LOCUS       c00022_gnlPro..        13663 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DOMKMGBC_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:34:44
            Original ID  :: gnl|Prokka|DOMKMGBC_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13663
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13663
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[192:3663]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      193..3663
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13663
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13663
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(193..948)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_1"
                     /sec_met_domain="Fer2_3 (E-value: 3.4e-25, bitscore: 82.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.8e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.3e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDISVTLKVWRQRGPKEKGQFETYKIEKINQSVSFLEMLDILN
                     EQLVNEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFHDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKKDADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(979..2922)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 193.2; E-value:
                     2.7e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.4e-58, bitscore:
                     193.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.6e-37,
                     bitscore: 122.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKVERYAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDNPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAIKDRIQKLMNIKGKETVDTIHRKLGHI
                     MWEHIGMARDAKGLQEAIQMLKDLKKEFWSNVFIPGNADNLNTELEKALRVADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     EFVVPQTRNYKK"
     CDS             complement(2971..3663)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="SucD_FumR (E-value: 3.1e-73, bitscore:
                     239.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAV
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             3786..5264
                     /locus_tag="ctg22_4"
                     /transl_table=11
                     /translation="MGEVRACAPTHEIMRKEKVFLMNNLYTFAYMRKDLNGARHFSIGI
                     KFTILLFTIAILVLVLFSYRSDKHGNLFWQVEKLIPHHPDSALVLLEKVTDINGLSLRE
                     KARYCLLWTESRDEAGLRHTSDSIISIATDYYRTTRGCYWPPKGWFYRGKVYEDMDQPS
                     LALECYLRALEYEGGNWDYEFWGRLYNQIGRLYAEQELYGKAMSFLRKASAQYQLLNDT
                     AGQGRILEEVKKYEALRDSIGSLSARESIYQITSRYDVRPVREDLYRKELMLSQRGQER
                     YLYAFIIGIILFICFFLYRRWRNTQENALRREEALRRSIASQQQRMREEKEENERQIAL
                     LEKKITKIKEEKDQELMLVSLQLEKQRLEICNESIHNKESKHLLSVAILRKSEVYEKLH
                     DRDAGKIVSEDWELLEVLLNKAYDDFTLRLKKLYPAISDTELKVCMLTKIGVPANQITR
                     VLKYNSSVLRPRLFRKIFKKEGSTETFVEFISSF"
     CDS             5374..6597
                     /locus_tag="ctg22_5"
                     /transl_table=11
                     /translation="MKSVKLASVLFYLNSVFVVSCFVSCGSSPTEASSLLTADIRGGMD
                     EPGLLGLGDEIKGAIFVPLEVTTDDASLIDGVYDYAVTDRYIYVLPVKEPRIVLFDRQG
                     RFIRTLVKEGQGPGEFSGILPCIQVDERNDRLFLFSNNRVWEYTLEGEFIGQSTHEYSV
                     IYMRHIGKERFAAISFPFQPFNGGGFGLGLFSRKGDTIAIKNDFYSFLLPHEKSGFTTS
                     IAPAYSDAQNSVLFKTGSNDTVFCISADRISAACVLDLKNSDAEVIRSLDVTDMSNLRI
                     EKKDPKDIFVQDMIEFPEHYYFRLLYNQGYYIASVDKKTGKTLVEKCEMPGSIYELADA
                     NLQHGMQGTRSYRNFPVWGRVIKDELVQVVTPYELNLYKSLRSITIPQELDLKGEEGNP
                     FFVFYSLI"
     CDS             6826..7317
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="MKKAIMNTMIILFALAMCVGCGQSSEQKEESVPTDVTKAEKQEQV
                     QVVAEDEDTLENGEQVFRVVEVMPKFPGGDAELLKFIAKNVKYPQESQEKGEQGRVICS
                     FVVTKDGTLTNYKVLRGISPALDQEAVRVLRMMPRWTPGTQRGEPVAVKFTVPITFKLQ
                     "
     CDS             7432..7794
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MEKLTMQEEEAMRWIWRIGPCFVKDVLAKYEDPKPPYTTLASVIK
                     NLERKKYVKAKRYGNTYEYRPLIEETEYKRTFLGGVVTNYFANSYKEMVSFFAKDQKIS
                     TDDLKDIIDLIEKGKE"
     CDS             7812..9437
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="MTPEFAYLLKVNVAFVLFYAFYRLFFYKDTFFKLRRAILLAFFGL
                     ALFYPLLNIQDWVRQQEPIADVIYMYSAMLPEATAKADAAASVDWYGWLLGSLGFIYWG
                     IVAFLCGRFLVQLSSILWLAHTSERVVIHKTPVYALRKAAGPFSFFRMVFLHPESHSDK
                     ETDEILTHECTHVSQWHSIDVILSEMMCMACWFNPFVWLLKREVRHNLEYLADNTVIQS
                     GYDSKSYQYHLLGLAHHQSVTTLYNSFNVLHLKNRIMMMNKKRSPGIVRTKYLIFIPLV
                     GILMLLSNIEAVARLTVRLANEATVSNAMVTATDVSSKSREMNEQVFTVVEKMPSFPGG
                     DEELLKYIATNIKYPKESQDNGEQGRVICSFIVGRDGSVNNPEVLRGVTPLLNEEAVRV
                     INTMPRWNPGMQRGKAVAVKYTVPITFRLKSPVEETKEETLTVVDVMPQYPGGDRELLK
                     FIAQSIKYPTDAQEAGVQGRVICSFVVDKKGNIVEPKIIRGIDPSLDAEALRVIGMMPR
                     WTPGRQDGKAVRVLYTVPITFRLQ"
     CDS             9494..11356
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MNAKCNLVTVLLLCCLIFPGNAQEFNWQDLVNRKQYAAVIARADS
                     LTPADSSDYEVMNAIGQAYEGMLRYRQAYDYYRLCLSMDTTNLDILNTLARTATNLGKA
                     KDAERYFHKVLAADSLNFYANYQLARLYFQLGEYERAVDTYEKLQARNEDNTALYRAIG
                     DCYSRLEQYPSATIAYFQAYNLNRENAGLAGALVNTLYRMGVGSPDYILEGVAICDTAL
                     IYNPGNRQLLRSKALGLYMAKQFAQADSIYSGLLADGDSTYLTLKYGGASKYYAGLYMP
                     SVDILDMAYEQDTTSVEVCLLLGSALGKTYDRKRAYDLFDRAEKGLEPNRFLVNQLLAF
                     RAETYQKDGRYKEASRLYYEAWKKNPERLDFLAAISHMYSEIDVSKFQSEEDRQRGLFI
                     LVLYMNESLKKKADERTMVFSRALLQSFYEDMFFRNVVEETMIDPDGKKSKISIVDLRN
                     LINQLPEESEMVMEIRAMSARSSGKIEEAARLLYRAWKVKGTRVELLREIANLYSHPDI
                     SGFKNAEELQRGVFAQVTYAKELLKNELDLSNLTFTRPFLESLNSDMSKRGITEQTMLA
                     PDNRKSQLSIDELQSLIQQLPETSDEVKEMIRMMNKEKALKSKK"
     CDS             11488..12138
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="LICYKSYPSEKGKRECHLIISKQDGRITHEIQIPSKGTETPVVTE
                     GEFIITPEFYLTFPDGDKWILVNTSSDTIFHYLPDRNLSPFIVRSPSISSMDTKVFLFP
                     TVITDRYCFMRTMRKEIDFTTFKGFLGEDLVYDKQENALFSYILYNDDFINKEEVSLTS
                     EPRNPEIAICQTLDTPDLVEAYEKGQLKGKLKEIAANLSEESNPVVMLLKKKK"
ORIGIN
        1 gacaagccct aaccaaactt tgttaacctt aaatctaata ctattatgaa aaaaccacga
       61 tgcaaagata cggagttttc aattcctgtc aagatctgta gtgctaaatt atgtttttca
      121 acatataaca aaaataaaaa ggcgccttcc ttttagagaa agacgccttt tccatgatat
      181 actaatcaaa tattagtctt gtagcttagc gcagatgaac tcacggttca aacgagcgat
      241 gttactaacg gagatgttct tcggacactc catctcgcaa gcgcgtgtgt tcgtacagtt
      301 accgaagcca agttcatcca ttttagcgac cattgctttg gcacggcgag cagcctcgac
      361 tttaccttga ggtaacaaag ccaactggct cactttggcg gatacgaaca acatagctga
      421 accattctta caagcggcag cacaagcacc acaaccgata caagcggcag catccatggc
      481 taagtctgcg tctttcttgg ggataggtat tgcgttagca tcgggtacac caccagtgtt
      541 gacagatgtg aaaccaccag cttggatgat tttgtcgtaa gcgtagcggt ctaccatcaa
      601 gtcgcggata accggaaaac ctgcggaacg ccacggctcg atcgtaattg tttctccatc
      661 gtggaaacgg cgcatatata actggcaagt cgtagctccg gttgccggtc cgtgtgggtg
      721 tccgtttaca tacaatgaac acataccaca gataccctca cggcagtcat gatcgaatac
      781 gatcggttcc ttaccttcgt tgaccaattg ctcgttcaag atatccaaca tttccaagaa
      841 agagacactt tgattgatct tctcaatttt gtatgtctcg aattgtcctt tctccttcgg
      901 acctctctga cgccaaacct taagtgttac acttatatct ttatccatga ttctaatttt
      961 ttctgcgatt gatgattatt acttcttgta gttacgtgtt tgaggaacaa cgaactcgta
     1021 gttcaaatcc tctttcaaca tgacaggatc tttgtcctcg ccttggtact cccagcaaga
     1081 tacgtacatg aacttatcgt catgacgtaa ggcctcacct tcttctgtct ggtgctccgt
     1141 acggaagtga ccaccacaag actcggcacg gtccaaagca tcgtgtgcca tcaatgtacc
     1201 aatctcgata aaatcggcta cacgtaatgc tttctccagc tcagtattca agttgtccgc
     1261 attgcccggg atgaatacat tgctccagaa ctctttcttc aagtctttca gcatctggat
     1321 agcttcttgc aaaccttttg cgtcacgtgc cataccaata tgttcccaca tgatatgacc
     1381 tagtttgcgg tggatcgtgt ctacggtttc tttacctttg atattcatca atttttggat
     1441 acgatccttg atggcctttt ctgcctcaac gaactccggc agatcagtac tgaagcgcgg
     1501 aacttggatt tggtcagaca aatagttctg gatcgtgtat ggtaatacga aataaccatc
     1561 ggccaatccc tgcatcaaag cagaagcacc caaacggttc gctccgtgat cggagaagtt
     1621 tgcctcacca atagcaaaca gacccggaat ggaagtcatc aactcatagt caacccataa
     1681 tccacccatt gagtagtgta atgcagggta gatcatcatc ggagtctcgt atggattatc
     1741 attcgtaatc tcttcgtaca tatcgaacaa gttaccgtat ttctgcttaa cgacttcttt
     1801 acctaaacga ttgatcgcat cggagaaatc caagaatacg gccaagcccg tgctgttcac
     1861 gccgaagcct gcgtcgcaac gttctttagc ggcacgagaa gccacgtcgc gaggaaccaa
     1921 gtttccgaat gccggataac gacgctccaa ataataatcg cggtctgcct caggaatatc
     1981 tttacctttc ttcgttccgg cctgtaaagc tttagcgtct tccagtttct tcggaaccca
     2041 gatacggccg tcgttacgca aggactcgga catcaaagtc aatttagatt ggaagtcacc
     2101 tttcactggt acgcaagtcg ggtggatctg gaccatacaa ggattagcga agtaagcgcc
     2161 tttcttgtag cattgccatg cggcggaacc gttagatgcc atagcgttgg ttgacaagaa
     2221 gaacgtatta acgtaaccgc ctgtagccac aactacagcg tgagcggcgt aacgctcgac
     2281 cttacctgta atcaagttac gggcgatgat accacgagca cgaccgtcta ccttaactac
     2341 atccaacatc tcatgacgag tgtacatctt aaccttaccc aaaccgatct gacggctcaa
     2401 cgctgaataa gcacctaaca aaagctgctg acccgtctgg ccacgggcgt agaacgtacg
     2461 cgatacctga gcgccaccga atgaacggtt atccaacaaa ccaccatatt cgcgagcgaa
     2521 aggaacgcct tgagccacgc actggtcgat gattgagtta gaaacctctg ccaaacgata
     2581 aacgttagcc tcacgagcac ggtagtcacc acctttgatc gtatcgtaga acaaacggta
     2641 aacagagtca ccatcattct ggtagttctt agcggcgttg ataccacctt gagcggcaat
     2701 agagtgcgca cggcggggag aatcttggat acagaagttc aatacgttga atcccatctc
     2761 tgccaaagat gcggcagcgg aagctccagc caaacctgta ccgactacga taacatccaa
     2821 acgacgcttg ttagcggggt tcaccaattt ctggtgattt ttataattag tccacttctc
     2881 agccaacggg ccttgaggta ttttagaatt tatttcagac ataatgattt aatttcaaaa
     2941 gttcttaatt ataaaacctg tagcttgcaa ttaagcacct actccgttta ggaagaagat
     3001 gatagtaatg atcgcgaaaa gtccgcaaat aaccgtagct acgatcttag agatacattc
     3061 ccaacggttc atccagatcg tgttattcca accgattgtt tggatagcgc tccagaaacc
     3121 gtgagtcaag tggaaccaca aagccacgta ccagatcaaa taaagaacgg tgatcacggc
     3181 attaccttgg aagtaatagt tgataaaagc ggctccgtct tgtggagata ccatagctga
     3241 ccccaatgct acttcgtgat gaccgatcaa ttcggcgaac atcatcttat accagaactg
     3301 gctgaagtgc aacagcatga acaggataac gatcaaaccc aaaacgaaca tgttctgaga
     3361 tgcccattcc acgcctttcg gacgagcgtt gatagcgtaa cggtcgttac cacgtgcctt
     3421 acggttttgc aaggtaagaa tgatagcgta cacgaagtgg atcacaacgc ctgcggccaa
     3481 tacgagagta gctgccacag cgtaccaatt agagcccaac agcgaacaaa ccatgttata
     3541 agcctctccg gagaaaacgg cagccacgtt catcgacagg tggaacaata agaacaaaac
     3601 aaggaagaga cctgatatgc tcattatcag cttcttcccg atagaagaat taagtaacca
     3661 cataagataa taatttaagt tatttaattg tatttagaaa tttctactta aactatgtaa
     3721 ttatcacgca aaggtatgct aaatccatat atcgcgcaaa cgattaaaga aatatttctg
     3781 cattaatggg agaggtcagg gcatgtgccc cgacacatga aataatgcgg aaggaaaagg
     3841 ttttccttat gaataattta tatacatttg cctatatgcg taaggatttg aatggggcac
     3901 ggcatttttc catagggatc aagtttacga tcttattgtt tacgatcgcg atcttggttc
     3961 ttgtgctttt ttcatataga agcgacaagc atggcaacct gttctggcag gtagagaaat
     4021 tgattccgca tcatccggac agcgctttgg tgttattaga gaaagtgaca gatatcaatg
     4081 gattatcgct tcgagagaaa gcccgttatt gtctgttatg gaccgaatca cgggatgagg
     4141 cgggattgag gcatacatcg gattccataa tctctatcgc tacggattat tataggacga
     4201 cacgaggctg ttactggcct cccaaagggt ggttttaccg ggggaaagtc tatgaggata
     4261 tggatcaacc gtccctagct ttggaatgct atttacgtgc gttggaatat gagggaggga
     4321 attgggatta cgaattttgg ggacggttat ataaccagat agggaggctg tacgccgagc
     4381 aggaattata tggcaaggcc atgtcttttt tgagaaaagc gagtgcccaa tatcagctct
     4441 tgaatgatac ggccggacaa ggccggatac tggaggaagt caagaaatac gaggcgttac
     4501 gggattctat cggatcgctg tcagcgagag aatcgattta tcagatcact tcccgatatg
     4561 atgtaaggcc ggttcgtgag gacttgtata ggaaagaatt gatgctatcg caaaggggac
     4621 aggagcgtta tctgtacgcg tttattatcg gcataatcct atttatttgc ttcttccttt
     4681 atcggcggtg gagaaatacg caggaaaacg ctcttcgaag ggaagaagcc ttgcgacgct
     4741 cgattgctag ccagcaacaa cgtatgcgag aagaaaaaga agagaatgaa cggcaaatcg
     4801 cccttttgga aaagaaaatt acgaaaataa aggaagaaaa ggatcaagag ttgatgttgg
     4861 tttccttaca attggaaaaa caacggctgg agatttgtaa cgagtcgatt cataataagg
     4921 agagtaagca tttattatct gtcgcgatct tgcggaaatc ggaggtctat gagaagttgc
     4981 acgatcggga tgccggcaag attgtctctg aggattggga gcttttggag gtgctgttga
     5041 ataaggctta tgatgacttt accttacggc tgaaaaaact atatcctgct atttccgata
     5101 cggagttgaa ggtctgtatg cttacgaaga tcggcgttcc cgccaaccag atcacacggg
     5161 tattgaaata taatagttcg gtacttcgtc ctcgtctatt ccggaagatt tttaagaaag
     5221 aaggttctac ggagacattt gtggagttta tctcaagttt ttgattatta tatatttata
     5281 gcggtcttgg caggtttgtt ctcatttttg ttctcattta tcatgtgatt tgtgagatat
     5341 gcgggatatt tttggaggca aaaaagcatg gttatgaaaa gtgtaaagtt agcctctgtc
     5401 ttgttttatt taaatagtgt ttttgtcgtt tcttgtttcg tgtcatgcgg ttcttcgcca
     5461 acggaagcgt cctctctttt aaccgcggat ataagagggg ggatggatga accggggcta
     5521 ttgggattag gcgatgagat caaaggggct atttttgtcc ctttagaggt gaccacggat
     5581 gatgcctcgt tgatagacgg agtttatgat tatgctgtga cagatcgata tatctatgtg
     5641 cttcccgtaa aagagccccg tatcgtcctg ttcgatcggc aagggcgttt tatccggacg
     5701 ttggtaaaag aagggcaggg gccgggtgaa tttagcggta ttctgccatg tatccaagtg
     5761 gacgaacgta atgaccgcct ttttttattt agtaataatc gagtttggga atatacgttg
     5821 gaaggtgaat ttatcggaca atccacccat gagtattctg taatctatat gcgtcatatc
     5881 ggaaaggagc gtttcgccgc catatcattc ccttttcagc ctttcaacgg aggaggattc
     5941 ggattaggcc tattttcgag gaaaggggat acgatagcga tcaagaatga tttttattcc
     6001 tttttattac cccatgagaa gagcgggttc acgacaagta tcgcccccgc ttattctgat
     6061 gcgcaaaact ccgtgttgtt taagaccggt agtaatgata cggtcttctg tatctcggcg
     6121 gatcgaataa gtgcggcctg tgtccttgat ctgaaaaact cggatgcgga agtgattcgt
     6181 tcgttggatg ttacggacat gagtaatttg cgaattgaaa aaaaggaccc caaggatatc
     6241 tttgtgcaag atatgattga gtttccggaa cattattatt tccgtttatt gtataatcaa
     6301 ggctattata tcgcctctgt ggataaaaag acgggaaaga cactcgtgga aaaatgcgag
     6361 atgccgggtt ctatctatga actggcggac gcaaaccttc aacatggcat gcagggtacg
     6421 agaagttatc ggaatttccc ggtctggggg agggtcataa aagatgagct ggtacaagta
     6481 gtgaccccgt atgagctaaa cttatataag tcgcttcgct cgatcacgat tccgcaggag
     6541 ttagacttaa aaggagagga gggcaatccg ttttttgtgt tctattcgct tatctgactt
     6601 cgatatgtat cactcggttg tacttcttgt aataatctag cgatagaagc tatgttcttt
     6661 tatattttct atgtctttga tggctattag tgttatttaa cagattgttt atatttatat
     6721 tacgagtatt tcgtatgttt gcgaaaccaa cgtaatgtcc gaatatgctt agaggttggt
     6781 aagcgtgtgt aataacggta taaataactt taaaacggat tgaaaatgaa aaaggcaatt
     6841 atgaacacaa tgatcatcct gtttgctttg gcgatgtgcg taggatgcgg acagtcttcg
     6901 gaacaaaaag aagaaagtgt tccgacagat gtaacaaagg cagaaaaaca agagcaagtg
     6961 caggtggtag cggaggacga agatacgctg gaaaatggag agcaggtatt tagggtggta
     7021 gaggtgatgc cgaagtttcc cggcggtgat gcggagcttt tgaaatttat agccaagaat
     7081 gtaaagtatc cacaagagag ccaagagaaa ggagagcaag gccgtgtgat ttgttcgttt
     7141 gtggtaacga aggatggaac gcttacgaat tacaaggtcc ttagaggaat ctccccggca
     7201 ttagaccaag aggcggttcg ggtcttgcga atgatgcctc gttggacacc gggcacgcaa
     7261 agaggcgagc cggtagccgt gaaatttacg gtgccgatca cgtttaagtt gcaataattc
     7321 acgattgtag gtcttgtgat tcttatttaa tgttaattaa cgtgccttcc gcatgccgtt
     7381 tacgactatt tcgtagcttt gtggatatgc attaataaaa ggataagatt tatggagaag
     7441 ctaacgatgc aggaagaaga ggcgatgcgc tggatttggc ggatcggtcc ttgttttgtg
     7501 aaagatgtgc tggccaaata cgaggacccg aaacctcctt atacgacgct cgcttccgtg
     7561 atcaagaatc tggagcgaaa gaagtacgtg aaggcgaaac gttatggaaa tacgtatgaa
     7621 taccgtcctt tgatagagga aacggaatat aaacgtacgt tccttggcgg cgtggtaacg
     7681 aattatttcg ctaactcgta taaagaaatg gtttctttct ttgcgaaaga tcagaaaatc
     7741 tctacggatg atctaaagga tatcatcgat ttgattgaga aaggaaaaga ataacctaaa
     7801 tcccacatac catgacaccg gaatttgcct acttattgaa ggtaaatgta gcctttgtac
     7861 tcttttacgc cttctaccgg ttgttcttct ataaggacac gttcttcaag ctacgtcgtg
     7921 cgatcttgct ggcgttcttt ggcttggctc tgttttatcc tttgctgaac atccaagatt
     7981 gggtaaggca acaagagcct atagcggacg tgatttatat gtattccgct atgttgcctg
     8041 aggcgacggc gaaagcggat gccgcggcgt ccgtggattg gtatggatgg ttgctgggat
     8101 ctttggggtt tatttattgg gggatcgtag cgttcttatg cggacgtttt ctcgtgcaat
     8161 taagcagtat cttatggttg gctcatacca gtgagcgtgt tgttattcat aaaactccgg
     8221 tttatgcgtt gcggaaggcc gccgggccat tctccttttt ccgtatggtc ttcttgcatc
     8281 cggagagtca ttcggataag gaaacggatg agatattgac acatgaatgt acgcacgtat
     8341 cccaatggca ctcgattgac gtgatcttga gcgagatgat gtgtatggct tgctggttca
     8401 atccttttgt atggttattg aagcgtgagg ttaggcataa tctggagtat ctggcggata
     8461 acacggtgat ccagtccggt tacgatagta agagctatca ataccattta ttgggattgg
     8521 ctcatcatca gtccgttact actttgtata atagtttcaa tgtgctgcat ctgaagaacc
     8581 ggattatgat gatgaacaag aagcggagcc cgggtatcgt acgtacgaaa tatctgatat
     8641 ttattccatt ggtagggatc ttgatgctgt taagtaatat cgaggcggta gcgcgtttga
     8701 ctgtccgtct ggcgaatgag gctacggtct cgaacgctat ggtgacggct acggacgttt
     8761 cttccaaatc ccgtgagatg aacgagcaag tatttaccgt ggtagagaag atgcctagtt
     8821 tcccgggagg ggatgaggag ttgttgaaat acatagccac gaatataaag tatccgaaag
     8881 agagtcagga taacggggag caaggtcgtg taatctgctc gtttatcgtc gggcgtgatg
     8941 gttccgtcaa taacccggag gtgcttcggg gagtgactcc tttattgaat gaggaggccg
     9001 taagggtaat aaacactatg cctcgctgga atccgggaat gcaacgtgga aaggcggtcg
     9061 ccgtgaaata tacggtcccg attacgttcc gtttgaaaag tccggtagaa gaaacgaagg
     9121 aagagacttt gacggtagtg gacgtgatgc cgcaatatcc cggaggggat cgtgaattat
     9181 taaagtttat cgctcaaagc ataaagtatc cgacggatgc gcaggaagcg ggagtgcaag
     9241 gtcgtgtgat ctgttcgttt gtggtagata agaaaggaaa tatcgtggaa cctaaaatca
     9301 tacgggggat agatccctcc ttggatgcgg aagctttgag agtcatcgga atgatgcctc
     9361 ggtggactcc cggtcgtcag gacggaaagg cggtccgtgt cttatatacg gtgcctatta
     9421 ctttccggtt acagtgaaat aagaatagag gctatgttgg tcgcttaatc agtaatctta
     9481 aaaatataca gatatgaatg cgaaatgtaa tttagttaca gttctgttac tttgttgcct
     9541 tatttttccc gggaatgctc aagagtttaa ttggcaagac ttggtgaacc gtaagcaata
     9601 tgcggctgtg atcgcccgtg ccgatagcct taccccggct gattcttctg attatgaggt
     9661 gatgaacgct atcgggcaag cctacgaggg gatgcttcgt taccggcaag cctacgacta
     9721 ttatcgtctt tgcctctcca tggacacgac taatctggat attttaaata cgttggcccg
     9781 aacggctacg aacttgggca aggcgaaaga cgctgagcgg tatttccaca aggtattagc
     9841 ggccgatagc ctaaacttct atgctaatta tcaattggcc cggttgtatt tccagttggg
     9901 cgaatatgag agggcggttg atacgtatga gaaactacaa gcccggaatg aggacaatac
     9961 ggccttatac cgtgcgatcg gcgattgtta ttcccggctg gagcaatacc cgtccgcgac
    10021 gatcgcctat tttcaagcgt ataacttgaa ccgggagaat gcgggactgg cgggtgcttt
    10081 ggtaaataca ttatatcgta tgggtgtcgg tagtccggac tatatattag aaggggtagc
    10141 gatttgcgat accgccttga tctacaatcc ggggaatcgc cagttattac gcagtaaagc
    10201 tttgggcttg tatatggcga aacaattcgc tcaggctgat tccatttact ctggtttgtt
    10261 ggctgatggt gattctactt accttacctt gaaatatggg ggagcctcga agtattacgc
    10321 cggtctgtat atgccctcgg tagatatctt ggatatggct tatgagcagg atacgacctc
    10381 ggtcgaggta tgcctcttat tgggttccgc cttgggtaag acgtatgacc ggaaacgggc
    10441 ttacgattta tttgaccggg cggaaaaggg attggagccc aatcgtttct tggtaaatca
    10501 attattggcc ttccgtgcgg agacttacca aaaggacggg agatataagg aagcgtcccg
    10561 tctctactat gaggcatgga agaagaatcc ggaacgactg gatttccttg cggcaatctc
    10621 gcatatgtat agtgagattg acgtgtctaa attccagagc gaggaggatc gccagcgagg
    10681 gctttttatc ttggtacttt atatgaatga gagcttaaag aaaaaagcgg acgagaggac
    10741 gatggtgttt agccgggcgc ttctgcaatc cttctatgag gatatgtttt tccgtaatgt
    10801 agtggaggag actatgatag acccggatgg gaaaaagagc aagatctcta tcgtggattt
    10861 gcgtaacctg atcaatcaat tgccggagga atcggagatg gtcatggaga ttcgtgccat
    10921 gagcgccaga agctcgggta agatagagga ggcggcccgt ctgctttatc gggcgtggaa
    10981 ggtgaagggt actcgtgtag aattgcttcg tgagatcgcg aacctatata gccatccgga
    11041 tatctccgga ttcaagaatg cggaggagct acagagaggt gtattcgctc aagtgactta
    11101 cgcgaaggaa ctgttgaaaa acgagttgga tctgagtaac ctgactttta cccggccttt
    11161 cttggagtca ttaaattcgg atatgtccaa acggggtatc acggagcaaa ccatgctggc
    11221 tccagataac cggaaaagcc agctttctat agatgaactc caatctctga tccaacaact
    11281 gccggagaca tctgatgagg taaaagagat gatacggatg atgaacaaag agaaagcgct
    11341 aaagagcaag aaatgacatc gaacgaaaga cttttaacat catgaaaatg agaaaatcaa
    11401 tttgacttat taggaaacta taaaaggagt tttaagttca cggataccag ttattataat
    11461 tatatattta attatgatcg tgatcatttg atttgctata agagttatcc atcggaaaaa
    11521 ggcaagcggg agtgtcattt gattatttcc aaacaagatg gccgtatcac tcatgagatc
    11581 caaattccct ctaaggggac tgagactccg gttgtaacag aaggggagtt tatcattacg
    11641 ccggaatttt atcttacgtt tccggatggg gataaatgga tacttgtcaa tacatcgtct
    11701 gataccatat tccattactt gccggataga aatctgagtc cttttatcgt aagaagccct
    11761 tccatatcct ccatggatac taaagtattt ctttttccaa ccgtcatcac cgatcgctac
    11821 tgtttcatga gaaccatgag aaaagagatt gactttacga cgtttaaagg tttccttggt
    11881 gaagatctgg tgtatgataa acaagaaaat gccttattca gctatattct atacaatgat
    11941 gatttcatca ataaggaaga agtctctcta acatcagagc caagaaaccc cgaaatagct
    12001 atctgccaaa ctctagatac cccggactta gttgaggctt acgagaaagg ccagctaaaa
    12061 ggaaagttga aggagatcgc cgcaaacttg agtgaggagt cgaatcctgt ggtcatgctg
    12121 ctgaaaaaga aaaagtaata tattgctccg gctgctacct tgctggaaaa aagtaagttg
    12181 atggctatat tattttttga taaacacgta catacttgat ttataatacg taaatcgatt
    12241 ttagcgagaa atgcctatta attctaagga gattgtatca aatactatcg attgcccact
    12301 tatgttccgg aaataaaatg ttcctctcct gttgaaatag ttctccgata acctatacat
    12361 tccatagcga ataagtattt attcttaaat cagcgccgtg aactgtataa accacgccgt
    12421 ggaatgtgca gaccacgcct tggtttatac agttcacggc atggtttata gaatagatga
    12481 gatagcgata aactttatat ataggtaaac atacgtttta ttctagatga atccgtttgc
    12541 gttttcgagt aaaccagcta catttgccgg aaagaatatc tagatgagga agttcctttt
    12601 attgtggttg gttgggttga tgttggtgcc ttctgtgatg gctgagcgga aaaaggttgg
    12661 cttggtgctg ggaggtggtg gggcgaaagg tgtcgctcat atcggggtgt tgaaggtatt
    12721 ggaggaggcc ggcatcccga ttgattatat tgccggaacc agtatgggag ctatcgttgg
    12781 tggcttgtat tccgttggct atactgccgc tgagatcgat agcatggtac gttggcagga
    12841 ttggagcatg ttgctaagtg accgtgtgaa acgtagtaac cttacttttc cggagaaaga
    12901 gaattccgag cgatatgtct tttcccttcc ttttggccgg agtaaaaagg agataacgat
    12961 ccaagggatg ataaaaggtc aaaatctcca gaaccttttc tctgatttaa cgatcggtta
    13021 tcatgattcc gtagatttta atcaattgaa catacctttc gcttgtgtgg cgttgaatgt
    13081 ggtggacggg caagaatatg ttttccatca tggaagtctt ccgttggcta tgcgtgccag
    13141 tatggcgatt cctgccgtgt ttgcgccggt acgtttggat agcatggtgt tggtagatgg
    13201 tgggatcaag aataactatc cggcggatgt cgcacgggat atgggggcgg atatcattat
    13261 tggcgtagat ctgggtacta gcgacttgaa acagttggag cggataaata ccccttggga
    13321 tatcgtaggg cagatcgtcg ccttgcatgg ttatgagaaa tacggaccga ataaggaaca
    13381 aaccgatctg ttgttccgcc cgaatacaga cccttataat tccgctagtt ttggggagac
    13441 ggccctggat accttgattg accggggtga gcaagtcgcc cgcaagcaat gggatgagat
    13501 tcttgcctta aagaagaaga ttggtttatc cgatagttcg gatatgtacc gaaagagatt
    13561 agtacattcc tatccggtag cccctaccga tacgtttcat atccggcgtg tcttgtttga
    13621 aggtatagat cctcgtgatg agaaatggtt gacgcaaatc agc
//
