LOCUS       gnlProkkaGDLGIGLM_155  14713 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDLGIGLM_155.
ACCESSION   gnlProkkaGDLGIGLM_155
VERSION     gnlProkkaGDLGIGLM_155
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 01:53:49
            Original ID  :: gnl|Prokka|GDLGIGLM_155
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 23468
            Orig. end    :: 38181
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14713
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10348]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14713
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14713
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2711..3043
                     /locus_tag="ctg155_17"
                     /transl_table=11
                     /translation="MVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDC
                     RINLIRFHSIPGVALEGADMDTMTRFRDYLTTHGLFTTIRASRGEDIFAACGMLSTAKQ
                     EENNKS"
     CDS             3088..4098
                     /locus_tag="ctg155_18"
                     /transl_table=11
                     /translation="MALVAFVVASCGLKGNHTSSGRPYELLVVVDAGVWDRAAGRALHD
                     VLDSDMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIVIVDIKDIYTKGTFKYAKDVYAS
                     PQMILTIQAPNEEVFEKFVEENKQTIIDFFTRAEMNRQITLLEEKHNNFISNKVDSLFD
                     CDIWIPSELNNSKTGEDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYFVHKRDSVMK
                     ANIPGYKEGVYMSTDSLLTDVRPINVHNDYTMEARGLWRMKGDFMGGPFVSHTRLDQKN
                     QRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPQEGQQSQIPLGVTREAEPTNK"
     CDS             4103..5197
                     /locus_tag="ctg155_19"
                     /transl_table=11
                     /translation="MEENKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDVQANFSIVNTASEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGNKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEIIIPAMKEMEEKGIICYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAIYVAIDVFRNRQREKAARVN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             5321..6562
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 388.8; E-value:
                     6.1e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg155_20"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFAADFAEKYRMPAIQLTEDAKKI
                     LLAYPWPGNVRQLKNITEQISIIETNREITAAILQTYLPAQNTQRLPALFGTRESKSFE
                     SEREILYSVLFDMRQEVAELKKMVHNMMAERAGQVGQMGQVVATPVVTTTHQPSVPAII
                     HAVQQPSVCPKEDDDDIQDTEEYVEETLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             6663..7076
                     /locus_tag="ctg155_21"
                     /transl_table=11
                     /translation="MKTISIADFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQ
                     NADLQIDGEITGYNQYNQAVSADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTY
                     DSSQLLTAVQDGLIAEMSKEITDQIFNATVANW"
     CDS             7081..7875
                     /locus_tag="ctg155_22"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNL
                     YILHDINFGAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTL
                     ALIDAFLSTAPEEVTSQTSFDYSMDYTAYLLEETPVADEPAEAMPKLKGHELIDNFIEK
                     SETDPVVYLKPLREEEKAKAASSAETNETGRTDETTETNAIEEEDDSCFTETLAKIYVK
                     QQRYSKALEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             7906..8277
                     /locus_tag="ctg155_23"
                     /transl_table=11
                     /translation="MVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRKTTDFLEKA
                     TWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAPQTDATAPA
                     ESAPATEAPATETPAPVAE"
     CDS             8568..9956
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg155_24"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             10001..10348
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg155_25"
                     /sec_met_domain="PF05402 (E-value: 2.8e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1e-09, bitscore: 29.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(10338..10625)
                     /locus_tag="ctg155_26"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(10647..11711)
                     /locus_tag="ctg155_27"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(11785..13296)
                     /locus_tag="ctg155_28"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTSEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAIVETDVSETCFAVPTDTDDYQAVGIGPGLGRSEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             complement(13806..14582)
                     /locus_tag="ctg155_29"
                     /transl_table=11
                     /translation="MSCNDNDDNFSPITLEYEDPQIKFDNESRSYTLTPFSKETTPLFI
                     KGGDGTYKVTNENEKVVQVNYHNGSLTLKAKEIGRASIKIEDSSNNMYILSVVVKYRTL
                     THKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFTFMNAEDSKGTVDLYYSDNN
                     MKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNGKVIDTFYITKNFLPLLNTR
                     MNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
ORIGIN
        1 cgttaataac aaactggttg agaaagaagc aaaagcattg ggactgacag tttctgctgc
       61 tgaaattcag gatatcctga aagcaggcgt gcatccgttg ttgcaacaga ctcctttccg
      121 caacccgcag accggtgctt tcgataagga tatgctcaat aagttcctgg tagattacgc
      181 taaaatgaac gaatctcaga tgccggctca gtatacagaa cagtacaaca acatgtacaa
      241 atactggtca ttcatccaga agacattggt tcagagccgc ctggcagaaa aatatcaggc
      301 attggtagca aaagcgcttc tctctaaccc ggtagaagca caggacgctt tcgacgcaag
      361 agtgaatcaa tatgacttgt tgatggctgc cgttccttat tcttctgtag tagattctac
      421 aatcgttgtg aaagaatcgg aactgaaaga cctttataac aagaagaaag aacagttcaa
      481 gcaatatcag gaaagccgtg atatcaagta cattgatgtt caggtgactg caagtgcgga
      541 agacagagct gctatccagc aggaagtaga cgaagctact gcacagttgg ctactacaac
      601 agatgactat acttctttta tccgctctgt aggctcggaa gctccttatg tagacttgtt
      661 ctataataaa acagctttcc cgtcagatgt agttgcccgt ctggactctg catcggttgg
      721 ttctgtttat ggtccgtact ataatggtgc cgacaatact attaattcat tcaaagtggt
      781 tgcaaaaaca gctgctgccg actcaatcga gttccgtcag attcaggtgt ttgcagaaga
      841 cgctttgaag acaaaagcct tggcggacag tatctatact gctatcaaag gcggtgctaa
      901 cttcgcagat ctggctaaga aatacggtca gacgggtgag actaactgga tgagctctgc
      961 acagtatgaa ggcgcacaga tcgatggtga caacctgaag tttatctctg ctatcaataa
     1021 tacaggcgtg aacgaagtag taaacctgcc gttgggacaa gctaatgtaa tcctgcaggt
     1081 gactaacaag aaagctgtga aggataaata taaagtagct gttgtgaaac gtgaagttga
     1141 attcagcaaa gaaacttata accgtgctta caatgacttc agccagttca tcgctgccaa
     1201 tcctactgct gaaaagatga tcgctaacgc tgaagaagcc ggatacaaac tgcttgacag
     1261 aagagacttg tatagctcag aacacactat cggtggtgta agaggtacta aagaagcatt
     1321 gagatgggca tttgccgcta aaccgggtga tgtttccggt ttgtatgaat gtggcgaaag
     1381 cgaccatatg gttgcagtag ctctggttgg tgttactccg gaaggatatc gtccgctgaa
     1441 agctgtacag gatcagttga gagctgaaat cgttaaagat aagaaagccg aaaagatcat
     1501 ggctgatatg aaagctgcca atgcaacttc tctcgaccag tacaaggcta tgcccggcgc
     1561 agtcagcgat tctttgaagc tggttacatt tgccgctccc gcttatgtct ctgaattgcg
     1621 cagcagcgaa ccgctggtag gtgcttatgc ttctgtggct gaaatgaaca aactgagtgc
     1681 tccaatcaaa ggtaatgccg gtgtatttgt gcttcagatg tatggtaaag acaaactgag
     1741 cgatactttt aacgctaaag atgaagaagc tacattggct aatatgcacg cacgcttcgc
     1801 aagccgtctg atgaacgacc tgtatctgaa aggaaaagtg aaggatacac gttacctgtt
     1861 cttctaagat tagtcgtaaa aacgataact gcaaaaggtc gttccatgct ttggaacgac
     1921 cttttttgct aacttttaca tccttgctat acggaaatcg actttatttc cttacatttg
     1981 caaatataaa ccatgaacag aaagaatgat gtctaaatat cccctcttag gaatgacgct
     2041 tatagagctg cagtcactgg tgaaacgtct gggaatgccg ggctttgcag ccaaacagat
     2101 tgcatcctgg ctttatgata agaaggtgac ttcgattgat gaaatgacta acttgtcgtt
     2161 gaaataccgg gagttactga agcagaacta tgaggtagga gctgaagctc cggtggagga
     2221 aatgcgctct gtagacggta cggtgaaata cctgtaccct gtgggcgaga atcattttgt
     2281 ggagtcggtg tatattccgg atgatgaacg ggcgacttta tgcatttctt cgcaggtagg
     2341 ctgcaaaatg aactgcaagt tctgtatgac cgggaaacaa ggctactctg ccaacctgac
     2401 cgcccatcag attatcaatc agattcactc cttgccggaa cgggacaaac tgacgaatgt
     2461 cgtcatgatg ggaatgggcg aaccgctcga taatctggaa gaggtgttga aggcattgga
     2521 catactgaca gggtcctatg gttatgcatg gagcccgaag cggattaccg tttcaactgt
     2581 cggattgcgg aaaggattgc ggcgctttat cgaagaaagc gactgtcacc ttgccatcag
     2641 cctgcattct ccggtgaccg cccagcgtgc ggaactgatg ccggcggaga aagccttttc
     2701 tatcacggaa atggtggaac tgttaaaaaa ctatgatttt agcaaacagc gtcgactttc
     2761 gtttgaatat attgttttta aggggcttaa tgattcgcaa gtttatgcca aggagttact
     2821 caaactgctt cgcggactgg attgccggat taacctgatc cgtttccatt ctattccggg
     2881 agtagccctt gaaggagccg atatggatac gatgacccgt ttccgtgact atctgactac
     2941 gcacgggctt ttcactacca ttcgtgcttc gcggggagag gatatttttg cggcatgcgg
     3001 tatgctgtcg actgcgaaac aggaggaaaa taataaaagt taatataaaa atcgaacatc
     3061 atgaaaaagt acttttttta tttaagcatg gctttggtag ccttcgtagt tgcttcttgt
     3121 ggattaaagg ggaatcatac ctctagcggt cgtccgtatg aactgttggt tgtagtagat
     3181 gcgggagtgt gggaccgtgc cgccggaagg gccttgcatg atgtgcttga ttctgacatg
     3241 ccgggactgc cccagtcgga accttctttc cggattatgt atacttcacc gaaggactat
     3301 gattctacgc tgaagttgat ccgtaatatt gtgatagtag atataaaaga tatttatacc
     3361 aaaggtactt tcaagtatgc gaaagacgtt tatgcttctc cacagatgat actgaccatt
     3421 caggctccga acgaagaagt gtttgagaag tttgtcgaag aaaacaagca gacgattatc
     3481 gacttcttca ctcgcgctga aatgaaccgt cagattactt tgctggagga aaagcacaac
     3541 aactttatct caaataaggt agatagtctg tttgactgcg atatctggat accttccgaa
     3601 ctgaataact ccaagacagg agaggacttc ttttgggcat ctaccaatac aggcagcgcg
     3661 gatcgcaatt tcgtgatgta ttcttatcct tatactgaca aggatacatt caccaaagaa
     3721 tactttgttc ataagcgcga ttctgtgatg aaagccaata tccccggata taaagaaggc
     3781 gtatatatgt cgacagactc gttactgacc gatgttcgtc cgatcaacgt gcacaatgac
     3841 tacacgatgg aagctcgtgg attgtggcgc atgaagggtg acttcatggg tggcccgttc
     3901 gtttcccata ctcgtctgga tcagaagaac caacgtatta ttacagcaga aatatttgta
     3961 tattcacccg ataaaatgaa acgcaatctg gttcgccaga tggaagcatc tctttatacg
     4021 ctgaaacttc cgcaagaagg tcagcagagt cagattccac tgggggtaac cagagaagcg
     4081 gaaccaacta ataaataaaa acatggaaga aaacaaaata agaatcggca ttacccaagg
     4141 agatatcaac ggggtaggtt atgaagtgat cttgaagaca ttctcagacc ctaccatgct
     4201 tgagctatgt actccgatta tctacggttc acctaaagta gcggcttacc atcgtaaagc
     4261 actggatgta caggctaatt tcagcattgt caacacagct tccgaagccg gatacaaccg
     4321 tctgagtgta gtgaactgta cagatgacga agtgaaagtg gaattctcca aacccgatcc
     4381 cgaagcaggt aaggctgcat tgggtgcttt ggagcgtgcc atagaagagt atcgtgaggg
     4441 gctgatcgac gtcattgtga cagctccgat caacaaacat accattcagt cggaagagtt
     4501 ctctttcccc ggtcatacgg agtatattga agaacgtctg ggcaatggaa acaagtcact
     4561 gatgatcctg atgaaaaacg attttcgtgt ggctttagta acgacgcata ttccggtaag
     4621 ggagattgct acaacaatca ccaaggaact gattcaggaa aagctgatga ttttccatcg
     4681 ttgtctgaaa caggatttcg gtatcggtgc gccccgtatt gcagtgcttt cactgaatcc
     4741 tcatgcagga gacggtggac tgctaggtat ggaagaacag gaaatcatta tccctgccat
     4801 gaaagaaatg gaagagaaag ggatcatctg ttacggtcct tatgctgcgg acggttttat
     4861 gggttcgggc aattatactc actttgacgg aatccttgct atgtatcatg atcagggact
     4921 ggctccgttc aaagccctgg ctatggaaga cggtgtgaac tataccgccg gactgccggt
     4981 tgtacgtacc tctccggctc atggaacagc ctatgacatc gccggtaaag gactggccag
     5041 cgaagactct ttccgccagg ctatttatgt agcgattgat gtattccgca accgccagcg
     5101 cgagaaagcg gcacgggtaa acccgttgcg gaagcagtat tacgagaaac gggacgatag
     5161 tgataaacta aaactggata cagtagacga agattaagta ataggtatta agtaataagt
     5221 attaagtatt agccatgcgg atggaagcga gatgataatg atggtaatac ttaatactta
     5281 ttacttaata cttattacct attacttaat attaagatag atgaccaaag cggagataca
     5341 acaagtgaaa cagcgtttcg gtattattgg caataccgag gctttatcac gtgccataga
     5401 tgttgccatt caggtagcgc ctaccgattt gtctgtgctg attaccggag aaagtggtgt
     5461 cggaaaagaa agttttccac agatcattca tcaatatagc cggagaaagc atgggcagta
     5521 tattgctgtc aactgtggtg ccataccgga aggtacgatc gattccgaac tgttcggaca
     5581 cgagaaagga gcatttaccg gtgctattgg tgagcggaaa ggatattttg gagaagctga
     5641 cggtggaact atcttccttg atgaagtggg agagttgccg ttgcctacac aggcgcgtct
     5701 gctccgtgta cttgaaagcg gtgaatttat caaggtaggt tcatccaaag tgcaaaagac
     5761 ggatgtacgt attgtggcag cgaccaacgt gaacctgaca caagccattg ccgaaggacg
     5821 cttccgggaa gatttgtatt atcggttgaa cacggtgcct attcagatac cacctttgcg
     5881 tgagcgtgga gatgatgtgc tgttgttgtt ccgtaagttt gccgcagact ttgccgaaaa
     5941 gtaccggatg ccggctatcc agctgacgga agatgccaag aagatattgc ttgcttatcc
     6001 gtggccggga aacgtccggc agttgaagaa catcacagag caaatttcga ttatagaaac
     6061 aaaccgtgag ataacggctg cgattctgca gacctatctt ccggcacaga atacccaacg
     6121 ccttccggca ctgttcggca cacgcgagag caagagcttt gagagcgaac gcgaaatact
     6181 atattctgtc ttgttcgata tgcgtcagga agtggcggaa ctgaagaaga tggtgcacaa
     6241 tatgatggct gaacgtgcgg gacaagtcgg acagatggga caggtagtag ctactccggt
     6301 agtgacaacg acgcaccaac cttccgtgcc ggccattatc catgctgtgc agcaaccgtc
     6361 tgtttgtccc aaagaagacg atgacgatat tcaggacacg gaagaatatg tagaagaaac
     6421 cctttcgctc gatgaagtgg aaaaagaaat gatacgtaaa gcgcttgaga ggcatcatgg
     6481 taagcggaaa agtgcggcga aggatctgaa tatctccgag cgtacccttt acagaaaaat
     6541 aaaagaatat gaattggatt aagaaaatag cacgaccgct gatattggtt gttttaccgg
     6601 cagtcatcat cgcctgtagt gtgtcctata agtttaatgg ctcctctatc aattacgata
     6661 aggtgaagac tatttcgatt gctgatttcc cgattaagtc ggagtatgtg tatgctccgc
     6721 tggctaccaa gttcaatgaa gacctgaaag atatcttcat cagacagacc cgtctgcaac
     6781 tgctgaaacc gaaccagaat gcggatctgc agattgacgg tgaaattacg ggctacaacc
     6841 agtataacca ggcagtgtct gccgatggtt actcttcgga aacgaagctg accatcacgg
     6901 tcaatgtacg ctttgtcaac aacacaaatc acgccgaaga cttcgaacaa caattctcag
     6961 ctttccgtac ctatgattcc agccagctgc tgacagccgt acaggatgga ttaatagcgg
     7021 aaatgagtaa agagataacc gaccaaatat ttaatgcaac tgtagcaaac tggtaattta
     7081 atgacttctg ttaacttgca acaatggatt cagcatcccg agacgctgaa tagggatact
     7141 ttgtacgaac tgcgcaacca gctcgcgagg tatccgtatt ttcagtcgct ccggttgttg
     7201 tatctcaaga acctgtatat tctccacgac attaatttcg gtgcggaact gcggaaagcc
     7261 gttctgtata ttgccgaccg acggaaactg tttcatctga tcgaaggcga acgcttcgct
     7321 gtcgaatccc agaagaaagg gttgcctctc tctgaagtat tgaaagatga gcctaccgtc
     7381 gaccgaacac tggctctgat cgatgctttt ctttcgacgg ctcccgaaga agtaaccagt
     7441 cagacaagct ttgattactc tatggactat acggcatacc ttctcgaaga gacacctgtc
     7501 gccgacgagc cggcagaggc aatgcccaag ctgaaaggac acgagctgat tgacaacttt
     7561 atcgaaaaaa gcgagactga tccagtcgta tacctgaaac ctttgaggga agaagagaaa
     7621 gcaaaggcag cttcttccgc tgaaacaaac gaaacgggca gaacagacga aacaactgaa
     7681 accaacgcca tagaagagga agatgacagc tgtttcacag aaactttggc caaaatctac
     7741 gtaaaacagc aacgatattc gaaagctctt gaaataatta aaaaattaag cttgaaatat
     7801 ccaaaaaaaa atgcttactt tgcagaccaa atcagatttt tggagaaatt gattattaac
     7861 gctaattcaa aataactaaa aatgtactta ttattcatta tcttaatggt gattgcagcc
     7921 ttgctgatgt gcttcatcgt gctgattcag aattcaaaag gaggcggact tgcttctggt
     7981 ttttcttcat caaacgctat catgggcgtg cgcaagacta cagattttct ggaaaaagca
     8041 acttggggtc tggctatctt catggttgtg atgagcgttg ctactgctta cgttgttcct
     8101 tcttcttctg cggctaaaga tgtattgttg gaacaagcac agaaagaaca acaaaccaac
     8161 ccgtataata tgcctaccgg tactgctgct cctcagacag atgctactgc tcctgcagag
     8221 tctgcaccag caacggaagc tccggctact gaaactcctg ctcctgtagc agaataattc
     8281 agtgacagga tattcggttt aaacttattg agtgaacggg ctttttgacc cgttctcttc
     8341 attataggcg cgaattacgc gaattacaag agattctaat agaatcgtgt aatacgtgta
     8401 gttcgcgcct gtctttatta ttgggcccgg tctgctcttc ttcatacagg aatatccggt
     8461 cagatgtcct ttttcttata aaatgttctc cttttttagt aaaacaaatg ataattagtt
     8521 aactttgttg cccgttacga gattattaac tccttttaaa tattacaatg acagaacaat
     8581 tgaaacaaaa gctgaatgac tccgcagtgc tgcgttggag tgttctagca ttagtcgctt
     8641 ttaccatgtt gtgcggctac ttcctcacag acgttatgtc tcctctgaaa cccatgcttg
     8701 aaaaagaact tctctgggac agtttagatt acggtttttt caccagtgct tatggctggt
     8761 ttaatgtatt cctgctgatg ctcatctttg gtggtatcat tctggataag atgggagtac
     8821 gcttcaccgg aatgggtgcc tgtttattga tggtgttcgg ttgtggattg aaatattatg
     8881 ctattactac tactttcccg gaaggtgcga tgcttttcgg attcaagatg caagtcacat
     8941 tggctgcatt gggttatgct attttcggtg taggagtcga aattgcgggt atcaccgttt
     9001 cgaagattat cgtgaagtgg tttaaaggca aagagatggc tctcgctatg ggactggaaa
     9061 tggcgaccgc gcgtattgga acgactttgg ccatggtgct taccgttcct ttggcagact
     9121 tcttcgggtc tacggatgag agcggcgtat tccataccaa tattcccgct ccgattctgt
     9181 tctgtctcgt catgttgtgc gtaggtacca tcgcattctt catctatact ttctacgata
     9241 agaaactgga tgcttcactg gatgcggaag gactggaacc ggaagaacct ttccgcatga
     9301 aagacattgt ctatatcatt accaacaaag gattctggct gatcgcatta ctgtgcgtat
     9361 tgttctattc ggctgtattc cccttcatca agtatgcggc cgatttgatg gtacagaagt
     9421 acaatgttga tccgaaactt gcgggaacga ttcccggatt gctgccgatt ggcgcgatca
     9481 tcctgacacc gttgttcggt tcattgtatg accgtatcgg taagggagcc acgctgatgg
     9541 tgatcgggtc ggtgatgctg attttcgtac acacgatgtt cgctcttcct attctgaata
     9601 tatggtggtt tgcaacggtg atcatgatta ttctgggatt tgctttctca ttggttcctt
     9661 cggcaatgtg gccttcggtt ccgaagatta ttccggagaa acagttggga acggcttatg
     9721 cgttgatctt ttgggtacag aactggggat tgatgggcgt gcctttgctg atcggatggg
     9781 tgttgaactc ttattgcaaa ggtccggttg tagatggtgc acagacttat gattatactt
     9841 tgccgatggc tatttttgct atgttcggtg tacttgccct gattgttgcc ttgatgctga
     9901 aagtggaaaa caagaagaaa ggctacggac tggaagaagc aaatattcag aaataatcac
     9961 agtatatatt ctatctgaaa agatataaaa gagaaaagat atggctacga aagagaaaat
    10021 aaacctcctg gaggtgatcc cttgtcgtaa cgaacatatt aaagctgaac aggaagggga
    10081 gactattgtg ctctccttcc ctcgttttaa acgttcgtgg atgagtcgtt atttattgcc
    10141 gaaaggaatg tccaaagata ttcatgtgcg tctggaagaa cacggtacgg ctgtatggaa
    10201 cctgatagac gggcagcgga cggttcgtga gattatagaa aaactcgcag accactttca
    10261 atatgaagca ggctacgagt ctcgtgtatc tacctatctt tcccaattac agaaagacgg
    10321 atttattaaa tggataatta tccattaaaa aagattgccc acaagaggac agcacatcct
    10381 atcagtacgc ccataatgat gagcgttccc catacgaaat agctgttatc tttttctttt
    10441 ttcttttccg aatccttgat gatgcgttcc atctcttccg gagtcgtatc cggcagaaga
    10501 taagggtcgt tgtttcttct aagtcgccct aacttgtcat ttctccgttc acggcgtaag
    10561 cgggaggctt ctttgccgtc tttcagccga cgtatcatgt cgagcatatg tccttcgcca
    10621 cccatcgttt tgttttttta gaggttttat ttgctttctt ctctatctac tttcagtagt
    10681 ccaccggtca ccggatcaaa gtaaactttg atggtcgagt tcttgttgaa taataccgga
    10741 gcaaggtatt ctatgatacc gaactgagta acaggtattt ctccttcata caatttcttt
    10801 ttgccgtccg tcagcgtcac cattgcctgt cccggtacgt tataagcaat gccttccatc
    10861 tctttcttct ttttcccgtc ctcttgcgga atcttcaccg ttttcaggtc tttcagactg
    10921 atgtagaatg gagtgcctgc caaatcgttg ttggcaacta tacccagctt ctttgaaaag
    10981 cggaaagcta cctcattgtc gaattcctta tccggagtga ggcggacagt aaatgtcttt
    11041 tcttctttat tgcggactcc cgaaaacatc tcggtcatgg cttcttcctg aagattcaag
    11101 ttgtcgagca tgattttgag ctgtgcgccg tccgaaggca tattatctgc ttgtccgcgc
    11161 aataatgcgt ttttactttc gcggatatta tagatttcct ttgctaccag ttcggccatc
    11221 ttggcggttg aacttgccat cagaatttct tcggtgagaa agtcgcgggg attggctttt
    11281 cgttggggag caacggcatt gtttgctgca ttctttgcat tgttactact gtaggggacg
    11341 ttgatcgatt tgataagacc ctcttcagtc agttccataa gaggagctac ggttttatct
    11401 ttcagtttga cgaaataagt agcttcgctg tttggtacac ctacaggttt cactttgacg
    11461 ctgttcaatt cccagtattc ttcgggttcg gcagagacgt tggtcagtct caggtagcgg
    11521 tcggcgtatt tgctgaattc acccggctta tagttgactt tgtttgcttt tatttctatt
    11581 tctatctggg ttttggggag ggcgtacact actccgtagt cttttcctcg cgtcactcct
    11641 gtcagcactt cggtctgcgc ataggcggaa gttgccatta gtagtcctgt tgctatgatt
    11701 aactttttca tattcggttc tttttagctg attttgaaaa acaaagttaa tgaagttatt
    11761 gaataaaccg taagttctta acttttattc gcttacaagt cgccatgccg tcggcagaca
    11821 ggtcacgata tcacttgcga ttaatccgat catgccctgc tttttctggg cgatgtctcc
    11881 ggccaatccg tgaatgtaag taccgatctt tgcggcatct tcggcaggat agccttgcgc
    11941 aagaagtgcc aggattactc ctgtcagtac gtctccgctg cctcctgttg ccataccggg
    12001 attaccggtt tggttgaagt aacatttgcc ttcgggggtg ataatggcgg aataagctcc
    12061 cttcagaatg atatgtactt tggcagtgtg cgccagttcg caggctttca tgagtcgttc
    12121 gtatgagtcc tgacatttgc cgaccaggcg ttccagctct ttcgggtgag gggtgaggat
    12181 ggaacctttc ggcagatggg tgagcgtatg ccggtgattg gccagaatat tgagtgcgtc
    12241 ggcatccagt actgtcggag tctgacaatg ttccagttgt tctatcaagg cggcttccgt
    12301 ttcctcgctg cgaccgagtc ccggaccgat gccgacagct tgataatcat ccgtatcggt
    12361 aggtacggca aagcaagttt cgctgacatc tgtttctact atggcttcgg gggcagacgt
    12421 ttgcagaata tcgttgttgc ataacggcgc gtgtacggtc agcagaccta ctcccgagcg
    12481 cagacaggca cgcgcggcca gtaccgatgc acctgccatt ccttttgaac cggctatcag
    12541 cagggcatgt ccgaagtttc ctttatgggc gaattgttgg cgtggtttga tcagtgaacg
    12601 gatttcttcg atttccagca tttcgtagtt tgtttcagtc tcttcgattc cttcttcgct
    12661 cagctggatg tccaataact cccattcgcc aacaaattct gtattttcgg caaagaggaa
    12721 ggccagttta ggaagttgca ggctgaaagt gacgtccgca cggataatat tgctttttac
    12781 attgaatgta ttttcttctc ccatcagccc ggaagggatg tcgatggaga ctaccatggc
    12841 gggagaggca ttgatatatt tcacaacggc agcgaatcct ccgctcaatg gtttgttgag
    12901 tccggaaccg aataatccgt cgatcacgag atgctccgat gtcagtgtgg gcggtacgaa
    12961 ctgggtgctg atttcatgga aagttacttc ttccatcatc tctaccagtt ctttgttggt
    13021 ctggcagtcg ggcgaaagtt cgcctttcgt gttgaagaga tatacttcga tcttgtatcc
    13081 tttttccgcc atcatgcggg cgatggcgag ggcgtctccg ccattattgc ccggtccggc
    13141 aaagatggtg acaggtgttt ccggattcca tctgttagtg atggctttag tcagcgcctg
    13201 tgcggcacgt tccattaaat caatggatgc aatcggttca tgttcaatgg tataggcatc
    13261 taacttctta atgctgctgc ttggaaatat tttcattgcg atattctttt agttttcgac
    13321 gcacaaactt acacaaaaac tctgaattaa tcctttattc cggttggttt tcggcttttt
    13381 gggaaggaac ttcaggtatt aatagttgat gtgtcagtta ttaatagttg agaagtcaga
    13441 tattaatgat tgttatggta gatatcaatg cttgttatga tggctttcaa tgcttgtaac
    13501 gcagtataac aagcattgtt atctcattta cttttactct ctccggagaa cattcatggc
    13561 tgtttgttaa ccttcccatg cgtgtttcta ctactgtata ttcctctggt tcacctcttt
    13621 cacccgcaat cgccttattt atcaaaggtt caggaaaagg gtggaagagg tgattgtgat
    13681 aaatatgcta tgggcatatt cttgattagc taatagctta ttgttttttg ctaaatctaa
    13741 tggggagttt gctcatataa taaatactct attcactctg ctaaagaaga aaatcagtgt
    13801 agctctcatt ctgctatttg aatcagatat gcattttcca gtgcaaggta atcttgtttg
    13861 tactgtgcgg ttaaatctct gacaaaacag tactgaatta acggatgagc attcattctt
    13921 gtattgagga gtggtagaaa gttcttggta atatagaaag tatcaataac tttgccatta
    13981 tcttctttga ttgttatacg gtaatactca ctcaatttgt attcaccttt gatgggaatg
    14041 gcattttctt catccagcac tatatgttct ttttcaaagt tgcctgtttt catgttatta
    14101 tctgaataat acaaatctac tgttcctttg ctgtcttccg cattcataaa agtaaataca
    14161 tatttattaa tcggatatga attgcccact ttgttcatta actcagtgtg ttcttcagat
    14221 gtaagctcgt ctcccttcac aatgactttt gctgtaaacg ccttatgagt aagagtacga
    14281 tattttacaa cgacagacag tatatacata ttattcgaac tgtcttctat cttgatggat
    14341 gcgcgtccta tttcctttgc cttcaatgtt aaacttccgt tgtggtagtt tacttgtacc
    14401 actttctcat tctcattggt cactttgtaa gttccgtctc cacccttgat aaagagtggt
    14461 gtcgtttctt tgctgaacgg agttagtgtg taagaacggc tctcgttgtc gaacttaatt
    14521 tgaggatctt catattccag agtgattgga gaaaagttgt catcattgtc attacagctc
    14581 acgaggcaaa taatacaaag aaataacgaa agtattcctg ttagtttttt ggtagtcatg
    14641 ctaattaaag ttttaaatgt gcgatattag tttagttctc gtctgcaaac ttatgaaaaa
    14701 gaattgaact gtt
//
