRFILNQIIGNAIKYHAEQPILHFRATKTNDKIVLSISDNGIGIPKSDLPRIFEKGF
                     TGQNGRTGKNSTGIGLYLCKRLCDKLGIGLTAYSENRGTTISLIFQMNDFIIGVQG"
     CDS             complement(13189..13857)
                     /locus_tag="ctg57_13"
                     /transl_table=11
                     /translation="MKEKILIIEDDFTIQTQLKTLLSGNGYEVFAVTDFSKTIEQLKEA
                     APHLVILDIKLPGNNGFEICSGIRTFSDIPIVFVTSSNTDMDELNSIMLGGDAFITKPY
                     NPAILLAKIAALLKKAYRSPQTEIYMWREATLHLESSMIEYKGQKAELTKNELKILYYL
                     FKNSGKICSRNDIVDFLWDNQLYVDDNALSVNITRIRDKLAAIGLVDFIKTKHRQGYTL
                     "
     CDS             complement(13966..14460)
                     /locus_tag="ctg57_14"
                     /transl_table=11
                     /translation="FQTTLFLLAWYSLTTTLFQAVQSDVLLSDCKSFFHDAASFIQTFI
                     GWTIEVGQSVAQISTKIPNPFIAGMVYWILLILIVGICVAGTGILAILIEIKVIELYRE
                     KCWDVITLLMILTSAAVIIYFGEAIKKALSVNLLLLFVLLQGAYVGLRCYLESYLEKRN
                     Y"
ORIGIN
        1 aagcacataa ctgtgcagac ctaagttaca ggcgtatccg ccgatattca gtctgacgcc
       61 taaagcgtct ggaagcacgt gactttagcc atgtgaggtt cacgattatc ggaaaatgcc
      121 tgtaaacagc gtaaatacag catttcaagg agttttaagc aatgataaga gtgttatttg
      181 tctgccacgg caatgtttaa tggatgccgt gaaagccttg attttattgg atttcttggg
      241 aattaaccaa taatttacac cttatttata cctttggaag accggatcgg aataatataa
      301 taaaatttgc taatttgtgt tgattttttt tatgattgag tataataaaa tcaagaacag
      361 aaatgttctc gatgtaagag catcgttaaa agttgggctg cagatggagc agggtaaact
      421 tccatctcat tagatgtctt aactgggcat cgagcctggt agcttggata aagctgtagt
      481 ccacgtgggg gacttaatga ttttcacgtc gttatgggta tcttaactgg gtatcgaggc
      541 tgacaaccag cagaaaactc ttttacaaaa gtaattctca gaagagtgtg gtttaatgcc
      601 acactctttt ttgcatgtga ggtataagtg gcaacaaagg tagataagaa aaacgcaata
      661 cgacaaggta ttacagaggc gtaaatcgta tatttccaaa atttggcagg taaaacattt
      721 ctgtatgttt gtggagatga atattttgaa gtttcttttc caatagatca ctttctacat
      781 ttaacaggag tggagacaag actttcgacc aaggattttt ataagaatgc aaaaaaatct
      841 attcttacaa ataatcagtt ctattttgac gcaagacatg tatatgcaaa tgccaaaagg
      901 aaacttccgt gtttaaaacg cttgccggaa ttaacgaatg aaatggtatg tgttctaaaa
      961 aatatggaaa ccatgacaat tacatataaa ctcagcgtta caaatttgga atttacagga
     1021 agtgtgacaa gaaagccaaa acggtatact gggaaaaaag attaagaaaa gaataaagag
     1081 ctggttttaa ttgtaaaatt tatggggaac taacatcagc ttattgacat gaatttaaaa
     1141 ataagtataa taatagttga gtaattgttc aactattatt atttggaggt gaatatatgc
     1201 caaaaacgtc ttatatttgt aattgcgatg taattcatga ggatattgtg aatgatgtga
     1261 aatccaagat gcagccaaaa gatgattata tccagttggc ttctttgttt aagctatttg
     1321 gagatggaac tagagtacaa atcttacacg ctctagaaca gagtgagatg tgtgtatgtg
     1381 atcttgcagt gctactgggg gtaacaaaat ctgcaatttc gcatcagtta aaggcattac
     1441 gccttgcgaa tctggtaaaa ttccgtaaag aagcacagat agtttactac tcactggcag
     1501 atgatcatgt gaaagagatt attgacaagg gatttgagca tctttggcag aaataatatt
     1561 ttttaacatt atagttgagt aattgaacaa ttaaacaaat tataaggaga ttatcatgaa
     1621 acgcatattt ctattaaaag ggttggactg tccaaattgt tccgcaaaaa ttgaaaaaga
     1681 agtcggagag ttggatggag tgcaatcctc agtggtaaat ctgatgaagc agacgattac
     1741 agtcaatgtt actcagacag ccgcagatac gatagccagt cagattgaaa cgattgttta
     1801 tagtcatgag ccagatgtgg aagttcagga agaaaccgtt atgaatgtta caaagagtta
     1861 ttcgttaaaa gggttggact gtccgaattg ttccgcaaaa attgaaaaag aagtcggaga
     1921 gttggatgga gtgcaatcct cagtggtaaa tctgatgaag cagacgctta caatcaatgt
     1981 tgctcagaca gccgcagata cgatagccag tcagattgaa acgattgttc atagccatga
     2041 gccagatgtg gaagtttctg aaattgtaca ggaatcttat ataccggaaa aaaagcagga
     2101 ggccaatgaa tcctataaca atgaggataa gaagttgaca gttcgtttag cgactggtgc
     2161 agcaatctat gccattggta tggcattgac tgtttttgcg aaagtgccac tgcctatcga
     2221 gttagctttt ctcattgttt cttatgttat tcttggtgga gatgttgtat ggcaggctgt
     2281 gaggaacatt tcaaaggggc gtgtatttga tgaacatttt ttgatgagtg tttctacgat
     2341 tggggctttt gttattggtg aatatccaga agcagttgct gttatgctat tctatcaggt
     2401 aggtgaattt tttcagtcat tggctgttaa gcgttccaga aaatctatat cagacttaat
     2461 ggatatacgt ccagattctg ctacagtaag aagaaatggg gaattgatta ccatatctcc
     2521 agaaaatgtc tccattggtg agattattat tgtaaagcct ggtgaaaaaa ttccattaga
     2581 cggtgtggta ttggatggag attctatgtt ggatacaagg gccttaacag gagaatcagt
     2641 tccgagaagt gttcataaag gagacgaagc actttccggt tgtatgaatc aaacgggtgt
     2701 cttaatgatt aagacaacaa aagcatttgg tgaatctacg gcttcaaaga ttattgatct
     2761 ggtggaaaat gcgtcaagcc gaaaagcacc aacagaaaat tttattacta catttgcacg
     2821 ttattataca cctgtggttg taatcttagc agcttttctg gcgattctgc caccgatcat
     2881 tcttggcgga ggctggacag agtggattcg cagaggattt gttttccttg tggtatcttg
     2941 tccatgtgca ttggttattt caatcccgct gactttcttc ggcggcattg gtgcagcatc
     3001 taaacgaggt gttcttgtaa aaggaagcaa ttatttagag gcacttaata atgtcagcgt
     3061 tattgtgttc gataaaaccg gaacacttac aaaaggtgtt ttcaatgtga cggatatttt
     3121 acctgcaaat ggattttcaa aagaacaggt tctggagtat gcggcagagg cagagagttt
     3181 ttctaaccat cctattgcaa aatccattct tgctgcttat gaaaaagaaa ttgatcagtc
     3241 agtgatttct gattataagg aaatttcagg atatggaatc agtgtaatgg caggggaaaa
     3301 gaaagttttt gctggcaata cgaaacttat ggatacagaa tgtatagagt acacaacctg
     3361 tgaaaaagca ggtacaaaag tttatttggc tgtagatggt caatatgcag gatgtatttt
     3421 gataacagat gaagtgaagc cggacagtaa aaaagcaatt tctgacctga aacatatcgg
     3481 cgtggaaaaa acagtcatgc ttaccggtga tgatgaaaaa attgggaagt ctgttgcaga
     3541 agaattgcag ttggataaat attatgcaca gctgcttcct gaccaaaaag tggaaaaggt
     3601 tgagctttta gatagtaaaa agagaccggg aagcaaattg gcttttgttg gtgatggtat
     3661 caatgacgct cctgtccttg cccgtgcaga tgttggtatt gcaatgggtg ggcttggttc
     3721 ggatgcggcc attgaagcag cagatgtagt tctgatgaca gatgaaccgt ctaagctggt
     3781 ggacgcgatt gaagtagcaa aagcgacaaa acagattgtc atgcagaata tagtgattgc
     3841 tcttgggatt aagagtgtgt tcctgattct tggcgctctt ggtattgcgg gaatgtggga
     3901 agctgtattt ggtgatgtag gcgttaccat aattgctgtt ttgaacgcaa tgagaatttt
     3961 gaaaaaatag gaaatgaggt ggaaatgtga aacgaaaact gattctgtta gttgttacga
     4021 ttgtttttct tgtaggtttt ggtgtcattt tacattcacc gccttctatg attgatgcag
     4081 tcacaggagc aacaccgaag tcaaaaaagg cggctcaagc ctccgcacag ttggaaggct
     4141 cttatgttct cggtattaat atgatgtcag atggtctcga caacgagaac acccggaata
     4201 aattaaaaga attggcactg gacgattcgg aaacaaatga aacagatctc atgaaaacgg
     4261 acattagttt tcggttatat gtatctgaga cggattatcc gcttgtcagt tatgctaaga
     4321 aactctgtga caggttgaaa caggccggtt tttccgtaga tctgaaagag tacagtaaca
     4381 caatgatgct atcaagagtg gtaagtggaa agtatgatgt attcctggca tcggatgatt
     4441 ttattgacgt tacaacgcta acacagatgg actatatgat catggacagc gaagaaatga
     4501 ggtgagcggg aatttatgag aaaatggaat acgattttgt ctgttttaat gcttctcatt
     4561 tttatgattc atggaatcat gggcagcttt atgctgaacg gagttggaag tagtgcaggg
     4621 aaacttcttg catggattgg tgttggcatt cttgttgtgc atacggtgat tggtgtcatc
     4681 ctgacagttc agagtttaca gacagcgaag caatcaggaa aaatgtatct gaaacagaac
     4741 gccatatttt gggcgagacg agccagtggg atggcaatac tgattctgct gttattccat
     4801 attggcttgt ttggaaaggt gcagaatggg acatatattt tgttcccttt tacaacggta
     4861 aagatggtaa ctcagctttt gttcgtagcg gcaatctttg ttcatatttt tatcaatata
     4921 cgcccattgc tcgtatcact gggaatcatt agttataaag aacgaaggag cgatatttat
     4981 ttgatccttt cggtgcttct tctttttata gcgggagcgg ttattttata ttatattggg
     5041 tggcaatatc tatgagtaag acaattatta ttataggtgc tggactggca ggactttcag
     5101 cggctttgca ggcagcggaa aatggatgca atgtaaaact ggtttcctcc cttccgtcag
     5161 agcgggcaca gtctgttatg gcggagggcg gtatcaacac agctttgaat acaaaagatg
     5221 aaaacgacag tcccgaagaa cattttacag atacaataaa ggcagcatgt ggtctggcag
     5281 atccaaatgc agtttgggga atgacacagg cagcaccgga gctggtgcac tggctgctaa
     5341 aacttggagt taaatttaac atgagtggct atgatgatgt ggatctgcgg aattttggcg
     5401 ggcagaaaaa gaaacggact gcttttgcac agagcgatac cgggaagcag atcatgacag
     5461 ctatgataga cgctgttcgc aggaaagaag catctggtat ggtagaacgg ttcagccatc
     5521 attctttcct aacacttcgt ctgtgtggca atatttgttg tggctgcgta atcagggatg
     5581 aatacagtca ggagactgtg gaattaccgg gggatgcggt tattgttgcc accggtggta
     5641 tgcacggatt gtttggaaat acaacgggtt cgctgagcaa tacaggagaa gtcaccgcag
     5701 aattgttccg gcttggtgtt cctctggcaa atagcgagat gatccagtac catccgacaa
     5761 ctgtgaaatg tggtggaaaa cgcatgctca tcagcgaggc ggccagaggg gaaggtggca
     5821 ggttgtttgc catgaaagat ggaaaacaat ggtatttcat ggaggaaaaa tacccggagc
     5881 ttggaaatct gatgccacga gatattaccg ccagagagat atggaaggtc agccatgaat
     5941 cagaggtatt tcttgacatg acggaaatat cggaggagat tatttcaaat aagctatctg
     6001 gtctggcaga cgattgtatg acctatctgc ataaagatat acgaaaggaa ccggtgtctg
     6061 ttttaccggg aattcactat tttatgggag gcattctggt ggatgagcag cacagaacgc
     6121 cgattcagaa tctttacgct gccggagaat gctgtgccca atatcatggt gccaaccgtc
     6181 ttggtggaaa ttctctgtta ggagcgttat acggaggacg tgttgcggca aaatcagcac
     6241 gtgaacaggc agatgtagta gatctatctt gtgcgacaca gatagatttt ccaccaacgt
     6301 ctcaaatttc agaaataaag caattaaaca aagtgatgca ggatactatg ggcgttgtca
     6361 gaaatgagaa tacgttgtta aatgggattc aaacggtaca agcgctgaca ggaaatcttc
     6421 cattgcttgg catggcagtt ctaaagagtg ctcttgcaag aaaagaaagc cgtggtgcac
     6481 actggcggga ggattatccg aagagcaatg acgatgatta ccttaaaaca acggtagcca
     6541 gatttgatgg aaagcagata cagatttcct ttgtacctgt tccagaaagg cggtgattca
     6601 cttggtatat aaaataagaa tcaggcggca ggagagtcag aaatcagaca gttattggca
     6661 ggaatttgag tttgacggaa gcaaaaacag ctctgttgcc aatgttctaa aggaattgaa
     6721 cagtagaacc cctttgaaag ataattcagg gaatatagtt actcccatca gctgggaatg
     6781 tagctgtatg gtgcgaaaat gtggggcttg cgccatgctg attaacgaac gtccgaggct
     6841 ggcatgctct acatttctac atacgttaaa aggttctaca atcaccttgg aacctttaag
     6901 caaatttccg cttgtaagag atttgatcgt tgaccggtca attctgtttg aaaatttgaa
     6961 aaaactgaac ctttggcttg aaagtgaagc ttatatgaat cggtggacac atgaaccgag
     7021 ataccagtcg gcacgctgtc taatgtgtgg ctgctgcctt gaagtgtgtc ctaacttctc
     7081 tgcaaatggg actttcgcag gcgctgttgc tgcagtcaac gcatttcgga ttctgaatga
     7141 agaacaggaa agcactcatt tgaatgagat ttctgctgaa tataagaaga aatattttga
     7201 gggatgcggg aagtcgttat cttgtcatga tatttgtccg attggtctgc ctctggaaga
     7261 actgcttgta aggtcgaatg cagcggctgt ttggggcaaa taaaatggat gataaaagct
     7321 ataatgaatg tatgaagaga atcaaaaact taagacatgg atcacaccgg atcttgcgac
     7381 ggagtatctc gcaggagccg tgcttctcgg agcagctcca tgtaccgcta tggtatttgt
     7441 ctggagtacg ctgacaaagg gaaatccagc ttatacagta gttcaggtgg catcaaatga
     7501 cattattata ttatttgcat ttgtaccgat tgtgaaattt ctgcttggtg tttctaatgt
     7561 tagtgttccg tttcagacgt tatttatgag tgtggttcta tttgtagtaa taccacttgt
     7621 agccggaatc ataacaaggc tgctggtagt cagaaagaaa ggtacggaat actttgagca
     7681 gacttttctg cataaatttg attccgcaac aacagtggga cttttgctca cgctgatact
     7741 gatttttatg tttcagggcg aggtggtgct ggacaatcca ctgcacatta tattgattgc
     7801 agttccgctg atcattcaga cattctttat attctctctg gcatttggag tatgcagaat
     7861 tatcagactt ccgtatgata ttgcagcccc ggctggaatg attggtgcat cgaatttctt
     7921 tgagctagct gttgcagtcg ctgtagcttt atttggtaca tcaagtccag cggcactggc
     7981 aactacagta ggtgtattaa cagaagtccc ggtaatgctt actcttgtga agattgcaaa
     8041 caaattaaag gagaagttca agtatgaata agaaaaaagt tgcttttata tgcgttcata
     8101 attcatgcag aagccagatt gcagaagctt tgggaaaaca tctggcttcg gatgtatttg
     8161 aaagttattc ggcagggaca gaaacgaaac tacagattaa tcaggatgca gtccggatta
     8221 tgaaagaatt gtatggaatt gatatggaag cagaaggaca atatagtaag ctgattgatg
     8281 agataccagt accggatatt gcaatttcaa tgggttgtaa tgtgggatgt ccgtttatcg
     8341 aaagaccgtt tgatgacaat tggggacttg aagatccaac cggaaagagt gacgaagagt
     8401 ttaagaaggt tattgatgag ataaggatgc aaatttttat attgaaacaa cgattggatg
     8461 aatttgaaga aaactaaaga agttgagaaa ttccagttga tatttcacat attttaggaa
     8521 atttaataac tgttatattt gattatcaaa ttcttcgcaa acccttgaaa atactaagtt
     8581 tgtagcaagt gtacttcccc ttactctttc ccttgtgtta cattctccca ttagctttca
     8641 tgaaccttaa tatgggaaaa attaagggaa agaaaatttc ataacacagt ataacatata
     8701 acaataacga catggtgaac tgattgaaat gttttcgata tttaactcta taactgatta
     8761 tcaaaagaaa atggagataa gatacgatga gaacaattta tgcagaatac aacataaatc
     8821 acgatagtat tgatgtttac acaagtgctg gatatatgct tcgcattgac tgctgggaag
     8881 ctgaaaaaga tttaaaaacc acatatggat cagaatgtgc acttacttca ttagctgtgg
     8941 atgagccttt ggaatatgca agattatatc ttgagggcaa tttacagatg tgggtggatg
     9001 cagaagattc attagaactt tattaagtga aagagggata gtgttcatta agagtgctat
     9061 ccctctttaa agaatgtgcg aaatgcaata attacatatt ttctatggat taacagagcg
     9121 cctaaaaata atccatgtac ttatgaagta acaaatcaat aaaattgcca aaatccccat
     9181 tgttgcccct atttgtaaca tcaatgtact aaacccaata taggctgaaa tttctgctga
     9241 tatggtttgg ataaagtaag ctattacaac agcagctaca atgattgctg tgataattgg
     9301 cagcccgaac caaatactta attgcttcaa gataagcttt cctatatgct tttcctctac
     9361 acctaatttt cggagtacag agaaacgata cttatattgt cctgcgtcta aaagctgttg
     9421 cagggaaagt accgtaagac atataaccat cagtacgaca gcaccataaa tcattgacgt
     9481 ctgtaaaata aagttatttg ctatggaact attgatttgc agtgtgctaa aacgcacgcc
     9541 ataaatagcc ccggtttctg cctgctcggg atacttctct gtaaaaagtt tttccagttt
     9601 ccttgcattt tcataggaga tattttccgt tgttgtaata tatcggtttt ttatcactgg
     9661 caacagcttt tcacaaatat tgtctggaag tacatacaat acatttgtat aggaattgta
     9721 cgctgtttct ccaatcggat cctcataata ggactgcccg gaaagagtca attctcctgc
     9781 gtctgtcata atgctggcgt gttctttcaa aaagttatcc cgttcttcct cggtggcgat
     9841 tgctttccat tgtgttgtaa attcatcttc ctccagagaa atctgttcgt aacccagcat
     9901 ttcccgtata gtgttataat cactcaaaga aattgctaca atcggaaaat catatttctg
     9961 tctgttgtga aaatcgtctt tctctgacag atatagattg aacgtgcaat cataaactgt
    10021 atctattttg tgttctgtca gaaaatcagt aatgatttca taactgtctt gcggcagatt
    10081 ttcctcttca tatacgtcat tatatcttga atatacctgc acatcataca tagagcgcat
    10141 atccaaataa cctgaagccc agcccgtcaa aataggggcg gcaataaaca tgaagattgc
    10201 aaggacaagg gttatacaaa tcagcgtcat tgttttgctg gttgtattta gttttgatat
    10261 aatttgcccg aaaaagaaca ggttttctcc cttgtatcta tgttccggcg attttccttt
    10321 ccatgctaca atcaaaccac tggtaagata aatgaaggca caaatgaaga aaagtaagtc
    10381 aatcacaaca aaaagcagat attgattgag cgttccacca cctaaagaca gataatattt
    10441 atttgttaat gctgcaacgc tggctgctgt aaaagcattc aatacagaac atatcagcaa
    10501 accagcaatg aaacattctc tttttttctt tctaattatg caaaatatcg accacagcaa
    10561 agtaagcagc ggaaaaagaa tatttcccca aaacataagc tgcaccggaa acgcaaagcg
    10621 ggtgtcataa taaaaccaga ccttttgtat tcctgtcatc aatccccata cggtaaatac
    10681 ttcaaagagg actactacaa cagaaatgaa gcggctcttt tttagctctg gttcgttctc
    10741 tttctctgcg gaaagcatat caataatttt tgttttctga atggtacggg tattgaaaat
    10801 tcctaccaca aaaaaacttg ccacaaaaaa taccactgtc aacaaaacgg tatccgggaa
    10861 taatgtccat gagatttcat aaggctttcc ataagcagta aggagcattg cggtaatgaa
    10921 ttgagagcaa aatacaccgc aaaaaatacc aatcaaaatg gaaaacatac ccataatcag
    10981 tgtttctgca aagaaaatcc tgccaatggt tttttgttcc attcccataa tggactggac
    11041 agcaaactct ttttgcttcc gtcttagcat ataatgattg acgaaccgta ttaaaaatag
    11101 caatagcaag gttatcatgc agattgcaat tttcattccg tcacttaaca gcgtaaaatc
    11161 atactcgctg cctatatccg ggctataata actactggaa atagacaaga acgcataaaa
    11221 caaggtaaca cagattgtca ttgtgacaat gtagaccaga tagtctttta cagacctctt
    11281 tgcatttctg aaaacaagtt tagcatacat ggctctgtcc ccctccgatc atggtaagga
    11341 cattcagaat tttatcaaaa aaatcacttc tgctgtcgtt gcccttgcgc agttccataa
    11401 agatttctcc gtctttcaaa aaaagaatac ggctggcata gctggcggta aaagcgtcat
    11461 gggttaccat aagaattgtc gccctaagct gttcattgat actttgaatg gtagacagca
    11521 gcatttgtga ggaatggctg tctaatgctc ctgttggctc atctgccagt aagagtttcg
    11581 gattgttgat aattgctctt gcacaggcac aacgctgttt ttgaccgccc gatacctgat
    11641 aaggatattt gtttagaata tcgctgatat tcagctttcc ggctatatcc aaaatgcggg
    11701 gttctacgct cccggcaggg actttgttga ttgctaatgc cagtgcaatg ttttctgaaa
    11761 ttgtcaatgt atccagcaaa ttgaagtctt gaaatacaaa acctaaattc tctctgcgaa
    11821 agcgggcaag ggattttggg ttgatttccg ttatatctgt tccctctaaa aaaatatgcc
    11881 ctgcacttac ggtatcaatc gtagaaatac agtttagcag cgttgtcttt ccagaaccgg
    11941 acgcacccat aattccgaga aattctccgg cttccacaga aaaactaata tctttaatgg
    12001 ctttggtaat attcccctca ttgccataat atttctggat atgctccagc ttcaaaatcg
    12061 tattcatctg ataaacctcc ttaactgttc catatcttta ttgtaaatgg agtatctcat
    12121 tttttgtatc aagttttctt acacagttct tacaaaaatg taagaagtgc agaacctgtc
    12181 agccctgcac tccgataata aaatcattca tttgaaagat aagtgaaatc gttgttcctc
    12241 tgttttcgga ataagcagta agccctattc ccagtttatc acatagacgc ttgcaaagat
    12301 ataagccaat tccagtagaa tttttcccgg ttcgcccatt ctgacctgta aatccttttt
    12361 caaaaatacg gggtaaatca cttttaggaa tacctatccc attatcgctg atagatagca
    12421 caatcttgtc attcgttttt gttgccctaa agtgcaaaat aggctgctct gcatggtatt
    12481 tgattgcatt accgataatc tgatttaaga tgaaccgcac ccatttttca tcggtataaa
    12541 cttttgtttc tatatcgtct atctgaattg acatattgct ttgacgcaaa agatacttat
    12601 tatctgcgat tgcactatgc acaacatcgc ataaattgac ttcacggaca gaatagtctt
    12661 tttcagcgtg ttcactccgg gcatagtaaa gtgcctgttc tgtatattgg ttgatattct
    12721 ctaactctgc caatacctct ctggaaaagg gagaacggtt attctcacac agcagcttca
    12781 tcgctgtaat tggtgttttt acttcgtgta tccattgttc aatgtattct ttatattccc
    12841 tgcgttccct ctgtacttcg ccaatccgtt ccaacataga tttttcagcc attttcataa
    12901 tctggtaaaa aacctgttca tcagcccttt ccggcacttg catgatttcc ggcaataaat
    12961 atcgttcttc taattgctcc gtcatattga gcaatttatt cagatatttt tttcgtgaga
    13021 aataaaatgc cagcaaagat aaaacaagga caatcgacca gactgcaaaa ataaacagga
    13081 ctgtttggat aggattatcg cttgcaatca ggaacaaagc aaggacaagc atacccagca
    13141 gattgattaa aataacgggg agttgatttt tcaaatattg ttttccactc ataatgtata
    13201 tccttgcctg tgttttgttt taatgaaatc tacaagtccg attgctgcca gtttgtcgcg
    13261 aatacgggta atattgacac ttagggcgtt atcatcaaca taaagctgat tgtcccaaag
    13321 aaaatccaca atatcatttc tggaacagat ttttccggag ttcttaaaaa ggtagtagag
    13381 gattttcaat tcattctttg tcaattctgc tttctgtcct ttgtactcta tcatgctact
    13441 ctccaaatgc agggtagctt ctctccacat ataaatttct gtttgagggg aacggtaggc
    13501 tttctttaac aatgcagcaa ttttagcaag aagaatagcg ggattataag gctttgtgat
    13561 aaacgcatct ccacccagca taatgctgtt cagttcgtcc atatctgtat tgctgcttgt
    13621 tacaaataca atcggaatat ctgaaaaggt gcgaatcccc gagcatattt caaaaccgtt
    13681 attccccgga agttttatat ccagaataac cagatgtggc gcagcttctt ttaactgctc
    13741 tattgttttg gaaaaatccg taactgcaaa tacttcatat ccattcccag acaaaagagt
    13801 tttaagctgt gtttgtatcg taaaatcatc ttcaatgatt agtatttttt ccttcataga
    13861 gatacctccc tgacacttta ttatactgta tcagagaggt tttctcaatc gtattattga
    13921 atgggaattt tagaatgatt ttgtacatag ctttgtaaaa aatgcttaat agtttctttt
    13981 ctcaaggtac gattctaaat aacacctaag tccaacatat gcgccctgca aaagtacaaa
    14041 aagcaataga agatttactg acagtgcttt tttgattgct tctccaaaat aaatgatgac
    14101 agcagcactt gtcagtatca tcagtagagt aatgacatcc caacactttt ccctatataa
    14161 ttctataacc tttatttcta tcagtatcgc cagtatccct gttcctgcca cacatattcc
    14221 tacaatcaat attagcaata tccaatatac cattccggct ataaaaggat ttggaatttt
    14281 tgtgctaatc tgtgccacag attgcccgac ctcaatcgtc caaccgataa aagtttgtat
    14341 gaatgacgct gcatcatgga agaatgattt gcaatcggaa aggagcacat ctgactgtac
    14401 tgcctgaaaa agagtggttg tcagcgaata ccatgcaaga aggaacaagg ttgtttggaa
    14461 ca
//
