LOCUS       c00021_gnlPro..        24212 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POHGCOAF_21.
ACCESSION   c00021_gnlPro..
VERSION     c00021_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:29:58
            Original ID  :: gnl|Prokka|POHGCOAF_21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 21988
            Orig. end    :: 46200
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24212
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[31988:36200](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14212
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..24212
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24212
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(579..1307)
                     /locus_tag="ctg21_20"
                     /transl_table=11
                     /translation="MDDGALIQYKNVEIHQQELCVLSDVNLELHKGEFVYLIGKVGSGK
                     TSLLKTLYGELDVIDGEAEVLGYNMRSIKRKHIPQLRRKLGIVFQDFQLLTDRTVYNNL
                     EFVLRATGWKNKQEIQERIEEVLQLVGMSNKGYKLPNELSGGEQQRIVIARAVLNSPAI
                     ILADEPTGNLDVETGKAIVELLHNICESGSSVVMTTHNLQLLKDYPGRVYRCADHQIVD
                     VTDEYMPRQRTIEIDLNIDN"
     CDS             complement(1349..1960)
                     /locus_tag="ctg21_21"
                     /transl_table=11
                     /translation="MELDFDKMNGLVPAIIQDNETRKVLMLGFMNKEAYDKTVETGKVT
                     FFSRTKNRLWTKGEESGNFLHVVSIKADCDNDTLLIQVEPVGPVCHTGTDTCWGEKNEE
                     PVMFLKALQDFIDKRHEEMPEGSYTTSLFESGINKIAQKVGEEAVETVIEATNGTDERL
                     IYEGADLIYHMIVLLASKGYRIEDLARELQERHSSTWKKH"
     CDS             complement(2091..2846)
                     /locus_tag="ctg21_22"
                     /transl_table=11
                     /translation="VLAKRIVPCLDIKDGQTVKGTNFVNLRQAGDPVELGRAYSEQGAD
                     ELVFLDITASHEGRKTFTELVKRIAANINIPFTVGGGINELSDVDRLLNAGADKISINS
                     SAIRNPRLVDEIAKNFGSQVCVLAVDAKQTENGWKCYLNGGRIETDKDLFEWTKEAQER
                     GAGEILFTSMNHDGVKAGYANEALAALADQLSIPIIASGGAGCKEHFRDVFLQGKADAA
                     LAASVFHFGEIKIPELKSYLCGEGITIRG"
     CDS             complement(2950..3669)
                     /locus_tag="ctg21_23"
                     /transl_table=11
                     /translation="MIEIIPAIDIIDGKCVRLSQGDYDSKKVYNENPVEVAKEFEANGV
                     RRLHVVDLDGAASHHVVNYRVLEQIAVRTSLVIDFGGGVKSDEDLKIAFESGAQMVTGG
                     SIAVKDPELFCHWLEIYGSEKIILGADVKEHKIAVNGWKDESACELFPFLENYIDKGIR
                     KVICTDISCDGMLSGPSIDLYKEMLAKFPDLYLMASGGVSKMDDIVALDEAGVPGVIFG
                     KALYEGYITLQDLRIFL"
     CDS             complement(3688..4278)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_24"
                     /sec_met_domain="GATase (E-value: 2.5e-23, bitscore: 75.7,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVAVVKYNAGNIRSVDYALKRLGVEAVITADKEELQSADKVIFP
                     GVGEAETTMNHLKATGLDELIKNLRQPVFGICLGMQLMCRYSEEGEVDCLNIFDVGVKR
                     FVPQKHEDKVPHMGWNTIGKTNSKLFEGFTEEEFVYFVHSFYVPTCDFTAATTDYIHPF
                     SAALHKDNFYATQFHPEKSGKTGEKILTNFLNL"
     CDS             complement(4278..5132)
                     /locus_tag="ctg21_25"
                     /transl_table=11
                     /translation="MTTAKLLLHCPDKPGILAEVTDFITVNKGNIIYLDQYVDHVENIF
                     FMRIEWELKDFLVPQEKIEDYFRTLYGQKYEMDFRLYFSDVKPRMAIFVSKLSHCLFDM
                     LARYTAGEWNVEIPLIISNHPDLQHVAERFGIPFYLFPITKETKEEQERKEMELLAKHK
                     ITFIVLARYMQVISEQMINAYPNKIINIHHSFLPAFVGAKPYHAAFQRGVKIIGATSHY
                     VTTELDAGPIIEQDVVRITHKDAIEDLVNKGKDLEKIVLSRAVQKHIERKVLAYKNKTV
                     IFS"
     CDS             complement(5999..6421)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_26"
                     /sec_met_domain="Acetyltransf_10 (E-value: 4.3e-18,
                     bitscore: 58.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKIKVTDYPRLMEIWESAVLSTHDFLKEEDFLYYKERLPVYFQ
                     YVNLFGFEQEGILIGFMGIAEGNLEMLFIDNKYRGAGIGKKLITYAIDNLQVTKVDVNE
                     QNVQAVGFYEYMGFNIYKRSNLDGEGKEYPILHMQL"
     CDS             complement(6486..7064)
                     /locus_tag="ctg21_27"
                     /transl_table=11
                     /translation="MLLKKLLKEFNFSTNIFNWEEFKLFDQYFERILVSKGTFLIKEGE
                     TERYSYFVFEGILRCWLLNHNGEEQTFWFCKEGTFSMSNISFTLQTRSAFNVQTIVDSV
                     IYRIDKKQVNELYTAIPKVKTVFEDLNAILLNKLLKRNIDLIKYSPEQYYLQMMEEYGI
                     TLNYIPLKDIASYLGITPQALSRIRKRIF"
     CDS             complement(7170..7733)
                     /locus_tag="ctg21_28"
                     /transl_table=11
                     /translation="MKQIIFIFMSLLCFSCSSKAQNQTADTNVQSDKKILVAYFSCTGT
                     TEKAADAIAKTVGGKLYQITPATAYTSADLDWNNKSSRSSIEMTTENSRPELGGEALNL
                     KDYDVIFLGYPIWWNLCPRPVNTFLEKYDFSGKTVIPFATSGGSSITNSVKQLKKLYPK
                     IVWGESRLLNGSVKQAGEWAKGVI"
     CDS             complement(7962..8789)
                     /locus_tag="ctg21_29"
                     /transl_table=11
                     /translation="MNKLLLFSVFSILTLNVMAQEKIVQTAGRDQLGTFAPKFAELNDD
                     VLFGEVWSRTDKLGLRDRSLVTITSLISMGITDNSLVYHLQSAKKNGITRTEIAEIITH
                     IGFYAGWPKAWAAFNLAKGVWSEDIVGEDAKTAFQREMIFPIGEPNTAYAQYFIGNSYL
                     APVSREQVNISNVTFEPRCRNNWHIHRATKGGGQMLIGVAGRGWYQEEGKPAVEILPGT
                     VIHIPANVKHWHGAAADSWFAHLAFEVSGENTSNEWLEPVTDDEYNKLEQTKR"
     CDS             complement(8801..9238)
                     /locus_tag="ctg21_30"
                     /transl_table=11
                     /translation="MIKTILSVLSLFVMLSCSMTGKKDIKQQPGMCAKLPMAADGIVRL
                     SKIEVYPEYLEEYMKYATEVGEVSLRTEPGVLTMYAVSEKENPGRITILETYASQEAYK
                     FHIASEHFQKYKQGTLHMVKTLVLSDQMPLNPANCINNFIQ"
     CDS             10001..14212
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_31"
                     /sec_met_domain="HGD-D (E-value: 4.6e-22, bitscore: 72.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 3.5e-33, bitscore:
                     108.0, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAYKVGLDIGSTTAKMVVLDKDGTTVLFSGYKRHQAKIQECLLG
                     FLYQIKEQLGDIPLSFHITGSVGMGISEKCSLPFVQEVVAATNYVRREHPHTATMIDIG
                     GEDAKVVFFQDGQATDLRMNGNCAGGTGAFIDQMAILLGVSIDELNELALRSNQVYSIA
                     SRCGVFCKTDIQNLIAKNISKENIAASIFHAVAVQTTVTLARGCNIVAPVLLCGGPLTF
                     IPALRKAFANYLNLSQDTDFILPEKGNLIPAWGAALAENNEESIHLSNLIQVIENKLSV
                     TSPFQSDLSPIFDSEEEYRSWKKEKDQYKIQYASLRPGLQEATIGIDSGSTTTKIVVLD
                     NNHRILYSYYHDNNGNPIKTVENGLQKLYEECRRRGTTLRIKGGCSTGYGEDLIKAAFH
                     MDAGIIETIAHYAAAKHISKEVSFILDIGGQDMKAIFVNDGVINRIEINEACSSGCGSF
                     ISTFAQSLDYSVEDFAKAACFSQAPCDLGTRCTVFMNSKVKQVLREGASVADIAAGLSY
                     SVVKNCLYKVLQLKDTEILGDHIVVQGGTMRNDSIVRSLEKLTGKQTFRSNCPELMGAL
                     GCALYAKQIENARVTELNEMLQWAQYTSKQLQCRGCENQCAIMRYTFNSENHYFSGNRC
                     EKVFSNKGSHADKGINTYDKKLELLFDRSADIPQPLFTIGIPRILNMYEEYPFWHTLFT
                     ACGIQVQLSDPSTFSKYETAAGMVMSDNICFPAKLVHSHIRNLTLQNVNRIFMPFVVFE
                     KKDKQQQNSYNCPIVSGYSEVIKSVQEENIPIDAPTITFKDEALLYKQCYEYLKSLGIR
                     DEVCKNAFSRALQEQYAFEEKIAAYNQEVLNEGREKHKLIILLAGRPYHSDPLIQHKVS
                     DMIAAMGVYVITDDIVRQQEISLEKTHYLSQWAFTNRILKATKWAAMQEGDIQYMQMTS
                     FGCGPDAFLIDEVRNLLKRYGKNLTLLKIDDVNNIGSIKLRVRSLVESLNFSLKHSQAK
                     DPEPFVSTAPFTKKDKKKKILAPFFTPFISPLIPSIMKVAGYEMETLPLSDTASCDWGL
                     KYSNNEVCYPATLIVGDIVKAFKSGRYDPANTCVAITQTGGQCRASNYISLIKKALIEN
                     GYTNTPVVSLAFGSGIENEQSGFKVNWLKVLPIILASVLYSDCIAKFYYAAVVREKERG
                     QAARLRDLYLDTAQPIIQKNKPEDLLSYLYLAARDFNKICEQRSCHKVGIVGEIFLKFN
                     PFAQKDVTSWLINQKIEVIPPLISDFFMQGFVNLKVRQNQHLQRKLTPDFVIDWLYKKV
                     QKQINKVNEIGKSFNYFIPFESIFEKAEKAKQVISLGTQFGEGWLISGEILSFASQGVN
                     HVISLQPFGCIANHIVEKGIEKRIKSLCPQMNILSLDFDSSVSDVNITNRLLLFIDNIN
                     N"
     CDS             14217..14837
                     /locus_tag="ctg21_32"
                     /transl_table=11
                     /translation="MATTEHSDLEQQIIKTAQQLFIEKGFVETSMSDIAATVGINRPTL
                     HYYFRTKDKMFKAVFGSIVMSLMPKIQDIVKQDIPFMERLSMILDEYIELFTSNPCLPR
                     FICGEIQRDVNHLLATAKELQFGDALSQVKDSILTAMEDGKLKKVPIHIVFLTVYSLLS
                     YPFLAKNLIVSLFLEDEAAFADFLQEWKQNIINQLQNLLCYEE"
     CDS             complement(15027..15449)
                     /locus_tag="ctg21_33"
                     /transl_table=11
                     /translation="MMRDAEKTVGNMIDKLKTAFIGSIDGEGFPTIKAMLQPRKRKGIK
                     TIYLTTNTSSMRVAQYRENNHACIYFCDTRFFRGVMLRGTMDVLTDSASKEMIWQEGDT
                     MYYPEGMADPDYCVLKFTAISGRFYSNFKSEDFVVE"
     CDS             complement(15542..16420)
                     /locus_tag="ctg21_34"
                     /transl_table=11
                     /translation="MKNSIPRYTFYKHKYGSELLVDVVELKYVKKFLAKSAVHTLNYYD
                     ITFITEGKGAFSVDNQTYEAIPRDVLFSKPGEIRNWDTHHITNGYALIFEEEFLSFLFK
                     DSLFVQHLSFFQIESSSSLLHLSDELYTRILETLHDIKMEIDSYQQGDVHVLRALLYEV
                     LMLLDRAYLKMTSIEEGRSREVSNNHVSKFMNLVATHAKEQHSVQYYADKLCITPNYLN
                     EMITSTMGISAKQYIQSKVMEEAKRLLVYTDFPIADIAFELCFSTVSYFIRSFRQHTGE
                     TPLLYRKAHKP"
     CDS             complement(16544..17092)
                     /locus_tag="ctg21_35"
                     /transl_table=11
                     /translation="MEAYLKKLCFEYQVDEREVKELLARMEMVYLDKGETIASATLPEQ
                     SLYIIVSGILHTYTTHEGEERTNRFFSAGDAVLCYNSSQYSIKTLTKCAAYYISEEEIE
                     ELCASSISFANLVRQLMEYQFYFKEEEDMNARKLTVRERYLSLLAEIPDILYRVPLKHI
                     NHYLGADVTSLGYLAGSSK"
     CDS             complement(17133..18497)
                     /locus_tag="ctg21_36"
                     /transl_table=11
                     /translation="MKELDLTQGSVPKVLLQFAVPFLIANVLQALYGGADLFVVGQYDD
                     SASVAAVAIGSQVMQTITGIILGITTGTTVLIAIATGAKDNRKVAFTIGSSVWLFSITG
                     VVLTLVMVLFHSRIAELMHTPVEAMVDTKNYILVCSLGILFIVGYNVVCGILRGLGDSK
                     TPLYFVGLACVINIVLDFILVGYFHWGATGAAIATVTAQGVSFGIALWFLYRHGFHFDF
                     SRKDIRLNRNLSKKILVLGAPIALQDALINVSFLIITVIVNQMGVIASASLGVVEKIIV
                     FAMLPPMAISSAVATMTAQNYGAGLIKRMNKCLASGIGIALVFGVSVCVYSQFLPETLT
                     AFFTKDAAVVAMAADYLRGYSIDCIVVSFVFCINSYFSGQGNSLFPMIHSLIATFLFRI
                     PLSYWFSQIDSSSLFIMGFAPPISTVVSLLICIWYLRYTQRKLYLRGTMMPAMSN"
     CDS             complement(18734..20299)
                     /locus_tag="ctg21_37"
                     /transl_table=11
                     /translation="MKNEGSLLSFRRIYYRGKLNSCNYTCSYCPFGKKSHLADTTQDEQ
                     AWNRFIAAIEQWKGEPLQLFIIPYGEALIHRYYRKGMMHLAALPQVSGISCQTNLSFPA
                     KHWLDEIRVAPTVISKIRLWASFHPEMTSVEKFAHQIHILHHAGIQVCAGAVGNPSAKA
                     VLNDLRNALLPDIYLFINAMQGLRAPLSQEDIQFFSQLDNLFEYDLKNAPAQWEVCAGG
                     RDNCFIDWKGDMYACPRSRVKIGNFYQGDGAVVPLSCKRKVCDCYIAFSNLNNHPLHRI
                     MGEGAFWRIPDKPLITTVFFDVDGTLTDSQGKVPESYANALRYMAQSVSLYLATSLSME
                     QAKKKLGKALFDLFRGGVFADGGLLSYSRQIKCLPVKVYPEVYGESSKVTIHSYEGVVY
                     KYSILVRDKEQRESILTRLKENPCQVFHKAPLITIIHPEASKKEGVLQLCKALGLASEY
                     TLVVGNSLKDWPMMSVVSHSCAVMNAEPLLKERARYTLNPDRLAAFFRFSNGDPIDQTS
                     SDNS"
     CDS             complement(20311..21588)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_38"
                     /sec_met_domain="Radical_SAM (E-value: 8.2e-16, bitscore:
                     51.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPLPRYVDYMYSYPHKTAYRSFPSPVSLVPYLKQVEGQKASLY
                     FHIPFCSHKCGYCNLFSLQTNRADYIATYLETLHKQAQQLSPLTTGLAFDSFAIGGGTP
                     LLLTVPQLEYLLDTAALFGVHPSHTFTSVETSPEYADPARLDLLKQAGVARVSIGVQSF
                     LDEELTALKRRPRRDMINQALEAIRKRQFPFFNIDLIYGIKGQTVASFLYSLEQALLFQ
                     PNELFIYPLYVRPGTAITERESDDVCFQMYCAACDLLKDRGFLQTSMRRFIHHPSTDAE
                     ISCGDEVMLSCGSGGRSYLGNLHYATRYTVCQRCIAGEIDDYMGTTDFTVARNGFILSQ
                     EEQRQRFIIKNLMYYMGLDKAEYERRFGESPDNVPLFRQLAERQWIENTDSGRVCLTSD
                     GMAYSDYIGQLFITPEIRELMETYSY"
     CDS             complement(21585..22439)
                     /locus_tag="ctg21_39"
                     /transl_table=11
                     /translation="MQIDELPAGEQTQNPDLDMNQVVGTHDILMLCFDTLRYDVSKEEE
                     EAGRTPVLNSHGGEWEKRHAPGNFTYPSHFAIFAGFLPSPAEPHSLRSRKWLFFPVQAG
                     TGRIPPAGSYPFTEATFVQSLANVGYETICIGGVNFFSKRNELGRVFPGYFTKSYWLPT
                     FGCTAPDSTEKQIDFALKKLENYPEDKRIFMYINFSAIHYPNCHYVEGKMKDDKESHAA
                     ALQYVDSQLPRLFQAFQKRGNTLVIALSDHGTCYGEDGYEYHCISHETVYTVPYKHFIL
                     TKK"
     CDS             complement(22426..23436)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_40"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.8e-07, bitscore:
                     23.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIIVVSNSLSKRIEYFIEAGKHLQVEVRFMTYGELFNCLPQLRQ
                     AVIKLEPCVSDETNFLKYALLNQAYKETLQRLGEMRLSDDVCFLNTPHALLRALDKKET
                     KQVLMDRGLKVTPMLPSPRSFDELRELLTGCGRGCFLKPRYGSGAGGVMAIRYQPNRNK
                     WVVYTTLQQVDGVIHNTKRINRLSTEKEMIPLAEAVMQTEAILEEWIPKEQLQGENYDL
                     RVVCRESEIDYIVVRCSKGSITNLHLNNKAHWWNELSLPEVVRQQIYFQCQEAVQSLDL
                     QYAGVDVLIERGTDIPYIIEVNGQGDHVYQDMFAHNSIYIQQIKNIKKRYNHANR"
ORIGIN
        1 caccgtaagc attgcggcag atgaaacctt gcgtaatgta gatttccgta tccggataaa
       61 gatccagttg agcacgcaac ttatccttaa tatatacggg gtccggttct gcgttcttat
      121 cagtacgcat gaattccaaa gccggaagca acacggactt cacaccacat tcctgcaggt
      181 agaagtttac catcgccgta gagataagct ctccctgtgc caaaaccact ttctcttcga
      241 acaaagtgaa aaggtcttta gtataggagc ggatgtagtc gaagtgggat ttgacaactt
      301 caagaccttt ctgtttatat tcctgggttg caaaaagctc atcaatatgc tgtttatatt
      361 ttgcttccag cttattaata atctcgttgg caccctccgg attcttctta tacagatagt
      421 ccgaaatttc caccaatgtg tttgttgttc ctgacatagc agaaagaaca acaatcttct
      481 gttcaccatc ggtaatcaat ttggctactt ccttcatgcg ctgagcagaa cctacggaag
      541 ttcctccaaa ctttaaaact ttcattttcg ttactgtttt agttatctat atttaaatct
      601 atttctattg ttctctgtct gggcatatat tcatcagtca catctacaat ctgatggtcg
      661 gcacaacgat ataccctgcc cggataatct ttcaacagtt gcaaattgtg cgtcgtcatc
      721 actaccgatg agccggattc gcagatattg tgcaacaatt caacgatggc tttacctgtt
      781 tccacatcca gatttccggt tggttcatcc gccaggatga tagccggaga attgagtacg
      841 gcacgtgcaa tcacaatgcg ctgctgttcg ccaccggaaa gttcgttcgg aagtttataa
      901 cctttgttgg acattcccac cagttgaagc acttcttcaa tacgctcctg tatctcctgt
      961 ttgtttttcc agcctgtggc acgaagcaca aattccaggt tattatatac agtacggtct
     1021 gtgagcagct gaaaatcctg gaatacaatg cctaacttgc ggcgcaattg cgggatatgc
     1081 ttacgtttga tagatcgcat attatagccc agcacttccg cttcaccgtc aattacatcc
     1141 agttcgccat aaagagtctt gagcagactc gttttccccg agcctacttt tccgatcaaa
     1201 tagacaaact ctcctttgtg caattccaga tttacatcac ttagcacaca gagttcctgt
     1261 tgatggattt ctacgttctt atattgtatc aacgccccgt catccatgcc gactcccgtt
     1321 ttaattttta atttctaatc tttacttatt aatgcttctt ccaggtactg ctatgtcttt
     1381 cctgcagttc acgtgcaaga tcttcgatgc gatagccttt tgaagcaagc aatacaatca
     1441 tgtgataaat gaggtcggct ccttcgtaga tcaaacgttc gtcagtaccg ttcgttgctt
     1501 cgatcactgt ttccacagct tcctcaccta ctttttgagc tatcttattg attcccgact
     1561 caaacaggct ggttgtataa gaaccttcgg gcatttcttc gtgacgtttg tctataaagt
     1621 cctgcaatgc tttcaggaac atgaccggtt cttcgttttt ctccccccaa caagtatctg
     1681 tgcctgtatg acacacagga cctaccggtt ctacttgaat caataatgta tcattgtcgc
     1741 aatcagcctt tatagataca acatgaagga agttaccgct ttcttcgcct tttgtccata
     1801 aacgattctt cgtacggcta aagaatgtaa cttttccggt ttctaccgtt ttatcataag
     1861 cttctttatt catgaaaccc agcatcaaga ccttacgtgt ctcgttgtcc tgtatgatag
     1921 ccggaacgag tccgttcatt ttatcgaaat ccaattccat ttttatataa gttctaatta
     1981 ctatttcaat ttacaattac tacctattcg cctacggaat tcttttgcag acagttccta
     2041 tatttatctg actatataat ccatccgcag gaaaacccgg ccggggtgcc tcaccccctg
     2101 atggtaattc cttcgccgca aagatacgat tttaattcgg gaattttaat ttctccgaag
     2161 tgaaaaacac tggcagccaa tgcagcatct gcctttccct gtaaaaagac atcacggaag
     2221 tgctccttac agcccgcacc tcctgaagct atgatgggaa tggagagttg atccgctaaa
     2281 gcggcaagtg cttcatttgc ataaccggct tttacaccat cgtgattcat gcttgtgaag
     2341 agtatttctc ctgctccgcg ttcctgtgcc tctttagtcc actcgaacag atctttatcc
     2401 gtttcgatgc gtcctccgtt caggtaacat ttccaaccgt tttcggtctg tttggcatct
     2461 acagccaaca cacaaacttg tgagccgaaa ttctttgcta tctcgtcaac caaccgggga
     2521 ttgcggatag cggaagaatt gatagaaatc ttatctgccc ctgcattcag cagacggtct
     2581 acatcactta attcattgat tccaccacct acggtaaatg ggatattgat attagcagca
     2641 atccgtttta ccaattccgt aaaagtctta cgtccttcat ggcttgcagt aatgtccagg
     2701 aaaacaagtt catccgcccc ctgttcactg taagcacgac ctagctccac cggatcaccg
     2761 gcttgacgca agttgacaaa attcgttcct ttcacggttt gtccgtcttt tatatccaga
     2821 caaggtacta ttctttttgc taacacaatc ctattttatt tattgttcaa caatttataa
     2881 tctatattcc tgaagctcga ttcttatctt ccttataata aaggtatctt atttattccg
     2941 atacgctcat tacagaaaga ttctcaaatc ttgtaaggtg atatatcctt cgtataatgc
     3001 cttaccgaaa ataactccgg gaacaccggc ctcatccaag gcaacaatat catccatctt
     3061 gctcaccccg ccactagcca tcagataaag gtcagggaat tttgccagca tctctttata
     3121 caaatcgata gaagggccac tcaacattcc gtcacagcta atatccgtac agattacttt
     3181 tcgtatacct ttatctatat aattttcgag aaatggaaaa agttcacagg cactttcatc
     3241 tttccaacca ttgacggcta tcttatgttc ttttacatct gcccccaaaa taatcttctc
     3301 actgccgtat atttccagcc aatgacagaa taattccgga tctttcactg caatgcttcc
     3361 tccggttacc atctgcgcac cgctctcaaa agcaattttc aaatcttcat cactctttac
     3421 tcctccacca aaatctatga caagagaagt gcgtacagca atctgttcca acacccgata
     3481 gttaacgaca tgatgagaag cagcaccgtc caagtctacc acatggagcc tgcgaacacc
     3541 gttcgcttca aactcctttg caacttccac cgggttctca ttatacacct ttttactatc
     3601 gtaatctccc tgggaaaggc gtacgcactt tccatcaata atatcaatgg ctggaataat
     3661 ttctatcatc tatttactat ttgtatctta gaggtttaaa aagtttgtca gaatcttctc
     3721 tcctgtctta ccactttttt ccggatggaa ctgggtagca taaaagttat ctttatggag
     3781 cgcagcactg aacgggtgaa tatagtcagt tgtagcagca gtaaagtcgc aggtcggcac
     3841 atagaagcta tgcacaaaat agacaaactc ttcttcggtg aacccttcaa acaatttgct
     3901 attcgttttt ccaatggtgt tccatcccat gtgcggcact ttatcctcat gtttctgtgg
     3961 gacaaaacgt ttcacgccca catcaaagat attcaaacaa tcgacttctc cttcttcgga
     4021 ataccggcac atcagctgca tgccgagaca aattccaaat acaggctgac ggagattctt
     4081 aatcagttcg tccagtcccg ttgccttcaa gtggttcatg gtagtttccg cctctcccac
     4141 tccgggaaaa ataactttat cggccgattg gagttcttct ttatcagcag taatcaccgc
     4201 ttctaccccc aaccgcttta aagcataatc cacagaacga atattgccgg cattgtattt
     4261 tacaactgct actttcatca gctaaatatt actgttttat ttttataagc caaaactttg
     4321 cgctcgatgt gcttctgcac tgcacgcgaa agaacgattt tttccaaatc ctttccttta
     4381 tttacgaggt cttcaatagc atctttatga gtaatgcgca ctacatcctg ttcaataatc
     4441 ggtccggcat ccagctctgt cgttacataa tgactagttg caccaataat tttcacccct
     4501 ctctggaaag ctgcgtgata aggcttcgcc cctacaaacg caggaaggaa agaatgatga
     4561 atattgataa tcttattcgg ataagcatta atcatctgtt cggagatcac ctgcatatag
     4621 cgtgccaata caataaatgt aatcttatgt ttggcaagca attccatctc tttgcgctcc
     4681 tgttcttctt tcgtctcctt ggtgataggg aacagataga aaggaattcc gaaacgttct
     4741 gccacgtgct gcaaatccgg atgattactt ataataagag gtatctctac attccactct
     4801 cctgccgtat accgggctaa catatcgaaa agacagtgtg acagcttgga tacgaaaata
     4861 gccatacgtg gttttacatc agagaaataa agacgaaaat ccatttcata tttttgcccg
     4921 tagagtgttc tgaaataatc ttcaattttt tcctgtggaa ccaaaaaatc tttcagttcc
     4981 cattcaatac gcatgaagaa gatgttctct acatgatcta catactgatc caaatagata
     5041 atatttcctt tgtttaccgt aataaagtct gtcacttccg ctaggattcc cggtttgtcg
     5101 ggacagtgca ataacagttt ggctgttgtc atcattcttt ctactaatta acgattctag
     5161 gcagattatt ttctaccttt ctaattttag tccgcaaaaa taacgattta ttgcaaaatt
     5221 acgaattatt caagcagaaa gttgatataa aaacggtgat ttcttacaga tagaaagata
     5281 tcgagagtta ttttcaatga aaagaatgac aaactttagg atagtgatgc cattgccttc
     5341 ggatagtgac ggtattccat cgtgatagcg tcactataac gatcagatac cgtcgctatc
     5401 cgaagagaag aaaaacgaat attttttttc attacaaaag tactcaaaat gagacactaa
     5461 gcatttttct tgttttttct tgaaaaaaac ttttctcaaa acgcttgcag gtttacaaaa
     5521 aacaactacc tttgcacccg caatcgagag agatgcagat taataaattg aaattctggt
     5581 gcgttagttc agttggttag aatacatgcc tgtcacgcat ggggtcacgg gttcgagtcc
     5641 cgtacgcacc gcttctttca ctaagaagca gaaagaaata gaaatgagtt aatccgatta
     5701 aaatttggtg cgttagttca gttggttaga atacatgcct gtcacgcatg gggtcacggg
     5761 ttcgagtccc gtacgcaccg cgaaagcaaa tagtaaatta aagcaaagct ctgaaattca
     5821 agaaattcag agcttttttc tttttcttca cttcatttaa aacagagttt aagtaggcga
     5881 tagatgtgcc cattcaaact ctacaatgat tttttaacca atcattttat tcaaatgtaa
     5941 cattacatct tcaattaaag gtacctatac taagcatctg tttataattg aacagagact
     6001 acaactgcat gtgtaaaata ggatattcct taccttctcc gtccaaattc gaccttttat
     6061 atatgttaaa acccatatat tcataaaaac cgacagcttg aacattttgc tcattcacat
     6121 caactttagt tacttgcaaa ttatctatgg cataagttat taattttttt ccgattcctg
     6181 cgcctcgata cttattgtca ataaataaca tttcaagatt tccttctgca attcccataa
     6241 atccgattaa gattccctct tgttcaaatc cgaatagatt aacatactga aaatataccg
     6301 gaagtcgttc cttataatat agaaaatctt cctctttaag aaaatcatgt gtactcaata
     6361 ctgcactttc ccaaatttcc atcaaacgtg gataatccgt aactttaatt tttctaatca
     6421 tacttgtaat tgcaatttaa agccgcaaag ttcgttactt atacattcaa aacactgaac
     6481 ccaagttaaa aaatacgttt acggattctg cttagtgctt gcggtgtgat acccaaataa
     6541 gaagctatat cttttaatgg tatatagttt aatgtaatac catattcttc catcatctgt
     6601 agataatact gttcaggaga atatttaatc aagtcgatat ttcttttcaa aagtttattc
     6661 aacaatatag catttaaatc ttcaaataca gtttttactt tagggatagc ggtatatagt
     6721 tcatttactt gcttcttgtc tattcggtaa ataacactat ctacaattgt ttgcacatta
     6781 aatgcagacc tagtttgtaa tgtaaaagat atgtttgaca ttgaaaacgt accctcttta
     6841 caaaaccaga aagtttgttc ttccccgtta tgatttaaaa gccaacaacg taatattcct
     6901 tcaaaaacga aataactata cctctctgtt tctccttcct taatcaaaaa tgtaccttta
     6961 ctaactaata ttcgttcaaa atattggtcg aataacttaa actcctccca attaaaaata
     7021 ttagtactaa aattaaattc tttaagtagt ttttttaaaa gcataatcta aatatgattc
     7081 gtaatatact tactcattta atatattcac tattacttcc gccctattta acttctcata
     7141 tttagtgaat atattttcag tagccatttt tatattactc ctttcgccca ctctccggcc
     7201 tgcttgacac ttccgttcaa caatcggctt tctccccata cgatttttgg ataaagtttc
     7261 ttgagttgtt ttacactatt agttatcgag cttcctccgg aagtagcaaa tggaataacg
     7321 gttttaccgg agaaatcata tttctcaagg aatgtattga ccggacgcgg acataaattc
     7381 caccatatcg ggtaaccaag gaatatcacg tcgtaatctt tcagattaag cgcttctccc
     7441 cccaattccg gacgtgaatt ttcagtcgtc atttcaattg aactacggct actcttgttg
     7501 ttccagtcga gatctgccga ggtataggct gtagcgggag ttatctgata aagtttgccg
     7561 ccaaccgttt ttgcaatggc atcggcggct ttttctgtag ttccagtaca agagaaatag
     7621 gcaaccagga ttttcttatc ggactgtaca ttagtatccg ctgtctgatt ctgcgctttt
     7681 gatgagcagc taaagcaaag gagactcata aatatgaata taatctgttt cattttattt
     7741 tgattttaaa tatttcttat cattaattag tttagacatt atcacgatgg agtaacccca
     7801 caggcgtttt cattcttcca ttactttgat aattgcccat atcgtccatc aaacgatgta
     7861 tttcttctgt attaagcgct ttgcgcgtct ttacatattc cttaaaattc ctcggtagtc
     7921 atattatttc ctttcaaaag ataaagcagg attagcaaaa atcatcgttt agtctgttcg
     7981 agtttgttat actcgtcatc tgtgaccggc tcaagccact cattggaagt gttttcgccg
     8041 gaaacttcga aagccagatg agcaaaccaa ctgtcggcag cagctccgtg ccagtgtttc
     8101 acattggcag gaatatggat aaccgtacca ggcagaatct ctaccgccgg tttaccttct
     8161 tcctgatacc agcctcgacc ggctacaccg ataagcatct gtccgccacc tttcgttgca
     8221 cggtgaatat gccagttatt gcggcaacgt ggttcaaaag taacgttaga gatattcacc
     8281 tgctcgcgcg aaaccggagc aagataactg ttaccaataa aatactgtgc ataggctgta
     8341 ttgggttcac caatagggaa aatcatctca cgctggaaag ctgttttggc atcctcacca
     8401 acaatatctt cagaccatac tccttttgcc aaattgaacg ctgcccacgc tttcggccaa
     8461 cctgcataga aacctatatg agtgataatc tctgcgatct ccgtgcgggt gatgccgttc
     8521 ttcttcgccg actgaagatg ataaacgagc gaattgtccg tgattcccat actgataagg
     8581 gaggtaatgg ttactaaact gcggtcacgc agaccgagtt tgtcagtgcg gctccaaact
     8641 tctccaaaga gaacatcgtc attaagttcc gcaaacttgg gggcaaacgt tcctaactgg
     8701 tcgcgtcctg ccgtctgtac tatcttttct tgtgccataa cattgagtgt taaaatacta
     8761 aatactgaaa ataaaaggag tttattcata atcatttcgt ttattgaatg aagttattaa
     8821 tgcaatttgc ggggttaagc ggcatttggt cagagagtac gagagtctta accatgtgca
     8881 gcgttccttg cttgtacttt tgaaaatgct ccgatgcaat atgaaattta taagcctcct
     8941 gactcgcgta agtttcaaga atagttatcc tgccaggatt ctctttttcg ctgacggcat
     9001 acatagtcag cactcccggt tcagtacgca aggagacttc acccacttcg gtcgcatatt
     9061 tcatatattc ttcaagatac tccggataaa cctcgatttt cgatagccgc acaataccgt
     9121 cagccgccat aggtaatttg gcgcacatac caggctgctg ttttatatcc tttttccctg
     9181 tcatactgca tgataacata acgaataaag acaaaacact tagaattgtt tttatcatca
     9241 tcttctatct tttcattgtt aaacttctaa ttgcaaattt actgcgataa aatgaatggg
     9301 cttgtatatc aattacggat ttttgtaccc aaatccccga ttctgtaata aagccgaata
     9361 aaaatcagat attagaagta aagttattca tctgttttaa aaccgataag atacttttct
     9421 catcagactc ttgacaaagg actttttatg ttgtatcttt gagaaaagaa aaagtataaa
     9481 caacatgaaa atagaaagaa ataatcatac ataaatcata aataacctgg tattttacaa
     9541 taccactcct atacgatatg gggcaatagt cgaatgatta ttgccccatt ttgtttataa
     9601 ttcagcttaa aatctctcgt ctgattctaa aactgttcta caatagttta taataaactc
     9661 gaataccgtt ttactaaaac tatcaaaaag tttattataa acagaatccg ggtttattaa
     9721 aagccacgtt tccttttgtc aaaaatagag taaacaagat ttctaggatt caccataaaa
     9781 gatctgctac aaccttacaa gtaatataaa catacaatca ttcatttact tctttattta
     9841 cacaatcatt ttcctctctc acattccatc tttctttttt cccaattcgt taattaaacc
     9901 caaaacttca attacgattt gccgtatcta ccatattttt acatacattt gcgtctgaca
     9961 ctggtgtcag acacgaggtc taatttaaga tgtttggtat atgaatgcat ataaagtggg
    10021 tttagatata ggctctacta ccgccaagat ggtagtattg gacaaagatg gaactacagt
    10081 cttgttttcc ggatacaaaa ggcatcaggc aaaaatacaa gaatgtttac tcggatttct
    10141 ttatcaaata aaggaacagt tgggtgatat tcctttatct ttccatatta cgggctctgt
    10201 tggaatggga atttcagaga aatgctctct gccgtttgtg caagaggttg tagctgcaac
    10261 aaactatgtg cgccgggagc atccgcacac agccactatg atcgatattg gaggagaaga
    10321 tgcgaaagtt gttttctttc aggacggaca ggctacagac ctgcgcatga atggaaattg
    10381 cgccggcgga accggggctt tcattgacca gatggctatt ctgcttggag tctccatcga
    10441 cgaattgaat gaactagcac ttcgttccaa tcaggtatac tctatcgctt cacgctgcgg
    10501 agtattctgc aaaacggaca tacagaatct gatagccaaa aatatatcta aagaaaatat
    10561 agcagcttcc attttccatg cagtagccgt acagaccact gtcacacttg cacgcggttg
    10621 caatatcgta gctccggtat tactctgcgg tggcccattg acttttattc cggcccttcg
    10681 gaaagcattt gccaactatc tgaatctgtc acaagataca gatttcatat taccggaaaa
    10741 aggaaatctg atccctgcct ggggagcagc attggcagag aacaatgaag aaagtattca
    10801 tctctccaac ctgatacagg taatagaaaa caaactaagt gttacctcac ctttccagag
    10861 tgatctttct cctatattcg acagtgagga agaatatcgg tcatggaaaa aagaaaaaga
    10921 ccagtataaa attcaatatg ccagtctgcg tcccggatta caggaagcaa ctatcggcat
    10981 agactccggc tctactacca ccaaaatcgt agtactcgac aacaatcatc gtatccttta
    11041 ctcctattat cacgacaaca acggaaaccc tataaaaaca gtagagaacg gcttgcagaa
    11101 actatatgaa gaatgccgga gacgaggaac taccctgcgc ataaaaggag gatgttctac
    11161 cggttacgga gaagatctga taaaagcggc tttccacatg gatgcgggaa tcattgaaac
    11221 catcgctcat tatgctgctg ccaaacatat cagcaaagaa gtttctttta tcctggatat
    11281 tggagggcag gatatgaaag ccatctttgt gaacgacgga gtaatcaaca gaatcgaaat
    11341 caatgaagcc tgttcctccg gttgcggttc ttttatcagc acatttgcgc aatcgctgga
    11401 ttacagtgtg gaggactttg ccaaagcagc ttgtttttcg caagcaccat gtgatctggg
    11461 tacacgttgc acagtcttca tgaactccaa agtaaaacag gtacttcggg aaggagcgtc
    11521 cgtagcggat atagctgccg gattatctta ttccgttgtt aaaaactgcc tgtataaggt
    11581 tctgcaatta aaagacacgg agatacttgg cgaccatatt gtcgtgcagg gaggaaccat
    11641 gcgtaatgat tccatcgtac gaagtctgga aaagctgacc gggaaacaaa ccttccgcag
    11701 taactgtcct gaattgatgg gtgctcttgg ttgtgcccta tatgccaaac aaatcgaaaa
    11761 tgcccgggtg acggagctga acgagatgct ccaatgggca caatatactt ccaagcaact
    11821 tcaatgccgg gggtgcgaga accagtgcgc catcatgcga tatacgttca acagtgaaaa
    11881 ccattacttc tccggcaacc ggtgtgagaa ggtgttttcc aataaaggaa gccatgcgga
    11941 caaaggcatc aatacgtatg ataaaaagct ggaattatta ttcgaccgga gcgcagacat
    12001 tccacaaccc ctattcacca taggtattcc acgtattctg aacatgtatg aggaataccc
    12061 tttctggcat accttattta ctgcttgcgg cattcaggta cagttgtcgg acccctctac
    12121 attcagcaaa tacgagactg ctgccggcat ggtgatgtct gataacatct gcttccctgc
    12181 caaacttgtg cacagtcata tccgtaacct gacactgcaa aacgtcaacc ggatatttat
    12241 gccgttcgtt gttttcgaga aaaaggataa gcaacagcaa aacagctata attgccccat
    12301 cgtttccggt tattcggaag tcatcaaaag tgtacaggaa gagaatatac cgatagatgc
    12361 tccgactatc accttcaaag atgaagcatt gctgtataaa caatgctatg aatatctgaa
    12421 atctttgggt atcagggatg aggtatgcaa aaatgccttc tcacgcgcat tacaggaaca
    12481 atatgctttc gaagaaaaaa ttgctgccta taatcaggaa gttctgaacg agggacggga
    12541 aaaacacaaa ctgattatct tactcgccgg acgcccttac catagcgatc cactgataca
    12601 gcacaaggtt tcggacatga ttgctgcgat gggagtttat gtgataactg atgatattgt
    12661 ccgccagcag gagatttcat tggaaaagac tcattacctc tctcaatggg catttaccaa
    12721 ccgtattctg aaagcaacca agtgggcggc aatgcaagag ggtgacatac aatatatgca
    12781 gatgacttct tttggctgcg gtccggatgc tttccttata gatgaagtac gtaacttgct
    12841 gaaacgatac ggcaagaatc ttactttgct caagatagac gatgttaata atatcggctc
    12901 catcaaatta cgagtccgct cgttggtgga aagcttgaat ttcagtttga aacattctca
    12961 agcgaaagat cccgagccat ttgtttcaac tgctcctttc accaagaaag acaaaaagaa
    13021 gaaaatcctc gctccattct ttacgccttt catttcacca ctcattccat ccatcatgaa
    13081 agtggccgga tatgaaatgg aaacgttacc gttgagcgac accgcatctt gcgactgggg
    13141 attgaaatac tccaataatg aggtatgtta tccggcaaca ttgattgtcg gcgacatagt
    13201 aaaagccttt aaaagcggac gttatgatcc tgccaatacg tgcgttgcca tcacacaaac
    13261 cggtggacaa tgtcgtgcca gcaactatat ttcactgata aaaaaggcat tgattgagaa
    13321 tggatacacc aatacaccgg tggtatcact tgctttcggc agtggtattg aaaatgagca
    13381 atccggtttt aaagtaaact ggctcaaggt tttgccaatc atacttgcgt ctgtgttata
    13441 cagtgattgc attgccaaat tctattatgc agctgtcgtt cgtgagaaag aacggggaca
    13501 ggccgcccgt ctgcgcgatc tttatctgga tacagcacag cccattatcc agaaaaataa
    13561 accggaggac ttgttgagct acttatatct cgctgccaga gacttcaaca aaatctgtga
    13621 acagagatcc tgtcacaaag taggtattgt tggggaaata ttcctgaagt tcaacccttt
    13681 tgctcaaaag gacgtcacct catggctcat caaccagaag atcgaagtga ttccgccact
    13741 gataagtgat ttcttcatgc agggatttgt caacctgaaa gtgagacaga accaacactt
    13801 gcagcgaaaa ctcactcccg actttgttat agactggtta tacaagaaag tccagaaaca
    13861 aattaataag gtgaatgaaa tcggcaaaag tttcaattac ttcataccgt tcgaatctat
    13921 ctttgaaaag gcagaaaaag ctaaacaagt catctccttg ggcacccagt ttggagaggg
    13981 ttggctgata tccggtgaaa tactatcctt tgcttcccaa ggagtcaatc atgtcattag
    14041 cttgcaacct ttcggatgca ttgccaatca cattgtagaa aaaggaatag aaaaacgtat
    14101 aaaatcgctg tgccctcaaa tgaatatact atctttagac tttgacagta gcgtcagcga
    14161 tgtgaacata acaaacagat tattactttt tattgacaac ataaacaact aaaattatgg
    14221 ctacaacgga acatagcgat ttagagcagc aaataataaa aactgcccaa caacttttta
    14281 tagaaaaagg atttgtggag accagcatga gtgatattgc tgcaacggta ggaatcaacc
    14341 gacccacttt acattattat ttcagaacca aagataagat gttcaaagcc gtattcggct
    14401 cgatagtcat gtctttaatg ccgaaaatac aggatatagt aaaacaggat atcccattta
    14461 tggagcgact gagcatgatt ctggatgagt atattgagct tttcacaagt aatccctgtc
    14521 ttcccagatt catttgcggg gaaatacagc gtgatgtaaa ccacttgctt gccactgcaa
    14581 aagaacttca gttcggagat gctttatccc aagtgaaaga cagtatactg acagcaatgg
    14641 aagacggtaa acttaaaaag gttccgatac atattgtatt tctgactgtc tacagcctat
    14701 tgagctatcc atttcttgcc aagaacctga tagtatcttt attcttggaa gatgaagccg
    14761 cttttgctga cttcctgcaa gaatggaaac aaaacatcat caaccaattg cagaacttat
    14821 tgtgttatga ggaatagtat agatactata taaggaggtg tgtcataatg aataataaaa
    14881 cgcagattaa cgcaaattat cgcagattat tccaattata ttgatatatt aatcaacgat
    14941 ttataaaatt atttctgcga taatttgcat taatctgcgt tttgacacac tccgttatta
    15001 ccattcaaat caccccatct tgcaccttat tcgaccacaa aatcttccga tttaaaatta
    15061 ctatagaaac gtcctgaaat agcagtaaac ttcaatacac agtaatcggg atccgccatt
    15121 ccctccggat aatacatggt atctccctcc tgccagatca tctctttact ggcactatcc
    15181 gtcaagacat ccatcgtacc gcgtagcatg acacctctaa agaatctcgt atcacagaag
    15241 tagatacacg catggttgtt ctcacggtat tgcgccacac gcatggacga cgtatttgtt
    15301 gtcagataaa tcgtttttat cccctttctt tttctgggtt gcaacattgc tttgatggta
    15361 ggaaatcctt caccgtctat cgaaccgata aaagctgttt tcagcttatc aatcatgttg
    15421 cctactgttt tttccgcgtc tctcatcatt ttacttttta ttattggttt attatctgat
    15481 gcgaaagtag agaaatgcca ggaaagcaat gcaataaaaa gaaaggtaga aatagcactt
    15541 tttacggttt gtgtgcttta cgatacaata acggagtttc tcccgtatgc tgccggaagc
    15601 tacggataaa ataagaaacc gttgaaaaac agagttcaaa tgcaatatca gctataggaa
    15661 agtccgtata aacaagcagc ctcttagcct cttccatcac cttgctctga atatattgtt
    15721 ttgcgctgat tcccatggtc gaggttatca tctcattcag ataattagga gtaatgcaga
    15781 gcttatccgc ataatattga accgaatgtt gctcttttgc atgtgtagca accaaattca
    15841 tgaatttact tacatgatta ttggaaactt ccctacttct gccctcctct atcgaagtca
    15901 ttttaaggta agcacggtcc agcaacatca ggacttcata aagcaatgct ctcaaaacgt
    15961 gtacatcgcc ctgttgatac gaatcaatct ccatctttat atcatgcaag gtttcaagta
    16021 tgcgtgtata aagctcatca gacaaatgta gtagcgatga agaactttct atctgaaaaa
    16081 acgaaagatg ctgtacaaac aaagaatctt taaagaggaa agacaaaaat tcttcttcga
    16141 aaatcagagc atacccattg gtaatatgat gagtatccca gttccggatt tcccccggtt
    16201 tagagaaaag aacgtcacga ggaattgctt cataggtttg gttatcgact gaaaaagctc
    16261 ccttaccttc tgttataaaa gtaatatcat aataatttag agtgtggaca gcacttttag
    16321 ccaggaactt cttcacatac ttcagttcta ctacatcgac caaaagttca ctcccatact
    16381 tatgcttata aaaagtatat cgaggtattg agtttttcat tcagaataca aaaatagtat
    16441 tccttaccaa ataatccaaa gacttttcaa attcgattcg attgaataag ccatgaacca
    16501 tctgataagg aatacataga aaaatatgtc taggttatat ttcctattta gaacttccgg
    16561 ccagatatcc caaactggtc acatctgccc ccaagtaatg attaatgtgc ttcaatggca
    16621 ccctgtacag aatatccgga atttccgcca ataaagagag gtacctttcc cttactgtca
    16681 gcttgcgggc attcatatcc tcttcctctt taaagtaaaa ctgatactcc atcagttgac
    16741 ggaccagatt cgcaaatgaa attgaagatg cacacaactc ttcaatctcc tcttcactga
    16801 tgtaataagc agcacatttc gtcagtgtct tgatagaata ctgacttgaa ttatagcata
    16861 acacagcatc acccgcagag aaaaaccgat tggttctctc ttctccttca tgagtggtat
    16921 atgtatgcaa aataccggaa acaataatgt acaagctctg ttctggcaat gtggcagaag
    16981 caatcgtttc tcctttatcc agatacacca tttccattcg agccaacagc tctttcactt
    17041 ctctttcatc cacctgatac tcaaaacaga gtttcttcaa ataagcttcc atacaaaata
    17101 gattttagtt aatatatgtc acttaaaaac acctaattcg acatagcagg catcattgtg
    17161 cctctcaaat ataatttcct ttgggtatat cgtaaatacc agatacagat caataatgaa
    17221 acgaccgttg aaatgggtgg agcaaatccc atgataaaca gcgacgagct atctatctgg
    17281 ctgaaccagt atgacaacgg tatacggaac aggaaagtgg ctatcagact gtgaatcatc
    17341 gggaataacg agtttccttg tccgctgaaa taagaattaa tgcagaacac gaaactaacc
    17401 acgatgcagt cgatgctata ccctcgcaaa taatctgccg ccattgccac cacagcagca
    17461 tctttcgtaa agaaagcagt aagagtctcc ggcaggaatt gcgaatacac gcaaaccgac
    17521 acaccgaaaa caagagcaat cccaatcccc gaagccagac atttattcat tctcttgata
    17581 agtcccgctc catagttctg tgcagtcatg gttgccacag ccgatgatat agccatcgga
    17641 ggcagcatag caaacacgat gattttctca acaacaccca gggaagcaga tgcaatgact
    17701 cccatctgat tgacaatgac agtgataatc agaaaagaaa cattgattaa agcatcctgc
    17761 aaagcaatag gtgctcccaa caccaagatc tttttagaca gattccggtt caatcgaata
    17821 tctttccgtg aaaagtcaaa atggaatccg tgccggtata agaaccagag cgctattcca
    17881 aaactgactc cttgtgcagt tacagtagcg atagccgctc ccgtagcccc ccaatgaaaa
    17941 taaccgacca atataaaatc gagcactata tttatcacac atgccagccc aacaaaataa
    18001 agtggtgttt tagaatcacc caatccacgc aaaataccac atacaacatt atatcctact
    18061 ataaacagaa tacccagaga gcataccaaa atatagtttt tcgtatctac catcgcttcg
    18121 acaggagtat gcatcagttc tgctatccga ctatgaaaaa gcaccatgac caaagttagc
    18181 actacgccgg ttattgaaaa caaccatacg gaagacccga tagtaaaagc tactttccga
    18241 ttgtctttag ctccggtagc aatagcaatc agcactgttg tcccggtagt aatacccaga
    18301 ataatacctg taattgtctg catcacctga ctaccaatag ctacggctgc cacacttgcc
    18361 gaatcatcat attgtccgac aacgaaaagg tcagctccgc cataaagtgc ctggagcaca
    18421 ttggcaatca gaaaaggtac tgcaaactgc aacaatacct tcggtacgct tccttgtgtc
    18481 aaatctaact ctttcatagt ttcttcgata cttttcctct ttatcttatt ttgttacaac
    18541 ataaaaaagt gccggacaag cgaatgattt gcaccattca tcttatccag cactataatt
    18601 attattatag caccctccga tgaggatttt tatgcctgtc cctatttcag ggctgcaaat
    18661 atgggctttg ttttcataat taccaaattt taaccggttt ttattttctt atgaagatgt
    18721 aactagctat atatcaacta ttatcagacg aggtttggtc tataggatct ccgttagaaa
    18781 aacgaaagaa agctgccaac cgatccggat tcagcgtata acgtgcgcgt tcttttaata
    18841 agggttccgc attcattacg gcacaagaat gagaaaccac ggacatcatc ggccagtcct
    18901 ttaacgaatt tcctacaact aaagtgtatt cagaagctaa acccaaagct ttacataact
    18961 gaagcacccc ctctttttta ctcgcttcag gatgaatgat tgttatcagc ggagctttat
    19021 gaaagacctg gcagggattt tctttcaacc gggtaagaat agattctctc tgttctttat
    19081 cacgtaccaa tatactatac ttgtaaacca ctccttcata actatgaata gtaacttttg
    19141 acgattctcc atatacctcc ggatatactt tcaccggcaa acacttaatc tgccgcgaat
    19201 aagataataa acctccatct gcaaacactc ctcccctgaa taaatcaaaa agagcctttc
    19261 ccagcttttt cttcgcctgc tccatcgaca gagaagtggc aagatataag gaaacggact
    19321 gtgccatata tcgcaaagcg ttagcataac tttctggaac ttttccctgt gaatcagtca
    19381 gtgttccatc cacatcgaag aaaacagtcg taataagtgg cttgtccggt attcgccaga
    19441 acgccccttc tcccattatt cgatgtaaag ggtgattgtt caggttacta aatgcaatat
    19501 aacagtcaca aaccttcctc ttgcaagata acggcacaac agctccatca ccttgataaa
    19561 aattacctat cttcacccgg cttcggggac aagcatacat atcccctttc caatcgataa
    19621 aacaattatc ccttcctcct gcgcaaactt cccattgtgc cggagcattc ttcaagtcat
    19681 actcaaaaag attatccagt tgactgaaaa actgaatatc ttcctgactt aatggtgccc
    19741 ttaacccttg catagcatta atgaataaat aaatatccgg taaaagagca ttccgtaaat
    19801 cattaagtac agcctttgca gagggatttc ctaccgctcc ggcacatacc tgtattcccg
    19861 catgatggag tatatgaatc tgatgcgcaa atttctctac cgaagtcatc tcaggatgaa
    19921 aactagccca aagccttatc ttacttatca cagtgggagc cacacgaatc tcatcaagcc
    19981 agtgtttagc cggaaaagaa aggttagtct gacaggaaat tccggacacc tgtggcaatg
    20041 ccgccaaatg catcattcct ttccgataat aacgatggat caacgcttca ccgtaaggaa
    20101 taataaatag ctgcaacggc tcccctttcc attgttcaat agctgctata aaacgattcc
    20161 atgcctgttc atcctgtgtc gtatctgcca gatgcgactt tttgccgaaa ggacaataag
    20221 aacaggtata attgcagcta ttcaatttgc cgcggtaata tatacgcctg aaggaaagta
    20281 aagagccttc gtttttcatt tctatttcgt tcaataagaa taagtttcca tcagttctct
    20341 tatttcagga gtaatgaaca actgaccaat ataatcggag tatgccattc cgtcggaagt
    20401 cagacaaaca cgaccgctat ccgtattttc tatccattgc cgttcagcta actgtcgaaa
    20461 caacggcaca ttatccggtg attctccaaa acgacgctca tattcggcct tatcaagccc
    20521 catataatac atcagatttt taatgataaa acgttgccgc tgttcttcct gcgaaagaat
    20581 aaatccatta cgagccactg taaaatcagt agtgcccata taatcatcta tctctccggc
    20641 aatacaacgc tgacaaacag tatagcgggt ggcataatgc aaattaccca ggtaactgcg
    20701 tccgccggag ccacacgaca acatcacttc atccccacat gagatttccg catcagtaga
    20761 cggatgatga ataaaacgtc gcatcgacgt ttgtagaaaa cctctgtctt tcaacaaatc
    20821 acaagcggca caatacatct gaaaacagac atcgtcggat tcccgctccg tgatagccgt
    20881 tcccggtcgc acatatagcg gatagataaa gagttcgtta ggctgaaaca gaagagcctg
    20941 ttccaatgaa taaagaaagc tggccacagt ttgtcctttg attccgtaaa tcaaatcaat
    21001 attaaaaaac gggaattgtc tcttccgaat agcctccagc gcctgattaa tcatgtctcg
    21061 ccggggacgt cttttcaaag cagttaattc ttcgtcaagg aaactctgta cgccaatact
    21121 cacacgagcc actcctgctt gcttcaataa gtccaaacgg gcaggatcgg catattccgg
    21181 cgatgtttct acggaagtaa aggtatgtga aggatgcact ccgaataagg cagctgtatc
    21241 cagtaagtat tccagttgag gaacagtgag gagcaatggt gtgcctcctc caatggcgaa
    21301 actatcaaat gccagtccgg tagtgagtgg agacaactgt tgcgcctgct tgtgaagagt
    21361 ttccaaataa gttgcgatat aatccgcacg atttgtttgc agagaaaaca ggttgcaata
    21421 tccacattta tgactacaaa aaggaatatg aaaataaagc gatgctttct gtccttccac
    21481 ctgtttcagg taaggaacca gcgaaaccgg ggacggaaaa gaacgataag cagttttatg
    21541 tgggtaacta tacatatagt ctacatatcg tggtagcggt tgattcattt tttcgttaaa
    21601 ataaagtgtt tgtaagggac tgtataaacc gtttcgtgag atatgcaatg atattcatat
    21661 ccatcctctc catagcaagt gccatgatcg gaaagagcaa tcaccagcgt atttccccgt
    21721 ttctgaaagg cctgaaataa gcggggtaac tgactgtcga catattgcag cgcggcagcg
    21781 tgtgattcct tatcatcctt cattttgcct tccacataat gacagttcgg ataatgaata
    21841 gcagaaaaat tgatatacat aaaaatccgc ttgtcctccg gatagttttc gagtttcttc
    21901 aatgcaaaat caatttgttt ttcagtacta tcgggtgccg tgcatccaaa ggtcggcagc
    21961 caataacttt tagtaaagta accgggaaac acacgcccca gttcattacg cttgctgaag
    22021 aagttcaccc ctcctataca aatcgtttca taacctacat tggcaaggct ttgcacaaaa
    22081 gttgcttccg taaacggata acttcccgca ggcggaatac gtcccgtacc agcttgcaca
    22141 gggaaaaaca accacttacg gctgcgtagc gaatgaggtt ccgccggaga aggcagaaat
    22201 cctgcaaaga tggcaaaatg agacgggtaa gtaaaatttc ccggcgcatg tcttttttcc
    22261 cattctcctc cgtgactgtt cagtaccggt gttcttcctg cctcttcttc ctccttgctg
    22321 acatcataac gcaaggtatc aaagcaaagc atcaatatat catgagtacc caccacctga
    22381 ttcatatcca gatccggatt ttgggtctgt tcgccagccg gcagttcatc tatttgcatg
    22441 gttatatctc ttttttatgt tttttatctg ttgaatataa atagaattat gagcaaacat
    22501 atcctgatac acatgatctc cctgtccgtt gacttctatt atataaggaa tatctgttcc
    22561 tctctctatc agtacatcca ctccggcata ttgcaaatcc aaagattgaa ccgcttcctg
    22621 acactgaaaa tagatttgtt gccgcactac ttccggcaaa gacaattcgt tccaccaatg
    22681 tgccttattg ttcagatgca gattggttat gcttccttta ctgcatctca caacgatata
    22741 atcaatttca gattcccggc acactacccg aagatcataa ttctctccct gcaactgctc
    22801 tttaggaatc cattcttcta aaatagcttc tgtttgcatc acagcttccg ccaacgggat
    22861 catctctttt tccgtactca aacggttgat acgtttagtg ttatgaatga ctccatccac
    22921 ttgttgcaag gtagtataga ctacccattt attccggttg ggttgatagc gaatagccat
    22981 aacgcccccc gcccccgaac cgtaacgggg ttttaaaaag catcctctcc cgcaaccggt
    23041 aagaagctct ctcaactcat caaaagaacg gggagaaggt aacatcggag tcactttcaa
    23101 ccctctgtcc atcaacactt gtttagtttc ctttttatca agagcacgta ataaagcatg
    23161 gggagtattc aaaaagcaca cgtcatcaga taacctcatc tcgcctaaac gttgcagtgt
    23221 ctccttatat gcctgattca acagcgcata tttcaggaaa ttcgtttcat cgcttacaca
    23281 aggttccagt ttgataactg cctgccgtag ttgcggcaag cagttaaaaa gttccccgta
    23341 agtcataaaa cgaacttcca cctgcaagtg tttgcctgct tcaataaagt attctatacg
    23401 tttggacaga gagttgctga caacgattat ctgcatctcc tattctgtaa tcatcgggta
    23461 ataccacaat tcaccatcat attcatctgc ctcttcagtt tcagcaatat ctattttcat
    23521 agggagactc tgcaactgtt tcttcatctc cttgctcaaa taattatagc gcatattgat
    23581 aaacttcaaa tgagcgatct tatccatatt atccagcaat aattgggcac cttcatcttt
    23641 gagagtacca gccgaaacat ccattgtttc aagttgggga agaatatccg actccaggaa
    23701 catttctaca atcttgtcct gttcttcaga gttgacgatc cccagataag tcagcttcgg
    23761 gaaacgttct ttggagaaca acggacggaa tatctcaata tcagcttcaa atccataatc
    23821 ttccacacca acatatagaa tcagtttttc cagattgggg aaatcagaac caagaatatc
    23881 ttctaccact tcggtaggca ggccaccact gataatttcg agtgaccgca actccggccg
    23941 tgaagtcttt cccaaacgca gattattggt tcctttgatt ttcagatctt tcaatttagg
    24001 catggcatcg agcagcggac taatatcagc ttgttcaatc catgaaatct cctgttcttc
    24061 ctgctcaata tctccccaga acaagccttc tatttgtgcg aacttctcct tattttcaat
    24121 cattccctgt aataaggcag aacagtcgcc accctcataa tcccaacaac cgattgttat
    24181 ttgtttatat tcagagagat gtttatcttt ca
//
